CN113209167A - Traditional Chinese medicine composition for treating burn tissue scar - Google Patents

Traditional Chinese medicine composition for treating burn tissue scar Download PDF

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CN113209167A
CN113209167A CN202110644400.6A CN202110644400A CN113209167A CN 113209167 A CN113209167 A CN 113209167A CN 202110644400 A CN202110644400 A CN 202110644400A CN 113209167 A CN113209167 A CN 113209167A
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traditional chinese
chinese medicine
medicine composition
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王洪全
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12Magnesium silicate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/32Manganese; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating burn tissue scars, and relates to a traditional Chinese medicine composition for treating burn tissue scars. The invention aims to solve the problems that the existing medicine for treating burn has slow curative effect, patients feel pain in the treatment process, and scars are left on the burn wound surface. The traditional Chinese medicine composition for treating the burn tissue scar consists of 5-40 parts by weight of cinnabar, 15-45 parts by weight of borneol, 40-80 parts by weight of gypsum, 5-20 parts by weight of pyrolusite, 5-15 parts by weight of indigo naturalis and 5-25 parts by weight of jade scurf. The invention is used for treating burn tissue scar.

Description

Traditional Chinese medicine composition for treating burn tissue scar
Technical Field
The invention relates to a traditional Chinese medicine composition for treating burn tissue scars.
Background
Burns are tissue injuries caused by heat, and the clinical manifestations are mainly skin redness, blisters, pain, etc. Burns often occur on the body surface, including the skin, subcutaneous tissue, muscles, etc. According to the clinical manifestations of pathogens of burn, the traditional Chinese medicine considers that a large amount of tissue necrosis exists in the formation of a wound surface; the difficulty in activating blood and dissolving stasis, and the toxicity caused by heat-induced stasis and stasis are the main reasons for difficult healing. Particularly fire burn, the smoke of the fire burn carries high-temperature gas and particles, and the human body can burn the respiratory tract after being inhaled, so that the tissue edema, the secretion increase, the respiratory tract blockage and the asphyxia are caused; the burned tissue may have necrosis, body fluid exudation, tissue edema and degeneration, damage to the epidermis hair growing layer and dermis living tissue, necrosis, small area superficial burn, and little body fluid exudation, and does not affect the whole body blood circulation. In extensive or deep burns, massive fluid exudation can lead to shock and infection, damage to blood cells, even charring of the cortex, and associated sepsis, leading to multiple organ dysfunction.
According to the body manifestation, pathological change and symptoms of the burned surface, the formation of blisters with different sizes on the surface caused by burning is caused, the blisters contain faint yellow clear liquid, and if the blister skin is peeled off, the wound surface is ruddy, moist and obvious in pain. The wound surface is slightly wet, alternate red and white, and the pain sensation is mild and dull. Full-thickness skin burns can reach deep into muscles and even bones. The wound surface wax is white or brown, even carbonized, hard like leather, dry, without seepage, and the acupuncture and the hair removal have no pain sense, and the subcutaneous blood vessels burst, so that the function of each organ of the viscera is disturbed, and the labor capacity of the patient is lost. At present, the medicines for treating the burn disease comprise various medicines such as traditional Chinese medicines, western medicines and mixed medicines. The treatment effect is not satisfactory for the patient.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for treating burn tissue scars, aiming at solving the problems that the existing medicine for treating burn has slow curative effect, patients feel pain in the treatment process and scars are left on the burn wound surface.
The invention relates to a traditional Chinese medicine composition for treating burn tissue scar, which comprises, by weight, 5-40 parts of cinnabar, 15-45 parts of borneol, 40-80 parts of gypsum, 5-20 parts of pyrolusite, 5-15 parts of indigo naturalis and 5-25 parts of jade scraps.
The invention has the beneficial effects that:
the traditional Chinese medicine formula can promote the wound to heal quickly, form comprehensive protection on the wound due to large-area necrotic tissues caused by burn wound, prevent wound infection, prevent scars left after burn and achieve the purpose of comprehensively healing the burn.
Detailed Description
The first embodiment is as follows: the traditional Chinese medicine composition for treating the burn tissue scar consists of 5-40 parts by weight of cinnabar, 15-45 parts by weight of borneol, 40-80 parts by weight of gypsum, 5-20 parts by weight of pyrolusite, 5-15 parts by weight of natural indigo and 5-25 parts by weight of jade scraps.
The medicine of the embodiment has proper compatibility and reasonable formula, and the effects of the medicines are as follows:
cinnabar: sweet in flavor, slightly cold in nature, entering heart meridian. The efficacy application is as follows: relieving mental uneasiness, invigorating qi, improving eyesight, promoting blood circulation, relieving vexation, relieving diabetes, treating diseases, and eliminating insect sore.
Borneol: pungent and bitter in flavor, warm in nature, non-toxic, and entering lung and liver meridians. The efficacy application is as follows: it can be used for treating pathogenic qi accumulation in heart and abdomen, pharyngitis, tonsillitis, tongue swelling, hemorrhoid, infantile convulsion, phlegm stagnation in adult, nine orifices, pathogenic wind, eyesight and hearing impairment, parasites killing, and toxic materials due to parasitic diseases.
Gypsum: pungent and sweet in flavor, slightly cold in nature and entering lung and stomach meridians. The efficacy application is as follows: it can be used for treating asthma due to lung heat, headache, etc., and has effects in clearing away heat, purging pathogenic fire, promoting perspiration, relieving muscles and muscles, invigorating spleen, invigorating qi, promoting salivation, quenching thirst, clearing away lung-heat, and eliminating phlegm.
The unknown is as follows: sweet in flavor, neutral in nature and entering liver meridian. The efficacy application is as follows: mainly treats the internal injury of incised wound, promotes blood circulation, stops bleeding, reduces swelling, relieves pain and promotes tissue regeneration.
Indigo naturalis: sweet and salty in flavor, cold in nature and entering liver and lung meridians. The efficacy application is as follows: can be used for treating stomach heat, epilepsy, sore throat, aphtha, pyocutaneous disease, toxic heat, speckle, hematemesis, epistaxis, hematemesis, and epistaxis, cooling blood, stopping bleeding, cooling blood, removing speckle, and clearing away heat and toxic materials.
Jade scraps: sweet in flavor, neutral in nature, and entering lung meridian. The efficacy application is as follows: relieving restlessness, quenching thirst, tranquilizing mind, relieving convulsion, reducing scar, promoting voice and throat, and caring skin.
The embodiment follows the principle of the formula of 'monarch, minister, assistant and guide' in traditional Chinese medicine, all the components are from the medicines collected in China (pharmacopoeia), and the traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, regulating qi and blood, clearing and activating the channels and collaterals, and improving skin tissue microcirculation so as to treat burn and have no scar. Has obvious curative effect, no toxic side effect and convenient treatment of the medicinal preparation.
The preferred components of the traditional Chinese medicine in the embodiment meet the regulation of the Chinese people's republic of China medicine management method, and the comprehensive effect of the traditional Chinese medicines is utilized to treat burn, so that the traditional Chinese medicine is non-toxic and harmless to human bodies.
Animal experiments prove that the medicine can completely and comprehensively cure the diseases by the curative effect without scar, and the medicine is proved to be safe and reliable.
The traditional Chinese medicine preparation of the embodiment can effectively treat burn and achieve the effect of reducing scars on the burn. Particularly, the healing of the wound surface is quickly cured by enhancing the respective treatment characteristics of the medicines through the mutual cooperation of the medicines and improving the self immune function of the human body, so that the rehabilitation effect is better achieved.
The second embodiment is as follows: the first difference between the present embodiment and the specific embodiment is: the traditional Chinese medicine composition for treating the burn tissue scar consists of 20-30 parts by weight of cinnabar, 20-40 parts by weight of borneol, 50-70 parts by weight of gypsum, 10-15 parts by weight of pyrolusite, 10-15 parts by weight of indigo naturalis and 10-20 parts by weight of jade scurf. The rest is the same as the first embodiment.
The third concrete implementation mode: the present embodiment differs from the first or second embodiment in that: the traditional Chinese medicine composition for treating the burn tissue scar consists of 25 parts by weight of cinnabar, 30 parts by weight of borneol, 60 parts by weight of gypsum, 10 parts by weight of pyrolusite, 10 parts by weight of natural indigo and 15 parts by weight of jade scurf. The others are the same as in the first or second embodiment.
The fourth concrete implementation mode: the difference between this embodiment mode and one of the first to third embodiment modes is: the traditional Chinese medicine composition for treating the burn tissue scar is prepared into powder. The rest is the same as one of the first to third embodiments.
The fifth concrete implementation mode: the difference between this embodiment and one of the first to fourth embodiments is: the traditional Chinese medicine composition for treating the burn tissue scar is prepared into an ointment. The rest is the same as one of the first to fourth embodiments.
The following examples were used to demonstrate the beneficial effects of the present invention:
example 1:
weighing the following Chinese medicinal materials in parts by weight:
20 parts of cinnabar, 25 parts of borneol, 50 parts of gypsum, 10 parts of pyrolusite, 10 parts of indigo naturalis and 10 parts of jade scurf.
The preparation process of the embodiment is as follows: the medicinal materials are prepared into bagged powder according to a conventional powder preparation method.
Example 2:
weighing the following Chinese medicinal materials in parts by weight:
30 parts of cinnabar, 35 parts of borneol, 50 parts of gypsum, 15 parts of pyrolusite, 15 parts of indigo naturalis and 15 parts of jade scurf.
The preparation process of the embodiment is as follows: the raw materials are prepared into the ointment according to the conventional preparation method for preparing the ointment.
The basis of diagnosis is as follows:
the classification of the severity of the burn is classified by the body surface area of the whole body (TBSA, body surface area of the whole body) and the depth of the burn. The position, size and depth of the root burn can be used for determining the treatment mode, judging the prognosis and the like.
Among these, discrimination of burn depth is critical to the assessment. The body surface area can be calculated as the palm size occupying 1% of the body surface area.
I degree burn: only the superficial layer of epidermis is injured, and the hair growth layer is healthy. A red, blotchy, dry, burning sensation on the surface. The regeneration capacity is strong, the desquamation can be cured within 3-7 days, and pigmentation can be caused in a short period.
Superficial II degree burn: the germinal layer and dermal papilla layer of epidermis are injured, and are formed with blisters of different sizes, which contain faint yellow clear liquid, and the blisters are stripped, and the wound surface is ruddy, moist and painful.
The wound surface is regenerated and repaired by the residual epidermis hair growing layer and the epithelium of skin attachments (sweat glands and hair follicles), if the wound surface is not infected, the wound surface can be healed within 1-2 weeks, no scar is generally left, but most of the wound surface is colored and hyperpigmented.
Deep II degree burn: the part of the reticular layer below the papillary layer of the dermis is injured, but the part of the reticular layer is remained, the depth is not consistent, and blisters can be formed, but after the blisters are removed, the wound surface is slightly wet, red and white are alternated, and the pain sensation is dull.
Because the residual skin attachments are in the dermis layer, the wound surface repair can form an epithelial island by the proliferation of the epithelium, and the wound surface repair can be fused and repaired for 3-4 weeks if no infection exists. But often scar hyperplasia.
III degree burn: the whole skin burn, also called eschar type burn, can reach deep into muscles, even bones, internal organs, etc. White or brown wound surface wax, even charred, hard like leather, dry, no liquid seepage, cool hair, no pain sensation during acupuncture and hair removal. The dendritic vascular network of the coarse emboli (subdermal vascular plexus emboli) is visible.
Because the skin and the accessories thereof are completely destroyed and the eschar falls off after 3-4 weeks, the wound surface repair depends on the skin grafting or the healthy skin growth of the epithelium from the wound edge. After healing, scars are formed and deformity is often caused.
The therapeutic effect judgment standard is as follows:
at present, the clinical symptoms and physical recovery conditions are mainly determined in various places.
The epidermis has no rot, blister, erythema, bleeding point, edema and pain, the basic symptoms disappear, and most functions are recovered to be normal. The wound surface is recovered to be normal in a short time, and the symptom accompanied with the organ tube damage in clinic basically disappears so as to completely recover.
The implementation examples show that:
1. wang somebody, male, 52 years old, businessman. Hand burn. The medicine is applied for 2-5 days without red and swollen blisters. The epidermis recovered naturally after 15 days.
2. Lie a certain, female, age 40, worker. The legs were scalded. Applying the ointment for 3-6 days, and soaking in water. The epidermis grew naturally after 10 days.
3. One certain, male, 30 years old, shop assistant. Face burn. After the ointment is applied for 7 days, the face has no pain sense. The cortical crust fell off after 13 days.
4. Liu somewhere, Man, 32 years old, chef. Hand burn with blisters. After the ointment is applied for 5 days, the water is soaked for natural decrustation. The new meat and cutin naturally recover in 10 days.
5. Old a certain woman, 20 years old, student. Scald of hands and feet, and local cortex exfoliation. The ointment is applied for 6 days, and no white spot or blood appears on hands and feet. After 13 days, the hand and foot keratinous tissues were self-healed.
6. Liu somewhere, man, 27 years old, handling worker. Leg scald and ulcerated meat. The powder is applied for 5 days without surface ulceration. After 12 days, no surface ulceration was observed.
7. Xin Yi, woman, 16 years old, student. Scald of face with red and swollen. The ointment is applied for 4 days without red swelling and inflammation. After 11 days, the wound surface was substantially normal.
8. Yang Yi in a certain age, male, 10 years old, children. Scald hands with slight blisters. The water bubble disappears after applying the ointment for 4 days. After 10 days, the surface of the wound of the epidermis is completely recovered.
The treatment results are as follows:
the number of patients with burn is 40 after clinical diagnosis and treatment. 30 men and 10 women. All the patients in 40 cases are cured without scars, and the patients have no adverse reaction and no damage symptom to organ tubes and are completely recovered.

Claims (5)

1. A traditional Chinese medicine composition for treating burn tissue scar is characterized by comprising, by weight, 5-40 parts of cinnabar, 15-45 parts of borneol, 40-80 parts of gypsum, 5-20 parts of pyrolusite, 5-15 parts of indigo naturalis and 5-25 parts of jade scraps.
2. The traditional Chinese medicine composition for treating the scar of the burned tissue as claimed in claim 1, which is characterized by consisting of, by weight, 20-30 parts of cinnabar, 20-40 parts of borneol, 50-70 parts of gypsum, 10-15 parts of pyrolusite, 10-15 parts of indigo naturalis and 10-20 parts of jade scraps.
3. The traditional Chinese medicine composition for treating the scar of the burned tissue as claimed in claim 1, which is characterized in that the traditional Chinese medicine composition for treating the scar of the burned tissue consists of 25 parts by weight of cinnabar, 30 parts by weight of borneol, 60 parts by weight of gypsum, 10 parts by weight of pyrolusite, 10 parts by weight of natural indigo and 15 parts by weight of jade scraps.
4. The traditional Chinese medicine composition for treating burn tissue scars according to claim 1, wherein the traditional Chinese medicine composition for treating burn tissue scars is prepared into powder.
5. The traditional Chinese medicine composition for treating burn tissue scars according to claim 4, wherein the traditional Chinese medicine composition for treating burn tissue scars is prepared into an ointment.
CN202110644400.6A 2021-06-09 2021-06-09 Traditional Chinese medicine composition for treating burn tissue scar Withdrawn CN113209167A (en)

Priority Applications (1)

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CN202110644400.6A CN113209167A (en) 2021-06-09 2021-06-09 Traditional Chinese medicine composition for treating burn tissue scar

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Application Number Priority Date Filing Date Title
CN202110644400.6A CN113209167A (en) 2021-06-09 2021-06-09 Traditional Chinese medicine composition for treating burn tissue scar

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Application publication date: 20210806