CN108159359A - Treat the prescription of the stagnation of QI-blood proliferation of mammary gland - Google Patents
Treat the prescription of the stagnation of QI-blood proliferation of mammary gland Download PDFInfo
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- CN108159359A CN108159359A CN201810182935.4A CN201810182935A CN108159359A CN 108159359 A CN108159359 A CN 108159359A CN 201810182935 A CN201810182935 A CN 201810182935A CN 108159359 A CN108159359 A CN 108159359A
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- Prior art keywords
- mammary gland
- blood
- prescription
- stagnation
- proliferation
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
Abstract
The invention belongs to Chinese pharmacology fields, relate in particular to the prescription of the treatment stagnation of QI-blood proliferation of mammary gland, are made of peach kernel, safflower, army processed, ground beetle, RADIX CURCUMAE.It can reach promoting blood circulation and removing blood stasis by using technical solution disclosed by the invention, dredge the effect of newborn network.So as to effectively treat the stagnation of QI-blood proliferation of mammary gland.
Description
Technical field
The invention belongs to Chinese pharmacology fields, more particularly to treat the Chinese medicinal formulae field of the proliferation of mammary gland, relate in particular to
Treat the prescription of the stagnation of QI-blood proliferation of mammary gland.
Background technology
Mammary gland disease is a kind of common disease, frequently-occurring disease, largely endangers women's physical and mental health, can clinically be divided into mammary gland
Inflammation, the proliferation of mammary gland, mammary gland fibroma, galactoncus, five major class of breast cancer.Its pathogenic factor is more complicated, such as treats not in time
Or malpractice, time have been grown and may ferment serious change and even result in life danger.Therefore mammary gland disease is particularly
The treatment of early stage mammary gland disease is particularly important.
Clinically most common pathologic stage is the proliferation of mammary gland in mammary gland disease.The common treatment side of the proliferation of mammary gland at present
Formula include based on hormone medicine, Operand, vitamin A, B6, E auxiliary western medicine method and by extracing mammary gland
Fibromatous therapeutic method of surgery；Simultaneously because the generation of cyclomastopathy often with it is tired, life is irregular, nervous,
Pressure is overweight related, therefore can relieve pressure, and calm down the psychotherapy of phychology also has centainly in the treatment of cyclomastopathy
Application.
Since the drug therapy of doctor trained in Western medicine easily generates dependence, and its operative treatment mode forms significantly female body
Injury, therefore, relatively mild Chinese traditional treatment mode increasingly attracts attention at present.
CN102886018A discloses a kind of Chinese medicine preparation for treating the proliferation of mammary gland, wherein specific disclosure is matched by following weight
Made of the raw material of ratio：Pangolin 10-15, kelp 10-15, RADIX CURCUMAE 10-15, rheum officinale 15-20, frankincense 15-20, dandelion
15-20, Fructus Liquidambaris 15-20, oldenlandia diffusa 10-15, selfheal 10-15, seaweed 20-25, tangerine seed 15-20, curcuma zedoary 15-20,
Trigone 20-25, Radix Glycyrrhizae 15-20, Radix Angelicae Sinensis 15-20, Rhizoma Atractylodis Macrocephalae 10-15, Caulis Spatholobi 10-15, Semen Cuscutae 15-20, Sculellaria barbata 10-15,
Rhizoma Et Radix Notopterygii 10-15, cicada slough 10-15.
CN104958693A discloses the Chinese medicine of the treatment proliferation of mammary gland, wherein specific open by following raw material medicinal materials
Formula is made：5~15 parts of selfheal, 15~25 parts of safflower, 15~25 parts of Radix Salviae Miltiorrhizae, 5~15 parts of spina gleditsiae, 10~20 parts of Radix Glycyrrhizae,
5~15 parts of Radix Angelicae Sinensis, 5~15 parts of the radix paeoniae rubrathe, 5~15 parts of radix bupleuri, 10~20 parts of Radix Curcumae.
CN106606736A discloses the Chinese medicine of the treatment proliferation of mammary gland, wherein specifically disclosing the drug by following composition by weight
The raw material of ratio：10-20 parts of fiveleaf akebia fruit, 10-20 parts of cornu cerve degelatinatum, 15-25 parts of Radix Salviae Miltiorrhizae, 10-18 parts of spina gleditsiae, selfheal 15-
25 parts, it is 15-25 parts of Radix Curcumae, 10-20 parts of the seed of cowherb, 12-20 parts of safflower, 10-20 parts of curcuma zedoary, 10-18 parts of Radix Angelicae Sinensis, male
10-20 parts of oyster, 15-25 parts of anise, 15-25 parts of fennel seeds are made.
CN105194577A discloses a kind of medicament for treating the proliferation of mammary gland, which is with rhizoma cyperi 15g, Fructus meliae toosendan 15g, member
Hu 10g, Radix Angelicae Sinensis 30g, rhizome of chuanxiong 20g, pangolin 3g, trigone 10g, curcuma zedoary 10g, peach kernel 10g, honeycomb 20g, SEMEN VACCARIAE 15g, the root bark of tree peony
15g, red art 15g are made of raw material.
CN105456668A discloses the Chinese medicine composition of the treatment proliferation of mammary gland, and specifically discloses comprising following parts by weight
Bulk pharmaceutical chemicals：Radix bupleuri 13-18, rhizome of nutgrass flatsedge 5-7, dried orange peel 5-7, peach kernel 8-12, radix cyathulae 8-12, Caulis Spatholobi 8-12, the seed of cowherb
10-15, stem pith of the rice-paper plant 8-12, luffa 10-15, seaweed 8-10, kelp 8-10, fritillaria 5-8, fiveleaf akebia fruit 5-7, rose 5-7, Chuan Shan
First 4-6, Fructus Forsythiae 8-12 and oyster 8-12.
CN105106852A discloses a kind of Chinese medicine preparation for treating the proliferation of mammary gland and breast cancer, it includes following substance：
Turtle shell, stir-baked SQUAMA MANITIS, stiff silkworm, scorpio, gecko, ground beetle, Cornu Cervi, trigone, curcuma zedoary, Radix Angelicae Sinensis, radix bupleuri, green peel, Snakegourd Fruit, sponge gourd
Network, the radix paeoniae rubrathe, Rhizoma Chuanxiong, paris polyphylla, oldenlandia diffusa, edible tulip, peach kernel, safflower, the seed of cowherb, Radix Curcumae, frankincense, myrrh,
Fructus Gleditsia acupuncture, selfheal, oyster, seaweed and geranium wilfordii.
CN1977935A discloses a kind of pharmaceutical composition for treating benigh leiomyoma, using Chinese medicine stir-baked CARAPAX TRIONGCIS with sand then treated with vinegar, water
Treatment benigh leiomyoma is made in leech, ground beetle, the radix paeoniae rubrathe, the root bark of tree peony, ginseng, rhizoma cyperi and corydalis tuber after solvent is extracted, concentrated
Pharmaceutical composition.
The prescription for finding the new treatment proliferation of mammary gland is always the tcm field technical issues that need to address and research weight
Point.
Invention content
Tcm diagnosis and treatment, which is particular about, suits the remedy to the case.The present invention will be divided into according to different onset reason and pathologic stage under the proliferation of mammary gland
Three differentiation of symptoms and signs for classification of syndrome, including hepatic depression demurrage, stagnation of QI-blood phase and phlegm-blood stasis setting period.
The goal of the invention of the present invention is a kind of prescription of proliferation of mammary gland offer for stagnation of QI-blood.Qi and blood mentioned here
Stasis of blood stickiness is primarily referred to as having a case that following symptom：There is breast pain before menstruation menstrual period mostly in patient, and with shouting pain
Based on.Meanwhile when mood is not relaxed, the symptom is more obvious.In addition, its painful area is fixed, lump matter is tough.After lump palpation
There is tenderness, lump and tenderness have exacerbation before menstrual period, can be eased after menstrual period, shouting pain often occurs for sternal rib.And suffer from
Person often has an automatic sigh, and blockage of menstruation or color are purple dim and have clot, and pale tongue is purple or has ecchymosis, and tongue is thin white, uneven pulse.
In order to realize the present invention goal of the invention, we disclose a kind of prescription for treating the stagnation of QI-blood proliferation of mammary gland,
The prescription is made of peach kernel, safflower, army processed, ground beetle, RADIX CURCUMAE.
Peach kernel is rosaceous plant peach Prunus persica (L.) Batsch or mountain peach Prunus davidiana
(Carr.) dry mature seed of Franch..It is harvested after fruit maturation, removes pulp and nucleocapsid, taken out seed, dry.The whole nation
It generally cultivates various regions.
Peach kernel is bitter in taste, sweet, flat.Enter the heart, liver, large intestine channel.With promoting blood circulation, relax bowel, it is relieving cough and asthma the effect of.
Compatibility common at present is used to treat infantile malaria（《Housewarming scholar side》）, regurgitation and emesis（《Card controls invention》）, disk intestines fish gas（《It is general
Ji side》）.
Safflower,（Classification system：Carthamus tinctorius L.）, alias：Red blue flower, thorn safflower, composite family, safflower
Platymiscium, dry tubular flower is orange red, and floral tube is narrow thin, and apex 5 is split, and sliver is narrow linear, and anther yellow is unified into pipe, is higher by
Except sliver, there is column cap exposing in center.Have special fragrance, mildly bitter flavor.With flower piece is long, color is scarlet, the soft person of matter is preferred.
The ground such as main product Henan, Hunan, Sichuan, Xinjiang, Tibet.Safflower nature and flavor are pungent, warm.Enter the heart, Liver Channel.It is mainly used for invigorating blood circulation
Promoting menstruation, stasis-dispelling and pain-killing.If improper use, abdominal discomfort, abdominal pain, diarrhea are generally occurred within, even gastrointestinal bleeding, cramp,
The symptoms such as woman in menstrual period is excessive.
Army processed also known as prepared RADIX ET RHIZOMA RHEI, ripe army.It is to take the rhubarb being cut into small pieces, after being mixed thoroughly with yellow rice wine, put in food steamer and steam,
Or tank interior sealing is put, it sits in kettle, Steam by water bath is saturating, and taking-up is dried.Wherein 100 jin of rheum officinale block is carried out for 30~50 jin with yellow rice wine
It processes.
Army processed is mainly used as purgatives medicine at present, bitter in taste, cold.Enter the Tri-Jiao channels of Hand-Shaoyang, it is simultaneous enter the stomach channel of foot-Yang-ming just, hand
The bright large intestine channel of sun.
In the present invention, preferably described army processed is processed by red rice yellow wine.And the ratio between army further preferably processed and yellow rice wine
Example is 100 Jin Zhi armies with 50 jin of wine processings.
Mostly it is to harvest based on its discharge function in the concocting method of current army processed.And not Qu Zhi armies in the present invention
Lower effect is rushed down, therefore, it is necessary to be improved to existing concocting method, to obtain the effect for having and more preferably treating stagnation of QI-blood
Fruit.
Although being all wine processing, since yellow rice wine is divided into the Huang formed for wheat koji yellow rice wine and red rice yellow wine, the two
Wine ingredient is not quite similar.It is processed using two different yellow rice wine, the material composition that is obtained from army processed, content are different.
The present invention has found that red rice yellow wine processes the army processed obtained for gas by observation of being used as medicine to the army processed obtained under different concocting methods
The blood stasis stickiness proliferation of mammary gland has better therapeutic effect.
Meanwhile we further define the processing ratio of army processed and yellow rice wine.Usually the dosage of yellow rice wine is in 30-50
But it have been found that after 100 Jin Zhi armies use 50 jin of wine processings, it is played in treatment stagnation of QI-blood breast for army processed for jin
The effect of gland hyperplasia is advantageously.
Ground beetle also known as ground bettle, Eupolyphoge sinensis, tortoise.For Corydiidae eupolyphagasinensis walker Eupolyph, aga sin, ensis
The female adult hirudo leech of Walker or polyphagaplancyi Steleophaga Plancyi (Boleny).After capture, put and dead, solarization is scalded in boiling water
Dry or drying.It is distributed in the ground such as Hebei, Shaanxi, Gansu, Qinghai, Shandong, Henan, Jiangsu, Zhejiang, Hunan.Taste is salty, cold in nature, tool
There is the effect of dissipating blood stasis with potent drugs, reunion of fractured tendons and bones.Return liver warp has the effect of dissipating blood stasis with potent drugs, reunion of fractured tendons and bones.
RADIX CURCUMAE is the root tuber of Zingiber herbaceos perennial RADIX CURCUMAE, turmeric, Guangxi zedoary or zedoary.Nature and flavor are pungent,
It is bitter, cold, Return liver, courage, the heart channel of Hang-Shaoyin.There is promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, normalizing gallbladder to cure jaundice.《Bencao Jingshu》In
There is such description to Radix Curcumae：" Radix Curcumae originally enters the gas medicine of blood part, control more than all mass formed by blood stasis persons, the positive uplink for calling blood all belongs to
The ┅ ┅ then not absurd rows of blood drop in interior showing tremendous enthusiasm inflammation, this medicine energy sending down abnormally ascending, gas ".
By peach kernel, safflower, army processed, ground beetle, RADIX CURCUMAE this five kinds of drug combinations in currently available technology, to treat gas
There is not been reported for the method for the blood stasis stickiness proliferation of mammary gland.
Prescription Fang Yiwei disclosed in this invention：
《Chen Su Buddhist nunnery Gynecology Supplement solutions》Have in volume one and be used to peach kernel treat the obstructed category hemostasis person of married woman month water.Inventor passes through clinic
Observation and summary find that the excellent disgruntled situation that stagnation of liver qi is caused to cause bilateral swollen breasts of think of of women is very common, long-term excellent
Think disgruntled female friend, irritability must be caused not smooth, mechanism of qi retardance long then by gas and blood, makes hematogenous blockage, blockage of main and collateral channels, under not
Can supplement nutrition uterus, cannot above support breast, and newborn network impatency, qi depression to blood stasis, condensation is blocking, not general rule pain.The stagnation of the circulation of vital energy with the passing of time then blood stasis
Self-contained.During every blood engorgement through preshoot times, mastosis must aggravate, and qi and blood obtains catharsis after menstrual onset, swell and ache also therewith
Mitigate.Therefore share peach kernel, safflower, army processed, ground beetle, RADIX CURCUMAE, pleasant to stagnation resolvation, the smooth breast of network is logical.It is peach kernel in side, red
Flower, three medicine of army processed and with have promoting blood circulation it is logical it is stagnant, by stagnation resolvation addiction but because peach kernel, army's script pharmacological property processed just relax bowel the benefits of, make
Extravasated blood is from stool downlink.Ground beetle is known as the work(of broken stasis of blood blood, Xiao Disorder lumps in the abdomen, and this law uses its high fiber protein dissolution and anti-freezing
The power of blood extends the duration of the logical stasis of blood and a degree of anti-fibroma degree.RADIX CURCUMAE promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral it
Work(has preferable effect to the intervention and adjustment of married woman's emotional disorder.The effect of promoting blood circulation and removing blood stasis, dredging newborn network is played altogether in full side.
Preferably, peach kernel, safflower, army processed, ground beetle, RADIX CURCUMAE parts by weight for peach kernel 1-10g, safflower 1-10g, army processed
1-10g, ground beetle 1-10g, RADIX CURCUMAE 1-10g.
As a preferred embodiment, the present invention further discloses the prescription and can be made as pill, tablet or capsule.
It can reach promoting blood circulation and removing blood stasis by using technical solution disclosed by the invention, dredge the effect of newborn network.So as to effectively
Treat the stagnation of QI-blood proliferation of mammary gland.
Specific embodiment
In order to better understand the present invention, we in conjunction with specific embodiments further explain the present invention below
It states.
Embodiment 1
Peach kernel 1-10g, safflower 1-10g, army 1-10g processed, ground beetle 1-10g, RADIX CURCUMAE 1-10g five kinds of Chinese medicine are decocted altogether.It decocts extremely
Proportion is 0.1-10.
Embodiment 2
The stagnation of QI-blood proliferation of mammary gland is determined as to the clinical patient with following wholly or largely symptom：Private prosecution mood usually
Emotional, dynamic then roar is roared or grief and indignation is cried, and menstruation is successively irregular, always to delay for premenstrual 1-2 weeks bimastism of the common moon
Distending pain is abnormal, and double breast outside upper quadrants are with tingling sensation, and breast is slightly touched in private prosecution, and then pain aggravates, and clothes is too close-fitting also to feel pain
Discomfort, closely hypogastralgia is apparent in the menarche over the past half year, black through colour cast, and clot is more, and complexion is black dull, and look tired, thin lingual fur
The background color lining purple boundary folder sublingual train of thought of ecchymosis is slightly livid purple, and veins string band is puckery.Such case 100 is chosen altogether.
It is treated with the prescription being prepared in embodiment 1.The disclosed amount of embodiment 1 is primary decoction amount, daily to decoct
It boils once, decoction liquor is drunk in three times.
After taking medicine 2 weeks, there are the distending pain of 85 people, shouting pain to disappear, look light, and the menstrual cycle restores normal.Remaining 15 people is swollen
Bitterly, shouting pain take a favorable turn, and with an easy grace, the menstrual cycle is returned back in normal range (NR).Follow-up tracks 1 year, no recurrence.Total effective rate
It is 100%.It is 1.5 weeks most to take effect soon, and it is 4 weeks that longest, which takes effect,.
Embodiment 3
The 100 leading case example Most patients controlled of we are vitamin A, B6, E by based on hormone medicine, Operand
After the western medicine method treatment of auxiliary, repeatedly, pain feelings aggravate around menstrual period for local shouting pain.
Good control is obtained by the prescription treatment disclosed in this invention for the treatment stagnation of QI-blood proliferation of mammary gland
Therapeutic effect.Compared to western medical treatment mode, tcm prescription therapeutic scheme disclosed by the invention is mild, significant in efficacy, can be vast
Mammary gland disease patient releases pain, far from the danger for suffering from breast cancer.
Claims (5)
1. treat the prescription of the stagnation of QI-blood proliferation of mammary gland, it is characterized in that, the prescription is by peach kernel, safflower, army processed, ground beetle, wide
Radix Curcumae forms.
2. the prescription of the treatment stagnation of QI-blood proliferation of mammary gland according to claim 1, it is characterized in that, peach kernel, safflower, system
Army, ground beetle, RADIX CURCUMAE parts by weight for peach kernel 1-10g, safflower 1-10g, army 1-10g processed, ground beetle 1-10g, RADIX CURCUMAE 1-
10g。
3. the prescription of the treatment stagnation of QI-blood proliferation of mammary gland according to claim 1 or 2, it is characterized in that, prescription can be done
Piece agent, pill or capsule.
4. the prescription of the treatment stagnation of QI-blood proliferation of mammary gland according to claim 1, it is characterized in that, the army processed is by red yeast rice
Wine processing.
5. the prescription of the treatment stagnation of QI-blood proliferation of mammary gland according to claim 4, it is characterized in that, between army processed and yellow rice wine
Ratio for 100 Jin Zhi armies with 50 jin of wine processings.
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| CN201810182935.4A CN108159359A (en) | 2018-03-06 | 2018-03-06 | Treat the prescription of the stagnation of QI-blood proliferation of mammary gland |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230160977A (en) | 2022-05-17 | 2023-11-27 | 에이치앤오바이오시스(주) | Extracts of Five or More Herbal Plants Used for Anticancer Therapy |
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| WO2016183783A1 (en) * | 2015-05-18 | 2016-11-24 | 张甘霖 | Traditional chinese medicine for treating hyperplasia of mammary glands |
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772739A (en) * | 2012-07-15 | 2012-11-14 | 李承平 | Recovery tablets for soothing livers and dredging collaterals |
| WO2016183783A1 (en) * | 2015-05-18 | 2016-11-24 | 张甘霖 | Traditional chinese medicine for treating hyperplasia of mammary glands |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230160977A (en) | 2022-05-17 | 2023-11-27 | 에이치앤오바이오시스(주) | Extracts of Five or More Herbal Plants Used for Anticancer Therapy |
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