CN108472313A - 用于治疗耳炎的组合物和方法 - Google Patents

用于治疗耳炎的组合物和方法 Download PDF

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Publication number
CN108472313A
CN108472313A CN201780002919.6A CN201780002919A CN108472313A CN 108472313 A CN108472313 A CN 108472313A CN 201780002919 A CN201780002919 A CN 201780002919A CN 108472313 A CN108472313 A CN 108472313A
Authority
CN
China
Prior art keywords
composition
dmso
pvp
infection
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780002919.6A
Other languages
English (en)
Chinese (zh)
Inventor
约瑟夫·卡普里奥蒂
卡拉·卡普里奥蒂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Veloce Biopharma LLC
Original Assignee
Veloce Biopharma LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/341,930 external-priority patent/US20170071979A1/en
Application filed by Veloce Biopharma LLC filed Critical Veloce Biopharma LLC
Publication of CN108472313A publication Critical patent/CN108472313A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
CN201780002919.6A 2016-11-02 2017-11-01 用于治疗耳炎的组合物和方法 Pending CN108472313A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/341,930 2016-11-02
US15/341,930 US20170071979A1 (en) 2011-05-11 2016-11-02 Composition and method for treating otitis
PCT/US2017/059513 WO2018085384A1 (en) 2016-11-02 2017-11-01 Composition and method for treating otitis

Publications (1)

Publication Number Publication Date
CN108472313A true CN108472313A (zh) 2018-08-31

Family

ID=60860035

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780002919.6A Pending CN108472313A (zh) 2016-11-02 2017-11-01 用于治疗耳炎的组合物和方法

Country Status (5)

Country Link
EP (1) EP3534913A4 (de)
JP (3) JP6255134B1 (de)
KR (3) KR20180061359A (de)
CN (1) CN108472313A (de)
WO (1) WO2018085384A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021161105A (ja) * 2020-03-31 2021-10-11 タイ ミン ファーマシューティカルズ ジェイエスシー ヒト又は動物の慢性若しくは急性のウイルス感染症及び／又は敗血症の予防若しくは治療のための組成物
TW202203946A (zh) * 2020-03-31 2022-02-01 越南商泰明製藥股份有限公司 用於人或動物之慢性或急性之病毒感染症及/或敗血症之預防或治療的組成物
FR3122572A1 (fr) * 2021-05-07 2022-11-11 Nadine GRISLAIN Composition pharmaceutique bioadhésive comprenant du PVPI

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140205559A1 (en) * 2011-05-11 2014-07-24 Alc Therapeutics, Llc Antifungal compositions for the treatment of skin and nails

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241051A (en) * 1977-11-04 1980-12-23 Christie Robert B Calcitonin
US8476319B2 (en) * 2005-03-10 2013-07-02 3M Innovative Properties Company Methods of treating ear infections
DE202005004183U1 (de) * 2005-03-14 2005-05-25 G. Pohl-Boskamp Gmbh & Co. Kg Ohrentropfen zum Einbringen in den Gehörgang
US20060280809A1 (en) * 2005-06-14 2006-12-14 Leshchiner Adele K Anti-infective iodine based compositions for otic and nasal use
CN101002775A (zh) * 2006-01-18 2007-07-25 广州白云山制药股份有限公司广州白云山制药总厂 一种抗感染制剂
GB0709513D0 (en) * 2007-05-17 2007-06-27 Helperby Therapeutics Ltd Topical formulations
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
US20100016450A1 (en) * 2008-07-21 2010-01-21 Otonomy, Inc. Controlled release delivery devices for the treatment of otic disorders
KR20190049931A (ko) * 2009-12-15 2019-05-09 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 무자극성 안과용 포비돈-요오드 조성물
PL2521547T3 (pl) * 2010-01-07 2018-01-31 Univ Minnesota Sposoby i kompozycje do podawania moksyfloksacyny do ucha
ES2391721T3 (es) * 2010-03-01 2012-11-29 Laboratorios Salvat, S.A. Disoluciones acuosas transparentes de acetónido de fluocinolona para el tratamiento de la infamación de oído
TW202023575A (zh) * 2011-09-16 2020-07-01 美商遠景生物製藥股份有限公司 安定之普維酮—碘組成物
US20140271529A1 (en) * 2013-03-14 2014-09-18 Alc Therapeutics, Llc Antifungal compositions for the treatment of secondary skin and nail infections
EP2991638B1 (de) * 2013-05-01 2019-06-26 Neoculi Pty Ltd Verfahren zur behandlung von bakterieninfektionen
KR20180011883A (ko) * 2015-01-20 2018-02-02 벨로체 바이오파르마 엘엘씨 신규한 요오드포 조성물 및 사용 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140205559A1 (en) * 2011-05-11 2014-07-24 Alc Therapeutics, Llc Antifungal compositions for the treatment of skin and nails

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴红丽: "聚维酮碘治疗化脓性中耳炎合并真菌感染的临床特征及其预后影响因素分析", 《中国临床研究》 *
林洪斌: "聚维酮碘治疗外耳道真菌病65例", 《医药导报》 *

Also Published As

Publication number Publication date
WO2018085384A1 (en) 2018-05-11
JP2018070583A (ja) 2018-05-10
EP3534913A4 (de) 2020-07-15
KR20180061359A (ko) 2018-06-07
JP6271804B1 (ja) 2018-01-31
KR20180059554A (ko) 2018-06-04
JP2018070620A (ja) 2018-05-10
JP2018070655A (ja) 2018-05-10
JP6255134B1 (ja) 2017-12-27
EP3534913A1 (de) 2019-09-11
KR20190100442A (ko) 2019-08-28

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Application publication date: 20180831

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