CN107157804A - A kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof - Google Patents
A kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof Download PDFInfo
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- CN107157804A CN107157804A CN201710590646.3A CN201710590646A CN107157804A CN 107157804 A CN107157804 A CN 107157804A CN 201710590646 A CN201710590646 A CN 201710590646A CN 107157804 A CN107157804 A CN 107157804A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4933—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having sulfur as an exocyclic substituent, e.g. pyridinethione
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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Abstract
The present invention discloses a kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof, in percentage by weight, including following components：Basic components 2 ~ 6%；Nutrition composition 0.4 2.3%；Energy component 0.55 ~ 2.8%；Anti-dandruff component 0.3 ~ 0.7%；Antiseptic ingredient 0 ~ 2.0%；Water surplus.Nutrition scalp hair follicles hair tonic elite provided by the present invention, really play moist nutrition scalp, hair follicle, healthy hair effect, moisture-keeping nutrient conditioning is given from hair depths, it is obviously improved natural on-off cycles of hair growth environment, the quick healthy growth of hair is made, toughness, elastic force and the gloss of hair, tough root of hair is more can effectively improve.
Description
Technical field
The present invention relates to daily chemical product field, a kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof is related generally to.
Background technology
With the continuous improvement of people's living standards, to beautiful pursuit also more and more higher, but air pollution, Working Life pressure
Power such as increases at the factor can all cause great damage to scalp and hair-care, and time length can cause the appearance of hair loss depilation phenomenon.In addition,
People be commonly used shampoo and hair conditioner, but at present on the market wash shield product, be largely containing silicone oil（Silicone oil alkane is produced
Product）Composition, silicone oil component is widely used as the conditioner commonly used in hair conditioning.But, being used for a long time can be in head
Excessive buildup is produced on hair, the environment of natural on-off cycles of hair growth becomes increasingly worse, is unfavorable for the healthy growth of hair.Current preparation for baldness
There is also risk, such as methylisothiazolinone, methylchloroisothiazandnone, methyl hydroxybenzoate etc. in the preservative safety used,
During first two composition is forbidden being used to be resident product since the whole world 2017, it is seen that its security is into very big problem.
Although someone product for improving hair-growing add to natural on-off cycles of hair growth rise opsonic action composition, such as Minodl,
Finasteride etc. has secured permission, but comparison of ingredients is single, and Western medicine can cause drug dependence, does not neutralize consideration
The overall situation, it is nursed one's health, and hair-growing effects are fairly limited, and no scalp, hair follicle, root of hair combine well accounts for, institute
Hair tonic product is lost the confidence with common people.And exist many using limitation, such as using effect, excitant and stability problem
Deng；How while scalp is not stimulated, preferably hair tonic conditioning effect is realized, is current nutrition scalp hair follicles hair tonic elite group
Compound studies urgent problem to be solved.
Therefore, prior art has yet to be improved and developed.
The content of the invention
In view of above-mentioned the deficiencies in the prior art, it is an object of the invention to provide a kind of nutrition scalp hair follicles hair tonic elite and
Its preparation method, the nutrition scalp hair follicles hair tonic elite, which combines scalp, hair follicle, root of hair, to be accounted for, and is integrally changed
The growing environment of kind hair, while scalp is not stimulated, realizes preferably hair tonic conditioning effect, it is intended to solve existing hair tonic production
The problem of product are limited to the opsonic action of hair tonic.
Technical scheme is as follows：
A kind of nutrition scalp hair follicles hair tonic elite, wherein, in percentage by weight, including following components：
Basic components 2 ~ 6%；
Nutrition composition 0.4-2.3%；
Energy component 0.55 ~ 2.8%；
Anti-dandruff component 0.3 ~ 0.7%；
Antiseptic ingredient 0 ~ 2.0%；
Water surplus.
Wherein, the basic components include glycerine, xanthan gum, carbomer sodium, EDTA-2Na, hydroxyethyl cellulose；Nutrition
Component includes vitamin B3, allantoin, D-pantothenyl aleohol, vitamin A, biotin；Energy bins point include caffeine, carnitine, smart ammonia
Acid；Anti-dandruff component includes salicylic acid and Octopirox；Antiseptic ingredient includes Phenoxyethanol, hexylene glycol and para hydroxybenzene second
Ketone.
Described nutrition scalp hair follicles hair tonic elite, wherein, the nutrition scalp hair follicles hair tonic elite, according to weight percent
Than meter, including following components：
Basic components：
Glycerine 1.3 ~ 3.63%；
EDTA-2Na 0.02~0.07%；
Carbomer sodium 0.38 ~ 1.5%；
Xanthan gum 0.1 ~ 0. 3%
Hydroxyethyl cellulose 0.2 ~ 0.5%；
Nutrition composition：
Vitamin B3 0.1 ~ 0.5%；
Allantoin 0.1 ~ 0.5%；
D-pantothenyl aleohol 0.1 ~ 0.7%；
Vitamin A 0.05 ~ 0.3%；
Biotin 0.05 ~ 0.3%；
Energy component：
Caffeine 0.3 ~ 1.5%；
Carnitine 0.05 ~ 0.5%；
Arginine 0.2 ~ 0.8%；
Anti-dandruff component：
Salicylic acid 0.1 ~ 0.3%；
Octopirox 0.2 ~ 0.4%；
Antiseptic ingredient：
Phenoxyethanol 0 ~ 0.5%；
Hexylene glycol 0 ~ 0.5%；
Parahydroxyacet-ophenone 0 ~ 0.5%；
Water：Surplus.
Described nutrition scalp hair follicles hair tonic elite, wherein, the nutrition scalp hair follicles hair tonic elite, according to weight percent
Than meter, in addition to following components：
Perfume ingredient 0 ~ 0.50%.
Perfume ingredient includes essence and solubilizer polysorbate -20.
Described nutrition scalp hair follicles hair tonic elite, wherein, the nutrition scalp hair follicles hair tonic elite, according to weight percent
Than meter, in addition to following components：
Perfume ingredient：
Essence 0 ~ 0.10%；
Polysorbate -20 0 ~ 0.40%.
A kind of preparation method of nutrition scalp hair follicles hair tonic elite as described above, wherein, comprise the following steps：
Water and basic components, dispersed with stirring are added in a kettle., 75-85 degree is heated to, and insulated and stirred 15-30 minutes treats solid
Phase thing starts cooling after all dissolving is scattered；
Temperature adds nutrition composition and anti-dandruff component, insulated and stirred 10-20 minutes when being down to 50 degree, makes it be uniformly dispersed, after
It is continuous to cool；
Temperature adds energy component when being down to 45 degree, continues dispersed with stirring uniform；
Temperature sequentially adds perfume ingredient and preservative component when being down to 40 degree, and dispersed with stirring is uniform；
The moisture of polishing evaporation, stirs, filtering and discharging is produced.
Beneficial effect：The present invention nutrition scalp hair follicles hair tonic elite, by nurse skin theory with nursing scalp on,
And scalp, hair follicle, root of hair combine accounted for, anti-dandruff, addition temperature is considered while Nutritional Nursing Care scalp
The preservative component of sum, it is to avoid former preparation for baldness effect component is single, the problem of not considering the overall situation, improves conditioning
Hair-growing effects.Scalp hair follicles are taken good care of, and growing environment obtains improving hair with regard to healthy growth, grows pitch-black healthy hair.This battalion
Support scalp hair follicles hair tonic elite and really play moist nutrition scalp, hair follicle, healthy hair effect, give moisture-keeping nutrient from hair depths and adjust
Reason, hence it is evident that improve natural on-off cycles of hair growth environment, make the quick healthy growth of hair, more can effectively improve hair toughness, elastic force and gloss,
Tough root of hair.
Brief description of the drawings
Fig. 1 is comparison diagram of the caffeine in skin surface permeability.
Fig. 2 is free mirror image figure of the caffeine under 100 times of magnifying glasses.
Fig. 3 is mirror image figure of the basic components containing caffeine under 100 times of magnifying glasses.
Embodiment
The present invention provides a kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof, to make the purpose of the present invention, technology
Scheme and effect are clearer, clear and definite, and the present invention is described in more detail below.It should be appreciated that described herein specific
Embodiment only to explain the present invention, is not intended to limit the present invention.
Nutrition scalp hair follicles hair tonic elite provided by the present invention, by nurse skin theory with nursing scalp on, and
Scalp, hair follicle, root of hair are combined and accounted for, considers that anti-dandruff, addition is gentle while Nutritional Nursing Care scalp
Preservative component, it is to avoid former preparation for baldness effect component is single, the problem of not considering the overall situation, improves conditioning life
Send out effect.And preservative mildness is improved, the excitant to scalp is reduced.Nursing scalp picture shield has been newly increased in the present invention
The same theory of skin is managed, scalp hair follicles are taken good care of, growing environment obtains improving hair with regard to healthy growth, grows pitch-black healthy hair
Come.This nutrition scalp hair follicles hair tonic elite really plays moist nutrition scalp, hair follicle, healthy hair effect, gives and protects from hair depths
Wet nutrition recuperating, hence it is evident that improve natural on-off cycles of hair growth environment, make the quick healthy growth of hair, more can effectively improve toughness, the bullet of hair
Power and gloss, tough root of hair.
Specifically, the nutrition scalp hair follicles hair tonic elite, in percentage by weight, including following components：
Basic components 2 ~ 6%；
Nutrition composition 0.4-2.3%；
Energy component 0.55 ~ 2.8%；
Anti-dandruff component 0.3 ~ 0.7%；
Antiseptic ingredient 0 ~ 2.0%；
Water surplus.
Wherein, the basic components are made up of glycerine, xanthan gum, carbomer sodium, EDTA-2Na, hydroxyethyl cellulose.Battalion
Component is supported by vitamin B3, allantoin, D-pantothenyl aleohol, vitamin A, biotin.Energy bins point include caffeine, carnitine, arginine
Composition；Anti-dandruff component is made up of salicylic acid, Octopirox.Antiseptic ingredient is by Phenoxyethanol, hexylene glycol and para hydroxybenzene
Ethyl ketone is constituted.
Specifically, the nutrition scalp hair follicles hair tonic elite, in percentage by weight, including following components：
Basic components：
Glycerine 1.3 ~ 3.63%；
EDTA-2Na 0.02~0.07%；
Carbomer sodium 0.38 ~ 1.5%；
Xanthan gum 0.1 ~ 0. 3%
Hydroxyethyl cellulose 0.2 ~ 0.5%；
Nutrition composition：
Vitamin B3 0.1 ~ 0.5%；
Allantoin 0.1 ~ 0.5%；
D-pantothenyl aleohol 0.1 ~ 0.7%；
Vitamin A 0.05 ~ 0.3%；
Biotin 0.05 ~ 0.3%；
Energy component：
Caffeine 0.3 ~ 1.5%；
Carnitine 0.05 ~ 0.5%；
Arginine 0.2 ~ 0.8%；
Anti-dandruff component：
Salicylic acid 0.1 ~ 0.3%；
Octopirox 0.2 ~ 0.4%；
Antiseptic ingredient：
Phenoxyethanol 0 ~ 0.5%；
Hexylene glycol 0 ~ 0.5%；
Parahydroxyacet-ophenone 0 ~ 0.5%；
Water：Surplus.
Nutrition scalp hair follicles hair tonic elite provided by the present invention, with rational percentage by weight by basestocks, nutrition into
Divide, energy ingredient, anti-dandruff component, perfume ingredient, preservative ingredient are prepared, wherein, the key of nursing role is played to natural on-off cycles of hair growth
Composition is embodied in nutrition composition, and nutrition composition, the rapid deep zone of energy component are absorbed, and other auxiliary elements are adsorbed in well
Coordinative role is played at scalp and hair.Battalion is played to scalp and hair follicle especially with multivitamin B3, B12, A and D-pantothenyl aleohol
Effect is supported, compounding energy component caffeine, carnitine, arginine supplement scalp cells and the more energy of hair follicle cell also add
Plus anti-dandruff component solves dandruff and inflammatory phenomena so that the long work(for reaching moist moisturizing and nutrient energy occurs for said composition enemy
Effect.In the case of without anticreep plant extraction liquid, can deep layer nourish hair of scalp, hence it is evident that improve natural on-off cycles of hair growth ring
Border, nutrition and energy needed for supplement natural on-off cycles of hair growth, hair quickly grows new hair, and denser, while healthy hair is moist, strong
It is strong, high resilience, and make user more receptive.In addition, with the addition of the anti-dandruff combination of safe and reasonable, dandruff quantity is reduced,
The good nutrient environment of bacteria breed is eliminated, the possibility that bacterium has lacked scalp hair follicles generation inflammation just lowers significantly；Also
There are the glycerine in basic components, carbomer sodium to play deep moisturizing effect to scalp, hair, and ventilative taste is formed in hair surface
Moisten moisture film, also the absorption of guarantee nutrition composition and energy component is slow over time to discharge scalp, hair in moisture film
Required energy matter and nutrient, just true moisturizing nourishing hair is given hair follicle, scalp from depths and given pain taking care, is
Hair healthy growth provide scientific nutrition combination, adhere to using can hair can be made to keep fit, light, high resilience, strengthen head
The toughness of hair.
Applied after hair washing when hair is half-dried and spread nutrition scalp hair follicles hair tonic elite, and fully massage absorbs, user
Just, and elite can be rested on hair and scalp for a long time, thus deep layer moistens nourishing hair, gives hair nutrition conditioning and repaiies
Shield is acted on, and makes hair denser, pitch-black, moist, strong.Further, since using gentle formula, even if resting on for a long time
On scalp and hair, will not also stimulation be produced to scalp, allergic phenomena occur.Nutrition scalp hair follicles hair tonic elite of the present invention also may be used
Shampoo is coordinated to use, sticky sense somewhat, massage absorption can also be rinsed after finishing with water or shampoo is rinsed because product has.
Allantoin promotion organization grows, cell metabolism, cutin-softening layer albumen.D-pantothenyl aleohol, vitamin B5 precursor, again
Claim the nursing role on dexpanthenol, skin to show as the NMF penetrated deep into, stimulate the growth of epithelial cell, promote wound
Mouth healing, plays antiinflammation；Nursing role on hair shows as lasting moisture-keeping functions, prevents hair jag, is damaged, increase
The density of hair, improves the gloss of hair quality.Vitamin A（vitaminA）Also known as retinol, vitamin A is added as nutritional ingredient
Agent, can prevent pachylosis, promote normal growth and development, contribute to cell propagation and growth, safeguard the strong of Epithelial cell
Health and the synthesis for promoting immunoglobulin, can help to prevent and treat alopecia.Carnitine（CARNITINE）, the fortune of carnitine promotion aliphatic acid
It is defeated to promote the utilization of carbohydrate and amino acid with oxidation, improve body tolerance, prevent lactic acid accumulation, it is anti-aging, anti-
Oxidation.Vitamin B3, also referred to as nicotinic acid, nicotinic acid have stronger expansion peripheral vessels effect, stimulate circulation.Biotin, also known as
Biotin, biotin, biotin safeguard the normal operation and growth of skin and hair, mitigate eczema, dermatitis symptom；Prevent white hair
And alopecia, contribute to treatment bald.Arginine Chinese name L-arginine, arginine is also the main component of sperm protein, there is rush
Enter Sperm specific enzyme, improve the effect of sperm motility energy.Salicylic acid, salicylic acid can be as cosmetics preservative, also can be as going
Bits agent is used, and effect is pretty good.Octopirox, with remarkable antipruritic effect, is offseted except pruitus has original effect,
It can effectively kill the mushroom for being born in skin, and have and special go body odor effect.
Caffeine, for supplementing scalp cells and the more energy of hair follicle cell.Caffeine is a kind of xanthine alkaloid
Compound, central nervous excitation agent can temporarily drive away sleepiness and regain one's vigor, clinically for treating neurasthenia and dusk
Fan's recovery.Caffeine can suppress 5 alpha-reductases, and prevention changes into protona, and this is relevant with alopecia.This enzyme is widely present in
In epidermal keratinocytes and hair papilla cell.Caffeine enhances intracellular ring-type AMP（Cyclic phosphate adenosine）Level,
Hair follicle stimulating is metabolized, and suppression can cause the DHT that hair follicle diminishes.In topical application, free caffeine can ooze in very short time
Penetrate into blood, it is very short in skin residence time.And just solved this problem in that using basic components of the present invention, enable caffeine
Slowly discharge and target through root hair follicle.The basic components of the present invention, can wrap up orientation by caffeine and be transported to hair follicle
Position, forms the container of a slow release caffeine, maintains prolonged curative effect；With following 3 advantages：1st, it can encapsulate
The caffeine of high content, extends release time, heightens the effect of a treatment；The 2nd, caffeine targeted release is delivered to the hair follicle needed most deep
Place；3rd, it is easy to prepare, formula is gentle stable.In the present invention, the design concept of orientation conveying, specifically refers to hair follicle mouthful straight
About 30-50 microns of footpath, and only 0.8 micron of the container diameter of caffeine is enclosed with, hair follicle can be penetrated into, more targetedly, is increased
Strong curative effect.In order to prove slow release effect of the caffeine in the basic components, according to the basic components and coffee in embodiment 4
The raw material and proportioning of cause are made into basic components, using basic components and caffeine mixture as experimental group, with free coffee because
Control group, carries out the experiment of release in vitro control, in 6 hours of detection, the contrast that experimental group and control group are remained in vitro, knot
Fruit as shown in figure 1, Fig. 1 testing result for caffeine in skin surface permeability, permeability it is higher represent residual rate it is lower, lead to
Cross contrast, it can be clearly seen that the speed that experimental group discharges in vitro is slower than the effect of control group, the effect with sustained release.Will
Control group and the caffeine of experimental group are placed to be analyzed under the microscope, and Fig. 2 is that display 10% dissociates under 100 times of magnifying glasses
Image of the caffeine in water, Fig. 3 is image of 10% basic components containing caffeine in water.From figures 2 and 3, it will be seen that
Free caffeine is inside and outside seen in threadiness in water, and solubility is unable to reach 10% in water, can only achieve 2%；And containing caffeine
Basic components, imaging is thinner in water, and the solubility in water is up to 10%.
In addition, with the addition of the anti-dandruff combination of safe and reasonable, dandruff quantity is reduced, the good battalion of bacteria breed is eliminated
Environment is supported, bacterium has lacked the possibility that scalp hair follicles produce inflammation.D-pantothenyl aleohol, vitamin A in nutrition composition rise to scalp, hair
Ventilative moist moisture film is formed to coordinative role, and in hair surface, it is ensured that the absorption of nutrition composition is in moisture film, with the time
Nutrient needed for the slow release scalp of passage, hair, really moist nutrition scalp, hair follicle cell, from depths give hair follicle,
Scalp is given pain taking care, and scientific nutrition combination is provided for hair healthy growth, adhere to using hair being made to keep fit, it is bright,
High resilience, strengthens the toughness of hair.
Further, the nutrition scalp hair follicles hair tonic elite, in percentage by weight, in addition to following components：
Perfume ingredient 0 ~ 0.50%.
Wherein, perfume ingredient is made up of essence and solubilizer polysorbate -20.The property of polysorbate -20 is gentle, has
Help make essence well mixed with each composition.
Further, the nutrition scalp hair follicles hair tonic elite, in percentage by weight, in addition to following components：
Perfume ingredient：Essence 0 ~ 0.10%；
Polysorbate -20 0 ~ 0.40%.
The preparation method of the nutrition scalp hair follicles hair tonic elite is also provided in the present invention, comprised the following steps：
Water and basic components are added in a kettle.（Glycerine, xanthan gum, carbomer sodium, EDTA-2Na, hydroxyethyl cellulose）, stir
Mix scattered, be heated to 75-85 degree, insulated and stirred 15-30 minutes starts cooling after all dissolving is scattered after solid formation；
Temperature adds nutrition composition when being down to 50 degree（Vitamin B3, allantoin, D-pantothenyl aleohol, vitamin A, biotin）And go
Consider component to be worth doing（Salicylic acid, Octopirox）, insulated and stirred 10-20 minutes makes it be uniformly dispersed, continues to cool；
Temperature adds energy component when being down to 45 degree（Caffeine, carnitine, arginine）, continue dispersed with stirring uniform；
Temperature sequentially adds perfume ingredient when being down to 40 degree（Essence+polysorbate -20）And preservative component（Phenoxyethanol,
Hexylene glycol, parahydroxyacet-ophenone）, and dispersed with stirring is uniform；
The moisture of polishing evaporation, stirs, filtering and discharging is produced.
Below by way of specific embodiment, the present invention will be further described.
Embodiment
According to the ingredient lists of table 1 below, the nutrition scalp hair follicles hair tonic elite of 4 not be the same as Examples is set, wherein, each raw material is equal
In terms of substance content 100%.
The preparation method of 4 embodiment scheme nutrition scalp hair follicles hair tonic elite is as follows：
Water and basic components are added in a kettle.（Glycerine, xanthan gum, carbomer sodium, EDTA-2Na, hydroxyethyl cellulose）, stir
Mix scattered, be heated to 75-85 degree, insulated and stirred 15-30 minutes starts cooling after all dissolving is scattered after solid formation；
Temperature adds nutrition composition when being down to 50 degree（Vitamin B3, allantoin, D-pantothenyl aleohol, vitamin A, biotin）And go
Consider component to be worth doing（Salicylic acid, Octopirox）, insulated and stirred 10-20 minutes makes it be uniformly dispersed, continues to cool；
Temperature adds energy component when being down to 45 degree（Caffeine, carnitine, arginine）, continue dispersed with stirring uniform；
Temperature sequentially adds perfume ingredient when being down to 40 degree（Essence+polysorbate -20）And preservative component（Phenoxyethanol,
Hexylene glycol, parahydroxyacet-ophenone）, and dispersed with stirring is uniform；
The moisture of polishing evaporation, stirs, filtering and discharging is produced.
Table 1
By the preparation-obtained nutrition scalp hair follicles hair tonic elite of embodiment 1-4 and comparative example（Common hair tonic elite on the market）
Using sensory evaluation method, the effect to each product carries out Integrated comparative：
100 exiguous human hairs or alopecia crowd is selected to be tested, by embodiment 1-4 and comparative example（Common hair growth tonic on the market
China）Used respectively to 100 subject's tests.Subject spreads nutrition scalp hair follicles hair tonic elite according to painting before hair washing, and comes
Return and rub massage 5-15 minutes, cleaned, can made if necessary with clear water after nutrition scalp hair follicles hair tonic elite all absorbs
Use shampoo（Product of the present invention is can be without cleaning, but is due to that product has sticky sense, and it can be washed with water）.Every kind of nutrition
Scalp hair follicles hair tonic elite continuously uses surrounding, and subject scores embodiment and comparative example according to the impression of oneself, commented
Divide using 5 points of systems, 1 point is worst, and 3 points are moderate, and 5 points are best, and the higher hair-growing effects of score are better.100 subjects make
It is 1-2 points with preceding scoring, it is as shown in table 2 using rear hair-growing effects evaluation result.
Table 2
Shown by the test result in table, after nutrition scalp hair follicles hair tonic elite of the present invention, remove dandruff and reduce inflammation
Disease problem obtains obvious control, and all subjects represent to like using nutrition scalp hair follicles hair tonic elite of the present invention,
And 80% subject can continue periodically to use after on probation.Use nutrition scalp hair follicles hair tonic elite of the present invention, natural on-off cycles of hair growth speed
Degree accelerates simultaneously have new hair longer, adheres to dramatically increasing using the dense degree of hair, moreover it is possible to show hair it is more glossy, rich in bullet
Property, toughness increase.
It should be appreciated that the application of the present invention is not limited to above-mentioned citing, for those of ordinary skills, can
To be improved or converted according to the above description, all these modifications and variations should all belong to the guarantor of appended claims of the present invention
Protect scope.
Claims (5)
1. a kind of nutrition scalp hair follicles hair tonic elite, it is characterised in that in percentage by weight, including following components：
Basic components 2 ~ 6%；
Nutrition composition 0.4-2.3%；
Energy component 0.55 ~ 2.8%；
Anti-dandruff component 0.3 ~ 0.7%；
Antiseptic ingredient 0 ~ 2.0%；
Water surplus；
Wherein, the basic components include glycerine, xanthan gum, carbomer sodium, EDTA-2Na, hydroxyethyl cellulose；Nutrition composition
Including vitamin B3, allantoin, D-pantothenyl aleohol, vitamin A, biotin；Energy bins point include caffeine, carnitine, arginine；Go
Considering component to be worth doing includes salicylic acid and Octopirox；Antiseptic ingredient includes Phenoxyethanol, hexylene glycol and parahydroxyacet-ophenone.
2. nutrition scalp hair follicles hair tonic elite according to claim 1, it is characterised in that the nutrition scalp hair follicles hair tonic
Elite, in percentage by weight, including following components：
Basic components：
Glycerine 1.3 ~ 3.63%；
EDTA-2Na 0.02~0.07%；
Carbomer sodium 0.38 ~ 1.5%；
Xanthan gum 0.1 ~ 0. 3%
Hydroxyethyl cellulose 0.2 ~ 0.5%；
Nutrition composition：
Vitamin B3 0.1 ~ 0.5%；
Allantoin 0.1 ~ 0.5%；
D-pantothenyl aleohol 0.1 ~ 0.7%；
Vitamin A 0.05 ~ 0.3%；
Biotin 0.05 ~ 0.3%；
Energy component：
Caffeine 0.3 ~ 1.5%；
Carnitine 0.05 ~ 0.5%；
Arginine 0.2 ~ 0.8%；
Anti-dandruff component：
Salicylic acid 0.1 ~ 0.3%；
Octopirox 0.2 ~ 0.4%；
Antiseptic ingredient：
Phenoxyethanol 0 ~ 0.5%；
Hexylene glycol 0 ~ 0.5%；
Parahydroxyacet-ophenone 0 ~ 0.5%；
Water：Surplus.
3. nutrition scalp hair follicles hair tonic elite according to claim 1, it is characterised in that the nutrition scalp hair follicles hair tonic
Elite, in percentage by weight, in addition to following components：
Perfume ingredient 0 ~ 0.50%；
Perfume ingredient includes essence and solubilizer polysorbate -20.
4. nutrition scalp hair follicles hair tonic elite according to claim 3, it is characterised in that the nutrition scalp hair follicles hair tonic
Elite, in percentage by weight, in addition to following components：
Perfume ingredient：Essence 0 ~ 0.10%；
Polysorbate -20 0 ~ 0.40%.
5. a kind of preparation method of nutrition scalp hair follicles hair tonic elite as described in claim 3 ~ 4 is any, it is characterised in that bag
Include following steps：
Water and basic components, dispersed with stirring are added in a kettle., 75-85 degree is heated to, and insulated and stirred 15-30 minutes treats solid
Phase thing starts cooling after all dissolving is scattered；
Temperature adds nutrition composition and anti-dandruff component, insulated and stirred 10-20 minutes when being down to 50 degree, makes it be uniformly dispersed, after
It is continuous to cool；
Temperature adds energy component when being down to 45 degree, continues dispersed with stirring uniform；
Temperature sequentially adds perfume ingredient and preservative component when being down to 40 degree, and dispersed with stirring is uniform；
The moisture of polishing evaporation, stirs, filtering and discharging is produced.
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| CN108578269A (en) * | 2018-02-01 | 2018-09-28 | 韩后化妆品股份有限公司 | Have effects that educate the composition of hair and Anti-hair loss, the preparation method of cosmetics, Essence and Essence |
| CN108904434A (en) * | 2018-08-18 | 2018-11-30 | 安徽国科生物科技有限公司 | A kind of stem cell hair growth stimulating shampoo and preparation method thereof |
| CN110123659A (en) * | 2019-05-29 | 2019-08-16 | 名臣健康用品股份有限公司 | A kind of Anti-hair loss composition and its in the application for preparing Anti-hair loss and washing in shield product |
| CN110882173A (en) * | 2019-12-05 | 2020-03-17 | 西北农林科技大学 | Formula of external daily chemical for preventing and treating alopecia by targeting hair follicle stem cells |
| CN111529465A (en) * | 2020-05-20 | 2020-08-14 | 南京夏悦贸易有限公司 | Wash-free hair loss prevention and hair growth nutrient solution and preparation method thereof |
| CN111643446A (en) * | 2020-07-30 | 2020-09-11 | 济南磐升生物技术有限公司 | Biological nutrition scalp hair follicle hair growth essence and preparation method thereof |
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