CN108290041A - 神经调节设备 - Google Patents

神经调节设备 Download PDF

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Publication number
CN108290041A
CN108290041A CN201680037057.6A CN201680037057A CN108290041A CN 108290041 A CN108290041 A CN 108290041A CN 201680037057 A CN201680037057 A CN 201680037057A CN 108290041 A CN108290041 A CN 108290041A
Authority
CN
China
Prior art keywords
signal
nerve
patient
neural activity
colitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680037057.6A
Other languages
English (en)
Chinese (zh)
Inventor
丹尼尔·约翰·楚
沃尔特·雅各布·德荣格
汉斯·雅各布·克里斯托弗·法姆
索那尔·帕特尔
奥乐夫·威尔廷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galvani Bioelectronics Co ltd
Academisch Medisch Centrum
Original Assignee
Galvani Bioelectronics Co ltd
Academic Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galvani Bioelectronics Co ltd, Academic Medical Center filed Critical Galvani Bioelectronics Co ltd
Publication of CN108290041A publication Critical patent/CN108290041A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680037057.6A 2015-04-24 2016-04-22 神经调节设备 Pending CN108290041A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562152119P 2015-04-24 2015-04-24
US62/152,119 2015-04-24
PCT/IB2016/052307 WO2016170510A1 (en) 2015-04-24 2016-04-22 Neuromodulation device

Publications (1)

Publication Number Publication Date
CN108290041A true CN108290041A (zh) 2018-07-17

Family

ID=55963419

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680037057.6A Pending CN108290041A (zh) 2015-04-24 2016-04-22 神经调节设备

Country Status (11)

Country Link
US (2) US10974041B2 (https=)
EP (2) EP3285856A1 (https=)
JP (1) JP2018514354A (https=)
KR (1) KR20180040516A (https=)
CN (1) CN108290041A (https=)
AU (1) AU2016252497A1 (https=)
BR (1) BR112017022941A2 (https=)
CA (1) CA2983652A1 (https=)
MA (1) MA41950A (https=)
RU (1) RU2017140776A (https=)
WO (1) WO2016170510A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113197587A (zh) * 2021-04-26 2021-08-03 中国科学院深圳先进技术研究院 一种用于迷走神经刺激和电生理检测的装置及植入方法
CN114177472A (zh) * 2021-11-30 2022-03-15 中国人民解放军总医院第四医学中心 一种应用于下肢假肢的植入式电刺激感知反馈系统

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US20150111918A1 (en) 2012-03-08 2015-04-23 Medtronic Ardian Luxembourg S.a.r.l Immune system neuromodulation and associated systems and methods
EP3226795B1 (en) 2014-12-03 2020-08-26 Metavention, Inc. Systems for modulating nerves or other tissue
WO2016197039A1 (en) * 2015-06-05 2016-12-08 The Johns Hopkins University Method and device for sacral nerve stimulation
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
ES2893847T3 (es) 2016-07-07 2022-02-10 Univ California Implantes que usan retrodispersión ultrasónica para detectar señales electrofisiológicas
WO2019122906A1 (en) 2017-12-20 2019-06-27 Galvani Bioelectronics Limited Treatment of acute medical conditions
WO2019122907A1 (en) 2017-12-20 2019-06-27 Galvani Bioelectronics Limited Treatment of acute medical conditions
US11446496B2 (en) 2017-12-20 2022-09-20 Galvani Bioelectronics Limited Treatment of disorders associated with inflammation
WO2019122903A2 (en) * 2017-12-20 2019-06-27 Galvani Bioelectronics Limited Stimulation of a nerve supplying the spleen
WO2019122904A1 (en) * 2017-12-20 2019-06-27 Galvani Bioelectronics Limited Treatment of inflammatory disorders
IL312444B2 (en) 2018-04-19 2025-05-01 Iota Biosciences Inc Implants that use ultrasonic communication to regulate splenic neural activity
CN118436321A (zh) 2018-04-19 2024-08-06 艾奧塔生物科技公司 使用用于神经感测和刺激的超声通信的植入物
US10974079B2 (en) * 2018-08-29 2021-04-13 General Electric Company Neuromodulation techniques
BR112021003792A2 (pt) 2018-08-29 2021-05-18 Iota Biosciences, Inc. dispositivo de neuromodulação em circuito fechado implantável, sistemas e métodos de uso
WO2020128790A1 (en) * 2018-12-20 2020-06-25 Galvani Bioelectronics Limited Neurostimulation device for blocking blood flow between electrodes
EP3986532A1 (en) * 2019-06-19 2022-04-27 Galvani Bioelectronics Limited System for the treatment of disorders associated with inflammation
WO2020254798A1 (en) * 2019-06-19 2020-12-24 Galvani Bioelectronics Limited Stimulation of a nerve supplying the spleen
US20220249840A1 (en) * 2019-06-19 2022-08-11 Galvani Bioelectronics Limited Treatment of Acute Medical Conditions
MX2022004584A (es) 2019-10-17 2022-09-26 Iota Biosciences Inc Dispositivos y métodos para modular la actividad del sistema inmunitario en un paciente con cáncer y tratamiento del cáncer.
WO2021207161A1 (en) * 2020-04-09 2021-10-14 General Electric Company Non-invasive focused ultrasound neuromodulation to treat physiological conditions
WO2022122833A1 (en) * 2020-12-09 2022-06-16 Galvani Bioelectronics Limited Physiological effects of activation of the alox15 pathway
WO2023017253A1 (en) * 2021-08-10 2023-02-16 Galvani Bioelectronics Limited Neuromodulation device
KR20230078121A (ko) * 2021-11-26 2023-06-02 주식회사 뉴라이브 동물용 미주신경 자극장치
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders

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US20050075702A1 (en) * 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator
US20050075701A1 (en) * 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for attenuating an immune response
US20060116736A1 (en) * 2001-07-23 2006-06-01 Dilorenzo Daniel J Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity
JP2008525102A (ja) * 2004-12-27 2008-07-17 ノース ショア−ロング アイランド ジューウィッシュ リサーチ インスティテュート 電気的な迷走神経刺激による炎症性障害の処置
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
WO2013124541A1 (en) * 2012-02-24 2013-08-29 Nokia Corporation Method and apparatus for dynamic server|client controlled connectivity logic
CN103415319A (zh) * 2010-12-28 2013-11-27 西比姆公司 用于患者的交感再平衡的方法
CN103619405A (zh) * 2011-05-09 2014-03-05 赛博恩特医疗器械公司 用于治疗慢性炎症的胆碱能抗炎通路的单个脉冲激活
US20140222124A1 (en) * 2006-02-10 2014-08-07 ElectroCore, LLC Methods and apparatus for treating anaphylaxis using electrical modulation
WO2014153223A1 (en) * 2013-03-14 2014-09-25 Perryman Laura Tyler Treating inflammation, chronic pain and other disorders with neuromodulation
JP2015502820A (ja) * 2011-12-09 2015-01-29 メタベンション インコーポレイテッド 肝臓系の治療的な神経調節

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US7389145B2 (en) 2001-02-20 2008-06-17 Case Western Reserve University Systems and methods for reversibly blocking nerve activity
US8214047B2 (en) * 2004-09-27 2012-07-03 Advanced Neuromodulation Systems, Inc. Method of using spinal cord stimulation to treat gastrointestinal and/or eating disorders or conditions
AU2006315829B2 (en) * 2005-11-10 2011-01-27 ElectroCore, LLC. Electrical stimulation treatment of bronchial constriction
US9539425B2 (en) * 2006-10-13 2017-01-10 Intelect Medical, Inc. Systems and methods for treating medical conditions by stimulation of medial thalamic region
JPWO2008096730A1 (ja) * 2007-02-09 2010-05-20 国立大学法人名古屋大学 抗炎症剤及びその用途
EP2709717B1 (en) 2011-05-19 2020-02-26 Neuros Medical, Inc. Cuff electrode and generator for reversible electrical nerve block
WO2013134541A2 (en) * 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Gastrointestinal neuromodulation and associated systems and methods

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060116736A1 (en) * 2001-07-23 2006-06-01 Dilorenzo Daniel J Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity
US20050075702A1 (en) * 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator
US20050075701A1 (en) * 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for attenuating an immune response
JP2008525102A (ja) * 2004-12-27 2008-07-17 ノース ショア−ロング アイランド ジューウィッシュ リサーチ インスティテュート 電気的な迷走神経刺激による炎症性障害の処置
US20140222124A1 (en) * 2006-02-10 2014-08-07 ElectroCore, LLC Methods and apparatus for treating anaphylaxis using electrical modulation
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
CN103415319A (zh) * 2010-12-28 2013-11-27 西比姆公司 用于患者的交感再平衡的方法
CN103619405A (zh) * 2011-05-09 2014-03-05 赛博恩特医疗器械公司 用于治疗慢性炎症的胆碱能抗炎通路的单个脉冲激活
JP2015502820A (ja) * 2011-12-09 2015-01-29 メタベンション インコーポレイテッド 肝臓系の治療的な神経調節
WO2013124541A1 (en) * 2012-02-24 2013-08-29 Nokia Corporation Method and apparatus for dynamic server|client controlled connectivity logic
WO2014153223A1 (en) * 2013-03-14 2014-09-25 Perryman Laura Tyler Treating inflammation, chronic pain and other disorders with neuromodulation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113197587A (zh) * 2021-04-26 2021-08-03 中国科学院深圳先进技术研究院 一种用于迷走神经刺激和电生理检测的装置及植入方法
CN114177472A (zh) * 2021-11-30 2022-03-15 中国人民解放军总医院第四医学中心 一种应用于下肢假肢的植入式电刺激感知反馈系统

Also Published As

Publication number Publication date
RU2017140776A (ru) 2019-05-24
WO2016170510A1 (en) 2016-10-27
CA2983652A1 (en) 2016-10-27
US20210393949A1 (en) 2021-12-23
AU2016252497A1 (en) 2017-11-09
MA41950A (fr) 2018-02-28
EP3285856A1 (en) 2018-02-28
US10974041B2 (en) 2021-04-13
BR112017022941A2 (pt) 2018-07-17
KR20180040516A (ko) 2018-04-20
US20180117319A1 (en) 2018-05-03
JP2018514354A (ja) 2018-06-07
EP3950049A1 (en) 2022-02-09

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Application publication date: 20180717