CN108158958A - A kind of efficient whitening and spot eliminating cream with antianaphylaxis function - Google Patents

A kind of efficient whitening and spot eliminating cream with antianaphylaxis function Download PDF

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Publication number
CN108158958A
CN108158958A CN201810223063.1A CN201810223063A CN108158958A CN 108158958 A CN108158958 A CN 108158958A CN 201810223063 A CN201810223063 A CN 201810223063A CN 108158958 A CN108158958 A CN 108158958A
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Prior art keywords
saualane
skin
extract
active component
whitening
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CN201810223063.1A
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马峰
苏玉增
梁秀红
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Pegasus (anhui) Chinese Medicine Polytron Technologies Inc
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Pegasus (anhui) Chinese Medicine Polytron Technologies Inc
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Priority to CN201810223063.1A priority Critical patent/CN108158958A/en
Publication of CN108158958A publication Critical patent/CN108158958A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of efficient whitening and spot eliminating creams with antianaphylaxis function, and raw material is prepared including following weight percent:Active component extract 5 30%, Catergen 10%, ursin 0.5 3%, notoginsenoside 3 8%, niacinamide 1 4%, astaxanthin 0.5 2%, natural propolis extract 2 3%, saualane 1 2%, grease 3 5%, moisturizer 3 15%, deionized water 10 85%, primary raw material of the invention are active component extract, vitamin C, ursin, niacinamide, astaxanthin, natural propolis extract, saualane, grease, moisturizer;Saualane can strengthen maintenance epidermis; it is effectively formed natural protective film; help the balance between skin and sebum; saualane can also inhibit the peroxidating of skin lipid, and schizonepeta can promote skin blood cycle to strengthen, there is slight antipyretic effect; it can promote the healing of skin infection disease and the absorption of disease damage tissue; with antipruritic antianaphylactic effect, side effect is not present in the present invention, and use is also very convenient.

Description

A kind of efficient whitening and spot eliminating cream with antianaphylaxis function
Technical field
It is more particularly to a kind of efficient with antianaphylaxis function the present invention relates to a kind of whitening and spot eliminating cream and preparation method thereof Whitening and spot eliminating cream and preparation method thereof belongs to medical medicine technical field.
Background technology
The formation of color spot is the pigment calm knot on the skin under the influence of the factors such as ultraviolet light, hormone, heredity and aging Fruit, therefore, such product are mainly to rely on addition in cream matrix to inhibit and restore the active ingredient of melanin and reach and dispel The purpose of spot, currently used nti-freckle additive have ursin, kojic acid, vitamin C derivatives, tartaric acid and some Chinese medical extracts Deng.Whitening and spot eliminating cream refers to that, the colour of skin dark and gloomy to skin be irregular and the color spot of skin surface has and centainly inhibits, dissolves and dispel work Skin emulsification cream.Such product be mainly rely in cream matrix addition inhibit and reduction melanin it is effective into Divide and achieve the purpose that nti-freckle.
Existing whitening and spot eliminating cream effect is not notable enough, and easy allergy after people's smearing of many skin sensitivities, exists The problem of more.
Invention content
The present invention provides a kind of efficient whitening and spot eliminating cream with antianaphylaxis function and preparation method thereof.
In order to solve the above technical problem, the present invention provides following technical solutions:
A kind of efficient whitening and spot eliminating cream with antianaphylaxis function of the present invention, the preparation including following weight percent are former Material:Active component extract 5-30%, Catergen -10%, ursin 0.5-3%, notoginsenoside 3-8%, niacinamide 1- 4%th, astaxanthin 0.5-2%, natural propolis extract 2-3%, saualane 1-2%, grease 3-5%, moisturizer 3-15%, go from Sub- water 10-85%.
As a preferred technical solution of the present invention, raw material is prepared including following parts by weight:Active component extract 15%th, vitamin C 6%, ursin 1.5%, notoginsenoside 5%, niacinamide 2.5%, astaxanthin 1%, natural propolis extract 2.5%th, saualane 1.5%, grease 4%, moisturizer 9%, deionized water 52%.
As a preferred technical solution of the present invention, the raw material weight percentage of the active component extract is:It is yellow Melon 2-20%, grape pip 2-20%, Chinese yam 3-15%, Flos Hibisci Mutabilis 2-20%, Radix Salviae Miltiorrhizae 2-10%, schizonepeta 3-10%, root of Dahurain angelica 5- 10%.
As a preferred technical solution of the present invention, the grease is the smooth olive oleate of sorb, stearic acid, alcohol benzene first Two or more in acid esters, polydimethylsiloxanes.
As a preferred technical solution of the present invention, the moisturizer is sodium hyaluronate 2-4%, glycerine 3-10%, anti-bad One or more in hematic acid phosphate magnesium 5-10%.
The present invention also provides the preparation methods of the above-mentioned efficient whitening and spot eliminating cream with antianaphylaxis function:
Step (1), by the active component extract in cucumber, grape pip, Chinese yam, Flos Hibisci Mutabilis, Radix Salviae Miltiorrhizae, schizonepeta, the root of Dahurain angelica and Ethyl alcohol is according to 1:5 to 1:10 ratio is impregnated, soaking time 1-3 days;
Step (2) filters the solution after immersion, collects filtrate, spare after filtrate is concentrated by evaporation;
Active component extract obtained in step (2), vitamin C, moisturizer, deionized water are added in water by step (3) In phase pot, 70-80 DEG C is heated to, is stirred evenly, it is spare;
Step (4) adds ursin, notoginsenoside, niacinamide, astaxanthin, natural propolis extract, saualane, grease Enter in oil phase pot, be heated to 70-85 DEG C, be uniformly dispersed, it is spare;
Mixture in step (3) and (4) is transferred in emulsification pot, homogeneous 10min by step (5), after cooling, stirring Uniformly to get whitening and spot eliminating cream.
Wherein ursin is derived from the natural active matter of green plants, collection " green plants, safe and reliable " and " efficiently takes off Color " three conjunction is humorous to be unified in integrated depigmentation of skin component, it can rapidly permeate into skin, not influence the same of cell Proliferation concentration When, the activity of the tyrosinase in skin can be effectively inhibited, blocks the formation of melanin, is directly tied by itself and junket ammonia enzyme It closes, accelerates the decomposition and excretion of melanin, so as to reduce Skin pigmentation, dispelling stain and freckle, and also it is thin to melanin Born of the same parents do not generate the side effects such as toxic, irritation, sensitization, while also have the effect of sterilization, anti-inflammatory.
Natural astaxanthin (natural astacin) one of most strong natural in the world, the oxygen in effective scavenger-cell Free radical, enhance cytothesis ability, maintain organism balance and reduce senile cell accumulation, from inside to outside protect cell and DNA health so as to protect skin health, promotes hair growth, and anti-aging alleviates sports fatigue, invigorates.
The advantageous effect that is reached of the present invention is:A kind of efficient whitening and spot eliminating cream with antianaphylaxis function of the present invention, it is main Want raw material be active component extract, vitamin C, ursin, notoginsenoside, niacinamide, astaxanthin, natural propolis extract, Saualane, grease, moisturizer;Promoting blood circulation is promoted blood circulation active, has the work for inhibiting platelet aggregation and increasing heart and brain blood flow With saualane can strengthen maintenance epidermis, be effectively formed natural protective film, help the balance between skin and sebum, saualane is also It can inhibit the peroxidating of skin lipid, can effectively infiltrate through skin, and promote the proliferation of skin base cell, it is old to delaying skin Change, improving and eliminating chloasma has apparent physiologic effect.Proflavanol in active component extract is containing a large amount of preceding flowers Green element OPC, procyanidins protecting human bodies skin are invaded from free radical;This function makes skin increase elasticity, not by adverse circumstances Infringement.The root of Dahurain angelica expels pathogenic wind from the body surface, saturating hair key, clearing the nasal passage, eliminating cold to stop pain, eliminating dampness detoxication.The kind wind for controlling head skin, external application Cutaneous pruritus can be treated, can promote to be destroyed the absorption of tissue, have promotion to absorb or promote it to chronic ulcer, scytitis The effect of suppuration, schizonepeta can promote skin blood cycle to strengthen, have slight antipyretic effect, can promote skin infection disease The healing of disease and the absorption of disease damage tissue, have antipruritic antianaphylactic effect, the present invention is there is no side effect, using also very square Just.
Specific embodiment
The preferred embodiment of the present invention is illustrated below, it should be understood that preferred embodiment described herein is only used In the description and interpretation present invention, it is not intended to limit the present invention.
Embodiment 1
A kind of efficient whitening and spot eliminating cream with antianaphylaxis function of invention includes the system of following weight percent Standby raw material:Active component extract 5-30%, Catergen -10%, ursin 0.5-3%, notoginsenoside 3-8%, niacinamide 1-4%, astaxanthin 0.5-2%, natural propolis extract 2-3%, saualane 1-2%, grease 3-5%, moisturizer 3-15%, Deionized water 10-85%.
Preparation method is:1) active constituent in cucumber, grape pip, Chinese yam, Flos Hibisci Mutabilis, Radix Salviae Miltiorrhizae, schizonepeta, the root of Dahurain angelica is extracted Object and ethyl alcohol are according to 1:5 to 1:10 ratio is impregnated, soaking time 1-3 days;
2) solution after immersion is filtered, collects filtrate, it is spare after filtrate is concentrated by evaporation;
3) 2) active component extract obtained in, vitamin C, moisturizer, deionized water are added in water phase pot, heating To 70-80 DEG C, stir evenly, it is spare;
4) ursin, notoginsenoside, niacinamide, astaxanthin, natural propolis extract, saualane, grease are added in into oil phase In pot, 70-85 DEG C is heated to, is uniformly dispersed, it is spare;
And 4) 5) 3) mixture in is transferred in emulsification pot, homogeneous 10min after cooling, is stirred evenly to get whitening Content in freckle cream.
A kind of efficient whitening and spot eliminating cream with antianaphylaxis function of the present invention, primary raw material are active component extract, dimension Raw element C, ursin, notoginsenoside, niacinamide, astaxanthin, natural propolis extract, saualane, grease, moisturizer;Promoting blood circulation is dispelled The stasis of blood is promoted blood circulation active, is had the function of to inhibit platelet aggregation and is increased heart and brain blood flow, and saualane can strengthen maintenance epidermis, Natural protective film is effectively formed, helps the balance between skin and sebum, saualane can also inhibit the peroxidating of skin lipid, can have Effect infiltrates through skin, and promote the proliferation of skin base cell, and to delay skin aging, improving and eliminating chloasma has significantly Physiologic effect.Proflavanol in active component extract is containing a large amount of procyanidins OPC, procyanidins protecting human bodies skin Skin is invaded from free radical;This function makes skin increase elasticity, is not encroached on by adverse circumstances.The root of Dahurain angelica expels pathogenic wind from the body surface, saturating hair Key, clearing the nasal passage, eliminating cold to stop pain, eliminating dampness detoxication.The kind wind for controlling head skin, external application can treat cutaneous pruritus, can promote The absorption of tissue is destroyed, play the role of promoting to absorb to chronic ulcer, scytitis or it is promoted to suppurate, schizonepeta can promote skin Skin blood circulation is strengthened, and has slight antipyretic effect, can promote the healing of skin infection disease and the suction of disease damage tissue It receives, there is antipruritic antianaphylactic effect, side effect is not present in the present invention, and use is also very convenient.
Experimental data:
100 ages between 30~50 years old, the women that face has color spot is randomly divided into two groups, and A groups apply sooner or later daily Smear the whitening and spot eliminating cream of the present invention of peanut size, B groups daily sooner or later one peanut size of smearing on the market Common content in freckle cream.Result after 4 months is shown:
Finally it should be noted that:The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used To modify to the technical solution recorded in foregoing embodiments or carry out equivalent replacement to which part technical characteristic. All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention's Within protection domain.

Claims (6)

1. a kind of efficient whitening and spot eliminating cream with antianaphylaxis function, which is characterized in that include the preparation of following weight percent Raw material:Active component extract 5-30%, Catergen -10%, ursin 0.5-3%, notoginsenoside 3-8%, niacinamide 1- 4%th, astaxanthin 0.5-2%, natural propolis extract 2-3%, saualane 1-2%, grease 3-5%, moisturizer 3-15%, go from Sub- water 10-85%.
2. a kind of efficient whitening and spot eliminating cream with antianaphylaxis function according to claim 1, which is characterized in that including with Lower parts by weight prepare raw material:Active component extract 15%, vitamin C 6%, ursin 1.5%, notoginsenoside 5%, nicotinoyl Amine 2.5%, astaxanthin 1%, natural propolis extract 2.5%, saualane 1.5%, grease 4%, moisturizer 9%, deionized water 52%.
A kind of 3. efficient whitening and spot eliminating cream with antianaphylaxis function according to claim 1, which is characterized in that the work The raw material weight percentage of property component extract is:Cucumber 2-20%, grape pip 2-20%, Chinese yam 3-15%, Flos Hibisci Mutabilis 2- 20%th, Radix Salviae Miltiorrhizae 2-10%, schizonepeta 3-10%, root of Dahurain angelica 5-10%.
A kind of 4. efficient whitening and spot eliminating cream with antianaphylaxis function according to claim 1, which is characterized in that the oil Fat is two or more in the smooth olive oleate of sorb, stearic acid, alcohol benzoic ether, polydimethylsiloxanes.
A kind of 5. efficient whitening and spot eliminating cream with antianaphylaxis function according to claim 1, which is characterized in that the guarantor Humectant is sodium hyaluronate 2-4%, the one or more in glycerine 3-10%, magnesium ascorbyl phosphate 5-10%.
6. a kind of preparation method of efficient whitening and spot eliminating cream with antianaphylaxis function according to claim 1, feature It is, includes the following steps:
1) by the active component extract in cucumber, grape pip, Chinese yam, Flos Hibisci Mutabilis, Radix Salviae Miltiorrhizae, schizonepeta, the root of Dahurain angelica and ethyl alcohol according to 1:5 To 1:10 ratio is impregnated, soaking time 1-3 days;
2) solution after immersion is filtered, collects filtrate, it is spare after filtrate is concentrated by evaporation;
3) 2) active component extract obtained in, vitamin C, moisturizer, deionized water are added in water phase pot, are heated to It 70-80 DEG C, stirs evenly, it is spare;
4) ursin, niacinamide, notoginsenoside, astaxanthin, natural propolis extract, saualane, grease are added in oil phase pot, 70-85 DEG C is heated to, is uniformly dispersed, it is spare;
And 4) 5) 3) mixture in is transferred in emulsification pot, homogeneous 10min after cooling, is stirred evenly to get whitening spot-removing Frost.
CN201810223063.1A 2018-03-19 2018-03-19 A kind of efficient whitening and spot eliminating cream with antianaphylaxis function Pending CN108158958A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110314130A (en) * 2019-08-13 2019-10-11 广州海梦科化妆品有限公司 Stoste and preparation method thereof is repaired in a kind of whitening
CN112237551A (en) * 2020-11-13 2021-01-19 深圳市薇美经典科技发展有限公司 Preparation method of repairing skin care preparation

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104080438A (en) * 2011-11-30 2014-10-01 味之素株式会社 Whitening cosmetic
CN104523484A (en) * 2014-12-10 2015-04-22 唯美度科技(北京)有限公司 Whitening and balancing eye cream with mild formula
CN104739690A (en) * 2013-12-28 2015-07-01 大连美乐生物技术开发有限公司 Whitening cream and making method thereof
CN105125466A (en) * 2015-09-29 2015-12-09 青岛海之源智能技术有限公司 Freckle removing night cream and preparing method thereof
CN106132391A (en) * 2014-03-14 2016-11-16 富士胶片株式会社 Dispersive composition and cosmetics
CN106420546A (en) * 2015-07-27 2017-02-22 李尧 Skin-whitening moisturisor
CN106852843A (en) * 2016-12-06 2017-06-16 长沙协浩吉生物工程有限公司 A kind of compound method of anti-aging day cream

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104080438A (en) * 2011-11-30 2014-10-01 味之素株式会社 Whitening cosmetic
CN104739690A (en) * 2013-12-28 2015-07-01 大连美乐生物技术开发有限公司 Whitening cream and making method thereof
CN106132391A (en) * 2014-03-14 2016-11-16 富士胶片株式会社 Dispersive composition and cosmetics
CN104523484A (en) * 2014-12-10 2015-04-22 唯美度科技(北京)有限公司 Whitening and balancing eye cream with mild formula
CN106420546A (en) * 2015-07-27 2017-02-22 李尧 Skin-whitening moisturisor
CN105125466A (en) * 2015-09-29 2015-12-09 青岛海之源智能技术有限公司 Freckle removing night cream and preparing method thereof
CN106852843A (en) * 2016-12-06 2017-06-16 长沙协浩吉生物工程有限公司 A kind of compound method of anti-aging day cream

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110314130A (en) * 2019-08-13 2019-10-11 广州海梦科化妆品有限公司 Stoste and preparation method thereof is repaired in a kind of whitening
CN112237551A (en) * 2020-11-13 2021-01-19 深圳市薇美经典科技发展有限公司 Preparation method of repairing skin care preparation

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Application publication date: 20180615

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