CN108339184A - A kind of anesthesia dressing packet and preparation method thereof for skin surface - Google Patents
A kind of anesthesia dressing packet and preparation method thereof for skin surface Download PDFInfo
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- CN108339184A CN108339184A CN201810144038.4A CN201810144038A CN108339184A CN 108339184 A CN108339184 A CN 108339184A CN 201810144038 A CN201810144038 A CN 201810144038A CN 108339184 A CN108339184 A CN 108339184A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M19/00—Local anaesthesia; Hypothermia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A61K35/63—Arthropods
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- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M35/00—Devices for applying media, e.g. remedies, on the human body
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The anesthesia dressing packet and preparation method thereof that the invention discloses a kind of for skin surface, it is related to arcotic technical field, it includes coating, sponge gourd network layers, basal layer to anaesthetize dressing packet, the sponge gourd network layers are the luffa filled with anesthetic, the anesthetic accounts for the 10 60% of sponge gourd network layers gross mass, the luffa be impregnated successively through water, Peracetic acid and cross chloric acid impregnate, the loofah fiber of Esterification modification, raw material prepared by the basal layer include alum particle, the dandelion of drying, drying purslane.Can also anti-inflammation and sterilization the object of the present invention is to provide the anesthesia packet for skin epidermis, while can keeping anesthesia drug effect, moreover it is possible to ensure easy to use, removal, and by anesthetic ointment it is fully wrapped around including, be not easy to ooze out.
Description
Technical field
The present invention relates to arcotic technical fields more particularly to a kind of for the anesthesia dressing packet of skin surface and its preparation
Method.
Background technology
Local anesthetic refers to that those energy within the scope of the restriction of human body are temporary, completely, reversibly block nerves are conducted, i.e.,
So that certain part of human body is lost sensibility under the situation that consciousness does not disappear, in order to the drug that surgical operation carries out, but injects
Local anesthetic will produce pain, and patient is not easily accepted by, therefore the appearance of surface anaesthetic, largely eliminate patient
To the feared state of mind of injecting anesthetic, reduce stimulation and damage of the injecting anesthetic to patient part, it is desirable to enhance matching for patient
Know, contribute to treatment be smoothed out and the early recovery of patient；In life, at skin injury or other are needed temporarily only
The position of pain is not suitable for direct injection anesthesia yet.So surface anesthesia is clinically, the application range between different department
It is increasingly wider, for example, for pediatric patient, played using surface anesthesia to stablizing the mood of children, enhancing its cooperative
Effect well, for beautifying skin section, when beautifying face laser therapy, need not carry out deep anaesthesia, it is only necessary to by skin
Skin epidermis is anaesthetized.
Current surface anesthesia is applied to affected part using with anesthetic ointment mostly, but in use, some
When needing surface anesthesia by the position that clothing covers in, anesthetic ointment will be accidentally infected on clothing, Huo Zheer
Child, which waits for accidentally eating in anaesthesia process after smearing, can cause certain danger, and accidentally wiping can cause anaesthetic effect to subtract
It is weak.Anesthetic ointment is combined wrapping with dressing, sticks on affected part, the above problem is also avoided while playing local anesthetic action,
But traditional dressing can make the reduction of anesthesia drug effect after simply being combined with arcotic.Therefore the present invention provides one kind being used for skin
The anesthesia dressing on surface, while keeping anaesthetizing drug effect can also anti-inflammation and sterilization, easy to use, cleaning, and by anesthetic ointment
It is completely encapsulated in dressing, is not easy to ooze out.
Invention content
In view of this, the anesthesia dressing packet and preparation method thereof that the object of the present invention is to provide a kind of for skin surface,
Anaesthetize dressing packet be used for skin epidermis anesthesia, keep anaesthetize drug effect while can also anti-inflammation and sterilization, it is easy to use, cleaning,
And anesthetic ointment is completely encapsulated in dressing, is not easy to ooze out.
The present invention solves above-mentioned technical problem by following technological means：
A kind of anesthesia dressing packet for skin surface, including coating, sponge gourd network layers, basal layer, the sponge gourd network layers
For the luffa filled with anesthetic, the anesthetic accounts for the 10-60% of sponge gourd network layers gross mass, and the luffa is to pass through successively
Water immersion, Peracetic acid and the loofah fiber for crossing chloric acid immersion, Esterification modification, raw material prepared by the basal layer
Including alum particle, the dandelion of drying, drying purslane.
Luffa is a kind of natural degradable and the sustainable regenerated natural vascular bundle group for possessing cellulosic reticular structure
It knits also known as sponge gourd sponge, plant sponge, light and pore structure is flourishing, and tensile ductility is good.When anesthetic is filled in inside
In use, anesthetic can be not only adsorbed on inside luffa by luffa, its good ductility is utilized when can also stretch, it will
Anesthetic squeezes out, and is used for anesthesia.Contain polyphenol oxidase in water, have oxidation susceptibility, by water with
Ethanol solution is mixed, and can avoid growing bacterium.There are amorphous regions in the macromolecular of loofah fiber, are soaked with water
After bubble processing, loofah fiber, which is aoxidized, there is shrinkage phenomenon, while becoming more flexible.By follow-up a series of behaviour
After work, when for filling anaesthetic, the overall structure of anaesthetic will not be destroyed.
Further, the coating is scalable oolemma, and there are two adhesive tapes in both sides respectively.
Both sides adhesive tape is stretched when use and expands its usable floor area using the ductility of luffa, to be completely covered on
Affected part.Adhesive tape is viscous on the skin for fixed anesthesia dressing packet, its landing is avoided, adhesive tape is torn after use, takes
Walk to anaesthetize dressing packet.
Further, the sponge gourd network layers be filled with anesthetic, the anesthetic be include external narcotic, transdermal promotion
Agent, broad-spectrum bactericidal effect agent, antioxidant.Anesthesia sterilization component of the broad-spectrum bactericidal effect agent as anesthesia dressing packet.
Further, the preparation of the anesthesia dressing packet includes the following steps：Sponge gourd network layers are soaked with water vapour, and to prolong
Exhibition state is immersed in 2-3min in anesthetic, it is then made to be retracted to original state, repeat to extend, collapse step three times after, take out in
25-40 DEG C of drying in oven；Luffa is immersed in anesthetic, repeatedly extends, shrinkage operation, more anesthetic can be soaked
Enter inside luffa.
Further, laminated by coating viscose and cover surface adherency in luffa；Luffa be can avoid from anesthesia
The agent other end squeezes out.
The purslane of alum particle, the dandelion of drying, drying is crushed into powder and is mixed with clear water, paste is stirred into, adds
Heat, filtering, obtained filter residue are uniformly applied to the another side of sponge gourd network layers, are dried to obtain basal layer, the smearing of the basal layer
Thickness be 1-3mm to get to anesthesia dressing packet.There is alum antibacterial astriction, dandelion there is clearing heat and detoxicating, beauty to support
The effect of face, dispersing swelling and dissipating binds, antibacterial, purslane also have the function of bactericidal antiphlogistic, blood pressure lowering, anti-aging, are used as very thin
Basal layer has the function of that detoxicating, killing bacteria, antipyretic and itching-stopping, swelling and pain relieving, promoting granulation and wound healing, Cooperation Anaesthesia medicine are used together using effect
Fruit is more preferably.
Further, the preparation method of the sponge gourd network layers includes the following steps：
1. luffa pre-processes：Take 100-200 portions of luffas to be cleaned, air-dry after, be put into 100-300ml waters
In 20-50ml absolute ethyl alcohol mixed solutions, in 20-30 DEG C of immersion 12-24h of temperature, take out, deionized water is cleaned, and 30- is put into
It is dried in 60 DEG C of baking oven, obtains loofah fiber；It, can be to luffa table after luffa impregnates in Weak alkali plant juice
Face can carry out mercerization, can inhibit the growth of bacterium after addition ethyl alcohol at low ambient temperatures.
Dry loofah fiber is soaked in crossed containing 5-15wt% Peracetic acid, 0.05-1wt% chloric acid mixing it is molten
In liquid, 40-60min is stirred in water bath with thermostatic control, obtains pretreated luffa；
2. luffa is esterified：It configures 30-80wt% glacial acetic acid, 20-70wt% acetic anhydride to mixed solution, is cooled to 5-
8 DEG C, concentrated sulfuric acid 15-25ml is added, is added after pretreated luffa is stirred to react 1-2h and takes out in 10-15 DEG C, place
It is added after 5-10min in the sodium bicarbonate solution of a concentration of 15-40wt%, in 30-60 DEG C of drying in oven, deionized water is anti-
Multiple cleaning, air-dries, the luffa after being esterified；Its elasticity can be more preferable after luffa is esterified, and also increases luffa
Resistance to acid and alkali and organic solvent resistance, by arcotic filling enter after luffa will not be corroded.
3. the preparation of sponge gourd network layers：Take 10-20 parts of water soluble chitosans, 10-15 parts of propolis, 2-5 parts of gelatin mixing, stirring
It is added in the acetum of 2-5wt% until being completely dissolved, addition 2-5ml glycerine mixings add the acetone soln of 1-3wt%
Mixing is poured into bottle,suction, and 20-30min is filtered by vacuum under 1-3Mpa, obtains filtrate, and the luffa after esterification is immersed filter
10-20min is impregnated in liquid, is taken out, is dried, obtain sponge gourd network layers, be put into drier and preserve.Chitosan acts not only as resisting
The material of bacterium anti-inflammatory, is also used as antioxidant, avoids the oxidation deterioration of arcotic；There is propolis moisturizing myogenic, anti-inflammatory to stop
The effect of pain, can also be with the activity of raising drug, and increase drug effect, glycerine and acid are happened at after reacting in system, to silk
Melon network plays the role of further toughening, avoids that in use, luffa being torn.
Further, the basicity of the water is more than 7, and the water is balsam pear juice, Brussels sprouts juice, the volume heart
Vegetable juice liquid, spinach juice, cucumber juice, green pepper juice, carrot juice any of which or a variety of mixing.The plant
Juice is in alkalescent, can be by luffa surface mercerization.
Beneficial effects of the present invention：
The anesthesia dressing packet that the present invention designs is used for the anesthesia of skin epidermis, can also anti-inflammatory while keeping anaesthetizing drug effect
Sterilization, easy to use, cleaning, and by inside the fully wrapped around luffa of anesthetic ointment, be not easy to ooze out, in use, pullling both ends
Anesthetic inside luffa is squeezed out, sticks on affected part by adhesive tape, skin surface can be made to anaesthetize.
Description of the drawings
Fig. 1 is the structural schematic diagram of the present invention；
Fig. 2 is the unfolded state structural schematic diagram of the present invention；
Wherein, adhesive tape 1, coating 2, sponge gourd network layers 3, anesthetic 4, basal layer 5.
Specific implementation mode
Below with reference to the drawings and specific embodiments, the present invention is described in detail：
As depicted in figs. 1 and 2, a kind of anesthesia dressing packet for skin surface, including coating 2, sponge gourd network layers 3, base
Bottom 5,3 inside of sponge gourd network layers are filled with anesthetic 4；Basal layer 5 include alum particle, the dandelion of drying, drying dent
The paste that amaranth is mixed；Coating 2 is scalable oolemma, and there are two adhesive tapes 1 in both sides respectively；Deionization when use
Water spray soaks basal layer 5, stretches the adhesive tape 1 of both sides respectively, affected part is pasted onto after dressing packet reaches largest deformation.
Embodiment one：The preparation one of sponge gourd network layers 3
1. 100 parts by weight luffa of raw material is cleaned, air-dry after be put into the filtered carrot juice of 100ml and
In 20ml absolute ethyl alcohol mixed solutions, in 20 DEG C of immersion 12h of temperature, take out, deionized water is cleaned, and is put into 30 DEG C of baking oven and is dried
It is dry, obtain loofah fiber；
Dry loofah fiber is soaked in and crosses chloric acid containing 10ml 5wt% Peracetic acid, 10ml 0.05wt% and mixes
It closes in solution, 40min is stirred in water bath with thermostatic control, obtains pretreated luffa；
2. configuring 100ml 30wt% glacial acetic acid, 100ml 20wt% acetic anhydride to mixed solution, it is cooled to 5 DEG C, then
Concentrated sulfuric acid 15ml is added, makes reaction temperature control at 10-15 DEG C or so, pretreated luffa is added by several times, is constantly stirred
Mix, react 60min after take out, place 5min after be added 20ml 15wt% sodium bicarbonate solutions in and residual acid, in 30 DEG C of baking
Drying, is cleaned after drying with deionized water repeatedly in case, is air-dried, the luffa after being esterified；
3. 10 parts by weight water-soluble chitosans, 10 parts by weight propolis, 2 parts by weight gelatin are mixed, it is molten that 2wt% acetic acid is added
Until being completely dissolved, addition 2ml glycerine uniformly adds the acetone soln of 8ml 1wt%, stirs evenly, pour into bottle,suction liquid
In, it is taken out after 20min is filtered by vacuum at 1Mpa, obtains filtrate, the luffa after esterification is immersed in filtrate and impregnates 10min
Afterwards, it takes out, dries, be put into drier and preserve, obtain sponge gourd network layers 3.
Embodiment two：The preparation two of sponge gourd network layers 3
1. being put into the filtered cabbages of 200ml and wild cabbage after 150 parts by weight luffa of raw material is cleaned, is air-dried
In the mixing juice and 35ml absolute ethyl alcohol mixed solutions of dish, in 25 DEG C of immersion 20h of temperature, take out, deionized water is cleaned, and is put into
It is dried in 50 DEG C of baking oven, obtains loofah fiber；
Dry loofah fiber is dipped in and crosses chloric acid mixing containing 15ml 13wt% Peracetic acid, 15ml 0.07wt%
In solution, 50min is stirred in water bath with thermostatic control, obtains pretreated luffa；
2. configuring 120ml 60wt% glacial acetic acid, 120ml 50wt% acetic anhydride to mixed solution, it is cooled to 6 DEG C, then
Concentrated sulfuric acid 20ml is added, makes reaction temperature control at 10-15 DEG C or so, pretreated luffa is added by several times, is constantly stirred
Mix, react 100min after take out, place 8min after be added 25ml 25wt% sodium bicarbonate solutions in and residual acid, in 50 DEG C of baking
Drying, is cleaned after drying with deionized water repeatedly in case, is air-dried, the luffa after being esterified；
3. 16 parts by weight water-soluble chitosans, 13 parts by weight propolis, 3 parts by weight gelatin are mixed, it is molten that 3wt% acetic acid is added
Until being completely dissolved, addition 4ml glycerine uniformly adds the acetone soln of 10ml 2wt%, stirs evenly liquid, pours into suction filtration
It in bottle, is taken out after 25min is filtered by vacuum at 1.5Mpa, obtains filtrate, the luffa after esterification is immersed in filtrate and is impregnated
After 15min, takes out, dry, be put into drier and preserve, obtain sponge gourd network layers 3.
Embodiment three：The preparation three of sponge gourd network layers 3
1. being put into Bitter Melon Juice and 50ml water after 300ml filterings after 200 parts by weight luffa of raw material is cleaned, is air-dried
In alcohol mixed solution, impregnates for 24 hours for 30 DEG C, take out, deionized water is cleaned, and is put into 60 DEG C of baking oven and is dried, obtains in temperature
Loofah fiber；
Dry loofah fiber is soaked in and crosses chloric acid mixing containing 20ml 15wt% Peracetic acid, 20ml 1wt%
In solution, 60min is stirred in water bath with thermostatic control, obtains pretreated luffa；
2. configuring 130ml 80wt% glacial acetic acid, 130ml 70wt% acetic anhydride to mixed solution, it is cooled to 8 DEG C, then
Concentrated sulfuric acid 25ml is added, makes reaction temperature control at 10-15 DEG C or so, pretreated luffa is added by several times, is constantly stirred
Mix, react 120min after take out, place 10min after be added 30ml 40wt% sodium bicarbonate solutions in and residual acid, at 30-60 DEG C
Drying in oven, cleaned repeatedly with deionized water after drying, air-dry, the luffa after being esterified；
3. 20 parts by weight water-soluble chitosans, 15 parts by weight propolis, 5 parts by weight gelatin are mixed, it is molten that 5wt% acetic acid is added
Until being completely dissolved, addition 5ml glycerine uniformly adds the acetone soln of 12ml 3wt%, stirs evenly liquid, pours into suction filtration
It in bottle, takes out, the luffa after esterification is immersed in filtered mixed solution, 20min after 30min is filtered by vacuum at 3Mpa
After take out, dry, be put into drier and preserve, obtain sponge gourd network layers 3.
Example IV：Anaesthetize the preparation one of dressing packet
Any one the sponge gourd network layers 3 prepared in embodiment one, embodiment two, embodiment three are soaked with water vapour, it will
Sponge gourd network layers 3 are immersed in arcotic 120 seconds with extended state, it is then made to be retracted to original state, repeat extension, collapse step three
After secondary, the drying in oven at 25 DEG C is taken out, anesthetic 4 is compounded in inside sponge gourd network layers 3；
In 3 top coating viscose of sponge gourd network layers and 2 surface adhesion of coating；
The purslane of alum particle, the dandelion of drying, drying is crushed into powder and is mixed with clear water, paste is stirred into, adds
Heat, filtering, obtained filter residue are uniformly applied to 3 another side of sponge gourd network layers, are dried to obtain basal layer 5, and the smearing of basal layer 5 is thick
Degree be 1mm to get to anesthesia dressing packet.
Embodiment five：Anaesthetize the preparation two of dressing packet
A kind of sponge gourd network layers arbitrarily prepared in embodiment one, embodiment two, embodiment three are soaked with water vapour, by silk
Melon network layers 3 are immersed in arcotic 160 seconds with extended state, it is then made to be retracted to original state, repeat extension, collapse step three times
Afterwards, the drying in oven at 30 DEG C is taken out, anesthetic 4 is compounded in inside sponge gourd network layers 3；
In 3 top coating viscose of sponge gourd network layers and 2 surface adhesion of coating；
The purslane of alum particle, the dandelion of drying, drying is crushed into powder and is mixed with clear water, paste is stirred into, adds
Heat, filtering, obtained filter residue are uniformly applied to 3 another side of sponge gourd network layers, are dried to obtain basal layer 5, and the smearing of basal layer 5 is thick
Degree be 2mm to get to anesthesia dressing packet.
Embodiment six：Anaesthetize the preparation three of dressing packet
A kind of sponge gourd network layers arbitrarily prepared in embodiment one, embodiment two, embodiment three are soaked with water vapour, by silk
Melon network layers 3 are immersed in arcotic 180 seconds with extended state, it is then made to be retracted to original state, repeat extension, collapse step three times
Afterwards, the drying in oven at 40 DEG C is taken out, anesthetic 4 is compounded in inside sponge gourd network layers 3；
In 3 top coating viscose of sponge gourd network layers and 2 surface adhesion of coating；
The purslane of alum particle, the dandelion of drying, drying is crushed into powder and is mixed with clear water, paste is stirred into, adds
Heat, filtering, obtained filter residue are uniformly applied to 3 another side of sponge gourd network layers, are dried to obtain basal layer 5, and the smearing of basal layer 5 is thick
Degree be 3mm to get to anesthesia dressing packet.
Embodiment seven：Anaesthetize the application method of dressing packet
Any one anesthesia dressing packet deionized water spraying profit prepared by embodiment five, embodiment six, embodiment seven
Then wet basis bottom 5 stretches the adhesive tape 1 of both sides, expands its usable floor area, be covered in affected part, adhesive tape 1 is sticked to skin respectively
On skin, it is used for fixed anesthesia dressing packet, adhesive tape 1 is torn after the completion of use.
The above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although with reference to preferred embodiment to this hair
It is bright to be described in detail, it will be understood by those of ordinary skill in the art that, it can modify to technical scheme of the present invention
Or equivalent replacement should all cover the claim in the present invention without departing from the objective and range of technical solution of the present invention
In range.Technology that the present invention is not described in detail, shape, construction part are known technology.
Claims (6)
1. a kind of anesthesia dressing packet for skin surface, which is characterized in that the anesthesia dressing packet includes coating, luffa
Layer, basal layer, the sponge gourd network layers are the luffa filled with anesthetic, and the anesthetic accounts for the 10- of sponge gourd network layers gross mass
60%, the luffa is successively through water immersion, Peracetic acid and the luffa fibre for crossing chloric acid immersion, Esterification modification
Dimension, the raw material of the basal layer include alum particle, the dandelion of drying, drying purslane.
2. a kind of anesthesia dressing packet for skin surface according to claim 1, which is characterized in that the coating is
Flexible oolemma, and both sides are connected separately with two adhesive tapes.
3. a kind of anesthesia dressing packet for skin surface according to claim 2, which is characterized in that the sponge gourd network layers
Filled with anesthetic, the anesthetic includes external narcotic, transdermal enhancer, broad-spectrum bactericidal effect agent and antioxidant.
4. a kind of preparation method of anesthesia dressing packet for skin surface according to claim 3, which is characterized in that institute
The preparation for stating anesthesia dressing packet includes the following steps：
Sponge gourd network layers are soaked with water vapour, and 2-3min in anesthetic is immersed in extended state, then it are made to be retracted to original
Shape takes out after repeating extension, collapse step three times in 25-40 DEG C of drying in oven；
It is laminated by coating viscose and cover surface adherency in luffa；
The purslane of alum particle, the dandelion of drying, drying is crushed into powder and is mixed with clear water, paste is stirred into, is heated, mistake
Filter, obtained filter residue are uniformly applied to the another side of sponge gourd network layers, are dried to obtain basal layer, and the smearing thickness of the basal layer is
1-3mm to get to anesthesia dressing packet.
5. a kind of preparation method of anesthesia dressing packet for skin surface according to claim 4, which is characterized in that institute
The preparation method for stating sponge gourd network layers includes the following steps：
1. luffa pre-processes：Take 100-200 portions of luffas to be cleaned, air-dry after, be put into 100-300ml waters and
In 20-50ml absolute ethyl alcohol mixed solutions, in 20-30 DEG C of immersion 12-24h of temperature, take out, deionized water is cleaned, and 30-60 is put into
DEG C baking oven in dry, obtain loofah fiber；
Loofah fiber is soaked in and is crossed in the mixed solution of chloric acid containing 5-15wt% Peracetic acid, 0.05-1wt%, constant temperature
Stirring in water bath 40-60min obtains pretreated luffa；
2. luffa is esterified：It configures 30-80wt% glacial acetic acid, 20-70wt% acetic anhydride to mixed solution, is cooled to 5-8 DEG C,
Concentrated sulfuric acid 15-25ml is added, is added after pretreated luffa is stirred to react 1-2h and takes out in 10-15 DEG C, place 5-
It is added after 10min in the sodium bicarbonate solution of a concentration of 15-40wt%, in 30-60 DEG C of drying in oven, deionized water is repeatedly
Cleaning air-dries, the luffa after being esterified；
3. the preparation of sponge gourd network layers：10-20 parts of water soluble chitosans, 10-15 parts of propolis, 2-5 parts of gelatin mixing, stirring are taken to be added
Until being completely dissolved in the acetum of 2-5wt%, 2-5ml glycerine mixings are added, the acetone soln for adding 1-3wt% is mixed
It is even, 20-30min is filtered by vacuum under 1-3Mpa, obtains filtrate, the luffa after esterification is immersed in filtrate and impregnates 10-
20min takes out, dries, obtain sponge gourd network layers, be put into drier and preserve.
6. a kind of preparation method of anesthesia dressing packet for skin surface according to claim 5, which is characterized in that institute
State water basicity be more than 7, the water be balsam pear juice, Brussels sprouts juice, cabbage juice, spinach juice,
Any one in cucumber juice, green pepper juice, carrot juice or a variety of mixing.
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| CN110124175A (en) * | 2019-06-04 | 2019-08-16 | 武汉圣润生物科技有限公司 | A kind of local operation anesthesia paster |
| CN113616626A (en) * | 2021-09-01 | 2021-11-09 | 湖南慧泽生物医药科技有限公司 | Medical application with anesthesia effect and application thereof |
| CN116077495A (en) * | 2023-02-10 | 2023-05-09 | 四川大学华西医院 | External anesthetic, preparation method thereof and auxiliary material containing same |
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| CN116077495B (en) * | 2023-02-10 | 2024-03-19 | 四川大学华西医院 | External anesthetic, preparation method thereof and auxiliary material containing same |
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