CN109432258A - A kind of Chinese medicine composition that treating burn and scald, preparation method and application - Google Patents
A kind of Chinese medicine composition that treating burn and scald, preparation method and application Download PDFInfo
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- CN109432258A CN109432258A CN201910022789.3A CN201910022789A CN109432258A CN 109432258 A CN109432258 A CN 109432258A CN 201910022789 A CN201910022789 A CN 201910022789A CN 109432258 A CN109432258 A CN 109432258A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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Abstract
The present invention relates to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicine composition for treating burn and scald, its preparation the method for the present invention and application.The composition is made by catechu, dragon's blood, rheum officinale, calcined gypsum and badger seed oil.The present invention is according to drug matching theory, selecting catechu, dragon's blood, rheum officinale, calcined gypsum and badger seed oil is raw material, pass through the reasonable compatibility between each component, Chinese medicine composition obtained is 83.3%~98.3% to the cure rate of burn and scald, and wound healing is fast, pain disappears fastly, pain can completely disappear within 10 minutes or so；Preventing from scar has reached optimum therapeuticing effect rapid-action, significant in efficacy without the special cleaning surface of a wound with less type.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of Chinese medicine compositions for treating burn and scald, preparation method
And application.
Background technique
Burn generally comprises hydrothermal solution (water, soup, oil etc.), steam, high-temperature gas, flame, red-hot metal liquid or solid (such as
Molten steel, steel ingot) etc. caused by histologic lesion, be primarily referred to as skin and/or mucous membrane, serious person can also injure it is subcutaneous or/and or
Sub-mucosal tissues, such as muscle, bone, joint even internal organ.Clinically also have and is referred to as the damage of heating power caused by hydrothermal solution, steam (burning) wound
For scald.The grading method of burn is more, and internationally used at present is three degree of quarterings, i.e., I degree, light degree Ⅱ, II degree of depth and
III degree.I degree of burn: also known as erythematous burn only injures a part of epidermis, but germinal layer is alive, thus proliferation regeneration ability
Active, Chang Yu heals in 3~5 days, does not stay scar.Superficial bums: entire epidermis and part papillaris pars are injured, due to germinal layer
Be partially damaged, the regeneration of epithelium depends on the germinal layer and the appendages of skin of remaining, such as the epitheliosis of sweat gland and hair follicle, such as without after
Hair infection, generally healed through 1~2 week or so, does not also stay scar.Deepⅱdegreeburn: burn depth and papillary layer of corium hereinafter, but still
Residual fraction corium and the appendages of skin, healing is dependent on the epidermis progenitor cells in appendages of skin epithelium, especially hair follicle protruding portion
Proliferation generally need 3~4 weeks self-heals, Chang Liuyou scar such as without infection.III degree of burn: also known as eschar burn, generally
Refer to the burn of whole skin, epidermis, corium and the appendages of skin are all damaged, and wound repair is repaired dependent on surgery skin grafting or flap
It is multiple.
Cause burn and scald most commonly to be scalded by boiled water or hot steam in daily life, many places in I degree, light degree Ⅱ,
Deep II degree of burn and scald, but many people often lack in common sense, and are treated with soy sauce, sesame oil, toothpaste, these indigenous methods of gentian violet, such as
Fruit burn and scald situation is more serious, can miss best occasion for the treatment using these methods, and scar is easy after treatment, can also be made
At psychological shade.
Currently, the traditional Chinese and western medicine external drug type of burn and scald is sweet more, wherein Chinese medicine preparation multicomponent is complicated, and it is slow to work.
Although the treatment effect of Western medicine is obvious, side effect is also very much, and is easy to produce pharmacological dependence.Therefore, existing treatment, which is burnt, scalds
The Chinese and western drugs of wound are unable to satisfy the needs of many patients, provide the treatment burn that a kind of component is few, quick, safety is good and scald
The drug of wound is of great significance.
Summary of the invention
In view of this, the purpose of the present invention is to provide a kind of Chinese medicine compositions for treating empyrosis, preparation method
And application.Chinese medicine composition provided by the invention is rapid-action to burn and scald, significant in efficacy, and safety is without side-effects.
The present invention provides a kind of Chinese medicine compositions for treating burn and scald, are made by following raw material: catechu, dragon's blood, rheum officinale,
Calcined gypsum and badger seed oil.
Wherein, catechu: promoting blood circulation and stopping pain, hemostasia and promoting granulation, hygroscopic sore, clearing lung and eliminating phlegm.Dragon's blood: promoting blood circulation analgesic therapy, removing blood stasis and hemostasis,
Expelling pus and promoting granulation.Rheum officinale: stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, removing toxic substances and other effects are attacked.Calcined gypsum, expelling pus and promoting granulation, hygroscopic, only
Blood.Badger seed oil: clearing heat and detoxicating, swelling and pain relieving.That closes gathers swelling and pain relieving altogether, the function removed the rotten and let fresh grow.
The present invention is according to drug matching theory, and selecting catechu, dragon's blood, rheum officinale, calcined gypsum and badger seed oil is raw material, by each
Reasonable compatibility between component, Chinese medicine composition obtained is rapid-action to burn and scald, significant in efficacy, can thoroughly eradicate I degree, shallow II
Degree, deep II degree of burn and scald, do not stay any scar.Daily dressing is primary, and less serious case 1~2 time is i.e. more, and severe one 3~5 times, rear injury
Without scar.
Composition provided by the invention is with natural Chinese medicinal herb (catechu, dragon's blood, rheum officinale), natural calcined gypsum and animal tallow oil
(badger seed oil) is made.In thousands of patients of application the traditional chinese medicine composition of the invention, allergic phenomena is found no, to the liver of patient
For renal function without influence, safety is without side-effects.
In some embodiments, each material quality number in the Chinese medicine composition are as follows: 35~50 parts of catechu, dragon's blood 25
~55 parts, 40~60 parts of rheum officinale, 25~50 parts of calcined gypsum and 35~65 parts of badger seed oil.In certain embodiments, in described
Each material quality number in drug composition are as follows: 50 parts of catechu, 50 parts of dragon's blood, 50 parts of rheum officinale, 50 parts of calcined gypsum and 50 parts of badger seed oil.
In certain embodiments, each material quality number in the Chinese medicine composition are as follows: 35 parts of catechu, 55 parts of dragon's blood, rheum officinale 40
Part, 35 parts of calcined gypsum and 65 parts of badger seed oil.In certain embodiments, each material quality number in the Chinese medicine composition
Are as follows: 40 parts of catechu, 25 parts of dragon's blood, 60 parts of rheum officinale, 25 parts of calcined gypsum and 35 parts of badger seed oil.
The present invention also provides the preparation methods of the Chinese medicine composition, catechu, dragon's blood, rheum officinale and calcined gypsum are crushed,
After sieving, badger seed oil is added, stirs evenly and obtains the Chinese medicine composition.
Wherein, catechu, dragon's blood, rheum officinale and calcined gypsum are smashed it through to the sieve of 100~150 mesh, preferably 100 mesh or
The sieve of 140 mesh.
The present invention also provides application of the above-mentioned Chinese medicine composition in preparation treatment burn, the drug scalded.
Meanwhile the present invention also provides a kind of paste for treating burn and scald, by any one of a effective amount of claims 1 to 3 institute
State Chinese medicine composition and pharmaceutically acceptable auxiliary material composition.
The Chinese medicine composition for the treatment of burn and scald provided by the invention is by catechu, dragon's blood, rheum officinale, calcined gypsum and badger seed oil system
?.The Chinese medicine composition is quick to burn and scald, significant in efficacy, can thoroughly eradicate to I degree, light degree Ⅱ, deep II degree of burn and scald, no
Stay any scar.Specifically, the present composition has the advantage that
1, there is significant analgesic efficacy, analgesic effect can be played after burn early stage surface of a wound application, 10 minutes or so, pain was complete
It totally disappeared mistake.
2, there is preferable convergence function, can protect the surface of a wound, reduce surface of a wound exudation.
3, clearing heat and detoxicating promoting muscle growth functions.The effect of removing necrosis and promoting granulation, after medication couple of days, the skin of damage will fall off,
The surface of a wound need not deliberately be cleared up.Promoting muscle growth functions can promote the growth and development of organic Skin Cell, using the traditional chinese medicine composition of the invention
After can shorten wound healing time.
4, have the function of that the surface of a wound is isolated from the outside, it is provided by the invention treatment burn and scald paste because ointment density compared with
Height can prevent the intrusion of bacterium after surface of a wound external-use ointment to a certain extent, can be played using exposure and half exposure treatment good
Therapeutic effect.
5, have the function of mitigating surface of a wound scar.Work with fibrocyte and epithelial cell ratio in adjustment skin histology
With, make restore epithelium close to normal organization, can reduce scar proliferation.It will not be stayed for being no more than deep II degree of burn and scald
Lower scar.
6, accelerate wound healing.It can provide histocyte regenerated moist environment, transfer the potential of regeneration, add
The physiological of the fast surface of a wound heals.
7, in thousands of patients of application the traditional chinese medicine composition of the invention, allergic phenomena is found no, to the liver kidney of patient
For function without influence, safety is without side-effects.
8, easy to use, it can be according to surface of a wound different parts and different condition, using users such as exposure, half exposure and wrappings
Method.
Specific embodiment
The invention discloses a kind of Chinese medicine composition for treating burn, its preparation the method for the present invention and application, this field skills
Art personnel can use for reference present disclosure, be suitably modified realization of process parameters.In particular, it should be pointed out that all similar replacements and
Change apparent to those skilled in the art, they are considered as being included in the present invention.Method of the invention and
Using being described by preferred embodiment, related personnel can obviously not depart from the content of present invention, spirit and scope
It is interior that method described herein and application are modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
To the explanation of the disclosed embodiments, enable those skilled in the art to implement or use the present invention.To this
A variety of modifications of a little embodiments will be readily apparent to those skilled in the art, as defined herein general
Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, the present invention will not
It can be intended to be limited to the embodiments shown herein, and be to fit to consistent with the principles and novel features disclosed in this article
Widest scope.
Below with reference to embodiment, the present invention is further explained:
The Chinese medicine composition of 1 present invention treatment burn and scald of embodiment
Each material quality number are as follows: 50 parts of catechu, 50 parts of dragon's blood, 50 parts of rheum officinale, 50 parts of calcined gypsum and 50 parts of badger seed oil.
Preparation method: after catechu, dragon's blood, rheum officinale and calcined gypsum are crushed, cross 140 meshes, badger seed oil is added, stirring is equal
It is even, obtain the Chinese medicine composition.
Embodiment 2
Each material quality number are as follows: 35 parts of catechu, 55 parts of dragon's blood, 40 parts of rheum officinale, 35 parts of calcined gypsum and 65 parts of badger seed oil.
Preparation method: after catechu, dragon's blood, rheum officinale and calcined gypsum are crushed, cross 140 meshes, badger seed oil is added, stirring is equal
It is even, obtain the Chinese medicine composition.
Embodiment 3
Each material quality number are as follows: 40 parts of catechu, 25 parts of dragon's blood, 60 parts of rheum officinale, 25 parts of calcined gypsum and 35 parts of badger seed oil.
Preparation method: after catechu, dragon's blood, rheum officinale and calcined gypsum are crushed, sieved with 100 mesh sieve, badger seed oil is added, stirring is equal
It is even, obtain the Chinese medicine composition.
Comparative example 1
In the comparative example, each group distribution ratio is different from the present invention each material quality number are as follows: 60 parts of catechu, 40 parts of dragon's blood,
30 parts of rheum officinale, 30 parts of calcined gypsum and 40 parts of badger seed oil.
Preparation method: after catechu, dragon's blood, rheum officinale and calcined gypsum are crushed, cross 140 meshes, badger seed oil is added, stirring is equal
It is even, obtain the Chinese medicine composition.
Comparative example 2
Each material quality number are as follows: 50 parts of catechu, 50 parts of dragon's blood, 50 parts of rheum officinale, 50 parts of calcined gypsum and 50 parts of peanut oil.
Preparation method: after catechu, dragon's blood, rheum officinale and calcined gypsum are crushed, cross 120 meshes, peanut oil is added, stirring is equal
It is even, obtain the Chinese medicine composition.
4 clinical effect trial of embodiment
Burn patient 600 are selected, wherein mild burn, moderate burn and each 200 people of severe burn, the burning of same rank
Hurt degree and Burn situation be more close, be equally divided into 5 groups, every group of 120 people, i.e., every group include 40 mild burn patients,
40 moderate burn patients and 40 mild burn patients.Every group is made using 1~3 Chinese medicine composition of the embodiment of the present invention respectively
Burn cream, burn cream made of 1~2 Chinese medicine composition of comparative example, treatment results are shown in Table 1.
Curative effect criterion of cure: wound healing, preventing from scar or scar are extremely shallowly not easy to find out.
1 treatment results of table
Embodiment 5 cures case introduction
1, male, 8 years old, thermos bottle is kicked accidentally broken when being at play, leads to right crus of diaphragm large-area burns, many places get blister, peel,
In great pain, pain disappears immediately after ointment made of smearing 1 Chinese medicine composition of the embodiment of the present invention, bubble reduces after one day,
It is cured after continuous medication for five days, burn site does not stay scar.
2, female, 11 years old, male 10 years old, knocked the thermos bottle on nightstand over (broken) sisters play together when, leads to male
Child shirtfront girl's back part scald, many places get blister, are in great pain, smear medicine made of 2 Chinese medicine composition of the embodiment of the present invention
Cream, pain disappear, cure after continuous medication for five days, do not stay scar.
3, female 36 years old, in cooking, is hurt by rusting (splashing), and neck and shirtfront many places rubefaction, swelling feel fire
Peppery ground pain, but appearance without blister, smear ointment made of 3 Chinese medicine composition of the embodiment of the present invention, morning swelling disappears
It loses, fully recovers within three days.
4, female, 50 years old, scalding both legs were most of, and a large amount of bubbles are in great pain.It smears in the embodiment of the present invention 1
Ointment made of drug composition, bubble Lock-out, slowly blackening, exsiccation fall off naturally, fully recover within seven days.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating burn and scald, which is characterized in that be made by following raw material: catechu, rheum officinale, is forged dragon's blood
Gypsum and badger seed oil.
2. Chinese medicine composition according to claim 1, which is characterized in that each material quality number are as follows: 35~50 parts of catechu, blood
Exhaust 25~55 parts, 40~60 parts of rheum officinale, 25~50 parts of calcined gypsum and 35~65 parts of badger seed oil.
3. Chinese medicine composition according to claim 2, which is characterized in that each material quality number are as follows: 50 parts of catechu, dragon's blood 50
Part, 50 parts of rheum officinale, 50 parts of calcined gypsum and 50 parts of badger seed oil.
4. the preparation method of any one of claims 1 to 3 Chinese medicine composition, which is characterized in that by catechu, dragon's blood, rheum officinale
It is crushed with calcined gypsum, after sieving, badger seed oil is added, stirred evenly and obtain the Chinese medicine composition.
5. preparation method according to claim 4, which is characterized in that the sieving was the sieve of 100~150 mesh.
6. application of any one of claims 1 to 3 Chinese medicine composition in preparation treatment burn, the drug scalded.
7. a kind of paste for treating burn and scald, which is characterized in that by any one of a effective amount of claims 1 to 3 Chinese medicine group
Close object and pharmaceutically acceptable auxiliary material composition.
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| CN201910022789.3A CN109432258A (en) | 2019-01-10 | 2019-01-10 | A kind of Chinese medicine composition that treating burn and scald, preparation method and application |
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| CN201910022789.3A CN109432258A (en) | 2019-01-10 | 2019-01-10 | A kind of Chinese medicine composition that treating burn and scald, preparation method and application |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079395A (en) * | 1993-03-06 | 1993-12-15 | 杜彦如 | Scald medicine |
| CN1085436A (en) * | 1992-10-05 | 1994-04-20 | 王春华 | The manufacture method of burn-scald medicine |
| CN102961543A (en) * | 2011-08-29 | 2013-03-13 | 牛俊岭 | Method for preparing muscle-growing oil |
| CN107362207A (en) * | 2016-10-25 | 2017-11-21 | 刘树祯 | A kind of medicament for treating scald |
-
2019
- 2019-01-10 CN CN201910022789.3A patent/CN109432258A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085436A (en) * | 1992-10-05 | 1994-04-20 | 王春华 | The manufacture method of burn-scald medicine |
| CN1079395A (en) * | 1993-03-06 | 1993-12-15 | 杜彦如 | Scald medicine |
| CN102961543A (en) * | 2011-08-29 | 2013-03-13 | 牛俊岭 | Method for preparing muscle-growing oil |
| CN107362207A (en) * | 2016-10-25 | 2017-11-21 | 刘树祯 | A kind of medicament for treating scald |
Non-Patent Citations (1)
| Title |
|---|
| 刘淑云等: "《满族医药》", 30 June 2014, 中医古籍出版社 * |
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Application publication date: 20190308 |