CN101559139A

CN101559139A - Prescription of pure traditional Chinese medicine preparation for preventing and curing neurasthenia insomnia and preparation method thereof

Info

Publication number: CN101559139A
Application number: CNA2008101039982A
Authority: CN
Inventors: 李冠祥; 张伟; 李正; 张传吉
Original assignee: BEIJING HANCHAO LIANCHUANG TRADITIONAL CHINESE MEDICINE TECHNOLOGY Co Ltd
Current assignee: BEIJING HANCHAO LIANCHUANG TRADITIONAL CHINESE MEDICINE TECHNOLOGY Co Ltd
Priority date: 2008-04-14
Filing date: 2008-04-14
Publication date: 2009-10-21

Abstract

The invention relates to a prescription of a pure traditional Chinese medicine preparation for preventing and curing neurasthenia insomnia and a preparation method thereof, belonging to a pure traditional Chinese medicine preparation, in particular to a pure traditional Chinese preparation for preventing and curing the neurasthenia insomnia. The prescription of the pure traditional Chinese medicine preparation contains the following components according to the parts by weight: 25-30 of tuner fleeceflower stem, 25-30 of Dangshen, 25-30 of shizandra berry, 15-20 of wild jujube seed (prepared), 15-20 of medlar, 5-10 of dried orange peel and 5-10 of glossy ganoderma. The invention has the efficacies of relieving heart and maintaining spirit, supplementing qi and promoting the production of body fluid, and smoothening lever and relieving depression.

Description

Pure Chinese medicinal preparation prescription of a kind of prevention and treatment insomnia disorder due to neurasthenia and preparation method thereof

Background technology

The quickening day by day of modern life rhythm and the multiple complicated reasons such as continuous increase of social competition's pressure, cause the existing crowd in the present whole world to suffer from the insomnia obstacle that the neurasthenia causes to some extent up to about 30%, among the crowd, adult insomnia rate is unexpectedly up to more than 57% in this section.Multiple symptoms such as neurasthenia's induced insomnia disease often is attended by again that thinking is in a trance, mental retard, sensitivity and lucidity difference and hypomnesis and dizziness, headache, weak, cardiopalmus and insomnia.

Emotion symptom such as the neurasthenia is easily excited and fatiguability with spirit, be nervous, irritated and emotional, irritability and tonic muscle pain and sleep disorder are a kind of neurosis of principal character.In recent years, this disease had the trend that increases year by year, and this greatly reduces patient's quality of life undoubtedly.Though the patient seeks the doctor everywhere and sees a doctor, because in clinical, the most of diagnoses and treatment that adopts " judging the case as it stands " of doctor trained in Western medicine, and most of traditional Chinese medical science can not be implemented correct dialectical treatment, therefore, the patient often is difficult to obtain desirable therapeutic.

Often run into the patient of many so-called neurasthenias and insomnia obstacle thereof in clinical, in fact these patients are not real neurasthenia, insomnia disfunction, but a kind of organic disease causes etc. as, cerebral arteriosclerosis hyperfunction by thyroid, anemia, hypertension, depression etc.Therefore, this neurasthenia of diagnosis and treatment and insomnia disfunction thereof can not be judged the case as it stands, must comprehensive multiple factor and just can make in conjunction with the chemical examination detection means of necessity and to make a definite diagnosis.Patent drug of the present invention is exactly on the basis of comprehensive multiple factor and a kind of science of developing through a large amount of clinical verifications is treated the pure Chinese medicinal preparation that insomnia disorder due to neurasthenia also can improve immunity, health invigorating, nourishing nerve.

Summary of the invention

The purpose of this invention is to provide novel pure Chinese medicinal preparation prescription of a kind of prevention and treatment neurasthenia aypnia disease and preparation method thereof, medicine by this formulation can effectively prevent and treat insomnia disorder due to neurasthenia, will greatly improve many drawback problems of present Chinese and western medicine diagnosis and treatment primary disease.

Patented technology medicine of the present invention can scientificlly and effectively greatly improve many drawback problems that present Chinese and western medicine diagnosis and treatment insomnia disorder due to neurasthenia field exists, be because patented technology medicine of the present invention is a kind of natural pure Chinese medicinal preparation, this pure Chinese medicinal preparation is realized by following practicable technical scheme: get Caulis Polygoni Multiflori 25-30 part, Radix Codonopsis 25-30 part, Fructus Schisandrae Chinensis 25-30 part, Semen Ziziphi Spinosae (ripe) 15-20 part, Fructus Lycii 15-20 part, Pericarpium Citri Reticulatae 5-10 part, 7 flavor medicine preparations such as Ganoderma 5-10 part, 1/2 of Radix Codonopsis wherein is ground into coarse powder, add that 80% ethanol is wet to be soaked 1 hour, reflux, extract, 2 times, the 1st time 2 hours, the 2nd time 1 hour, merge extractive liquid, is concentrated into the thick paste shape; Get all the other preparation medicines and decoct 2 times, each 1 hour, filter, merging filtrate is concentrated into the thick paste shape.Above-mentioned thick paste is merged, and drying is ground into fine powder, incapsulates interior or adds relevant adjuvant to make granule, or be made into other dosage form.This drug ratio is reasonable, onset rapidly, steady quality, taking convenience, the effect of tranquilizing by nourishing the heart, tonifying QI to produce body fluid, soothing liver-QI for relieving depression is arranged.

The specific embodiment:

This specific embodiment is by 7 flavor medicine preparations such as Caulis Polygoni Multiflori 25-30 part, Radix Codonopsis 25-30 part, Fructus Schisandrae Chinensis 25-30 part, Semen Ziziphi Spinosae (ripe) 15-20 part, Fructus Lycii 15-20 part, Pericarpium Citri Reticulatae 5-10 part, Ganoderma 5-10 part, 1/2 of Radix Codonopsis wherein is ground into coarse powder, add that 80% ethanol is wet to be soaked 1 hour, reflux, extract, 2 times, the 1st time 2 hours, the 2nd time 1 hour, merge extractive liquid, was concentrated into the thick paste shape; Get all the other preparation medicines and decoct 2 times, each 1 hour, filter, merging filtrate is concentrated into the thick paste shape.Above-mentioned thick paste is merged, and drying is ground into fine powder, incapsulates interior or adds relevant adjuvant to make granule, or be made into other dosage form.This drug ratio is reasonable, onset rapidly, steady quality, taking convenience, the effect of tranquilizing by nourishing the heart, tonifying QI to produce body fluid, soothing liver-QI for relieving depression is arranged.Press practice of pharmacy, also pure Chinese medicine capsule of the present invention and granular preparation should be made into the various clinical pharmaceutical dosage form, comprise the dosage form of various oral formulations or parenterai administration approach.Described oral formulations can be divided into any in the middle of tablet, granule, pill, capsule, suspensoid, drop pill, the oral fluid agent etc.; Described parenterai administration dosage form can be divided into a kind of in the middle of injection, suppository, aerosol or the subcutaneous administration dosage form etc.

Patent pure Chinese medicinal preparation of the present invention, main pharmacodynamics research before clinical shows that it has: feel at ease to repose, the effect of supplementing QI for promoting the production of body fluid, soothing liver-QI for relieving depression.Above-mentioned effect is reached a conclusion by zoopery:

1, this medicine can reduce the mice autonomic activities, prolong the length of one's sleep, and the reaction of fainting from fear due to its antagonism galvanic shock and the chemical is similar to stable class drug effect, and the effect of analgesia and relaxed muscle is still arranged.

2, this medicine can produce the blood vessel dilating effect to cardiovascular system.The Canis familiaris L. Mesenteric artery contraction of exsomatizing there is inhibitory action; Exsomatize rat heart and anesthesia Canis familiaris L. arteria coronaria had the effect of the arteries and veins of increasing blood flow.

3, this medicine can promote the formation of laboratory mice hepatic glycogen, and the mouse liver cell protein synthesis is obviously strengthened, and carbohydrate metabolism is strengthened.Simultaneously, facilitation is arranged, the lymphoblast growing amount is increased, and can promote the immunologic function of spleen lymphocyte DNA is synthetic.

This medicine has also been obtained the curative effect of " eliminate the insomnia obstacle, regulate function of nervous system, grow nerve injury, the enhancing brain vigor repaiied " clinically.

Claims

1, pure Chinese medicinal preparation prescription of a kind of prevention and treatment insomnia disorder due to neurasthenia and preparation method thereof is characterized in that it is made up of Caulis Polygoni Multiflori 25-30 part, Radix Codonopsis 25-30 part, Fructus Schisandrae Chinensis 25-30 part, Semen Ziziphi Spinosae (ripe) 15-20 part, Fructus Lycii 15-20 part, Pericarpium Citri Reticulatae 5-10 part, Ganoderma 5-10 part.The present invention have feel at ease to repose, the effect of supplementing QI for promoting the production of body fluid, soothing liver-QI for relieving depression.

2, pure Chinese medicinal preparation prescription of a kind of prevention and treatment insomnia disorder due to neurasthenia and preparation method thereof, it is characterized in that its concrete manufacture method is for getting 7 flavor medicine preparations such as Caulis Polygoni Multiflori 25-30 part, Radix Codonopsis 25-30 part, Fructus Schisandrae Chinensis 25-30 part, Semen Ziziphi Spinosae (ripe) 15-20 part, Fructus Lycii 15-20 part, Pericarpium Citri Reticulatae 5-10 part, Ganoderma 5-10 part, 1/2 of Radix Codonopsis wherein is ground into coarse powder, add that 80% ethanol is wet to be soaked 1 hour, reflux, extract, 2 times, the 1st time 2 hours, the 2nd time 1 hour, merge extractive liquid, is concentrated into the thick paste shape; Get all the other preparation medicines and decoct 2 times, each 1 hour, filter, merging filtrate is concentrated into the thick paste shape.Above-mentioned thick paste is merged, and drying is ground into fine powder, incapsulates interior or adds relevant adjuvant to make granule, or be made into other dosage form.This drug ratio is reasonable, onset rapidly, steady quality, taking convenience, the effect of tranquilizing by nourishing the heart, tonifying QI to produce body fluid, soothing liver-QI for relieving depression is arranged.