CN108295218B - Formula of plaster for treating acute soft tissue injury - Google Patents
Formula of plaster for treating acute soft tissue injury Download PDFInfo
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- CN108295218B CN108295218B CN201810206177.5A CN201810206177A CN108295218B CN 108295218 B CN108295218 B CN 108295218B CN 201810206177 A CN201810206177 A CN 201810206177A CN 108295218 B CN108295218 B CN 108295218B
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- soft tissue
- tissue injury
- plaster
- treating acute
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a formula of a plaster for treating acute soft tissue injury, which is prepared from the following raw material medicines in parts by weight: 8-12 parts of ground beetle, 8-12 parts of celandine, 6-10 parts of rheum officinale, 6-10 parts of angelica sinensis, 6-10 parts of turmeric and 2-10 parts of mature vinegar. The plaster for treating acute soft tissue disclosed by the invention can play roles in resisting inflammation, relieving swelling and pain, promoting blood circulation to remove blood stasis and accelerating the repair of soft tissue injury by adopting an external application method, is quick in effect and short in treatment course when used for treating acute soft tissue injury, and can achieve the purpose of curing acute soft tissue injury by continuous use. Clinical research shows that the total effective rate of the traditional Chinese medicine composition for treating acute soft tissue injury reaches 96.3 percent.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a formula of a plaster for treating acute soft tissue injury.
Background
Acute soft tissue injury is one of common clinical diseases, which causes patients to have pain, and the main symptoms of the acute soft tissue injury are blood stasis, swelling and pain. The reason is that after the local structure is affected by the injury-causing factor, the local tissue is damaged by acute aseptic inflammation reaction, microcirculation disturbance and the like, the hemodynamics is changed, the vascular permeability is increased, the exudation is increased, the swelling is increased, the nerve endings act to dredge inflammatory mediators, and pain is caused, and the local aseptic inflammation reaction is the core of the local aseptic inflammation reaction.
At present, a plurality of medicines and methods for treating acute soft tissue injury have certain effects in both traditional Chinese medicine and western medicine, but have defects. The treatment mode of acute soft tissue injury by western medicine mainly comprises the following steps: cold compress, braking, taking non-steroidal anti-inflammatory drugs, physical therapy (electrotherapy, magnetotherapy, ultrasonic therapy, etc.), drug injection, surgical treatment, etc. It has long treatment course, slow recovery, high cost and common adverse drug reactions. The traditional Chinese medicine adopts traditional Chinese medicine treatment, in particular to an external treatment method of the traditional Chinese medicine, and the local application of the traditional Chinese medicine can directly reach the disease site, so that the traditional Chinese medicine has certain effects of relieving swelling and stopping diseases, has obvious curative effect and less adverse reaction, and is safer than oral administration.
Disclosure of Invention
The invention aims to provide a plaster formula for treating acute soft tissue injury, which has the advantages of anti-inflammation, detumescence, acesodyne, acceleration of soft tissue injury repair, rapid curative effect, low price, strong effect and no toxic or side effect on human body.
The formula of the plaster for treating acute soft tissue injury provided by the invention utilizes unique drug properties of traditional Chinese medicines according to the theory of traditional Chinese medicines, and adopts ground beetle, celandine, rhubarb, angelica, turmeric and mature vinegar to prepare the plaster by a conventional process according to a certain proportion requirement.
The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 8-12 parts of ground beetle, 8-12 parts of celandine, 6-10 parts of rheum officinale, 6-10 parts of angelica sinensis, 6-10 parts of turmeric and 2-10 parts of mature vinegar.
The traditional Chinese medicine raw materials comprise the following components in parts by weight: 10 parts of ground beetle, 10 parts of celandine, 8 parts of rhubarb, 8 parts of angelica, 8 parts of turmeric and 5 parts of mature vinegar.
The pharmacological actions of the traditional Chinese medicine are as follows:
ground beetle: is dried female of Eupolyphaga Seu Steleophaga or JI Eupolyphaga of Corallodiscae, has salty taste and cold property, and has effects of removing blood stasis, promoting reunion of fractured tendons and bones, relieving swelling and pain, promoting lactation and dredging channels. Can be used for treating traumatic injury, injury of tendons and bones, amenorrhea due to blood stasis, puerperal abdominal pain due to blood stasis, and abdominal lump.
Herba Chelidonii: is a kind of perennial herb of Chelidonium of Papaveraceae, and has cone-shaped main root, earthy yellow or dark brown color, and dense fibrous root. The stem is upright, multi-branched, whitish and white, slender and soft. Has cool nature and bitter taste, has the efficacies of spasmolysis, pain relief, inflammation resistance, bacteriostasis, detumescence, diuresis and detoxification, and is used for treating gastrointestinal pain, abdominal pain, dysmenorrheal, jaundice, scabies, sore and swelling, snake and insect bite and detumescence by external application.
Rhubarb: is prepared from dried root and rhizome of radix et rhizoma Rhei Palmati, and radix Et rhizoma Rhei Tangutici, has special smell, bitter and slightly astringent taste, and has effects of clearing away pathogenic accumulation, clearing away heat, purging pathogenic fire, stopping bleeding, removing toxic substances, promoting blood circulation, and dispelling blood stasis.
Chinese angelica: the Chinese medicinal composition is also named as angelica sinensis, western angelica sinensis, angelica sinensis and the like, is a perennial herb with the height of 0.4-1 meter, the flowering phase of 6-7 months and the fruit phase of 7-9 months, is sweet, pungent and warm in nature and taste, has the effects of enriching blood, promoting blood circulation to restore menstrual flow, relieving pain and lubricating intestines, and also has the effects of relieving pain and resisting inflammation.
Turmeric: radix Curcumae, Curcuma rhizome, etc., which are herbaceous for many years, have a plant height of 1-1.5m, developed rhizome, oblong or elliptical leaf, oval or oblong bud, and yellowish corolla; the flowering phase is 8 months; pungent, bitter and warm in nature, can promote qi and blood circulation, induce menstruation to relieve pain, and resist inflammation. It can be used for treating abdominal distention and pain, shoulder pain, pain in arm, heart pain, puerperal blood pain, skin sore, tinea, menoxenia, amenorrhea, and traumatic injury.
Mature vinegar: the vinegar is a vinegar which is stored for a long time after being brewed, is thick brown, clear in liquid state, mellow in vinegar taste, less in precipitate, long in storage time, not easy to deteriorate and the like. Has warm nature and bitter taste, has the functions of promoting blood circulation and removing blood stasis, and has stable property by using mature vinegar as excipient.
Compared with the prior art, the preparation method has the following beneficial effects:
1. the plaster for treating acute soft tissue injury disclosed by the invention is based on the principle of treating soft tissue injury by traditional Chinese medicine, adopts an external application mode, can play the roles of resisting inflammation, relieving swelling and pain, promoting blood circulation to remove blood stasis and accelerating the repair of soft tissue injury, and is quick in effect and short in treatment course when used for treating acute soft tissue injury; meanwhile, the weak drug effect of the oral medicine and the side effect on the body are avoided, the injury is eliminated more quickly, and the recovery time of the soft tissue injury is shortened obviously.
2. The plaster for treating acute soft tissue injury has the advantages of simple and easily obtained raw materials, preparation by using a conventional method, suitability for industrial popularization, and good economic benefit and wide social benefit.
Detailed Description
The present invention will be described in detail with reference to specific embodiments.
Example 1
The plaster for treating acute soft tissue injury is prepared from the following main raw materials: 8 parts of ground beetle, 8 parts of celandine, 6 parts of rhubarb, 6 parts of angelica, 6 parts of turmeric and 5 parts of mature vinegar.
The plaster for treating acute soft tissue injury is prepared by the following steps: grinding Eupolyphaga Seu Steleophaga, herba Chelidonii, radix et rhizoma Rhei, radix Angelicae sinensis, and Curcuma rhizome in a mortar by grinding method, respectively, grinding into fine powder, sieving with 120 mesh sieve, grinding into fine paste, mixing the fine paste powders, adding old vinegar, stirring to viscous state, and stirring for 30 min to obtain plaster
The using method comprises the following steps: the affected part is cleaned and wiped off, the plaster is coated on the non-woven fabric, the non-woven fabric coated with the plaster is covered on the affected part once a day, the affected part can be healed after 7-10 days, and the unhealed part continues to use until the affected part is healed.
Example 2
The plaster for treating acute soft tissue injury is prepared from the following main raw materials: 10 parts of ground beetle, 10 parts of celandine, 8 parts of rhubarb, 8 parts of angelica, 8 parts of turmeric and 6 parts of mature vinegar.
The plaster for treating acute soft tissue injury is prepared by the following steps: grinding the ground beeltle, the celandine, the rhubarb, the angelica and the turmeric respectively in a mortar by adopting a grinding method, sieving the ground powder by a 120-mesh sieve, grinding the ground powder into fine powder, then uniformly mixing all the fine paste powder, finally adding the mature vinegar into the fine paste powder, continuously stirring the mixture while stirring the mixture until the mixture is viscous, and continuously stirring the mixture for 30 minutes to prepare the plaster.
The using method comprises the following steps: the affected part is cleaned and wiped off, the plaster is coated on the non-woven fabric, the non-woven fabric coated with the plaster is covered on the affected part once a day, the affected part can be healed after 7-10 days, and the unhealed part continues to use until the affected part is healed.
Example 3
The plaster for treating acute soft tissue injury is prepared from the following main raw materials: 12 parts of ground beetle, 12 parts of celandine, 10 parts of rhubarb, 10 parts of angelica, 10 parts of turmeric and 10 parts of mature vinegar.
The plaster for treating acute soft tissue injury is prepared by the following steps: grinding the ground beeltle, the celandine, the rhubarb, the angelica and the turmeric respectively in a mortar by adopting a grinding method, sieving the ground powder by a 120-mesh sieve, grinding the ground powder into fine powder, then uniformly mixing all the fine paste powder, finally adding the mature vinegar into the fine paste powder, continuously stirring the mixture while stirring the mixture until the mixture is viscous, and continuously stirring the mixture for 30 minutes to prepare the plaster.
The using method comprises the following steps: the affected part is cleaned and wiped off, the plaster is coated on the non-woven fabric, the non-woven fabric coated with the plaster is covered on the affected part once a day, the affected part can be healed after 7-10 days, and the unhealed part continues to use until the affected part is healed.
The plasters provided in examples 1 to 3 all have good effects on treating acute soft tissue injury, and the excellent effects are further illustrated by taking the plaster provided in example 1 as an example and combining clinical tests.
107 acute soft tissue injury patients are clinically observed in 2015-2017 by the plaster for treating acute soft tissue injury provided by the invention, and the clinical report is as follows:
1. case selection
107 cases of the present invention were selected for the treatment of acute soft tissue injury in 2015 to 2017.
2. Diagnostic criteria
The method is formulated according to the relevant standards in the clinical research guiding principles of new traditional Chinese medicines:
(1) the external injury has definite history, the pain after injury is severe, and swelling, ecchymosis and joint movement dysfunction appear in different degrees locally;
(2) the tenderness of the wound is obvious, local bluish purple ecchymosis can appear, subcutaneous hematoma can appear in severe cases, and wave sign is positive;
(3) swelling or induration, hidden pain, limited limb movement in different degrees;
(4) the X-ray examination excludes fracture, dislocation and osteopathia.
3. Method of treatment
3.1 prescription: 8 parts of ground beetle, 8 parts of celandine, 6 parts of rhubarb, 6 parts of angelica, 6 parts of turmeric and 5 parts of mature vinegar.
3.2 preparation: grinding the ground beeltle, the celandine, the rhubarb, the angelica and the turmeric respectively in a mortar by adopting a grinding method, sieving the ground powder by a 120-mesh sieve, grinding the ground powder into fine powder, then uniformly mixing all the fine paste powder, finally adding the mature vinegar into the fine paste powder, continuously stirring the mixture while stirring the mixture until the mixture is viscous, and continuously stirring the mixture for 30 minutes to prepare the plaster.
3.3 methods of use: cleaning and wiping the pain part, coating the plaster on non-woven fabric, and covering the non-woven fabric coated with the plaster on the affected part once a day, and suspending use when allergic patients occur.
4. Judgment standard of curative effect and treatment result
4.1 therapeutic effect standard:
and (3) healing: the pain symptom and physical sign completely disappear, and the functional activity returns to normal;
the effect is shown: the pain symptom and physical sign basically disappear, and the functional activity basically returns to normal;
the method has the following advantages: the pain symptom is obviously relieved, but slight pain still exists after fatigue, and the functional activity is recovered to some extent;
and (4) invalidation: pain symptoms, signs were not relieved.
4.2 treatment outcome: in 107 patients, 89 patients are clinically cured, 9 patients have obvious effect, 5 patients have effective effect, 4 patients have ineffective effect, the obvious effect rate is 91.6%, and the total effective rate is 96.3%.
5. Typical cases
5.1 Lizhi, male, 15 years old, Happy district of Dandong City, Liaoning province. In 2016 for 10 months, accidentally stepping on an empty sprained ankle joint in the process of basketball playing, coating the plaster on non-woven fabric and covering the non-woven fabric on an affected part according to the grading and scoring standard of acute soft tissue injury symptoms, wherein the local swelling grade III, the pain grade IV, the tenderness grade III and the dysfunction grade III are realized, the swelling subsides in 3 days, no pain or tenderness exists, and the function recovery is realized in ten days.
5.2 Wangzhi, female, 38 years old, Happy district of Dandong City, Liaoning province. In 2016 for 9 months, the patient can fall to the sprained wrist joint in sports, the local swelling is obvious, the pain is difficult to endure, and the patient feels pain when lightly pressing, and the patient can be cured in fifteen days after the medicine is applied.
5.3 Zhang Danshan county building village people, female, 65 years old, Anhui province. People in the happy area of Dandong City of Liaoning province. In 2016, for 3 months, the wrist is accidentally twisted in the housework process, local swelling and pain are difficult to endure, and pain is felt by slight pressure.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that those skilled in the art can make various improvements and modifications without departing from the principle of the present invention, and these improvements and modifications should also be construed as the protection scope of the present invention.
Claims (2)
1. The composition of the ointment for treating acute soft tissue injury is characterized by being prepared from the following raw material medicines in parts by weight:
8-12 parts of ground beetle, 8-12 parts of celandine, 6-10 parts of rheum officinale, 6-10 parts of angelica sinensis, 6-10 parts of turmeric and 2-10 parts of mature vinegar.
2. The composition of the ointment for treating acute soft tissue injury according to claim 1, which is prepared from the following raw material medicines in parts by weight:
10 parts of ground beetle, 10 parts of celandine, 8 parts of rhubarb, 8 parts of angelica, 8 parts of turmeric and 5 parts of mature vinegar.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810206177.5A CN108295218B (en) | 2018-03-13 | 2018-03-13 | Formula of plaster for treating acute soft tissue injury |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810206177.5A CN108295218B (en) | 2018-03-13 | 2018-03-13 | Formula of plaster for treating acute soft tissue injury |
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| CN108295218A CN108295218A (en) | 2018-07-20 |
| CN108295218B true CN108295218B (en) | 2020-12-01 |
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| CN201810206177.5A Active CN108295218B (en) | 2018-03-13 | 2018-03-13 | Formula of plaster for treating acute soft tissue injury |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006032091A2 (en) * | 2004-09-21 | 2006-03-30 | Lavender Hill Projects Pty Ltd | Herbal composition |
| CN103169830A (en) * | 2013-04-09 | 2013-06-26 | 肖才安 | External medicinal liquor for treating closed soft tissue injury |
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2018
- 2018-03-13 CN CN201810206177.5A patent/CN108295218B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006032091A2 (en) * | 2004-09-21 | 2006-03-30 | Lavender Hill Projects Pty Ltd | Herbal composition |
| CN103169830A (en) * | 2013-04-09 | 2013-06-26 | 肖才安 | External medicinal liquor for treating closed soft tissue injury |
Non-Patent Citations (1)
| Title |
|---|
| 三维正脊仪配合消瘀散外敷治疗腰椎间盘突出症;刘兴利等;《吉林中医药》;20060228;第26卷(第02期);第49-50页 * |
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| CN108295218A (en) | 2018-07-20 |
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