CN106620001A - Traditional Chinese medicine for treating diabetic foots and preparation method thereof - Google Patents
Traditional Chinese medicine for treating diabetic foots and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/55—Liquid-liquid separation; Phase separation
Abstract
The invention provides a traditional Chinese medicine for treating diabetic foots and a preparation method thereof. The traditional Chinese medicine comprises the following components in parts by weight: 10-20 parts of milkvetch root, 5-15 parts of prepared rhizoma corydalis, 5-15 parts of motherwort herb, 5-15 parts of peach seed, 10-20 parts of fried white peony root, 5-15 parts of figwort root, 5-15 parts of salvia miltiorrhiza bunge, 5-12 parts of red peony root, 5-15 parts of safflower, 5-12 parts of Szechuan lovage rhizome, and 4-10 parts of costus root; and the components of the traditional Chinese medicine are subjected to soaking and decoction to prepare a traditional Chinese medicine preparation. In the traditional Chinese medicine for treating the diabetic foots, various medicines complement each other, so that the traditional Chinese medicine has the effects of promoting qi circulation to relieve pain, promoting blood circulation to remove blood stasis, warming kidney to nourish yang, and activating collaterals for dehumidification, and is quick in effect of treating the diabetic foots, significant in effect, and small in side effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine and preparation method for treating diabetes.
Background technology
Diabetes（Diabetes mellitus, DM）It is due to internal hypoinsulinism or effect defect
A kind of common endocrine metabolism disease with the metabolic disorder such as sugar, fat, protein as principal character.In recent years, with people
The factors such as growth in the living standard, living-pattern preservation, the incidence of disease rapid development of global diabetes, diabetes are
Jing becomes the common disease of the third-largest serious threat human health after tumour, cardiovascular pathological changes and life.Diabetes sheet
Body not necessarily can cause serious harm, but long-term blood glucose to increase to patient, big blood vessel, capilary be damaged and jeopardize the heart, brain, kidney,
Peripheral nerve, eyes, foot etc., can cause a series of diabetic complication with patient's course advancement.According to the World Health Organization
Statistics, diabetic complication is up to kind more than 100, is to be currently known a kind of most disease of complication.The complications of diabetes are
Affect the quality of life of diabetic and cause diabetic's death chief reason.
The major complications of diabetes have diabetes, diabetic eye diseases, diabetic nephropathy, diabetic neuropathy, sugar
Various diseases such as the sick cardiovascular pathological changes of urine.Wherein, diabetes refer to diabetic under hyperglycaemia environment by artery of lower extremity
Parteriole obturation or the factor collective effect such as skin Microangiopathy and bacterium infection, DPN that hardening causes,
Cause foot numbness, pain, infection, the ulcer even pathology such as gangrene.Diabetes are a kind of serious complication of diabetes, are
Diabetic is disabled, and severe one can cause amputation even threat to life.The lighter only has foot's hypodynia, skin surface ulcer；Moderate
Can there is deeper penetrating ulcer and merge soft tissue inflammation in person；Severe patient merges Soft Tissue Abscess: An Experimental, bone tissue simultaneously in ulcer
Pathology, can notably there is full pin gangrene in toe, heel or front instep circumscribed gangrene.Due to the diabetes course of disease it is long, it is clinical
Performance is different, and along with shortage of the patient to Diabetes Mellitus Knowledge, sense of self-protection is not strong, and patient does not seek medical advice in time, Yi Jilin
Bed doctor also lacks deep understanding and attention to this, additionally, it is domestic also without specific treatment method for the disease, it is simply general western
The of short duration pain relieving relief of symptoms of medicine, though effective in cure must not eradicate, the treatment for causing the disease is still at present a great problem.
The content of the invention
For defect of the prior art, it is an object of the invention to provide a kind of instant effect, effect is significant, Small side effects
Chinese medicine for the treatment of diabetes and preparation method thereof.
The present invention solves technical problem and adopts the following technical scheme that：
The present invention relates to a kind of Chinese medicine for treating diabetes, described Chinese medicine includes each component of following parts by weight：The Radix Astragali
10～20 parts, 5～15 parts of corydalis tuber processed, 5～15 parts of motherwort, 5～15 parts of peach kernel, 10～20 parts of stir-baked RADIX PAEONIAE ALBA, 5～15 parts of radix scrophulariae,
5～15 parts of radix salviae miltiorrhizae, 5～12 parts of the radix paeoniae rubrathe, 5～15 parts of safflower, 5～12 parts of Ligusticum wallichii, 4～10 parts of the banksia rose.
Preferably, the Chinese medicine of the treatment diabetes, including each component of following parts by weight：15～20 parts of the Radix Astragali,
8～15 parts of corydalis tuber processed, 8～15 parts of motherwort, 8～15 parts of peach kernel, 10～20 parts of stir-baked RADIX PAEONIAE ALBA, 8～15 parts of radix scrophulariae, radix salviae miltiorrhizae 8～
15 parts, 8～12 parts of the radix paeoniae rubrathe, 8～15 parts of safflower, 5～12 parts of Ligusticum wallichii, 4～10 parts of the banksia rose.
Preferably, the Chinese medicine of the treatment diabetes, including each component of following parts by weight：15 parts of the Radix Astragali, system unit
10 parts recklessly, 13 parts of motherwort, 8 parts of peach kernel, 12 parts of stir-baked RADIX PAEONIAE ALBA, 8 parts of radix scrophulariae, 12 parts of radix salviae miltiorrhizae, 8 parts of the radix paeoniae rubrathe, 10 parts of safflower, Ligusticum wallichii
10 parts, 8 parts of the banksia rose.
Preferably, the Chinese medicine of described treatment diabetes, including each component of following parts by weight：15 parts of the Radix Astragali, system
10 parts of corydalis tuber, 10 parts of motherwort, 10 parts of peach kernel, 12 parts of stir-baked RADIX PAEONIAE ALBA, 10 parts of radix scrophulariae, 10 parts of radix salviae miltiorrhizae, 8 parts of the radix paeoniae rubrathe, 10 parts of safflower,
8 parts of Ligusticum wallichii, 6 parts of the banksia rose.
The present invention also provides the preparation method of the Chinese medicine of the treatment diabetes, and the preparation method is as follows：By each group
Point proportionally it is well mixed, plus 20～30 DEG C of water soaks 20～30min, is put into boiling machine, decocts 40min, filters off the dregs of a decoction,
Liquid is pressed into Chinese herbal medicine bag by 180～200ml/ bags, is obtained final product, it is stored refrigerated to put 0-8 DEG C of refrigerator, it is sooner or later each once, once a bag,
One after each meal.
Preferably, the gross weight of the addition water is 10～12 times of Chinese medicine gross weight.
The present invention also provides another kind of preparation method of the Chinese medicine of the treatment diabetes, and the preparation method is as follows：
After each traditional Chinese medicinal components mixing, the water for adding 8～10 times of Chinese medicine gross weight soaks 0.5～1h, and heating decocts 40～50min, filters
Decoction liquor is obtained, adds initial Chinese medicine gross weight to add 6～8 times of the secondary decoction of water in the dregs of a decoction, decoct 30～40min, filtered
Decoction liquor is obtained, decoction liquor twice is merged and is concentrated into relative density for 1.18～1.25（50-70℃）, add 80～95% second
Alcohol adjusts alcohol content and reaches 50%, stirs evenly, and stands more than 12h, and filtration, filtrate recycling ethanol is concentrated into the thick paste without alcohol taste, subtracts
Pressure is dried to dry extract, adding pharmaceutically acceptable forming agent auxiliary material, such as amylum pregelatinisatum, lactose, dextrin, microcrystalline cellulose,
Magnesium stearate, Sodium Hydroxymethyl Stalcs etc., make Chinese medicine preparation.
Preferably, the Chinese medicine preparation includes granule, capsule, tablet.
The Chinese medicine composition for the treatment of diabetes of the present invention is inventor based on oneself clinical experience and to sugar for many years
Pathogenetic heightened awareness of urine disease, Jing optimizes checking and obtains repeatedly.The pharmacological property of each component of Chinese medicine of the present invention
It is as follows：
The Radix Astragali, sweet, slight bitter, return lung, spleen, kidney channel, with tonifying Qi and lifting yang, invigorating qi for consolidating superficies, promoting blood circulation and removing obstruction in channels, tonifying spleen moistening lung, are promoted the production of body fluid
Quench the thirst, many effects such as promoting pus discharge and tissue regeneration and inducing diuresis for removing edema, the Radix Astragali mainly contains glycoside, polysaccharide, amino acid, trace element and flavones
Deng, can promote organism metabolism, it is antifatigue, strengthen body's immunity, cardiac stimulant, anti-arrhythmia, anti anoxia, protection cardiovascular and cerebrovascular
Etc. various effects.
Corydalis tuber, warm in nature, taste is pungent is bitter, enter the heart, spleen, liver, lung, promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, especially with famous the effect of pain relieving
In generation.Can also be used for each portion's qi stagnation blood stasis of whole body pain, injury from falling down.Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》Middle conclusion corydalis tuber has " living
Four large effects of blood, sharp gas, pain relieving, diuresis ", and praise highly corydalis tuber " can the stagnation of the circulation of vital energy in promoting circulation of blood, stasis in gas, therefore specially control all over the body up and down
All pains ".The traditional Chinese medical science thinks, corydalis tuber is pungent to be dissipated, hardship is let out, Wen Tong, has both entered blood system, and gas point is entered again, gas that can be in promoting circulation of blood, and can be in promoting the circulation of qi
Blood, the smooth blood of gas, no pain by smooth breath.
Motherwort, taste is pungent, hardship, cold nature, enter the heart, liver, bladder warp, with the effect of adjusting the stasis of blood, inducing diuresis to remove edema of invigorating blood circulation, this
Outward, also with the effect to resisting myocardial ischemia, reducing blood viscosity, resisting blood coagulation and protection kidney.
Peach kernel, the sweet flat, bitter of property, enters lung, liver, large intestine channel；There are the blood-breaking row stasis of blood, effect of moisturize laxation；Peach kernel contains many
Nutrient content and bioactivator are planted, its decocting boils agent and extract also has certain antibacterial analgesia, antiallergy, antitumor etc.
Effect.
The root of herbaceous peony, property is bitter, taste acid, cold nature, Return liver, the spleen channel.Cloudy receipts sweat is held back in root of herbaceous peony nourishing blood and liver, pain relieving in delaying.The root of herbaceous peony has
There are the multiple pharmacological effects such as pain relieving, anti-inflammatory, liver protection and multipath suppression of autoimmune responses.
Radix scrophulariae is sweet, bitter, salty；Cold nature.Return lung, stomach, kidney channel.Radix scrophulariae contains alkaloid, carbohydrate, sterol, amino acid（It is left
Rotation asparagine etc.）, aliphatic acid（Mainly oleic acid, leukotrienes, stearic acid）, volatile oil, carrotene and vitamin A class thing
Matter；There is clearing heat and cooling blood, purging intense heat and detonicating, dissipating bind profit pharynx, nourishing kidney yin.
Radix salviae miltiorrhizae, mildly bitter flavor, cold nature, bushing green blood, nourishing heart sedate, calming heart and tranquilizing mind, forgetful palpitation, palpitation with fear is insomnia, raw
New blood, removes hemostasis.
The radix paeoniae rubrathe, bitter, cold nature, return liver warp, clearing heat and cooling blood, blood stasis removing analgesic.
Safflower, taste is pungent is warm in nature, enter the heart, Liver Channel, invigorate blood circulation, stasis eliminatings pain relieving.
Ligusticum wallichii, taste is pungent is warm in nature, and enter liver, gallbladder channel, promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.
The banksia rose, taste is pungent, hardship are warm in nature, returns spleen, large intestine, tri-jiao channel, stagnant with leading in promoting qi circulation and relieving pain, reinforcing spleen to promote digestion, tune.
More than each traditional Chinese medicinal components cooperate, full side altogether into promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, warm kidney yang-tonifying, active dehumidifying it
Work(, treats both principal and secondary aspect of disease, strengthening vital QI to eliminate pathogenic factors, treats diabetes effect is significant and has no toxic side effect.
Compared with prior art, the present invention has following beneficial effect：The Chinese medicine for the treatment of diabetes of the present invention,
Each medicine complements each other, and with the effect of promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, warm kidney yang-tonifying, active dehumidifying, treatment diabetes take effect
Hurry up, effect is significant, Small side effects；Its preparation method is simply controllable, can be made into various formulations, facilitates patient to take.
Specific embodiment
With reference to specific embodiment, the present invention is expanded on further.These embodiments be merely to illustrate the present invention and without
In restriction the scope of the present invention.
Embodiment 1：
The present embodiment is related to a kind of Chinese medicine and preparation method for treating diabetes；
The Chinese medicine of the treatment diabetes includes each component of following parts by weight：3 parts of the Radix Astragali, 25 parts of RHIZOMA POLYGONATI PREPARATA, rhizoma atractylodis macrocephalae
15 parts, 20 parts of Chinese yam, 32 parts of coix seed, 20 parts of radix polygonati officinalis, 20 parts of cucurbit shell.
The Chinese medicinal preparation method is as follows：Each component is proportionally well mixed, plus 20 DEG C of 12 times of Chinese medicine gross weight
Water immersion 30min, be put into boiling machine, decoct 40min, filter off the dregs of a decoction, liquid press into 180ml/ bags and is pressed into Chinese herbal medicine bag, obtain final product,
Put 0-8 DEG C of refrigerator stored refrigerated.
Embodiment 2：
The present embodiment is related to a kind of Chinese medicine and preparation method for treating diabetes；
The Chinese medicine of the treatment diabetes includes each component of following parts by weight：3 parts of the Radix Astragali, 20 parts of RHIZOMA POLYGONATI PREPARATA, rhizoma atractylodis macrocephalae
20 parts, 25 parts of Chinese yam, 30 parts of coix seed, 25 parts of radix polygonati officinalis, 20 parts of cucurbit shell.
The Chinese medicinal preparation method is as follows：Each component is proportionally well mixed, plus 30 DEG C of 10 times of Chinese medicine gross weight
Water immersion 20min, be put into boiling machine, decoct 40min, filter off the dregs of a decoction, liquid press into 200ml/ bags and is pressed into Chinese herbal medicine bag, obtain final product,
Put 0-8 DEG C of refrigerator stored refrigerated.
Embodiment 3：
The present embodiment is related to a kind of Chinese medicine and preparation method for treating diabetes；
The Chinese medicine of the treatment diabetes includes each component of following parts by weight：5 parts of the Radix Astragali, 15 parts of RHIZOMA POLYGONATI PREPARATA, rhizoma atractylodis macrocephalae
20 parts, 25 parts of Chinese yam, 40 parts of coix seed, 25 parts of radix polygonati officinalis, 25 parts of cucurbit shell.
The Chinese medicinal preparation method is as follows：Each component is proportionally well mixed, plus 30 DEG C of 10 times of Chinese medicine gross weight
Water immersion 20min, be put into boiling machine, decoct 40min, filter off the dregs of a decoction, liquid press into 190ml/ bags and is pressed into Chinese herbal medicine bag, obtain final product,
Put 0-8 DEG C of refrigerator stored refrigerated.
Embodiment 4：
The present embodiment is related to a kind of Chinese medicine and preparation method for treating diabetes；
The Chinese medicine of the treatment diabetes includes each component of following parts by weight：4 parts of the Radix Astragali, 25 parts of RHIZOMA POLYGONATI PREPARATA, rhizoma atractylodis macrocephalae
15 parts, 25 parts of Chinese yam, 35 parts of coix seed, 25 parts of radix polygonati officinalis, 20 parts of cucurbit shell.
The Chinese medicinal preparation method is as follows：After each traditional Chinese medicinal components mixing, 10 times of Chinese medicine gross weight of water immersion is added
0.5, heating decocts 50min, filters to obtain decoction liquor, and the secondary decoction of water of 6 times of initial Chinese medicine gross weight is added in the dregs of a decoction, decocts
30min, filters to obtain decoction liquor, and decoction liquor merging twice is concentrated into relative density for 1.25（70℃）, add 80% ethanol tune
Section alcohol content reaches 50%, stirs evenly, and stands 12h, and filtration, filtrate recycling ethanol is concentrated into the thick paste without alcohol taste, drying under reduced pressure into
Dry extract, adds amylum pregelatinisatum and magnesium stearate, and granulation, compressing tablet are obtained tablet.Embodiment 5：
The present embodiment is related to a kind of Chinese medicine and preparation method for treating diabetes；
The Chinese medicine of the treatment diabetes includes each component of following parts by weight：3 parts of the Radix Astragali, 22 parts of RHIZOMA POLYGONATI PREPARATA, rhizoma atractylodis macrocephalae
20 parts, 21 parts of Chinese yam, 30 parts of coix seed, 22 parts of radix polygonati officinalis, 22 parts of cucurbit shell.
The Chinese medicine preparation process is as follows：After each traditional Chinese medicinal components mixing, 8 times of Chinese medicine gross weight of water immersion 1h is added,
Heating decocts 40min, filters to obtain decoction liquor, and the secondary decoction of water of 8 times of initial Chinese medicine gross weight is added in the dregs of a decoction, decocts
40min, filters to obtain decoction liquor, and decoction liquor merging twice is concentrated into relative density for 1.18（50℃）, add 95% ethanol tune
Section alcohol content reaches 50%, stirs evenly, and stands 16h, and filtration, filtrate recycling ethanol is concentrated into the thick paste without alcohol taste, drying under reduced pressure into
Dry extract, adds lactose and dextrin, wet granulation, obtains granule.
Clinical data：
Physical data：All of diabetes patient 36, the outpatient service being during our hospital's in May, -2016 in January, 2015 and
Inpatient, medicine group case man 20 of the present invention, female 16；- 68 years old 40 years old age, average age 51 years old；Course of disease 3-10,
Average course of disease 6 years, diabetes history -8 months 2 weeks, sufferer is without other serious diseases.Medicine group all cases of the present invention meet
The diabetes that the national diabetes academic conference of Chinese Medical Association first is formulated（Acral necrosis）Diagnostic criteria（Draft）.
Method of administration：Patient takes obtained decoction in the embodiment of the present invention 1, and 2 times a day, sooner or later respectively once, aftermeals
With two weeks is 1 course for the treatment of, observes 4 courses for the treatment of.Coordinate following treatment method while medication：1. insulin therapy, makes blood sugar
Control is between 7～9mmol/L；2. concurrent infection person, gives anti-inflammatory and symptomatic treatment；3. for the sufficient surface of a wound of trouble does accordingly
Process.
Curative effect determinate standard（Reference《The diagnosis and treatment of diabetes and related complication》）
Cure：Surface of a wound all healed, has formed crust or scar；
Take a turn for the better：Gangrenous merocrine secretion's thing is significantly reduced, and gangrene, slough major part come off or part granulation is newborn, and the surface of a wound shows
Write and reduce.
It is invalid：, without being obviously reduced, without significantly reducing, gangrene local is without significant changes or deterioration for secretion for the gangrenous surface of a wound.
Treatment results are counted：
As can be seen from the above table, the Chinese medicine for the treatment of diabetes of the present invention, therapeutic effect is good, and instant effect has no side effect.
Model case and curative effect：
Beam, Mt. Huang in Anhui people from city, female, 49 years old, diabetes 3 years, diabetes history 4 months, the right side was carried on the back fully visible 6 × 5cm and is burst
Face, substantially, after the treatment by Chinese herbs of 2 courses for the treatment of and local debridement dressing change, gangrenous merocrine secretion's thing is obvious for biped swelling
Reduce, the surface of a wound is reduced significantly；After the treatment by Chinese herbs of 4 courses for the treatment of and local debridement dressing change, wound healing.
Pacify certain, Mt. Huang in Anhui people from city, man, 58 years old, diabetes 5 years, diabetes history 6 months, double lower limb swelling, toe-end became
Visible 10 × 8cm ulcerations are carried on the back fully on shape, the right side, visible a little granulation growth, week skin whitening of bursting on ulceration, and the toe face of left foot the 2nd can
See 2 × 2cm ulcerations, attached yellow-white membranoid substance and slough on ulceration, biped swelling is obvious.Control through the Chinese medicine of 4 courses for the treatment of
After treatment and local debridement dressing change, gangrenous merocrine secretion's thing is significantly reduced, and the surface of a wound is reduced significantly.
The specific embodiment of the present invention is described above.It is to be appreciated that the invention is not limited in above-mentioned
Particular implementation, those skilled in the art can within the scope of the claims make various modifications or modification, this not shadow
Ring the flesh and blood of the present invention.
Claims (8)
1. a kind of Chinese medicine for treating diabetes, it is characterised in that：Described Chinese medicine includes each component of following parts by weight：It is yellow
10～20 parts of stilbene, 5～15 parts of corydalis tuber processed, 5～15 parts of motherwort, 5～15 parts of peach kernel, 10～20 parts of stir-baked RADIX PAEONIAE ALBA, radix scrophulariae 5～15
Part, 5～15 parts of radix salviae miltiorrhizae, 5～12 parts of the radix paeoniae rubrathe, 5～15 parts of safflower, 5～12 parts of Ligusticum wallichii, 4～10 parts of the banksia rose.
2. it is according to claim 1 treatment diabetes Chinese medicine, it is characterised in that：Described Chinese medicine includes following weight
The each component of number：15～20 parts of the Radix Astragali, 8～15 parts of corydalis tuber processed, 8～15 parts of motherwort, 8～15 parts of peach kernel, stir-baked RADIX PAEONIAE ALBA 10～
20 parts, 8～15 parts of radix scrophulariae, 8～15 parts of radix salviae miltiorrhizae, 8～12 parts of the radix paeoniae rubrathe, 8～15 parts of safflower, 5～12 parts of Ligusticum wallichii, the banksia rose 4～10
Part.
3. it is according to claim 2 treatment diabetes Chinese medicine, it is characterised in that：Described Chinese medicine includes following weight
The each component of number：15 parts of the Radix Astragali, 10 parts of corydalis tuber processed, 13 parts of motherwort, 8 parts of peach kernel, 12 parts of stir-baked RADIX PAEONIAE ALBA, 8 parts of radix scrophulariae, radix salviae miltiorrhizae
12 parts, 8 parts of the radix paeoniae rubrathe, 10 parts of safflower, 10 parts of Ligusticum wallichii, 8 parts of the banksia rose.
4. it is according to claim 2 treatment diabetes Chinese medicine, it is characterised in that：Described Chinese medicine includes following weight
The each component of number：15 parts of the Radix Astragali, 10 parts of corydalis tuber processed, 10 parts of motherwort, 10 parts of peach kernel, 12 parts of stir-baked RADIX PAEONIAE ALBA, 10 parts of radix scrophulariae, purple pellet
10 parts of ginseng, 8 parts of the radix paeoniae rubrathe, 10 parts of safflower, 8 parts of Ligusticum wallichii, 6 parts of the banksia rose.
5. it is a kind of as any one of claim 1-4 treat diabetes Chinese medicine preparation method, it is characterised in that：Institute
State preparation method as follows：Each component is proportionally well mixed, plus 20～30 DEG C of water soaks 20～30min, and it is put into and boils medicine
Machine, decocts 40min, filters off the dregs of a decoction, and liquid is pressed into Chinese herbal medicine bag by 180～200ml/ bags, obtains final product.
6. the preparation method of the Chinese medicine of diabetes is treated according to claim 5, it is characterised in that：It is described to add the total of water
Weight is 10～12 times of Chinese medicine gross weight.
7. it is a kind of as any one of claim 1-4 treat diabetes Chinese medicine preparation method, it is characterised in that：Institute
State preparation method as follows：After each traditional Chinese medicinal components mixing, the water for adding 8～10 times of Chinese medicine gross weight soaks 0.5～1h, and heating is decocted
40～50min, filters to obtain decoction liquor, adds initial Chinese medicine gross weight to add 6～8 times of the secondary decoction of water in the dregs of a decoction, decocts
30～40min, filters to obtain decoction liquor, and decoction liquor merging twice is concentrated into relative density for 1.18～1.25（50-70℃）, plus
The ethanol regulation alcohol content for entering 80～95% reaches 50%, stirs evenly, and stands more than 12h, and filtration, filtrate recycling ethanol is concentrated into nothing
The thick paste of alcohol taste, drying under reduced pressure adds pharmaceutically acceptable forming agent auxiliary material into dry extract, makes Chinese medicine preparation.
8. the preparation method of diabetes Chinese medicine is treated according to claim 7, it is characterised in that：The Chinese medicine preparation includes
Granule, capsule, tablet.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107854560A (en) * | 2017-12-02 | 2018-03-30 | 洪雅县瓦屋山药业有限公司 | A kind of medicine for treating diabetes and preparation method thereof |
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|---|---|---|---|---|
| CN102319327A (en) * | 2011-10-11 | 2012-01-18 | 张俊瑕 | Traditional Chinese medicine for internally and externally treating diabetic foot |
| CN103784821A (en) * | 2012-11-02 | 2014-05-14 | 厉岩 | Traditional Chinese medicinal composition for treating diabetic foot |
| CN104352619A (en) * | 2014-10-21 | 2015-02-18 | 韦丽梅 | Foot bath formula for treating diabetes |
| CN105106498A (en) * | 2015-10-07 | 2015-12-02 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine composition for treating diabetic foot |
-
2016
- 2016-11-29 CN CN201611071674.6A patent/CN106620001A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319327A (en) * | 2011-10-11 | 2012-01-18 | 张俊瑕 | Traditional Chinese medicine for internally and externally treating diabetic foot |
| CN103784821A (en) * | 2012-11-02 | 2014-05-14 | 厉岩 | Traditional Chinese medicinal composition for treating diabetic foot |
| CN104352619A (en) * | 2014-10-21 | 2015-02-18 | 韦丽梅 | Foot bath formula for treating diabetes |
| CN105106498A (en) * | 2015-10-07 | 2015-12-02 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine composition for treating diabetic foot |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107854560A (en) * | 2017-12-02 | 2018-03-30 | 洪雅县瓦屋山药业有限公司 | A kind of medicine for treating diabetes and preparation method thereof |
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Application publication date: 20170510 |