CN108431042A - 抗-il1rap抗体，结合il1rap和cd3的双特异性抗原结合分子及其用途 - Google Patents

抗-il1rap抗体，结合il1rap和cd3的双特异性抗原结合分子及其用途 Download PDF

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Publication number
CN108431042A
CN108431042A CN201680077315.3A CN201680077315A CN108431042A CN 108431042 A CN108431042 A CN 108431042A CN 201680077315 A CN201680077315 A CN 201680077315A CN 108431042 A CN108431042 A CN 108431042A
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China
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seq
il1rap
acid sequence
antibody
amino acid
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Pending
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CN201680077315.3A
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Chinese (zh)
Inventor
B.J.黑里奇
J.F.内梅思
W.K.小尼施奥卡
T.丁
R.M.F.卡多索
D.皮祖蒂
B.斯特拉克
J.费希尔
R.M.阿塔
F.戈代
M.E.萨尔瓦蒂
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Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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Publication of CN108431042A publication Critical patent/CN108431042A/zh
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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CN201680077315.3A 2015-11-02 2016-11-01 抗-il1rap抗体，结合il1rap和cd3的双特异性抗原结合分子及其用途 Pending CN108431042A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562249466P 2015-11-02 2015-11-02
US62/249466 2015-11-02
PCT/US2016/059842 WO2017079121A2 (en) 2015-11-02 2016-11-01 Anti-il1rap antibodies, bispecific antigen binding molecules that bind il1rap and cd3, and uses thereof

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CN108431042A true CN108431042A (zh) 2018-08-21

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TWI781108B (zh) 2016-07-20 2022-10-21 比利時商健生藥品公司 抗ｇｐｒｃ５ｄ抗體、結合ｇｐｒｃ５ｄ與ｃｄ３之雙特異性抗原結合分子及其用途
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EP3489259A1 (en) * 2017-11-23 2019-05-29 Etablissement Français du Sang Anti-il-1rap-car-t cells and their use
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TW202021618A (zh) 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
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