CN108267329A - A kind of sampling device of histopathology sample - Google Patents
A kind of sampling device of histopathology sample Download PDFInfo
- Publication number
- CN108267329A CN108267329A CN201810230799.1A CN201810230799A CN108267329A CN 108267329 A CN108267329 A CN 108267329A CN 201810230799 A CN201810230799 A CN 201810230799A CN 108267329 A CN108267329 A CN 108267329A
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- box
- sample
- puncture tube
- riker mount
- waxdip
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- 238000005070 sampling Methods 0.000 title claims abstract description 34
- 230000018044 dehydration Effects 0.000 claims abstract description 37
- 238000006297 dehydration reaction Methods 0.000 claims abstract description 37
- 239000000463 material Substances 0.000 claims abstract description 7
- 230000008014 freezing Effects 0.000 claims description 6
- 238000007710 freezing Methods 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 4
- 238000002386 leaching Methods 0.000 claims description 2
- 238000009738 saturating Methods 0.000 claims 1
- 238000012545 processing Methods 0.000 abstract description 4
- 238000001514 detection method Methods 0.000 abstract description 2
- 208000005156 Dehydration Diseases 0.000 description 30
- 238000003745 diagnosis Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000010827 pathological analysis Methods 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 240000005373 Panax quinquefolius Species 0.000 description 1
- 208000026062 Tissue disease Diseases 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/42—Low-temperature sample treatment, e.g. cryofixation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The present invention provides a kind of sampling device of histopathology sample, including sampling platform, lancing system, Riker mount, dehydration waxdip box and control system.The sampling platform includes Riker mount microscope carrier and waxdip box microscope carrier, and is respectively equipped with the driving device of the outside horizontal transport of both drivings.The lancing system includes pipe support and puncture tube.The Riker mount is placed on Riker mount microscope carrier, and including box body and box cover, box body is built-in sample to be measured, and each face of box body and the equal surface of box cover are provided with several thief holes.The dehydration waxdip box is placed on waxdip box microscope carrier, and box body side is provided with several sample holes and regularly arranged.The control system includes supply unit and controller.The degree of automation of the present invention is higher, disposably it can obtain sample from multiple positions of histopathology sample by more root puncture pipes and be sent into dehydration waxdip box and carry out subsequent processing, substantially increase materials speed, and the detection and analysis position of sample is more comprehensive, improves the objectivity and accuracy of analysis.
Description
Technical field
The present invention relates to the field of medical instrument technology, and in particular to a kind of sampling device of histopathology sample.
Background technology
Histopathology sample（Hereinafter referred to as sample）Materials, refer to acquired in the tissue of monoblock or bulk it is representational
Part makes pathological section, is a very important link in histopathogenic diagnosis for histopathogenic diagnosis.For big
Can the histopathology sample of block collect representational diseased region and be presented to diagnosis extremely pass of the diagnostician for disease
It is important.The conventional method used at present is first to fix the sample of bulk with neutral formalin, and the set time usually requires 24-
It 72 hours, is adjusted according to factors such as the sizes, quality, temperature of sample（The processing time of entire sample is generally in 3-5 work
Make day, it is seen that the length of set time is very important to the influence the time required to completing pathological diagnosis）, sample is bigger, fills
Divide the fixed required time longer.After fully fixing, there may be the part of diagnostic value by pathologist acquisition for making
Make pathological section.If not collecting the tissue of diagnostic value for the first time, need to carry out second or even third time acquisition group
It knits, the selection at this acquisition position has apparent empirical and subjectivity.
Time is life, even more so for patient, therefore, in order to shorten the sample disposal required time,
It provides accurate pathological diagnosis to patient as early as possible to report, it is necessary to improve the materials link of sample, make fully to fix required
Time shortens, and can comprehensively react the scheme of disease event.
The disclosed patent application of our company（Patent publication No. CN107576558A）Disclose a kind of tissue disease for exempting from embedding
Manage sample dehydration waxdip box, the dehydration waxdip box helped to realize after tissue specimen is put into fixed, washing, dehydration, it is transparent and
These steps of waxdip are carried out continuously without compartment of terrain, and eliminate embedding step, and the present invention will be by the structure of dehydration waxdip box
Feature, the sampling device that optimization sample is handled before fixing step.
Invention content
The present invention for it is above-mentioned middle the technical issues of, provide it is a kind of can shorten the sample set time, comprehensively reflection disease feelings
The histopathology specimen sampling device of condition.
To solve the technical issues of above-mentioned middle, the technical solution adopted in the present invention is：
A kind of sampling device of histopathology sample, which is characterized in that including：
- sampling platform：Including Riker mount microscope carrier and waxdip box microscope carrier, and it is respectively equipped with the sample of the outside horizontal transport of both drivings
Box stage driving and waxdip box stage driving；
- lancing system：Including pipe support and puncture tube, pipe support is fixedly connected with the sampling platform, and the pipe support is in the sampling platform
Top is equipped with sliding rail, more piece pipes of the puncture tube for single pipe or side by side, the puncture tube and the sliding rail vertical connection and edge
Sliding rail moves horizontally, and is equipped with and drives the puncture tube horizontal drive apparatus that the puncture tube moves horizontally；The nozzle of the puncture tube
Downward, the pipe flange of nozzle is in featheredge, the tube core moved along pipe shaft direction is equipped in the puncture tube, and be equipped with and drive tube core same
The tube core driving device of Shi Yidong；
- Riker mount：It is placed on the Riker mount microscope carrier, including the box body and box cover being square, box body is built-in mark to be measured
This, each face of the box body and the equal surface of box cover are provided with several thief holes, and the thief hole is regularly arranged and size is identical and can
Accommodate the puncture tube tube body enter, the spacing in adjacent samples hole is consistent, for the puncture tube by the thief hole into
Enter in Riker mount and draw materials to sample；
- dehydration waxdip box：It is placed on the waxdip box microscope carrier, the box body side of the dehydration waxdip box is provided with several sample holes simultaneously
Regularly arranged, sample holes can accommodate the puncture tube and enter, and are inserted into dehydration waxdip box as the puncture tube and place what is taken
The channel of sample；
- control system：Including supply unit and controller, the controller for control above-mentioned Riker mount stage driving,
The work of waxdip box stage driving, puncture tube horizontal drive apparatus, puncture tube vertical drive and tube core driving device,
And set control button.
The sampling platform surface is equipped with cleaning system between Riker mount microscope carrier and waxdip box microscope carrier, including vertical rinse bath and
Core pulling and filling system.
The Riker mount microscope carrier is equipped with surface-cooler, and start and stop and temperature is controlled to adjust by the controller, for making
Sample in Riker mount keeps freezing state.
When the puncture tube is more pipes side by side, expansion bracket is connected between each pipe, and be equipped with expansion bracket driving device,
It is controlled by the controller, the adjacent tube spacing that punctures is according to the pitch of holes of the thief hole for the Riker mount for intending entering or dehydration waxdip box
The pitchs of holes of sample holes be adjusted by preset parameter, puncture tube is made smoothly to enter in Riker mount or dehydration waxdip box.
The pipe shaft back side of the puncture tube is equipped with watch window, and the pipe support is additionally provided with knife rest and is equipped with cutoff tool, institute
The edge of a knife for stating cutoff tool is vertical with the pipe shaft of the puncture tube, and the edge of a knife that the watch window can accommodate the cutoff tool enters pipe
Interior, the quantity of the cutoff tool is consistent with the quantity of the puncture tube, is controlled equipped with cut-out driving device for cutter and by controller, uses
In the spacing and advance and retreat of control cutoff tool.
The Riker mount is transparent or translucent, and the thief hole is identical with the pipe shaft shape of the puncture tube.
The controller is equipped in the sampling platform surface and expands interface, is connect including USB interface, communication interface and network
Mouthful.
The supply unit includes battery and externally fed connecting line.
The sampling device of the histopathology sample of the present invention, the degree of automation is higher, can be disposable by more root puncture pipes
It obtains sample from multiple positions of histopathology sample and is sent into dehydration waxdip box and carry out subsequent processing, substantially reducing needs
The tissue volume to be fixed, so as to shorten abundant fixed required time, and the detection and analysis position of sample is more comprehensive,
While quality is ensured, the time required to shortening pathological diagnosis.
Description of the drawings
Fig. 1 is the overall structure diagram of apparatus of the present invention；
Fig. 2 is the expansion bracket structure diagram of the puncture tube of the present invention；
Fig. 3 is the puncture tube back of the present invention and cutter frame structure schematic diagram.
It illustrates：1- Riker mounts microscope carrier, 2- waxdip boxes microscope carrier, 3- Riker mounts, 4- thief holes, 5- sample holes, 6- dehydrations
Waxdip box, 7- pipe supports, 8- puncture tubes, 9- tube cores, the vertical rinse baths of 10-, 11- surface-coolers, 12- scissor type telescopics frame, 13-
Watch window, 14- cutoff tools.
Specific embodiment
Below in conjunction with the accompanying drawings, the present invention is further described.
A kind of sampling device of histopathology sample as shown in Figure 1, including sampling platform, lancing system, Riker mount（3）, it is de-
Water logging wax box（6）With control system etc..
Sampling platform includes Riker mount microscope carrier（1）, waxdip box microscope carrier（2）And rinsing table, wherein Riker mount microscope carrier（1）, waxdip
Box microscope carrier（2）It is respectively equipped with the Riker mount microscope carrier of the outside horizontal transport of both drivings（1）Driving device and waxdip box microscope carrier（2）It drives
Dynamic device, Riker mount microscope carrier（1）With waxdip box microscope carrier（2）Several Riker mounts can be sequentially placed（3）With dehydration waxdip box（6）.Together
When Riker mount microscope carrier（1）Equipped with surface-cooler（11）, and start and stop and temperature is controlled to adjust by the controller, for making sample
Box（3）Interior sample keeps freezing state, and histopathology sample will be housed（Histopathology sample can be fresh or through fixation
Liquid is tentatively fixed）Riker mount（3）It is positioned on freezing stage, histopathology sample temperature is made to be down between 0 degree to -20 DEG C,
It is maintained at freezing state.Riker mount microscope carrier（1）With waxdip box microscope carrier（2）Between be equipped with cleaning system, including vertical rinse bath（10）
And core pulling and filling system, puncture tube（8）Enter the vertical rinse bath after completing step action（10）It is cleaned.
Lancing system includes pipe support（7）And puncture tube（8）, pipe support（7）It is fixedly connected with sampling platform, while pipe support（7）In
Sliding rail, puncture tube are equipped with above the sampling platform（8）For 5 pipes side by side, the puncture tube（8）With the sliding rail vertical connection simultaneously
It is moved horizontally along sliding rail, and is equipped with and drives the puncture tube（8）The puncture tube moved horizontally（8）Horizontal drive apparatus.Each puncture tube
（8）Nozzle downward, the pipe flange of nozzle is in sharp featheredge, the puncture tube（8）It is interior equipped with the pipe moved along pipe shaft direction
Core（9）, tube core（9）It is in the form of a column, and is equipped with and drives tube core（9）Mobile tube core simultaneously（9）Driving device.As shown in Fig. 2, it respectively wears
Thorn pipe（8）Between be connected with scissor type telescopic frame（12）, and equipped with expansion bracket driving device, by the controller control in control system
System, adjacent puncture tube（8）Spacing is according to the Riker mount for intending entering（3）Thief hole（4）Pitch of holes or dehydration waxdip box（6）'s
Sample holes（5）Pitch of holes be adjusted by preset parameter, make puncture tube（8）Smoothly enter Riker mount（3）Or dehydration leaching
Wax box（6）In.As shown in figure 3, each puncture tube（8）Pipe shaft back side be equipped with watch window（13）, on the one hand effect is to be used for
Observation punctures the length of gained tissue specimen, so as to determine the dehydration waxdip box for needing to be used for receiving tissue specimen（6）Quantity；
On the other hand it is as cutoff tool（14）Cut-out tissue entrance.Pipe support（7）It is additionally provided with knife rest and cutoff tool is installed（14）,
The cutoff tool（14）The edge of a knife and the puncture tube（8）Pipe shaft it is vertical, the watch window（13）The cut-out can be accommodated
Knife（14）The edge of a knife enter in pipe the sample sampled in pipe is cut off after enter the dehydration waxdip box（6）In, it is described
Cutoff tool（14）Quantity and the puncture tube（8）Quantity it is consistent, equipped with cutoff tool（14）Driving device and by controller control
System, for controlling cutoff tool（14）Spacing and advance and retreat.Work as cutoff tool（14）Into corresponding watch window（13）When, it will be puncture
Pipe（8）Interior tissue is completely cut through.In the case where needle core retreats, puncture needle is from Riker mount（3）The hole of side punctures sample, obtains
Obtain being organized in every root puncture needle tubing for bar shaped.In puncture tube（8）After puncture obtains tissue specimen, by cutoff tool（14）From each
Watch window（13）It is inserted into, acquired tissue specimen item is cut into and watch window（13）The consistent trifle of spacing.It is for example, de-
Water logging wax box（6）It is placed side by side that the tissue specimen that 5 length are 1cm can be accommodated, and puncture the group that 5 length of gained are 5cm
Knit sample, the adjacent watch window of puncture tube（13）Spacing is 1cm, and each tissue is thus cut into the trifle of 1cm long, phase
The trifle of side by side 5 adjacent 1cm long simultaneously drains into a dehydration waxdip box（6）In.
Riker mount（3）It is placed in Riker mount microscope carrier（1）On, including the box body and box cover being square, box body is built-in have it is to be measured
Sample, box body and box cover are transparent or translucent, are observed convenient for the situation to sample in box.Each face of box body and box cover are equal
Surface is provided with several thief holes（4）, the thief hole（4）Regularly arranged 5 and size it is identical and the puncture tube can be accommodated
（8）Tube body enter, adjacent samples hole（4）Spacing it is consistent, for puncture tube（8）Pass through the thief hole（4）Into sample
Box（3）In draw materials to sample.
It is dehydrated waxdip box（6）It is placed in waxdip box microscope carrier（2）On, and uniformly it is placed with multiple dehydration waxdip boxes（6）.The dehydration
Waxdip box（6）Box body side be provided with 5 sample holes（5）And regularly arranged, sample holes（5）The puncture tube can be accommodated（8）Into
Enter, for the puncture tube（8）Insertion.
Control system includes supply unit and controller, and controller is used to control above-mentioned Riker mount microscope carrier（1）Driving device,
Waxdip box microscope carrier（2）Driving device, puncture tube（8）Horizontal drive apparatus, tube core（9）Driving device, cutoff tool（14）Driving dress
It puts, the work of expansion bracket driving device, and sets control button.Meanwhile supply unit includes battery and externally fed connecting line, keeps away
Exempt from device to power off suddenly at work.Controller is equipped in the sampling platform surface and expands interface, is connect including USB interface, communication
Mouthful and network interface, for carry out network communication connection and to display device, camera shooting harvester, storage device etc. is related fills
Connection is put, further enriches the function of device.
During work, Riker mount microscope carrier（1）, waxdip box microscope carrier（2）It is equipped with corresponding Riker mount respectively（3）With dehydration waxdip box
（6）, sample is placed in Riker mount（3）In, and pass through surface-cooler（11）Keep freezing state.Puncture tube（8）It is moved to sample
Box（3）Top, each puncture tube（8）Between distance according to preset parameter adjustment to and Riker mount（3）Thief hole（4）Spacing one
It causes, each puncture needle rises, puncture tube（8）Smoothly enter Riker mount（3）And it is pierced into sample, while the sample tissue at pierced position
Into in pipe, then puncture tube（8）Rise with the sample in pipe, leave Riker mount（3）.Passed through manually or by vision system
Watch window（13）Interior length of tissue is dehydrated waxdip box so as to determine to receive needed for sample（6）Quantity.In puncture tube（8）
After puncture obtains tissue specimen, by cutoff tool from each watch window（13）Be inserted into, by acquired tissue specimen item be cut into
Watch window（13）The consistent trifle of spacing.Then puncture tube（8）It is moved to dehydration waxdip box（6）Top, each puncture tube（8）Between
Distance according to preset parameter adjustment to be dehydrated waxdip box（6）Sample holes（5）Spacing is consistent, puncture tube（8）Smoothly into
Enter to be dehydrated waxdip box（6）In, each puncture needle moves down, into dehydration waxdip box（6）In after, be directly inserted into bosom, Ran Houguan
Core（9）Push away tissue specimen, puncture tube on one side（8）It retreats on one side, by row's puncture tube（8）Interior farthest section tissue specimen is put into
One dehydration waxdip box（6）In.
Then puncture tube（8）It is lifted off the dehydration waxdip box（6）, waxdip box microscope carrier（2）Start, it is each to be dehydrated waxdip box
（6）Forward, latter dehydration waxdip box（6）Reach puncture tube（8）Lower section.If puncture tube（8）Interior tissue specimen length is more than one
A dehydration waxdip box（6）Receiving limit, then puncture tube（8）It is inserted into next dehydration waxdip box（6）, discharge in the same way
Tissue specimen so carries out being put into dehydration waxdip box to by samples all in puncture tube successively（6）In.It respectively will be equipped with sample
It is dehydrated waxdip box（6）Carry out subsequent processing detection program.It, then can be by only solid if fixed sample not yet abundant before materials
The fixed gained that punctures is organized, so as to shorten the time needed for sample disposal.Puncture tube（8）Into vertical rinse bath（10）Middle cleaning.
After the sample disposal for completing a patient, it is marked to identify, then Riker mount microscope carrier（1）Driving device and waxdip box
Microscope carrier（2）The Riker mount of the patient and dehydration waxdip box are moved to designated position by driving device, and manually by Sheng, there are one patients
The Riker mount of sample be positioned over Riker mount microscope carrier, the dehydration waxdip box for intending holding used in collected sample is positioned over waxdip box
Microscope carrier, then repeated work.
The above only expresses the preferred embodiment of the present invention, and description is more specific and in detail, but can not be because
This and be interpreted as the limitation to the scope of the claims of the present invention.It should be pointed out that for those of ordinary skill in the art,
Under the premise of not departing from present inventive concept, several deformations can also be made, improves and substitutes, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (8)
1. a kind of sampling device of histopathology sample, which is characterized in that including：
- sampling platform：Including Riker mount microscope carrier and waxdip box microscope carrier, and it is respectively equipped with the sample of the outside horizontal transport of both drivings
Box stage driving and waxdip box stage driving；
- lancing system：Including pipe support and puncture tube, pipe support is fixedly connected with the sampling platform, and the pipe support is in the sampling platform
Top is equipped with sliding rail, more piece pipes of the puncture tube for single pipe or side by side, the puncture tube and the sliding rail vertical connection and edge
Sliding rail moves horizontally, and is equipped with and drives the puncture tube horizontal drive apparatus that the puncture tube moves horizontally；The nozzle of the puncture tube
Downward, the pipe flange of nozzle is in featheredge, the tube core moved along pipe shaft direction is equipped in the puncture tube, and be equipped with and drive tube core same
The tube core driving device of Shi Yidong；
- Riker mount：It is placed on the Riker mount microscope carrier, including the box body and box cover being square, box body is built-in mark to be measured
This, each face of the box body and the equal surface of box cover are provided with several thief holes, and the thief hole is regularly arranged and size is identical and can
Accommodate the puncture tube tube body enter, the spacing in adjacent samples hole is consistent, for the puncture tube by the thief hole into
Enter in Riker mount and draw materials to sample；
- dehydration waxdip box：It is placed on the waxdip box microscope carrier, the box body side of the dehydration waxdip box is provided with several sample holes simultaneously
Regularly arranged, sample holes can accommodate the puncture tube and enter, and discharge taken sample to the dehydration leaching for the puncture tube
In wax box；
- control system：Including supply unit and controller, the controller for control above-mentioned Riker mount stage driving,
The work of waxdip box stage driving, puncture tube horizontal drive apparatus and tube core driving device, and set control button.
A kind of 2. sampling device of histopathology sample according to claim 1, which is characterized in that the sampling platform table
Face is equipped with cleaning system, including vertical rinse bath and core pulling and filling system between Riker mount microscope carrier and waxdip box microscope carrier.
A kind of 3. sampling device of histopathology sample according to claim 1, which is characterized in that the Riker mount microscope carrier
Start and stop and temperature is controlled to adjust equipped with surface-cooler, and by the controller, for the sample in Riker mount to be made to keep freezing
State.
4. the sampling device of a kind of histopathology sample according to claim 1, which is characterized in that the puncture tube is simultaneously
During the more pipes of row, expansion bracket is connected between each pipe, and be equipped with expansion bracket driving device, is controlled by the controller, it is adjacent
Tube spacing is punctured according to the pitch of holes of the pitch of holes of the thief hole for the Riker mount for intending entering or the sample holes for being dehydrated waxdip box to be passed through
Preset parameter is adjusted, and puncture tube is made smoothly to enter in Riker mount or dehydration waxdip box.
A kind of 5. sampling device of histopathology sample according to claim 1, which is characterized in that the pipe of the puncture tube
Side is carried on the body equipped with watch window, the pipe support is additionally provided with knife rest and is equipped with cutoff tool, and the edge of a knife of the cutoff tool is worn with described
Pierce pipe pipe shaft it is vertical, the edge of a knife that the watch window can accommodate the cutoff tool enters in pipe, the quantity of the cutoff tool with
The quantity of the puncture tube is consistent, driving device for cutter and is controlled equipped with cut-out by controller, for control the spacing of cutoff tool and
It retreats.
6. the sampling device of a kind of histopathology sample according to claim 1, which is characterized in that the Riker mount is in saturating
Bright or translucent, the thief hole is identical with the pipe shaft shape of the puncture tube.
7. the sampling device of a kind of histopathology sample according to claim 1, which is characterized in that the controller is in institute
It states sampling platform surface and is equipped with expansion interface, including USB interface, communication interface and network interface.
A kind of 8. sampling device of histopathology sample according to claim 1, which is characterized in that the supply unit packet
Include battery and externally fed connecting line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810230799.1A CN108267329A (en) | 2018-03-20 | 2018-03-20 | A kind of sampling device of histopathology sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810230799.1A CN108267329A (en) | 2018-03-20 | 2018-03-20 | A kind of sampling device of histopathology sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108267329A true CN108267329A (en) | 2018-07-10 |
Family
ID=62775364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810230799.1A Pending CN108267329A (en) | 2018-03-20 | 2018-03-20 | A kind of sampling device of histopathology sample |
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| Country | Link |
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| CN (1) | CN108267329A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110865018A (en) * | 2019-08-08 | 2020-03-06 | 上海交通大学医学院附属新华医院 | Sample post-processing system, device and method |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011013050A (en) * | 2009-06-30 | 2011-01-20 | Pathology Institute | Method for preparing biosample specimen |
| CN105372102A (en) * | 2015-07-14 | 2016-03-02 | 黄桂晓 | Medical examination puncture sample collecting and fixing device |
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| JP2011013050A (en) * | 2009-06-30 | 2011-01-20 | Pathology Institute | Method for preparing biosample specimen |
| CN105372102A (en) * | 2015-07-14 | 2016-03-02 | 黄桂晓 | Medical examination puncture sample collecting and fixing device |
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| CN110865018A (en) * | 2019-08-08 | 2020-03-06 | 上海交通大学医学院附属新华医院 | Sample post-processing system, device and method |
| CN110865018B (en) * | 2019-08-08 | 2023-03-28 | 上海交通大学医学院附属新华医院 | Sample post-processing system, device and method |
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