CN114646524A - Blending device and sample analyzer - Google Patents

Blending device and sample analyzer Download PDF

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Publication number
CN114646524A
CN114646524A CN202011503080.4A CN202011503080A CN114646524A CN 114646524 A CN114646524 A CN 114646524A CN 202011503080 A CN202011503080 A CN 202011503080A CN 114646524 A CN114646524 A CN 114646524A
Authority
CN
China
Prior art keywords
gripper
test tube
assembly
mixing
sampling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011503080.4A
Other languages
Chinese (zh)
Inventor
张勇
邹云平
甘小锋
于记良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Dymind Biotechnology Co Ltd
Original Assignee
Shenzhen Dymind Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Dymind Biotechnology Co Ltd filed Critical Shenzhen Dymind Biotechnology Co Ltd
Priority to CN202011503080.4A priority Critical patent/CN114646524A/en
Priority to PCT/CN2021/119384 priority patent/WO2022127247A1/en
Publication of CN114646524A publication Critical patent/CN114646524A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/42Clamping or holding arrangements for mounting receptacles on mixing devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements

Abstract

The application provides a mixing device, this mixing device includes tongs subassembly and actuating mechanism. The gripper assembly comprises a first driving mechanism, a first gripper and a second gripper. The first driving mechanism comprises a first transmission piece and a second transmission piece which can perform relative opening and closing movement, the first gripper is connected with the first transmission piece, and the second gripper is connected with the second transmission piece and arranged at an interval relative to the first gripper. The rotating mechanism is used for driving the device to perform blending action. In this way, the mixing device that this application provided has avoided getting the test tube from a direction clamp, gets the in-process at the clamp, when the test tube label did not paste, the mode of the test tube of snatching of the motion of opening and shutting can prevent to destroy the test tube label. Simultaneously, when getting the test tube from the injector clamp, the mode of the test tube that snatchs of the motion of opening and shutting does not have obvious effort to the test-tube rack, need not to set up spacing piece that blocks on test-tube rack both sides, has simplified the structural design of injector.

Description

Blending device and sample analyzer
Technical Field
The application relates to the technical field of biomedical equipment, in particular to a blending device and a sample analyzer.
Background
In the field of modern medical technology, because blood detection and analysis provide many references for experimental indexes, which can play a crucial role in disease analysis and diagnosis, a sample analyzer with blood detection is one of the most widely used instruments for clinical examination in hospitals. In blood detection and analysis, blood layering can make the testing result inaccurate, consequently for the accuracy and the stability of guaranteeing the testing result, before drawing the chemical examination to the blood sample in vitro, need carry out abundant mixing to the blood in vitro. In the prior art, a blending gripper of a sample analyzer grips a test tube on a test tube rack or a test tube base support by virtue of a spring or elastic deformation of the gripper to perform blending operation, so that a certain acting force is exerted on the test tube rack, the test tube is possibly damaged in the elastic clamping process, and when a bar code on the test tube is loosened, the bar code is easily damaged; when getting the test tube from the injector clamp moreover, the injector need set up the structure of carrying on spacingly or retraining to the test tube, causes overall structure complicacy.
Disclosure of Invention
The application provides a mixing device to solve among the prior art that the clamp gets the process and damages the test tube easily, destroy the test tube bar code and need design limit stop and cause the technical problem that the injector structure is complicated.
In order to solve the technical problem, the application adopts a technical scheme that: providing a blending device, the blending device includes:
a gripper assembly comprising a first drive mechanism, a first gripper, and a second gripper;
the first driving mechanism comprises a first transmission piece and a second transmission piece which can perform relative opening and closing movement;
the first handle is connected with the first transmission piece;
the second gripper is connected with the second transmission piece and is arranged opposite to the first gripper at intervals;
and the rotating mechanism is used for driving the gripper assembly to perform uniform mixing action. According to a specific embodiment of the present application, the first driving mechanism further comprises:
a cylinder body;
the first sliding rail is arranged on the cylinder body, the first transmission part and the second transmission part are arranged on the two first sliding blocks on the sliding rail in a sliding mode, the first gripper and the second gripper are connected with the two first sliding blocks respectively, and under the driving of the cylinder body, the two first sliding blocks correspondingly move in an opening and closing mode to drive the first gripper and the second gripper to move in an opening and closing mode to grip a test tube.
According to a specific embodiment of this application, first tongs and/or the second tongs is equipped with presses along portion, first tongs and/or when second tongs snatch the test tube press along the position in the test tube directly over.
According to a specific embodiment of this application, still be equipped with air pipe connector and trachea support on the cylinder body, trachea support be used for supplementary fixed with the trachea that air pipe connector connects.
According to a specific embodiment of the present application, the first driving mechanism includes:
a first bracket;
a plurality of first pulleys mounted based on the first bracket;
the first synchronous belt comprises a first belt body section and a second belt body section which are horizontally arranged at intervals, and the first transmission piece and the second transmission piece are respectively connected to the first belt body section and the second belt body section;
and the telescopic cylinder is arranged on the first support and used for driving the first transmission piece and the second transmission piece to move in an opening and closing manner.
According to a specific embodiment of this application, first synchronous belt is still including the third area body section that is vertical setting, telescopic cylinder include with the vertical cylinder body that first support is connected and through the connecting piece with the vertical cylinder pole that the third area body section is connected, vertical cylinder pole is relative drive when vertical cylinder body is flexible first area body section with the motion of second area body section and then drive first driving medium the second driving medium carries out the motion of opening and shutting.
According to a specific embodiment of the present application, the first driving mechanism includes:
a second bracket;
two second pulleys mounted based on the second bracket;
the second synchronous belt comprises a first belt body section and a second belt body section which are horizontally arranged at intervals, and the first transmission piece and the second transmission piece are respectively connected to the first belt body section and the second belt body section;
and the screw rod motor is arranged on the second support and used for driving the first transmission piece and the second transmission piece to open and close.
According to a specific embodiment of the present application, the first driving mechanism further includes a lead screw nut seat, and the lead screw nut seat is in threaded engagement with the lead screw motor and is connected to the first belt section.
According to a specific embodiment of this application, rotary mechanism with tongs subassembly is connected for the drive tongs subassembly carries out rotatory swing, rotary mechanism includes:
mounting a plate;
a third synchronous belt;
a rotating motor mounted based on the mounting plate;
the rotating motor drives the gripper assembly to rotate and swing through a third synchronous belt.
According to a specific embodiment of this application, rotary mechanism is including locating opto-coupler and limit baffle on the mounting panel, first actuating mechanism still be equipped with the piece that is in the light that the opto-coupler corresponds, the rotating electrical machines is used for the drive first actuating mechanism swings between vertical direction and preset angle, limit baffle with the piece that is in the light constitutes the mechanical spacing of antiport, or limit baffle with the tongs subassembly constitutes the mechanical spacing of the constitution antiport.
According to a specific embodiment of this application, mixing device still includes elevating system, elevating system with rotary mechanism connects, is used for the drive rotary mechanism with tongs subassembly is whole to go up and down, elevating system includes:
a housing;
a lift motor mounted based on the housing;
and the fourth synchronous belt is driven to rotate by the lifting motor so as to drive the rotating mechanism and the gripper assembly to integrally do lifting motion.
In order to solve the technical problem, the application adopts a technical scheme that: providing a blending method, wherein the blending method is executed based on the blending device, the blending device further comprises a control assembly in communication connection with the hand grip assembly and the rotating mechanism, and the method comprises the following steps:
the control assembly controls the gripper assembly to grip the test tube;
the control assembly controls the rotating mechanism to drive the gripper assembly to swing back and forth within a preset angle range so as to perform test tube mixing action. In order to solve the technical problem, the application adopts a technical scheme that: providing a sample analyzer, wherein the sample analyzer comprises the blending device, a relay assembly and a control assembly;
the control assembly controls the gripper assembly to grip the test tube;
the control assembly controls the rotating mechanism to drive the gripper assembly to swing back and forth within a preset angle range so as to perform test tube mixing operation;
and the control component controls the relay component to send the uniformly mixed test tube into a sampling position in the sample analyzer.
According to a specific embodiment of this application, sample analysis appearance still includes the appearance subassembly of advancing that has first transfer path, the relaying subassembly has with the second transfer path that first transfer path formed the contained angle.
According to a specific embodiment of the present application, the sample analyzer includes a sampling assembly having a third transport path, and the relay assembly has a second transport path forming an angle with the third transport path.
In order to solve the technical problem, the application adopts a technical scheme that: the utility model provides a sample analyzer, sample analyzer includes foretell mixing device, sampling device and controlling means, controlling means control mixing device moves in the vertical direction, and control sampling device moves in the horizontal direction, mixing device has first removal route in the vertical direction, sampling device has the second removal route in the horizontal direction, first removal route with the second removal route is spatial noninterference.
In order to solve the technical problem, the application adopts a technical scheme that: the utility model provides a sample analyzer, sample analyzer includes foretell mixing device, sampling device and controlling means, sampling device is used for transporting the test-tube rack of installing the test tube and advances a kind to mixing position, sampling position in proper order, mixing device is used for the test tube of grabbing on the sampling device to carry out mixing operation and put back on the sampling device the test-tube rack, the test-tube rack advance kind extremely sampling position is in order to supply the sample to carry out sample detection, controlling means judges whether the test tube after the sample need reinspection, if need reinspection, then controls sampling device will corresponding test tube on the test-tube rack transports back mixing position or sampling position carries out reinspection operation.
In order to solve the technical problem, the application adopts a technical scheme that: the utility model provides a sample analyzer, sample analyzer includes foretell mixing device, sampling device, relay subassembly and controlling means, sampling device is used for transporting the test-tube rack of installing the test tube and advances a kind to the mixing position, mixing device is used for snatching test tube on the sampling device carries out the mixing operation, relay subassembly be used for with the test tube after the mixing transport extremely sampling position in the sample analyzer, controlling means judges whether the test tube after the sampling needs retest, if needs retest, then control mixing position is returned to the corresponding test tube transport of sampling device on with the test-tube rack and is retested the operation.
The beneficial effect of this application is: be different from prior art, the mixing device that this application provided carries out the relative motion of opening and shutting through the first tongs of being connected with first driving medium and the second tongs of being connected with the second driving medium and realizes snatching the test tube, has avoided getting the test tube from a direction clamp, can prevent that the test tube from getting the in-process and being damaged when getting the test tube label, when the test tube label did not paste, the mode of opening and shutting the motion of snatching the test tube also can prevent to destroy the test tube label. Simultaneously, when getting the test tube from the injector clamp, the mode of the test tube that snatchs of the motion of opening and shutting does not have obvious effort to the test-tube rack, need not to set up spacing piece that blocks on test-tube rack both sides, has simplified the structural design of injector.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
fig. 1 is a schematic overall structure diagram of a blending device provided in an embodiment of the present application;
FIG. 2 is a schematic structural diagram of a first driving mechanism provided in an embodiment of the present application;
fig. 3 is a schematic overall structure diagram of a blending device provided in the second embodiment of the present application;
FIG. 4 is a schematic structural diagram of a first driving mechanism provided in a second embodiment of the present application;
fig. 5 is an overall structural schematic diagram of a blending device provided in the third embodiment of the present application;
FIG. 6 is a schematic structural diagram of a first driving mechanism provided in the third embodiment of the present application;
fig. 7 is a schematic structural diagram of a rotating mechanism provided in an embodiment of the present application;
FIG. 8 is a schematic structural diagram of a lifting mechanism provided in an embodiment of the present application;
FIG. 9 is a flow chart of a blending method provided in an embodiment of the present application;
fig. 10 is a schematic diagram of a transport path of a sample introduction assembly, a sampling assembly and a relay assembly of a sample analyzer according to an embodiment of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the present application.
Examples, rather than all examples. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are referred to in the embodiments of the present application, the directional indications are only used for explaining the relative position relationship between the components, the motion situation, and the like under a certain posture (as shown in the drawing), and if the certain posture is changed, the directional indications are changed accordingly.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present application, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present application.
Please refer to fig. 1, the present application provides a blending device, which includes a gripping unit 100, a rotating unit 200, and a lifting unit 300. The gripper assembly 100 comprises a first driving mechanism 110, the first driving mechanism 110 comprises a first transmission piece 111 and a second transmission piece 112 which can perform relative opening and closing movements, the gripper assembly 100 further comprises a first gripper 113 and a second gripper 114, wherein the first gripper 113 is connected with the first transmission piece 111, and the second gripper 114 is connected with the second transmission piece 112 and is arranged at a relative interval with the first gripper 113. The gripper assembly 100 is used to grip the test tube 10 from a test tube rack or tube holder.
The rotating mechanism 200 is connected with the gripper assembly 100 and used for driving the gripper assembly 100 to wholly shake so as to uniformly mix the samples. The lifting mechanism 300 is connected to the rotating mechanism 200 for driving the rotating mechanism 200 to integrally lift to other modules (e.g., a relay assembly).
Referring to fig. 2, in an embodiment, the first driving mechanism 110 includes a cylinder body 120 and a first slide rail 121, the first slide rail 121 is disposed on a surface of the cylinder body 120, the first transmission member 111 and the second transmission member 112 are two first slide blocks slidably disposed on the slide rail, and the first gripper 113 and the second gripper 114 are respectively connected to the two first slide blocks. Under the driving of the cylinder body 120, the two first sliding blocks correspondingly perform opening and closing motions to further drive the first gripper 113 and the second gripper 114 to perform opening and clamping actions to grip the test tube 10. In particular, the first grip 113 and the second grip 114 can be moved synchronously towards each other to grip the test tube 10 and synchronously away from each other to release the test tube 10. It is also possible for the first gripper 113 and the second gripper 114 to move out of phase towards each other to grip the test tube 10 and out of phase away from each other to release the test tube 10. It is also possible that the first grip 113 is stationary, the second grip 114 is moved towards the first grip 113 to grip the test tube 10, and the second grip 114 is moved away from the first grip 113 to release the test tube 10, where the movement of the first grip 113 and the second grip 114 is not particularly limited. The first gripper 113 and the second gripper 114 are opened and closed by angular rotation, so that the cylinder 120 can open and close the first gripper 113 and the second gripper 114 by a small stroke.
In this embodiment, the upper chamfer 1141 of the first gripper 113 and/or the second gripper 114 may be a slope, which allows the test tube 10 to easily slide down under gravity, preventing the test tube 10 from being hooked on the cap, which may result in failure to release the test tube 10. The lower chamfer 1142 of the first gripper 113 and/or the second gripper 114 has an auxiliary alignment function. First tongs 113 and/or second tongs 114 are equipped with presses along portion 1131, and when first tongs 113 and/or second tongs 114 snatched test tube 10, press along portion 1131 and be located test tube 10 directly over, can impress test tube 10 into the test tube rack with test tube 10 when putting back the test tube rack unexpected condition (the label on test tube 10 takes place to become flexible or not paste the compactness for test tube 10 and test tube rack accommodation hole interfere and the jamming phenomenon). The cylinder body 120 is further provided with an air pipe connector 122 and an air pipe bracket 123, and the air pipe bracket 123 is used for assisting in fixing an air pipe connected with the air pipe connector 122.
Referring to fig. 3-4, in one embodiment, the first driving mechanism 110 includes a first bracket 130, a plurality of first pulleys 131, a first synchronous belt 132 and a telescopic cylinder 133. The plurality of first pulleys 131 are mounted based on the first bracket 130. The first synchronous belt 132 includes a first belt segment 1321 and a second belt segment 1322 which are horizontally spaced apart, and a third belt segment 1323 which is vertically spaced apart, and the first transmission member 111 and the second transmission member 112 are respectively connected to the first belt segment 1321 and the second belt segment 1322. The telescopic cylinder 133 comprises a vertical cylinder 1331 connected with the first bracket 130 and a vertical cylinder rod 1332 connected with the third belt body segment 1323 through a connecting piece 134, when the vertical cylinder rod 1332 is telescopic relative to the vertical cylinder 1331, the first belt body segment 1321 and the second belt body segment 1322 are driven to move so as to drive the first transmission piece 111 and the second transmission piece 112 to perform opening and closing movement, so that the first gripper 113 and the second gripper 114 connected with the first transmission piece 111 and the second transmission piece 112 perform opening and closing movement, and the actions of loosening the test tube 10 and clamping the test tube 10 are realized.
Referring to fig. 5-6, in an embodiment, the first driving mechanism 110 includes a second bracket 140, two second pulleys 141, a second timing belt 142, and a screw motor 143. Wherein two second pulleys 141 are mounted based on the second bracket 140. The second timing belt 142 includes a first belt body segment 1421 and a second belt body segment 1422 arranged at a horizontal interval, and the first transmission member 111 and the second transmission member 112 are respectively connected to the first belt body segment 1421 and the second belt body segment 1422. The lead screw motor 143 is disposed on the second bracket 140, and is used for driving the first transmission member 111 and the second transmission member 112 to perform opening and closing movements. The first driving mechanism 110 further includes a lead screw nut base 144, and the lead screw nut base 144 is screw-engaged with the lead screw motor 143 and is connected to the first belt section 1421.
Specifically, when the screw motor 143 rotates, the screw nut seat 144 is driven to rotate, so that the first belt section 1421 moves to drive the second synchronous belt 142 to move along the two second belt wheels 141, the first transmission piece 111 and the second transmission piece 112 respectively move on the first belt section 1421 and the second belt section 1422 in an opening and closing manner, and then the first gripper 113 and the second gripper 114 respectively connected with the first transmission piece 111 and the second transmission piece 112 move in an opening and closing manner, thereby realizing the actions of loosening the test tube 10 and clamping the test tube 10.
The application discloses mixing device adopts machine to add a and the design of sheet metal component, and simple structure is compact, can high-frequency, safe and reliable nature normal operating. Simultaneously, the action of opening and shutting through first tongs 113 and second tongs 114 carries out the centre gripping of test tube 10 and loosens, can avoid coming the centre gripping test tube 10 with the unilateral power and cause the damage of the label on test tube 10 and the test tube 10, secondly, the mode of grabbing test tube 10 of the motion of opening and shutting of first tongs 113 and second tongs 114 need not obvious effort to the test-tube rack, need not to set up spacing piece that blocks on the test-tube rack both sides, has simplified the structural design of device.
Referring to fig. 7, further, the rotating mechanism 200 includes a mounting plate 210, a rotating motor 220 and a third timing belt 230. The rotary motor 220 is installed on the mounting plate 210, and drives the gripper assembly 100 to rotate and swing through the third synchronous belt 230.
In one embodiment, the rotation mechanism further includes a driven wheel 240, a driving wheel 250, a rotation shaft 260, and a connection block 270 (see fig. 2). The driving wheel 250 is disposed at an output end of the rotating electrical machine 220, the driven wheel 240 is mounted based on the mounting plate 210 and spaced from the driving wheel 230, the third synchronous belt 230 is sleeved on the driving wheel 250 and the driven wheel 240, the rotating shaft 260 and the driven wheel 240 rotate synchronously, and the connecting block 270 is disposed at one end of the rotating shaft 260 and used for being connected with the first driving mechanism 110.
The rotating mechanism 200 further includes an optical coupler 290 (see fig. 1) and a limiting baffle 280 (see fig. 1) which are disposed on the mounting plate 210, the first driving mechanism 110 is provided with a light blocking sheet 124 (see fig. 1) corresponding to the optical coupler 290, and when the rotating motor 220 drives the first driving mechanism 110 to swing between the vertical direction and the preset angle, the limiting baffle 280 and the light blocking sheet 124 form a reverse rotation mechanical limiting, or the limiting baffle 280 and the gripper assembly 100 form a reverse rotation mechanical limiting.
Specifically, after the first driving mechanism 110 clamps the test tube 10, the test tube 10 is still in the vertical position and is fed into the rotating mechanism 200 for the sample mixing operation. The driving wheel 250 and the driven wheel 240 are rotated when the rotating motor 220 rotates, the third synchronous belt 230 and the rotating shaft 260 are driven to rotate synchronously, and then the first driving mechanism 110 connected with one end of the rotating shaft 260 swings back and forth according to a certain range of angles, so that the test tube 10 clamped by the first gripper 113 and the second gripper 114 swings synchronously, and the sample mixing is realized. In the swing in-process, test tube 10 swing angle swings certain angle from initial position, then gets back to initial position, and wherein initial position is the position when test tube 10 vertical state promptly, and angular position is controlled by opto-coupler 290 and rotating electrical machines 220's the pulse count, and the swing direction is for deviating from elevating system 300's direction. In the present embodiment, the swing angle ranges from the initial position (vertical state) of the test tube 10 to 120 degrees away from the lifting mechanism 300, wherein the initial position is mechanically limited by the limiting barrier 280 and the light blocking sheet 124, and the test tube holder is prevented from swinging reversely when returning to the initial position.
The application discloses mixing device drives the test tube 10 on the first actuating mechanism 110 in relatively large swing back and forth through rotating electrical machines 220 drive pivot, can make the abundant mixing of sample of test tube 10.
Referring to fig. 8, further, the lifting mechanism 300 includes a housing 310, a lifting motor 320 and a fourth timing belt 330. The lifting motor 320 is installed on the basis of the housing 310, and the fourth synchronous belt 330 is driven to rotate by the lifting motor 320, so as to drive the gripper assembly 100 and the rotating mechanism 200 to perform lifting movement integrally.
In an embodiment, the lifting mechanism 300 further includes a second slider 340 and a second slide rail 350. The second slide rail 350 is disposed on the housing 310, the second slider 340 is disposed on the second slide rail 350, the mounting plate 210 is connected to the second slider 340, the fourth timing belt 330 is driven to rotate by the lifting motor 320, and the first driving mechanism 110 and the rotating mechanism 200 are connected to the second slider 340 through the mounting plate 210. The elevating mechanism 300 further includes an up-down position sensing positioner 360 provided on the housing 310 for positioning a lowering position of the first driving mechanism 110 and the rotating mechanism 200.
Specifically, after the mixing operation of the test tube 10 is completed, the test tube 10 is in a vertical position, and the test tube 10 is ready to be placed in a receiving opening of another module (e.g., a relay assembly). The lifting motor 320 starts to work, the first driving mechanism 110 and the rotating mechanism 200 connected to the second sliding block 340 are lowered to a certain position in the receiving port through the movement of the second sliding rail 350, the accurate position positioning is realized through the combination control of the up-down position sensing positioner 360 and the pulse step number of the lifting motor 320, at this time, the first gripper 113 and the second gripper 114 are opened, and the test tube 10 is separated from the first gripper 113 and the second gripper 114. The lifting motor 320 ascends to take away the first driving mechanism 110 and the rotating mechanism 200 which do not clamp the test tube 10, and at the moment, other modules take away the uniformly mixed test tube 10 for analysis. The lifting motor 320 waits for the test tube 10 sent after the other modules are analyzed, at the moment, the lifting motor 320 starts to work, the first driving mechanism 110 and the rotating mechanism 200 are driven to descend to the receiving port position, the upper position sensing positioner 360 and the lower position sensing positioner 360 are combined with the pulse step number of the lifting motor 320 to control the accurate position positioning, the first gripper 113 and the second gripper 114 of the first driving mechanism 110 clamp the test tube 10, the lifting motor 320 upwards takes the first driving mechanism 110 and the rotating mechanism 200 clamping the test tube 10, after the other modules are retreated, the lifting motor 320 downwards moves to place the test tube 10 on an empty test tube rack of a sample injector at the bottom, at the moment, the first gripper 113 and the second gripper 114 are loosened, and the test tube 10 is released. The elevator motor 320 may wait for a new unanalyzed test tube 10 from the injector and, upon receipt of the command, start a new loop analysis process.
The embodiment of the application also provides a blending method, which is executed based on the blending device, and the blending device further comprises a control component (not shown) in communication connection with the gripping component 100 and the rotating mechanism 200. Referring to fig. 9, the method includes:
step S10: the control assembly controls the gripper assembly 100 to grip the test tube 10.
The control assembly controls the first driving mechanism 110 of the gripper assembly 100, and in one embodiment, controls the time for the cylinder body 120 to ventilate the air tube connector 122, so that the first gripper 113 and the second gripper 114 perform opening and closing movements to grip or release the test tube 10. In one embodiment, the control assembly controls the time of the extension and compression movement of the telescopic cylinder 133, so that the first gripper 113 and the second gripper 114 perform the opening and closing movement to grip or release the test tube 10. In another embodiment, the control assembly controls the rotation direction of the lead screw motor 143, for example, when the lead screw motor 143 rotates in a forward direction, the first and second grippers 113 and 114 perform a closing motion to grip the test tube 10, and when the lead screw motor 143 rotates in a reverse direction, the first and second grippers 113 and 114 perform an opening motion to release the test tube 10. Step S20: the control component controls the rotating mechanism 200 to drive the gripper component 100 to swing back and forth within a preset angle range so as to perform the mixing action of the test tube 10.
The control assembly drives the gripper assembly 100 to swing back and forth within a preset angle range by controlling the rotation direction and the rotation time of the rotating motor 220 of the rotating mechanism 200 so as to uniformly mix the test tubes 10. In one embodiment, for example, when the control module controls the rotating motor 220 to rotate forward for 1 minute to swing the gripper assembly 100 to the maximum preset angle, and then the control module controls the rotating motor 220 to rotate backward for 1 minute to return the gripper assembly 100 to the original position, the control module controls the rotating motor 220 to perform the above-mentioned cyclic operation, so as to drive the gripper assembly 100 to swing back and forth within the preset angle range to mix the test tubes 10. Embodiments of the present application also provide a sample analyzer, which includes the blending apparatus, the relay assembly 30 (as shown in fig. 10) and the control assembly. The control assembly controls the gripper assembly 100 to grip the test tube 10, the control assembly controls the rotating mechanism 200 to drive the gripper assembly 100 to swing back and forth within a preset angle range so as to uniformly mix the test tube 10, and the control assembly controls the relay assembly 30 to send the uniformly mixed test tube 10 to a sampling position in the sample analyzer.
As shown in fig. 10, the sample analyzer further includes a sample introduction assembly 20 having a first transport path X and a sampling assembly 40 having a third transport path Z, and the relay assembly 30 has a second transport path Y forming an angle with the first transport path X and the third transport path Z. The sampling assembly 20, the sampling assembly 40 and the relay assembly 30 are not overlapped in spatial position, so that the serial operation and the parallel operation can be realized, and the running speed of the instrument can be improved by the parallel operation.
The embodiment of the application also provides a sample analyzer, and this sample analyzer includes foretell mixing device, sampling device and controlling means, and controlling means control mixing device moves in vertical direction to control sampling device and move in the horizontal direction, mixing device has first removal route in vertical direction, and sampling device has the second removal route in the horizontal direction, and first removal route does not interfere with the second removal route space. Because the blending device and the sampling device are not overlapped in spatial position and do not interfere with each other, serial operation and parallel operation can be realized, and the whole running speed of the instrument can be increased by realizing the parallel operation.
The embodiment of this application still provides a sample analyzer, this sample analyzer includes above-mentioned mixing device, sampling device and controlling means, sampling device is used for transporting the test-tube rack of installing the test tube and advances kind to the mixing position in proper order, the sampling position, mixing device is used for snatching the test tube on the sampling device and carries out the mixing operation and put back the test-tube rack on the sampling device, the test-tube rack advances kind to the sampling position and carries out sample detection in order to supply the sampling, controlling means judges whether the test tube after the sampling needs reinspection, if need reinspection, then control sampling device transports back mixing uniformity position or sampling position with the corresponding test tube on the test-tube rack and carries out the reinspection operation.
The embodiment of this application still provides a sample analyzer, this sample analyzer includes foretell mixing device, sampling device, relay subassembly and controlling means, sampling device is used for transporting the test-tube rack that installs the test tube and advances kind to the mixing position, mixing device is used for snatching the test tube on the sampling device and carries out the mixing operation, relay subassembly is used for transporting the test tube after the mixing to the sampling position in the sample analyzer, controlling means judges whether the test tube after the sampling needs retest, if need retest, then control sampling device transports the corresponding test tube on with the test-tube rack back to the mixing position and go on retest the operation.
In conclusion, what those skilled in the art understand is that, the blending device that this application provided, the centre gripping that opens and shuts through first tongs 113 and second tongs 114 is carried out test tube 10 with unclamping, can avoid coming the damage that the centre gripping test tube 10 caused the label on test tube 10 and the test tube 10 with the unilateral power, secondly, when getting test tube 10 from the injector clamp, the mode of the test tube 10 of snatching of the motion of opening and shutting does not have obvious effort to the test tube rack, need not to set up spacing piece that blocks on the test tube rack both sides, the structural design of injector has been simplified. The rotating shaft is driven by the rotating motor 220 to drive the test tube 10 on the first driving mechanism 110 to swing back and forth in a large range, so that the samples of the test tube 10 can be fully mixed. The test tube 10 on the first driving mechanism 110 is lifted by the synchronous belt mode of the lifting motor 320, so that the automation of sampling analysis of the uniformly mixed sample is realized. The whole blending device adopts the design of machining parts and sheet metal parts, has simple and compact structure, can normally run at high frequency, safely and reliably, and is simple and convenient to maintain.
The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure, which are directly or indirectly applied to other related technical fields, are included in the scope of the present disclosure.

Claims (18)

1. A blending device, which is characterized by comprising:
the gripper assembly comprises a first driving mechanism, a first gripper and a second gripper;
the first driving mechanism comprises a first transmission piece and a second transmission piece which can perform relative opening and closing movement; the first handle is connected with the first transmission piece;
the second gripper is connected with the second transmission piece and is arranged opposite to the first gripper at intervals;
and the rotating mechanism is used for driving the gripper assembly to perform uniform mixing action.
2. The blending apparatus of claim 1, wherein the first drive mechanism further comprises:
a cylinder body;
the first sliding rail is arranged on the cylinder body, the first transmission part and the second transmission part are arranged on the two first sliding blocks on the sliding rail in a sliding mode, the first gripper and the second gripper are connected with the two first sliding blocks respectively, and under the driving of the cylinder body, the two first sliding blocks correspondingly move in an opening and closing mode to drive the first gripper and the second gripper to move in an opening and closing mode to grip a test tube.
3. The blending device of claim 2, wherein the first gripper and/or the second gripper are provided with a pressing edge part, and the pressing edge part is positioned right above the test tube when the first gripper and/or the second gripper grip the test tube.
4. The blending device according to claim 2, wherein the cylinder body is further provided with an air pipe connector and an air pipe bracket, and the air pipe bracket is used for assisting in fixing an air pipe connected with the air pipe connector.
5. The blending apparatus of claim 1, wherein the first drive mechanism comprises:
a first bracket;
a plurality of first pulleys mounted based on the first bracket;
the first synchronous belt comprises a first belt body section and a second belt body section which are horizontally arranged at intervals, and the first transmission piece and the second transmission piece are respectively connected to the first belt body section and the second belt body section;
and the telescopic cylinder is arranged on the first support and used for driving the first transmission piece and the second transmission piece to move in an opening and closing manner.
6. The blending device according to claim 5, wherein the first synchronous belt further comprises a third belt body section which is vertically arranged, the telescopic cylinder comprises a vertical cylinder body connected with the first support and a vertical cylinder rod connected with the third belt body section through a connecting piece, and the vertical cylinder rod drives the first belt body section and the second belt body section to move when stretching relative to the vertical cylinder body so as to drive the first transmission member and the second transmission member to open and close.
7. The blending apparatus of claim 1, wherein the first drive mechanism comprises:
a second bracket;
two second pulleys mounted based on the second bracket;
the second synchronous belt comprises a first belt body section and a second belt body section which are horizontally arranged at intervals, and the first transmission piece and the second transmission piece are respectively connected to the first belt body section and the second belt body section;
and the screw rod motor is arranged on the second support and used for driving the first transmission piece and the second transmission piece to open and close.
8. The blending device of claim 7, wherein the first driving mechanism further comprises a lead screw nut seat, and the lead screw nut seat is in threaded fit with the lead screw motor and is connected with the first belt section.
9. The blending device of claim 1, wherein the rotating mechanism is connected with the gripper assembly and used for driving the gripper assembly to rotate and swing, and the rotating mechanism comprises:
mounting a plate;
a third synchronous belt;
a rotating motor mounted based on the mounting plate;
the rotating motor drives the gripper assembly to rotate and swing through a third synchronous belt.
10. The blending device according to claim 7, wherein the rotating mechanism comprises an optical coupler and a limiting baffle arranged on the mounting plate, the first driving mechanism is further provided with a light barrier corresponding to the optical coupler, the rotating motor is used for driving the first driving mechanism to swing between a vertical direction and a preset angle, and the limiting baffle and the light barrier form a reverse rotation mechanical limit, or the limiting baffle and the hand grip assembly form a reverse rotation mechanical limit.
11. The blending device of claim 9, further comprising a lifting mechanism connected with the rotating mechanism for driving the rotating mechanism and the gripper assembly to integrally lift, wherein the lifting mechanism comprises:
a housing;
a lift motor mounted based on the housing;
and the fourth synchronous belt is driven to rotate by the lifting motor, so that the rotating mechanism and the whole gripper assembly are driven to move up and down.
12. A blending method, wherein the blending method is performed based on the blending device of claims 1-11, the blending device further comprises a control assembly in communication with the gripper assembly and the rotating mechanism, and the method comprises:
the control assembly controls the gripper assembly to grip the test tube;
the control assembly controls the rotating mechanism to drive the gripper assembly to swing back and forth within a preset angle range so as to perform test tube mixing action.
13. A sample analyzer, comprising the mixing apparatus of any of claims 1-11, a relay assembly, a control assembly, communicatively coupled thereto;
the control assembly controls the gripper assembly to grip the test tube;
the control assembly controls the rotating mechanism to drive the gripper assembly to swing back and forth within a preset angle range so as to perform test tube mixing operation;
and the control component controls the relay component to send the uniformly mixed test tube to a sampling position in the sample analyzer.
14. The sample analyzer of claim 13 further comprising a sample introduction assembly having a first transport path, the relay assembly having a second transport path angled from the first transport path.
15. The sample analyzer of claim 13 including a sampling assembly having a third transport path, the relay assembly having a second transport path angled with respect to the third transport path.
16. A sample analyzer, comprising the mixing device, the sampling device and the control device according to any one of claims 1 to 11, wherein the control device controls the mixing device to move in a vertical direction and controls the sampling device to move in a horizontal direction, the mixing device has a first moving path in the vertical direction, the sampling device has a second moving path in the horizontal direction, and the first moving path and the second moving path do not spatially interfere with each other.
17. The utility model provides a sample analyzer, characterized in that, sample analyzer includes mixing device, sampling device and controlling means of any of claims 1-11, sampling device is used for transporting the test-tube rack of installing the test tube and advances kind to mixing position, sampling position in proper order, mixing device is used for snatching the test tube on the sampling device and carries out the mixing operation and put back on the sampling device the test-tube rack, the test-tube rack advance kind to sampling position is in order to sample and carry out sample detection, controlling means judges whether the test tube after the sampling needs reinspection, if need reinspection, then control sampling device will corresponding test tube on the test-tube rack is transported back mixing position or sampling position carries out the reinspection operation.
18. The utility model provides a sample analyzer, its characterized in that, sample analyzer includes mixing device, sampling device, relay subassembly and controlling means of any one of claims 1-11, sampling device is used for transporting the test-tube rack that installs the test tube and advances kind to mixing position, mixing device is used for snatching test tube on the sampling device carries out mixing operation, relay subassembly is used for transporting the test tube after the mixing to sampling position in the sample analyzer, controlling means judges whether the test tube after the sampling needs retest, if needs retest, then controls the sampling device transports the corresponding test tube on the test-tube rack back to mixing position and carries out the retest operation.
CN202011503080.4A 2020-12-17 2020-12-17 Blending device and sample analyzer Pending CN114646524A (en)

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PCT/CN2021/119384 WO2022127247A1 (en) 2020-12-17 2021-09-18 Mixing device, and sample analyzer

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Application Number Priority Date Filing Date Title
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