CN108117961A - A kind of minuent health preserving wine and preparation method thereof - Google Patents
A kind of minuent health preserving wine and preparation method thereof Download PDFInfo
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- CN108117961A CN108117961A CN201810078614.XA CN201810078614A CN108117961A CN 108117961 A CN108117961 A CN 108117961A CN 201810078614 A CN201810078614 A CN 201810078614A CN 108117961 A CN108117961 A CN 108117961A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
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Abstract
The present invention relates to health product technology fields, especially a kind of low health preserving wine and preparation method thereof, by taking the processing steps such as crushing, ultrasonic extraction, concentration extraction, ageing, refined filtration, so that the active ingredient in pinenut, arillus longan, prepared rhizome of rehmannia, the fruit of Cherokee rose, Poria cocos, Radix Angelicae Sinensis, male silk moth, safflower, matrimony vine, asparagus fern, jujube, dried orange peel is quickly dissolved into wine, and it is arranged in pairs or groups by rational compatibility and proportion design, and then synergistic effect so that health preserving wine of the invention plays an important role of nourishing liver kidney-nourishing, sedate tranquilizing the mind, replenishing blood for nourishing heart.
Description
Technical field
The present invention relates to health product technology field, especially a kind of low health preserving wine and preparation method thereof.
Background technology
Chinese medicament healthcare wine be using brewed wine, Spirit or edible alcohol as base liquor, add in a certain proportion of Chinese medicine or its
Effective extract, using alcoholic drink made of corresponding technique.The scientific compatibility of Chinese medicament healthcare wine medication, with health be healthy and strong for
It is main, it is different according to function, tonifying Qi, blood enriching and yin nourishing, yang-tonifying and the types such as qi-blood tonifying can be divided into.Therefore, Chinese medicament healthcare wine has
The effects that improvement human quality, raising disease resistance, beauty moisturizing, diseases prevention get rid of illness, slow down aging, prolonging life, development prospect
Considerable, space is huge, is a very promising rising industry.
Chinese medicament healthcare wine can be nourished the body, consumption market is more and more ripe, and people are in living standard due to abundant raw materials
On the premise of raising, not only requirement will have abundanter material enjoyment, and be supported with greater need for permanent health, come full side with this
Improve the quality of living to position.But most of Chinese medicament healthcare wine also rests on the stage that medicinal material prepares health preserving wine of impregnating at present, it is right
It cannot meet in time in the vigorous market demand.
The content of the invention
In order to solve the technical issues of existing at present, the present invention provides a kind of low health preserving wines and preparation method thereof.
The specific time is achieved by the following technical programs：
A kind of minuent health preserving wine, medicinal material include as follows in parts by mass：Pinenut 100~140, arillus longan 90~110, cultivated land
Huang 40~60, the fruit of Cherokee rose 20~40, Poria cocos 20~40, Radix Angelicae Sinensis 20~40, male silk moth 5~15, safflower 3~8, matrimony vine 3~8, day
Winter 3~8, jujube 3~8, dried orange peel 3~8.
Medicinal material includes as follows in parts by mass：Pinenut 120, arillus longan 100, prepared rhizome of rehmannia 50, the fruit of Cherokee rose 30, Poria cocos 30, when
Return 30, male silk moth 10, safflower 5, matrimony vine 5, asparagus fern 5, jujube 5, dried orange peel 5.
Above-mentioned minuent health method for preparing medicated wine, comprises the following steps：
(1) medicinal material is handled：Pinenut, arillus longan, prepared rhizome of rehmannia, the fruit of Cherokee rose, Poria cocos, Radix Angelicae Sinensis, male silk moth, red is weighed by formula ratio
Flower, matrimony vine, asparagus fern, jujube, dried orange peel, are respectively washed, and dry, pulverize, and sieving obtains medicinal powder；
(2) ultrasonic extraction：Medicinal powder is added in alcohol, ultrasound obtains medicinal material stoste；
(3) filtering and concentrating：Medicinal material stoste is depressurized and is filtered, paste is concentrated the filtrate to using rotary evaporation, obtains medicinal material
Medicinal extract；
(4) hook tune：By white wine decreasing concentration, the white wine of medicinal material medicinal extract and decreasing concentration is according to 1g：40ml ratios carry out hook tune；
(5) it is aged：Ultrasonic aging is used to the wine after hook tune；
(6) refined filtration：Using diatomite strainer to after ageing wine carry out refined filtration to get.
The medicinal material processing, drying temperature are 33~37 DEG C, and using Universalpulverizer grinding medicinal materials, sieving is using No. four
Stainless steel standard medicine sieves.
The ultrasonic extraction, alcohol concentration are 55.50%~56.30%, and the mass ratio of medicinal powder and alcohol is 1:
9.12, ultrasonic temperature is 53~57 DEG C, and ultrasonic time is 15~25min.
The decreasing concentration is from 52 ° near 38 ° by white wine.
The ageing, supersonic frequency are 35~45kHz, and ultrasonic temperature is 35~45 DEG C, 60~70min of ultrasonic time.
The refined filtration, the filtering accuracy of diatomite strainer is 0.45 μm.
Compared with prior art, the technique effect of the invention is embodied in：
By take crushing, ultrasonic extraction, concentration extraction, ageing, refined filtration and etc. technique, by the active ingredient in medicinal material
Rapid extraction comes out, and greatly speeds up the preparation process of health preserving wine, and easy to operate, is suitble to large-scale production.
To pinenut, arillus longan, prepared rhizome of rehmannia, the fruit of Cherokee rose, Poria cocos, Radix Angelicae Sinensis, male silk moth, safflower, matrimony vine, asparagus fern, jujube, dried orange peel
Carry out rational compatibility and proportion design, utilize the synergistic function of each traditional Chinese medicine ingredients so that the present invention have nourishing liver kidney-nourishing,
Sedate is calmed the nerves, the effect of replenishing blood for nourishing heart.
Specific embodiment
Technical scheme is described further with reference to specific embodiment and test example, but will
The scope of protection is asked to be not only limited to made description.
Embodiment 1
A kind of minuent health method for preparing medicated wine, comprises the following steps：
(1) medicinal material is handled：Weigh pinenut 100g, arillus longan 90g, prepared rhizome of rehmannia 40g, fruit of Cherokee rose 20g, Poria cocos 20g, Radix Angelicae Sinensis
20g, male silk moth 5g, safflower 3g, matrimony vine 3g, asparagus fern 3g, jujube 3g, dried orange peel 3g, are respectively washed, dry, pulverize, and sieving obtains medicine
Material powder；
(2) ultrasonic extraction：Medicinal powder is added in alcohol, ultrasound obtains medicinal material stoste；
(3) filtering and concentrating：Medicinal material stoste is depressurized and is filtered, paste is concentrated the filtrate to using rotary evaporation, obtains medicinal material
Medicinal extract；
(4) hook tune：By white wine decreasing concentration, the white wine of medicinal material medicinal extract and decreasing concentration is according to 1g：40ml ratios carry out hook tune；
(5) it is aged：Ultrasonic aging is used to the wine after hook tune；
(6) refined filtration：Using diatomite strainer to after ageing wine carry out refined filtration to get.
The medicinal material processing, drying temperature are 33 DEG C, and using Universalpulverizer grinding medicinal materials, sieving is stainless using No. four
Steel standard medicine sieves.
The mass ratio of the ultrasonic extraction, alcohol concentration 55.50%%, medicinal powder and alcohol is 1:It is 9.12 super
Sound temperature is 53 DEG C, ultrasonic time 15min.
The decreasing concentration is from 52 ° near 38 ° by white wine.
The ageing, supersonic frequency 35kHz, ultrasonic temperature are 35 DEG C, ultrasonic time 60min.
The refined filtration, the filtering accuracy of diatomite strainer is 0.45 μm.
Embodiment 2
A kind of minuent health method for preparing medicated wine, comprises the following steps：
(1) medicinal material is handled：Weigh pinenut 120g, arillus longan 100g, prepared rhizome of rehmannia 50g, fruit of Cherokee rose 30g, Poria cocos 30g, Radix Angelicae Sinensis
30g, male silk moth 10g, safflower 5g, matrimony vine 5g, asparagus fern 5g, jujube 5g, dried orange peel 5g, are respectively washed, dry, pulverize, and sieving obtains medicine
Material powder；
(2) ultrasonic extraction：Medicinal powder is added in alcohol, ultrasound obtains medicinal material stoste；
(3) filtering and concentrating：Medicinal material stoste is depressurized and is filtered, paste is concentrated the filtrate to using rotary evaporation, obtains medicinal material
Medicinal extract；
(4) hook tune：By white wine decreasing concentration, the white wine of medicinal material medicinal extract and decreasing concentration is according to 1g：40ml ratios carry out hook tune；
(5) it is aged：Ultrasonic aging is used to the wine after hook tune；
(6) refined filtration：Using diatomite strainer to after ageing wine carry out refined filtration to get.
The medicinal material processing, drying temperature are 35 DEG C, and using Universalpulverizer grinding medicinal materials, sieving is stainless using No. four
Steel standard medicine sieves.
The mass ratio of the ultrasonic extraction, alcohol concentration 55.91%, medicinal powder and alcohol is 1:9.12 ultrasound
Temperature is 55 DEG C, ultrasonic time 20min.
The decreasing concentration is from 52 ° near 38 ° by white wine.
The ageing, supersonic frequency 40kHz, ultrasonic temperature are 40 DEG C, ultrasonic time 65min.
The refined filtration, the filtering accuracy of diatomite strainer is 0.45 μm.
Embodiment 3
A kind of minuent health method for preparing medicated wine, comprises the following steps：
(1) medicinal material is handled：Weigh pinenut 140g, arillus longan 110g, prepared rhizome of rehmannia 60g, fruit of Cherokee rose 40g, Poria cocos 40g, Radix Angelicae Sinensis
40g, male silk moth 15g, safflower 8g, matrimony vine 8g, asparagus fern 8g, jujube 8g, dried orange peel 8g, are respectively washed, dry, pulverize, and sieving obtains medicine
Material powder；
(2) ultrasonic extraction：Medicinal powder is added in alcohol, ultrasound obtains medicinal material stoste；
(3) filtering and concentrating：Medicinal material stoste is depressurized and is filtered, paste is concentrated the filtrate to using rotary evaporation, obtains medicinal material
Medicinal extract；
(4) hook tune：By white wine decreasing concentration, the white wine of medicinal material medicinal extract and decreasing concentration is according to 1g：40ml ratios carry out hook tune；
(5) it is aged：Ultrasonic aging is used to the wine after hook tune；
(6) refined filtration：Using diatomite strainer to after ageing wine carry out refined filtration to get.
The medicinal material processing, drying temperature are 37 DEG C, and using Universalpulverizer grinding medicinal materials, sieving is stainless using No. four
Steel standard medicine sieves.
The mass ratio of the ultrasonic extraction, alcohol concentration 56.30%, medicinal powder and alcohol is 1:9.12 ultrasound
Temperature is 57 DEG C, ultrasonic time 25min.
The decreasing concentration is from 52 ° near 38 ° by white wine.
The ageing, supersonic frequency 45kHz, ultrasonic temperature are 45 DEG C, ultrasonic time 70min.
The refined filtration, the filtering accuracy of diatomite strainer is 0.45 μm.
Test example 1
100 mouse are randomly divided into 5 groups, are divided into test group 1-3, control group, blank group, each 20 of every group of mouse is female
Male double.The mouse of test group 1-3 is gavaged respectively using the low health preserving wine of embodiment 1-3, the mouse of control group is using general
Logical white wine gavages, and the mouse of blank group is gavaged using water.The amount of gavaging continuously gavages 30 days, using 5ml/kg as standard then to each
Group mouse detection Sexual Hormone Contents in Serum.Male mouse detects testosterone concentration, and female mice detection follicular stimulating hormone content, acquired results numerical value is by calculation
Art average value value.It the results are shown in Table 1：
Table 1
As can be seen from the above table, the mouse of test group 1-3 is after the low health preserving wine of embodiment 1-3 is gavaged, male mouse with it is female
The Sexual Hormone Contents in Serum of mouse, which has, to be obviously improved, and shows that the present invention has the work(for improving sexuality ability to a certain extent
Effect.
Test example 2
It chooses 37 voluntarily to participate in and suffer from the people of insomnia, the range of age was at 21~65 years old, and 25 people of male, schoolgirl 12
People takes the low health preserving wine of the present invention for continuous 3 months.Health-care effect criterion is：
It is effective：The length of one's sleep recovers normal, falls asleep average time in 1~10min, and when sleeping at night will not wake up with a start, and sleep
It sleeps deep, energetic after waking up, day time spirit nothing is decreased obviously.
Effectively：The length of one's sleep has increased slightly, and falls asleep average time in 10~15min, daydream number is reduced.
It is invalid：Insomnia situation is without any improvement.
The results are shown in Table 2：
Table 2
In addition, this researcher is suffered from also to 29 patients with Anemia using the low health preserving wine of the present invention
Person took the cycle as 3 months, and to carrying out Follow-up observation before and after the treatment for diseases of patient, randomly select it is several following, it is specific
Effect is as follows：
Week certain, female, 52 years old, Xingyi of Guizhou, before the treatment with anaemia, usually weak and feeble, pale, appetite was not
The phenomenon that shaking, being present with dizziness, headache once in a while, work hours attention cannot be concentrated, and work efficiency is poor, after strenuous exercise
It is present with palpitation, is short of breath；By after supper 2 when small after take the present invention low health preserving wine 25ml, continue 1 month
Afterwards, have rosy cheeks, breathing is smooth, does not occur the phenomenon that dizzy, headache again.
Poplar, female, 32 years old, Guizhou southeast of Guizhou Province Song Taoxian, before the treatment with anaemia for many years, show as easily it is tired,
Ochrodermia, lip whiting, shortness of breath uncomfortable in chest, menstrual period are irregular, menorrhalgia, when hospital is checked, quantity of leucocyte
4.82×109/ L, erythrocyte number 3.82 × 1012/ L, platelet counts 1.38 × 1011/ L, hemoglobin 129g/L；By every
The low health preserving wine 50ml of the present invention is taken during its supper, continuous 2 months, routine blood indexes had apparent rising, quantity of leucocyte
6.52×109/ L, erythrocyte number 4.36 × 1012/ L, platelet counts 214 × 109/ L, hemoglobin 141g/L, physiology week
Phase recovers normal.
Lee, man, 45 years old, anaemia was contained in Guizhou Province south Majiang County before the treatment, was often accompanied by dizziness and tinnitus, weak
Easily tired symptom, and night urine is more, after farming labor service, it may appear that pale complexion, nervous asthma have the phenomenon that dim eyesight once in a while；
By sleep every night 1 when small before rich in the present invention low health preserving wine 25ml, after continuing 2 months, the symptom of dizziness and tinnitus disappears
It loses, night, sleep quality was good, and daytime is energetic, and efficiency of being engaged in agriculture greatly improves without phenomenon of getting up in the night to urinate.
Claims (8)
1. a kind of minuent health preserving wine, which is characterized in that medicinal material includes as follows in parts by mass：Pinenut 100~140, arillus longan 90
~110, prepared rhizome of rehmannia 40~60, the fruit of Cherokee rose 20~40, Poria cocos 20~40, Radix Angelicae Sinensis 20~40, male silk moth 5~15, safflower 3~8, Chinese holly
Qi 3~8, asparagus fern 3~8, jujube 3~8, dried orange peel 3~8.
2. minuent health preserving wine as described in claim 1, which is characterized in that medicinal material includes as follows in parts by mass：Pinenut 120,
It is arillus longan 100, prepared rhizome of rehmannia 50, the fruit of Cherokee rose 30, Poria cocos 30, Radix Angelicae Sinensis 30, male silk moth 10, safflower 5, matrimony vine 5, asparagus fern 5, jujube 5, old
Skin 5.
3. a kind of minuent health method for preparing medicated wine, which is characterized in that comprise the following steps：
(1) medicinal material is handled：By formula ratio weigh pinenut, arillus longan, prepared rhizome of rehmannia, the fruit of Cherokee rose, Poria cocos, Radix Angelicae Sinensis, male silk moth, safflower,
Matrimony vine, asparagus fern, jujube, dried orange peel, are respectively washed, and dry, pulverize, and sieving obtains medicinal powder；
(2) ultrasonic extraction：Medicinal powder is added in alcohol, ultrasound obtains medicinal material stoste；
(3) filtering and concentrating：Medicinal material stoste is depressurized and is filtered, paste is concentrated the filtrate to using rotary evaporation, obtains medicinal material medicinal extract；
(4) hook tune：By white wine decreasing concentration, the white wine of medicinal material medicinal extract and decreasing concentration is according to 1g：40ml ratios carry out hook tune；
(5) it is aged：Ultrasonic aging is used to the wine after hook tune；
(6) refined filtration：Using diatomite strainer to after ageing wine carry out refined filtration to get.
4. minuent health method for preparing medicated wine as claimed in claim 4, which is characterized in that the medicinal material processing, drying temperature
For 33~37 DEG C, using Universalpulverizer grinding medicinal materials, sieving is sieved using No. four stainless steel standard medicines.
5. minuent health method for preparing medicated wine as claimed in claim 4, which is characterized in that the ultrasonic extraction, alcohol concentration
For 55.50%~56.30%, the mass ratio of medicinal powder and alcohol is 1:9.12, ultrasonic temperature is 53~57 DEG C, ultrasonic time
For 15~25min.
6. minuent health method for preparing medicated wine as claimed in claim 4, which is characterized in that the decreasing concentration is from 52 ° by white wine
Near 38 °.
7. minuent health method for preparing medicated wine as claimed in claim 4, which is characterized in that the ageing, supersonic frequency 35
~45kHz, ultrasonic temperature are 35~45 DEG C, 60~70min of ultrasonic time.
8. minuent health method for preparing medicated wine as claimed in claim 4, which is characterized in that the refined filtration, diatomite strainer
Filtering accuracy be 0.45 μm.
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| CN109825410A (en) * | 2019-03-29 | 2019-05-31 | 河南友林酒业有限公司 | A kind of health liquor and its manufacture craft |
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Application publication date: 20180605 |