CN110184162A - It is a kind of to have effects that improve health-care spirit of sleep and preparation method thereof - Google Patents
It is a kind of to have effects that improve health-care spirit of sleep and preparation method thereof Download PDFInfo
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- CN110184162A CN110184162A CN201910627266.1A CN201910627266A CN110184162A CN 110184162 A CN110184162 A CN 110184162A CN 201910627266 A CN201910627266 A CN 201910627266A CN 110184162 A CN110184162 A CN 110184162A
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
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Abstract
Have effects that improve health-care spirit of sleep and preparation method thereof the invention discloses a kind of, the health-care spirit, raw material containing following weight in every 100KL white wine: Wild jujube seeds extract 10-14kg, Fructus Citri Sarcodactylis extract 6-10kg, Semen Nelumbinis extract 6-10kg, tuckahoe extracts 4-6kg, preparation method are as follows: first successively produce Wild jujube seeds extract, Fructus Citri Sarcodactylis extract, Semen Nelumbinis extract and tuckahoe extracts, after preparing extract, 100KL base liquor is configured, 1KL is taken out from base liquor, and four kinds of extracts are made into concentrated solution through high-speed cutting dissolution, then concentrated solution is dissolved in remaining base liquor, mixed uniformly rear be rapidly frozen is filtered, to obtain the final product；Of the invention has the health-care spirit for improving sleep function, and wine body colour pool is clear and transparent, the quiet and tastefully laid out exquisiteness of fragrance, has light flowers and fruits perfume, all perfume harmonies, entrance is sweet plentiful, and rear taste is refreshing net；It is especially suitable for insomnia personage's long-term drinking.
Description
Technical field
The present invention relates to a kind of health-care spirits, especially a kind of to have effects that improve the health-care spirit of sleep and its preparation side
Method.
Background technique
The time that there is one third in all one's life of people is spent in sleep.Sleep is an elimination fatigue, conserves strength and store up energy
Process, and to the repair process for damaging cell caused by free radical, and consolidate the process of learning and memory, still not
The maturation of nerve cell is developed, but people still know little about it to the essence of sleep.People can faster be set than not having a meal by staying up
In fatal position, if staying up and being possible to death for continuous five days.In four big biological elements --- empty gas and water, sleep, the food of people
In, third is ranked in sleep, it is seen that the importance slept to the life of people.Therefore, be organized in 2001 will be every for international mental hygiene
The March 21 in year is set to " World Sleep Day ", it is seen that its importance.Adult one day suitable sleeping time should be on the left side 8h
It is right.In general, child is 10-12h, juvenile 9-10h, between twenty and fifty 7-9h, 60-70 years old old man 8-9h needs 10h in 70-90 years old,
Need 10-12h within 90 years old or more.The time point of daily sound sleep, 20 points of children were extremely at 22 points to 6 points of next day, 21 points to 5 points of the elderly
It 6 points, also varies with each individual.
According to the classification standard that international sleep association formulates, there are two different states composition (or two periods for sleep
Phase): first is that eye movement phase, abbreviation REM, this stage eyeball can not stall dynamic, non-autonomous unconscious rotation after sleep, greatly
Brain is very active, with it is awake when computer movable it is similar, dreamland majority is in this stage；Second is that the eyeball non-quick-action phase, abbreviation NREM,
This is a kind of deeper automatism, this stage is divided into four independent I-IV phases of sleep period according to Depth of sleep.
The NREM of I-IV phase lasts 80-120min, and REM lasts 20-30min.Sleep first since I phase of NREM, after II phase,
III phase, IV phase successively return to III phase, II phase, I phase, followed by REM phase again, this is a circulation, in cycles.Entire evening 8h
Meter, there is 3-5 sleep cycle, including NREM and REM, 4 sleep cycles of average out to.That is, during natural sleep,
Sleep soundly the phase in NREM() after always will appear the REM(of a period of time and non-sleep soundly the phase), and recycle 3-5 time every night, although in person simultaneously
Insentience.Sleep is an extremely complex process, and it is that batch is handed over that it is also extremely complex for, which influencing or can improve the substance of sleep,
What mistake influenced.Obviously, sleep be for brain service, reason first is that animal sleep and plant sits up, it is considered that, at least exist
The sleep of NREM is brain harmful substance because of caused by metabolism --- the repair time of cell damage caused by free radical.
Other organs can repair this damage by abandoning and replacing damaged cell, but brain can not be done so, because of brain cell
It is not regenerated, therefore it can only be repaired by shutting down.In addition, the animal that general metabolism is fast, by freedom
The speed of base damage is also fast, and sleeping time is just longer than metabolic slow animal.
Sufficient sleep should feel clearheaded after waking up, and whole body is light, micro fatigue crack, and full of energy, physical strength is vigorous.
As soon as will appear and sleep when people lacks reply since the factors such as work, marriage, economy, desire, fear cause psychological pressure
It sleeps bad or has a sleepless night.Insomnia is a kind of symptom, shows as difficulty falling asleep, sleep does not wake up with a start deeply, easily, early awakening, dreaminess, seemingly sleeps non-sleep
Deng, or even difficult dormancy all night.When sleep insufficiency, " sleep is in debt " can be rolled up, intelligence and locomitivity can be made low, reaction is slow
It is blunt.It was found that 1h fewer than normal sleep times every night, the IQ and cognitive ability of people 1 quotient of temporary decline.Asia in 2004
Continent sleep conference data shows, South Asia crowd insomnia disease incidence about 38% at present.According to Chinese Medical Association to Beijing, Shanghai, wide
The investigation on the ground such as state, Hangzhou, Nanjing finds that insomnia disease incidence is 35%, there is the accounting 43.5% of sleeping problems.China's sleep is ground
Study carefully the 200000 family domestic sleeping Questionnaire results that can be announced at 2003 " World Sleep Day ", the total insomnia rate of China is
38.2%。
There are harm below for sleep insufficiency: (1) influencing the creative thinking of brain.As extended sleep deficiency will affect greatly
The creative thinking of brain and the ability of processing things.(2) teen-age growth and development is influenced.Teen-age growth and development and growth
The secretion of hormone has certain relationship, and the secretion of growth hormone and sleep are closely related, and people has a big growth after sleeping soundly
Then there are several small secretion peaks on hormone secretion peak again, and in non-sleep state, growth hormone secretion is reduced.(3) it influences
The health of skin.Sufficient sleep can make the skin of people obtain good metabolism, and sleep insufficiency can cause skin blood capillary
The pipe stasis of blood is stagnant, and circulation is obstructed, so that the cell of skin cannot get sufficient nutrition and make skin color to accelerate the aging of skin
Seem dark and gloomy and pale, is easy to appear black eye and wrinkle.(4) lead to disease.Often sleep insufficiency or sleep disordered, meeting
The proper splitting for influencing cell can make one the worried anxiety of mood, and immunity reduces, and thus will lead to various diseases and occur, such as mind
Possibly even the mutation of cancer cell is generated through weak, flu, gastrointestinal disease etc. and leads to the generation of cancer.(5) cause obesity.It sleeps
Deficiency of sleeping can cause to disappear in human body the decline of lipoprotein concentration, while can cause the rising of appetite hormone concentration in human body.
Many insomnia and dreamful sleep patients, cannot cure or improve for a long time, form a kind of fear to sleep.Therefore, it controls
More anxious, reckless a large amount of use sleeping class Western medicine (such as stable, clonazepam, alprazolam, epiphysin).Although
The effect of insomnia is treated than more significant, but is used for a long time, not only side effect is big, damages liver kidney internal organs, leucocyte is reduced, and
It will form drug dependence, taken once interrupting, the symptom of insomnia will recur repeatedly, even more seriously.And Chinese medicine is treated
The history of existing thousand of insomnia relatively for chemicals, has many advantages, such as safe and non-toxic, effect mitigation.
Currently, the health food based on Chinese medicine for improving sleep, general is mostly 5 kinds or 5 kinds or more groups groupings
At prescription, be formulated more complex, it is more to lead to often to exist in process of production extraction step, and effective component is extracted not exclusively etc.
Problem.There is common material composition in sedative health-care food for improving sleep: semen ziziphi spinosae and extract, Schisandra chinensis and mentioning
Take object, Poria cocos and extract, epiphysin, Rhizoma Gastrodiae and extract, ganoderma lucidum and extract, wilsonii and extract, Radix Polygalae and extraction
Object, pearl, lily and extract, ginseng and extract, vitamin B6 etc., in the material composition of preceding 10 taste, traditional Chinese medicine ingredients
Occupy 90%.These health food main components are mostly nourishing qi and blood (ganoderma lucidum, wilsonii, lily, jujube), invigorating the spleen
Dampness removing (Poria cocos), tranquilizing the mind (semen ziziphi spinosae, Radix Polygalae), suppressing hyperactive liver for calming endogenous wind (pearl) highlight insomnia health care and qi-restoratives are answered to rush down
It is real, adjust the principle of internal organs yin-yang.Insomnia health food has two class of compound and Chinese medicine.
Compounds insomnia health food mainly has a melatonin, and main component is epiphysin, has rapid-action, and effect is bright
The advantages that true, but take for a long time and easily cause dependent reaction, influence the secretion of itself epiphysin, specially tolerance, dependence
Property, endocrine disturbance etc., in addition, epiphysin cannot synthesize, can only extract, it is big to obtain difficulty, higher cost.Chinese medicine health-care is particular about
" adjusting its institute inverse, except it is done harm to ", the reason of finding out insomnia, passes through the conditioning to whole body internal organs, and insomniac is helped to restore to sleep.
Semen ziziphi spinosae in tranquilizing the mind class health food object, the natural plants such as Radix Polygalae, compared with compound, advantage is more prominent:
First is that stable effective ingredients, unlike animal component easily decomposes, and the small-molecule substance being extracted from plants can more penetrate blood brain
Barrier, mental-tranquilization, curative effect are more secure;Second is that avoiding the blood-breaking effect of compound and other toxicity, use safer.
Third is that raw material easily obtains, it is cheap.Chinese medicine health-care effect stability, adverse reaction is few, economical and practical, multiple target point, polycyclic
The pharmacological action of section, multipath is that Chinese medicine is made to have original advantage.
Therefore, it by comparing compounds insomnia health medicine/food and Chinese medicine class insomnia health medicine/food, is not difficult
It was found that Chinese medicine class insomnia health food is more friendly to human health.And it is controlled the object of the invention is to draw traditional Chinese medicine ancient Chinese medicine doctor
Insomnia experience is treated, while with tcm components theory and method, excavating to have improves sleep, enriching yin and nourishing kidney, and is suitble to add
To the Chinese prescription in wine body, a health care wine with improvement sleep is developed.
Summary of the invention
The purpose of the present invention is to current many people there are problems that sleep disturbance, and relies on compounds drug/food
Product treatment is easy to treat there are dependence by Chinese medicine, and there are traditional Chinese medicine ingredients complexity, often exists in production process and extract step
Rapid more, effective component extracts incomplete problem, and a kind of of offer has effects that improve the health-care spirit of sleep and its preparation
Method.
Of the invention a kind of have effects that improve the health-care spirit of sleep, the original containing following weight in every 100KL white wine
Material:
Wild jujube seeds extract 10-14kg Fructus Citri Sarcodactylis extract 6-10kg
Semen Nelumbinis extract 6-10kg tuckahoe extracts 4-6kg.
Preferably, it is of the invention it is a kind of have effects that improve the health-care spirit of sleep, containing following heavy in every 100KL white wine
The raw material of amount:
Wild jujube seeds extract 12kg Fructus Citri Sarcodactylis extract 8kg
Semen Nelumbinis extract 8kg tuckahoe extracts 5kg.
A kind of preparation method of health-care spirit improve with sleep of the invention, includes the following steps:
(1) preparation of Wild jujube seeds extract: semen ziziphi spinosae carries out oil expression processing first, and dregs of fat yield controls between 65-80%；It will
The semen ziziphi spinosae dregs of fat are put into extractor, and pure water is added into extractor, and dosage is 4 times of filler, and circumfluence distillation, setting mentions
Taking temperature is 85-95 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, and high speed centrifugation collects clarification at 55-60 DEG C
Clarified solution is carried out double effect concentration by liquid, and setting thickening temperature is 60-70 DEG C, and being concentrated into Brix value is 30 ± 5%, and concentrate is turned
Alcohol-settling tank is moved to, stirring is opened, is slowly added to the edible alcohol that mass fraction is 95%, adjusting alcohol quality score is 45-55%
Alcohol precipitation is carried out, alcohol continues stirring 1-2 hours after adding, stand 10-12 hours, alcohol precipitation supernatant is extracted into concentration tank, if
Setting thickening temperature is 60-70 DEG C, and being concentrated into Brix value is 30 ± 5%, and concentrate is spray-dried, Wild jujube seeds extract is obtained,
In spray-drying process, air outlet temperature≤90 DEG C are controlled, dry product requires moisture content≤5%；Wild jujube seeds extract obtained
In, the mass percentage of Saponin A is 14-20%；
(2) preparation of Fructus Citri Sarcodactylis extract: fingered citron is put into extraction tank, and pure water is added into extractor, and dosage is the 8 of filler
Times, circumfluence distillation, setting Extracting temperature is 60-70 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is transferred to Alcohol-settling tank, opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, adjusts wine
Extract Iuality score is that 60-70% carries out alcohol precipitation, and alcohol continues stirring 1-2 hours after adding, stand 10-12 hours, extracts on alcohol precipitation
For clear liquid into concentration tank, setting thickening temperature is 60-70 DEG C, is concentrated into crude drug concentration 1kg/L, concentrate is spray-dried
Or vacuum drying, it obtains Fructus Citri Sarcodactylis extract, in spray-drying process, controls air outlet temperature≤90 DEG C, dry product requires moisture to contain
Amount≤5%；In process of vacuum drying, control drying temperature is 60-80 DEG C, and dry product requires moisture content≤5%；Fingered citron obtained
In extract, the mass percentage of aurantiamarin is 1.0-1.5%；
(3) preparation of Semen Nelumbinis extract: lotus seeds are put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 65-75 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 45-50 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 50-60 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is spray-dried or is dried in vacuo, obtains Semen Nelumbinis extract, in spray-drying process, controls air outlet
Temperature≤90 DEG C, dry product require moisture content≤5%；In process of vacuum drying, control drying temperature is 60-80 DEG C, dry product
It is required that moisture content≤5%；In Semen Nelumbinis extract obtained, the mass percentage of demethyl coclaurine is 8-10%；
(4) preparation of tuckahoe extracts: Poria cocos is put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 85-95 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, the maltodextrin of quality of medicinal material 20% is weighed, is added in concentrate and stirs evenly after 60-80 DEG C of pure water dissolution,
80 mesh screens are crossed, whole concentrate is obtained, whole concentrate is spray-dried or is dried in vacuo, tuckahoe extracts are obtained, it is spraying dry
During dry, air outlet temperature≤90 DEG C are controlled, dry product requires moisture content≤5%；In process of vacuum drying, drying is controlled
Temperature is 60-80 DEG C, and dry product requires moisture content≤5%；In tuckahoe extracts obtained, the quality percentage of pachymaran contains
Amount is 12-16%；
(5) preparation of health-care spirit: the base liquor that the total 100KL of high-quality delicate fragrance type, Luzhou-flavor, Maotai-flavor liquor is deployed into is chosen, is taken
Wherein 1KL base liquor, and Wild jujube seeds extract 10-14kg, Fructus Citri Sarcodactylis extract 6-10kg, Semen Nelumbinis extract 6- are added thereto
10kg, tuckahoe extracts 4-6Kg, high-speed stirred is uniform, stand 48h, using 3 microns of sinterable polymer films filter micro- Huang is transparent
Concentrated wiring liquid, the concentrated wiring liquid prepared is uniformly mixed with base liquor then, stands 24 hours, finally by the wine body mixed by cold
Freeze filtering technique to be filtered, the wine body of clear is obtained by filtration at -10 DEG C, turbidity≤0.1NTU is filling to get institute
It obtains in health-care spirit, Saponin A 5-25Mg/L, content of hesperidin 0.3-1.2Mg/L, demethyl coclaurine content is 4-
12Mg/L, the mass percentage of pachymaran are 2-6Mg/L.
Heretofore described white wine base liquor is that delicate fragrance type, Luzhou-flavor and Maotai-flavor liquor are deployed.It can be according to consumption
The mouthfeel demand of person deploys the alcoholic drink of different flavor, different flavor, different quality class.
Insomnia, Chinese medicine referred to as " is insomnia ", basic pathogenesis be imbalance of yin and yang, it is disharmony between ying and wei, brains dystrophy, have no peace of mind,
Due to qi-blood disharmony, the imbalance of yin and yang of internal organs, and then it is feeding and confused and worried to cause the heart to be become homeless.It is specifically treated according to different card marquis
Method has: help is in, and invigorating the spleen yin-nourishing, calming the liver is soothing the liver, vital energy regualting and blood circulation-promoting, clearing damp resolving sputum, heat-clearing etc..Mind activity is classified as five by Chinese medicine
It is dirty, think in Huangdi's Internal Classics: heart storing spirit, liver storing soul, idea stored in the spleen, lung storing inferior spirit, kidney storing will.
Semen ziziphi spinosae used in the present invention is sweet in flavor, enters the heart, Liver Channel, can nourishing heart yin, beneficial liver blood and have the benefits of tranquilizing the mind, be nourishing heart
The key medicine of tranquilizing the mind, cures mainly conscience deficiency of YIN-blood, and the heart is become homeless feeding, palpitaition, palpitation, amnesia, insomnia, dreaminess, the dizziness having ants in one's pants
Equal diseases.Modern pharmacological studies have shown that Semen Ziziphi Spinosae total flavonoids, jujuboside and spine date seed oil can obviously reduce the spontaneous work of mouse
It is dynamic, there is apparent calm and syngignoscism, and spine date seed oil long-time service has no tolerance.Chinese medicine angle, semen ziziphi spinosae are peaces
The core Chinese medicine of refreshing class, i.e. monarch drug in a prescription in the present invention.
It is fingered citron acrid flavour, hardship, sweet, it is warm-natured, it is nontoxic, enter liver, spleen, stomach three and passes through.With regulating qi-flowing for eliminating phlegm, cough-relieving dissipate-swelling, soothing the liver strong
A variety of medicinal functions such as spleen stomach function regulating, while also there is certain benefiting action.
Lotus seeds are sweet in flavor, puckery, mild-natured, returns spleen, kidney, the heart channel of Hang-Shaoyin.Cure mainly tonifying spleen and stopping diarrhea, stop-band, kidney-nourishing arresting seminal emission, mental-tranquilization.With
In splenasthenic diarrhea, leukorrhagia, spermatorrhea, palpitation and insomnia.
Poria cocos is sweet in flavor, light, mild-natured, return heart, lung, spleen, kidney channel.Cure mainly clearing damp and promoting diuresis, invigorating the spleen, calming heart.For edema and little urine,
Phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea are had no peace of mind, insomnia of palpitating with fear.
The four taste Chinese medicine such as semen ziziphi spinosae, fingered citron, lotus seeds, Poria cocos for selecting in the present invention is effect in mental-tranquilization class medicinal material
Preferably, most popular medicinal material, and pass through Chinese medicine Digital Extraction technique of the invention, effective content is high, manufactured health care
White wine Chinese medicine is lightly seasoned, color is shallow, and long-term drinking, which has, extends sleeping time, the health for shortening Sleep latency, improving sleep quality
White wine.Ingredients is taken from integration of drinking and medicinal herbs in prescription and health food catalogue medicinal material securely and reliably meets correlation method law
Rule require.
Compared with prior art, the present invention advantage is as follows:
1. white wine base liquor used in the present invention is the compound flavor white spirit of three fragrant unifications (giving off a strong fragrance, paste flavor, faint scent), wherein paste flavor is assigned
Giving the comfortable high-end fragrance of quiet and tastefully laid out fine and smooth, the empty cup lasting of wine body, giving off a strong fragrance assigns that wine body entrance is sweet, plentiful mellow agreeable to the taste sense,
Faint scent assigns wine body one clear pure comfortable rear taste on earth, and on the whole, the quiet and tastefully laid out exquisiteness of wine body note gas, entrance is sweet plentiful, after
Taste is clean.
2. medicinal material used in the present invention is the medicinal material of integration of drinking and medicinal herbs, domestic state-of-the-art Chinese medicine Digital Extraction is used
Technique carries out scientific and effective full-automatic extraction in strict accordance with the finger-print of medicinal material effective component, it is ensured that medicinal material effectively at
The high efficiency extraction divided, the removal of non-active ingredients.Then Wild jujube seeds extract, Fructus Citri Sarcodactylis extract, Semen Nelumbinis extract, Poria cocos are mentioned
It takes object to be added in wine body, does not influence the fragrance of wine body itself, while assigning the comfortable fragrance of a flower of wine body, fruity.
3. the health care wine for the improvement sleep that the present invention prepares is connected using " non-carbonized " flash-frozen advanced in liquor industry
The white-spirit purifying technique of continuous filtering, purifies white wine and Chinese medical extract in the case where freezing low temperature, it is ensured that Chinese medicine effectively at
The whole reservations and the intrinsic fragrance of wine body divided retain, while obtaining subzero 10 degrees Celsius or less the wine for being still able to maintain clear
Body.
4. the health care wine research for improving sleep still belongs to belongs to very widely used ordinary food scope for the first time, both
Have flavor, the mouthfeel of traditional liquor, and impart that white wine is abundant, fine and smooth, quiet and tastefully laid out flavor, and has the function of improving and sleep
The factor.
It is produced by the present invention that there are the health-care spirit for improving sleep function, products characteristics are as follows: wine body colour pool is clear and transparent,
The quiet and tastefully laid out exquisiteness of fragrance has light flowers and fruits perfume, and all perfume harmonies, entrance is sweet plentiful, and rear taste is refreshing net；And by foodsafety poison
Neo-Confucianism evaluation, it was demonstrated that it can be examined by food safety toxicology, process and sleep improvement of mice Evaluation of Functional, as a result
Determine that wine body of the present invention has the function of mouse to improve sleep function.
Specific embodiment
Embodiment 1
It is a kind of to have effects that improve the health-care spirit of sleep, the raw material containing following weight in every 100KL white wine:
Wild jujube seeds extract 12kg Fructus Citri Sarcodactylis extract 8kg
Semen Nelumbinis extract 8kg tuckahoe extracts 5kg.
A kind of preparation method of the health-care spirit improve with sleep, includes the following steps:
(1) preparation of Wild jujube seeds extract: semen ziziphi spinosae carries out oil expression processing first, and dregs of fat yield is controlled 70%；By spine date seed oil
Slag is put into extractor, and pure water is added into extractor, and dosage is 4 times of filler, and circumfluence distillation, Extracting temperature, which is arranged, is
It 90-95 DEG C, flows back 2 hours, repeats to extract three times, combined extract, high speed centrifugation collects clarified solution at 55-60 DEG C, will clarify
Liquid carries out double effect concentration, and setting thickening temperature is 60-65 DEG C, and being concentrated into Brix value is 30%, and concentrate is transferred to Alcohol-settling tank,
Stirring is opened, the edible alcohol that mass fraction is 95% is slowly added to, adjusting alcohol quality score is that 45-50% carries out alcohol precipitation, wine
Continue stirring 1.5 hours after finishing is complete, stand 12 hours, extract alcohol precipitation supernatant into concentration tank, setting thickening temperature is 60-
65 DEG C, being concentrated into Brix value is 30%, and concentrate is spray-dried, obtains Wild jujube seeds extract, in spray-drying process, control
Draught temperature≤90 DEG C are produced, dry product requires moisture content≤5%；In Wild jujube seeds extract obtained, Saponin A
Mass percentage is 18%；
(2) preparation of Fructus Citri Sarcodactylis extract: fingered citron is put into extraction tank, and pure water is added into extractor, and dosage is the 8 of filler
Times, circumfluence distillation, setting Extracting temperature is 65-70 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 65-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is transferred to Alcohol-settling tank, opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, adjusts wine
Extract Iuality score is that 60-65% carries out alcohol precipitation, and alcohol continues stirring 2 hours after adding, stand 10 hours, extracts alcohol precipitation supernatant
Into concentration tank, setting thickening temperature is 60-65 DEG C, is concentrated into crude drug concentration 1kg/L, concentrate is spray-dried, is obtained
Fructus Citri Sarcodactylis extract in spray-drying process, controls air outlet temperature≤90 DEG C, and dry product requires moisture content≤5%；It is obtained
In Fructus Citri Sarcodactylis extract, the mass percentage of aurantiamarin is 1.2%；
(3) preparation of Semen Nelumbinis extract: lotus seeds are put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 70-75 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 45-50 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 50-55 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is spray-dried, obtains Semen Nelumbinis extract, in spray-drying process, controls air outlet temperature≤90
DEG C, dry product requires moisture content≤5%；In Semen Nelumbinis extract obtained, the mass percentage of demethyl coclaurine is 9%；
(4) preparation of tuckahoe extracts: Poria cocos is put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 90-95 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 65-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, the maltodextrin of quality of medicinal material 20% is weighed, is added in concentrate and stirs evenly after 75 DEG C of pure water dissolutions, cross 80
Mesh screen obtains whole concentrate, and whole concentrate is spray-dried, and obtains tuckahoe extracts, in spray-drying process, controls out
Draught temperature≤90 DEG C, dry product require moisture content≤5%；In tuckahoe extracts obtained, the quality percentage of pachymaran contains
Amount is 14%；
(5) preparation of health-care spirit: choosing high-quality delicate fragrance type, Luzhou-flavor, Maotai-flavor and be total to the base liquor that white wine 100KL is deployed into, and
Wild jujube seeds extract 12kg, Fructus Citri Sarcodactylis extract 8kg, Semen Nelumbinis extract 8kg, tuckahoe extracts 5Kg, high-speed stirred are added thereto
Uniformly, stand 48h, filter to obtain the transparent concentrated wiring liquid of micro- Huang using 3 microns of sinterable polymer films, then by the concentrated wiring liquid prepared and
Base liquor is uniformly mixed, and is stood 24 hours, is finally filtered the wine body mixed by freezing and filtering technique, at -10 DEG C
The wine body of clear is obtained by filtration, turbidity≤0.1NTU is filling to get in gained health-care spirit, Saponin A is
16.4Mg/L, content of hesperidin 0.698Mg/L, demethyl coclaurine content are 6.03Mg/L, and pachymaran content is 3.05Mg/
L。
The white wine base liquor is delicate fragrance type, Luzhou-flavor, Maotai-flavor liquor are deployed.
By the influence in the mice sleep incubation period and sleeping time that induce above threshold dose of sodium pentobarbitone, to above threshold agent
The influence test for measuring yellow Jackets induced hypnotic percentage, improves sleep function for having obtained by the embodiment of the present invention 1
Health-care spirit carried out functional test in the Animal Lab. of our company.Relevant food Toxicological evaluation (animal
Test) and improve sleep Evaluation of Functional (animal experiment) test situation it is as follows:
(1) food safety evaluation on toxicology (zoopery)
Test result: the tested material belongs to nontoxic grade substance
Test basis: GB15193 .3-94 " toxicological evaluation of food safety procedure and method "
As a result with judgement: the daily recommended intake 120ml of this wine body human body, press adult 60kg batheroom scale, recommend intake dosage be 2
.0ml/kg .bw.The acute toxicity tests show improvement sleep health care wine of the invention to the half lethal dose of mouse
(LD50) 200 .0ml/kg .bw of >, true border innocuous substance.Salmonella reversion test, Micronuclei In The Mouse Bone Marrow test and teratospermia try
Testing is feminine gender.In 30 days feeding trials of rat, by 25 times of human body recommended intake, 50 times, 100 times of (i.e. 50,100,200
Ml/kg .bw) tested material is given, and Normal group is set up, measurement result shows the growth of each group rat body weight, food use
The indexs such as rate, dirty body ratio, hematology and serum biochemistry in range of normal value, each dosage group with accordingly compare group difference and do not have
There is conspicuousness；Also without finding Poisoning lesion related with tested material in liver,kidney,spleen, stomach and intestine, ovary and testopathy inspection.Root
According to " health food is examined and assessment technique specification " (version in 2003), determine that this wine body is examined by food safety toxicology.
(2) improve the Evaluation of Functional (animal experiment) of sleep
Test result: having improves sleep effect
Test basis: " health food functional evaluation program and the method for inspection "
Inspection result and judgement: this wine body adult recommends intake 100ml/d, and based on adult body weight 60kg, recommended intake is every
1 .67 ml/kg .bw of day, mouse press 10,20,30 multiple doses (i.e. 16.7,33.3,50.0ml/kg of human body recommended intake
.bw the health care wine of improvement sleep of the invention) is given.The experimental results showed that compared with Normal group and alcohol control group,
Sleep rate is without obvious change after each dosage group mouse is directly slept and yellow Jackets sub-threshold dose (43 ml/kg .bw) hypnosis
Change；20 times, 30 times of two dosage group can be obviously prolonged yellow Jackets (57 ml/kg .bw) induction sleeping time, shorten bar ratio
The Sleep latency of appropriate sodium (376 ml/kg .bw) induction.According to " health food examine with assessment technique specification " (2003
Version), determining that this wine body has mouse improves sleep function.
It can be seen that health-care spirit manufactured in the present embodiment from above-mentioned test result, examined by food safety toxicology
Test and improve the evaluation of sleep function, it was demonstrated that white wine manufactured in the present embodiment has the effect of improvement is slept, and safe nothing really
Toxic side effect.
Embodiment 2
It is a kind of to have effects that improve the health-care spirit of sleep, the raw material containing following weight in every 100KL white wine:
Wild jujube seeds extract 14kg Fructus Citri Sarcodactylis extract 6kg
Semen Nelumbinis extract 10kg tuckahoe extracts 4kg.
A kind of preparation method of the health-care spirit improve with sleep, includes the following steps:
(1) preparation of Wild jujube seeds extract: semen ziziphi spinosae carries out oil expression processing first, and dregs of fat yield controls between 80%；By wild jujube
The benevolence dregs of fat are put into extractor, and pure water is added into extractor, and dosage is 4 times of filler, and circumfluence distillation, setting is extracted warm
Degree is 85-90 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, and high speed centrifugation collects clarified solution at 55-60 DEG C, will
Clarified solution carries out double effect concentration, and setting thickening temperature is 65-70 DEG C, and being concentrated into Brix value is 35%, and concentrate is transferred to alcohol precipitation
Tank opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, and adjusting alcohol quality score is that 50-55% carries out alcohol precipitation,
Alcohol continues stirring 2 hours after adding, stand 10 hours, extracts alcohol precipitation supernatant into concentration tank, and setting thickening temperature is 65-
70 DEG C, being concentrated into Brix value is 35%, and concentrate is spray-dried, obtains Wild jujube seeds extract, in spray-drying process, control
Draught temperature≤90 DEG C are produced, dry product requires moisture content≤5%；In Wild jujube seeds extract obtained, Saponin A
Mass percentage is 20%；
(2) preparation of Fructus Citri Sarcodactylis extract: fingered citron is put into extraction tank, and pure water is added into extractor, and dosage is the 8 of filler
Times, circumfluence distillation, setting Extracting temperature is 60-65 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-65 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is transferred to Alcohol-settling tank, opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, adjusts wine
Extract Iuality score is that 65-70% carries out alcohol precipitation, and alcohol continues stirring 1 hour after adding, stand 10 hours, extracts alcohol precipitation supernatant
Into concentration tank, setting thickening temperature is 65-70 DEG C, is concentrated into crude drug concentration 1kg/L, concentrate is dried in vacuo, is obtained
Fructus Citri Sarcodactylis extract, in process of vacuum drying, control drying temperature is 60-80 DEG C, and dry product requires moisture content≤5%；It is obtained
In Fructus Citri Sarcodactylis extract, the mass percentage of aurantiamarin is 1.0%；
(3) preparation of Semen Nelumbinis extract: lotus seeds are put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 65-70 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 45-50 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 55-60 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is dried in vacuo, obtains Semen Nelumbinis extract, in process of vacuum drying, control drying temperature is 70-80
DEG C, dry product requires moisture content≤5%；In Semen Nelumbinis extract obtained, the mass percentage of demethyl coclaurine is 10%；
(4) preparation of tuckahoe extracts: Poria cocos is put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 85-90 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-65 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, the maltodextrin of quality of medicinal material 20% is weighed, is added in concentrate and stirs evenly after 60 DEG C of pure water dissolutions, cross 80
Mesh screen obtains whole concentrate, and whole concentrate is dried in vacuo, and obtains tuckahoe extracts, and in process of vacuum drying, control is dry
Dry temperature is 70-80 DEG C, and dry product requires moisture content≤5%；In tuckahoe extracts obtained, the quality percentage of pachymaran
Content is 12%；
(5) preparation of health-care spirit: choosing high-quality delicate fragrance type, Luzhou-flavor, Maotai-flavor and be total to the base liquor that white wine 100KL is deployed into, and
Wild jujube seeds extract 14kg, Fructus Citri Sarcodactylis extract 6kg, Semen Nelumbinis extract 10kg, tuckahoe extracts 4Kg, high-speed stirring are added thereto
It mixes uniformly, stands 48h, filter to obtain the transparent concentrated wiring liquid of micro- Huang, the concentrated wiring liquid that then will be prepared using 3 microns of sinterable polymer films
It is uniformly mixed with base liquor, stands 24 hours, be finally filtered the wine body mixed by freezing and filtering technique, at -10 DEG C
Under the wine body of clear is obtained by filtration, turbidity≤0.1NTU is filling to get in gained health-care spirit, Saponin A is
25Mg/L, content of hesperidin 0.3Mg/L, demethyl coclaurine content are 12Mg/L, and pachymaran content is 2Mg/L.
The white wine base liquor is delicate fragrance type, Luzhou-flavor, Maotai-flavor liquor are deployed.
Embodiment 3
It is a kind of to have effects that improve the health-care spirit of sleep, the raw material containing following weight in every 100KL white wine:
Wild jujube seeds extract 10kg Fructus Citri Sarcodactylis extract 10kg
Semen Nelumbinis extract 6kg tuckahoe extracts 6kg.
A kind of preparation method of the health-care spirit improve with sleep, includes the following steps:
(1) preparation of Wild jujube seeds extract: semen ziziphi spinosae carries out oil expression processing first, and dregs of fat yield controls between 65%；By wild jujube
The benevolence dregs of fat are put into extractor, and pure water is added into extractor, and dosage is 4 times of filler, and circumfluence distillation, setting is extracted warm
Degree is 87-92 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, and high speed centrifugation collects clarified solution at 55-60 DEG C, will
Clarified solution carries out double effect concentration, and setting thickening temperature is 63-68 DEG C, and being concentrated into Brix value is 25%, and concentrate is transferred to alcohol precipitation
Tank opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, and adjusting alcohol quality score is that 47-52% carries out alcohol precipitation,
Alcohol continues stirring 1 hour after adding, stand 11 hours, extracts alcohol precipitation supernatant into concentration tank, and setting thickening temperature is 63-
68 DEG C, being concentrated into Brix value is 25%, and concentrate is spray-dried, obtains Wild jujube seeds extract, in spray-drying process, control
Draught temperature≤90 DEG C are produced, dry product requires moisture content≤5%；In Wild jujube seeds extract obtained, Saponin A
Mass percentage is 14%；
(2) preparation of Fructus Citri Sarcodactylis extract: fingered citron is put into extraction tank, and pure water is added into extractor, and dosage is the 8 of filler
Times, circumfluence distillation, setting Extracting temperature is 62-67 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 62-67 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is transferred to Alcohol-settling tank, opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, adjusts wine
Extract Iuality score is that 62-67% carries out alcohol precipitation, and alcohol continues stirring 1.5 hours after adding, stand 11 hours, extracts alcohol precipitation supernatant
For liquid into concentration tank, setting thickening temperature is 62-67 DEG C, is concentrated into crude drug concentration 1kg/L, concentrate is spray-dried,
Fructus Citri Sarcodactylis extract, in spray-drying process, control air outlet temperature≤90 DEG C, dry product requires moisture content≤5%；It is made
Fructus Citri Sarcodactylis extract in, the mass percentage of aurantiamarin is 1.5%；
(3) preparation of Semen Nelumbinis extract: lotus seeds are put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 67-72 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 45-50 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 53-58 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is spray-dried, obtains Semen Nelumbinis extract, in spray-drying process, controls air outlet temperature≤90
DEG C, dry product requires moisture content≤5%；In Semen Nelumbinis extract obtained, the mass percentage of demethyl coclaurine is 8%；
(4) preparation of tuckahoe extracts: Poria cocos is put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 87-92 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 63-68 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, the maltodextrin of quality of medicinal material 20% is weighed, is added in concentrate and stirs evenly after 80 DEG C of pure water dissolutions, cross 80
Mesh screen obtains whole concentrate, and whole concentrate is spray-dried, and obtains tuckahoe extracts, in spray-drying process, controls out
Draught temperature≤90 DEG C, dry product require moisture content≤5%；In tuckahoe extracts obtained, the quality percentage of pachymaran contains
Amount is 16%；
(5) preparation of health-care spirit: choosing high-quality delicate fragrance type, Luzhou-flavor, Maotai-flavor and be total to the base liquor that white wine 100KL is deployed into, and
Wild jujube seeds extract 10kg, Fructus Citri Sarcodactylis extract 10kg, Semen Nelumbinis extract 6kg, tuckahoe extracts 6Kg, high-speed stirring are added thereto
It mixes uniformly, stands 48h, filter to obtain the transparent concentrated wiring liquid of micro- Huang, the concentrated wiring liquid that then will be prepared using 3 microns of sinterable polymer films
It is uniformly mixed with base liquor, stands 24 hours, be finally filtered the wine body mixed by freezing and filtering technique, at -10 DEG C
Under the wine body of clear is obtained by filtration, turbidity≤0.1NTU is filling to get in gained health-care spirit, Saponin A is
5Mg/L, content of hesperidin 1.2Mg/L, demethyl coclaurine content are 4Mg/L, and pachymaran content is 6Mg/L.
The white wine base liquor is delicate fragrance type, Luzhou-flavor, Maotai-flavor liquor are deployed.
Claims (4)
1. a kind of have effects that improve the health-care spirit of sleep, it is characterised in that the original containing following weight in every 100KL white wine
Material:
Wild jujube seeds extract 10-14kg Fructus Citri Sarcodactylis extract 6-10kg
Semen Nelumbinis extract 6-10kg tuckahoe extracts 4-6kg.
2. a kind of health-care spirit with improvement sleep according to claim 1, it is characterised in that every 100KL white wine
In the raw material containing following weight:
Wild jujube seeds extract 12kg Fructus Citri Sarcodactylis extract 8kg
Semen Nelumbinis extract 8kg tuckahoe extracts 5kg.
3. a kind of preparation method of health-care spirit improve with sleep as claimed in claim 1 or 2, it is characterised in that
Include the following steps:
(1) preparation of Wild jujube seeds extract: semen ziziphi spinosae carries out oil expression processing first, and dregs of fat yield controls between 65-80%；It will
The semen ziziphi spinosae dregs of fat are put into extractor, and pure water is added into extractor, and dosage is 4 times of filler, and circumfluence distillation, setting mentions
Taking temperature is 85-95 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, and high speed centrifugation collects clarification at 55-60 DEG C
Clarified solution is carried out double effect concentration by liquid, and setting thickening temperature is 60-70 DEG C, and being concentrated into Brix value is 30 ± 5%, and concentrate is turned
Alcohol-settling tank is moved to, stirring is opened, is slowly added to the edible alcohol that mass fraction is 95%, adjusting alcohol quality score is 45-55%
Alcohol precipitation is carried out, alcohol continues stirring 1-2 hours after adding, stand 10-12 hours, alcohol precipitation supernatant is extracted into concentration tank, if
Setting thickening temperature is 60-70 DEG C, and being concentrated into Brix value is 30 ± 5%, and concentrate is spray-dried, Wild jujube seeds extract is obtained,
In spray-drying process, air outlet temperature≤90 DEG C are controlled, dry product requires moisture content≤5%；Wild jujube seeds extract obtained
In, the mass percentage of Saponin A is 14-20%；
(2) preparation of Fructus Citri Sarcodactylis extract: fingered citron is put into extraction tank, and pure water is added into extractor, and dosage is the 8 of filler
Times, circumfluence distillation, setting Extracting temperature is 60-70 DEG C, is flowed back 2 hours, is repeated to extract three times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is transferred to Alcohol-settling tank, opens stirring, is slowly added to the edible alcohol that mass fraction is 95%, adjusts wine
Extract Iuality score is that 60-70% carries out alcohol precipitation, and alcohol continues stirring 1-2 hours after adding, stand 10-12 hours, extracts on alcohol precipitation
For clear liquid into concentration tank, setting thickening temperature is 60-70 DEG C, is concentrated into crude drug concentration 1kg/L, concentrate is spray-dried
Or vacuum drying, it obtains Fructus Citri Sarcodactylis extract, in spray-drying process, controls air outlet temperature≤90 DEG C, dry product requires moisture to contain
Amount≤5%；In process of vacuum drying, control drying temperature is 60-80 DEG C, and dry product requires moisture content≤5%；Fingered citron obtained
In extract, the mass percentage of aurantiamarin is 1.0-1.5%；
(3) preparation of Semen Nelumbinis extract: lotus seeds are put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 65-75 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 45-50 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 50-60 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, concentrate is spray-dried or is dried in vacuo, obtains Semen Nelumbinis extract, in spray-drying process, controls air outlet
Temperature≤90 DEG C, dry product require moisture content≤5%；In process of vacuum drying, control drying temperature is 60-80 DEG C, dry product
It is required that moisture content≤5%；In Semen Nelumbinis extract obtained, the mass percentage of demethyl coclaurine is 8-10%；
(4) preparation of tuckahoe extracts: Poria cocos is put into extraction tank, and pure water is added into extractor, and dosage is the 4 of filler
Times, circumfluence distillation, setting Extracting temperature is 85-95 DEG C, is flowed back 2 hours, repeats to extract 2 times, combined extract, 55-60 DEG C
Lower high speed centrifugation collects clarified solution, and clarified solution is carried out double effect concentration, and setting thickening temperature is 60-70 DEG C, and it is dense to be concentrated into crude drug
1kg/L is spent, the maltodextrin of quality of medicinal material 20% is weighed, is added in concentrate and stirs evenly after 60-80 DEG C of pure water dissolution,
80 mesh screens are crossed, whole concentrate is obtained, whole concentrate is spray-dried or is dried in vacuo, tuckahoe extracts are obtained, it is spraying dry
During dry, air outlet temperature≤90 DEG C are controlled, dry product requires moisture content≤5%；In process of vacuum drying, drying is controlled
Temperature is 60-80 DEG C, and dry product requires moisture content≤5%；In tuckahoe extracts obtained, the quality percentage of pachymaran contains
Amount is 12-16%；
(5) preparation of health-care spirit: choosing high-quality delicate fragrance type, Luzhou-flavor, Maotai-flavor and be total to the base liquor that white wine 100KL is deployed into, and
Wild jujube seeds extract 10-14kg, Fructus Citri Sarcodactylis extract 6-10kg, Semen Nelumbinis extract 6-10kg, tuckahoe extracts 4- are added thereto
6Kg, high-speed stirred is uniform, stands 48h, filters to obtain the transparent concentrated wiring liquid of micro- Huang using 3 microns of sinterable polymer films, then will match
Good concentrated wiring liquid is uniformly mixed with base liquor, is stood 24 hours, was finally carried out the wine body mixed by freezing and filtering technique
Filter, is obtained by filtration the wine body of clear at -10 DEG C, turbidity≤0.1NTU, it is filling to get, in gained health-care spirit, wild jujube
Benevolence saponin A is 5-25Mg/L, and content of hesperidin 0.3-1.2Mg/L, demethyl coclaurine content is 4-12Mg/L, and pachymaran contains
Amount is 2-6Mg/L.
4. a kind of preparation method of health-care spirit improve with sleep as claimed in claim 3, it is characterised in that: institute
White wine base liquor is stated to deploy for delicate fragrance type, Luzhou-flavor, Maotai-flavor liquor.
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