CN108553521A

CN108553521A - Radix Paeoniae Alba is fresh to carry spray-dried powders medicine materical crude slice

Info

Publication number: CN108553521A
Application number: CN201810733307.0A
Authority: CN
Inventors: 徐漫
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-09-21

Abstract

The invention discloses a kind of " Radix Paeoniae Alba is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that：White Peony Root harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, crush, be sieved after be vacuum-packed.The water content of powder decoction pieces is less than 10%.Such prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule etc., is conducive to carry, Clinical practice is convenient.

Description

Radix Paeoniae Alba is fresh to carry spray-dried powders medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of radix paeoniae alba decoction pieces.

Background technology

Chinese medicine Radix Paeoniae Alba is cohosh Chinese herbaceous peonyPaeonia lactifloraPall. dry root has blood-nourishing tune Through, astringing YIN to stop sweating, the effect of soft liver analgesic, suppressing liver-YANG.For blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, abdomen Bitterly, four limbs contraction pain, the treatment of dizziness of having a headache etc. are a herbs common on tcm clinical practice.The processing method of traditional Radix Paeoniae Alba is： It after medicinal material is excavated, cleans, removes end to end and radicula, set and boiled again after removing crust or peeling after being boiled in boiling water, dry, be packaged, Storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, be easy to by It is tide, mildew, infested, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy It is difficult to ensure, patient takes inconvenience, works slow.Therefore, develop that a kind of stable quality is reliable, storage/transportation is at low cost, is conducive to Keeping, carrying and easy to use, rapid-action novel radix paeoniae alba decoction pieces are imperative.Existing market radix paeoniae alba decoction pieces, in addition to tradition is drunk Except piece, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality It is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract water-soluble Property ingredient is fallen.

Invention content

The invention discloses a kind of " Radix Paeoniae Alba is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that：In white Peony Root It after harvesting, cleans in time, impurity and the dis-medicinal part such as removal silt are cleaned in taking advantage of using fresh herb tap water in 24 hours, scraped off outer Skin, and it is cut into the piece of 2 ~ 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, immersion and constantly stirring 5 ~ 30 minutes, filtering, dregs pressing took juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction, boils 10 ~ 30 minutes, while hot mistake Filter, the dregs of a decoction are squeezed the juice again, collect concoction.Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, dense It is reduced to the concentrate that relative density is 1.02 ~ 1.10.The concentrate of gained is spray-dried, control dried object water content is 10% Within, it crushes, crosses 60 mesh sieve, be vacuum-packed to get finished product.Finished product medicine materical crude slice contains Paeoniflorin（C₂₃H₂₈O₁₁) 3.0% must not be less than.This The clinical general usage amount of powder decoction pieces is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, also can directly enter pill, powder, capsule and In tablet, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.

The present invention solve traditional radix paeoniae alba decoction pieces are bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after white Peony Root is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and scrapes off crust, and be cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, mistake Filter, dregs pressing take juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, The dregs of a decoction are squeezed the juice again, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and being concentrated into relative density is 1.05.The concentrate of gained is spray-dried, until water content is 10%, is crushed, 60 mesh sieve is crossed, is vacuum-packed to get finished product.At Product medicine materical crude slice contains Paeoniflorin（C₂₃H₂₈O₁₁) it is 3.8%.

Claims

1. a kind of Radix Paeoniae Alba is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that：After white Peony Root harvesting, clean in time, Impurity and the dis-medicinal parts such as silt are removed, is cleaned in taking advantage of using fresh herb tap water in 12 hours, crust is scraped off and is cut into 2 ~ 5mm thickness The water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added in piece, impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice；The gained dregs of a decoction In add the water of 5 ~ 10 times of weight, boil 10 ~ 30 minutes, filter while hot, the dregs of a decoction are squeezed the juice again, collect concoction；Merge above-mentioned Concoction is crossed 60 ~ 100 mesh sieve, is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；Gained concentrate Spray drying, control dried object water content are to be crushed within 10%, cross 60 mesh sieve, are vacuum-packed to get finished product；Finished product medicine materical crude slice contains Paeoniflorin（C₂₃H₂₈O₁₁) 3.0% must not be less than.

2. Radix Paeoniae Alba according to claim 1 is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, and such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.