CN108478468A - A kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask and preparation method thereof - Google Patents
A kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask and preparation method thereof Download PDFInfo
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- CN108478468A CN108478468A CN201810256972.5A CN201810256972A CN108478468A CN 108478468 A CN108478468 A CN 108478468A CN 201810256972 A CN201810256972 A CN 201810256972A CN 108478468 A CN108478468 A CN 108478468A
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- bacteria cellulose
- woven fabric
- facial mask
- medical bacteria
- fabric compounded
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention discloses a kind of preparation methods of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask, non-woven fabrics face paper is dipped in the zymotic fluid of bacteria cellulose, the stationary culture in the case where being suitble to temperature, bacteria cellulose is grown into the fiber of non-woven fabrics face paper in fermentation process, interpenetrating networks staggeredly are formed therewith, to which the two is closely compound.The medical bacteria cellulose being prepared the present invention also provides the above method/non-woven fabric compounded hydrogel facial mask.Medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask of the present invention is easily spread, and water content is high, has efficient absorption/diffusion double action, can effectively adsorb facial treatment essence liquid.When in use, which can efficiently discharge skin care ingredient, and keep good wettability.
Description
Technical field
The present invention relates to facial mask field, more particularly to a kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask and
Preparation method.
Background technology
Facial mask is a kind of carrier of face beautifying health keeping product, is divided into powder reconciliation class and the face paper made of various fabric textures
(cloth) class.The basic function of facial mask is by expanding pore, promoting skin metabolism, complete deep layer cleaning and moisturizing, U.S.
It is white to wait maintenances effect.Face paper is played a role by adsorbing Essence, and the unlike material of face paper has the function of facial mask larger
Influence.Face paper relatively good at present is biological fiber class, and followed by silk mask paper, blended non-woven fabrics take second place.
Bacteria cellulose is a kind of cellulose aquagel made from microbial fermentation, has fine nanofiber 3D knots
Structure assigns the material various excellent performances, if water content is high, there is powerful absorption and diffusion double action, elastic good, power
Have excellent performance, and biological safety is high, and is used for efficient wet union wound dressing.Equally, bacteria cellulose is excellent
Carrier property becomes a kind of extraordinary advanced facial mask paper carrier of performance, belongs to biology cellulose class.But merely thin
Fungin hydrogel facial mask is due to soft texture, it is difficult to it sprawls, it is inconvenient when use.
Invention content
In order to overcome the disadvantages mentioned above and deficiency of the prior art, the purpose of the present invention is to provide a kind of medical bacterial fibers
Element/non-woven fabric compounded hydrogel facial mask, is easily spread, and water content is high, there is efficient absorption/diffusion double action, Ke Yiyou
Effect absorption facial treatment essence liquid, when use, can efficiently discharge skin care ingredient, and keep good wettability.
The purpose of the present invention is achieved through the following technical solutions：
A kind of preparation method of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask, includes the following steps：
(1) acetobacter xylinum fermentation is used to prepare medical bacteria cellulose；
(2) it is inoculated in acetobacter xylinum strain to seed culture fluid, 25-32 DEG C of temperature, 150-200 revs/min of mixing speed, training
Time 16-24 hour is supported, seed liquor is obtained；
(3) seed liquor for the 8-12% that volume is culture solution is accessed in culture solution, mixing is spare, obtains zymotic fluid；
(4) zymotic fluid is injected into the culture vessel equipped with non-woven fabrics face paper, is bandaged, 25-32 DEG C of stationary culture
2-5 days, bacteria cellulose was grown into the fiber of non-woven fabrics face paper in fermentation process, forms interpenetrating networks staggeredly therewith,
Thus the two is closely compound, obtain medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask；
(5) by medical bacteria cellulose/non-woven fabric compounded cultured products deionized water rinse, remaining culture is removed
Liquid, is dipped to colourless with deionized water, and the sodium hydroxide solution of 0.05-0.5M extracts 1-2 times, and deionized water is washed till neutrality.
The non-woven fabrics face paper is pure cotton non-woven fabrics, silk mask paper, jute face paper or at fiber facial mask cloth.
The synthetic fibers are acrylic acid, nylon, polyethylene, polypropylene, polyester or viscose rayon.
Step (4) culture vessel equipped with non-woven fabrics face paper is the incubator of the presence or absence of sterilized woven fabric face paper
Ware, specific disinfecting process are：
Non-woven fabrics face paper is placed in culture vessel, is bandaged, it is high in the high temperature of 115-121 DEG C, 0.07-0.101MPa
Press strip part sterilizing 20-30min, is dried for standby in 30-80 DEG C.
A kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask, including medical bacteria cellulose aquagel layer and
The fiber of two layers of nonwoven layer, bacteria cellulose aquagel layer is grown into inside non-woven fabrics, forms interpenetrating networks staggeredly.
The thickness of the bacteria cellulose aquagel layer is 0.2-5mm.
Ranging from 50-200 μm of the fibre gap of the nonwoven layer.
The thickness of the nonwoven layer is 0.1-1.5mm.
Compared with prior art, the present invention has the following advantages and beneficial effect：
(1) medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask of the invention, can make full use of bacteria cellulose
Quick adsorption and diffusion double action, adsorb Essence, when use can diffuse to rapidly skin surface.
(2) medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask of the invention, bacteria cellulose aquagel film elasticity
Good, stickiness is good, and facial mask completely docile can improve facial mask in effective contact area of skin, promote Essence in face
Useful effect.
(3) the medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask invented, nonwoven fabric base effectively increase bacterium fibre
The spreading property of the plain film of dimension, ease of use greatly improve.
Description of the drawings
Fig. 1 is the scanning electricity of the medical bacteria cellulose/pure cotton non-woven fabrics composite hydrogel facial mask of the embodiment of the present invention 1
Mirror figure.
Fig. 2 is the scanning of the medical bacteria cellulose/polypropylene non-woven fabric composite hydrogel facial mask of the embodiment of the present invention 2
Electron microscope.
Specific implementation mode
With reference to embodiment, the present invention is described in further detail, embodiments of the present invention are not limited thereto.
Embodiment 1
The preparation method of the medical bacteria cellulose of the present embodiment/pure cotton non-woven fabrics composite hydrogel facial mask, including it is following
Step：
(1) the disinfection preparation of culture vessel
Pure cotton non-woven fabrics face paper is placed in discoid culture vessel, is bandaged, autoclave sterilization (115 DEG C,
30min), low temperature drying is spare (30 DEG C, 24 hours)；
(2) prepared by seed liquor
It is inoculated in acetobacter xylinum strain to seed culture fluid, 25 DEG C of temperature, 150 revs/min of mixing speed, incubation time 24 is small
When；
(3) prepared by zymotic fluid
By seed liquor according in 10% ratio access culture solution, mixing is spare.
(4) bacteria cellulose in-situ fermentation
The zymotic fluid that 200ml is injected in culture vessel, bandages, 25 DEG C of stationary cultures 4 days；
(5) purifying of medical bacteria cellulose/pure cotton non-woven fabrics composite hydrogel facial mask
By medical bacteria cellulose/pure cotton non-woven fabrics compound criteria product deionized water rinse, remaining culture is removed
Liquid, is dipped to colourless with deionized water, and the sodium hydroxide solution of 0.1M extracts 1 time, and deionized water is washed till neutrality.
Medical bacteria cellulose/pure cotton non-woven fabrics composite hydrogel facial mask, wherein bacteria cellulose aquagel thickness is made
2.0mm is spent, microstructure (Fig. 1) display inside scanning electron microscopic observation composite facial mask, cotton fiber (Fig. 1 arrow A marks) quilt
Bacteria cellulose nanofiber (Fig. 1 arrow B marks) covers, such as Fig. 1.
Be made medical bacteria cellulose/pure cotton non-woven fabrics composite hydrogel facial mask Essence absorb release, fitting rate and
Spreading property description is shown in Table 1.
Embodiment 2
The preparation method of the medical bacteria cellulose of the present embodiment/polypropylene non-woven fabric composite hydrogel facial mask, including with
Lower step：
(1) the disinfection preparation of culture vessel
Polypropylene non-woven fabric face paper is placed in discoid culture vessel, is bandaged, autoclave sterilization (121 DEG C,
0.101MPa, 20min), low temperature drying is spare (80 DEG C, 12 hours)；
(2) prepared by seed liquor
It is inoculated in acetobacter xylinum strain to seed culture fluid, 30 DEG C of temperature, 180 revs/min of mixing speed, incubation time 16-
24 hours；
(3) prepared by zymotic fluid
By seed liquor according in 10% ratio access culture solution, mixing is spare.
(4) bacteria cellulose in-situ fermentation
The zymotic fluid that 300ml is injected in culture vessel, bandages, 30 DEG C of stationary cultures 4 days；
(5) purifying of medical bacteria cellulose/polypropylene non-woven fabric composite hydrogel facial mask
By medical bacteria cellulose/polypropylene non-woven fabric compound criteria product deionized water rinse, remaining training is removed
Nutrient solution, is dipped to colourless with deionized water, and the sodium hydroxide solution of 0.5M extracts 2 times, and deionized water is washed till neutrality.
Medical bacteria cellulose obtained/polypropylene non-woven fabric composite hydrogel facial mask, wherein bacteria cellulose aquagel
Layer thickness 3.5mm.Microstructure (Fig. 2) display inside scanning electron microscopic observation composite facial mask, polypropylene fibre (Fig. 2 arrows A marks
At note) and bacteria cellulose Nanofiber Network (Fig. 2 arrow B marks) formation inierpeneirating network structure, illustrate that the two is compound tight
It is close.
The Essence that medical bacteria cellulose/polypropylene composite materials hydrogel facial mask is made absorbs release, fitting rate and sprawls
Performance description is shown in Table 1.
Medical bacteria cellulose/pure cotton non-woven fabrics composite hydrogel (BC/ pure cottons) that embodiment 1 is prepared is implemented
Medical bacteria cellulose/polypropylene non-woven fabric composite hydrogel (BC/ polypropylene) that example 2 is prepared, pure cotton non-woven fabrics, poly- third
Alkene non-woven fabrics, medical pure bacteria cellulose (pure BC) carry out Essence absorptivity and rate of release detection, the evaluation of fitting rate respectively
It is evaluated with spreading property.
1) Essence absorptivity detects
It is injected separately into collagen Essence 30ml in beaker, weighs quality and is denoted as M1, by sample to be tested (10cm ×
It 10cm) impregnates, takes out sample to be tested after 5min, the quality for detecting beaker and remaining Essence is denoted as M2.It is calculated according to formula 1
Essence absorptivity VIt absorbs, each sample setting 3 is parallel, is averaged.
VIt absorbs=(M1-M2)/100(g/cm2) (formula 1)
2) Essence rate of release detection method
The sample (10cm × 10cm) for having impregnated Essence is weighed to quality respectively and is denoted as M3, it is affixed on testing staff's arm,
Sample to be tested is removed after 15min, quality is weighed and is denoted as M4.Essence absorption rate V is calculated according to formula 2Release, each sample
Setting 3 is parallel, is averaged.
VRelease=(M3-M4)/15×100(g/min·cm2) (formula 2)
3) while testing staff being asked to evaluate the fitting rate and spreadability of all kinds of film samples, test result is shown in Table 1.
The performance of 1 all kinds of mask sheets of table
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by the embodiment
Limitation, it is other it is any without departing from the spirit and principles of the present invention made by changes, modifications, substitutions, combinations, simplifications,
Equivalent substitute mode is should be, is included within the scope of the present invention.
Claims (8)
1. a kind of preparation method of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask, which is characterized in that including following step
Suddenly：
(1) acetobacter xylinum fermentation is used to prepare medical bacteria cellulose；
(2) it is inoculated in acetobacter xylinum strain to seed culture fluid, 25-32 DEG C of temperature, 150-200 revs/min of mixing speed, when culture
Between 16-24 hours, obtain seed liquor；
(3) seed liquor for the 8-12% that volume is culture solution is accessed in culture solution, mixing is spare, obtains zymotic fluid；
(4) zymotic fluid is injected into the culture vessel equipped with non-woven fabrics face paper, is bandaged, 25-32 DEG C of stationary culture 2-5
It, bacteria cellulose is grown into the fiber of non-woven fabrics face paper in fermentation process, forms interpenetrating networks staggeredly therewith, to
The two is closely compound, obtain medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask；
(5) by medical bacteria cellulose/non-woven fabric compounded cultured products deionized water rinse, remaining culture solution is removed, is used
Deionized water is dipped to colourless, and the sodium hydroxide solution of 0.05-0.5M extracts 1-2 times, and deionized water is washed till neutrality.
2. the preparation method of medical bacteria cellulose according to claim 1/non-woven fabric compounded hydrogel facial mask, feature
It is, the non-woven fabrics face paper is pure cotton non-woven fabrics, silk mask paper, jute face paper or at fiber facial mask cloth.
3. the preparation method of medical bacteria cellulose according to claim 2/non-woven fabric compounded hydrogel facial mask, feature
It is, the synthetic fibers are acrylic acid, nylon, polyethylene, polypropylene, polyester or viscose rayon.
4. the preparation method of medical bacteria cellulose according to claim 1/non-woven fabric compounded hydrogel facial mask, feature
It is, step (4) culture vessel equipped with non-woven fabrics face paper is the culture vessel of the presence or absence of sterilized woven fabric face paper,
Specifically disinfecting process is：
Non-woven fabrics face paper is placed in culture vessel, is bandaged, in 115-121 DEG C, the high temperature and pressure item of 0.07-0.101MPa
Part sterilizing 20-30min, is dried for standby in 30-80 DEG C.
5. a kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask, which is characterized in that including medical bacteria cellulose water
Two layers of gel layer and nonwoven layer, the fiber of bacteria cellulose aquagel layer is grown into inside non-woven fabrics, forms interpenetrating net staggeredly
Network.
6. medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask according to claim 5, which is characterized in that described thin
The thickness of fungin hydrogel layer is 0.2-5mm.
7. medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask according to claim 5, which is characterized in that the nothing
Ranging from 50-200 μm of the fibre gap of woven fabric layer.
8. medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask according to claim 5, which is characterized in that the nothing
The thickness of woven fabric layer is 0.1-1.5mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810256972.5A CN108478468B (en) | 2018-03-27 | 2018-03-27 | Medical bacterial cellulose/non-woven fabric composite hydrogel mask and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810256972.5A CN108478468B (en) | 2018-03-27 | 2018-03-27 | Medical bacterial cellulose/non-woven fabric composite hydrogel mask and preparation method thereof |
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| CN108478468A true CN108478468A (en) | 2018-09-04 |
| CN108478468B CN108478468B (en) | 2020-11-24 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109736097A (en) * | 2019-01-28 | 2019-05-10 | 陕西科技大学 | A kind of bacteria cellulose composite ultrafine fiber synthetic leather and preparation method thereof |
| CN110158311A (en) * | 2019-05-31 | 2019-08-23 | 盐城工业职业技术学院 | A kind of boron nitride nanosheet is modified to carbonize bacteria cellulose/carbon fibre fabric based composites and preparation method thereof |
| CN111437221A (en) * | 2019-01-16 | 2020-07-24 | 北京大学 | Mite-removing free radical hydrogel mask |
| CN112323494A (en) * | 2020-11-06 | 2021-02-05 | 南京林业大学 | Efficient preparation method of bacterial cellulose/non-woven fiber composite mask base cloth |
| CN112513356A (en) * | 2018-09-27 | 2021-03-16 | 株式会社Lg化学 | Biological cellulose tablet and preparation method thereof |
| CN114028311A (en) * | 2021-12-09 | 2022-02-11 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method of hydrogel mask, product and application thereof |
| CN114191415A (en) * | 2021-12-27 | 2022-03-18 | 福建长源纺织有限公司 | Eye protection film and preparation method thereof |
-
2018
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112513356A (en) * | 2018-09-27 | 2021-03-16 | 株式会社Lg化学 | Biological cellulose tablet and preparation method thereof |
| EP3812494A4 (en) * | 2018-09-27 | 2021-08-18 | Lg Chem, Ltd. | Bio-cellulose sheet and preparation method thereof |
| CN111437221A (en) * | 2019-01-16 | 2020-07-24 | 北京大学 | Mite-removing free radical hydrogel mask |
| CN109736097A (en) * | 2019-01-28 | 2019-05-10 | 陕西科技大学 | A kind of bacteria cellulose composite ultrafine fiber synthetic leather and preparation method thereof |
| CN110158311A (en) * | 2019-05-31 | 2019-08-23 | 盐城工业职业技术学院 | A kind of boron nitride nanosheet is modified to carbonize bacteria cellulose/carbon fibre fabric based composites and preparation method thereof |
| CN112323494A (en) * | 2020-11-06 | 2021-02-05 | 南京林业大学 | Efficient preparation method of bacterial cellulose/non-woven fiber composite mask base cloth |
| CN112323494B (en) * | 2020-11-06 | 2022-06-03 | 南京林业大学 | Efficient preparation method of bacterial cellulose/non-woven fiber composite mask base cloth |
| CN114028311A (en) * | 2021-12-09 | 2022-02-11 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method of hydrogel mask, product and application thereof |
| CN114191415A (en) * | 2021-12-27 | 2022-03-18 | 福建长源纺织有限公司 | Eye protection film and preparation method thereof |
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