CN108430479A - β-1,3-葡聚糖用于调节免疫功能和治疗肠道炎症的用途 - Google Patents

β-1,3-葡聚糖用于调节免疫功能和治疗肠道炎症的用途 Download PDF

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Publication number
CN108430479A
CN108430479A CN201680076388.0A CN201680076388A CN108430479A CN 108430479 A CN108430479 A CN 108430479A CN 201680076388 A CN201680076388 A CN 201680076388A CN 108430479 A CN108430479 A CN 108430479A
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glucan
euglena
composition
administered
beta
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CN201680076388.0A
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Chinese (zh)
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G·P·霍斯特
R·B·莱文
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Kemin Industries Inc
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Kemin Industries Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/68—Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680076388.0A 2015-10-28 2016-10-27 β-1,3-葡聚糖用于调节免疫功能和治疗肠道炎症的用途 Pending CN108430479A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310424989.8A CN116440154A (zh) 2015-10-28 2016-10-27 用于调节免疫功能和治疗肠道炎症的组合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562247629P 2015-10-28 2015-10-28
US62/247,629 2015-10-28
US201662305875P 2016-03-09 2016-03-09
US62/305,875 2016-03-09
PCT/US2016/059192 WO2017075262A1 (en) 2015-10-28 2016-10-27 Use of beta-1,3-glucan for modulating immune function and treating intestinal inflammation

Related Child Applications (1)

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CN108430479A true CN108430479A (zh) 2018-08-21

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CN202310424989.8A Pending CN116440154A (zh) 2015-10-28 2016-10-27 用于调节免疫功能和治疗肠道炎症的组合物

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US (3) US10912794B2 (cg-RX-API-DMAC7.html)
EP (1) EP3368049A4 (cg-RX-API-DMAC7.html)
JP (4) JP2018531977A (cg-RX-API-DMAC7.html)
CN (2) CN108430479A (cg-RX-API-DMAC7.html)
AU (1) AU2016344136B2 (cg-RX-API-DMAC7.html)
WO (1) WO2017075262A1 (cg-RX-API-DMAC7.html)

Cited By (5)

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CN111544592A (zh) * 2020-03-13 2020-08-18 中山大学附属第一医院 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用
WO2020249132A1 (zh) * 2019-06-13 2020-12-17 青岛海洋生物医药研究院股份有限公司 一种葡聚糖在制备药物的应用
WO2020249133A1 (zh) * 2019-06-14 2020-12-17 青岛海洋生物医药研究院股份有限公司 一种β-葡聚糖组合物及其用途
CN114668816A (zh) * 2022-02-23 2022-06-28 如新(中国)日用保健品有限公司 一种含铁皮石斛提取物的组合物及其应用
CN115746163A (zh) * 2022-11-07 2023-03-07 中国海洋大学 一种硫酸化β-葡聚糖、制备方法及其在免疫保护及抗肿瘤药物中的应用

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EP3368049A4 (en) * 2015-10-28 2019-07-03 Kemin Industries, Inc. USE OF BETA-1,3-GLUCAN FOR MODULATING THE IMMUNE FUNCTION AND TREATING A DARM IGNITION
WO2018222581A1 (en) * 2017-05-29 2018-12-06 Resinnate Therapeutics Llc Methods and formulations for administering beta glucan
JP7013754B2 (ja) * 2017-09-15 2022-02-01 株式会社三洋物産 遊技機
JP7013753B2 (ja) * 2017-09-15 2022-02-01 株式会社三洋物産 遊技機
JP7120561B2 (ja) * 2017-12-04 2022-08-17 国立研究開発法人産業技術総合研究所 糖及び／又は脂質の代謝改善剤
JP7162542B2 (ja) * 2018-01-25 2022-10-28 株式会社ユーグレナ 食品因子センシング関連遺伝子発現促進用食品組成物及び食品因子センシング関連遺伝子発現促進剤
CN110115328A (zh) * 2018-02-06 2019-08-13 美国朗智生物科技集团 一种含有眼虫藻、姜黄和天然菊粉的饮料及其制备方法
KR102801517B1 (ko) * 2020-02-19 2025-04-25 케민 인더스트리즈, 인코포레이티드 용해성 베타 글루칸의 조성물 및 관련 방법
DE102020125873A1 (de) * 2020-10-02 2022-04-07 Dr. Kurt Wolff Gmbh & Co. Kg Zusammensetzung zur Behandlung von Haaren und der Kopfhaut
JP7813518B2 (ja) * 2021-02-04 2026-02-13 株式会社神鋼環境ソリューション 細胞間接着保護剤
JP2021079226A (ja) * 2021-03-01 2021-05-27 株式会社三洋物産 遊技機
KR102789389B1 (ko) * 2022-01-04 2025-04-04 전남대학교 산학협력단 베타글루칸 가수분해물을 포함하는 면역 기능 증진용 식품 조성물 및 이의 제조 방법
CN117467722B (zh) * 2023-11-01 2025-02-11 武汉诺见生物技术有限公司 一种从酿酒酵母细胞发酵液中提纯β-1,3-葡聚糖的新工艺
WO2025138017A1 (zh) * 2023-12-28 2025-07-03 清华大学 昆布及其活性成分在制备治疗高果糖促进的结肠炎相关结直肠癌的药物中的应用
CN120531129A (zh) * 2024-02-22 2025-08-26 嘉兴泽元生物制品有限责任公司 一种裸藻及其产物在改善高尿酸血症中的应用

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020249132A1 (zh) * 2019-06-13 2020-12-17 青岛海洋生物医药研究院股份有限公司 一种葡聚糖在制备药物的应用
CN114026129A (zh) * 2019-06-13 2022-02-08 正大制药（青岛）有限公司 一种葡聚糖在制备药物的应用
US12357654B2 (en) 2019-06-13 2025-07-15 Qingdao Conson Pharmaceutical Co., Ltd. Application of glucan in preparation of drug
WO2020249133A1 (zh) * 2019-06-14 2020-12-17 青岛海洋生物医药研究院股份有限公司 一种β-葡聚糖组合物及其用途
CN114008083A (zh) * 2019-06-14 2022-02-01 正大制药（青岛）有限公司 一种β-葡聚糖组合物及其用途
US12533373B2 (en) 2019-06-14 2026-01-27 Qingdao Conson Pharmaceutical Co., Ltd. β-glucan composition and use therefor
CN111544592A (zh) * 2020-03-13 2020-08-18 中山大学附属第一医院 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用
CN111544592B (zh) * 2020-03-13 2022-05-03 中山大学附属第一医院 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用
CN114668816A (zh) * 2022-02-23 2022-06-28 如新(中国)日用保健品有限公司 一种含铁皮石斛提取物的组合物及其应用
CN115746163A (zh) * 2022-11-07 2023-03-07 中国海洋大学 一种硫酸化β-葡聚糖、制备方法及其在免疫保护及抗肿瘤药物中的应用

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JP2025060946A (ja) 2025-04-10
EP3368049A4 (en) 2019-07-03
CA3003330A1 (en) 2017-05-04
US20180311271A1 (en) 2018-11-01
BR112018008401A2 (pt) 2018-10-23
JP2018531977A (ja) 2018-11-01
AU2016344136B2 (en) 2021-11-11
US11744847B2 (en) 2023-09-05
EP3368049A1 (en) 2018-09-05
WO2017075262A1 (en) 2017-05-04
JP2021120383A (ja) 2021-08-19
AU2016344136A1 (en) 2018-05-10
CN116440154A (zh) 2023-07-18
US10912794B2 (en) 2021-02-09
US20210346423A1 (en) 2021-11-11
US20240000825A1 (en) 2024-01-04
JP2023052414A (ja) 2023-04-11

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