CN103784821A - Traditional Chinese medicinal composition for treating diabetic foot - Google Patents
Traditional Chinese medicinal composition for treating diabetic foot Download PDFInfo
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- CN103784821A CN103784821A CN201210431115.7A CN201210431115A CN103784821A CN 103784821 A CN103784821 A CN 103784821A CN 201210431115 A CN201210431115 A CN 201210431115A CN 103784821 A CN103784821 A CN 103784821A
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating diabetic foot, and belongs to the field of traditional Chinese medicinal compositions. The traditional Chinese medicinal composition is composed of Salvia miltiorrhiza, fried peach seed, Ligusticum wallichii, Radix Astragali, Radix Codonopsis, fried Rhizoma Atractylodis Macrocephalae, Spina Gleditsiae, Caulis Sargentodoxae, Radix Scrophulariae, unprepared rehmannia root, white peony root, leech, fried Atractylodes lancea, Radix Paeoniae Rubra, Glabrous Greenbrier Rhizome and licorice root according to a certain weight ratio. The traditional Chinese medicinal composition has the advantages of good curative effect, short treatment course, high cure rate and low cost, and is worthy to be popularized clinically.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of diabetic foot.
Background technology
Diabetic foot refers to the destruction that diabetics causes lower limb infection, ulcer and (or) deep tissue due to factors such as diabetic angiopathy and (or) neuropathy and infection.Diabetic foot often shows as xerosis cutis on foot, poor flexibility, and color of the leather is dimmed, numb limbs and tense tendons, perceptual difference, engender twinge, skelalgia after long-time walking, also pain while progressively developing into rest, arteriopalmus weakens or disappears, and serious caused skin ulceration, infection suppurates are even downright bad.Treatment diabetic foot, to put prevention first, is avoided foot damage as possible, and common general treatment means are: strictly control blood glucose, eliminate the risk factor that causes vascular lesion, and as hypertension, hyperlipidemia etc.Use antibiotic to treat for diabetic foot at present, but the antibiotic therapy cycle is long, toxic side effect more; Also have for this sick Chinese medicine, but Chinese medicine formula complexity and onset are slow.
Summary of the invention
The object of the invention is in order to solve above-mentioned technical deficiency, provide good effect, short treating period, cure rate high, a kind of Chinese medicine composition for the treatment of glycosuria foot that cost is low.
The present invention selects Radix Salviae Miltiorrhizae, Semen Persicae (parched), Rhizoma Chuanxiong, the Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Spina Gleditsiae, Caulis Sargentodoxae, Radix Scrophulariae, Radix Rehmanniae, the Radix Paeoniae Alba, Hirudo, Rhizoma Atractylodis (parched), Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae, Radix Glycyrrhizae to combine, make each efficacy of drugs produce synergism, there is effect of dredging the meridian, activating blood circulation to dissipate blood stasis, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, current QI and blood, promoting tissue regeneration by astringents, thereby can effectively treat diabetic foot.
Wherein each raw material effect in formula:
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae salvia Radix Salviae Miltiorrhizae.Bitter in the mouth, slightly warm in nature.Enter the heart, Liver Channel.There is blood circulation promoting and blood stasis dispelling, pain relieving eliminating carbuncle, effect of nourishing blood to tranquillize the mind.Be used for improving microcirculation, promote reparation and the regeneration of tissue, alleviate local congestion, improve blood circulation, shorten healing time.
Semen Persicae (parched): be the dry mature seed of rosaceous plant Fructus Persicae or Prunus davidiana.Bitter in the mouth, sweet, property is flat.GUIXIN, liver, large intestine channel.There is effect of blood circulation promoting and blood stasis dispelling, for vasodilator, suppress blood coagulation and haemolysis, improve blood flow retardance, blood obstacle.
Rhizoma Chuanxiong: be the rhizome of samphire Rhizoma Chuanxiong.Acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.There is blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, effect of wind-expelling pain-stopping.
The Radix Astragali: be the root of leguminous plant Radix Astagali or Radix Astragali.Sweet in the mouth, slightly warm in nature.Return lung, spleen, liver, kidney channel.There is holder skin ulcer granulation promoting, inducing diuresis to remove edema, effect of expelling pus and toxin by strengthening QI, the astragalus polysaccharides in the Radix Astragali can also be used for enhancing immunity.
Radix Codonopsis: be the root of Campanulaceae Radix Codonopsis, element flower Radix Codonopsis, radix codonpsis tangshen, pipe flower Radix Codonopsis, C. subglobosa, C. canescens.Sweet in the mouth, property is flat, micro-acid.Return spleen, lung meridian.Have effect of nourishing blood to promote the production of body fluid, form for suppressing thrombus in vivo, reduce hyperlipemia, expansion peripheral vessels reduces blood pressure.
Rhizoma Atractylodis Macrocephalae (parched): be the rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Have dampness diuretic, effect of strengthening superficial resistance to stop perspiration, for blood sugar lowering, extends clotting time, anticoagulant.
Spina Gleditsiae: be the Spina jujubae of leguminous plant Fructus Gleditsia.Acrid in the mouth, warm in nature.Return lung, Liver Channel.There is promoting blood circulation by removing wind, effect of detumescence and apocenosis.
Caulis Sargentodoxae: be the stem of plants of Lardizabalaceae Caulis Sargentodoxae.Bitter in the mouth, property is flat.Enter liver, large intestine channel.There is dispersing swelling and dissipating binds, effect of vital energy regualting and blood circulation-promoting.
Radix Scrophulariae: be the dry root of dicotyledon Scrophulariaceae Radix Scrophulariae.Sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.There is effect of clearing away heat and cooling blood, for expanding lower limb vascular.
Radix Rehmanniae: be the root of dicotyledon medicine scrophulariaceae rehmannia glutinosa plant or bosom celebrating Radix Rehmanniae.Sweet-bitter flavor, cool in nature.Enter the heart, liver, kidney channel.There is effect of clearing away heat and cooling blood, for promoting blood coagulation, reducing blood glucose.
The Radix Paeoniae Alba: be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Bitter in the mouth acid, cool in nature.Enter liver, spleen channel.There is the pain relieving of nourishing blood, clear and coherent blood vessels, effect of subduing inflammation.
Hirudo: be being dried all of Hirudinidae animal Hirudo, Hirudo or whitmania acranulata Whitman.Salty in the mouth, hardship, property is flat, nontoxic.Return Liver Channel.There is effect of blood stasis dispelling blood, for suppressing thrombosis.
Rhizoma Atractylodis (parched): be the dry rhizome of feverfew Atractylodes lancea (Thunb.) DC. or Atractylis chinensis, acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.There is the loose swollen effect of dispeling the wind.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Rubra or river Radix Paeoniae Rubra.Bitter in the mouth, cold nature.Return Liver Channel.There is effect of clots absorbing pain relieving, removing heat from blood detumescence, for suppressing thrombosis and platelet aggregation.
Rhizoma Smilacis Glabrae: be the dry rhizome of dicotyledon medicine liliaceous plant smilacis glabra.Slightly sweet flavor, property is flat.Return liver, stomach, spleen channel.There is effect of damp eliminating removing toxic substances.
Radix Glycyrrhizae: be the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.There is heat-clearing and toxic substances removing, alleviate effect of toxicity.
Medicine material consumption of the present invention is groped in a large number to sum up through inventor and is drawn, each raw material consumption is for all to have good curative effect in following weight parts scope: Radix Salviae Miltiorrhizae 15-25 part, Semen Persicae (parched) 7-17 part, Rhizoma Chuanxiong 7-17 part, Radix Astragali 40-60 part, Radix Codonopsis 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 15-25 part, Spina Gleditsiae 20-28 part, Caulis Sargentodoxae 20-28 part, Radix Scrophulariae 10-20 part, Radix Rehmanniae 15-25 part, Radix Paeoniae Alba 10-20 part, Hirudo 5-15 part, Rhizoma Atractylodis (parched) 10-20 part, Radix Paeoniae Rubra 10-20 part, Rhizoma Smilacis Glabrae 15-25 part, Radix Glycyrrhizae 5-13 part.
Its optimum weight proportioning component: 20 parts of Radix Salviae Miltiorrhizaes, 12 parts of Semen Persicae (parched)s, 12 parts of Rhizoma Chuanxiongs, 50 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae, 15 parts of Radix Scrophulariaes, 20 parts of Radix Rehmanniae, 15 parts of the Radix Paeoniae Albas, 10 parts of Hirudos, 15 parts of Rhizoma Atractylodis (parched), 15 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Smilacis Glabraes, 9 parts of Radix Glycyrrhizae.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into powder.Specifically these crude drug pulverize mix homogeneously can be made to powder, put into hot water or directly decocting become decoction foot bath.
Medicine of the present invention has effect of dredging the meridian, activating blood circulation to dissipate blood stasis, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, current QI and blood, promoting tissue regeneration by astringents, and good effect, cure rate are high, and cost is low.Through 100 routine system clinical observations, experimental result statistics, patients whose symptoms were less severe only use a course for the treatment of of the present invention, total effective rate 92%, symptom is used two courses for the treatment of, total effective rate 97% compared with severe one.
The specific embodiment
Embodiment mono-, 15 parts of Radix Salviae Miltiorrhizaes, 7 parts of Semen Persicae (parched)s, 7 parts of Rhizoma Chuanxiongs, 40 parts of the Radixs Astragali, 10 parts of Radix Codonopsis, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 20 parts of Spina Gleditsiaes, 20 parts of Caulis Sargentodoxae, 10 parts of Radix Scrophulariaes, 15 parts of Radix Rehmanniae, 10 parts of the Radix Paeoniae Albas, 5 parts of Hirudos, 10 parts of Rhizoma Atractylodis (parched), 10 parts of Radix Paeoniae Rubra, 15 parts of Rhizoma Smilacis Glabraes, 5 parts of Radix Glycyrrhizae.
Embodiment bis-, 20 parts of Radix Salviae Miltiorrhizaes, 12 parts of Semen Persicae (parched)s, 12 parts of Rhizoma Chuanxiongs, 50 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae, 15 parts of Radix Scrophulariaes, 20 parts of Radix Rehmanniae, 15 parts of the Radix Paeoniae Albas, 10 parts of Hirudos, 15 parts of Rhizoma Atractylodis (parched), 15 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Smilacis Glabraes, 9 parts of Radix Glycyrrhizae.
Embodiment tri-, 25 parts of Radix Salviae Miltiorrhizaes, 17 parts of Semen Persicae (parched)s, 17 parts of Rhizoma Chuanxiongs, 60 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 25 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 28 parts of Spina Gleditsiaes, 28 parts of Caulis Sargentodoxae, 20 parts of Radix Scrophulariaes, 25 parts of Radix Rehmanniae, 20 parts of the Radix Paeoniae Albas, 15 parts of Hirudos, 20 parts of Rhizoma Atractylodis (parched), 20 parts of Radix Paeoniae Rubra, 25 parts of Rhizoma Smilacis Glabraes, 13 parts of Radix Glycyrrhizae.
The clinical statistics data that patient uses medicine of the present invention below:
One, physical data
Accept out-patient's totally 100 examples for medical treatment, wherein male's 64 examples, women's 36 examples, M-F 1.8:1,58 years old mean age.
Two, diagnostic criteria
Tcm diagnosis standard is with reference to " guideline of clinical investigations of traditional Chinese medical science Drugs in Therapy diabetes ".Diabetic foot Syndrome Differentiation of Traditional Chinese Medicine:
Clinical manifestation: acromelic gangrene, black, wound surface exudate is less, and limbs are sent out cool to be afraid of cold, and pain numbness is insensitive, palor, thin white fur of tongue, tongue is dark red, a little less than deep-thready pulse.
Three, using method:
Patient with diabetic feet is put in tub or enamel basin by powder after cleaning by warm water, and foot bath 20～30 minutes when putting into hot water and being cooled to 37 ℃ ~ 39 ℃ can constantly be converted when water is cool and be added boiled water and increase to temperature requiredly, and bubble future trouble foot dries naturally, every day twice, at every turn potion.30 days course for the treatment of.
The scope of application: the present invention is mainly suitable for diabetic foot by the 1-3 level in grading Wagner staging and convalescent period that more than 3 grades actute infection has been controlled.
Taboo item: (1) after meal half an hour unsuitable foot bath, the foot bath time should not exceed half an hour.
(2) foot has infection or bleeding, forbid foot bath.
Four, efficacy assessment standard
Criterion of therapeutical effect is with reference to " diagnosis and treatment of diabetic foot and related complication ".
Cure: gangrenous wound surface heals completely, has formed crust or cicatrix.
Take a turn for the better: gangrenous merocrine secretion thing obviously reduces, gangrene, slough major part come off or part granulation new life, and wound surface significantly dwindles.
Invalid: gangrenous wound surface is without obviously dwindling, and secretions is without obvious minimizing, and gangrene is local without significant change or deterioration.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, patient Liu, female, 56 years old, the glucose in urine positive before 2 years, oral antidiabetic drug, before year, pedal skin is pale when lower limb lifting, is aubergine when lower limb are sagging, and foot is sent out cool, and pulsation of foot dorsal artery weakens, and outpatient service is diagnosed as diabetic foot.Through patient, with being intended to continue to coordinate in the situation of oral medicine a course for the treatment of of external foot bath, clinical symptoms disappears completely, does not recur again.
Case two, patient Song, man, 62 years old, suffers from diabetes 7 years.Recently, often there is numb twinge in double-legged toe, meet that cold pain increases the weight of, blackening in toenail, xerosis cutis, poor flexibility on foot, and color of the leather is dimmed, numb limbs and tense tendons, perceptual difference, skelalgia symptom after long-time walking.Continuing to coordinate oral medicine in the situation that two courses for the treatment of of external foot bath, toe erythrosis profit, clinical symptoms disappears completely, does not recur again.
Case three, patient Zhu, man, 68 years old, suffer from diabetes 10 years, medication treatment 7 years, feels coolness of extremities often, numbness is stepped on Cotton Gossypii sense, lower limbs edema, pruritus, twinge on foot.Continuing to coordinate oral medicine in the situation that a course for the treatment of of external foot bath, symptom is obviously improved, and continues a course for the treatment of of external, and clinical symptoms disappears completely, does not recur again.
Claims (2)
1. a Chinese medicine composition for the treatment of diabetic foot, is characterized in that, this Chinese medicine composition is the ingredients by following weight portion:
Radix Salviae Miltiorrhizae 15-25 part, Semen Persicae (parched) 7-17 part, Rhizoma Chuanxiong 7-17 part, Radix Astragali 40-60 part, Radix Codonopsis 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 15-25 part, Spina Gleditsiae 20-28 part, Caulis Sargentodoxae 20-28 part, Radix Scrophulariae 10-20 part, Radix Rehmanniae 15-25 part, Radix Paeoniae Alba 10-20 part, Hirudo 5-15 part, Rhizoma Atractylodis (parched) 10-20 part, Radix Paeoniae Rubra 10-20 part, Rhizoma Smilacis Glabrae 15-25 part, Radix Glycyrrhizae 5-13 part.
2. according to the Chinese medicine composition of the treatment diabetic foot described in claims 1, it is characterized in that, this Chinese medicine composition is the ingredients by following weight portion:
20 parts of Radix Salviae Miltiorrhizaes, 12 parts of Semen Persicae (parched)s, 12 parts of Rhizoma Chuanxiongs, 50 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae, 15 parts of Radix Scrophulariaes, 20 parts of Radix Rehmanniae, 15 parts of the Radix Paeoniae Albas, 10 parts of Hirudos, 15 parts of Rhizoma Atractylodis (parched), 15 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Smilacis Glabraes, 9 parts of Radix Glycyrrhizae.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620001A (en) * | 2016-11-29 | 2017-05-10 | 汪承武 | Traditional Chinese medicine for treating diabetic foots and preparation method thereof |
| CN107854560A (en) * | 2017-12-02 | 2018-03-30 | 洪雅县瓦屋山药业有限公司 | A kind of medicine for treating diabetes and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101167875A (en) * | 2007-10-25 | 2008-04-30 | 浙江省中药研究所有限公司 | Traditional Chinese medicinal preparation for treating diabetes and its preparing process |
| CN101229268A (en) * | 2007-07-27 | 2008-07-30 | 黄素文 | Retinervus-smoothing regeneration ointment |
| CN101648005A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
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2012
- 2012-11-02 CN CN201210431115.7A patent/CN103784821B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229268A (en) * | 2007-07-27 | 2008-07-30 | 黄素文 | Retinervus-smoothing regeneration ointment |
| CN101167875A (en) * | 2007-10-25 | 2008-04-30 | 浙江省中药研究所有限公司 | Traditional Chinese medicinal preparation for treating diabetes and its preparing process |
| CN101648005A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620001A (en) * | 2016-11-29 | 2017-05-10 | 汪承武 | Traditional Chinese medicine for treating diabetic foots and preparation method thereof |
| CN107854560A (en) * | 2017-12-02 | 2018-03-30 | 洪雅县瓦屋山药业有限公司 | A kind of medicine for treating diabetes and preparation method thereof |
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