CN108420933A - A kind of composition and preparation method thereof for treating extreme misery burn - Google Patents
A kind of composition and preparation method thereof for treating extreme misery burn Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
Abstract
The composition of the treatment extreme misery burn of the present invention, including following parts by weight of component：60 80 parts of Conyza canadensis, 10 20 parts of rheum officinales, 40 50 parts of Semen Lactucae sativae oil, 5 10 parts of willow barks, 10 20 parts of rabbit hair ashes, 10 15 parts of glossy privet leaves, 10 20 portions of aloes, 35 portions of cactuses and 23 portions of lavenders；It using Conyza canadensis as key component, is combined with other each components, plays rapid hemostasis and pain-relieving, reduces sepage, cytothesis, the surface of a wound is promoted to heal rapidly, burns scar is reduced, for slight and moderate burn, after use, substantially without scar after treatment.The preparation method of the treatment extreme misery burn, adjusts preparation process according to each component of the composition, the drug effect of each component is enable to give full play to and coordinate, and prepares the composition of therapeutic effect treatment extreme misery burn outstanding.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of composition and preparation method thereof for treating extreme misery burn.
Background technology
Extreme misery burn refers to that comburant and scorching hot liquid, solid, gas and electric current etc. directly act on human body, is caused
Skin is scalded or burn.It is often accompanied by flush oedema, the skins such as a large amount of sepages in surface and injury redness cusalgia, blistering, incrustation
Skin damages class disease.Less serious case undermines fur, and severe one injures in muscle muscle, or even occurs suffering a shock or breathe, heartbeat pause.Scald root
According to scalding area and depth, it is divided into mild burn, moderate burn, severe burn and Extra severe burn, wherein if burn site has depth
If Ι Ι degree is scalded and Ι Ι Ι degree scald without treating and handling in time, the wound repair of Chang Liuyou scars, Ι Ι Ι degree scald relies on
In surgery skin grafting or Vessel Skin Flap, serious and person needs amputation.
Burn wound after the treatment of modern Chinese medicine therapy, still has scar apparent, and the defect of healing time section.
Invention content
Based on problem above, one purpose of the invention, which is to provide one kind, to be burnt with rapid healing extreme misery, reduce burn
The composition of scar.
A further object is the concrete component based on the composition, and formulating one kind can be such that each component is more preferably used in combination,
Embody the preparation method of each component optimal treatment effect.
The technical scheme is that：
The present invention provides a kind of composition for treating extreme misery burn, including following parts by weight of component：60-80 parts of Conyza canadensis,
10-20 parts of rheum officinales, 40-50 parts of Semen Lactucae sativae oil, 5-10 parts of willow barks, 10-20 parts of rabbit hair ashes, 10-15 parts of glossy privet leaves, 10-20
Part aloe, 3-5 portions of cactuses and 2-3 portions of lavenders.
The composition of the above corresponding parts by weight of component is combined using Conyza canadensis as key component with other each components, is played fast
Short stopping blood and relieving pain reduces sepage, and cytothesis, the surface of a wound is promoted to heal rapidly, reduces burns scar.Conyza canadensis has clearing heat and promoting diuresis
The effect of, play the role of main hemostasis, analgesic in the composition of the application and eliminates scar；Rheum officinale removing pattogenic heat from the blood and toxic material from the body, by
Stasis of blood promoting menstruation；Semen Lactucae sativae oil reconciliation each component, while the impervious liquid that effectively stops blooding；Rabbit hair ash removing necrosis, promoting granulation anti-inflammatory analgetic；Willow bark stops
Damaged cell is repaired in pain anti-inflammatory；Aloe and cactus play the role of hemostasis, antibacterial and repair skin；Lavender is sterilized, and helps
Skin heals.
Preferably, the composition of the treatment extreme misery burn, including following parts by weight of component：It is 70 parts of Conyza canadensis, 15 parts big
Huang, 45 parts of Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 portions of aloes, 4 portions of cactuses and 3 parts smoke clothing
Grass.
The above component can be directly prepared into and be mixed and made into pulvis, with the composition and water with 1:The big baked wheaten cake of weight ratio of 3-4
It opens 1 minute, is cooled to 30 DEG C hereinafter, soaked with towel, spreads on affected part.Three times a day, the generally rear painless sepage in affected part for three days on end
Phenomenon of bleeding is substantially reduced, or even disappears, different because burning degree.
The present invention provides the preparation method of the composition of the above treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 30-40min into saturated salt solution, obtain lavender extraction
Take liquid；By the lavender extract liquor through supercritical CO2Extraction, obtain lavender extract, by the lavender extract into
Row distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:150-180, extraction temperature 50-
55 DEG C, pressure 25-28MPa, time 1-2h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender exists
It is impregnated in saturated salt solution, extraction efficiency is made to improve, extraction yield improves；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, are obtained described
Treat the composition of extreme misery burn.
Method made above, by each component pre-process spare to the composition is finally mixed and made into respectively, makes each
Component fully combines, and plays hemostasis and pain-relieving, promotes skin repair regeneration, reduces burns scar.
Further, the composition of the described treatment extreme misery burn, further includes 5-10 parts of peach barks, peach bark nature and flavor are sweet,
Pungent, flat, the hemostasis, impervious liquid effect after peach bark addition are more preferable, and healing time shortens.The combination of the treatment extreme misery burn
The preparation method of object, includes the following steps：
(1) rheum officinale, willow bark, peach bark, glossy privet leaf are milled, and spare in immersion Semen Lactucae sativae oil, soaking temperature maintains
20 DEG C hereinafter, holding wherein each component drug effect, obtains the first mixture；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 30-40min into saturated salt solution, obtain lavender extraction
Take liquid；By the lavender extract liquor through supercritical CO2Extraction, obtain lavender extract, by the lavender extract into
Row distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:150-180, extraction temperature 50-
55 DEG C, pressure 25-28MPa, time 1-2h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender exists
It is impregnated in saturated salt solution, extraction efficiency is made to improve, extraction yield improves；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, are obtained described
Treat the composition of extreme misery burn.
Further, the composition of the treatment extreme misery burn, further includes 3-5 portions of tealeaves, and swelling and pain relieving effect is more preferable,
Healing time significantly further shortens.
Preferably, the composition of the treatment extreme misery burn, including following parts by weight of component：70 parts of Conyza canadensis, 15 parts
Rheum officinale, 45 parts of Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 portions of aloes, 4 portions of cactuses, 3 parts smoke
Clothing grass, 8 parts of peach barks and 4 portions of tealeaves.
The preparation method of the composition of the treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 30-40min into saturated salt solution, obtain lavender extraction
Take liquid；By the lavender extract liquor through supercritical CO2Extraction, obtain lavender extract, by the lavender extract into
Row distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:150-180, extraction temperature 50-
55 DEG C, pressure 25-28MPa, time 1-2h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender exists
It is impregnated in saturated salt solution, extraction efficiency is made to improve, extraction yield improves；
(4) peach bark is carbonized, powder processed, decoction tanning 2-3 hours is added to the water together with tealeaves, tanning temperature is 150-
180 DEG C, obtain third mixture；
(5) first mixture, the second mixture, third mixture, Lavender and rabbit hair ash are mixed equal
It is even, obtain the composition of the treatment extreme misery burn.
Adult's mild burn：The gross area is in 10% II degree burn and I degree burn below；
Moderate burn：The gross area is in 11-30% or III degree burn surface area in 10% burn below.
Children's mild burn：The gross area is in 5% II degree burn and I degree burn below；
Moderate burn：The gross area is burnt in the II degree of 5-15% or III degree burn surface area is in 5% burn below.
The present invention technique effect be：
The composition of the treatment extreme misery burn of the present invention is combined with other each components, is played using Conyza canadensis as key component
Rapid hemostasis and pain-relieving reduces sepage, promotes cytothesis, the surface of a wound to heal rapidly, reduces burns scar, is burnt for slight and moderate
Hinder patient, after use, substantially without scar after treatment.
The preparation method adjusts preparation process according to each component of the composition, enables the drug effect of each component
It gives full play to and coordinates, prepare the composition of therapeutic effect treatment extreme misery burn outstanding.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, technical scheme of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Following embodiment is with 1 part for 1g.
Embodiment 1
A kind of composition for treating extreme misery burn, including following parts by weight of component：70 parts of Conyza canadensis, 15 parts of rheum officinales, 45 parts
Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 portions of aloes, 4 portions of cactuses and 3 portions of lavenders.
The present invention provides the preparation method of the composition of the above treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash 5 DEG C or less refrigerate it is spare, for the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 30min into saturated salt solution, obtain lavender extraction
Liquid；By the lavender extract liquor through supercritical CO2Extraction, obtains lavender extract, and the lavender extract is carried out
Distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:180, extraction temperature is 50 DEG C, pressure
For 28MPa, time 1h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender is soaked in saturated salt solution
Bubble, makes extraction efficiency improve, and extraction yield improves；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, are obtained described
Treat the composition of extreme misery burn.
Embodiment 2
A kind of composition for treating extreme misery burn, including following parts by weight of component：60 parts of Conyza canadensis, 20 parts of rheum officinales, 40 parts
Semen Lactucae sativae oil, 10 parts of willow barks, 10 parts of rabbit hair ashes, 15 parts of glossy privet leaves, 10 portions of aloes, 5 portions of cactuses, 2 portions of lavenders and 10
Part peach bark.
The present invention provides the preparation method of the composition of the above treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, peach bark, glossy privet leaf are milled, and spare in immersion Semen Lactucae sativae oil, soaking temperature maintains
20 DEG C hereinafter, holding wherein each component drug effect, obtains the first mixture；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 40min into saturated salt solution, obtain lavender extraction
Liquid；By the lavender extract liquor through supercritical CO2Extraction, obtains lavender extract, and the lavender extract is carried out
Distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:150, extraction temperature is 55 DEG C, pressure
For 25MPa, time 2h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender is soaked in saturated salt solution
Bubble, makes extraction efficiency improve, and extraction yield improves；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, are obtained described
Treat the composition of extreme misery burn.
Embodiment 3
A kind of composition for treating extreme misery burn, including following parts by weight of component：80 parts of Conyza canadensis, 10 parts of rheum officinales, 50 parts
Semen Lactucae sativae oil, 5 parts of willow barks, 20 parts of rabbit hair ashes, 10 parts of glossy privet leaves, 20 portions of aloes, 3 portions of cactuses, 3 portions of lavenders, 5 portions of peaches
Bark and 5 portions of tealeaves.
The preparation method of the composition of the treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 35min into saturated salt solution, obtain lavender extraction
Liquid；By the lavender extract liquor through supercritical CO2Extraction, obtains lavender extract, and the lavender extract is carried out
Distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:160, extraction temperature is 52 DEG C, pressure
For 26MPa, time 1.5h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender is in saturated salt solution
It impregnates, extraction efficiency is made to improve, extraction yield improves；
(4) peach bark being carbonized, powder processed, decoction tanning 2 hours is added to the water together with tealeaves, tanning temperature is 160 DEG C,
Obtain third mixture；
(5) first mixture, the second mixture, third mixture, Lavender and rabbit hair ash are mixed equal
It is even, obtain the composition of the treatment extreme misery burn.
Embodiment 4
A kind of composition for treating extreme misery burn, including following parts by weight of component：70 parts of Conyza canadensis, 15 parts of rheum officinales, 45 parts
Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 portions of aloes, 4 portions of cactuses, 3 portions of lavenders, 8 portions of peaches
Bark and 4 portions of tealeaves.
The preparation method of the composition of the treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 30min into saturated salt solution, obtain lavender extraction
Liquid；By the lavender extract liquor through supercritical CO2Extraction, obtains lavender extract, and the lavender extract is carried out
Distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:160, extraction temperature is 50 DEG C, pressure
For 25MPa, time 1h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender is soaked in saturated salt solution
Bubble, makes extraction efficiency improve, and extraction yield improves；
(4) peach bark being carbonized, powder processed, decoction tanning 2 hours is added to the water together with tealeaves, tanning temperature is 180 DEG C,
Obtain third mixture；
(5) first mixture, the second mixture, third mixture, Lavender and rabbit hair ash are mixed equal
It is even, obtain the composition of the treatment extreme misery burn.
Embodiment 5
A kind of composition for treating extreme misery burn, including following parts by weight of component：70 parts of Conyza canadensis, 10 parts of rheum officinales, 40 parts
Semen Lactucae sativae oil, 10 parts of willow barks, 10 parts of rabbit hair ashes, 10 parts of glossy privet leaves, 10 portions of aloes, 3 portions of cactuses, 2 portions of lavenders, 10 parts
Peach bark and 3 portions of tealeaves.
The preparation method of the composition of the treatment extreme misery burn, includes the following steps：
(1) rheum officinale, willow bark, glossy privet leaf milling, immerse Semen Lactucae sativae oil in it is spare, soaking temperature maintain 20 DEG C with
Under, wherein each component drug effect is kept, the first mixture is obtained；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added and impregnates 40min into saturated salt solution, obtain lavender extraction
Liquid；By the lavender extract liquor through supercritical CO2Extraction, obtains lavender extract, and the lavender extract is carried out
Distillation, obtains Lavender；Lavender powder and the weight ratio of saturated salt solution are 1:180, extraction temperature is 50 DEG C, pressure
For 25MPa, time 2h, extraction temperature is unsuitable excessively high, otherwise can destroy its active ingredient, lavender is soaked in saturated salt solution
Bubble, makes extraction efficiency improve, and extraction yield improves；
(4) peach bark being carbonized, powder processed, decoction tanning 3 hours is added to the water together with tealeaves, tanning temperature is 180 DEG C,
Obtain third mixture；
(5) first mixture, the second mixture, third mixture, Lavender and rabbit hair ash are mixed equal
It is even, obtain the composition of the treatment extreme misery burn.
Experimental example
Experimental subjects：
The patient of 75 different burn degree, wherein including
Burn 24 people of I degree, shallow 21 people of II degree, 15 people of depth II degree, and the burn gross area of the above fire victim is no more than 30%；
The burn surface area of 15 people of III degree, III degree fire victims are no more than 5%.
Above 75 fire victims belong to slight or moderate burn patient.
Composition to treat extreme misery burn made from 1-3 of the embodiment of the present invention is treated, and every group includes burn I degree 8
People, shallow 7 people of II degree, 5 people of depth II degree, 5 people of III degree, spread on affected part, daily dressing 3 times.
Experimental result：
Following result is shown not stay the fire victim's quantity and action curative day of scar after the composition treatment.
Table 1
By with the experimental result of upper table 1 it is found that the embodiment of the present invention 1-3 controlling for I degree and shallow II degree fire victim
Therapeutic effect reaches 100% and does not stay scar, and healing time significantly shortens after peach bark and tealeaves is added, and deep ii degree burn patient is not
Keliod patients are stayed to increase, healing time shortens；The healing time of the more conventional drug therapy of healing time of III degree fire victims is bright
It is aobvious to shorten.
Typical case
Field, man, 20 years old, cook was accidentally scalded by hot water in the course of work, and part is red and swollen, hence it is evident that bubble, with this hair
After bright composition is treated one day, hence it is evident that analgesic is cured, no scar after 3 days.
Mr. Wang, female, 35 years old, worker, accidentally by fire wound, hospital diagnosis was deep ii degree burn, used the group of the present invention
It closes object to treat 1 day, pain symptom mitigates, 3 days, and sepage symptom mitigates, and is continuing with, and after 12 days, affected part incrustation falls off, 2 months
After check, no scar.
Lee, man, 15 years old, student injured foot's muscles and bones, III degree burn, area is about 3%, uses this by fire wound
The composition of invention is treated 1 day, is slugged symptom and is mitigated, and after 5 days, sepage symptom mitigates, and is continuing with 20 days surface of a wound and is restored complete,
It is checked after 3 months, burns the only colour of skin at double and whiten, no clear scar hyperplasia.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of composition for treating extreme misery burn, which is characterized in that including following parts by weight of component：60-80 parts of Conyza canadensis,
10-20 parts of rheum officinales, 40-50 parts of Semen Lactucae sativae oil, 5-10 parts of willow barks, 10-20 parts of rabbit hair ashes, 10-15 parts of glossy privet leaves, 10-20
Part aloe, 3-5 portions of cactuses and 2-3 portions of lavenders.
2. the composition for the treatment of extreme misery burn according to claim 1, which is characterized in that including following parts by weight of component：
70 parts of Conyza canadensis, 15 parts of rheum officinales, 90 parts of Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 parts of aloes, 4
Part cactus and 3 portions of lavenders.
3. the composition for the treatment of extreme misery burn according to claim 1, which is characterized in that further include 5-10 parts of peach barks.
4. the composition for the treatment of extreme misery burn according to claim 1, which is characterized in that further include 3-5 portions of tealeaves.
5. the composition for the treatment of extreme misery burn according to claim 3, which is characterized in that including following parts by weight of component：
70 parts of Conyza canadensis, 15 parts of rheum officinales, 90 parts of Semen Lactucae sativae oil, 8 parts of willow barks, 15 parts of rabbit hair ashes, 12 parts of glossy privet leaves, 15 parts of aloes, 4
Part cactus, 3 portions of lavenders, 8 parts of peach barks and 4 portions of tealeaves.
6. the preparation method of the composition for the treatment of extreme misery burn described in claim 1, which is characterized in that include the following steps：
(1) rheum officinale, willow bark, glossy privet leaf are milled, spare in immersion Semen Lactucae sativae oil, are the first mixture；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added into saturated salt solution and impregnates, obtains lavender extract liquor；It will be described
Lavender extract liquor is through supercritical CO2Extraction, obtains lavender extract, the lavender extract is distilled, is obtained
Lavender；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, obtain the treatment
The composition of extreme misery burn.
7. the preparation method of the composition of the treatment extreme misery burn described in claim 3, which is characterized in that include the following steps：
(1) rheum officinale, willow bark, peach bark, glossy privet leaf are milled, spare in immersion Semen Lactucae sativae oil, are the first mixture；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added into saturated salt solution and impregnates, obtains lavender extract liquor；It will be described
Lavender extract liquor is through supercritical CO2Extraction, obtains lavender extract, the lavender extract is distilled, is obtained
Lavender；
(4) first mixture, the second mixture, Lavender and rabbit hair ash are uniformly mixed, obtain the treatment
The composition of extreme misery burn.
8. the preparation method of the composition of the treatment extreme misery burn described in claim 4, which is characterized in that include the following steps：
(1) rheum officinale, willow bark, glossy privet leaf are milled, spare in immersion Semen Lactucae sativae oil, are the first mixture；
(2) cactus deburring, then same Conyza canadensis, aloe mixing, mash it is spare, be the second mixture；
(3) lavender powder is made in lavender, is added into saturated salt solution and impregnates, obtains lavender extract liquor；It will be described
Lavender extract liquor is through supercritical CO2Extraction, obtains lavender extract, the lavender extract is first distilled, is obtained
To Lavender；
(4) peach bark is carbonized, powder processed, decoction tanning is added to the water together with tealeaves, obtains third mixture；
(5) first mixture, the second mixture, third mixture, Lavender and rabbit hair ash are uniformly mixed, are obtained
To the composition of the treatment extreme misery burn.
9. according to any preparation methods of claim 6-8, which is characterized in that in step (3), lavender powder with it is full
Weight ratio with saline solution is 1:150-180, soaking time 30-40min, extraction temperature are 50-55 DEG C, pressure 25-
28MPa, time 1-2h.
10. preparation method according to claim 8, which is characterized in that in step (4), tanning temperature is 150-180
DEG C, the time is 2-3 hours.
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| EP4324471A1 (en) | 2022-08-15 | 2024-02-21 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Compositions for use in the prevention or treatment of oral or dental disorders or dysfunctions |
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| CN111990720A (en) * | 2020-08-27 | 2020-11-27 | 烟台理松安全科技有限公司 | Mask fabric with auxiliary burn treatment function and preparation method thereof |
| EP4324471A1 (en) | 2022-08-15 | 2024-02-21 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Compositions for use in the prevention or treatment of oral or dental disorders or dysfunctions |
| WO2024037841A1 (en) | 2022-08-15 | 2024-02-22 | Universitätsmedizin Der Johannes Gutenberg-Universität Mainz | Compositions for use in the prevention or treatment of oral or dental disorders or dysfunctions |
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Application publication date: 20180821 |