CN108553402A - A kind of fresh and alive U.S. flesh water light Essence - Google Patents
A kind of fresh and alive U.S. flesh water light Essence Download PDFInfo
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- CN108553402A CN108553402A CN201810159349.8A CN201810159349A CN108553402A CN 108553402 A CN108553402 A CN 108553402A CN 201810159349 A CN201810159349 A CN 201810159349A CN 108553402 A CN108553402 A CN 108553402A
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- hyaluronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of fresh and alive U.S. flesh water light Essences, feature is by volume including mescenchymal stem cell extracting solution 20 30%, hyaluronic acid 15 20%, trehalose moisturizing factor 10 15%, expense dish extracting solution 10 15%, glycerine 1 3%, butanediol 1 3% and lactic acid 1 3%, surplus is deionized water, wherein mescenchymal stem cell extracting solution is obtained by umbilical cord mesenchymal stem cells are broken, and hyaluronic acid presses mass volume ratio 2 by polymer hyaluronic acid and low molecular weight hyaluronic acid：1 mixes, advantage be skin can be made to change bright, water is tender, elastic, careful and preservative free.
Description
Technical field
The present invention relates to skin care item, more particularly, to a kind of fresh and alive U.S. flesh water light Essence.
Background technology
Skin is the maximum organ of human body, and the 5%-15% of total weight percentage of liveweight, skin covering whole body, it makes various in vivo
Tissue and organ are from physical, mechanicalness, chemically with the invasion of pathogenic microorganism, and there are two aspects for skin tool
On the one hand barrier action prevents internal water, the loss of electrolyte and other substances from the other hand organizing extraneous harmful substance
Intrusion, keeps the stabilization of human internal environment, is physiologically playing important defencive function, while skin also assists in the metabolism of human body
Process.
With advancing age, metabolism can change the function and appearance of skin naturally.Sunlight can provide warm
Feeling and so that skin is showed the gloss of bodybuilding, but be constantly exposed under sunlight, the ultraviolet light in sunlight is enough to make skin
Drying and dehydrating comes to harm, and wrinkle occurs.Dry and low temperature environment can accelerate the loss of moisture of skin, and skin is made to feel
It is dry and tight；Moist, high temperature environment then can make the sweat gland secretion of skin vigorous, cause skin greasing.Environmental pollution is serious,
Pollutant in air can be attached to skin surface, and pore is made to block, and lead to skin water shortage, relaxation, obscure, sensitive, grease point
Unbalance, aging is secreted, can also bring blackhead, the problems such as pore is coarse, in addition to this, urban life pressure, but also dry skin
Relaxation, tarnishes, colour of skin diseased shape, to accelerate skin aging, interfere skin health；Simultaneously fatigue, stay up late, with year
The growth in age and skin resistance declines, can all make skin be easy, by external invasion, to cause allergy, dimness, drying, relaxation etc.
Problem.Therefore, above-mentioned various skin problems annoying always numerous people seeking beauties.
Everybody has a love of beauty, and to not only wanting for the beautiful modern female for also wanting health, beauty and skin care is no longer year
The slogan of light women, but really implement in practice.But as the pollution of environment and the pollution of diet, people are passive
The many toxin of inspiration, for body and appearance, the Ms that likes to be beautiful usually takes some beauty and skin care drugs, but in the market this
Drug price is expensive, and rich in supplementary elements such as additive, preservatives, takes for a long time, can be caused to people's physical and mental health very big
Injury.People coat skin care item on the skin, reduce injury of the beauty and skin care drug to body, but with external environment
Constantly deteriorate, the decline of air quality, a large amount of uses of various chemical toilets bring numerous wounds to our skin
Evil, becomes coarse generation spot.Therefore various cosmetics are following, but these cosmetics only hide in appearance mostly
It covers, the situation of improvement skin that can not be profound.
Invention content
Technical problem to be solved by the invention is to provide it is a kind of can make skin change bright, water is tender, it is elastic, careful and
The fresh and alive U.S. flesh water light Essence of preservative free.
Technical solution is used by the present invention solves above-mentioned technical problem：A kind of fresh and alive U.S. flesh water light Essence, by body
Accumulating ratio includes：Mescenchymal stem cell extracting solution 20-30%, hyaluronic acid 15-20%, trehalose moisturizing factor 10-15%, Fei Caiti
It is deionized water to take liquid 10-15%, glycerine 1-3%, butanediol 1-3% and lactic acid 1-3%, surplus.
The human mesenchymal stem cell extraction liquid and preparation method thereof is as follows：
（1）Cell is collected
By all detections umbilical cord mesenchymal stem cells culture solution pipette of qualification and the cell generation no more than 10 times
Suction discards, and after cleaning culture bottle 2-3 times with a small amount of physiological saline, the trypsin solution that mass concentration is 0.25% is added and disappears
Change, and observe the variation of cellular morphology under the microscope, when cell starts de- wall when part, it is whole that 10-20mL physiological saline is added
It only digests, gently bottom of bottle cell is swept or is gently blown and beaten with pipette and allows the completely de- wall of cell with cell scraper；It then will be thin
Born of the same parents' suspension is transferred in centrifuge tube, is centrifuged 10 minutes in 1000rpm, is abandoned supernatant, adding 10mL physiological saline fully to blow and beat mixing makes
Cell is resuspended, and after repeated centrifugation abandons supernatant 2 times, cell is suspended with sterilized water for injection and is dispensed to cryopreservation tube；
（2）The cracking of mescenchymal stem cell
Cryopreservation tube is placed in liquid nitrogen container to freeze and is transferred to water-bath 10 minutes, multigelation 3 in 37 DEG C of water-baths immediately after ten minutes
After secondary；Liquid in cryopreservation tube is gone in sterile EP tube, is centrifuged 30 minutes in 10000rpm, gained supernatant Bomaili A is determined
Hold, 0.22 μm of filter filtering, gained supernatant is mescenchymal stem cell extracting solution, is sucted clearly to cillin bottle with micropipette rifle
In, sterilized serum cap is then gripped with aseptic nipper, bottle cap is good, and left hand buttresses cillin bottle with overturning-preventing, uses capping machine
It by bottle closure, is frozen in -20 DEG C of refrigerators, wherein the cell concentration of mescenchymal stem cell extracting solution is 5*106/2ml.
The hyaluronic acid presses mass volume ratio 2 by polymer hyaluronic acid and low molecular weight hyaluronic acid：1 mixing and
At.
It is described that take dish extraction liquid and preparation method thereof as follows：Take medication after dish is dried 24~36 hours in 70~80 DEG C by fresh
It is crushed with pulverizer and crosses 80 mesh and sieve to obtain expense vegetable powder, vegetable powder will be taken with 10% ethanol solution by solid-liquid ratio 1：50 ratio mixing
Afterwards, it is extracted 4~5 hours at 50~60 DEG C, then under 3000r/min rotating speeds after centrifugation 10min, after taking supernatant to be filtered by vacuum
Obtain the expense dish extracting solution rich in flavones.
Compared with the prior art, the advantages of the present invention are as follows：A kind of fresh and alive U.S. flesh water light Essence of the invention, by volume
Including：Mescenchymal stem cell extracting solution 20-30%, hyaluronic acid 10-15%, trehalose moisturizing factor 8-10%, take dish extracting solution 8-
10%, glycerine 1-3%, butanediol 1-3% and lactic acid 1-3%, surplus are deionized water, wherein the effect of mescenchymal stem cell extracting solution
Be repair, activation Skin Cell, provide nutriment for skin, can destratum corneum, highlight；Macromolecular hyaluronic acid can will carry
It takes liquid lock in skin, is unlikely to be lost at once after importing, micromolecule hyaluronic acid moistening effect is fine；Trehalose can be effectively
Protect epidermal cell membrane structure, activating cell, improve skin, enable skin health natural, flexible, trehalose high temperature, it is high and cold,
One layer of special protective film can be formed in cell surface under the environment such as drying, intensive ultraviolet radiation, keep the original nutrition of skin
And moisture, skin sunburn and melanin deposition are avoided, skin ageing phenomenon is effective against；The flavones tool contained in expense dish extracting solution
There are certain bacteriostasis and antioxidation, can effectively prevent Essence and corroded by bacterium and spoilage organisms, improves
Shelf life, and it effectively prevent the oxidation deteriorations such as mescenchymal stem cell.
In conclusion a kind of fresh and alive U.S. flesh water light Essence of the present invention, can show after using it for face smearing or injection
Writing improves a variety of skin problems such as drying, microgroove, aging, and help skin improves water humidity, restores elasticity, regeneration, activates, is thin
Greasy, whitening, anti-ageing, antioxygen etc. make skin restore more young healthy state.
Specific implementation mode
Present invention is further described in detail with reference to embodiments.
One, specific embodiment
Embodiment 1
A kind of fresh and alive U.S. flesh water light Essence includes by volume：Mescenchymal stem cell extracting solution 25%, hyaluronic acid 17%, seaweed
Sugared moisturizing factor 12% takes dish extracting solution 13%, glycerine 2%, butanediol 2% and lactic acid 2%, and surplus is deionized water.Wherein the human world is filled
It is as follows that matter stem cell extracts liquid and preparation method thereof：
（1）Cell is collected
By all detections umbilical cord mesenchymal stem cells culture solution of qualification and the cell generation no more than 10 times（It is raw from hat sky
Object is bought）It is discarded with pipette suction, after clean culture bottle 2-3 time with a small amount of physiological saline, addition mass concentration is 0.25%
Trypsin solution digests, and observes the variation of cellular morphology under the microscope, and when cell starts de- wall when part, 10- is added
20mL physiological saline terminates digestion, gently sweeps bottom of bottle cell with cell scraper or is gently blown and beaten with pipette and make cell complete
De- wall；Then cell suspension is transferred in centrifuge tube, is centrifuged 10 minutes in 1000rpm, abandons supernatant, add 10mL physiological saline
Fully piping and druming mixing makes cell be resuspended, and after repeated centrifugation abandons supernatant 2 times, cell is suspended with sterilized water for injection and is dispensed to jelly
Deposit pipe；
（2）The cracking of mescenchymal stem cell
Cryopreservation tube is placed in liquid nitrogen container to freeze and is transferred to water-bath 10 minutes, multigelation 3 in 37 DEG C of water-baths immediately after ten minutes
After secondary；Liquid in cryopreservation tube is gone in sterile EP tube, is centrifuged 30 minutes in 10000rpm, gained supernatant Bomaili A is determined
Hold, 0.22 μm of filter filtering, gained supernatant is mescenchymal stem cell extracting solution, is sucted clearly to cillin bottle with micropipette rifle
In, sterilized serum cap is then gripped with aseptic nipper, bottle cap is good, and left hand buttresses cillin bottle with overturning-preventing, uses capping machine
It by bottle closure, is frozen in -20 DEG C of refrigerators, wherein the cell concentration of mescenchymal stem cell extracting solution is 5*106/2ml.
Hyaluronic acid presses mass volume ratio 2 by polymer hyaluronic acid and low molecular weight hyaluronic acid：1 mixes.
It is as follows to take dish extraction liquid and preparation method thereof：Take fresh after dish is dried 24~36 hours in 70~80 DEG C with medicinal crushing
Machine crushes and crosses 80 mesh and sieves to obtain expense vegetable powder, will take vegetable powder with 10% ethanol solution by solid-liquid ratio 1：After 50 ratio mixing, 50
It is extracted 4~5 hours at~60 DEG C, then richness is obtained after taking supernatant to be filtered by vacuum after centrifugation 10min under 3000r/min rotating speeds
Take dish extracting solution containing flavones.
Embodiment 2
With above-described embodiment 1, difference lies in：It is fresh and alive U.S. flesh water light Essence include by volume：Mescenchymal stem cell extracts
Liquid 30%, trehalose moisturizing factor 15%, takes dish extracting solution 15%, glycerine 3%, butanediol 3% and lactic acid 3% at hyaluronic acid 20%, remaining
Amount is deionized water.
Embodiment 3
With above-described embodiment 1, difference lies in：It is fresh and alive U.S. flesh water light Essence include mescenchymal stem cell extracting solution 20%, it is transparent
Matter acid 15%, trehalose moisturizing factor 10% take dish extracting solution 10%, glycerine 1%, butanediol 1% and lactic acid 1%, and surplus is deionization
Water.
Two, contrast test
By fresh and alive U.S. flesh water light essence liquid product obtained in example 1 to example 3, clinical trial comparison is carried out with blank group, is faced
Bed experiment condition be：40 women of volunteer, are divided into 4 groups at age 20-45 Sui, every group of 10 people, use respectively product 1,2,3 with
And the blank group without using product, product are respectively used 1 time, are used continuously 60 days, application method sooner or later daily：After cleaning skin,
It takes and is applied to position needed for face or other bodies in right amount, from inside to outside, from the top down gently until massage skin to absorption.
Shown in experimental result the following table 1：
Table 1
In conclusion the fresh and alive U.S.'s flesh water light Essence of the present invention can help skin to improve water humidity, restore elasticity, regeneration, live
Change, exquisiteness, whitening, anti-ageing, antioxygen etc. make skin restore more young healthy state.
Above description is not limitation of the present invention, and the present invention is also not limited to the example above.The art it is common
Technical staff is in the essential scope of the present invention, the variations, modifications, additions or substitutions made, and should also belong to the protection of the present invention
Range.
Claims (4)
1. a kind of fresh and alive U.S. flesh water light Essence, it is characterised in that include by volume：Mescenchymal stem cell extracting solution 20-30%,
Hyaluronic acid 15-20%, trehalose moisturizing factor 10-15%, take dish extracting solution 10-15%, glycerine 1-3%, butanediol 1-3% and breast
Sour 1-3%, surplus are deionized water.
2. the fresh and alive U.S. flesh water light Essence of one kind according to claim 1, it is characterised in that the human mesenchyme is dry thin
It is as follows that born of the same parents extract liquid and preparation method thereof：
（1）Cell is collected
By all detections umbilical cord mesenchymal stem cells culture solution pipette of qualification and the cell generation no more than 10 times
Suction discards, and after cleaning culture bottle 2-3 times with a small amount of physiological saline, the trypsin solution that mass concentration is 0.25% is added and disappears
Change, and observe the variation of cellular morphology under the microscope, when cell starts de- wall when part, it is whole that 10-20mL physiological saline is added
It only digests, gently bottom of bottle cell is swept or is gently blown and beaten with pipette and allows the completely de- wall of cell with cell scraper；It then will be thin
Born of the same parents' suspension is transferred in centrifuge tube, is centrifuged 10 minutes in 1000rpm, is abandoned supernatant, adding 10mL physiological saline fully to blow and beat mixing makes
Cell is resuspended, and after repeated centrifugation abandons supernatant 2 times, cell is suspended with sterilized water for injection and is dispensed to cryopreservation tube；
（2）The cracking of mescenchymal stem cell
Cryopreservation tube is placed in liquid nitrogen container to freeze and is transferred to water-bath 10 minutes, multigelation 3 in 37 DEG C of water-baths immediately after ten minutes
After secondary；Liquid in cryopreservation tube is gone in sterile EP tube, is centrifuged 30 minutes in 10000rpm, gained supernatant Bomaili A is determined
Hold, 0.22 μm of filter filtering, gained supernatant is mescenchymal stem cell extracting solution, is sucted clearly to cillin bottle with micropipette rifle
In, sterilized serum cap is then gripped with aseptic nipper, bottle cap is good, and left hand buttresses cillin bottle with overturning-preventing, uses capping machine
It by bottle closure, is frozen in -20 DEG C of refrigerators, wherein the cell concentration of mescenchymal stem cell extracting solution is 5*106/2ml.
3. the fresh and alive U.S. flesh water light Essence of one kind according to claim 1, it is characterised in that：The hyaluronic acid is by height
Molecular weight hyaluronic acid and low molecular weight hyaluronic acid press mass volume ratio 2：1 mixes.
4. the fresh and alive U.S. flesh water light Essence of one kind according to claim 1, it is characterised in that described takes dish extracting solution system
Preparation Method is as follows：It is crushed with medicinal pulverizer after fresh expense dish is dried 24~36 hours in 70~80 DEG C and crosses 80 mesh and sieve to obtain
Take vegetable powder, vegetable powder will be taken with 10% ethanol solution by solid-liquid ratio 1：After 50 ratio mixing, it is small that 4~5 are extracted at 50~60 DEG C
When, then the expense dish extracting solution rich in flavones is obtained after taking supernatant to be filtered by vacuum after centrifugation 10min under 3000r/min rotating speeds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810159349.8A CN108553402A (en) | 2018-02-26 | 2018-02-26 | A kind of fresh and alive U.S. flesh water light Essence |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810159349.8A CN108553402A (en) | 2018-02-26 | 2018-02-26 | A kind of fresh and alive U.S. flesh water light Essence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108553402A true CN108553402A (en) | 2018-09-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810159349.8A Pending CN108553402A (en) | 2018-02-26 | 2018-02-26 | A kind of fresh and alive U.S. flesh water light Essence |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111000755A (en) * | 2020-01-07 | 2020-04-14 | 北京沐恩瑞生物科技有限公司 | Method for enhancing moisturizing effect of hyaluronic acid |
| CN112842986A (en) * | 2021-02-24 | 2021-05-28 | 山东新佰利生物技术有限公司 | Essence without preservative and preparation method thereof |
| CN113041206A (en) * | 2019-12-11 | 2021-06-29 | 春日花开生物科技(深圳)有限公司 | Essence containing mesenchymal stem cell factor and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596243A (en) * | 2014-11-20 | 2016-05-25 | 龚䶮 | Essence liquid containing nano-gold and thermal spring water and mask |
| CN106137881A (en) * | 2016-08-29 | 2016-11-23 | 秦艳红 | A kind of essence |
-
2018
- 2018-02-26 CN CN201810159349.8A patent/CN108553402A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596243A (en) * | 2014-11-20 | 2016-05-25 | 龚䶮 | Essence liquid containing nano-gold and thermal spring water and mask |
| CN106137881A (en) * | 2016-08-29 | 2016-11-23 | 秦艳红 | A kind of essence |
Non-Patent Citations (3)
| Title |
|---|
| 国家食品药品监督管理总局 批准颁布: "化妆品禁限用组分", 《化妆品安全技术规范(2015版）》 * |
| 宝拉-培冈（美）: "《带着我去化妆品柜台》", 31 December 2015, 新世界出版社 * |
| 马振友 等: "《皮肤美容化妆品制剂手册》", 31 March 2004, 中医古籍出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113041206A (en) * | 2019-12-11 | 2021-06-29 | 春日花开生物科技(深圳)有限公司 | Essence containing mesenchymal stem cell factor and preparation method thereof |
| CN111000755A (en) * | 2020-01-07 | 2020-04-14 | 北京沐恩瑞生物科技有限公司 | Method for enhancing moisturizing effect of hyaluronic acid |
| CN112842986A (en) * | 2021-02-24 | 2021-05-28 | 山东新佰利生物技术有限公司 | Essence without preservative and preparation method thereof |
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