CN108498427B - High-permeability moisturizing emulsion and preparation method thereof - Google Patents

Abstract

The invention discloses a high-permeability moisturizing emulsion, aiming at providing a moisturizing emulsion with high stability, high permeability and high moisturizing performance; the technical scheme comprises phase A: 1-8% of cyclopentasiloxane/cyclohexasiloxane or polydimethylsiloxane, 1-8% of isononyl isononanoate or isododecane and the like; b phase component: 1-8% of glycerol, 1-8% of betaine and the like; c phase component: acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer 0.05-0.5%, carbomer 0.1-0.6%, and water 10-20%; and (3) phase D component: 1-8% of dipropylene glycol or 1.3 propylene glycol and 0.1-0.8% of preservative A; phase E component: 0.05-0.5% of carambola leaf extract, 0.05-0.5% of salix flexuoskii leaf extract, 0.02-0.3% of sedum sarmentosum extract and 0.01-0.1% of desert rose leaf cell extract; and F phase component: 0.05 to 0.2 percent of sodium hydroxide and 2 to 5 percent of water; phase G: dipropylene glycol or 1.3 propanediol 2-10%, etc., belonging to the technical field of cosmetics.

Description

High-permeability moisturizing emulsion and preparation method thereof

Technical Field

The invention discloses an emulsion, in particular to a high-permeability moisturizing emulsion, belonging to the technical field of skin care products.

Background

With age, the skin has a lower and lower ability to shrink, resulting in dull yellow and dull face, wrinkles, and the like. The lotion is a liquid cream skin care product, has good skin moistening effect and moisturizing effect because the lotion looks pure white like milk, and is particularly suitable for dry spring and autumn.

Emulsion cosmetics having a fluid state at normal temperature are called emulsions. Emulsions are systems of two liquids which are immiscible with each other, in which one phase is dispersed as fine droplets in the other phase, usually one phase, which is present in the form of liquid droplets, is referred to as the dispersed or internal phase and the other phase is referred to as the dispersion medium or external phase. The inner phase and the outer phase in the cosmetic system are not single substances generally, but are a mixture of a plurality of water-soluble components and oil-soluble components, for example, the water phase can be composed of water, water-soluble high molecular polymers and the like, and the oil phase can be composed of white oil, fatty acid, synthetic oil and the like. In order to form a stable emulsion, an emulsifier is added into an oil-water system, and emulsification is carried out by a certain emulsification method, so as to provide stability of the product.

The milky liquid cosmetics on the market are various in types, but the formula and the preparation process of the milky liquid cosmetics cannot be knocked out, the milky liquid cosmetics seem to be the same simple mixed preparation method, and the milky liquid cosmetics are lack of scientificity. Taking cosmetics of an O/W emulsification system as an example, the documents of modern cosmetic science and technology, cosmetic formula technical manual, application of surfactant in formula and the like are consulted, and the most conventional and popular preparation method introduced by the documents is that water phase in the formula is poured into oil phase or oil phase in the formula is poured into water phase, and then the materials are mixed and uniformly dispersed together by matching with external force for homogenization. Although the method is simple and convenient, the selection of the emulsifier is not high, and the common emulsifier basically can meet the requirements, the technology cannot meet the scientificity of the cosmetics, the stability and safety risk of the product are high, and the skin care effect of the cosmetics is also reduced by half.

In addition, the moisturizing performance of the emulsion on the market is better when the emulsion is used, but the skin feels dry obviously in a small meeting and the water locking performance is poorer.

Disclosure of Invention

In view of the above problems, it is an object of the present invention to provide a moisturizing emulsion having high stability, high permeability and high moisturizing properties.

The second technical scheme of the invention is to provide a preparation method of the moisturizing emulsion.

Therefore, the first technical scheme provided by the invention is as follows:

a high-permeability moisturizing emulsion comprises raw material components of an A phase, a B phase, a C phase, a D phase, an E phase, an F phase and a G phase in percentage by mass as follows:

phase A component: cyclopentadimethylsiloxane// cyclohexasiloxane or polydimethylsiloxane 1-8%, isononyl isononanoate or isododecane 1-8%, PEG-40 hydrogenated castor oil or PEG-60 hydrogenated castor oil 0.1-1%, bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane// methoxy PEG/PPG-25/4 polydimethylsiloxane// caprylic/capric triglyceride 0.3-5%;

b phase component: 1-8% of glycerol, 1-8% of betaine, 0.02-0.2% of EDTA disodium and 10-60% of water;

c phase component: acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer 0.05-0.5%, carbomer 0.1-0.6%, and water 10-20%;

and (3) phase D component: 1-8% of dipropylene glycol or 1.3 propylene glycol and 0.1-0.8% of preservative A;

phase E component: 0.05-0.5% of carambola leaf extract, 0.05-0.5% of salix flexuoskii leaf extract, 0.02-0.3% of sedum sarmentosum extract and 0.01-0.1% of desert rose leaf cell extract; 0.05 to 0.5 percent of glyceramide ethanol methacrylate/stearyl alcohol methacrylate copolymer;

and F phase component: 0.05 to 0.2 percent of sodium hydroxide and 2 to 5 percent of water;

a G phase component: 2-10% of dipropylene glycol or 1.3 propylene glycol, 2-10% of water, 0.05-0.2% of preservative B and 0.1-1% of sodium di (lauramide glutamine) lysine;

phase H component: the balance of water.

Further, in the high-permeability moisturizing emulsion, the preservative A is phenoxyethanol// ethylhexyl glycerin.

Further, in the high-permeability moisturizing emulsion, the preservative B is methyl hydroxybenzoate.

Further, in the above high permeability moisturizing emulsion, the phase E component further comprises: 0.05-0.4% of radix ophiopogonis extract and 0.05-0.5% of catalpa bark/leaf extract.

The second technical scheme provided by the invention is as follows:

the preparation method of the high-permeability moisturizing emulsion sequentially comprises the following steps:

1) soaking carbomer in phase C in advance to completely wet it for use; mixing and stirring the D-phase raw material uniformly at normal temperature for later use; dissolving the F phase at normal temperature for later use;

2) adding the raw materials of the phase B into an emulsifying pot, stirring and heating to 90-95 ℃, dissolving, then adding the raw materials of the phase C, stirring uniformly, preserving heat at 90 +/-3 ℃ for 15-20 minutes to completely defoam, cooling to 50 +/-3 ℃, then respectively adding the raw materials of the phase D and the phase E, stirring uniformly, finally adding the dissolved raw material of the phase F, stirring uniformly, cooling to 40 +/-3 ℃ for later use, and obtaining a first mixture;

3) adding the raw materials of phase A into an oil phase pot, mixing and heating to 80-85 deg.C, stirring for dissolving, and keeping the temperature at 80 + -3 deg.C for use;

4) adding the raw materials of the G phase into a water phase pot, stirring and heating to 70-75 ℃, dissolving, and keeping the temperature at 70 +/-3 ℃ for later use;

5) pumping the pretreated phase A into the water phase pot from the oil pot under the normal stirring and high-speed homogenization state of the water phase pot filled with the phase G, continuing to perform high-speed homogenization for 10-15 minutes after pumping, adding water of the phase H into the water phase pot after the homogenization is finished, stirring for 5-8 minutes, and uniformly stirring for later use to obtain a second mixture;

6) adding the second mixture into the prepared first mixture, stirring for 10-15 minutes, and stirring uniformly.

Compared with the prior art, the technical scheme provided by the invention has the following technical advantages:

1. the technical scheme provided by the invention is that the adopted amino acid non-ionic emulsifier sodium di (lauramide glutamine) lysine has no HLB value dependence, is safe, mild and degradable, and has a unique double-lock amphiphilic molecular structure: the complex hydrophobic group and the complex hydrophilic group are combined to form a double-lock structure, the double-lock structure has high surface activity, so that the double-lock structure has various excellent characteristics such as emulsification, solubilization and dispersion capacities, the product can be endowed with excellent stability, the core component of the double-lock structure is combined with amido bonds, and contains a plurality of hydrophilic tails, and the PEG-40/PEG-40 hydrogenated castor oil with excellent solubilization performance and emulsification performance is combined. The technical scheme breakthroughs the use of PEG-40 hydrogenated castor oil as an auxiliary emulsifier for double-locked amino acid micro-emulsification and D-phase emulsification, and the compounded plant extract has good affinity with skin, can form a net structure to gently wrap the skin, remodels the tender skin rich in softness and elasticity, and has the function of protecting the skin barrier.

2. The technical scheme provided by the invention contains effective components such as sodium bis (lauramide glutamine) lysine, PEG-40 hydrogenated castor oil, an carambola leaf extract, a salix frutescens leaf extract, a sedum sarmentosum extract and a desert rose leaf cell extract, a micro-capsule structure with small particle size is formed in the product through double-locked amino acid micro-emulsification and D-phase emulsification, and nutritional ingredients in the product are wrapped in the micro-capsules.

3. The technical scheme of the invention also comprises a plurality of anti-inflammatory and antiallergic components, namely an ophiopogon root extract and a catalpa bark/leaf extract, and the extracts are matched with PEG-40 hydrogenated castor oil as an auxiliary emulsifier for double-locked amino acid micro-emulsification and D-phase emulsification to form a formula, so that the synergy is realized, the adhesion of the upper layer of the epidermis is enhanced, the barrier function of the skin is recombined, excessive loss of skin moisture is prevented, the disintegration of the horny layer is reduced, the moisturizing effect is achieved, the skin can be effectively relieved, the skin is enabled to have cool feeling, and the effects of sterilization, skin moisture regulation and nano-scale skin membrane formation on the skin are achieved to protect the skin from external stimulation.

4. According to the technical scheme, the nano-scale involucra can be formed on the skin, so that the skin is protected from external stimulation. The skin care product has the advantages of long-acting moisture retention, skin dryness prevention, skin lipid film reconstruction, firmer skin, free radical inhibition, oxidation resistance and aging resistance.

Detailed Description

The claims of the present invention are described in further detail below with reference to specific embodiments.

Example 1

The invention provides a high-permeability moisturizing emulsion which specifically comprises the following components and contents:

example 2

The invention provides a high-permeability moisturizing emulsion which specifically comprises the following components and contents:

example 3

The invention provides a high-permeability moisturizing emulsion which specifically comprises the following components and contents:

example 4

The invention provides a high-permeability moisturizing emulsion which specifically comprises the following components and contents:

example 5

The invention provides a high-permeability moisturizing emulsion which specifically comprises the following components and contents:

examples 1 to 5 a method for preparing a high permeability moisturizing emulsion, comprising the following steps in order:

1) soaking carbomer in phase C in advance to completely wet it for use; mixing and stirring the D-phase raw material uniformly at normal temperature for later use; dissolving the F phase at normal temperature for later use;

2) adding the raw materials of the phase B into an emulsifying pot, stirring and heating to 90-95 ℃, dissolving, then adding the raw materials of the phase C, stirring uniformly, preserving heat at 90 +/-3 ℃ for 15-20 minutes to completely defoam, cooling to 50 +/-3 ℃, then respectively adding the raw materials of the phase D and the phase E, stirring uniformly, finally adding the dissolved raw material of the phase F, stirring uniformly, cooling to 40 +/-3 ℃ for later use, and obtaining a first mixture;

3) adding the raw materials of phase A into an oil phase pot, mixing and heating to 80-85 deg.C, stirring for dissolving, and keeping the temperature at 80 + -3 deg.C for use;

4) adding the raw materials of the G phase into a water phase pot, stirring and heating to 70-75 ℃, dissolving, and keeping the temperature at 70 +/-3 ℃ for later use;

5) pumping the pretreated phase A into the water phase pot from the oil pot under the normal stirring and high-speed homogenization state of the water phase pot filled with the phase G, continuing to perform high-speed homogenization for 10-15 minutes after pumping, adding water of the phase H into the water phase pot after the homogenization is finished, stirring for 5-8 minutes, and uniformly stirring for later use to obtain a second mixture;

6) adding the second mixture into the prepared first mixture, stirring for 10-15 minutes, and stirring uniformly.

In order to prove the effect of the high-permeability moisturizing emulsion provided by the application, comparative experimental examples and experimental effect examples are given below.

Comparative example 1

The components provided by the comparative example are completely the same as those in example 1, and the preparation methods are different, specifically:

1) soaking the C-phase carbomer completely in advance for later use; mixing and stirring the phase D raw materials uniformly at normal temperature for later use; dissolving the F-phase sodium hydroxide by using deionized water at normal temperature to be transparent for later use; mixing and heating the raw materials of the phase A to 80-85 ℃, and uniformly stirring and dissolving for later use; heating the raw materials of the G phase to 70-75 ℃, stirring and dissolving for later use;

2) adding the raw materials of phase B into an emulsifying pot, stirring and heating to 90-95 ℃, dissolving, then adding the raw materials of phase C and phase H, stirring uniformly, preserving heat at 90 +/-3 ℃ for 15-20 minutes, defoaming completely, cooling to 70-75 ℃, then sequentially adding the raw materials of phase A and phase G, stirring uniformly, cooling to 50 +/-3 ℃, then respectively adding the raw materials of phase D and phase E, stirring uniformly, finally adding the raw materials of phase F, and stirring uniformly.

Comparative example 2

This comparative example provides a composition that differs from example 1 in the absence of PEG-40 hydrogenated castor oil and is prepared in the same manner.

Comparative example 3

This comparative example provides a composition which differs from that of example 1 by the absence of the phase G component, omitting this step and the other steps being identical.

Comparative example 4

This comparative example provides a composition which differs from that of example 1 in that PEG-20 sorbitan cocoate is used instead of sodium di (lauramidoglutamine) lysine, and the other steps are the same.

Example 5

The composition of this comparative example differs from that of example 1 in that the extract of Averrhoa carambola and the extract of Epilobium fretschneideri in the E phase fraction are replaced by the extract of Sedum sarmentosum Bunge, and the other steps are the same.

Experimental data for examples 1 to 5 and comparative examples 1 to 5 of the present application are given below.

Experimental example 1

Skin seal patch test

The test substance was the high permeability moisturizing emulsions of examples 1-5 of the present invention. The subjects were 100 volunteers with healthy skin.

The test method comprises placing the tested object into a spot tester with dosage of about 0.020 g-0.025 g, applying the spot tester with the tested object on the back or forearm curve side of the tested object with non-irritating adhesive tape, and lightly pressing with palm to uniformly apply on skin for 24 h. The test substance was removed after 24 hours, and the skin reaction was observed at 0.5, 24, and 48 hours after patch removal, respectively, and the results were recorded according to the skin reaction classification standard in the "cosmetic hygiene standards" (2007 edition), with the identification standard shown in table 1 and the test results shown in table 2.

TABLE 1 identification standards

Grade	Identification criteria
		0	Has no irritation and erythema
1	Mild erythema
		2	Erythema
3	Erythema, pimples, blisters
		4	Severe edema and bulla

TABLE 2 Patch test results

As can be seen from Table 2, the high permeability moisturizing emulsions of examples 1 to 5 of the present invention did not cause any allergy or discomfort to the human body, indicating that the high permeability moisturizing emulsions of the present invention are safe and non-irritating.

Experimental example 2

Moisture retention efficacy test

The capacitance method is used for measuring the moisture content of the human skin stratum corneum, and is based on the obvious difference of dielectric constants of water and other substances, the capacitance values of the measured skin are different according to the moisture content of the skin stratum corneum, and the parameters can represent the moisture content of the skin.

100 subjects of 20-40 years old were selected and randomized into 10 groups of 10. The test subjects used the emulsions of examples 1 to 5 and comparative examples 1 to 5 for 30 days, respectively, once a day in the morning and evening.

Skin hydration was measured on day 0 and day 30 using a skin hydration tester, Corneometer CM825, and skin hydration before and after the application of the lotion was evaluated. The moisturizing efficacy test results are shown in table 3.

TABLE 3 moisture content variation of skin

	Water content at day 0	Moisture content on day 30	Moisture content increase rate (%)
				Example 1	31.28	39.03	24.78
Example 2	33.07	40.75	23.24
				Example 3	30.46	38.50	26.39
Example 4	31.83	38.33	20.43
				Example 5	32.54	39.65	21.86
Comparative example 1	32.19	33.89	5.28
				Comparative example 2	33.21	36.78	10.75
Comparative example 3	32.54	34.89	7.23
				Comparative example 4	30.87	33.84	9.63
Comparative example 5	31.62	34.40	8.79

As can be seen from the experimental results in table 3, the high permeability moisturizing emulsions of examples 1 to 5 of the present invention can significantly increase the moisture content of the skin, which illustrates that the high permeability moisturizing emulsions of examples 1 to 5 of the present invention have good moisturizing effects. After the high-permeability moisturizing emulsion of example 3 of the invention is continuously used for 30 days, the moisture content of the skin can be increased by 26.39%.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims (4)

1. The high-permeability moisturizing emulsion is characterized by comprising the following raw material components in percentage by mass:

phase A component: 1-8% of cyclopentadimethylsiloxane// cyclohexasiloxane or polydimethylsiloxane, 1-8% of isononyl isononanoate or isododecane, 0.1-1% of PEG-40 hydrogenated castor oil or PEG-60 hydrogenated castor oil, 0.3-5% of bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane// methoxy PEG/PPG-25/4 polydimethylsiloxane// caprylic/capric triglyceride;

b phase component: 1-8% of glycerol, 1-8% of betaine, 0.02-0.2% of EDTA disodium and 10-60% of water;

c phase component: acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer 0.05-0.5%, carbomer 0.1-0.6%, and water 10-20%;

and (3) phase D component: 1 to 8 percent of dipropylene glycol or 1.3 propanediol and 0.1 to 0.8 percent of preservative;

phase E component: 0.05-0.5% of carambola leaf extract, 0.05-0.5% of salix flexuosa extract, 0.02-0.3% of sedum sarmentosum extract, 0.01-0.1% of desert rose leaf cell extract, 0.05-0.4% of radix ophiopogonis extract, 0.05-0.5% of catalpa ovata bark/leaf extract and 0.05-0.5% of glycerylaminoethanol methacrylate/stearyl alcohol methacrylate copolymer;

and F phase component: 0.05 to 0.2 percent of sodium hydroxide and 2 to 5 percent of water;

a G phase component: 2-10% of dipropylene glycol or 1.3 propylene glycol, 2-10% of water, 0.05-0.2% of preservative and 0.1-1% of sodium di (lauramide glutamine) lysine;

phase H component: the balance of water;

the preparation method of the high-permeability moisturizing emulsion sequentially comprises the following steps:

1) soaking carbomer in phase C in advance to completely wet it for use; mixing and stirring the D-phase raw material uniformly at normal temperature for later use; dissolving the F phase at normal temperature for later use;

2) adding the raw materials of the phase B into an emulsifying pot, stirring and heating to 90-95 ℃, dissolving, then adding the raw materials of the phase C, stirring uniformly, preserving heat at 90 +/-3 ℃ for 15-20 minutes to completely defoam, cooling to 50 +/-3 ℃, then respectively adding the raw materials of the phase D and the phase E, stirring uniformly, finally adding the dissolved raw material of the phase F, stirring uniformly, cooling to 40 +/-3 ℃ for later use, and obtaining a first mixture;

3) adding the raw materials of phase A into an oil phase pot, mixing and heating to 80-85 deg.C, stirring for dissolving, and keeping the temperature at 80 + -3 deg.C for use;

4) adding the raw materials of the G phase into a water phase pot, stirring and heating to 70-75 ℃, dissolving, and keeping the temperature at 70 +/-3 ℃ for later use;

5) pumping the pretreated phase A into the water phase pot from the oil pot under the normal stirring and high-speed homogenization state of the water phase pot filled with the phase G, continuing to perform high-speed homogenization for 10-15 minutes after pumping, adding water of the phase H into the water phase pot after the homogenization is finished, stirring for 5-8 minutes, and uniformly stirring for later use to obtain a second mixture;

6) adding the second mixture into the prepared first mixture, stirring for 10-15 minutes, and stirring uniformly.

2. The high permeability moisturizing emulsion of claim 1, wherein the preservative in phase D is phenoxyethanol// ethylhexylglycerin.

3. The moisturizing emulsion of claim 1, wherein the preservative of phase G is methylparaben.

4. The preparation method of the high-permeability moisturizing emulsion as claimed in claim 1, which is characterized by sequentially comprising the following steps:

1) soaking carbomer in phase C in advance to completely wet it for use; mixing and stirring the D-phase raw material uniformly at normal temperature for later use; dissolving the F phase at normal temperature for later use;

2) adding the raw materials of the phase B into an emulsifying pot, stirring and heating to 90-95 ℃, dissolving, then adding the raw materials of the phase C, stirring uniformly, preserving heat at 90 +/-3 ℃ for 15-20 minutes to completely defoam, cooling to 50 +/-3 ℃, then respectively adding the raw materials of the phase D and the phase E, stirring uniformly, finally adding the dissolved raw material of the phase F, stirring uniformly, cooling to 40 +/-3 ℃ for later use, and obtaining a first mixture;

3) adding the raw materials of phase A into an oil phase pot, mixing and heating to 80-85 deg.C, stirring for dissolving, and keeping the temperature at 80 + -3 deg.C for use;

4) adding the raw materials of the G phase into a water phase pot, stirring and heating to 70-75 ℃, dissolving, and keeping the temperature at 70 +/-3 ℃ for later use;

5) pumping the pretreated phase A into the water phase pot from the oil pot under the normal stirring and high-speed homogenization state of the water phase pot filled with the phase G, continuing to perform high-speed homogenization for 10-15 minutes after pumping, adding water of the phase H into the water phase pot after the homogenization is finished, stirring for 5-8 minutes, and uniformly stirring for later use to obtain a second mixture;

6) adding the second mixture into the prepared first mixture, stirring for 10-15 minutes, and stirring uniformly.