CN108295099A - A kind of antiseptic and its application - Google Patents
A kind of antiseptic and its application Download PDFInfo
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- CN108295099A CN108295099A CN201710523759.1A CN201710523759A CN108295099A CN 108295099 A CN108295099 A CN 108295099A CN 201710523759 A CN201710523759 A CN 201710523759A CN 108295099 A CN108295099 A CN 108295099A
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- Prior art keywords
- antiseptic
- sanitary napkins
- water
- wet sanitary
- base material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses the wet sanitary napkins and preparation method thereof of a kind of antiseptic and the application antiseptic, the antiseptic contains following components per 100g：2.0 3.0g pomegranate rind extracts, 3.0 5.0g glycerine, 1.5 2.0g polysorbas20s, 3.0 5.0g propylene glycol, 1.0 1.5g diazonium imidazolidinyl ureas, qs Fragrance, remaining is RO water.The wet sanitary napkins preparation method of the application antiseptic is simple, affine human body, has good fungistatic effect.
Description
Technical field
The present invention relates to a kind of antiseptic and its applications.
Background technology
Wet tissue is Disposable Sanitary Accessory, is chiefly used in such as civil aviaton, hotel, restaurant, exhibition commercial affairs and reception in the past
Place, in recent years as the improvement of people's living standards, the personal consumption amount of wet tissue gradually increases, be mainly used in travelling,
The occasion of the outdoors water inconveniences such as tourism, the also cleaning-nursing etc. of family infant wipe face, wiping with disinfection wet tissue
Hand, it is hygienic and convenient.
Wet sanitary napkins generally consist of two parts：Base material and liquid.Liquid is considered as that wet tissue class product technology is most intensive
Place, should be according to using the different rational design liquid formula of object.
Pomegranate has edible, medicinal and ornamental value, is cultivated extensively in recent years, is mainly distributed on Hebei, Henan, mountain
East, Jiangsu, Anhui, Zhejiang, Jiangxi, Fujian, Taiwan, Hunan, Hubei, Guangdong, Guangxi, Guizhou, Sichuan etc. save (autonomous region).Stone
Pomegranate skin is a kind of important traditional Chinese medicine, and key agents active constituent punicalagins (punicalagin) content of granatum is high
Up to 8.24%, and it is soluble easily in water.In vitro test shows granatum water decoction to staphylococcus aureus, proteus, diphtheria bar
Bacterium has killing effect, has significantly to typhoid fever and paratyphoid, comma bacillus, Pseudomonas aeruginosa, shigella dysenteriae, tubercle bacillus etc.
Inhibiting effect has a variety of dermatophytes different degrees of inhibiting effect, so blue formula trichobacteria, yellow trichobacteria, barber's itch trichobacteria, iron
Rust trichobacteria, Du's big belly formula sporidiole bacteria difficult to understand, acrothesium floccosum etc..
Currently, do not have also in the market it is a kind of using pomegranate rind extract as main antibacterial at applied to wet sanitary napkins and its system
Product in standby field.
Invention content
It is an object of the invention to overcome shortcoming in the prior art, a kind of antiseptic and its application are provided.
The technical solution adopted by the present invention to solve the technical problems is：Provide a kind of antiseptic, per 100g contain with
Lower component：2.0-3.0g pomegranate rind extracts, 3.0-5.0g glycerine, 1.5-2.0g Tween-20s, 3.0-5.0g propylene glycol, 1.0-
1.5g diazonium imidazolidinyl ureas, qs Fragrance, remaining is RO water.
In a preferred embodiment of the invention, contain 1.0-1.5g fragrance per 100g.
In a preferred embodiment of the invention, the pomegranate rind extract is the ethanol extract of granatum.
The present invention provides above-mentioned antiseptics in the application of wet sanitary napkins preparation field, i.e., a kind of health of above-mentioned antiseptic
Wet tissue preparation method, includes the following steps：
(1) it prepares and takes 2.0-3.0g pomegranate rind extracts per 100g antiseptics, be scattered in RO water, it is sweet that 3.0-5.0g is added
Oil stirs evenly, and is warming up to 30-40 DEG C；Then 1.5-2.0g Tween-20s, 3.0-5.0g propylene glycol and 1.0-1.5g diazonium is added
Imidazolidinyl urea is uniformly mixed；1.0-1.5g fragrance is added, adds RO water to 100g, is cooled down at room temperature after stirring evenly, obtained
To antiseptic；
(2) base material of the water intaking prick nonwoven cloth as wet sanitary napkins, is soaked in above-mentioned antiseptic 2-4 hours, when base material is in
Moistening obtains the wet sanitary napkins containing antiseptic without being packed when drop of liquid state.
The present invention also provides a kind of wet sanitary napkins using above-mentioned antiseptic, including above-mentioned antiseptic to resist with this is impregnated with
The spunlace non-woven cloth base material of microbial inoculum.
Compared with the background art, it has the following advantages that the technical program：
(1) antibacterial action for utilizing the active skull cap components in granatum, reduces the application of chemical antimicrobial component, reduces
The injury that chemical raw material is brought in skin long-term accumulation；
(2) antiseptic ingredient is simple, and Tween-20 has toxicity preferably special compared with low activity compared to other surfaces activating agent
Point, diazonium imidazolidinyl urea have effects that drying damp-removing and inhibit the natural bacteriostatic ingredient shape in bacterial growth, with granatum
At synergistic effect, reach good fungistatic effect.
Specific implementation mode
Present disclosure is illustrated below by embodiment：
Embodiment 1
A kind of antiseptic of the present embodiment contains following components per 100g：2.5g pomegranate rind extracts, 3.5g glycerine,
1.5g Tween-20s, 3.0g propylene glycol, 1.0g diazonium imidazolidinyl ureas, 1.5g fragrance, 87gRO water.The pomegranate rind extract is adopted
With the product of the Xi'an bio tech ltd Yuan Sen, product identification：YSS-003.Pomegranate rind extract has relieving diarrhea with astringents, only
The effect of blood, expelling parasite.It is usually used in chronic diarrhea, protracted dysentery is had blood in stool, rectal prolapse, uterine bleeding, under band, abdominal pain due to enterositosis.Mainly contain tannin, flavones
Class and its glucosides, alkaloid and organic acid etc., external application have the effects that antiviral, broad-spectrum antiseptic, anti-oxidant, immunological regulation.
Above-mentioned antiseptic is applied to wet sanitary napkins preparation method, is included the following steps：
(1) it prepares and takes 2.5g pomegranate rind extracts per 100g antiseptics, be scattered in RO water, it is equal that the stirring of 3.5g glycerine is added
It is even, it is warming up to 30-40 DEG C；Then 1.5g Tween-20s, 3.0 propylene glycol is added, 1.0g diazonium imidazolidinyl ureas are uniformly mixed；Again
1.5g fragrance and 87gRO water is added, is cooled down at room temperature after stirring evenly, obtains antiseptic；
(2) base material of the water intaking prick nonwoven cloth as wet sanitary napkins, is soaked in above-mentioned antiseptic 2-4 hours, when base material is in
Moistening obtains the wet sanitary napkins containing antiseptic without being packed when drop of liquid state.
Through wet sanitary napkins made from above-mentioned steps, include the antiseptic of base material and impregnated substrate；The base material be spun lacing without
Woven fabric；The antiseptic contains following components per 100g：2.5g pomegranate rind extracts, 3.5g glycerine, 1.5g Tween-20s, 3.0 third
Glycol, 1.0g diazonium imidazolidinyl ureas, 1.5g fragrance, 87gRO water.
It please check table 1, reference《GB15979-2002 disposable sanitary articles sanitary standards》Appendix C《Product bactericidal property,
Bacteriostasis property and stability test method》Sterilizing rate experiment, 5 minutes action time, the results showed that body surface are carried out to wet tissue
Common bacteria Escherichia coli ATCC25922, staphylococcus aureus ATCC6538, Candida albicans ATCC10321 are had
Effect inhibits.
Wet sanitary napkins sterilizing rate test result prepared by 1 embodiment 1 of table proportioning
| Bacterial species | Sterilizing rate % |
| Escherichia coli ATCC25922 | 89.5 |
| Staphylococcus aureus ATCC6538 | 90.0 |
| Candida albicans ATCC10321 | 78.1 |
Embodiment 2
A kind of antiseptic of the present embodiment contains following components per 100g：3.0g pomegranate rind extracts, 4.5g glycerine,
2.0g Tween-20s, 3.5g propylene glycol, 1.5g diazonium imidazolidinyl ureas, 1.5g fragrance, 84gRO water.The pomegranate rind extract is adopted
With the product of the Xi'an bio tech ltd Yuan Sen, product identification：YSS-003.
Above-mentioned antiseptic is applied to wet sanitary napkins preparation method, is included the following steps：
(1) it prepares and takes 3.0g pomegranate rind extracts per 100g antiseptics, be scattered in RO water, it is equal that the stirring of 4.5g glycerine is added
It is even, it is warming up to 30-40 DEG C；Then 2.0g Tween-20s, 3.5 propylene glycol is added, 1.5g diazonium imidazolidinyl ureas are uniformly mixed；Again
1.5g fragrance and 84gRO water is added, is cooled down at room temperature after stirring evenly, obtains antiseptic；
(2) base material of the water intaking prick nonwoven cloth as wet sanitary napkins, is soaked in above-mentioned antiseptic 2-4 hours, when base material is in
Moistening obtains the wet sanitary napkins containing antiseptic without being packed when drop of liquid state.
Through wet sanitary napkins made from above-mentioned steps, include the antiseptic of base material and impregnated substrate；The base material be spun lacing without
Woven fabric；The antiseptic contains following components per 100g：3.0g pomegranate rind extracts, 4.5g glycerine, 2.0g Tween-20s, 3.5g
Propylene glycol, 1.5g diazonium imidazolidinyl ureas, 1.5g fragrance, 84gRO water.
It please check table 2, reference《GB15979-2002 disposable sanitary articles sanitary standards》Appendix C《Product bactericidal property,
Bacteriostasis property and stability test method》Sterilizing rate experiment, 5 minutes action time, the results showed that body surface are carried out to wet tissue
Common bacteria Escherichia coli ATCC25922, staphylococcus aureus ATCC6538, Candida albicans ATCC10321 are had
Effect inhibits.
Wet sanitary napkins sterilizing rate test result prepared by 2 embodiment 2 of table proportioning
| Bacterial species | Sterilizing rate % |
| Escherichia coli ATCC25922 | 90.2 |
| Staphylococcus aureus ATCC6538 | 91.5 |
| Candida albicans ATCC10321 | 81.3 |
The above, only present pre-ferred embodiments, therefore cannot limit the scope of implementation of the present invention according to this, i.e., according to
Equivalent changes and modifications made by the scope of the claims of the present invention and description all should still belong in the range of the present invention covers.
Claims (4)
1. a kind of antiseptic, it is characterised in that：Contain following components per 100g：2.0-3.0g pomegranate rind extract, 3.0-5.0g
Glycerine, 1.5-2.0g Tween-20s, 3.0-5.0g propylene glycol, 1.0-1.5g diazonium imidazolidinyl ureas, qs Fragrance, remaining is RO
Water.
2. a kind of wet sanitary napkins antiseptic according to claim 1, it is characterised in that：Contain 1.0-1.5g perfume per 100g
Material.
3. a kind of wet sanitary napkins preparation method using antiseptic described in claim 1, it is characterised in that：Include the following steps：
(1) it prepares and takes 2.0-3.0g pomegranate rind extracts per 100g antiseptics, be scattered in RO water, 3.0-5.0g glycerine is added and stirs
It mixes uniformly, is warming up to 30-40 DEG C；Then 1.5-2.0g Tween-20s, 3.0-5.0g propylene glycol and 1.0-1.5g diazonium imidazoles is added
Ureine is uniformly mixed；1.0-1.5g fragrance is added, adds RO water to 100g, is cooled down at room temperature after stirring evenly, resisted
Microbial inoculum；
(2) base material of the water intaking prick nonwoven cloth as wet sanitary napkins, is soaked in above-mentioned antiseptic 2-4 hours, when base material is in moistening
Without being packed when drop of liquid state, the wet sanitary napkins containing antiseptic are obtained.
4. a kind of wet sanitary napkins, it is characterised in that：Include antiseptic as described in claim 1~2 and is impregnated with the antiseptic
Spunlace non-woven cloth base material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710523759.1A CN108295099A (en) | 2017-06-30 | 2017-06-30 | A kind of antiseptic and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710523759.1A CN108295099A (en) | 2017-06-30 | 2017-06-30 | A kind of antiseptic and its application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108295099A true CN108295099A (en) | 2018-07-20 |
Family
ID=62872595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710523759.1A Pending CN108295099A (en) | 2017-06-30 | 2017-06-30 | A kind of antiseptic and its application |
Country Status (1)
| Country | Link |
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| CN (1) | CN108295099A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110343471A (en) * | 2019-07-12 | 2019-10-18 | 杭州厚瑞科技有限公司 | A kind of medical instrument production line profession glue and preparation method thereof |
| CN110578250A (en) * | 2019-10-29 | 2019-12-17 | 江苏金荣泰新材料科技有限公司 | Antibacterial agent for nonwoven fabric |
| CN111494241A (en) * | 2020-06-01 | 2020-08-07 | 湖北洁世达环保科技有限公司 | Soft moisturizing liquid for paper towels |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2159113C1 (en) * | 2000-02-28 | 2000-11-20 | Шамама Идрис кызы Гурбанова | Agent with antiinflammatory, antiseptic, and regenerating activity |
| CN105064011A (en) * | 2015-09-09 | 2015-11-18 | 太原理工大学 | Method for performing antibiotic finishing on cotton fabric by use of granatum extract |
| CN106691892A (en) * | 2017-01-25 | 2017-05-24 | 江苏诺兴生物科技有限公司 | Antibacterial wet tissue and preparation method thereof |
-
2017
- 2017-06-30 CN CN201710523759.1A patent/CN108295099A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2159113C1 (en) * | 2000-02-28 | 2000-11-20 | Шамама Идрис кызы Гурбанова | Agent with antiinflammatory, antiseptic, and regenerating activity |
| CN105064011A (en) * | 2015-09-09 | 2015-11-18 | 太原理工大学 | Method for performing antibiotic finishing on cotton fabric by use of granatum extract |
| CN106691892A (en) * | 2017-01-25 | 2017-05-24 | 江苏诺兴生物科技有限公司 | Antibacterial wet tissue and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 王艳萍等: "《化妆品微生物学》", 31 January 2002, 中国轻工业出版社 * |
| 阚全程: "《医院药学高级教程》", 28 February 2015, 人民军医出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110343471A (en) * | 2019-07-12 | 2019-10-18 | 杭州厚瑞科技有限公司 | A kind of medical instrument production line profession glue and preparation method thereof |
| CN110578250A (en) * | 2019-10-29 | 2019-12-17 | 江苏金荣泰新材料科技有限公司 | Antibacterial agent for nonwoven fabric |
| CN111494241A (en) * | 2020-06-01 | 2020-08-07 | 湖北洁世达环保科技有限公司 | Soft moisturizing liquid for paper towels |
| CN111494241B (en) * | 2020-06-01 | 2023-03-24 | 湖北洁世达环保科技有限公司 | Soft moisturizing liquid for paper towels |
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Application publication date: 20180720 |