CN108531341A - A kind of health-care spirit and preparation method thereof for having effects that auxiliary and alleviating gout - Google Patents
A kind of health-care spirit and preparation method thereof for having effects that auxiliary and alleviating gout Download PDFInfo
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a kind of health-care spirit and preparation method thereof for having effects that auxiliary and alleviating gout, the health-care spirit is made of the raw material containing following weight in every 100KL white wine：8~12kg of Rhizoma Smilacis Glabrae extract, 3~5kg of dandelion extract, 3~5kg of kudzu root extract, 3~5kg of honeysuckle or chrysanthemum extract；Preparation method is：First be sequentially prepared out Rhizoma Smilacis Glabrae extract, dandelion extract, kudzu root extract, Honegsukle flower P.E, chrysanthemum extract, then each extract be added in high quality liquor by formula rate, stirs, stand 48 hours, filtering, it is filling to get；The present invention's has effects that auxiliary alleviates the health-care spirit of gout, and the limpid micro- Huang of wine and women-sensual pursuits, the fragrant fragrance of medicine, wine body is soft, sweet tasty and refreshing, and Zhu Xiang coordinates, and aftertaste is refreshing net；Be especially suitable for often attend the personage that occasion is entertained in various commercial affairs, be one kind can meet commercial affairs drink demand and auxiliary alleviation gout alcohol product.
Description
Technical field
The present invention relates to a kind of health-care spirit, especially a kind of health-care spirit and its system for having effects that auxiliary and alleviating gout
Preparation Method.
Background technology
Gout is that long-term disorders of purine metabolism, blood uric acid increase caused disease.Purine is widely present in various foods,
Metabolism through human body generates uric acid.If the uric acid that for some reason, human body generates is excessive or excludes very few, delay
Uric acid in blood will increase, and a series of gout symptoms occur.The uric acid in blood of patient with gout is excessive, uric acid crystal meeting
In site depositions such as joint, kidney, hearts, cause the damage of these tissues and organ.
One of most important pathogenic factors of gout is overnutrition.Most of patient with gout have high heat, high protein, high in fat
The eating habit of fat.Gout medically can not also cure at present, general to select drug to the ill or take operative treatment.Common medicine
Object has colchicin, anti-inflammation analgesia medicine, uricosureic agent and inhibits several classes such as uric acid synthetic drug, but also has certain side effect.
Since alcohol can influence uric acid synthesis and metabolism through a variety of ways, therefore drink always as the taboo of goat
Avoid, and at home and abroad the gout practice guidelines of multiple versions explicitly point out：Patient with gout strictly guards against the various drinks of drink, and very much
Patient is hyperuricemia, gout to be suffered from because of excessive consumption of alcohol, but rarely patient can stringent abstinence from alcohol.Many patients are because of work
The many factors such as work, communication, living habit are drunk often, and also some patientss are liked and drink, are addicted to drink usually, therefore, research and development
It is a that there is the health liquor for slowing down uric acid raising, reducing gout seizure frequency function, it can targetedly meet this partial mass
Health care demand.
It there is no the precedent using vina anti-trioxypurine both at home and abroad.Traditional Chinese medicine is alleviated into gout, the theory of anti-trioxypurine, puts into practice essence
Expressed in the form of vina, meet suffer from gout but have drink, be addicted to drink demand crowd the needs of, be one piece of health product neck
The blank that domain is not yet opened up.Therefore, it draws traditional Chinese medicine ancient Chinese medicine doctor and treats gout experience, while using tcm components theory and side
Method, excavation, which has been provided, inhibits uric acid synthesis, promotes uric acid excretion, has the group of certain reducing blood lipid and protect liver, shield kidney effect concurrently
Side, function factor, and a health-care spirit for having and alleviating gout function is developed, it is practicable.And for having to
The personage that occasion is entertained in various commercial affairs is often attended, since diet time extends, the easily excessive hyperglycemia, high protein, high in fat of drinking
The food of fat, high cholesterol is more easy to overnutrition, and unavoidable the problem of drinking.If can suffer from specifically for gout
Person provides the alcohol product that one kind can meet commercial requiring alcohol consumption and auxiliary alleviates gout, will be welcome by market.
Invention content
The purpose of the present invention is just specific to current many patient with gout because of various aspects such as work, communication, living habits
Factor, which takes, often drinks, and also some patientss like the problems such as drinking, being addicted to drink usually, and there is the one kind provided auxiliary to alleviate pain
The health-care spirit and preparation method thereof of wind effect, health-care spirit of the present invention, which has, to be slowed down uric acid raising, reduces gout seizure frequency
The effect of.
A kind of health-care spirit for having effects that auxiliary and alleviating gout of the present invention, often contains following weight in 100KL white wine
Raw material：
3~5kg of Rhizoma Smilacis Glabrae extract 8~12kg dandelion extracts
3~5kg of 3~5kg of kudzu root extract honeysuckles or chrysanthemum extract.
A kind of health-care spirit for having effects that auxiliary and alleviating gout of the present invention, optimization formula is per in 100KL white wine
Raw material containing following weight：
Rhizoma Smilacis Glabrae extract 10kg dandelion extracts 4kg
Kudzu root extract 4kg Honegsukle flower P.Es 4kg.
A kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout of the present invention, includes the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 10~14h, Extracting temperature 60
DEG C~80 DEG C, it flows back 2.5~3.5 hours, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid is dense
Contraction be spray-dried or be dried in vacuo at medicinal extract to get；The solvent dosage is the matter of 20 times of amounts of smilax quality
Measure the ethanol solution that score is 50%；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 60 DEG C~80 DEG C, is returned
Extracting solution is crossed the ultrafiltration membrane of macromolecule by stream 1.5~2.5 hours, filtering, collects trapped fluid, and medicinal extract is made in trapped fluid concentration
Be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 10 times of amounts of dandelion quality is 45%
Ethanol solution；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 8~12 hours, and Extracting temperature is 70 DEG C
It~80 DEG C, flows back 2.5~3.5 hours, filtering isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 1.5~2.5
Hour, filtering merges extracting solution twice, and extracting solution is crossed to the ultrafiltration membrane of macromolecule, collects trapped fluid, and trapped fluid concentration is made
Medicinal extract be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 15 times of amounts of pueraria lobata quality is
50% ethanol solution；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 50 DEG C~70 DEG C, is returned
Extracting solution is crossed the ultrafiltration membrane of macromolecule by stream 3.5~4.5 hours, filtering, collects trapped fluid, and medicinal extract is made in trapped fluid concentration
Be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%
Ethanol solution；
（5）The preparation of chrysanthemum extract：Chrysanthemum and solvent are added into extractor, Extracting temperature is 50 DEG C~70 DEG C, reflux 30
~60 minutes, filtering isolated the dregs of a decoction, solvent is added heating extraction 30-60 minutes again in the dregs of a decoction, and filtering, merging carries twice
Take liquid, extracting solution crossed to the ultrafiltration membrane of macromolecule, collect trapped fluid, trapped fluid concentration be made medicinal extract carry out spray drying or
Vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 12 times of amounts of quality of Flos Lonicerae is 80%；
（6）The preparation of health-care spirit：Choose high quality liquor 100KL, added respectively by formula rate thereto Rhizoma Smilacis Glabrae extract,
Dandelion extract, kudzu root extract, Honegsukle flower P.E or chrysanthemum extract stir after the completion of addition, stand
48 hours, filtering, the filling alcoholic drink transparent to get micro- Huang.
A kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout of the present invention, includes the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 12h, Extracting temperature is 70 DEG C,
Extracting solution is crossed the ultrafiltration membrane of macromolecule by reflux 3 hours, filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is sprayed
Mist is dry or vacuum drying to get；The solvent dosage is the ethyl alcohol that the mass fraction of 20 times of amounts of smilax quality is 50%
Solution；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 70 DEG C, and reflux 2 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 10 times of amounts of dandelion quality is 45%；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 10 hours, and Extracting temperature is 75 DEG C and returns
Stream 3 hours, filtering, isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 2 hours, filters, and merging is extracted twice
Extracting solution is crossed the ultrafiltration membrane of macromolecule by liquid, collects trapped fluid, and trapped fluid concentration is made medicinal extract and carries out spray drying or true
Sky it is dry to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of pueraria lobata quality is 50%；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 60 DEG C, and reflux 4 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%；
（5）The preparation of health-care spirit：High quality liquor 100KL is chosen, is separately added into Rhizoma Smilacis Glabrae extract 10kg, dandelion thereto
Extract 4kg, kudzu root extract 4kg, Honegsukle flower P.E 4kg are stirred after the completion of addition, stand 48 hours, mistake
Filter, the filling alcoholic drink transparent to get micro- Huang.
Heretofore described white wine is delicate fragrance type, Luzhou-flavor or Maotai-flavor liquor.Can according to the mouthfeel demand of consumer,
The specific high quality liquor for selecting the different flavors such as delicate fragrance type, Luzhou-flavor, Maotai-flavor extracts object alcohol extracting, to obtain different perfume (or spice)
The alcoholic drink of type, different flavor, different quality class.
Traditional Chinese medicine thinks that the etiology and pathogenesis of gout is mainly that body is affected by the cold in deficiency of qi and blood, imbalance of yin and yang
Damp and hot heresy, with the passing of time phlegm-turbidity and blood stasis blood are mutually tied, numbness resistance channels and collaterals, blood vessels and cause, treatment is when with heat-clearing dredging collateral, and removing toxic substances dehumidifying is wants.
Selected smilax is sweet in flavor, mild-natured in above-mentioned formula, has dehumidifying, and removing toxic substances is easing joint movement and other effects,《Detailed outline》
It carries：" strengthening the spleen and stomach, strengthening the bones and muscles, curing rheumatism, sharp joint, stopping leak rush down.Control contraction ostalgia, malignant sore carbuncle swells.Solve mercury powder, vermilion poison "；Pu
Public English is bitter, sweet, cold, Return liver, stomach, clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia,《Herbal justice》：" dandelion, property are clear
It is cool, control all and treat sore, large carbuncle, all cards of red and swollen heat toxin "；Pueraria lobata is sweet, pungent, cool, and returns spleen, stomach, expelling pathogenic factors from muscles and skin are brought down a fever, and are promoted the production of body fluid, promoting eruption, rises
Positive antidiarrheal,《Detailed outline》：" scattered stagnated fire "；Honeysuckle is sweet, cold, return lung, the heart, stomach, clearing heat and detoxicating, wind-heat dissipating,《Chongqing hall with
Pen》：" clear network apoplexy fire is damp and hot, solves the warm dirty filthy heresy of epidemic disease, the floating more wind sun of breath liver and gall, controls convulsion and faints all diseases of epilepsy "；Or with chrysanthemum,
It is sweet, bitter, it is slightly cold, relieve heat heat-clearing, flat liver improving eyesight,《Japan hanako materia medica》：" sharp blood vessels control four limbs urticaria ".Full side's heat-clearing dredging collateral, solution
Poison dehumidifying, curative effect can the phase.Smilax is monarch in side, and dandelion, pueraria lobata are minister, and honeysuckle or chrysanthemum are adjuvant, and four traditional Chinese medicine is total
With collaboration, play the role of reduction uric acid level, alleviates gout symptom.
The health-care spirit of the present invention is that each component is first extracted extract by selection when preparing, and effective content is high, lightly seasoned,
Color is shallow, and suitable exploitation can reduce uric acid level, alleviates gout health care white wine.Ingredients is taken from integration of drinking and medicinal herbs medicine in prescription
Material and health food catalogue medicinal material securely and reliably meet relevant laws and regulations requirement.
Compared with prior art, the present invention advantage is as follows：
1. the alcoholic drink obtained by adding Rhizoma Smilacis Glabrae extract, dandelion extract etc. into high quality liquor, does not influence wine body
Mouthfeel, and functional component is preferably preserved；
2. the health-care spirit research that auxiliary alleviates gout still belongs to the flavor for not only having had traditional liquor for the first time, mouthfeel, but also with auxiliary
The function of helping and reduce uric acid in blood, prevent gout relapse indications.
The present invention's has effects that auxiliary alleviates the health-care spirit of gout, and the limpid micro- Huang of wine and women-sensual pursuits, medicine is fragrant fragrant, and wine body is soft
With sweet tasty and refreshing, Zhu Xiang coordinates, and aftertaste is refreshing net；It is especially suitable for often attending the personage that occasion is entertained in various commercial affairs, has and slow down
Uric acid increase, reduce gout seizure frequency the effect of, be one kind can meet commercial affairs drink demand and auxiliary alleviation gout
The alcohol product of shape.
Specific implementation mode
Embodiment 1
A kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout, includes the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 12h, Extracting temperature is 70 DEG C,
Extracting solution is crossed the ultrafiltration membrane of macromolecule by reflux 3 hours, filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is sprayed
Mist is dry or vacuum drying to get；The solvent dosage is the ethyl alcohol that the mass fraction of 20 times of amounts of smilax quality is 50%
Solution；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 70 DEG C, and reflux 2 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 10 times of amounts of dandelion quality is 45%；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 10 hours, and Extracting temperature is 75 DEG C and returns
Stream 3 hours, filtering, isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 2 hours, filters, and merging is extracted twice
Extracting solution is crossed the ultrafiltration membrane of macromolecule by liquid, collects trapped fluid, and trapped fluid concentration is made medicinal extract and carries out spray drying or true
Sky it is dry to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of pueraria lobata quality is 50%；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 60 DEG C, and reflux 4 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%；
（5）The preparation of health-care spirit：Choose high-quality aromatic Chinese spirit 100KL, be separately added into thereto Rhizoma Smilacis Glabrae extract 10kg,
Dandelion extract 4kg, kudzu root extract 4kg, Honegsukle flower P.E 4kg are stirred after the completion of addition, and it is small to stand 48
When, filtering, the filling alcoholic drink transparent to get micro- Huang.
Experiment proves that the lower health-care spirit obtained of the preparation process and formula of the present embodiment, effect and flavor are most
It is good.
Embodiment 2
A kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout, includes the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 10h, Extracting temperature is 80 DEG C,
Extracting solution is crossed the ultrafiltration membrane of macromolecule by reflux 2.5 hours, filtering, collects trapped fluid, and medicinal extract progress is made in trapped fluid concentration
Spray drying or be dried in vacuo to get；The solvent dosage is the second that the mass fraction of 20 times of amounts of smilax quality is 50%
Alcoholic solution；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 60 DEG C, and reflux 2.5 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 10 times of amounts of dandelion quality is 45%；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 12 hours, and Extracting temperature is 70 DEG C and returns
Stream 3.5 hours, filtering, isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 2.5 hours, filters, and merging carries twice
Take liquid, extracting solution crossed to the ultrafiltration membrane of macromolecule, collect trapped fluid, trapped fluid concentration be made medicinal extract carry out spray drying or
Vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of pueraria lobata quality is 50%；
（4）The preparation of chrysanthemum extract：Honeysuckle and solvent are added into extractor, Extracting temperature is 70 DEG C, is flowed back 30 minutes,
Filtering, isolates the dregs of a decoction, solvent is added again in the dregs of a decoction is heated to 50 DEG C and flow back 1 hour, and filtering merges extracting solution twice,
Extracting solution is crossed to the ultrafiltration membrane of macromolecule, collects trapped fluid, trapped fluid concentration is made medicinal extract and carries out spray drying or vacuum
It is dry to get；The solvent dosage is the ethanol solution that the mass fraction of 12 times of amounts of quality of Flos Lonicerae is 80%；
（5）The preparation of health-care spirit：Choose high-quality fen-flavor type white spirit 100KL, be separately added into thereto Rhizoma Smilacis Glabrae extract 12kg,
Dandelion extract 3kg, kudzu root extract 5kg, chrysanthemum extract 5kg are stirred after the completion of addition, and it is small to stand 48
When, filtering, the filling alcoholic drink transparent to get micro- Huang.
Embodiment 3
A kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout, includes the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 14h, Extracting temperature is 60 DEG C,
Extracting solution is crossed the ultrafiltration membrane of macromolecule by reflux 3.5 hours, filtering, collects trapped fluid, and medicinal extract progress is made in trapped fluid concentration
Spray drying or be dried in vacuo to get；The solvent dosage is the second that the mass fraction of 20 times of amounts of smilax quality is 50%
Alcoholic solution；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 80 DEG C, and reflux 1.5 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 10 times of amounts of dandelion quality is 45%；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 8 hours, and Extracting temperature is 80 DEG C of reflux
2.5 hours, filtering, isolate the dregs of a decoction, be added again in the dregs of a decoction solvent be heated to 75 DEG C flow back 2 hours, filtering, merge twice
Extracting solution, is crossed the ultrafiltration membrane of macromolecule by extracting solution, collects trapped fluid, trapped fluid concentration be made medicinal extract carry out spray drying or
Person vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of pueraria lobata quality is 50%；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 50 DEG C, and reflux 4.5 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%；
（5）The preparation of health-care spirit：Choose high-quality Maotai-flavor liquor 100KL, be separately added into thereto Rhizoma Smilacis Glabrae extract 8kg,
Dandelion extract 5kg, kudzu root extract 3kg, Honegsukle flower P.E 3kg are stirred after the completion of addition, and it is small to stand 48
When, filtering, the filling alcoholic drink transparent to get micro- Huang.
Claims (5)
1. a kind of health-care spirit for having effects that auxiliary and alleviating gout, it is characterised in that contain following weight in per 100KL white wine
Raw material：
3~5kg of Rhizoma Smilacis Glabrae extract 8~12kg dandelion extracts
3~5kg of 3~5kg of kudzu root extract honeysuckles or chrysanthemum extract.
2. a kind of health-care spirit for having effects that auxiliary and alleviating gout according to claim 1, it is characterised in that per 100KL
Raw material containing following weight in white wine：
Rhizoma Smilacis Glabrae extract 10kg dandelion extracts 4kg
Kudzu root extract 4kg Honegsukle flower P.Es 4kg.
3. a kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout as claimed in claim 1 or 2, feature
It is to include the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 10~14h, Extracting temperature 60
DEG C~80 DEG C, it flows back 2.5~3.5 hours, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid is dense
Contraction be spray-dried or be dried in vacuo at medicinal extract to get；The solvent dosage is the matter of 20 times of amounts of smilax quality
Measure the ethanol solution that score is 50%；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 60 DEG C~80 DEG C, is returned
Extracting solution is crossed the ultrafiltration membrane of macromolecule by stream 1.5~2.5 hours, filtering, collects trapped fluid, and medicinal extract is made in trapped fluid concentration
Be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 10 times of amounts of dandelion quality is 45%
Ethanol solution；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 8~12 hours, and Extracting temperature is 70 DEG C
It~80 DEG C, flows back 2.5~3.5 hours, filtering isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 1.5~2.5
Hour, filtering merges extracting solution twice, and extracting solution is crossed to the ultrafiltration membrane of macromolecule, collects trapped fluid, and trapped fluid concentration is made
Medicinal extract be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 15 times of amounts of pueraria lobata quality is
50% ethanol solution；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 50 DEG C~70 DEG C, is returned
Extracting solution is crossed the ultrafiltration membrane of macromolecule by stream 3.5~4.5 hours, filtering, collects trapped fluid, and medicinal extract is made in trapped fluid concentration
Be spray-dried or be dried in vacuo to get；The solvent dosage is that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%
Ethanol solution；
（5）The preparation of chrysanthemum extract：Chrysanthemum and solvent are added into extractor, Extracting temperature is 50 DEG C~70 DEG C, reflux 30
~60 minutes, filtering isolated the dregs of a decoction, solvent is added heating extraction 30-60 minutes again in the dregs of a decoction, and filtering, merging carries twice
Take liquid, extracting solution crossed to the ultrafiltration membrane of macromolecule, collect trapped fluid, trapped fluid concentration be made medicinal extract carry out spray drying or
Vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 12 times of amounts of quality of Flos Lonicerae is 80%；
（6）The preparation of health-care spirit：Choose high quality liquor 100KL, added respectively by formula rate thereto Rhizoma Smilacis Glabrae extract,
Dandelion extract, kudzu root extract, Honegsukle flower P.E or chrysanthemum extract stir after the completion of addition, stand
48 hours, filtering, the filling alcoholic drink transparent to get micro- Huang.
4. a kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout according to claim 3, feature
It is to include the following steps：
（1）The preparation of Rhizoma Smilacis Glabrae extract：Smilax and solvent are added into extractor, impregnate 12h, Extracting temperature is 70 DEG C,
Extracting solution is crossed the ultrafiltration membrane of macromolecule by reflux 3 hours, filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is sprayed
Mist is dry or vacuum drying to get；The solvent dosage is the ethyl alcohol that the mass fraction of 20 times of amounts of smilax quality is 50%
Solution；
（2）The preparation of dandelion extract：Dandelion and solvent are added into extractor, Extracting temperature is 70 DEG C, and reflux 2 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 10 times of amounts of dandelion quality is 45%；
（3）The preparation of kudzu root extract：Pueraria lobata and solvent are added into extractor, is impregnated 10 hours, and Extracting temperature is 75 DEG C and returns
Stream 3 hours, filtering, isolates the dregs of a decoction, solvent is added again in the dregs of a decoction and is heated to reflux 2 hours, filters, and merging is extracted twice
Extracting solution is crossed the ultrafiltration membrane of macromolecule by liquid, collects trapped fluid, and trapped fluid concentration is made medicinal extract and carries out spray drying or true
Sky it is dry to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of pueraria lobata quality is 50%；
（4）The preparation of Honegsukle flower P.E：Honeysuckle and solvent are added into extractor, Extracting temperature is 60 DEG C, and reflux 4 is small
When, extracting solution is crossed the ultrafiltration membrane of macromolecule by filtering, collects trapped fluid, and trapped fluid concentration is made medicinal extract and is spray-dried
Or vacuum drying to get；The solvent dosage is the ethanol solution that the mass fraction of 15 times of amounts of quality of Flos Lonicerae is 60%；
（5）The preparation of health-care spirit：High quality liquor 100KL is chosen, is separately added into Rhizoma Smilacis Glabrae extract 10kg, dandelion thereto
Extract 4kg, kudzu root extract 4kg, Honegsukle flower P.E 4kg are stirred after the completion of addition, stand 48 hours, mistake
Filter, the filling alcoholic drink transparent to get micro- Huang.
5. a kind of preparation method for having effects that auxiliary and alleviating the health-care spirit of gout according to claim 3, feature
It is：The white wine is delicate fragrance type, Luzhou-flavor or Maotai-flavor liquor.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110184162A (en) * | 2019-07-12 | 2019-08-30 | 劲牌有限公司 | It is a kind of to have effects that improve health-care spirit of sleep and preparation method thereof |
| CN111518660A (en) * | 2020-04-29 | 2020-08-11 | 劲牌有限公司 | Health-care white spirit with effect of relieving alcoholic brain injury and preparation method thereof |
| CN113100443A (en) * | 2021-05-17 | 2021-07-13 | 卢静 | Composition and soft capsule for relieving gout and preparation method thereof |
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