CN108265065A - 一种重组黄花蒿1类变应原蛋白及其应用 - Google Patents
一种重组黄花蒿1类变应原蛋白及其应用 Download PDFInfo
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- CN108265065A CN108265065A CN201711379683.6A CN201711379683A CN108265065A CN 108265065 A CN108265065 A CN 108265065A CN 201711379683 A CN201711379683 A CN 201711379683A CN 108265065 A CN108265065 A CN 108265065A
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- artemisia annua
- albumen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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- Biomedical Technology (AREA)
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- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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CN2016112705252 | 2016-12-31 | ||
CN201611270525 | 2016-12-31 |
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CN108265065A true CN108265065A (zh) | 2018-07-10 |
CN108265065B CN108265065B (zh) | 2021-04-27 |
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CN201711379683.6A Active CN108265065B (zh) | 2016-12-31 | 2017-12-20 | 一种重组黄花蒿1类变应原蛋白及其应用 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023125956A1 (zh) * | 2021-12-30 | 2023-07-06 | 江苏众红生物工程创药研究院有限公司 | 重组黄花蒿花粉i型变应原及其制备方法和应用 |
WO2023125958A1 (zh) * | 2021-12-30 | 2023-07-06 | 江苏众红生物工程创药研究院有限公司 | 重组艾蒿花粉i型变应原及其制备方法和应用 |
Citations (8)
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JP2008164523A (ja) * | 2006-12-28 | 2008-07-17 | Nippon Medical Soken:Kk | 唾液を利用したアレルギー診断薬 |
WO2010043675A1 (en) * | 2008-10-15 | 2010-04-22 | Alk-Abelló A/S | Pharmaceutical product for up-dosing of allergy vaccine |
CN101905022A (zh) * | 2009-06-08 | 2010-12-08 | 浙江我武生物科技有限公司 | 一种稳定的含有蒿属花粉变应原的药物组合物及其制备方法 |
CN102512673A (zh) * | 2011-12-21 | 2012-06-27 | 北京新华联协和药业有限责任公司 | 蒿属花粉变应原注射用疫苗及其制备方法 |
CN102552900A (zh) * | 2011-12-21 | 2012-07-11 | 北京新华联协和药业有限责任公司 | 蒿属花粉变应原疫苗及其制备方法和应用 |
CN103710368A (zh) * | 2013-12-30 | 2014-04-09 | 江苏众红生物工程创药研究院有限公司 | 哺乳动物细胞表达的人激肽释放酶和编码基因及其应用 |
US20160287696A1 (en) * | 2013-11-20 | 2016-10-06 | La Jolla Institute For Allergy And Immunology | Pan pollen immunogens and methods and uses for immune response modulation |
CN106967696A (zh) * | 2017-02-22 | 2017-07-21 | 杭州艾乐吉生物科技有限公司 | 一种蒿属植物花粉的过敏原及其应用 |
-
2017
- 2017-12-20 CN CN201711379683.6A patent/CN108265065B/zh active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008164523A (ja) * | 2006-12-28 | 2008-07-17 | Nippon Medical Soken:Kk | 唾液を利用したアレルギー診断薬 |
WO2010043675A1 (en) * | 2008-10-15 | 2010-04-22 | Alk-Abelló A/S | Pharmaceutical product for up-dosing of allergy vaccine |
CN101905022A (zh) * | 2009-06-08 | 2010-12-08 | 浙江我武生物科技有限公司 | 一种稳定的含有蒿属花粉变应原的药物组合物及其制备方法 |
CN102512673A (zh) * | 2011-12-21 | 2012-06-27 | 北京新华联协和药业有限责任公司 | 蒿属花粉变应原注射用疫苗及其制备方法 |
CN102552900A (zh) * | 2011-12-21 | 2012-07-11 | 北京新华联协和药业有限责任公司 | 蒿属花粉变应原疫苗及其制备方法和应用 |
US20160287696A1 (en) * | 2013-11-20 | 2016-10-06 | La Jolla Institute For Allergy And Immunology | Pan pollen immunogens and methods and uses for immune response modulation |
CN103710368A (zh) * | 2013-12-30 | 2014-04-09 | 江苏众红生物工程创药研究院有限公司 | 哺乳动物细胞表达的人激肽释放酶和编码基因及其应用 |
CN106967696A (zh) * | 2017-02-22 | 2017-07-21 | 杭州艾乐吉生物科技有限公司 | 一种蒿属植物花粉的过敏原及其应用 |
Non-Patent Citations (5)
Title |
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DU,J.等: "Artemisia vulgaris Art v1 mRNA,partial cds", 《GENBANK DATABASE》 * |
GADERMAIER,G.等: "Artemisia annua major pollen allergen Art v 1-like protein mRNA,partial cds", 《GENBANK DATABASE》 * |
MARC SIEGERT等: "Expression of the major mugwort pollen allergen Art v 1 in tobacco plants and cell cultures: problems and perspectives for allergen production in plants", 《PLANT CELL REP》 * |
李兴永等: "大籽蒿花粉过敏原的分离、鉴定与纯化", 《中国免疫学杂志》 * |
李志良等: "新疆黄花蒿花粉变应原的分离及纯化", 《新疆医学院学报》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023125956A1 (zh) * | 2021-12-30 | 2023-07-06 | 江苏众红生物工程创药研究院有限公司 | 重组黄花蒿花粉i型变应原及其制备方法和应用 |
WO2023125958A1 (zh) * | 2021-12-30 | 2023-07-06 | 江苏众红生物工程创药研究院有限公司 | 重组艾蒿花粉i型变应原及其制备方法和应用 |
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Address after: 213125 No. 518 Yunhe Road, Xinbei District, Changzhou City, Jiangsu Province Applicant after: ZonHon Biopharma Institute Inc. Applicant after: Jiangsu Jingsen Biomedical New Materials Technology Co., Ltd. Address before: 213125 No. 518 Yunhe Road, Xinbei District, Changzhou City, Jiangsu Province Applicant before: ZonHon Biopharma Institute Inc. Applicant before: Changzhou Gensun Institute of Biomedicine Co., Ltd. |
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