CN111437221A - Mite-removing free radical hydrogel mask - Google Patents
Mite-removing free radical hydrogel mask Download PDFInfo
- Publication number
- CN111437221A CN111437221A CN201910040278.4A CN201910040278A CN111437221A CN 111437221 A CN111437221 A CN 111437221A CN 201910040278 A CN201910040278 A CN 201910040278A CN 111437221 A CN111437221 A CN 111437221A
- Authority
- CN
- China
- Prior art keywords
- free radical
- hydrogel
- gold
- temperature plasma
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention uses a self-made atmospheric pressure low-temperature plasma generator, uses an alternating current or pulse power supply to excite deionized water to obtain a plasma free radical activating solution, and prepares the mite-removing free radical hydrogel mask by taking the plasma free radical activating solution as a main component. Compared with the traditional facial mask on the market at present, the free radical hydrogel facial mask prepared by the method has double functions, on one hand, a back lining layer is a nitrocellulose base membrane containing gold nanoparticles, so that facial mites can be effectively identified, and meanwhile, the hydrogel layer is supported, wherein the gold nanoparticles are obtained by treating a mixed solution of saturated gold chloride and trisodium citrate by using a self-made plasma generator; on the other hand, the surface layer is a free radical hydrogel layer, so that recognized mites can be effectively removed, and the moisture-keeping effect is achieved. The mite-removing free radical hydrogel mask prepared by the method has an obvious effect, is safe, has no preservative, and has potential commercial value.
Description
■ field of the invention
The invention relates to a method for preparing a mite-removing free radical hydrogel mask and a mask product obtained by the method. The invention can be used in the field of daily chemical beauty products.
■ background of the invention
Beauty is always the existence of people who pursue, and the mask is the most common carrier for beautifying people. Today, more and more people are applying facial masks for skin care and facial repair. The facial mask becomes an indispensable daily care product in modern skin care products. The existing facial masks made of powder blend, kaolin, non-woven fabrics, silk facial masks, tencel facial masks, biological fiber facial masks and non-woven fabric facial masks in the market are widely used, but most of the facial masks have limited effects, usually make up for cleaning work of makeup removal and insufficient face washing, and are matched with other essential components to realize the maintenance functions of moisturizing, whitening, resisting aging, balancing grease and the like.
It is well known that mites are closely related to human health, such as spider mites, chiggers, scabies, demodex, dust mites and pyemotes, which can bite people to suck blood and invade skin, causing "rosacea" or demodex, anaphylaxis, urinary tract mite, pulmonary mite, intestinal mite and scabies, seriously harming human health.
More importantly, no relevant acarid-removing report exists at present. In conclusion, the development of a mask capable of safely and effectively removing mites is very expected.
In recent years, researchers have found that low-temperature plasma can generate a plurality of active oxygen radicals when interacting with aqueous solutionFrom radicals and reactive nitrogen radicals, e.g. superoxide anion radicals (. O)2 -) Hydroxyl radical (. OH), and nitric oxide radical (. NO), etc. The free radicals enable the plasma activated aqueous solution to have higher oxidation-reduction potential and show stronger oxidation capacity. Due to the excellent performance and the safety and no addition of the plasma free radical activated water solution, the plasma free radical activated water solution can be used for microbial sterilization, such as inactivation of escherichia coli, inactivation of staphylococcus aureus and the like; the effectiveness and safety of the fields of fruit preservation, fruit and vegetable pesticide residue removal and the like are verified.
Interestingly, hydrogel, as a water-rich carrier, has excellent water absorption and retention functions, and is widely used as a wound healing dressing, a drug delivery carrier, an antibacterial gel pad, and the like. Therefore, the hydrogel is used as a carrier of the plasma activated water, and the excellent biochemical function of the plasma activated water is utilized, so that the safe and efficient acarid-removing hydrogel mask is invented. The details are as follows.
■ summary of the invention
The invention uses a self-made atmospheric pressure low-temperature plasma generator, uses an alternating current or pulse power supply to excite deionized water to obtain a plasma free radical active aqueous solution, and prepares the free radical hydrogel mask for removing acarids by taking the plasma free radical active aqueous solution as a main active ingredient.
Preferably, compared with the traditional mask on the market at present, the free radical hydrogel mask prepared by the method has double functions, on one hand, the back lining layer is a nitrocellulose bottom membrane containing gold nanoparticles, the mites on the surface layer of the face can be effectively identified through color reaction, and meanwhile, the free radical hydrogel layer can be supported, wherein the gold nanoparticles are obtained by using low-temperature plasma excited by a plasma generator under the atmospheric pressure condition to act on a mixed aqueous solution of saturated gold chloride and trisodium citrate. On the other hand, the surface layer is a free radical hydrogel layer, and the raw materials of the free radical hydrogel layer comprise 98-99.5% of free radical activated water and 0.5-2.0% of natural cross-linking agent according to mass percentage. The free radical hydrogel layer can effectively remove mites identified by the nitrocellulose membrane and has a moisturizing effect.
Preferably, the nitrocellulose membrane is characterized in that: the antibody comprises a Der-P2 monoclonal antibody marked by gold particles, wherein the particle size of the gold nanoparticles is 20-60 nm, and the coverage rate is 3-6%; the gold nanoparticles are obtained by treating a mixed aqueous solution of saturated gold chloride and trisodium citrate by using an atmospheric pressure low-temperature plasma generator; the thickness of the membrane is 18mm-25mm, and the aperture of the membrane is 5um-10 um;
preferably, the free radical activated water is characterized by containing reactive oxygen radicals ROS and reactive nitrogen radicals RNS, and the total content of the reactive free radicals is 0.5 mu mol/L-10 nmol/L.
Preferably, the radical-activated water is characterized in that: exciting atmospheric pressure low temperature plasma in deionized water by using an alternating current or pulse power supply, wherein the treatment time is 1-10 min; wherein the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of the power supply is 3-12kV, and the frequency is 10-50 kHz.
The mite-removing free radical hydrogel mask prepared by the method has an obvious effect, is safe, has no preservative, and has a potential commercial value in the field of daily cosmetics.
■ brief description of the drawings
Fig. 1 is a schematic view of a mask. The lower layer is a nitrocellulose basement membrane, and the upper layer is a free radical hydrogel layer;
■ detailed description
The present invention is further illustrated by the following examples, but is not limited thereto.
Example 1
The preparation method of the nitrocellulose membrane comprises the following steps:
according to the volume percentage, 0.05-0.15 percent of gold chloride, 0.10-0.20 percent of trisodium citrate and 99.65-99.85 percent of deionized water are taken, and a plasma generator is used for exciting low-temperature plasma under the atmospheric pressure condition to obtain nano-gold particles; then, uniformly mixing 90 percent (mass percent) of prepared gold nanoparticles, 10 percent (mass percent) of 0.1M phosphate buffer solution with pH value of 7.4 and the Der-P2 monoclonal antibody to prepare a mixed solution of the Der-P2 monoclonal antibody marked by the gold particles; uniformly coating the gold particle-labeled Der-P2 monoclonal antibody mixed solution on a nitrocellulose membrane or soaking the nitrocellulose membrane in the gold particle-labeled Der-P2 monoclonal antibody mixed solution, uniformly dispersing gold particles on a bottom membrane by using a capillary principle, taking out, drying or airing overnight to obtain the nitrocellulose membrane.
The gold particle-labeled Der-P2 monoclonal antibody is contained, the thickness of the nitrocellulose membrane is 18mm-25mm, and the membrane aperture is 5um-10 um; the particle size of the gold nanoparticles is 20-60 nm, and the coverage rate is 3-6%; the gold nanoparticles are obtained by using low-temperature plasma excited by a plasma generator under the atmospheric pressure condition to act on a mixed aqueous solution of saturated gold chloride and trisodium citrate;
the nitrocellulose membrane in the embodiment can be prepared into a required shape and size according to actual requirements, and can be used for identifying facial mites.
Example 2
The preparation method of the free radical hydrogel mask comprises the following steps:
and (3) extending the low-temperature plasma generator and the positive and negative electrodes into deionized water, exciting the low-temperature plasma under atmospheric pressure, and stirring for 1-10min while processing to obtain a plasma activated water solution rich in ROS and RNS. According to volume percentage, adding 0.5-2.0% of natural cross-linking agent into 98-99.5% of plasma activated water solution, wherein the step needs to be operated with the assistance of a stirrer, and obtaining solution A after uniform stirring; and cooling and forming the solution A at the temperature of 0-4 ℃ for 3min to obtain the free radical hydrogel mask.
The natural cross-linking agent is composed of at least two of 0.2-1.5% of soybean protein glue, 0.2-2.0% of agar, 0.5-2.0% of alginate, 0.2-1.0% of pectin, 1-2% of xanthan gum and 0.2-10% of gelatin;
wherein, the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of an alternating current or pulse power supply is 3-12kV, and the frequency is 10-50 kHz;
the free radical hydrogel facial mask in the embodiment can be prepared into a required shape according to actual requirements, and can be used as a daily moisturizing facial mask.
Example 3
Preparation of a free radical hydrogel wound healing dressing comprising the steps of:
and (3) extending the low-temperature plasma generator and the positive and negative electrodes into deionized water, exciting the low-temperature plasma under atmospheric pressure, and stirring for 1-10min while processing to obtain a plasma activated water solution rich in ROS and RNS. According to volume percentage, 0.5 to 2.0 weight percent of natural cross-linking agent and 15 to 25 weight percent of quaternized chitosan-g-polyaniline are added into 73 to 84.5 weight percent of plasma activation aqueous solution; the step needs to be operated under the assistance of a stirrer, and a mixed solution is obtained after uniform stirring; and cooling and forming the mixed solution at the temperature of 0-4 ℃ for 30min to obtain the free radical hydrogel wound healing dressing.
Wherein, the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of an alternating current or pulse power supply is 3-12kV, and the frequency is 10-50 kHz;
the natural cross-linking agent is composed of at least two of 0.2-1.5% of soybean protein glue, 0.2-2.0% of agar, 0.5-2.0% of alginate, 0.2-1.0% of pectin, 1-2% of xanthan gum and 0.2-10% of gelatin;
the free radical hydrogel wound healing dressing in this example can be made to the desired size and shape according to actual wound requirements and can be used as a healing dressing gel.
Example 4
The preparation of the free radical antibacterial hydrogel comprises the following steps:
and (3) extending the low-temperature plasma generator and the positive and negative electrodes into deionized water, exciting the low-temperature plasma under atmospheric pressure, and stirring for 1-10min while processing to obtain a plasma activated water solution rich in ROS and RNS. According to volume percentage, 0.5 to 2.0 weight percent of natural cross-linking agent and 10 to 15 weight percent of polyacrylic acid are added into 83 to 89.5 weight percent of plasma activated water solution; the step needs to be operated under the assistance of a stirrer, and a mixed solution is obtained after uniform stirring; and cooling and forming the mixed solution at the temperature of 0-4 ℃ for 30min to obtain the free radical hydrogel wound healing dressing.
Wherein, the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of an alternating current or pulse power supply is 3-12kV, and the frequency is 10-50 kHz;
the natural cross-linking agent is composed of at least two of 0.2-1.5% of soybean protein glue, 0.2-2.0% of agar, 0.5-2.0% of alginate, 0.2-1.0% of pectin, 1-2% of xanthan gum and 0.2-10% of gelatin;
the free radical antibacterial hydrogel in the embodiment can be prepared into a required size and shape according to actual requirements, and can be used as an antibacterial gel.
Example 5
Preparation of a drug delivery free radical hydrogel comprising the steps of:
and (3) extending the low-temperature plasma generator and the positive and negative electrodes into deionized water, exciting the low-temperature plasma under atmospheric pressure, and stirring for 1-10min while processing to obtain a plasma activated water solution rich in ROS and RNS. According to volume percentage, 0.5-2.0 wt% of natural cross-linking agent and 8-18 wt% of cysteine modified adriamycin, paclitaxel or docetaxel and other anti-cancer drugs are added into 80-91.5 wt% of plasma activated water solution; the step needs to be operated under the assistance of a stirrer, and a mixed solution is obtained after uniform stirring; and cooling the mixed solution at 0-4 ℃ for 30min to obtain the drug delivery free radical hydrogel.
Wherein, the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of an alternating current or pulse power supply is 3-12kV, and the frequency is 10-50 kHz;
the natural cross-linking agent is composed of at least two of 0.2-1.5% of soybean protein glue, 0.2-2.0% of agar, 0.5-2.0% of alginate, 0.2-1.0% of pectin, 1-2% of xanthan gum and 0.2-10% of gelatin;
the drug delivery radical hydrogel in the present example can be prepared into a desired size and shape according to actual needs, and can be used as a drug delivery hydrogel.
Claims (8)
1. The free radical hydrogel mask for removing mites is characterized in that: the facial mask consists of two layers, wherein the back lining layer is a nitrocellulose basement membrane, and the surface layer is a free radical hydrogel layer and does not contain a preservative; wherein the free radical hydrogel layer is composed of free radical activated water and a natural cross-linking agent.
2. The nitrocellulose membrane of claim 1, wherein: the antibody comprises a Der-P2 monoclonal antibody marked by gold particles, wherein the particle size of the gold nanoparticles is 20-60 nm, and the coverage rate is 3-6%; the gold nanoparticles are obtained by processing a mixed aqueous solution of saturated gold chloride and trisodium citrate by using an atmospheric pressure low-temperature plasma; the thickness of the membrane is 18mm-25mm, and the aperture of the membrane is 5um-10 um.
3. The free radical hydrogel layer of claim 1, wherein: measured by mass percent, 98 to 99.5 percent of free radical activated water and 0.5 to 2 percent of natural cross-linking agent.
4. The radical-activated water according to claim 3, which contains reactive oxygen radicals ROS and reactive nitrogen radicals RNS, and the total content of the reactive radicals is 0.5. mu. mol/L-10 nmol/L.
5. The radical-activated water according to claim 3, characterized in that: exciting atmospheric pressure low temperature plasma in deionized water by using an alternating current or pulse power supply, wherein the treatment time is 1-10 min; wherein the working gas of the atmospheric pressure low-temperature plasma is selected from one or more of air, nitrogen, oxygen, helium, argon and neon, the working voltage of the power supply is 3-12kV, and the frequency is 10-50 kHz.
6. The natural crosslinking agent of claim 3, wherein: is prepared from at least two of soybean protein gel 0.2-1.5%, agar 0.2-2.0%, alginate 0.5-2.0%, pectin 0.2-1.0%, xanthan gum 1-2% and gelatin 0.2-10%.
7. The preparation method of the mite-removing free radical hydrogel mask as claimed in claims 1 to 6, which is characterized in that: the method comprises the following steps:
1) taking 0.1 percent (volume percentage) of gold chloride, 0.15 percent of trisodium citrate and 99.75 percent of deionized water, and treating the gold chloride, the trisodium citrate and the deionized water by using low-temperature plasma excited under the atmospheric pressure condition to obtain nano-gold particles;
2) mixing and uniformly stirring 90% of the gold nanoparticles prepared in the step 1, 0.1M phosphate buffer solution pH7.4 (10%) and the Der-P2 monoclonal antibody according to mass percentage to obtain a gold particle-labeled Der-P2 monoclonal antibody;
3) uniformly coating the gold particle-labeled Der-P2 monoclonal antibody on a nitrocellulose membrane, or soaking the nitrocellulose membrane in the gold particle-labeled Der-P2 monoclonal antibody, uniformly dispersing gold particles on a bottom membrane by using a capillary principle, and then taking out and drying or airing overnight;
4) extending a low-temperature plasma generator and a positive electrode and a negative electrode into deionized water, exciting the low-temperature plasma under atmospheric pressure, and treating for 1-10min to obtain free matrix activated water containing active oxygen free radicals and active nitrogen free radicals;
5) adding 0.5-2.0% of natural cross-linking agent into free radical activated water, and then uniformly stirring by using a stirrer to obtain a solution A;
6) and uniformly coating the solution A on the surface of the dried or aired nitrocellulose base membrane, and cooling and forming at 0-4 ℃.
8. The use method of the mite-removing free radical hydrogel mask as claimed in claims 1-7, wherein the nitrocellulose membrane is peeled off after being applied to the face for 15min-20 min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910040278.4A CN111437221A (en) | 2019-01-16 | 2019-01-16 | Mite-removing free radical hydrogel mask |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910040278.4A CN111437221A (en) | 2019-01-16 | 2019-01-16 | Mite-removing free radical hydrogel mask |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111437221A true CN111437221A (en) | 2020-07-24 |
Family
ID=71626636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910040278.4A Pending CN111437221A (en) | 2019-01-16 | 2019-01-16 | Mite-removing free radical hydrogel mask |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111437221A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022110183A1 (en) * | 2020-11-30 | 2022-06-02 | L'oreal | Mask composition and process |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306164A (en) * | 2014-10-21 | 2015-01-28 | 长春吉原生物科技有限公司 | Hydrogel mask for laser treatment and preparation method thereof |
| CN104997663A (en) * | 2015-06-25 | 2015-10-28 | 徐伟明 | Negative oxygen ion-catalyzed traditional Chinese medicine whitening mask and preparation method thereof |
| CN105125420A (en) * | 2015-10-09 | 2015-12-09 | 固安博健生物技术有限公司 | Drug gel system for relieving conventional skin problems and preparation method thereof |
| CN105476867A (en) * | 2016-01-21 | 2016-04-13 | 阮仕星 | Human-beautifying multi-layer gel facial mask |
| CN205729815U (en) * | 2016-01-21 | 2016-11-30 | 广州欧诺洁个人护理用品有限公司 | Human body beauty treatment multilayer gel facial film |
| CN206454028U (en) * | 2016-06-01 | 2017-09-01 | 南京天朗制药有限公司 | Body temperature is moulded into type skin nursing film certainly |
| CN107898714A (en) * | 2017-12-28 | 2018-04-13 | 湖南龙丰茯苓科技开发有限公司 | A kind of humidity-preserving type tuckahoe facial mask |
| CN108478468A (en) * | 2018-03-27 | 2018-09-04 | 华南理工大学 | A kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask and preparation method thereof |
-
2019
- 2019-01-16 CN CN201910040278.4A patent/CN111437221A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306164A (en) * | 2014-10-21 | 2015-01-28 | 长春吉原生物科技有限公司 | Hydrogel mask for laser treatment and preparation method thereof |
| CN104997663A (en) * | 2015-06-25 | 2015-10-28 | 徐伟明 | Negative oxygen ion-catalyzed traditional Chinese medicine whitening mask and preparation method thereof |
| CN105125420A (en) * | 2015-10-09 | 2015-12-09 | 固安博健生物技术有限公司 | Drug gel system for relieving conventional skin problems and preparation method thereof |
| CN105476867A (en) * | 2016-01-21 | 2016-04-13 | 阮仕星 | Human-beautifying multi-layer gel facial mask |
| CN205729815U (en) * | 2016-01-21 | 2016-11-30 | 广州欧诺洁个人护理用品有限公司 | Human body beauty treatment multilayer gel facial film |
| CN206454028U (en) * | 2016-06-01 | 2017-09-01 | 南京天朗制药有限公司 | Body temperature is moulded into type skin nursing film certainly |
| CN107898714A (en) * | 2017-12-28 | 2018-04-13 | 湖南龙丰茯苓科技开发有限公司 | A kind of humidity-preserving type tuckahoe facial mask |
| CN108478468A (en) * | 2018-03-27 | 2018-09-04 | 华南理工大学 | A kind of medical bacteria cellulose/non-woven fabric compounded hydrogel facial mask and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| YAN WU ET AL: "Rapid Allergen Inactivation Using Atomospheric Pressure Cold Plasma", 《ENVIRONMENTAL SCIENCE & TECHNONOGY》 * |
| 刘良 等: "尘螨变应原Der p2基因克隆及原核表达", 《中国媒介生物学及控制杂志》 * |
| 叶帼嫔 等: "低温等离子体活性水对致病菌的作用", 《中国科学：生命科学》 * |
| 国晋菘 等: "大气压低温等离子体的活性氧成分分析及杀菌效应研究", 《北京大学学报（自然科学版）》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022110183A1 (en) * | 2020-11-30 | 2022-06-02 | L'oreal | Mask composition and process |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2552731T3 (en) | Electricity generation particles and their use | |
| JP4984266B2 (en) | Method for producing silver-bonded antibacterial wet wound dressing and wet wound dressing produced by the method | |
| EP1861130B1 (en) | Device and method for treatment of dermatomycosis, and in particular onychomycosis | |
| US20150297782A1 (en) | Nitric oxide-releasing dressings | |
| Lee et al. | One-step fabrication of AgNPs embedded hybrid dual nanofibrous oral wound dressings | |
| TWI702051B (en) | Efficient nano spot lightening, brightening, moisturizing activator and its preparation method | |
| CN104644754A (en) | Traditional Chinese medicine preparation for alleviating visual fatigue and application thereof | |
| JP2002530270A (en) | Multi-action particles for constructing biological media | |
| CN111437221A (en) | Mite-removing free radical hydrogel mask | |
| KR20160069158A (en) | Sericite carbonate beauty pack and the manufacturing method | |
| KR102255431B1 (en) | Microcurrent mask pack including platinum nano | |
| CN110859989A (en) | Liquid band-aid and preparation method thereof | |
| KR101762902B1 (en) | Soluble type fibrous sheet for skin-contacting with optimized dispersibility of skin and usage using the same | |
| WO2021175231A1 (en) | Mask cream, mask patch, mask and method | |
| KR20100133627A (en) | Functional mask for protecting respiratory organs | |
| CN1262093A (en) | Silver foil cosmetics | |
| CN102614544B (en) | Preparation method and application of nano silver antiseptic dressing | |
| RU2426525C1 (en) | Preventive ointment for diabetic foot | |
| CN107595819A (en) | A kind of Nano diamond modified liquid adhesive bandage and preparation method thereof | |
| CN109394614B (en) | Plant beauty dry mask and preparation method thereof | |
| CN112370363A (en) | Nano rare precious metal composite electro-osmosis mask material and preparation method and application thereof | |
| KR20200095645A (en) | Mask pack and manufacturing method thereof | |
| CN114452435B (en) | High-affinity liquid dressing capable of being rapidly effective | |
| CN102058898B (en) | Powder with antibacterial and haemostatic effects and preparation method and applications thereof | |
| KR20070013765A (en) | Cosmetic composition using silicate minerals and cosmetic pack using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200724 |