CN109865126A - Wound surface nurses ointment and preparation method thereof - Google Patents
Wound surface nurses ointment and preparation method thereof Download PDFInfo
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- CN109865126A CN109865126A CN201910144129.2A CN201910144129A CN109865126A CN 109865126 A CN109865126 A CN 109865126A CN 201910144129 A CN201910144129 A CN 201910144129A CN 109865126 A CN109865126 A CN 109865126A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 40
- 239000002674 ointment Substances 0.000 title claims abstract description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 56
- 235000004347 Perilla Nutrition 0.000 claims abstract description 54
- 239000000284 extract Substances 0.000 claims abstract description 53
- 239000000843 powder Substances 0.000 claims abstract description 48
- 241000208422 Rhododendron Species 0.000 claims abstract description 39
- 229940069521 aloe extract Drugs 0.000 claims abstract description 37
- 239000008213 purified water Substances 0.000 claims abstract description 22
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 20
- 230000000474 nursing effect Effects 0.000 claims abstract description 20
- 239000004909 Moisturizer Substances 0.000 claims abstract description 19
- 230000000740 bleeding effect Effects 0.000 claims abstract description 19
- 230000001333 moisturizer Effects 0.000 claims abstract description 19
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 17
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 17
- 102000009024 Epidermal Growth Factor Human genes 0.000 claims abstract description 13
- 101800003838 Epidermal growth factor Proteins 0.000 claims abstract description 13
- 229940116977 epidermal growth factor Drugs 0.000 claims abstract description 13
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- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 11
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 11
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 11
- 241000229722 Perilla <angiosperm> Species 0.000 claims description 53
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 39
- 238000003756 stirring Methods 0.000 claims description 32
- 239000007788 liquid Substances 0.000 claims description 21
- 241001116389 Aloe Species 0.000 claims description 17
- 235000011399 aloe vera Nutrition 0.000 claims description 17
- 238000002156 mixing Methods 0.000 claims description 15
- 239000007921 spray Substances 0.000 claims description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- 238000004140 cleaning Methods 0.000 claims description 7
- 238000010790 dilution Methods 0.000 claims description 7
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- 238000001914 filtration Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 239000010642 eucalyptus oil Substances 0.000 claims description 4
- 229940044949 eucalyptus oil Drugs 0.000 claims description 4
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 3
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims description 3
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 3
- 229940116229 borneol Drugs 0.000 claims description 3
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 3
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 3
- 229960003639 laurocapram Drugs 0.000 claims description 3
- 229940041616 menthol Drugs 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 2
- 241000544061 Cuculus canorus Species 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 244000223014 Syzygium aromaticum Species 0.000 claims 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims 1
- 230000008595 infiltration Effects 0.000 claims 1
- 238000001764 infiltration Methods 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 239000000341 volatile oil Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 4
- 230000035876 healing Effects 0.000 abstract description 4
- 230000007794 irritation Effects 0.000 abstract description 4
- 231100000241 scar Toxicity 0.000 abstract description 4
- 230000003796 beauty Effects 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 244000124853 Perilla frutescens Species 0.000 abstract 1
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- 206010052428 Wound Diseases 0.000 description 32
- 210000003491 skin Anatomy 0.000 description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 9
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- 229920002385 Sodium hyaluronate Polymers 0.000 description 2
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- 208000015181 infectious disease Diseases 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 229940010747 sodium hyaluronate Drugs 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010017711 Gangrene Diseases 0.000 description 1
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- 240000008042 Zea mays Species 0.000 description 1
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- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 125000002604 borneol group Chemical group 0.000 description 1
- 239000010634 clove oil Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
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Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of wound surface nursing ointment, each component including following parts by weight: 20-50 parts of perilla leaf extract, 15-40 parts of Folium Artemisiae Argyi extract, 10-30 parts of aloe extract, 10-40 parts of the root powder of azalea, 10-30 parts of epidermal growth factor, 20-60 parts of albolene, 30-60 parts of carboxymethyl cellulose, 20-40 parts of polyethylene glycol, 5-15 parts of moisturizer, 10-35 parts of bleeding agent, 80-150 parts of purified water.The present invention also provides a kind of preparation methods of wound surface nursing ointment.The beneficial effects of the present invention are: 1, of the present invention wound surface nurse ointment, and irritation is small, highly-safe, good effect, and after healing, skin surface not will form scar, not influence skin beauty；2, the preparation method of wound surface nursing ointment of the present invention, preparation process is simple, raw material sources are extensive, preparation cost is cheap, wide market.
Description
Technical field
The present invention relates to a kind of wound surface nursing ointment and preparation method thereof, belong to medical wound nursing technique field.
Background technique
In the busy modern life, human skin it is small to scratch, arrives operative incision, skin burn greatly, we without when without
Quarter does not come into contacts with the surface of a wound.Various wounds usually cause the damage of skin and soft tissue, even amputation when serious.Wound
Reason is correct, it can be made to heal rapidly, on the contrary, it is likely that meeting suppurative infection does not recover for a long time, or even can concurrent general infection, gas
The threat to life such as property gangrene, tetanus.
Traditional wound processing method: keeping wound open, promotes wound knot silly, wound is dry, but traditional processing
There is more disadvantages to break for method, such as: bioactive substance is lost, speed of wound healing is slow, patient pain, muptiple-use machine
Tool damage.For healing acceleration, people are in wound post-processing, generally by the way of smearing ointment, but existing wound
Processing ointment still has following disadvantage: antibacterial bacteriostatic effect is poor, irritation is big, safety is poor, curative effect is poor, treatment cycle
Length, speed of wound healing are slower, and certain inconvenience is caused to the wounded；And after curing, skin surface easily forms scar, influences skin
Skin is beautiful, is easy to cause certain injury to the psychology of the wounded.
Therefore, the present invention provides a kind of wound surface nursing ointment and preparation method thereof, and solves the above problems.
Summary of the invention
One of the technical problems to be solved by the present invention are: to solve above-mentioned technical problem, a kind of wound surface shield is provided
Ointment machin preparation method is managed, irritation existing for existing treatment of wounds ointment is big, safety is poor, curative effect is poor to solve, and cures
Afterwards, skin surface easily forms scar, influences skin beauty, is easy the problem of damaging to the psychology of the wounded.
The technical scheme adopted by the invention is that:
The present invention provides a kind of wound surface nursing ointment, each component including following parts by weight: perilla leaf extract 20-50
Part, 15-40 parts of Folium Artemisiae Argyi extract, 10-30 parts of aloe extract, azalea 10-40 parts of root powder, epidermal growth factor 10-30
Part, 20-60 parts of albolene, 30-60 parts of carboxymethyl cellulose, 20-40 parts of polyethylene glycol, 5-15 parts of moisturizer, bleeding agent 10-
35 parts, 80-150 parts of purified water.
Preferably, perilla leaf 32-46 parts, 22-35 parts of folium artemisiae argyi, 18-25 parts of aloe extract, azalea root powder 25-33
Part, is protected 16-26 parts of epidermal growth factor, 33-45 parts of albolene, 42-53 parts of carboxymethyl cellulose, 25-30 parts of polyethylene glycol
8-13 parts of humectant, 20-32 parts of bleeding agent, 100-130 parts of purified water.
Preferably, 40 parts of perilla leaf, 32 parts of folium artemisiae argyi, 20 parts of aloe extract, azalea 28 parts of root powder, epidermal growth factor
22 parts of son, 42 parts of albolene, 50 parts of carboxymethyl cellulose, 27 parts of polyethylene glycol, 11 parts of moisturizer, 28 parts of bleeding agent, purifying
122 parts of water.
Preferably, the molecular weight of the polyethylene glycol is 300-6000.
Preferably, the moisturizer be one of glycerol, Sodium Hyaluronate, sorbierite or more than one mixture,
The bleeding agent is one of menthol, borneol, Laurocapram, volatile clove oil, eucalyptus oil.
Preferably, the perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times,
Amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, and merging is decocted three times
After liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh Folium Artemisiae Argyi powder
After broken, add water to cook three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, decoct 2 respectively three times, 1,
It 0.5 hour, after merging decocting liquid three times, filtered, be concentrated into thick paste, be spray dried to fine powder.
Preferably, the aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: take Chinese aloe leaf by its
Gel position is collected to container, and a certain amount of propylene glycol and purified water dilution, the aloe gel: the third two are proportionally added into
Alcohol: the mass ratio of purified water is 3:1:1, to get required aloe extract after three is uniformly mixed.
Preferably, the root powder of the azalea be azalea root through over cleaning, dry, crush after, with 40 mesh screen mistakes
Filter obtained pulvis.
The present invention also provides a kind of preparation methods of wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 100-
The stirring rate of 150r/min stirs 20-40min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 15-30min under normal temperature conditions,
30-50min is stirred with the stirring rate of 60-100r/min, albolene, polyethylene glycol is sequentially added in whipping process, stirs
After mixing, it is spare to obtain component two；
Step E: moisturizer, bleeding agent are added in remaining purified water, with the stirring rate of 60-100r/min under normal temperature condition
30-50min is stirred, epidermal growth factor is added in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 100-120r/min
40-60min is mixed, component three is added in whipping process, after stirring and evenly mixing, using homogenizer homogeneous 1h-3h to get wound surface
Nurse ointment.
Preferably, the stirring rate in the step C is 138r/min, mixing time 33min.
Preferably, the soaking time in the step D is 23min, stirring rate 86r/min, and mixing time is
44min。
Preferably, the stirring rate in the step E is 78r/min, mixing time 40min.
Preferably, the stirring rate in the step F is 112r/min, mixing time 52min, and homogenizing time is
1.3h。
Compared with prior art, the beneficial effects of the present invention are:
1, wound surface of the present invention nurses ointment, tends to smear out, removes, and has advantage especially for the rotten to the corn surface of a wound, for
Wound fluid and secretion can play absorption, have good adhesion and coating, each dispersion of medicine, matter
Amount is stablized, character is good, and consistency is suitable for being suitble to clinical application.
2, wound surface of the present invention nurses ointment, and irritation is small, highly-safe, good effect, because to contain epidermis raw for it
The ingredients such as the long factor can provide nutrition for skin, promote the quick reparation and healing of skin histology, after healing, skin surface
It not will form scar, do not influence skin beauty.
3, the preparation method of wound surface nursing ointment of the present invention, preparation process is simple, raw material sources are extensive, system
Standby low in cost, wide market.
Specific embodiment
Embodiment one
There is provided a kind of wound surface nursing ointment, each component including following parts by weight: 20 parts of perilla leaf extract, folium artemisiae argyi are extracted
15 parts of object, 10 parts of aloe extract, 10 parts of the root powder of azalea, 10 parts of epidermal growth factor, 20 parts of albolene, carboxymethyl are fine
Tie up plain 30 parts, 20 parts of polyethylene glycol, 5 parts of moisturizer, 10 parts of bleeding agent, 80 parts of purified water.
The molecular weight of the polyethylene glycol is 300-6000.
The moisturizer is the mixture of glycerol, Sodium Hyaluronate, and the bleeding agent is menthol.
The perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, three times plus
Water is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, after merging decocting liquid three times, is passed through
It filters, be concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water
It decocts three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, is closed
And three times after decocting liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder.
The aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: taking Chinese aloe leaf by its gel section
Position is collected to container, is proportionally added into a certain amount of propylene glycol and purified water dilution, the aloe gel: propylene glycol: purifying
The mass ratio of water is 3:1:1, to get required aloe extract after three is uniformly mixed.
The root powder of the azalea be azalea root through over cleaning, dry, crush after, be obtained by filtration with 40 mesh screens
Pulvis.
The preparation method of above-mentioned wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 138r/
The stirring rate of min stirs 33min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 23min under normal temperature conditions, with
The stirring rate of 86r/min stirs 44min, sequentially adds albolene, polyethylene glycol in whipping process, after stirring and evenly mixing, obtains
Component two is spare；
Step E: moisturizer, bleeding agent are added in remaining purified water, stirred under normal temperature condition with the stirring rate of 78r/min
40min is added epidermal growth factor in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 112r/min
Component three is added in whipping process by 52min, after stirring and evenly mixing, nurses using homogenizer homogeneous 1.3h to get wound surface soft
Cream.
Embodiment two
A kind of wound surface nursing ointment, each component including following parts by weight: 40 parts of perilla leaf, 32 parts of folium artemisiae argyi, aloe are provided
20 parts of extract, 22 parts of epidermal growth factor, 42 parts of albolene, 50 parts of carboxymethyl cellulose, gathers 28 parts of the root powder of azalea
27 parts of ethylene glycol, 11 parts of moisturizer, 28 parts of bleeding agent, 122 parts of purified water.
The molecular weight of the polyethylene glycol is 300-6000.
The moisturizer is sorbierite, and the bleeding agent is eucalyptus oil.
The perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, three times plus
Water is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, after merging decocting liquid three times, is passed through
It filters, be concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water
It decocts three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, is closed
And three times after decocting liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder.
The aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: taking Chinese aloe leaf by its gel section
Position is collected to container, is proportionally added into a certain amount of propylene glycol and purified water dilution, the aloe gel: propylene glycol: purifying
The mass ratio of water is 3:1:1, to get required aloe extract after three is uniformly mixed.
The root powder of the azalea be azalea root through over cleaning, dry, crush after, be obtained by filtration with 40 mesh screens
Pulvis.
The preparation method of above-mentioned wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 138r/
The stirring rate of min stirs 33min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 23min under normal temperature conditions, with
The stirring rate of 86r/min stirs 44min, sequentially adds albolene, polyethylene glycol in whipping process, after stirring and evenly mixing, obtains
Component two is spare；
Step E: moisturizer, bleeding agent are added in remaining purified water, stirred under normal temperature condition with the stirring rate of 78r/min
40min is added epidermal growth factor in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 112r/min
Component three is added in whipping process by 52min, after stirring and evenly mixing, nurses using homogenizer homogeneous 1.3h to get wound surface soft
Cream.
Embodiment three
There is provided a kind of wound surface nursing ointment, each component including following parts by weight: 50 parts of perilla leaf extract, folium artemisiae argyi are extracted
40 parts of object, 30 parts of aloe extract, 40 parts of the root powder of azalea, 30 parts of epidermal growth factor, 60 parts of albolene, carboxymethyl are fine
Tie up plain 60 parts, 40 parts of polyethylene glycol, 15 parts of moisturizer, 35 parts of bleeding agent, 150 parts of purified water.
The molecular weight of the polyethylene glycol is 300-6000.
The moisturizer is glycerol, and the bleeding agent is Laurocapram.
The perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, three times plus
Water is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, after merging decocting liquid three times, is passed through
It filters, be concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water
It decocts three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, is closed
And three times after decocting liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder.
The aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: taking Chinese aloe leaf by its gel section
Position is collected to container, is proportionally added into a certain amount of propylene glycol and purified water dilution, the aloe gel: propylene glycol: purifying
The mass ratio of water is 3:1:1, to get required aloe extract after three is uniformly mixed.
The root powder of the azalea be azalea root through over cleaning, dry, crush after, be obtained by filtration with 40 mesh screens
Pulvis.
The preparation method of above-mentioned wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 138r/
The stirring rate of min stirs 33min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 23min under normal temperature conditions, with
The stirring rate of 86r/min stirs 44min, sequentially adds albolene, polyethylene glycol in whipping process, after stirring and evenly mixing, obtains
Component two is spare；
Step E: moisturizer, bleeding agent are added in remaining purified water, stirred under normal temperature condition with the stirring rate of 78r/min
40min is added epidermal growth factor in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 112r/min
Component three is added in whipping process by 52min, after stirring and evenly mixing, nurses using homogenizer homogeneous 1.3h to get wound surface soft
Cream.
Example IV
A kind of wound surface nursing ointment, each component including following parts by weight: 40 parts of perilla leaf, 32 parts of folium artemisiae argyi, aloe are provided
20 parts of extract, 22 parts of epidermal growth factor, 42 parts of albolene, 50 parts of carboxymethyl cellulose, gathers 28 parts of the root powder of azalea
27 parts of ethylene glycol, 11 parts of moisturizer, 28 parts of bleeding agent, 122 parts of purified water.
The molecular weight of the polyethylene glycol is 300-6000.
The moisturizer is sorbierite, and the bleeding agent is eucalyptus oil.
The perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, three times plus
Water is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, after merging decocting liquid three times, is passed through
It filters, be concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water
It decocts three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, is closed
And three times after decocting liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder.
The aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: taking Chinese aloe leaf by its gel section
Position is collected to container, is proportionally added into a certain amount of propylene glycol and purified water dilution, the aloe gel: propylene glycol: purifying
The mass ratio of water is 3:1:1, to get required aloe extract after three is uniformly mixed.
The root powder of the azalea be azalea root through over cleaning, dry, crush after, be obtained by filtration with 40 mesh screens
Pulvis.
The preparation method of above-mentioned wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 100r/
The stirring rate of min stirs 20min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 15min under normal temperature conditions, with
The stirring rate of 60r/min stirs 30min, sequentially adds albolene, polyethylene glycol in whipping process, after stirring and evenly mixing, obtains
Component two is spare；
Step E: moisturizer, bleeding agent are added in remaining purified water, stirred under normal temperature condition with the stirring rate of 60r/min
30min is added epidermal growth factor in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 100r/min
Component three is added in whipping process by 40min, after stirring and evenly mixing, nurses using homogenizer homogeneous 1h to get wound surface soft
Cream.
Embodiment five
A kind of wound surface nursing ointment, each component including following parts by weight: 40 parts of perilla leaf, 32 parts of folium artemisiae argyi, aloe are provided
20 parts of extract, 22 parts of epidermal growth factor, 42 parts of albolene, 50 parts of carboxymethyl cellulose, gathers 28 parts of the root powder of azalea
27 parts of ethylene glycol, 11 parts of moisturizer, 28 parts of bleeding agent, 122 parts of purified water.
The molecular weight of the polyethylene glycol is 300-6000.
The moisturizer is sorbierite, and the bleeding agent is borneol.
The perilla leaf extract the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, three times plus
Water is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, after merging decocting liquid three times, is passed through
It filters, be concentrated into thick paste, be spray dried to fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water
It decocts three times, amount of water three times is respectively 3 times of perilla leaf weight, 2 times, 1 times, is decocted 2,1,0.5 hours respectively three times, is closed
And three times after decocting liquid, is filtered, is concentrated into thick paste, be spray dried to fine powder.
The aloe extract is the thick liquid of colorless and odorless, and preparation method is as follows: taking Chinese aloe leaf by its gel section
Position is collected to container, is proportionally added into a certain amount of propylene glycol and purified water dilution, the aloe gel: propylene glycol: purifying
The mass ratio of water is 3:1:1, to get required aloe extract after three is uniformly mixed.
The root powder of the azalea be azalea root through over cleaning, dry, crush after, be obtained by filtration with 40 mesh screens
Pulvis.
The preparation method of above-mentioned wound surface nursing ointment, the specific steps are as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 150r/
The stirring rate of min stirs 40min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 30min under normal temperature conditions, with
The stirring rate of 100r/min stirs 50min, sequentially adds albolene, polyethylene glycol in whipping process, after stirring and evenly mixing, obtains
Component two is spare；
Step E: moisturizer, bleeding agent are added in remaining purified water, stirred under normal temperature condition with the stirring rate of 100r/min
50min is mixed, epidermal growth factor is added in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 120r/min
Component three is added in whipping process by 60min, after stirring and evenly mixing, nurses using homogenizer homogeneous 3h to get wound surface soft
Cream.
Specific embodiments of the present invention are only a part of the embodiments of the present invention, instead of all the embodiments, are not constituted
Limitation of the present invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not before making creative work
Every other embodiment obtained is put, shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of wound surface nurses ointment, which is characterized in that each component including following parts by weight: perilla leaf extract 20-
50 parts, 15-40 parts of Folium Artemisiae Argyi extract, 10-30 parts of aloe extract, azalea 10-40 parts of root powder, epidermal growth factor 10-
30 parts, 20-60 parts of albolene, 30-60 parts of carboxymethyl cellulose, 20-40 parts of polyethylene glycol, 5-15 parts of moisturizer, bleeding agent
10-35 parts, 80-150 parts of purified water.
2. wound surface according to claim 1 nurses ointment, which is characterized in that each component including following parts by weight:
32-46 parts of perilla leaf, 22-35 parts of folium artemisiae argyi, 18-25 parts of aloe extract, 25-33 parts of the root powder of azalea, epidermal growth factor
16-26 parts, 33-45 parts of albolene, 42-53 parts of carboxymethyl cellulose, 25-30 parts of polyethylene glycol, 8-13 parts of moisturizer, infiltration
20-32 parts of agent, 100-130 parts of purified water.
3. wound surface according to claim 2 nurses ointment, which is characterized in that each component including following parts by weight:
40 parts of perilla leaf, 32 parts of folium artemisiae argyi, 20 parts of aloe extract, 28 parts of the root powder of azalea, 22 parts of epidermal growth factor, albolene
42 parts, 50 parts of carboxymethyl cellulose, 27 parts of polyethylene glycol, 11 parts of moisturizer, 28 parts of bleeding agent, 122 parts of purified water.
4. wound surface according to claim 1 nurses ointment, which is characterized in that the molecular weight of the polyethylene glycol is
300-6000。
5. wound surface according to claim 1 nurses ointment, which is characterized in that the moisturizer is glycerol, hyalomitome
One of sour sodium, sorbierite or more than one mixture, the bleeding agent are menthol, borneol, Laurocapram, cloves
One of volatile oil, eucalyptus oil.
6. wound surface according to any one of claims 1-5 nurses ointment, which is characterized in that the perilla leaf extracts
Object the preparation method comprises the following steps: by fresh perilla leaf crush after, add water to cook three times, amount of water three times is respectively perilla leaf weight
3 times, 2 times, 1 times decoct 2,1,0.5 hours respectively three times, after merging decocting liquid three times, are filtered, are concentrated into thick paste, are spray-dried
At fine powder；The Folium Artemisiae Argyi extract the preparation method comprises the following steps: by fresh folium artemisiae argyi crush after, add water to cook three times, amount of water three times
Respectively 3 times, 2 times, 1 times of perilla leaf weight decoct 2,1,0.5 hours respectively three times, after merging decocting liquid three times, filtered,
It is concentrated into thick paste, is spray dried to fine powder.
7. wound surface according to claim 6 nurses ointment, which is characterized in that the aloe extract is colourless nothing
The thick liquid of taste, preparation method are as follows: taking Chinese aloe leaf to collect at its gel position to container, be proportionally added into a certain amount of
Propylene glycol and purified water dilution, the aloe gel: propylene glycol: the mass ratio of purified water be 3:1:1, three is stirred
To get required aloe extract after uniformly.
8. wound surface according to claim 7 nurses ointment, which is characterized in that the root powder of the azalea is cuckoo
Colored root through over cleaning, dry, crush after, the pulvis that is obtained by filtration with 40 mesh screens.
9. according to benefit require 8 described in wound surface nursing ointment preparation method, which is characterized in that specific step is as follows:
Step A: spare after being weighed according to the proportion speed of each component；
Step B: prepare perilla leaf extract, Folium Artemisiae Argyi extract, aloe extract, azalea root powder, it is spare；
Step C: the root powder of perilla leaf extract, Folium Artemisiae Argyi extract, azalea is sequentially added in aloe extract, with 100-
The stirring rate of 150r/min stirs 20-40min, and after stirring and evenly mixing, it is spare to obtain component one；
Step D: carboxymethyl cellulose being added to etc. in the purified water of mass parts, after impregnating 15-30min under normal temperature conditions,
30-50min is stirred with the stirring rate of 60-100r/min, albolene, polyethylene glycol is sequentially added in whipping process, stirs
After mixing, it is spare to obtain component two；
Step E: moisturizer, bleeding agent are added in remaining purified water, with the stirring rate of 60-100r/min under normal temperature condition
30-50min is stirred, epidermal growth factor is added in whipping process, after stirring and evenly mixing, it is spare to obtain component three；
Step F: component two being added in component one and is mixed, and is stirred under normal temperature condition with the stirring rate of 100-120r/min
40-60min is mixed, component three is added in whipping process, after stirring and evenly mixing, using homogenizer homogeneous 1h-3h to get wound surface
Nurse ointment.
10. the preparation method of wound surface nursing ointment according to claim 9, which is characterized in that in the step C
Stirring rate is 138r/min, mixing time 33min.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266373A (en) * | 2011-08-04 | 2011-12-07 | 上海美宝生命科技有限公司 | Skin externally-used matrix for treating scar and preparation method thereof |
| CN104288828A (en) * | 2014-10-29 | 2015-01-21 | 广西信业生物技术有限公司 | Medical biological scar-inhibiting rhytidectomy dressing and preparation method thereof |
| CN105687797A (en) * | 2016-03-17 | 2016-06-22 | 徐美英 | Medicine preparation for treating burns and scalds and application of medicine preparation |
| CN107376004A (en) * | 2017-06-29 | 2017-11-24 | 广东泰宝医疗器械技术研究院有限公司 | A kind of polyethylene glycol medical dressing and preparation method thereof |
| CN108210887A (en) * | 2017-11-27 | 2018-06-29 | 南京天纵易康生物科技股份有限公司 | A kind of Medical cold application and preparation method thereof |
-
2019
- 2019-02-26 CN CN201910144129.2A patent/CN109865126A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266373A (en) * | 2011-08-04 | 2011-12-07 | 上海美宝生命科技有限公司 | Skin externally-used matrix for treating scar and preparation method thereof |
| CN104288828A (en) * | 2014-10-29 | 2015-01-21 | 广西信业生物技术有限公司 | Medical biological scar-inhibiting rhytidectomy dressing and preparation method thereof |
| CN105687797A (en) * | 2016-03-17 | 2016-06-22 | 徐美英 | Medicine preparation for treating burns and scalds and application of medicine preparation |
| CN107376004A (en) * | 2017-06-29 | 2017-11-24 | 广东泰宝医疗器械技术研究院有限公司 | A kind of polyethylene glycol medical dressing and preparation method thereof |
| CN108210887A (en) * | 2017-11-27 | 2018-06-29 | 南京天纵易康生物科技股份有限公司 | A kind of Medical cold application and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 娄玉铃主编: "《中国痹病大全》", 1 October 1993, 中国科学技术出版社 * |
| 时霄霄主编: "《邹平中药志》", 30 January 2015, 中医古籍出版社 * |
| 苗明三主编: "《法定中药药理与临床》", 30 October 1998, 世界图书出版公司 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114028299A (en) * | 2021-12-20 | 2022-02-11 | 浙江卡莱卡生物科技有限公司 | Fibrous ointment for wound surface nursing and preparation method thereof |
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