CN108300625A - A kind of health liquor adjusting female endocrine dyscrasia - Google Patents
A kind of health liquor adjusting female endocrine dyscrasia Download PDFInfo
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- CN108300625A CN108300625A CN201710020638.5A CN201710020638A CN108300625A CN 108300625 A CN108300625 A CN 108300625A CN 201710020638 A CN201710020638 A CN 201710020638A CN 108300625 A CN108300625 A CN 108300625A
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- flavones
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- endocrine dyscrasia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G1/00—Preparation of wine or sparkling wine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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Abstract
The present invention discloses a kind of health liquor adjusting female endocrine dyscrasia, including following raw material:3 15 parts of Procyanidins From Hawthorn Fruit, 5 30 parts of Carica papaya flavonoids, 5 30 parts of Longstamen Onion Bulb polysaccharide, 5 25 parts of fructus cannabis flavones, surplus is grape wine, 1000 parts in total.Four kinds of drugs of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones in health liquor of the present invention are coordinated to use, and relax strongly fragrant through promoting blood circulation, helping the five internal organs, promoting the circulation of qi to dissipate, reach and adjust endocrine effect.
Description
Technical field
The invention belongs to field of health care products, and in particular to a kind of health liquor adjusting female endocrine dyscrasia.
Background technology
Human body has internal system, secretes metabolism and physiological function that various hormones and nervous system adjust human body together.
Various hormones are to maintain balance under normal circumstances, such as because certain reason makes this balance break, will result in endocrine mistake
It adjusts, causes corresponding clinical manifestation.There are physiologic factor, trophic factor, emotional factor and environment in the reason of causing endocrine disorder
Factor.And with the exacerbation of environmental pollution, after some chemicals in air enter human body through various channels, process is a series of
Chemical reaction, lead to endocrine disorder, women made the problems such as menstrual disorder, endometrial hyperplasia occur.Endocrine is lost
Assign women to bring very big puzzlement, as skin deteriorate, it is short-tempered.There is gynecological disease in severe patient, as menstrual flow is irregular, pain
Through causing what is more infertile.
Patent ZL201210421168.0 discloses a kind of Chinese medicine composition adjusting female endocrine dyscrasia, the composition
Including following raw material:10-15 parts of Radix Astragali, 10-15 parts of Radix Angelicae Sinensis, 10-15 parts of motherwort, 5-10 parts of lily, Chinese yam 5-10
Part, 1-5 parts of the root of Dahurain angelica, 1-5 parts of prepared rehmannia root, 1-5 parts of peach kernel, 1-2 parts of Poria cocos, 1-2 parts of radix paeoniae rubra, 1-2 parts of tortoise plastron.The composition passes through
Blood circulation promoting and enriching, relax meridian and relieving pain, kidney and spleen invigorating, the effects that moistening the lung and nourish yin, play point effect in adjusting.It is usually used in adjusting interior point at present
That secretes has the Chinese medicines such as motherwort, Siwu Tang, but the Chinese drugs agentia should not be used for a long time.
Invention content
The object of the present invention is to provide a kind of health liquors adjusting female endocrine dyscrasia, and the health liquor is according to Traditional Chinese health
Theory is formulated each taste medicine phases and mutually cooperates in conjunction with women physique characteristic, relaxes strongly fragrant through promoting blood circulation, helping the five internal organs, promoting the circulation of qi to dissipate, reaches in adjusting
The effect of secretion.
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:
Preferably, the health liquor for adjusting female endocrine dyscrasia, including following raw material:
It is furthermore preferred that the health liquor for adjusting female endocrine dyscrasia, including following raw material:
Most preferably, the health liquor for adjusting female endocrine dyscrasia, including following raw material:
Preferably, the Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide and fructus cannabis flavones weight part ratio are 6-11:
8-15:10-20:10-18。
It is furthermore preferred that the Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide and fructus cannabis flavones weight part ratio are 8-
10:10-15:15-18:15-18。
Preferably, the grape wine is white wine, Alcohol degree 12-14%vol.
The Female health wine of the present invention for improving sleep, preparation method includes the following steps:
1) it allocates:Black Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and grape wine are placed in blend tank
In, after stirring and dissolving is uniform, obtain mixed liquor;
2) it stands:Mixed liquor stands 2~3 days;
3) it filters:Using nuclepore membrane filter, pore size filter is 0.2~0.8 μm;
4) filling:It is filling in capacity be 750mL burgundy bottle in.
Preferably, micro porous filtration membrane aperture is 0.45~0.65 μm.Miillpore filter aperture is excessive, and solid particle polluter has
Part remains, and influences the clarity of wine.
Procyanidins From Hawthorn Fruit is extracted from hawthorn ripening fruits, is had stronger antioxidant activity and is removed certainly
By base ability.Glucosidase procyanidins in hawthorn anthocyanidin can keep blood vessel elasticity, and adjusting microcirculation is anti-inflammatory, makes the battalion in blood
Foster substance can lead to capillary.
Carica papaya flavonoids are to dry in almost ripe fruit to extract from rosaceous plant chaenomeles lagenaria, are relaxed with soothing the liver
Muscle, active, spleen benefiting and stimulating the appetite, Shugan Zhitong and other effects.In addition, it, which also has, removes human body active oxygen radical, biomembrane is prevented
Lipid is aoxidized by superoxide radical and hydroxy radical.
Longstamen Onion Bulb polysaccharide is extracted from the dry bulb of liliaceous plant Allium macrostemon, is had and is activated yang and removed abstruction, goes
The stagnant effect of conductance.In addition, it also has phlegm reduction of blood circulation promoting, warm yang transforming qi and other effects.
Fructus cannabis flavones is extracted from the benevolence of moraceae plants hemp, has effects that promoting diuresis for stranguria, promoting blood circulation,
Also there is calm, anticonvulsion and improvement sleep effect.
The present invention is equipped with Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide and fructus cannabis flavones using grape wine as base liquor,
Blood vessel can be promoted to absorb active principle, grape wine has qualcomm meridian effect in addition, and the Chinese medicine in the present invention can be accelerated to absorb, reached
To the endocrine effect of adjusting.
Compared with prior art, the beneficial effects of the invention are as follows:(1) middle the effective elements of the medicine is added directly into grape wine
In, improve the defect that soaking time in Traditional health care wine preparation process is long, active ingredient dissolution rate is low and dissolution component is miscellaneous;
(2) using grape wine as base liquor, belong to alkaline drink wine, Alcohol degree is low, is suitble to women, can adjust constitution acidity degree;(3)
Four kinds of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones drugs are coordinated to use, and relax through promoting blood circulation, helping the five internal organs, row
Gas dissipates strongly fragrant, reaches and adjusts endocrine effect;(4) raw material is all to belong to as defined in food and medicine Surveillance Authority that medicine-food two-purpose can
For the substance of health food, have no toxic side effect.
Specific implementation mode
With reference to specific embodiment, the present invention is further described, but embodiment of the present invention is not limited only to this.
Embodiment 1
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:3 parts of Procyanidins From Hawthorn Fruit, wood
9 parts of melon flavones, 20 parts of Longstamen Onion Bulb polysaccharide, 25 parts of fructus cannabis flavones, surplus be 12%vol white wine, totally 1000 parts.
Preparation method:By the white grape of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 12%vol
Wine is placed in blend tank, after stirring and dissolving is uniform, obtains mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, filtering
Aperture is 0.8 μm;It is filling in capacity be 750mL burgundy bottle in.
Embodiment 2
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:6 parts of Procyanidins From Hawthorn Fruit, wood
20 parts of melon flavones, 30 parts of Longstamen Onion Bulb polysaccharide, 5 parts of fructus cannabis flavones, surplus be 12%vol red wine, totally 1000 parts.
Preparation method:By the red grape of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 12%vol
Wine is placed in blend tank, after stirring and dissolving is uniform, obtains mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, filtering
Aperture is 0.65 μm;It is filling in capacity be 750mL burgundy bottle in.
Embodiment 3
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:15 parts of Procyanidins From Hawthorn Fruit, wood
5 parts of melon flavones, 5 parts of Longstamen Onion Bulb polysaccharide, 9 parts of fructus cannabis flavones, surplus be 14%vol white wine, totally 1000 parts.
Preparation method:By the white grape of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 14%vol
Wine is placed in blend tank, after stirring and dissolving is uniform, obtains mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, filtering
Aperture is 0.22 μm;It is filling in capacity be 750mL burgundy bottle in.
Embodiment 4
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:10 parts of Procyanidins From Hawthorn Fruit, wood
15 parts of melon flavones, 13 parts of Longstamen Onion Bulb polysaccharide, 16 parts of fructus cannabis flavones, surplus be 13%vol white wine, totally 1000 parts.
Preparation method:By the white grape of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 13%vol
Wine is placed in blend tank, after stirring and dissolving is uniform, obtains mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, filtering
Aperture is 0.45 μm;It is filling in capacity be 750mL burgundy bottle in.
Embodiment 5
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:12 parts of Procyanidins From Hawthorn Fruit, wood
18 parts of melon flavones, 8 parts of Longstamen Onion Bulb polysaccharide, 20 parts of fructus cannabis flavones, surplus be 14%vol white wine, totally 1000 parts.
Preparation method:By the white grape of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 14%vol
Wine is placed in blend tank, after stirring and dissolving is uniform, obtains mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, filtering
Aperture is 0.45 μm;It is filling in capacity be 750mL burgundy bottle in.
Comparative example 1
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:12 parts of Procyanidins From Hawthorn Fruit, wood
18 parts of melon flavones, 20 parts of fructus cannabis flavones, surplus be 14%vol white wine, totally 1000 parts.
Preparation method:The white wine of Procyanidins From Hawthorn Fruit, Carica papaya flavonoids, fructus cannabis flavones and 14%vol are placed in tune
In distribution tank, after stirring and dissolving is uniform, mixed liquor is obtained;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is
0.45μm;It is filling in capacity be 750mL burgundy bottle in.
Comparative example 2
A kind of health liquor adjusting female endocrine dyscrasia, including following raw material:12 parts of Procyanidins From Hawthorn Fruit, Chinese onion
White 8 parts of polysaccharide, 20 parts of fructus cannabis flavones, surplus are the white wine of 14%vol, totally 1000 parts.
Preparation method:The white wine of Procyanidins From Hawthorn Fruit, Longstamen Onion Bulb polysaccharide, fructus cannabis flavones and 14%vol are placed in tune
In distribution tank, after stirring and dissolving is uniform, mixed liquor is obtained;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is
0.45μm;It is filling in capacity be 750mL burgundy bottle in.
Adjust endocrine efficacy test
160 female incretion patients are randomly selected, the age, sick time was suffered between 1-5 between 18-55 Sui
Person's clinical symptoms are:Swollen breasts, dysmenorrhoea, menstrual disorder, acne, constipation, short-tempered, insomnia.
Above-mentioned patient is equally divided into 8 groups, there was no significant difference between each group.This 9 groups of patients are taken into placebo respectively
Blank control, the health liquor of embodiment 1-5 and comparative example 1-2 health liquor, taken before sleeping daily, each 20mL continuously takes 2
Observing effect after a month.
Criterion of therapeutical effect is fully recovered:Endocrine manifestations all disappear, and endocrine restores normal;It is effective:Swollen breasts, dysmenorrhoea, the moon
It disappears substantially through imbalance, acne, constipation, short-tempered, insomnia;Effectively:Swollen breasts, dysmenorrhoea, menstrual disorder, acne,
Constipation, short-tempered, insomnia are clearly better, and endocrine disorder makes moderate progress;In vain:Endocrine disorder, each clinical symptoms are without changing
It is kind.
1 curative effect statistical form of table
Group | Recovery from illness | It is effective | Effectively | In vain | It is total | Efficient (%) |
Blank control | 0 | 0 | 0 | 0 | 0 | 0 |
Embodiment 1 | 3 | 10 | 5 | 2 | 18 | 90 |
Embodiment 2 | 3 | 9 | 6 | 2 | 18 | 90 |
Embodiment 3 | 3 | 10 | 5 | 2 | 18 | 90 |
Embodiment 4 | 6 | 11 | 2 | 1 | 19 | 95 |
Embodiment 5 | 5 | 10 | 4 | 1 | 19 | 95 |
Comparative example 1 | 0 | 0 | 4 | 0 | 4 | 20 |
Comparative example 2 | 0 | 0 | 3 | 0 | 3 | 16.7 |
As seen from Table 1, test group treats endocrine disorder, and high efficiency is up to 95%, and comparative example effective percentage is only
16.7%-20% illustrates that the health liquor of the present invention adjusts endocrine disorder significant effect.
Claims (7)
1. a kind of health liquor adjusting female endocrine dyscrasia, which is characterized in that including following raw material:
2. a kind of health liquor adjusting female endocrine dyscrasia as described in claim 1, which is characterized in that including following weight
Part raw material:
3. a kind of health liquor adjusting female endocrine dyscrasia as described in claim 1, which is characterized in that including following weight
Part raw material:
4. a kind of health liquor adjusting female endocrine dyscrasia as described in any one of claims 1-3, which is characterized in that including
Following raw material:
5. a kind of health liquor adjusting female endocrine dyscrasia as described in claim 1, which is characterized in that the hawthorn original flower
Green element, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide and fructus cannabis flavones weight part ratio are 6-11:8-15:10-20:10-18.
6. a kind of health liquor adjusting female endocrine dyscrasia as claimed in claim 5, which is characterized in that the hawthorn original flower
Green element, Carica papaya flavonoids, Longstamen Onion Bulb polysaccharide and fructus cannabis flavones weight part ratio are 8-10:10-15:15-18:15-18.
7. a kind of health liquor adjusting female endocrine dyscrasia as described in any one of claims 1-3, which is characterized in that described
Grape wine is white wine, Alcohol degree 12-14%vol.
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