CN103202478B - Health protection food for improving sleepy quality and preparation method thereof - Google Patents
Health protection food for improving sleepy quality and preparation method thereof Download PDFInfo
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- CN103202478B CN103202478B CN201310159071.1A CN201310159071A CN103202478B CN 103202478 B CN103202478 B CN 103202478B CN 201310159071 A CN201310159071 A CN 201310159071A CN 103202478 B CN103202478 B CN 103202478B
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Abstract
The invention discloses a health protection food for improving the sleepy quality and a preparation method thereof. The health protection food consists of American ginseng, lucid ganoderma, schisandra chinensis, fuling and spina date seed and is prepared by extracting and powdering the American ginseng, the lucid ganoderma, the schisandra chinensis, the fuling and the spina date seed, preparing American ginseng powder, mixing the raw materials, and metering, filling and packaging the mixture. The health protection food produced by the technology can be safely taken, has an obvious health protection effect, is low in industrial production cost and has extremely high market development and application prospect.
Description
Technical field
The invention belongs to field of health care food, be specifically related to a kind of health food that improves sleep and preparation method thereof.
Background technology
Sleep refers to inertia and the non-reactiveness of recurrence, and during sleep, level of consciousness reduces or disappears, and most physiological activity and reaction enter inert condition.By sleep, make tired nerve cell recover normal physiological function, spirit and muscle power are restored.During sleep, the anterior pituitary growth hormone secretion obviously increases, and is conducive to promote body growth, and makes the synthetic increase of nucleoprotein, is conducive to the storage of memory.
Sleep-disorder refers to the abnormal of amount of sleep or some clinical symptoms occurs when sleep, reduces too much somnambulism etc. as slept.Insomnia is common sleep-disorder.Insomnia can be divided into: the 1. insomnia due to mental element: stress, anxiety, fear, excitement etc. cause of short duration insomnia, are mainly and fall asleep difficult and easily wake up with a start, and after mental element is removed, insomnia can improve.The existing early awakening of the insomnia multilist of depression or sleep are not dark.Mania shows the difficulty egersis even whole night of falling asleep.Schizophrenia is subject to vainly hope to affect can show difficulty falling asleep or sleep not dark; 2. the insomnia that Physical factors causes: the pain that various physical diseases cause, sufferings, nasal obstruction, expiratory dyspnea, asthma, cough, frequent micturition, feel sick, vomiting, abdominal distension, diarrhoea, palpitaition etc. all can cause fall asleep difficulty and sleep not dark; 3. physiologic factor: due to the change of living and working environment and just to strange land, unused environment, drink strong tea coffee etc. can cause insomnia, have a sleepless night and can improve after short-term regulation.The insomnia that also has the medicine factor to cause.
The today day by day increased in knowledge information blast, competitive spirit, the modern does not require mental skill nowhere.Many people feel " unable to do what one wishes ", insomnia, headache, fidgety, depressed etc.If the people often, in nervous or melancholy state, is easy to cause " overstrain one's nerves ", cause brainfag.The brainfag phenomenon is the gesture of rapid spread in city, becomes and threatens the particularly healthy Silent Killer of the elderly of people.
Do not have enough sleep, have a sleepless night, reach the immunologic function decline that brainfag can cause whole body, easily suffer from the communicable diseases such as cold.If, for a long time in the brainfag state, can not correct in time, just can cause the brain decline, cause the serious encephalopathics such as dementia, encephalatrophy.
Formula material of the present invention has American Ginseng, glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed.Being the state food drugs administration approved has and improves the raw material that sleep function is commonly used.Can supplement the required nutriment of brain, promote the brain cell metabolism, improve microcirculation, the disorder of regulating plant nervous function, the effect of performance relieving mental strain and helping sleep, brain-nourishing intelligence-benefiting.
Summary of the invention
The object of the present invention is to provide a kind of health food that improves sleep and preparation method thereof.This technique makes product and not only takes safety, has significant health-care efficacy, and industrial production cost is low, and good market development application prospect is arranged.
For achieving the above object, the present invention adopts following technical scheme:
A kind of composition and mass fraction of raw material of the health food that improves sleep: American Ginseng 9%-11%, glossy ganoderma 24%-26%, fruit of Chinese magnoliavine 19%-21%, Poria cocos 29%-31%, spina date seed 14%-16%.
The method for preparing the health food of improvement sleep as above comprises the following steps:
(1) glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material lixiviate powder process
Press the raw material proportioning, the glossy ganoderma of selecting through quality standard check, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material soaking in the purifying waste water of 10 times of weight 1 hour, be heated to 100 ℃ with multi-function extractor, lixiviate 3 hours, and 100 orders filter to obtain a leaching liquor; Add purifying waste water of 8 times of weight in filter residue, under same extraction temperature, lixiviate is 2 hours, obtains the secondary leaching liquor again; Twice leaching liquor merged and carry out reduced pressure concentration, temperature 65-75 ℃, pressure 0.06-0.08 MPa, time 3-4 hour, be condensed into thick medicinal extract, relative density 1.25-1.30; Become dry extract through vacuum drying again, temperature 65-75 ℃, pressure 0.06-0.08 MPa, time 3-4 hour; Dry extract, through pulverizing, is crossed 80 mesh sieves and is become extract powder standby;
(2) ginseng powder preparation
American Ginseng is through selected, after water is cleaned, in 60-80 ℃ of oven dry, time 3-4h; Through pulverizing, cross 80 mesh sieves, weighing and bagging is standby;
(3) allotment mixes
Press formulation ratio in 100,000 grades of air cleaning workshops, glossy ganoderma prepared by weighing step (1), the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material extract powder, with ginseng powder mixing and stirring prepared by step (2), standby;
(4) metering is filled, is packed
In 100,000 grades of air cleaning workshops, by the raw material of step (3) with automatic capsule machine filled capsules, polishing, packing;
(5) product inspection, warehouse-in
According to GMP, require finished product is carried out to every check mensuration, warehouse-in up to specification.
Remarkable advantage of the present invention is:
(1) raw materials for production of the present invention are comprised of American Ginseng, glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed.These raw materials are the treasure of motherland's medical science for prevent disease, health care.
(2) this reasonable science of filling a prescription, be rich in the bioactivators such as polysaccharide, panaxoside, B same clan vitamin, trace element.Through results of animal, show: the per os gavage is to this product of mouse after 30 days, carry out the yellow Jackets experiment length of one's sleep and yellow Jackets sub-threshold dose hypnosis experiment, experimental result is all positive, and, without obviously directly sleep effect, illustrates that product of the present invention has the effect that improves sleep function.
(3) production Technology of the present invention has reached advanced international level.This technique convenient operation, can realize that industrialization produces continuously, therefore production cost is low.
The specific embodiment
embodiment 1
A kind of composition and mass fraction of raw material of the health food that improves sleep: American Ginseng 9%, glossy ganoderma 26%, the fruit of Chinese magnoliavine 19%, Poria cocos 31%, spina date seed 15%.
The method for preparing the health food of improvement sleep as above comprises the following steps:
(1) glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material lixiviate powder process
Press the raw material proportioning, the glossy ganoderma of selecting through quality standard check, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material soaking in the purifying waste water of 10 times of weight 1 hour, be heated to 100 ℃ with multi-function extractor, lixiviate 3 hours, and 100 orders filter to obtain a leaching liquor; Add purifying waste water of 8 times of weight in filter residue, under same extraction temperature, lixiviate is 2 hours, obtains the secondary leaching liquor again; Twice leaching liquor merged and carry out reduced pressure concentration, 65 ℃ of temperature, pressure 0.06MPa, 4 hours time, be condensed into thick medicinal extract, relative density 1.25; Become dry extract through vacuum drying again, 65 ℃ of temperature, pressure 0.06 MPa, time 4 hours; Dry extract, through pulverizing, is crossed 80 mesh sieves and is become extract powder standby;
(2) ginseng powder preparation
American Ginseng is through selected, after water is cleaned, in 60 ℃ of oven dry, time 4h; Through pulverizing, cross 80 mesh sieves, weighing and bagging is standby;
(3) allotment mixes
Press formulation ratio in 100,000 grades of air cleaning workshops, glossy ganoderma prepared by weighing step (1), the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material extract powder, with ginseng powder mixing and stirring prepared by step (2), standby;
(4) metering is filled, is packed
In 100,000 grades of air cleaning workshops, by the raw material of step (3) with automatic capsule machine filled capsules, polishing, packing;
(5) product inspection, warehouse-in
According to GMP, require finished product is carried out to every check mensuration, warehouse-in up to specification.
embodiment 2
A kind of composition and mass fraction of raw material of the health food that improves sleep: American Ginseng 10%, glossy ganoderma 24%, the fruit of Chinese magnoliavine 21%, Poria cocos 29%, spina date seed 16%.
The method for preparing the health food of improvement sleep as above comprises the following steps:
(1) glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material lixiviate powder process
Press the raw material proportioning, the glossy ganoderma of selecting through quality standard check, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material soaking in the purifying waste water of 10 times of weight 1 hour, be heated to 100 ℃ with multi-function extractor, lixiviate 3 hours, and 100 orders filter to obtain a leaching liquor; Add purifying waste water of 8 times of weight in filter residue, under same extraction temperature, lixiviate is 2 hours, obtains the secondary leaching liquor again; Twice leaching liquor merged and carry out reduced pressure concentration, 75 ℃ of temperature, pressure 0.08 MPa, 3 hours time, be condensed into thick medicinal extract, relative density 1.30; Become dry extract through vacuum drying again, 75 ℃ of temperature, pressure 0.08 MPa, time 3 hours; Dry extract, through pulverizing, is crossed 80 mesh sieves and is become extract powder standby;
(2) ginseng powder preparation
American Ginseng is through selected, after water is cleaned, in 80 ℃ of oven dry, time 3h; Through pulverizing, cross 80 mesh sieves, weighing and bagging is standby;
(3) allotment mixes
Press formulation ratio in 100,000 grades of air cleaning workshops, glossy ganoderma prepared by weighing step (1), the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material extract powder, with ginseng powder mixing and stirring prepared by step (2), standby;
(4) metering is filled, is packed
In 100,000 grades of air cleaning workshops, by the raw material of step (3) with automatic capsule machine filled capsules, polishing, packing;
(5) product inspection, warehouse-in
According to GMP, require finished product is carried out to every check mensuration, warehouse-in up to specification.
embodiment 3
A kind of composition and mass fraction of raw material of the health food that improves sleep: American Ginseng 10%, glossy ganoderma 25%, the fruit of Chinese magnoliavine 20%, Poria cocos 30%, spina date seed 15%.
The method for preparing the health food of improvement sleep as above comprises the following steps:
(1) glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material lixiviate powder process
Press the raw material proportioning, the glossy ganoderma of selecting through quality standard check, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material soaking in the purifying waste water of 10 times of weight 1 hour, be heated to 100 ℃ with multi-function extractor, lixiviate 3 hours, and 100 orders filter to obtain a leaching liquor; Add purifying waste water of 8 times of weight in filter residue, under same extraction temperature, lixiviate is 2 hours, obtains the secondary leaching liquor again; Twice leaching liquor merged and carry out reduced pressure concentration, temperature 70 C, pressure 0.07 MPa, 3.5 hours time, be condensed into thick medicinal extract, relative density 1.28; Become dry extract through vacuum drying again, temperature 70 C, pressure 0.07 MPa, time 3.5 hours; Dry extract, through pulverizing, is crossed 80 mesh sieves and is become extract powder standby;
(2) ginseng powder preparation
American Ginseng is through selected, after water is cleaned, in 70 ℃ of oven dry, time 3.5h; Through pulverizing, cross 80 mesh sieves, weighing and bagging is standby;
(3) allotment mixes
Press formulation ratio in 100,000 grades of air cleaning workshops, glossy ganoderma prepared by weighing step (1), the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material extract powder, with ginseng powder mixing and stirring prepared by step (2), standby;
(4) metering is filled, is packed
In 100,000 grades of air cleaning workshops, by the raw material of step (3) with automatic capsule machine filled capsules, polishing, packing;
(5) product inspection, warehouse-in
According to GMP, require finished product is carried out to every check mensuration, warehouse-in up to specification.
embodiment 4
Through results of animal, show: the per os gavage is to this product of mouse after 30 days, carry out the yellow Jackets experiment length of one's sleep and yellow Jackets sub-threshold dose hypnosis experiment, experimental result is all positive, and, without obviously directly sleep effect, illustrates that product of the present invention has the effect that improves sleep function.
The foregoing is only preferred embodiment of the present invention, all equalizations of doing according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.
Claims (1)
1. a preparation method who improves the health food of sleep, is characterized in that: the composition of raw material and mass fraction: American Ginseng 10%, glossy ganoderma 25%, the fruit of Chinese magnoliavine 20%, Poria cocos 30%, spina date seed 15%;
The preparation method comprises the following steps:
(1) glossy ganoderma, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material lixiviate powder process
Press the raw material proportioning, the glossy ganoderma of selecting through quality standard check, the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material soaking in the purifying waste water of 10 times of weight 1 hour, be heated to 100 ℃ with multi-function extractor, lixiviate 3 hours, and 100 orders filter to obtain a leaching liquor; Add purifying waste water of 8 times of weight in filter residue, under same extraction temperature, lixiviate is 2 hours, obtains the secondary leaching liquor again; Twice leaching liquor merged and carry out reduced pressure concentration, temperature 65-75 ℃, pressure 0.06-0.08 MPa, time 3-4 hour, be condensed into thick medicinal extract, relative density 1.25-1.30; Become dry extract through vacuum drying again, temperature 65-75 ℃, pressure 0.06-0.08 MPa, time 3-4 hour; Dry extract, through pulverizing, is crossed 80 mesh sieves and is become extract powder standby;
(2) ginseng powder preparation
American Ginseng is through selected, after water is cleaned, in 60-80 ℃ of oven dry, time 3-4h; Through pulverizing, cross 80 mesh sieves, weighing and bagging is standby;
(3) allotment mixes
Press formulation ratio in 100,000 grades of air cleaning workshops, glossy ganoderma prepared by weighing step (1), the fruit of Chinese magnoliavine, Poria cocos, spina date seed raw material extract powder, with ginseng powder mixing and stirring prepared by step (2), standby;
(4) metering is filled, is packed
In 100,000 grades of air cleaning workshops, by the raw material of step (3) with automatic capsule machine filled capsules, polishing, packing;
(5) product inspection, warehouse-in
According to GMP, require finished product is carried out to every check mensuration, warehouse-in up to specification.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310159071.1A CN103202478B (en) | 2013-05-03 | 2013-05-03 | Health protection food for improving sleepy quality and preparation method thereof |
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| CN201310159071.1A CN103202478B (en) | 2013-05-03 | 2013-05-03 | Health protection food for improving sleepy quality and preparation method thereof |
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| CN103202478A CN103202478A (en) | 2013-07-17 |
| CN103202478B true CN103202478B (en) | 2014-01-08 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104432000A (en) * | 2013-09-18 | 2015-03-25 | 中国医学科学院药用植物研究所海南分所 | Sleep improving health-care food and preparation method thereof |
| CN105011129A (en) * | 2014-04-29 | 2015-11-04 | 赛珂睿德生物医药科技(上海)有限公司 | Functional food with sleep improving effect |
| CN104013691A (en) * | 2014-06-20 | 2014-09-03 | 苏州法莫生物技术有限公司 | Granule with sleep improvement effect |
| CN104223066A (en) * | 2014-09-02 | 2014-12-24 | 上海焦点生物技术有限公司 | Traditional Chinese medicine composition for improving sleeping |
| CN107569547A (en) * | 2017-08-25 | 2018-01-12 | 广州百翠原绿色农产品发展有限公司 | A kind of ganoderma lucidum improves Chinese medicine composition of sleep and preparation method thereof |
| CN107596081A (en) * | 2017-11-09 | 2018-01-19 | 江西仙芝来生物科技有限公司 | A kind of Ganoderma lucidum for improving insomnia and preparation method thereof |
| CN116144446A (en) * | 2021-11-19 | 2023-05-23 | 泸州老窖股份有限公司 | Health care wine for improving sleep function |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528173A (en) * | 2003-10-20 | 2004-09-15 | 中国农业科学院蜜蜂研究所 | Royal jelly composition with improved sleep function |
| CN101559139A (en) * | 2008-04-14 | 2009-10-21 | 北京汉潮联创中药科技有限公司 | Prescription of pure traditional Chinese medicine preparation for preventing and curing neurasthenia insomnia and preparation method thereof |
| CN101703622A (en) * | 2009-09-17 | 2010-05-12 | 杭州六易科技有限公司 | Preparation method of buccal tablet for improving sleeping |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20040185118A1 (en) * | 2003-03-19 | 2004-09-23 | Katsumichi Matsushige | Health food for good sleep |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528173A (en) * | 2003-10-20 | 2004-09-15 | 中国农业科学院蜜蜂研究所 | Royal jelly composition with improved sleep function |
| CN101559139A (en) * | 2008-04-14 | 2009-10-21 | 北京汉潮联创中药科技有限公司 | Prescription of pure traditional Chinese medicine preparation for preventing and curing neurasthenia insomnia and preparation method thereof |
| CN101703622A (en) * | 2009-09-17 | 2010-05-12 | 杭州六易科技有限公司 | Preparation method of buccal tablet for improving sleeping |
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