CN108079060A - It is a kind of to blend together preparation and preparation method for Internal Medicine-Cardiovascular Dept. clinic - Google Patents

It is a kind of to blend together preparation and preparation method for Internal Medicine-Cardiovascular Dept. clinic Download PDF

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Publication number
CN108079060A
CN108079060A CN201810091631.7A CN201810091631A CN108079060A CN 108079060 A CN108079060 A CN 108079060A CN 201810091631 A CN201810091631 A CN 201810091631A CN 108079060 A CN108079060 A CN 108079060A
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parts
preparation
internal medicine
cardiovascular dept
clinic
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杨杰书
李春晓
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Qingdao Central Hospital
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Qingdao Central Hospital
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

Preparation and preparation method are blended together for Internal Medicine-Cardiovascular Dept. clinic the invention discloses a kind of, is made of the raw material of following parts by weight:15 25 parts of selfheal, 30 50 parts of Radix Angelicae Sinensis, 58 parts of ginseng, 10 20 parts of seaweed, 10 15 parts of Radix Glycyrrhizae, 8 15 parts of Radix Salviae Miltiorrhizae, 10 30 parts of Poria cocos, 10 30 parts of cassia twig, 20 30 parts of scutellaria, 4 12 parts of safflower;Further include suitable brown sugar;Preparation method is:Choose Chinese medicine material described above, screen decontamination, add in the water of 3~5 times of amounts, impregnate 2~3 it is small when after, be boiled by fire after ten minutes, change small fire and decoct 40~50 minutes, liquid is made, after the liquid of gained is cooled down, filtering is removed slag, reserved filtrate;According to 1 in filtrate:4 ratio adds in brown sugar, and small fire, which decocts to be made after ten minutes, blendes together preparation;Therapeutic effect of the present invention is good, and without any side effects and uneasy to recur, taste is slightly sweet, convenient.

Description

It is a kind of to blend together preparation and preparation method for Internal Medicine-Cardiovascular Dept. clinic
Technical field
It is specifically a kind of to be mixed for Internal Medicine-Cardiovascular Dept. to be clinical the present invention relates to cardiovascular drugs technical field Into preparation and preparation method.
Background technology
Angiocardiopathy, also known as circulation system disease, are a series of diseases for being related to the circulatory system, the circulatory system refers to people Internal hemophoric organ and tissue, can be subdivided into it is acute and chronic, it is typically related with artery sclerosis.Cardiovascular disease There are many disease of disease, common are coronary heart disease, hypertension, angina cordis, heart disease infarct etc..
At present, about 3,000,000 people die of angiocardiopathy every year in China, account for the 40% of whole causes of death, are China The number one killer of resident.Clinically, western medical treatment mainly has the drugs such as the agent of expansion blood vessel, depressor and anti-platelet aggregation agent, These medicine side effects are larger, and long-time service can bring blood vessel and human organ different degrees of injury.In recent years, traditional Chinese medicine is prevented Angiocardiopathy research obtains many-sided progress, as activating blood and resolving stasis and treating coronary disease and angina pectoris, qi and activate blood circulation or supplementing qi and nourishing yin are lived Blood treatment acute myocardial infarction or cardiac insufficiency, supplementing qi and invigorating vasculum temperature sun treat slow arrhythmia, QI invigorating is established the yang function, and poison is controlled Restenosis etc., all shows effect certainly after treatment vital myocarditis, vital energy regualting and blood circulation-promoting prevention coronary heart disease interventional therapy.The traditional Chinese medical science exists In terms of many diseases for preventing cardiovascular system, certain advantage is also shown.
The advantage of TCM prevention and cure cardiovascular disease how is given full play to, further improves clinical efficacy, is modern Chinese medicine clinic The problem of need to further inquiring into.
The content of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of clinical for Internal Medicine-Cardiovascular Dept. Preparation and preparation method are blended together, preparation method is simple, at low cost, and therapeutic effect is good, without any side effects and uneasy to recur, food With conveniently.
To achieve the above object, the technical solution adopted by the present invention is:
It is a kind of to blend together preparation for Internal Medicine-Cardiovascular Dept. clinic, it is made of the raw material of following parts by weight:Selfheal 15-25 Part, 30-50 parts of Radix Angelicae Sinensis, 5-8 parts of ginseng, 10-20 parts of seaweed, 10-15 parts of Radix Glycyrrhizae, 8-15 parts of Radix Salviae Miltiorrhizae, 10-30 parts of Poria cocos, cassia twig 10-30 parts, 20-30 parts of scutellaria, 4-12 parts of safflower;Further include suitable brown sugar.
Further, it is described it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, be made of the raw material of following parts by weight:Summer 15 parts of withered grass, 30 parts of Radix Angelicae Sinensis, 5 parts of ginseng, 10 parts of seaweed, 10 parts of Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizae, 10 parts of Poria cocos, 10 parts of cassia twig, scutellaria 20 Part, 4 parts of safflower;Further include suitable brown sugar.
Further, it is described it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, be made of the raw material of following parts by weight:Summer 25 parts of withered grass, 50 parts of Radix Angelicae Sinensis, 8 parts of ginseng, 20 parts of seaweed, 15 parts of Radix Glycyrrhizae, 15 parts of Radix Salviae Miltiorrhizae, 30 parts of Poria cocos, 30 parts of cassia twig, scutellaria 30 Part, 12 parts of safflower;Further include suitable brown sugar.
Further, it is described it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, be made of the raw material of following parts by weight:Summer 20 parts of withered grass, 40 parts of Radix Angelicae Sinensis, 7 parts of ginseng, 15 parts of seaweed, 12 parts of Radix Glycyrrhizae, 10 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 20 parts of cassia twig, scutellaria 25 Part, 8 parts of safflower;Further include suitable brown sugar.
It is a kind of to blend together formulation preparation method for Internal Medicine-Cardiovascular Dept. clinic, be specifically:It is former to choose Chinese medicine described above Material, screen decontamination, add in 3~5 times amount water, impregnate 2~3 it is small when after, be boiled by fire after ten minutes, change small fire decoct 40~ 50 minutes, liquid is made, after the liquid of gained is cooled down, filtering is removed slag, reserved filtrate;According to 1 in filtrate:4 ratio adds in Brown sugar, small fire, which decocts to be made after ten minutes, blendes together preparation.
The pharmacological effect of various raw materials is in the present invention:
Radix Angelicae Sinensis:Replenishing and activating blood, anti-arrhythmia, reducing blood lipid and antiatherosclerosis.
Selfheal:It relieves inflammation or internal heat, improving eyesight, dissipating bind, detumescence.For red eye, swell pain, mesh pearl nyctalgia, dizziness of having a headache, scrofula, goiter and tumor, Swelling and pain, Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension, hyperglycaemia, hyperlipidemia and high blood glue.
Radix Glycyrrhizae:It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.
Ginseng:Suitable for adjustment blood pressure, recover cardiac function, neurasthenia and the diseases such as in poor health, also there is eliminating the phlegm, strong Stomach, diuresis, excitement and other effects.
Radix Salviae Miltiorrhizae:Promoting blood circulation, nourishing blood and tranquilization, cool blood detumescence, to strengthen myocardial contractive power, improve cardiac function, expansion Coronary artery and peripheral blood vessel, the reparation and regeneration that promote tissue.
Seaweed:Nature and flavor are salty-cold, have effects that heat-clearing, softening and resolving hard mass.
Scutellaria:It is bitter, cold in nature, there are heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis and other effects.Cure mainly warm heat disease, upper breathing The diseases such as road infection, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, carbuncle swells furuncle sore.
Poria cocos:Cure mainly oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Cassia twig:Taste acrid, sweet, warm enter lung, the heart, bladder warp, are to cure mainly the common drugs for dispelling internal cold of interior cold, have complement sun, logical blood The effect of arteries and veins, warming spleen and stomach.
Safflower:Invigorate blood circulation, removing blood stasis and analgesics, contribute to controlling through closing, dysmenorrhoea, lochia, chest impediment and cardialgia, stasis of blood, Chest side of body shouting pain, traumatic injury, sore swell and ache curative curative effect.
With the above structure, beneficial effects of the present invention are:Preparation method of the present invention is simple, at low cost, therapeutic effect Good, without any side effects and uneasy to recur, taste is slightly sweet, convenient.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with specific embodiment The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are only to explain the present invention, and It is not used in the restriction present invention.
Embodiment 1
It is a kind of to blend together preparation for Internal Medicine-Cardiovascular Dept. clinic, it is made of the raw material of following parts by weight:15 parts of selfheal, when Return 30 parts, 5 parts of ginseng, 10 parts of seaweed, 10 parts of Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizae, 10 parts of Poria cocos, 10 parts of cassia twig, 20 parts of scutellaria, 4 parts of safflower; Further include suitable brown sugar.
Embodiment 2
It is a kind of to blend together preparation for Internal Medicine-Cardiovascular Dept. clinic, it is made of the raw material of following parts by weight:25 parts of selfheal, when Return 50 parts, 8 parts of ginseng, 20 parts of seaweed, 15 parts of Radix Glycyrrhizae, 15 parts of Radix Salviae Miltiorrhizae, 30 parts of Poria cocos, 30 parts of cassia twig, 30 parts of scutellaria, safflower 12 Part;Further include suitable brown sugar.
Embodiment 3
It is a kind of to blend together preparation for Internal Medicine-Cardiovascular Dept. clinic, it is made of the raw material of following parts by weight:20 parts of selfheal, when Return 40 parts, 7 parts of ginseng, 15 parts of seaweed, 12 parts of Radix Glycyrrhizae, 10 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 20 parts of cassia twig, 25 parts of scutellaria, 8 parts of safflower; Further include suitable brown sugar.
The preparation method of above example is:Chinese medicine material described above is chosen, screens decontamination, adds in 3~5 times of amounts Water, impregnate 2~3 it is small when after, be boiled by fire after ten minutes, change small fire decoct 40~50 minutes, be made liquid, by the medicine of gained After liquid cooling, filtering is removed slag, reserved filtrate;According to 1 in filtrate:4 ratio adds in brown sugar, and small fire decoction is made after ten minutes Blend together preparation.
The usage of present embodiment is:It takes within one day 2 times, is 10ml each taking dosage once in the morning and once at night.
Model case:
Patient Zhang, man, 65 years old, worker, with hypertension 5 years, after being engaged in physical taskwork, dizziness of having a headache, expiratory dyspnea, Palpitation and short breath, paroxysmal angina pectoris take the drug of decompression, do not improve significantly always, and with certain drug according to Rely, after taking present embodiment 1 month, there is apparent improvement, after taking 2 months, substantially eliminate symptom, and it is not multiple always Hair.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned exemplary embodiment, Er Qie In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Profit requirement rather than above description limit, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims Variation is included within the present invention.
Moreover, it will be appreciated that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should Using specification as an entirety, the technical solutions in each embodiment can also be properly combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (5)

1. a kind of blend together preparation for Internal Medicine-Cardiovascular Dept. clinic, it is characterised in that:It is made of the raw material of following parts by weight:Summer is withered 15-25 parts careless, 30-50 parts of Radix Angelicae Sinensis, 5-8 parts of ginseng, 10-20 parts of seaweed, 10-15 parts of Radix Glycyrrhizae, 8-15 parts of Radix Salviae Miltiorrhizae, Poria cocos 10-30 Part, 10-30 parts of cassia twig, 20-30 parts of scutellaria, 4-12 parts of safflower;Further include suitable brown sugar.
2. it is according to claim 1 it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, it is characterised in that:Described one kind Preparation is blended together for Internal Medicine-Cardiovascular Dept. clinic, is made of the raw material of following parts by weight:15 parts of selfheal, 30 parts of Radix Angelicae Sinensis, ginseng 5 Part, 10 parts of seaweed, 10 parts of Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizae, 10 parts of Poria cocos, 10 parts of cassia twig, 20 parts of scutellaria, 4 parts of safflower;It further includes suitable Brown sugar.
3. it is according to claim 1 it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, it is characterised in that:Described one kind Preparation is blended together for Internal Medicine-Cardiovascular Dept. clinic, is made of the raw material of following parts by weight:25 parts of selfheal, 50 parts of Radix Angelicae Sinensis, ginseng 8 Part, 20 parts of seaweed, 15 parts of Radix Glycyrrhizae, 15 parts of Radix Salviae Miltiorrhizae, 30 parts of Poria cocos, 30 parts of cassia twig, 30 parts of scutellaria, 12 parts of safflower;It further includes appropriate Brown sugar.
4. it is according to claim 1 it is a kind of for Internal Medicine-Cardiovascular Dept. it is clinical blend together preparation, it is characterised in that:Described one kind Preparation is blended together for Internal Medicine-Cardiovascular Dept. clinic, is made of the raw material of following parts by weight:20 parts of selfheal, 40 parts of Radix Angelicae Sinensis, ginseng 7 Part, 15 parts of seaweed, 12 parts of Radix Glycyrrhizae, 10 parts of Radix Salviae Miltiorrhizae, 20 parts of Poria cocos, 20 parts of cassia twig, 25 parts of scutellaria, 8 parts of safflower;It further includes suitable Brown sugar.
5. a kind of blend together formulation preparation method for Internal Medicine-Cardiovascular Dept. clinic, it is characterised in that:Specific method is:It chooses above-mentioned The Chinese medicine material, screen decontamination, add in 3~5 times amount water, impregnate 2~3 it is small when after, be boiled by fire after ten minutes, change Small fire decocts 40~50 minutes, and liquid is made, and after the liquid of gained is cooled down, filtering is removed slag, reserved filtrate;In filtrate according to 1:4 ratio adds in brown sugar, and small fire, which decocts to be made after ten minutes, blendes together preparation.
CN201810091631.7A 2018-01-30 2018-01-30 It is a kind of to blend together preparation and preparation method for Internal Medicine-Cardiovascular Dept. clinic Pending CN108079060A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085012A (en) * 2006-06-08 2007-12-12 天津天士力制药股份有限公司 Composition containing safflower for treating cardiovascular diseases and its preparation
CN101104048A (en) * 2006-07-14 2008-01-16 黄振华 Compound medicine for pulse generating and treating coronary heart disease
CN103202879A (en) * 2013-04-23 2013-07-17 辽宁中医药大学附属医院 Traditional Chinese medicine composition for treating chronic cardiac failure and preparation method thereof
CN105456390A (en) * 2015-12-17 2016-04-06 夏修菲 Clinical mixed preparation for cardiovascular department and preparation method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085012A (en) * 2006-06-08 2007-12-12 天津天士力制药股份有限公司 Composition containing safflower for treating cardiovascular diseases and its preparation
CN101104048A (en) * 2006-07-14 2008-01-16 黄振华 Compound medicine for pulse generating and treating coronary heart disease
CN103202879A (en) * 2013-04-23 2013-07-17 辽宁中医药大学附属医院 Traditional Chinese medicine composition for treating chronic cardiac failure and preparation method thereof
CN105456390A (en) * 2015-12-17 2016-04-06 夏修菲 Clinical mixed preparation for cardiovascular department and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王汉祥: "《冠心病》", 31 January 1998, 武汉出版社 *

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