CN107854560A - A kind of medicine for treating diabetes and preparation method thereof - Google Patents
A kind of medicine for treating diabetes and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to the field of Chinese medicines, more particularly to a kind of medicine for treating diabetic complication and preparation method thereof.Its technical scheme is：A kind of medicine for treating diabetes, including following component, wherein the number of each composition is by weight：1~2 part of the refined company of 20~40 parts of the Radix Astragali, wine, 8~15 parts of corydalis tuber processed, 4~12 parts of motherwort, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, 3~8 parts of the radix paeoniae rubrathe, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, 2~8 parts of the banksia rose.A kind of preparation method for the medicine for treating diabetes, comprises the following steps：1) medicinal material of each part by weight is weighed；2) filter residue is decocted.The invention provides a kind of medicine and preparation method that can effectively treat diabetes, solve the problems, such as that existing medicine can only pain of alleviation.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of medicine for treating diabetes and preparation method thereof.
Background technology
Diabetes be due to internal hypoinsulinism or effect defect caused by one kind with sugar, fat, protein etc.
Metabolic disorder is the common endocrine metabolism disease of principal character.In recent years, with the improvement of people ' s living standards, life side
The factors such as the change of formula, the incidence of disease rapid development of global diabetes, diabetes have become after tumour, cardiovascular pathological changes
The third-largest serious threat human health and the common disease of life afterwards.Diabetes can not necessarily cause seriously to patient in itself
Harm, but long-term blood glucose increases, and big blood vessel, capilary be damaged and jeopardize the heart, brain, kidney, peripheral nerve, eyes, foot etc., understand with trouble
Person's course advancement causes a series of diabetic complication.Counted according to the World Health Organization, diabetic complication is up to more than 100
Kind, it is to be currently known a kind of most disease of complication.The complications of diabetes be influence diabetic quality of life and
Cause diabetic's death chief reason.
The major complications of diabetes have diabetes, diabetic eye diseases, diabetic nephropathy, diabetic neuropathy, sugar
Urinate a variety of diseases such as disease cardiovascular pathological changes.Wherein, diabetes refer to diabetic under hyperglycaemia environment by artery of lower extremity
Parteriole occlusion or the factor collective effect such as skin Microangiopathy and bacterium infection, DPN caused by hardening,
Cause foot numbness, pain, infection, the ulcer even lesion such as gangrene.Diabetes are a kind of serious complication of diabetes, are
Diabetic is disabled, and severe one can cause amputation even threat to life.The lighter only has foot's hypodynia, skin surface ulcer；Moderate
Person deeper penetrating ulcer can occurs and merge soft tissue inflammation；Severe patient merges Soft Tissue Abscess: An Experimental, bone tissue simultaneously in ulcer
Lesion, toe, heel or preceding instep circumscribed gangrene, full pin gangrene can notably occur.
Because the diabetes course of disease is grown, clinical manifestation is different, along with patient is to the shortage of Diabetes Mellitus Knowledge, self-protection
Consciousness is not strong, and patient does not see a doctor in time, and clinician also lacks deep understanding and attention to this, in addition, being directed to the disease
The country is also without specific treatment method, and simply the of short duration analgesic relief of symptoms of general Western medicine, though effective in cure must not eradicate, causes the disease
Treatment be still a great problem at present.
The content of the invention
Instant invention overcomes the deficiencies in the prior art, there is provided a kind of medicine and preparation side that can effectively treat diabetes
Method, solve the problems, such as that existing medicine can only pain of alleviation.
To solve above-mentioned technical problem, the present invention uses following technical scheme：
A kind of medicine for treating diabetes, including following component, wherein the number of each composition is by weight：The Radix Astragali 20~
40 parts, 1~2 part of the refined company of wine, 8~15 parts of corydalis tuber processed, 4~12 parts of motherwort, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, the radix paeoniae rubrathe
3~8 parts, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, 2~8 parts of the banksia rose.
As the preferred scheme of the present invention, a kind of medicine for treating diabetes includes following component, wherein each composition
Number is by weight：1 part of the refined company of 33 parts of the Radix Astragali, wine, 12 parts of corydalis tuber processed, 8 parts of motherwort, 9 parts of radix scrophulariae, 9 parts of radix salviae miltiorrhizae, the radix paeoniae rubrathe 5
Part, 7 parts of safflower, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose.
A kind of preparation method for the medicine for treating diabetes, comprises the following steps：
1) medicinal material of each part by weight is weighed：Weigh 1~2 part of the refined company of 20~40 parts of the Radix Astragali, wine, 8~15 parts of corydalis tuber processed,
4~12 parts of motherwort, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, 3~8 parts of the radix paeoniae rubrathe, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, wood
It is fragrant 2~8 parts；
2) filter residue is decocted：Each composition is well mixed, adds 30~40 DEG C of water to soak 10~20min, is put into boiling machine, decoct
Boil, filter off the dregs of a decoction, produce.
As the preferred scheme of the present invention, the gross weight for adding water is 13~15 times of Chinese medicine gross weight.
As the preferred scheme of the present invention, in step 2), decoction process is：After each traditional Chinese medicinal components are mixed, in addition
The water immersion 15min that 8~10 times of medicine gross weight, heating decoct 45~55min, filter to obtain decoction liquor；Added into the dregs of a decoction initial
Chinese medicine gross weight adds 6~8 times of the secondary decoction of water, decocts 30~40min, filters to obtain decoction liquor；Decoction liquor it will merge twice
It is 1.18~1.25 (50~70 DEG C) to be concentrated into relative density, and the ethanol regulation alcohol content for adding 85~95% reaches 50%, stirs
It is even, more than 12h is stood, filtration, filtrate recycling ethanol, the thick paste of no alcohol taste is concentrated into, is dried under reduced pressure into dry extract, add pharmacy
Acceptable forming agent auxiliary material, is made Chinese medicine preparation.
The Radix Astragali, sweet, slight bitter, return lung, spleen, kidney channel have a tonifying Qi and lifting yang, invigorating qi for consolidating superficies, promoting blood circulation and removing obstruction in channels, tonifying spleen moistening lung,
Promote the production of body fluid to quench thirst, many effects such as promoting pus discharge and tissue regeneration and inducing diuresis for removing edema, the Radix Astragali mainly containing glycoside, polysaccharide, amino acid, trace element and
Flavones etc., organism metabolism, antifatigue, enhancing body's immunity, cardiac stimulant, anti-arrhythmia, anti anoxia, protection heart and brain can be promoted
A variety of effects such as blood vessel.
Prepared RHIZOMA COPTIDIS with vino is the Preparata of the coptis.With purging intense heat and detonicating, eliminating dampness, anti-inflammatory, sterilization, the effect of stomach invigorating.It is clinical
It is vexed to cure mainly excess heat, feeling of fullness, quenches one's thirst, spits blood, bleeding from five sense organs or subcutaneous tissue, hot eyes aphtha, sore scabies, bacillary dysentery, enteritis, the infection of the upper respiratory tract.
Corydalis tuber, warm-natured, acrid flavour is bitter, enters the heart, spleen, liver, lung, promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, especially to relieve pain the effect of and it is famous
In generation.It can also be used for each portion's qi stagnation blood stasis of whole body pain, injury from falling down.Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》Middle conclusion corydalis tuber has " living
Four large effects of blood, sharp gas, analgesic, diuresis ", and praise highly corydalis tuber " can the stagnation of the circulation of vital energy in promoting circulation of blood, stasis in gas, therefore specially control all over the body up and down
All pains ".The traditional Chinese medical science thinks, corydalis tuber is pungent to be dissipated, hardship is let out, Wen Tong, is both entered blood system, is entered qi leel again, gas that can be in promoting circulation of blood, in and can promoting the circulation of qi
Blood, the smooth blood of gas, no pain by smooth breath.
Motherwort, acrid flavour, hardship, cold nature, enter the heart, liver, bladder warp, there is the effect of stasis of blood, inducing diuresis to remove edema are adjusted in promoting blood circulation, this
Outside, also have the function that to resisting myocardial ischemia, reducing blood viscosity, resisting blood coagulation and protection kidney.
Radix scrophulariae is sweet, bitter, salty；Cold nature.Return lung, stomach, kidney channel.Radix scrophulariae is (left containing alkaloid, carbohydrate, sterol, amino acid
Revolve asparagine etc.), aliphatic acid (mainly oleic acid, leukotrienes, stearic acid), volatile oil, carrotene and retinoid material；
The effect of with clearing heat and cooling blood, purging intense heat and detonicating, dissipating bind relieving sore-throat, nourishing kidney yin.
Radix salviae miltiorrhizae, mildly bitter flavor, cold nature, bushing green blood, nourishing heart sedate, calming heart and tranquilizing mind, forgetful palpitation, palpitation with fear are insomnia, raw
New blood, removes hemostasis.
The radix paeoniae rubrathe, bitter, cold nature, return liver warp, clearing heat and cooling blood, blood stasis removing analgesic.
Safflower, acrid flavour is warm-natured, enters the heart, Liver Channel, invigorate blood circulation, stasis eliminatings analgesic.
Ligusticum wallichii, acrid flavour is warm-natured, and enter liver, gallbladder channel, promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.
The banksia rose, acrid flavour, hardship are warm-natured, returns spleen, large intestine, tri-jiao channel, stagnant with being led in promoting qi circulation and relieving pain, reinforcing spleen to promote digestion, tune.
More than each traditional Chinese medicinal components cooperate, full side is altogether into promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, warm kidney yang-tonifying, active dehumidifying
Work(, treat both principal and secondary aspect of disease, strengthening vital QI to eliminate pathogenic factors, treat diabetes significant effect and have no toxic side effect.
Compared with prior art, the beneficial effects of the invention are as follows：
1st, medicine of the invention, each medicine complement each other, and have promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, warm kidney yang-tonifying, active dehumidifying
Effect, treatment diabetes are quick, significant effect, Small side effects.The present invention can effectively treat diabetes, solution it is existing
The problem of medicine can only be in pain of alleviation, hope is brought for the radical cure of diabetes.
2nd, when each composition part by weight according to：1 part of the refined company of 33 parts of the Radix Astragali, wine, it is 12 parts of corydalis tuber processed, 8 parts of motherwort, profound
9 parts of ginseng, 9 parts of radix salviae miltiorrhizae, 5 parts of the radix paeoniae rubrathe, 7 parts of safflower, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose, the treatment requirement of the Chinese medicine can improve optimal
Play, can effectively treat diabetes, and drug side-effect can be reduced.
3rd, by the way that each medicinal material is weighed and decocted in proportion, the drug effect of each composition can be made to cooperate, be finally made
Available for the medicine for the treatment of diabetes, and effectively reduce the generation of side effect.
4th, the weight ratio for adding water is 13~15 times, it is ensured that the active ingredient of each medicinal material can be carried in decoction process
Take, beneficial to reservation drug effect.
5th, by decocting twice, can more fully boilery medicinal material active ingredient, and reduce side effect, be advantageous to medicine
The generation of thing, drug quality is improved, increases the therapeutic effect of medicine, and medicinal material can be saved.
Embodiment
The present invention is described in detail below.
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that specific embodiment described herein is not used to limit only to explain the present invention
The fixed present invention.
Embodiment one
A kind of medicine for treating diabetes, including following component, wherein the number of each composition is by weight：The Radix Astragali 20~
40 parts, 1~2 part of the refined company of wine, 8~15 parts of corydalis tuber processed, 4~12 parts of motherwort, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, the radix paeoniae rubrathe
3~8 parts, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, 2~8 parts of the banksia rose.
The medicine of the present invention, each medicine complement each other, and have promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, warm kidney yang-tonifying, the work(of active dehumidifying
Effect, treatment diabetes are quick, significant effect, Small side effects.The present invention can effectively treat diabetes, the existing medicine of solution
The problem of thing can only be in pain of alleviation, hope is brought for the radical cure of diabetes.
Embodiment two
On the basis of embodiment one, a kind of medicine for treating diabetes, including following component, wherein part of each composition
Number is by weight：1 part of the refined company of 33 parts of the Radix Astragali, wine, 12 parts of corydalis tuber processed, 8 parts of motherwort, 9 parts of radix scrophulariae, 9 parts of radix salviae miltiorrhizae, the radix paeoniae rubrathe 5
Part, 7 parts of safflower, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose.
When each composition part by weight according to：1 part of the refined company of 33 parts of the Radix Astragali, wine, 12 parts of corydalis tuber processed, 8 parts of motherwort, radix scrophulariae 9
Part, 9 parts of radix salviae miltiorrhizae, 5 parts of the radix paeoniae rubrathe, 7 parts of safflower, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose, the treatment requirement of the Chinese medicine can improve optimal hair
Wave, can effectively treat diabetes, and drug side-effect can be reduced.
Embodiment three
A kind of preparation method for the medicine for treating diabetes, comprises the following steps：
1) medicinal material of each part by weight is weighed：Weigh 1~2 part of the refined company of 20~40 parts of the Radix Astragali, wine, 8~15 parts of corydalis tuber processed,
4~12 parts of motherwort, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, 3~8 parts of the radix paeoniae rubrathe, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, wood
It is fragrant 2~8 parts；
2) filter residue is decocted：Each composition is well mixed, adds 30~40 DEG C of water to soak 10~20min, is put into boiling machine, decoct
Boil, filter off the dregs of a decoction, produce.
By the way that each medicinal material is weighed and decocted in proportion, the drug effect of each composition can be made to cooperate, final be made can
For treating the medicine of diabetes, and effectively reduce the generation of side effect.
Example IV
On the basis of above-mentioned any one embodiment, the gross weight for adding water is 13~15 times of Chinese medicine gross weight.
The weight ratio for adding water is 13~15 times, it is ensured that the active ingredient of each medicinal material can be extracted in decoction process,
Beneficial to reservation drug effect.
Embodiment five
On the basis of above-mentioned any one embodiment, in step 2), decoction process is：Each traditional Chinese medicinal components are mixed
Afterwards, the water immersion 15min of 8~10 times of Chinese medicine gross weight is added, heating decocts 45~55min, filters to obtain decoction liquor；Into the dregs of a decoction
The secondary decoction of water that initial Chinese medicine gross weight adds 6~8 times is added, 30~40min is decocted, filters to obtain decoction liquor；It will decoct twice
It is 1.18~1.25 (50~70 DEG C) that boil liquid merging, which is concentrated into relative density, and the ethanol regulation alcohol content of addition 85~95% reaches
To 50%, stir evenly, stand more than 12h, filtration, filtrate recycling ethanol, be concentrated into the thick paste of no alcohol taste, be dried under reduced pressure into dry leaching
Cream, pharmaceutically acceptable forming agent auxiliary material is added, Chinese medicine preparation is made.
By decocting twice, can more fully boilery medicinal material active ingredient, and reduce side effect, be advantageous to medicine
Generation, improve drug quality, increase the therapeutic effect of medicine, and medicinal material can be saved.
Claims (5)
1. a kind of medicine for treating diabetes, it is characterised in that including following component, wherein the number of each composition is by weight
Meter：1~2 part of the refined company of 20~40 parts of the Radix Astragali, wine, 8~15 parts of corydalis tuber processed, 4~12 parts of motherwort, 6~12 parts of radix scrophulariae, radix salviae miltiorrhizae 5
~12 parts, 3~8 parts of the radix paeoniae rubrathe, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, 2~8 parts of the banksia rose.
A kind of 2. medicine for treating diabetes according to claim 1, it is characterised in that including following component, wherein
The number of each composition is by weight：1 part of the refined company of 33 parts of the Radix Astragali, wine, 12 parts of corydalis tuber processed, 8 parts of motherwort, 9 parts of radix scrophulariae, radix salviae miltiorrhizae 9
Part, 5 parts of the radix paeoniae rubrathe, 7 parts of safflower, 8 parts of Ligusticum wallichii, 5 parts of the banksia rose.
3. a kind of preparation method for the medicine for treating diabetes, it is characterised in that comprise the following steps：
1) medicinal material of each part by weight is weighed：Weigh 1~2 part of the refined company of 20~40 parts of the Radix Astragali, wine, 8~15 parts of corydalis tuber processed, motherwort
4~12 parts, 6~12 parts of radix scrophulariae, 5~12 parts of radix salviae miltiorrhizae, 3~8 parts of the radix paeoniae rubrathe, 3~10 parts of safflower, 6~10 parts of Ligusticum wallichii, the banksia rose 2~8
Part；
2) filter residue is decocted：Each composition is well mixed, adds 30~40 DEG C of water to soak 10~20min, is put into boiling machine, decoct,
The dregs of a decoction are filtered off, are produced.
4. the preparation method of a kind of medicine for treating diabetes according to claim 3, it is characterised in that add water
Gross weight is 13~15 times of Chinese medicine gross weight.
5. the preparation method of a kind of medicine for treating diabetes according to claim 3, it is characterised in that in step 2)
In, decoction process is：After each traditional Chinese medicinal components are mixed, the water immersion 15min of 8~10 times of Chinese medicine gross weight is added, heating decocts
45~55min, filter to obtain decoction liquor；The secondary decoction of water that initial Chinese medicine gross weight adds 6~8 times is added into the dregs of a decoction, is decocted
30~40min, filter to obtain decoction liquor；It is 1.18~1.25 (50~70 DEG C) to incite somebody to action decoction liquor merging twice and be concentrated into relative density,
The ethanol regulation alcohol content for adding 85~95% reaches 50%, stirs evenly, and stands more than 12h, filtration, filtrate recycling ethanol, concentration
To the thick paste without alcohol taste, dry extract is dried under reduced pressure into, pharmaceutically acceptable forming agent auxiliary material is added, Chinese medicine preparation is made.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784821A (en) * | 2012-11-02 | 2014-05-14 | 厉岩 | Traditional Chinese medicinal composition for treating diabetic foot |
| CN106620001A (en) * | 2016-11-29 | 2017-05-10 | 汪承武 | Traditional Chinese medicine for treating diabetic foots and preparation method thereof |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784821A (en) * | 2012-11-02 | 2014-05-14 | 厉岩 | Traditional Chinese medicinal composition for treating diabetic foot |
| CN106620001A (en) * | 2016-11-29 | 2017-05-10 | 汪承武 | Traditional Chinese medicine for treating diabetic foots and preparation method thereof |
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