CN108489787A - A kind of blood test intelligence smear machine - Google Patents
A kind of blood test intelligence smear machine Download PDFInfo
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- CN108489787A CN108489787A CN201810617313.XA CN201810617313A CN108489787A CN 108489787 A CN108489787 A CN 108489787A CN 201810617313 A CN201810617313 A CN 201810617313A CN 108489787 A CN108489787 A CN 108489787A
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- 238000009534 blood test Methods 0.000 title claims abstract description 16
- 239000011521 glass Substances 0.000 claims abstract description 79
- 210000004369 blood Anatomy 0.000 claims abstract description 58
- 239000008280 blood Substances 0.000 claims abstract description 58
- 238000003860 storage Methods 0.000 claims abstract description 45
- 238000006243 chemical reaction Methods 0.000 claims abstract description 11
- 230000007246 mechanism Effects 0.000 claims description 31
- 238000005259 measurement Methods 0.000 claims description 24
- 210000000078 claw Anatomy 0.000 claims description 16
- 241000237970 Conus <genus> Species 0.000 claims description 14
- 238000012360 testing method Methods 0.000 claims description 14
- 238000012545 processing Methods 0.000 claims description 11
- 238000005192 partition Methods 0.000 claims description 10
- 238000003825 pressing Methods 0.000 claims description 8
- 239000000696 magnetic material Substances 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 4
- 238000001179 sorption measurement Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 3
- 230000002146 bilateral effect Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 230000005611 electricity Effects 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 2
- 239000002775 capsule Substances 0.000 description 4
- 238000012864 cross contamination Methods 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 2
- 235000011613 Pinus brutia Nutrition 0.000 description 2
- 241000018646 Pinus brutia Species 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000008713 feedback mechanism Effects 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012797 qualification Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of blood test intelligence smear machines, including glass slide storage module, sample-adding module, push jack module, delivery module, control module；The present invention flows through channel to blood using X-ray emitter and is scanned, and after being received by high-resolution receiver, it is converted again through D/A conversion unit, the viscosity of the blood is finally analyzed using analytic operation unit, according to the characteristic of different blood viscosities, the angle and dynamics of push jack are revised, special parameter can be formulated to different blood, it is ensured that the success rate of smear and late detection.In short, the present invention has the advantages that smear efficiency, accuracy rate and success rate are high.
Description
Technical field
The invention belongs to the field of medical instrument technology, and in particular to a kind of blood test intelligence smear machine.
Background technology
With the progress of modern medicine, blood test becomes the conventional means for examining many diseases, and according to money
Material shows that the blood plasma and interior suspended material in blood are increasingly becoming the principal element for influencing blood sample characteristic.Other environment because
Element, such as environment temperature, humidity, storage period and preservation condition, can all influence the structure of blood film.For example, in identical smearing
Apply identical blood sample under parameter, when environment temperature is lower, blood film becomes shorter and thickness.On the contrary, working as environment temperature liter
Gao Shi, blood film become more longer thinner.
Traditional smear manufacturing process needs manual operation, it is desirable that is equably to be coated in blood on glass slide, due to being
Manual operations needs the experience by means of medical worker, and from the point of view of practice operates, it is difficult to blood be compared with smearing equal
It is even, not only heavy workload and efficiency is low, and also single success rate is also low.
Therefore occurs smearing machine in the prior art to replace manually smearing, but the smearing machine of single also compares man efficiency
Do not improve how many.And batch smearing machine is only limitted to use when the experimental demonstration of less demanding to sample, if it is as hospital
Inspection actual use, since the characteristic of the blood sample of different patients is not quite similar, all use unified smearing parameter, be bound to
It can influence the final effect of blood film.And the cross contamination for easily causing blood influences the accuracy subsequently measured.
Invention content
For the technical problem present on, the present invention provides a kind of accurately blood test intelligence smear machine.
The technical scheme is that：A kind of blood test intelligence smear machine, including glass slide storage module, sample-adding mould
Block, push jack module, delivery module, control module；
The glass slide storage module includes storage cabin, glass slide, four vertex of the glass slide accompany respectively by
Glass slide clamp made of magnetic material, and stack in the storage cabin up and down, the lower port of storage cabin is equipped with electric controlled door, for controlling
System release glass slide；
The sample-adding module includes test tube turntable mounting, viscosity measurement device, manipulator, and the viscosity measurement device setting is carrying glass
The longitudinal central position on the right side of piece storage module, viscosity measurement device is equipped with through hole, and the side of through hole is equipped with X-ray
The other side of device, through hole is equipped with the high-resolution receiver opposite with X-ray emitter, and the bottom of viscosity measurement device is embedded with
Camera one, for monitoring whether blood drips to glass slide, the test tube turntable mounting is fixed on the top of viscosity measurement device, examination
Funnel containing blood to be measured is housed, the manipulator is fixed at the top of viscosity measurement device, is used for the funnel in pipe turntable mounting
Fold up or press from both sides out the through hole；
The push jack module includes horizontal support, pressurization telescopic rod, push jack, miniature steering engine, push jack set removal mechanism, push jack
Set replaces mechanism, sliding block, electric reciprocating push rod, and the horizontal support is arranged in the right side of sample-adding module, the pressurization telescopic rod
It is vertically connected on the leading flank of horizontal support by the sliding block, the electric reciprocating push rod is fixed on the right side of horizontal support
End, and end is fixedly linked with sliding block, for driving sliding block, transversely holder carries out bilateral reciprocation, and then drives push jack pair
Blood carries out smear processing, and the bottom of the sliding block is equipped with camera two, the lower end of the rear end and pressurization telescopic rod of the push jack
It is flexibly connected by rotation axis, the front end sleeve of push jack once property push jack set can prevent cross contamination, improve the accurate of measurement
Degree, the output shaft of the miniature steering engine are connected with one end of the rotation axis, the rotational angle for adjusting push jack, the push jack
Set removal mechanism is detachably connected below the left end of horizontal support, and the push jack set replaces mechanism and is detachably connected on lateral branch
Below the right end of frame；
The delivery module includes horizontal electric conveyer, magnetic block, and the horizontal electric conveyer is deposited positioned at glass slide
The lower section of module, sample-adding module, push jack module is store, the magnetic block is arranged in the inside of horizontal electric conveyer, for glass
Piece folder provides adsorption capacity；
The control module includes servo drive unit, image processing unit, D/A conversion unit, analytic operation unit,
The running that the servo drive unit is used to control glass slide storage module, be loaded module, push jack module, delivery module；It is described
The picture that image processing unit is used to handle the camera one, camera two is shot；The D/A conversion unit is used for institute
It states high-resolution receiver and receives X-ray information and be converted into data；The analytic operation unit is used for the picture sum number
According to progress analytic operation, and feeds back to servo drive unit according to result and carry out instruction adjustment.
Further, the bottom of the conus portion of the funnel is equipped with miniature one-way pressure valve, the upper end of the pipe section of funnel
Equipped with hollow sacculus, the hollow sacculus is communicated with the miniature one-way pressure valve upwards, is communicated with outside atmosphere downwards, described
Conus portion upper end is equipped with sealing cover, and in the case of miniature one-way pressure valve is for ensureing external force again, the blood inside funnel will not leak
It spills, hollow sacculus is used for after being squeezed release by external force, and inside forms the negative pressure cavity relative to conus portion, is opened with this micro-
Type one-way pressure valve so that the blood in conus portion flows into hollow ball capsule and cached, then makes blood pass through pipe section and fall into load
On slide.
Further, the top of the viscosity measurement device is equipped with pressing mechanism, and the pressing mechanism includes electric telescopic rod
One, relative level is arranged at the both ends of through hole respectively for electric telescopic rod two, the electric telescopic rod one and electric telescopic rod two,
And be electrically connected with the servo drive unit, electric telescopic rod one and electric telescopic rod two are used to provide extruding to hollow sacculus
External force forms it into negative pressure cavity.
Further, the push jack set removal mechanism includes receiving box and micromachine claw, the micromachine claw
It is fixed on the madial wall at the top of the reception box, and is open towards the push jack, micromachine claw and the servo-drive
Unit is electrically connected, and micromachine claw extracts the push jack set being set on push jack, then makes it automatic after being unclamped to it
It falls into and receives in box.
Further, it includes the storage box, partition board and compressed spring that the push jack set, which replaces mechanism, and the compressed spring is longitudinal
It is fixed on the interior bottom of the storage box, the partition board is fixedly connected on the upper end of the compressed spring, is placed on partition board
Push jack set is stated, the top of the storage box is equipped with outlet, and the outlet is equal to a push jack towards the push jack, the height of outlet
The thickness of set utilizes the elastic force of compressed spring so that exit has push jack set to wait for position always.
Further, the storage cabin is internally provided with temp controlling heater, the temp controlling heater and the servo-drive
Unit is electrically connected, and temp controlling heater is used to carry out heated at constant temperature to glass slide, it is made to have initial temperature, is conducive to improve painting
The success rate of piece.
Further, the camera two is 180 degree wide-angle camera, the removal that can have not only been covered to left redundant push jack, but also
The replacement that can be covered to right redundant push jack can also monitor downwards the position of push jack and blood, and determine that smear terminates.
Further, the electric controlled door is electrically connected with the servo drive unit, including internal control door and external control door, described
Internal control door is arranged in the top of external control door, and the distance between internal control door and external control door are equal to the thickness of the glass slide clamp, internal control
Door is interposed between bottom glass slide and its top glass slide, can guarantee that the glass slide of only bottommost passes through when external control door is opened
Magnetic glass slide clamp is adsorbed on the belt of horizontal electric conveyer, if without internal control door, is probably had more
A glass slide is adsorbed.
The present invention working method be：
The first step, respectively four vertex of the glass slide folder on the glass slide clamp made of magnetic material, and by its
It stacks in the storage cabin up and down, it is 25-30 DEG C to open the temp controlling heater setting temperature, heating and thermal insulation 20-30min；
Second step, the servo drive unit control the internal control door be inserted in bottom glass slide and its top glass slide it
Between, external control door opening is then controlled again so that the related glass slide of glass slide clamp is attracted on the belt of horizontal electric conveyer,
Simultaneously close off external control door；
Third walks, and the manipulator removes a funnel from the test tube turntable mounting, its pipe section is run through from described
The upper end in hole is inserted into；The rotation of horizontal electric conveyer is driven by the servo drive unit, when the front of glass slide reaches leakage
When bucket lower section, and image processing unit is fed back to according to the monitoring of the camera one, then by analytic operation unit calculate away from
From rear, the servo drive unit is fed back to, suspends the movement of horizontal electric conveyer；
4th step, the electric telescopic rod one, electric telescopic rod two are directed at the hollow sacculus and carry out pine after extruding 1-2s
It opens, forms it into negative pressure cavity, miniature one-way pressure valve is opened with this so that the blood in conus portion flows into hollow ball capsule and carries out
Caching, then so that blood is passed through pipe section and fall on glass slide；When blood passes through pipe section, the X-ray emitter to its into
Row scanning, the high-resolution receiver are transmitted to the D/A conversion unit after receiving scanning signal, convert a signal into
Data, then the viscosity of blood is analyzed by the analytic operation unit with this, and the information of blood viscosity is fed back into servo and is driven
Moving cell, angle and pressure for revising push jack in push jack module；
5th step feeds back to servo again by feedback mechanism and drives after camera one monitors to have drop of blood on glass slide
Moving cell makes it be again started up horizontal electric conveyer and is moved, until the camera two detects that glass slide moves to
The underface of push jack stops again；
6th step, the pressurization telescopic rod drives push jack to bounce back to peak upwards, and the miniature steering engine passes through institute
It states rotation axis and rotates push jack horizontal 90-degree to the right, under the drive of electric reciprocating push rod and under the positioning of camera two, push jack
The outlet entrance for replacing mechanism is covered from push jack, wears push jack set backed off after random, it is miniature again under the location navigation of camera two
Steering engine is rotated according to the angle that step 4 is set, until touching drop of blood, pressurization telescopic rod is applied according to setting pressure
Pressure, under the promotion of electric reciprocating push rod, is moved to the left, and terminates after camera two monitors completely clearly head body tail shape
Smear；Pressurization telescopic rod drives push jack to bounce back to peak upwards again, and the miniature steering engine is revolved by the rotation axis
Turn push jack horizontal 90-degree to the left, under the drive of electric reciprocating push rod and under the positioning of camera two, with using push jack
The push jack of set is directed at the micromachine claw, and push jack set was used using the removal of micromachine claw；
7th step removes the glass slide after the completion of smear, and repeats above-mentioned one to six step, until smear terminates.
Compared with prior art, beneficial effects of the present invention are：
(1) during pipeline flows, the present invention is scanned it using X-ray emitter blood, and passes through height
It after resolution ratio receiver receives, then is converted through D/A conversion unit, finally analyzes the blood using analytic operation unit
Viscosity the angle and dynamics of push jack are revised according to the characteristic of different blood viscosities, can to different blood formulate special parameter,
Ensure the success rate of smear and late detection；
(2) integration that funnel of the invention can realize blood access and be added dropwise, wherein miniature one-way pressure valve is used for
In the case of ensureing external force again, the blood inside funnel, which will not leak, to be spilt, and hollow sacculus is used for after being squeezed release by external force, internal
The negative pressure cavity relative to conus portion is formed, miniature one-way pressure valve is opened with this so that the blood in conus portion flows into hollow
Sacculus is cached, then so that blood is passed through pipe section and fallen on glass slide；The trouble being manually added dropwise and inaccuracy are avoided, is independently set
Meter can avoid the cross contamination of blood；
(3) push jack of the invention is equipped with disposable push jack set, and can be under automation mechanized operation, self-service completion push jack
The removal and replacement operation of set, also for the cross contamination for avoiding blood；
(4) of the invention horizontal electric conveyer is internally provided with magnetic block, can be every belt to the glass as magnetic material
Piece folder provides adsorption capacity, and then fixed glass slide prevents it to be subjected to displacement during smear；
(5) temp controlling heater in storage cabin of the invention makes it have initial temperature for carrying out heated at constant temperature to glass slide
Degree is conducive to the success rate for improving smear.
In short, the present invention has the advantages that smear efficiency, accuracy rate and success rate are high.
Description of the drawings
Fig. 1 is the glass slide storage module of the present invention, sample-adding module, push jack module and delivery module structural schematic diagram；
Fig. 2 is the system block diagram of the present invention；
Fig. 3 is the sectional view of the push jack set removal mechanism of the present invention；
Fig. 4 is that the push jack set of the present invention replaces the sectional view of mechanism.
Wherein, 1- glass slides storage module, 10- storage cabins, 100- temp controlling heaters, 11- glass slides, 12- glass slide clamps,
13- electric controlled doors, 130- internal controls door, 131- external controls door, 2- sample-addings module, 20- test tubes turntable mounting, 21- viscosity measurements device, 210- are squeezed
Press mechanism, 211- electric telescopic rods one, 212- electric telescopic rods two, 22- manipulators, 23- through holes, 24-X ray generators,
25- high-resolution receiver, 26- cameras one, 27- funnels, 27a- conus portions, 27b- pipe sections, the miniature uniaxial pressures of 270-
The hollow sacculus of valve, 271-, 272- sealing covers, 3- push jacks module, 30- horizontal supports, 31- pressurizations telescopic rod, 32- push jacks, 33- are micro-
Type steering engine, 34- push jacks set removal mechanism, 340- receive box, 341- micromachines claw, 35- push jacks set replacement mechanism, 350- and deposit
Storage box, 351- partition boards, 352- compressed springs, the outlets 353-, 36- sliding blocks, 37- electric reciprocatings push rod, 38- cameras two, 39- turn
Moving axis, 310- push jacks set, 4- delivery modules, 40- horizontal electrics conveyer, 41- magnetic blocks, 5- control modules, 50- servo-drives
Unit, 51- image processing units, 52- D/A conversion units, 53- analytic operation units.
Specific implementation mode
Below by the preferably embodiment of the present invention, to be illustrated to the specific implementation mode of the present invention,
But the implementation and protection of the present invention are without being limited thereto.
As shown in Fig. 2, a kind of blood test intelligence smear machine, including glass slide storage module 1, sample-adding module 2, push jack mould
Block 3, delivery module 4, control module 5；
As shown in Figure 1, glass slide storage module 1 includes storage cabin 10, glass slide 11, four apex angles punishment of glass slide 11
Glass slide clamp 12 made of magnetic material are not accompanied, and are stacked in storage cabin 10 up and down, and the lower port of storage cabin 10 is equipped with electricity
Door 13 is controlled, for controlling release glass slide 11；As shown in Figure 1, electric controlled door 13 is electrically connected with servo drive unit 50, including it is interior
Control door 130 and external control door 131, internal control door 130 are arranged in the top of external control door 131, and between internal control door 130 and external control door 131
Distance be equal to the thickness of glass slide clamp 12, internal control door 130 is interposed between bottom glass slide 11 and its top glass slide 11, works as external control
It can guarantee that the glass slide 11 of only bottommost is adsorbed to horizontal electric transmission by magnetic glass slide clamp 12 when door 131 is opened
On the belt of machine 40, if without internal control door 130, probably has multiple glass slides 11 and adsorbed.Storage cabin 10 it is interior
Portion is equipped with temp controlling heater 100, and temp controlling heater 100 and servo drive unit 50 are electrically connected, temp controlling heater 100 for pair
Glass slide 11 carries out heated at constant temperature, it is made to have initial temperature, is conducive to the success rate for improving smear.
As shown in Figure 1, sample-adding module 2 includes test tube turntable mounting 20, viscosity measurement device 21, manipulator 22, viscosity measurement device
21 are arranged on the right side of glass slide storage module 1, and the longitudinal central position of viscosity measurement device 21 is equipped with through hole 23, through hole 23
Side be equipped with X-ray emitter 24, the other side of through hole 23 is equipped with the high-resolution opposite with X-ray emitter 24 and receives
The bottom of device 25, viscosity measurement device 21 is embedded with camera 1, and for monitoring whether blood drips to glass slide 11, test tube turns
Plate rail 20 is fixed on the top of viscosity measurement device 21, and the funnel 27 containing blood to be measured, manipulator 22 are housed in test tube turntable mounting 20
It is fixed on 21 top of viscosity measurement device, for folding up or pressing from both sides out through hole 23 by funnel 27；As shown in Figure 1, the circular cone of funnel 27
The bottom of portion 27a is equipped with miniature one-way pressure valve 270, and the upper end of the pipe section 27b of funnel 27 is equipped with hollow sacculus 271, hollow
Sacculus 271 is communicated with miniature one-way pressure valve 270 upwards, is communicated with outside atmosphere downwards, and the upper ends conus portion 27a are equipped with sealing cover
272, in the case of miniature one-way pressure valve 270 is for ensureing external force again, the blood inside funnel 27, which will not leak, to be spilt, hollow sacculus
271 for after being squeezed release by external force, inside to form the negative pressure cavity relative to conus portion 27a, and miniature list is opened with this
To pressure valve 270 so that the blood in conus portion 27a flows into hollow ball capsule 271 and cached, then blood is made to pass through pipe section
27b is fallen on glass slide 11.As shown in Figure 1, the top of viscosity measurement device 21 is equipped with pressing mechanism 210, pressing mechanism 210 includes
Electric telescopic rod 1, electric telescopic rod 2 212, electric telescopic rod 1 and electric telescopic rod 2 212 distinguish relative level
It is arranged at the both ends of through hole 23, and is electrically connected with servo drive unit 50, electric telescopic rod 1 and electric telescopic rod two
212 squeeze external force for providing hollow sacculus 271, form it into negative pressure cavity.
As shown in Figure 1, push jack module 3 includes horizontal support 30, pressurization telescopic rod 31, push jack 32, miniature steering engine 33, push jack
Removal mechanism 34, push jack set replacement mechanism 35, sliding block 36, electric reciprocating push rod 37 are covered, the setting of horizontal support 30 is in sample-adding module 2
Right side, pressurization telescopic rod 31 is vertically connected to by sliding block 36 on the leading flank of horizontal support 30, and electric reciprocating push rod 37 is solid
It is scheduled on the right end of horizontal support 30, and end is fixedly linked with sliding block 36, transversely holder 30 carries out a left side for driving sliding block 36
Right reciprocating motion, and then push jack 32 is driven to carry out smear processing to blood, the bottom of sliding block 36 is equipped with camera 2 38, camera
2 38 be 180 degree wide-angle camera, 310 removal can have not only been covered to left redundant push jack, but also can cover 310 to right redundant push jack
It replaces, the position of push jack 32 and blood can also be monitored downwards, and determine that smear terminates.The rear end of push jack 32 is flexible with pressurization
The lower end of bar 31 is flexibly connected by rotation axis 39, and once property push jack covers 310 to the front end sleeve of push jack 32, can prevent from intersecting dirty
Dye, improves the precision of measurement, and the output shaft of miniature steering engine 33 is connected with one end of rotation axis 39, for adjusting turning for push jack 32
Dynamic angle, push jack set removal mechanism 34 is detachably connected on 30 lower section of left end of horizontal support, as shown in figure 3, push jack set removal
Mechanism 34 includes receiving box 340 and micromachine claw 341, and micromachine claw 341 is fixed on the inside for receiving 340 top of box
It on wall, and is open towards push jack 32, micromachine claw 341 is electrically connected with servo drive unit 50, micromachine claw 341
The push jack set 310 being set on push jack 32 is extractd, then automatically falls into it after being unclamped to it and receives in box 340.Push jack
Set is replaced mechanism 35 and is detachably connected below the right end of horizontal support 30；As shown in figure 4, it includes depositing that push jack set, which replaces mechanism 35,
Storage box 350, partition board 351 and compressed spring 352, compressed spring 352 are vertically fixed in the interior bottom of the storage box 350, and partition board 351 is solid
Surely it is connected to the upper end of compressed spring 352, push jack set 310 is placed on partition board 351, the top of the storage box 350 is equipped with outlet
353, towards push jack 32, the height for exporting 353 is equal to the thickness that a push jack covers 310, utilizes compressed spring 352 for outlet 353
Elastic force so that there is push jack set 310 to wait for position at outlet 353 always.
As shown in Figure 1, delivery module 4 includes horizontal electric conveyer 40, magnetic block 41, horizontal electric conveyer 40 is located at
The lower section of glass slide storage module 1, sample-adding module 2, push jack module 3, magnetic block 41 are arranged in horizontal electric conveyer 40
Portion, for providing adsorption capacity to glass slide clamp 12；
As shown in Fig. 2, control module 5 include servo drive unit 50, image processing unit 51, D/A conversion unit 52,
Analytic operation unit 53, servo drive unit 50 is for controlling glass slide storage module 1, sample-adding module 2, push jack module 3, transmission
The running of module 4；The picture that image processing unit 51 is used to handle camera 1, camera 2 38 is shot；Digital-to-analogue conversion list
Member 52 is converted into data for high-resolution receiver 25 to be received X-ray information；Analytic operation unit 53 is used for picture
Analytic operation is carried out with data, and feeds back to servo drive unit 50 according to result and carries out instruction adjustment.
The working method of the present embodiment is：
The first step, respectively four vertex of glass slide 11 folder on glass slide clamp 12 made of magnetic material, and by its
It stacks in storage cabin 10 up and down, it is 28 DEG C to open temp controlling heater 100 temperature is arranged, heating and thermal insulation 25min；
Second step, servo drive unit 50 control internal control door 130 and are inserted in bottom glass slide 11 and its top glass slide 11
Between, the opening of external control door 131 is then controlled again so that 12 related glass slide 11 of glass slide clamp is attracted to horizontal electric conveyer
On 40 belt, external control door 131 is simultaneously closed off；
Third walks, and manipulator 22 removes a funnel 27 from test tube turntable mounting 20, by its pipe section 27b from through hole 23
Upper end be inserted into；Horizontal electric conveyer 40 is driven to rotate by servo drive unit 50, when the front of glass slide 11 reaches leakage
Struggle against 27 lower section when, and image processing unit 51 is fed back to according to the monitoring of camera 1, then pass through analytic operation unit 53 and count
After calculating distance, servo drive unit 50, the movement of pause horizontal electric conveyer 40 are fed back to；
4th step, electric telescopic rod 1, electric telescopic rod 2 212 are directed at hollow sacculus 271 and carry out pine after extruding 1-2s
It opens, forms it into negative pressure cavity, miniature one-way pressure valve 270 is opened with this so that the blood in conus portion 27a flows into hollow ball
Capsule 271 is cached, then so that blood is passed through pipe section 27b and fallen on glass slide 11；When blood is by pipe section 27b, X-ray
Generator 24 is scanned it, and high-resolution receiver 25 is transmitted to D/A conversion unit 52 after receiving scanning signal, will
Signal is converted to data, then analyzes the viscosity of blood with this by analytic operation unit 53, and the information of blood viscosity is fed back
To servo drive unit 50, angle and pressure for revising push jack 32 in push jack module 3；
5th step feeds back to again by feedback mechanism and watches after camera 1 monitors to have drop of blood on glass slide 11
Driving unit 50 is taken, so that it is again started up horizontal electric conveyer 40 and is moved, until camera 2 38 detects glass slide
11 underfaces for moving to push jack 32 stop again；
6th step, pressurization telescopic rod 31 drives push jack 32 to bounce back to peak upwards, and miniature steering engine 33 passes through rotation
Axis 39 rotates the horizontal 90-degree to the right of push jack 32, under the drive of electric reciprocating push rod 37 and under the positioning of camera 2 38, push jack 32
The entrance of outlet 353 for replacing mechanism 35 is covered from push jack, is worn push jack and is covered 310 backed off after random, again in the positioning of camera 2 38
Under navigation, miniature steering engine 33 is rotated according to the angle that step 4 is set, until touch drop of blood, pressurization telescopic rod 31 according to
Setting pressure presses, and under the promotion of electric reciprocating push rod 37, is moved to the left, when camera 2 38 monitors completely clearly
Head body tail shape after terminate smear；Pressurization telescopic rod 31 drives push jack 32 to bounce back to peak, and miniature rudder upwards again
Machine 33 rotates the horizontal 90-degree to the left of push jack 32 by rotation axis 39, and under the drive of electric reciprocating push rod 37 and camera 2 38 is determined
Under position, with using the push jack 32 of push jack set 310 to be directed at micromachine claw 341, made using the removal of micromachine claw 341
Used push jack set 310；
7th step removes the glass slide 11 after the completion of smear, and repeats above-mentioned one to six step, until smear terminates.
Compliance test result：
Experimental subjects：100 are taken to wait for that smear blood sample, each sample are divided into 3 equal portions, using embodiment group, control group
Smear operation is carried out to this 100 samples respectively with reference to group, wherein embodiment group blood smear device using the present invention, it is right
According to a group blood smear device of use Publication No. CN207488042U, artificial smear optimal Template is chosen as experimental group with reference to group
Comparison with control group refers to.
Experimental method：1) comparative example group, control group are fully completed the smear operating time by way of timing；2) lead to
It crosses artificial observation method to evaluate embodiment group, the apparent of the smear sample of control group, the apparent person of head body tail is qualification, on the contrary
It is unqualified；3) testing result of embodiment group, the smear testing result of control group and reference group is compared, comparation and assessment are accurate
Rate.
Experimental result：As shown in table 1：
Table 1：Embodiment group, control group, the experimental result with reference to group
As shown in Table 1, blood smear device of the invention is more efficient, and qualification rate is 100%, and accuracy rate is also up to
99.5%.
Finally it should be noted that：The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although
Present invention has been described in detail with reference to the aforementioned embodiments, it will be understood by those of ordinary skill in the art that：It still may be used
To modify to the technical solution recorded in previous embodiment or equivalent replacement of some of the technical features；And
These modifications or replacements, the spirit and model of technical solution of the embodiment of the present invention that it does not separate the essence of the corresponding technical solution
It encloses.
Claims (8)
1. a kind of blood test intelligence smear machine, which is characterized in that including glass slide storage module (1), sample-adding module (2), push away
Piece module (3), delivery module (4), control module (5)；
The glass slide storage module (1) includes storage cabin (10), glass slide (11), four vertex of the glass slide (11)
The glass slide clamp made of magnetic material (12) is accompanied respectively, and is stacked in the storage cabin (10) up and down, storage cabin (10)
Lower port is equipped with electric controlled door (13)；
The sample-adding module (2) includes test tube turntable mounting (20), viscosity measurement device (21), manipulator (22), the viscosity measurement
Device (21) setting is equipped with through hole in the right side of glass slide storage module (1), the longitudinal central position of viscosity measurement device (21)
(23), the side of through hole (23) is equipped with X-ray emitter (24), and the other side of through hole (23) is equipped with and X-ray emitter
(24) bottom of opposite high-resolution receiver (25), viscosity measurement device (21) is embedded with camera one (26), the test tube
Turntable mounting (20) is fixed on the top of viscosity measurement device (21), and the funnel containing blood to be measured is housed in test tube turntable mounting (20)
(27), the manipulator (22) is fixed at the top of viscosity measurement device (21), described for folding up or pressing from both sides out by the funnel (27)
Through hole (23)；
The push jack module (3) includes horizontal support (30), pressurization telescopic rod (31), push jack (32), miniature steering engine (33), push jack
Cover removal mechanism (34), push jack set replaces mechanism (35), sliding block (36), electric reciprocating push rod (37), the horizontal support (30)
It is arranged on the right side of sample-adding module (2), the pressurization telescopic rod (31) is vertically connected to horizontal support by the sliding block (36)
(30) on leading flank, the electric reciprocating push rod (37) is fixed on the right end of horizontal support (30), and end and sliding block (36)
It is fixedly linked, for driving sliding block (36), transversely holder (30) carries out bilateral reciprocation, and the bottom of the sliding block (36) is set
There are camera two (38), the rear end of the push jack (32) to connect by rotation axis (39) activity with the lower end of pressurization telescopic rod (31)
It connects, the front end sleeve of push jack (32) once property push jack set (310), output shaft and the rotation axis of the miniature steering engine (33)
(39) one end is connected, the rotational angle for adjusting push jack (32), and the push jack set removal mechanism (34) is detachably connected on
Below the left end (30) of horizontal support, the push jack set is replaced mechanism (35) and is detachably connected under the right end of horizontal support (30)
Side；
The delivery module (4) includes horizontal electric conveyer (40), magnetic block (41), horizontal electric conveyer (40) position
In glass slide storage module (1), the lower section of sample-adding module (2), push jack module (3), magnetic block (41) setting is in horizontal electricity
The inside of dynamic conveyer (40), for providing adsorption capacity to glass slide clamp (12)；
The control module (5) includes servo drive unit (50), image processing unit (51), D/A conversion unit (52), divides
Arithmetic element (53) is analysed, the servo drive unit (50) is for controlling glass slide storage module (1), sample-adding module (2), push jack
The running of module (3), delivery module (4)；Described image processing unit (51) is for handling the camera one (26), camera
The picture of two (38) shooting；The D/A conversion unit (52) is used to the high-resolution receiver (25) receiving X-ray
Information is converted into data；The analytic operation unit (53) is used to carry out analytic operation to the picture and data, and according to knot
Fruit feeds back to servo drive unit (50) and carries out instruction adjustment.
2. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the conus portion of the funnel (27)
The bottom of (27a) is equipped with miniature one-way pressure valve (270), and the upper end of the pipe section (27b) of funnel (27) is equipped with hollow sacculus
(271), the hollow sacculus (271) communicates with the miniature one-way pressure valve (270) upwards, is communicated with outside atmosphere downwards,
Conus portion (27a) upper end is equipped with sealing cover (272).
3. a kind of blood test intelligence smear machine as claimed in claim 2, which is characterized in that the viscosity measurement device (21)
Top is equipped with pressing mechanism (210), and the pressing mechanism (210) includes electric telescopic rod one (211), electric telescopic rod two
(212), relative level is arranged in through hole (23) respectively for the electric telescopic rod one (211) and electric telescopic rod two (212)
Both ends, and be electrically connected with the servo drive unit (50).
4. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the push jack covers removal mechanism
(34) include that reception box (340) and micromachine claw (341), the micromachine claw (341) are fixed on the reception box
(340) it on the madial wall at the top of, and is open towards the push jack (32), micromachine claw (341) and the servo-drive list
First (50) are electrically connected.
5. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the push jack set replaces mechanism
(35) include the storage box (350), partition board (351) and compressed spring (352), the compressed spring (352) is vertically fixed in described
The interior bottom of the storage box (350), the partition board (351) are fixedly connected on the upper end of the compressed spring (352), partition board (351)
On be placed with the push jack set (310), the top of the storage box (350) is equipped with outlet (353), described outlet (353) direction
The push jack (32), the height of outlet (353) are equal to the thickness of a push jack set (310).
6. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the inside of the storage cabin (10)
Equipped with temp controlling heater (100), the temp controlling heater (100) is electrically connected with the servo drive unit (50).
7. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the inside of the storage cabin (10)
Equipped with temp controlling heater (100), for heating glass slide (11).
8. a kind of blood test intelligence smear machine as described in claim 1, which is characterized in that the camera two (38) is
180 degree wide-angle camera.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810617313.XA CN108489787B (en) | 2018-06-15 | 2018-06-15 | Blood test intelligence smear ware |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810617313.XA CN108489787B (en) | 2018-06-15 | 2018-06-15 | Blood test intelligence smear ware |
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| CN108489787A true CN108489787A (en) | 2018-09-04 |
| CN108489787B CN108489787B (en) | 2020-08-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810617313.XA Expired - Fee Related CN108489787B (en) | 2018-06-15 | 2018-06-15 | Blood test intelligence smear ware |
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| CN109668763A (en) * | 2019-01-03 | 2019-04-23 | 桂林优利特医疗电子有限公司 | A kind of blood pushing piece auto-feeder |
| CN111551418A (en) * | 2020-04-01 | 2020-08-18 | 郑州中普医疗器械有限公司 | Slide pusher |
| WO2021102984A1 (en) * | 2019-11-29 | 2021-06-03 | 深圳迈瑞生物医疗电子股份有限公司 | Smear preparation device, and sample analysis system and method |
| CN114076699A (en) * | 2020-08-14 | 2022-02-22 | 爱威科技股份有限公司 | Blood push sheet manufacturing device |
| CN115144247A (en) * | 2022-09-02 | 2022-10-04 | 深圳明灏生物科技有限公司 | Smear device for liquid-based thin-layer cell detection |
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| CN108489787B (en) | 2020-08-04 |
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