CN110227142A - A kind of liquid medicine and preparation method thereof - Google Patents

A kind of liquid medicine and preparation method thereof Download PDF

Info

Publication number
CN110227142A
CN110227142A CN201910697546.XA CN201910697546A CN110227142A CN 110227142 A CN110227142 A CN 110227142A CN 201910697546 A CN201910697546 A CN 201910697546A CN 110227142 A CN110227142 A CN 110227142A
Authority
CN
China
Prior art keywords
parts
grams
medicine
radix
liquid medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910697546.XA
Other languages
Chinese (zh)
Inventor
易森林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Changsha Wangcheng Mu Medicinal Liquor Co Ltd
Original Assignee
Changsha Wangcheng Mu Medicinal Liquor Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Changsha Wangcheng Mu Medicinal Liquor Co Ltd filed Critical Changsha Wangcheng Mu Medicinal Liquor Co Ltd
Publication of CN110227142A publication Critical patent/CN110227142A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8988—Gastrodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

This application discloses a kind of liquid medicine and preparation method thereof, cereal crops and Chinese medicinal material are boiled, medicine bubble, medicine steam, medicine makes and distillation process by medicine, the liquid medicine for assisting in the treatment of rheumatism is prepared.On the one hand, the solvent properties superpower using ethyl alcohol, the effective component in Chinese medicine is sufficiently leached out, and pharmacological property is stable, safe and effective；On the other hand, using the efficacy-enhancing ingredient function of ethyl alcohol, drug effect is made to be not fully exerted, alleviates the slow problem of herbal nature, improves the practicability of Chinese medicine.In addition, the preparation of the application liquid medicine is easy, and simplicity is taken, convenient for being widely used to promote.

Description

A kind of liquid medicine and preparation method thereof
Technical field
This application involves Chinese medicinal liquor technical fields more particularly to a kind of liquid medicine and preparation method thereof.
Background technique
Rheumatism is to involve the portions such as bone, joint and its surrounding tissue such as muscle, tendon, synovial bursa, fascia, ligament, nerve Position, using pain as the general name of a major class disease of main clinical manifestation.Because it is related with autoimmunity, the touching difficulty of numerous diseases More, some patients need lifelong medication treatment.It there is no the drug for eradicating such disease at present, western medical treatment is mainly that non-steroid is anti-inflammatory Medicine, immunosuppressor and hormone, the side effect of long-term administration are not answered ignored as its therapeutic effect.Traditional Chinese medicine is in wind There are the advantages such as small, the emphasis simultaneous treatment of principal and subordinate symptoms of toxic side effect, but Chinese medicine medicine soup decoction process is complicated, works slow in terms of the treatment of diseases caused by dampness Slowly, the course for the treatment of is long, and unobvious to some patientss curative effect.
It is slow that pharmacological property is directly taken in view of Chinese medicine, using the brewed Chinese medicinal material of white wine, in the superpower osmosis of ethyl alcohol Under, the effective component in Chinese medicinal material dissolves in wine liquid, will be integrated as the wine of beverage with the medicine " molten " to promote health and cure diseases, makes Medicine gives full play to its effect, improves curative effect, improves the practicability of Chinese medicine.Existing liquid medicine is of all shapes and colors, and health-care efficacy is multifarious, And for the liquid medicine of the diseases such as person in middle and old age's property waist-leg pain, swivel of hand muscular atrophy, arthritis, rheumatism and rheumatoid be difficult to play compared with Good adjuvant treatment effect.It would therefore be highly desirable to which one kind can effectively assist in the treatment of arthritis, person in middle and old age's property waist-leg pain, rheumatism, class wind Wet, the amyotrophic liquid medicine of swivel of hand.
Summary of the invention
This application provides a kind of liquid medicine and preparation method thereof, are controlled with solving the auxiliary of the existing liquid medicine for rheumatism The bad problem of therapeutic effect.
This application provides a kind of liquid medicine, for assisting in the treatment of person in middle and old age's property waist-leg pain, swivel of hand muscular atrophy, joint Diseases, the liquid medicine such as scorching, rheumatism and rheumatoid include the Chinese medicine material of following parts by weight: 20-25 grams of 20-25 grams of radix bupleuri plus skin, 35-45 grams of Radix Astragali, 15-25 grams of ginger, 20-25 grams of pollen, Yun Ling 15-25 gram, 25-35 grams of Chinese yam, 20-25 grams of gallbladder grass, Rhizoma Chuanxiong 15-25 grams, radix saposhnikoviae 15-25 grams, Gui Zi 5-25 gram, 25-35 grams of Radix Notoginseng, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of asarum, Cortex Magnoliae Officinalis 15-25 Gram, it is 25-35 grams of Rhizoma Gastrodiae, 25-35 grams of Radix Codonopsis, 25-35 grams of Rhizoma Atractylodis Macrocephalae, 5-15 grams of red ginseng, 10-20 grams of radix achyranthis bidentatae, 10-20 grams of Radix Paeoniae Alba, red 45-55 grams of jujube closes 10-20 grams of blood, 15-25 grams of the tuber of multiflower knotweed, 25-35 grams of fructus lycii, 15-25 grams of gentianae macrophyllae, 25-35 grams of rhizoma atractylodis, Cortex Eucommiae 15- 25 grams, 15-25 grams of six sweat, 15-25 grams of Rhizoma Et Radix Notopterygii, 15-25 grams of safflower, 25-35 grams of dried orange peel, 15-25 grams, 25-35 grams of Radix Rehmanniae of parasitism And 20-25 grams of radix rehmanniae preparata.
Optionally, the Chinese medicine material including following parts by weight: 25 parts of radix bupleuri plus 25 parts of skin, 40 parts of Radix Astragali, ginger 20 Part, 25 parts of pollen, 20 parts of Yun Ling, 30 parts of Chinese yam, gallbladder grass 25 parts, 20 parts of Rhizoma Chuanxiong, radix saposhnikoviae 20 parts, 15 parts of Gui Zi, 30 parts of Radix Notoginseng, when Return 30 parts, 10 parts of asarum, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Gastrodiae, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of red ginseng, 15 parts of radix achyranthis bidentatae, Radix Paeoniae Alba 15 Part, closes 15 parts of blood, 20 parts of the tuber of multiflower knotweed, 30 parts of fructus lycii, 20 parts of gentianae macrophyllae, 30 parts of rhizoma atractylodis, 20 parts of Cortex Eucommiae, 20 parts of six sweat, Qiang at 50 parts of jujube 20 parts living, 20 parts of safflower, 30 parts of dried orange peel, 20 parts parasitic, 30 parts of Radix Rehmanniae and 25 parts of radix rehmanniae preparata.
The application also provides a kind of liquid medicine preparation method, is used to prepare above-mentioned liquid medicine, liquid medicine preparation method include stock, Medicine boils, medicine steeps, medicine steams, medicine is made and distillation process, wherein
Procedure for preparation specifically includes: prepare required Chinese medicine material, it is spare after ground, mixing；It selects good available It is spare after being cleaned, being dried in the cereal crops of wine brewing；
Medicine boiling procedure specifically includes: suitable quantity of water being added in Chinese medicine material and is decocted, and by filtered Chinese medicine medicine soup It is cooling, spare；
Medicine bubble process specifically includes: clean cereal crops being poured into Chinese medicine medicine soup and are impregnated, after impregnating 25-45h, are carried out Filtering, cereal crops and filtered Chinese medicine medicine soup after being impregnated, wherein the cereal crops after immersion are used for subsequent medicine Technique is steamed, filtered Chinese medicine medicine soup storage makes technique to be ready for use on subsequent medicine；
Medicine steaming process specifically includes: the cereal crops after immersion being put into food steamer and carry out boiling；
Medicine is made process and is specifically included: being put into distiller's yeast after the cereal crops cooling after boiling, is put into fermentation after mixing evenly It is sealed fermentation in cylinder, after fermentation 4-6 days, filtered Chinese medicine medicine soup obtained in medicine bubble technique is poured into close in jar fermenter Envelope is impregnated 25-30 days, and cereal crops are pulled out out of jar fermenter, obtains liquid medicine stoste；
Distillation process specifically includes: liquid medicine stoste being put into food steamer and is boiled with soft fire 6-8h in, distillation obtains liquid medicine.
Optionally, the liquid medicine preparation method further includes sealing process, and the sealing process specifically includes: distillation is obtained Liquid medicine is put into wine vat sealing, is placed in shady place 25-40 days.
Optionally, the cereal crops include one of paddy, sorghum, millet, corn, sweet potato or a variety of.
Optionally, water used in medicine boiling procedure is Ebony Hill mountain spring water.
Optionally, medicine boils in technique, decocting time 4-6h.
Optionally, medicine steams in technique, digestion time 4-6h.
Liquid medicine provided by the present application and preparation method thereof, cereal crops and Chinese medicinal material are boiled by medicine, medicine bubble, medicine steam, Medicine makes and distillation process, and the liquid medicine for assisting in the treatment of rheumatism is prepared.On the one hand, special using the superpower solvent of ethyl alcohol Property, the effective component in Chinese medicine is sufficiently leached out, pharmacological property is stable, safe and effective；On the other hand, the medicine of ethyl alcohol is utilized Draw function, drug effect is made to be not fully exerted, alleviates the slow problem of herbal nature, improve the practicability of Chinese medicine.In addition, this Apply for that the preparation of liquid medicine is easy, and take simplicity, convenient for being widely used to promote.
Specific embodiment
The application provides a kind of liquid medicine, for assist in the treatment of person in middle and old age's property waist-leg pain, swivel of hand muscular atrophy, arthritis, The diseases such as rheumatism and rheumatoid.The liquid medicine of the application includes the Chinese medicine material of following parts by weight: 20-25 grams of radix bupleuri plus skin 20- 25 grams, 35-45 grams of Radix Astragali, 15-25 grams of ginger, 20-25 grams of pollen, Yun Ling 15-25 gram, 25-35 grams of Chinese yam, 20-25 grams of gallbladder grass, 15-25 grams of Rhizoma Chuanxiong, radix saposhnikoviae 15-25 grams, Gui Zi 5-25 gram, 25-35 grams of Radix Notoginseng, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of asarum, Cortex Magnoliae Officinalis 15- 25 grams, 25-35 grams of Rhizoma Gastrodiae, 25-35 grams of Radix Codonopsis, 25-35 grams of Rhizoma Atractylodis Macrocephalae, 5-15 grams of red ginseng, 10-20 grams of radix achyranthis bidentatae, 10-20 grams of Radix Paeoniae Alba, 45-55 grams of jujube closes 10-20 grams of blood, 15-25 grams of the tuber of multiflower knotweed, 25-35 grams of fructus lycii, 15-25 grams of gentianae macrophyllae, 25-35 grams of rhizoma atractylodis, Cortex Eucommiae 15-25 grams, 15-25 grams of six sweat, 15-25 grams of Rhizoma Et Radix Notopterygii, 15-25 grams of safflower, 25-35 grams of dried orange peel, parasitism 15-25 grams, Radix Rehmanniae 25-35 Gram and 20-25 grams of radix rehmanniae preparata.
In this example, liquid medicine includes the Chinese medicine material of following parts by weight: 25 parts of radix bupleuri plus 25 parts of skin, 40 parts of Radix Astragali, life 20 parts of ginger, 25 parts of pollen, 20 parts of Yun Ling, 30 parts of Chinese yam, gallbladder careless 25 parts, 20 parts of Rhizoma Chuanxiong, radix saposhnikoviae 20 parts, 15 parts of Gui Zi, Radix Notoginseng 30 It is part, 30 parts of Radix Angelicae Sinensis, 10 parts of asarum, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Gastrodiae, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of red ginseng, 15 parts of radix achyranthis bidentatae, white 15 portions of Chinese herbaceous peony, closes 15 parts of blood, 20 parts of the tuber of multiflower knotweed, 30 parts of fructus lycii, 20 parts of gentianae macrophyllae, 30 parts of rhizoma atractylodis, 20 parts of Cortex Eucommiae, six sweat 20 at 50 parts of jujube Part, 20 parts of Rhizoma Et Radix Notopterygii, 20 parts of safflower, 30 parts of dried orange peel, 20 parts parasitic, 30 parts of Radix Rehmanniae and 25 parts of radix rehmanniae preparata.
The pharmacological action difference of above-mentioned various herbal raw materials is as follows:
Radix bupleuri: and in inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever；For cold, fever, fevers and chills alternate, chest side of body is swollen Bitterly, irregular menstruation, uterine prolapse, rectal prolapse.
Add skin: clearing heat and detoxicating, expelling wind and removing dampness is activated blood and relaxed tendons；For cold, fever, pharyngalgia, headache, pectoralgia of coughing, gastral cavilty Pain, diarrhea, dysentery, hypochondriac pain, jaundice, urolithiasis, leukorrhagia, rheumatic arthralgia, waist and leg ache, muscles and bones contraction, injury and bone fracture, Zha The cheek, acute mastitis, sore swollen toxin, snakebite and bugbite.
Radix Astragali: invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic；For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub- official Prolapsus, chronic rephrilis protinuria, diabetes, the long disunion of the open sore part.
Ginger: there are the multiple efficacies such as cold dispelling sweating, preventing phlegm from forming and stopping coughing, stomach function regulating, preventing or arresting vomiting.
Pollen: have moisturize, promote the production of body fluid, fall fire, quench the thirst, reduce swelling, apocenosis and other effects.
Yun Ling: eliminating dampness and diuresis；Strengthening the spleen and stomach；Antitoxic heart-soothing and sedative；For difficult urination；Edema swelling；Sip and cough；Vomiting； Spleen eating less；Diarrhea；Palpitation and restlessness；Insomnia forgetfulness；Spermatorrhea gonorrhoea.
Chinese yam: kidney-nourishing gas, strengthening the spleen and stomach.
Gallbladder grass: it is cold in nature, it is bitterly；It is clearing heat and detoxicating, cool blood detumescence, cough-relieving diuresis.
Rhizoma Chuanxiong:；Blood-activating and qi-promoting, wind-expelling pain-stopping.For irregular menstruation, amenorrhea and algomenorrhea, abdominal mass abdominal pain, pricking pain in the chest falls and flutters Swelling and pain, headache, rheumatic arthralgia.
Radix saposhnikoviae:；It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, relieving convulsion.
Gui Zi: middle benefit gas, stomach function regulating；For the cold pain of gastral cavilty, hiccup.
Radix Notoginseng: dissipating stasis and stanching bleeding, detumescence ding-tong；For spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen thorn Bitterly, tumbling and swelling.
Radix Angelicae Sinensis: replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels；For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, menostasis pain Through, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dry constipation of intestines.
Asarum: being used for wind-dispelling, cold dispelling, and row water the effect of having one's ideas straightened out, and has and controls air-cooled headache, nasosinusitis, dentalgia, phlegm retention cough It is inverse, rheumatic arthralgia.
Cortex Magnoliae Officinalis: gas consumption product；Eliminating dampness except full；Relieving asthma；For stagnation of QI due to dyspepsia；Abdominal distention constipation；Damp retention in middle-jiao, gastral cavity ruffian are spat It rushes down；Phlegm stops up the circulation of vital energy in the wrong direction；Chest full of cough.
Rhizoma Gastrodiae: relieve the wind syndrome, arresting convulsion；For dizziness pupil, cold and headache, extremity numbness, hemiplegia, aphasia, children Frightened epilepsy moves wind.
Radix Codonopsis: bowl spares, QI invigorating are promoted the production of body fluid；For weakness of the spleen and the stomach, qi-blood deficiency, the tired inability of body, deficiency of food is thirsty, chronic diarrhea, takes off Anus.
Rhizoma Atractylodis Macrocephalae: strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention；For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, Spontaneous perspiration, threatened abortion.
Red ginseng: blood-enrich is calmed the nerves with all worries set aside；For it is physically weak to be taken off, cold weak pulse of limb, Qi dysfunction in blood control, metrostaxis, heart failure It exhausts, cardiogenic shock.
Radix achyranthis bidentatae: blood circulation, nourishing liver and kidney, strengthening the bones and muscles, promoting diuresis for stranguria, (blood) downlink of igniting；For soreness of waist and knee joint, muscles and bones without Power, menostasis abdominal mass, dizziness due to hyperactivity of liver-YANG.
Radix Paeoniae Alba: calming the liver and relieving pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating；For headache and dizziness, hypochondriac pain, abdominal pain, four limbs contraction pain, the deficiency of blood It is sallow, irregular menstruation, spontaneous perspiration, night sweat.
Jujube: tonifying middle-Jiao and Qi, nourishing blood and tranquilization；For spleen eating less, loose stool out of strength, hysteria of womam.Prevent transfusion reaction, drop Low serum glutamic pyruvic transminase, antitumor, anti-oxidant, blood pressure lowering, norcholesterol, liver protecting improve immunity, prevent and treat brain blood supply Deficiency, antiallergy, anti-angiocardiopathy prevent and treat osteoporosis and anaemia.
Blood: dispelling wind promoting the dispersing function of the lung is closed, it is relieving cough and asthma；For catching a cold, cough, asthma.
The tuber of multiflower knotweed: help essence and blood (system is used)；Removing toxic substances, preventing malaria, relax bowel and defecation；Dizzy for blood and essence asthenia, beard and hair is early It is white, soreness and weakness of waist and knees, chronic malaria, ulcer, scrofula, dry constipation of intestines.
Fructus lycii: nourishing liver and kidney, benefiting shrewd head；For consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, the deficiency of blood withers Huang, blurred vision.
Gentianae macrophyllae: it is used for rheumatic arthralgia, apoplexy and hemiplegia, muscle arteries and veins contraction, skeletal pain, jaundice with damp-heat pathogen, osteopyrexia and fever to be small The fever of youngster's infantile malnutrition due to digestive disturbances or intestinalparasites.
Rhizoma atractylodis: drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight；For damp retention in middle-jiao, abdominal fullness and distention, diarrhea, oedema, tinea pedis impotence is preesed, Rheumatic arthralgia, anemofrigid cold, yctalopia, eyes dusk are puckery.
Cortex Eucommiae: there is nourishing liver and kidney, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination, the function of hypertension, miscarriage prevention Effect；There is different degrees of adjusting to make immune system, endocrine system, central nervous system, the circulatory system and urinary system With.
Six sweat: nourishing liver and kidney, strengthening the bones and muscles continue injured, only metrorrhagia and metrostaxis；For soreness and weakness of waist and knees, rheumatic arthralgia, metrorrhagia and metrostaxis, vaginal bleeding during pregnancy falls and flutters Damage.
Rhizoma Et Radix Notopterygii: relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic；For anemofrigid cold, wind-cold-dampness arthralgia, item strengthening tendons are anxious, joint ache, Geomantic omen edema, skin sore.
Safflower: blood circulation, removing blood stasis and acesodyne；For menostasis, dysmenorrhea, lochia, abdominal mass lump in the abdomen, chest impediment and cardialgia, the stasis of blood is stagnant Abdominal pain, pricking pain in the chest, injury from falling down, sore swell and ache curative.
Dried orange peel: regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm；For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
It is parasitic: to control nourishing liver and kidney；Strengthening the bones and muscles；Wind-damp dispelling, degrading the channel；Beneficial blood, miscarriage prevention；For soreness of waist and knee joint；Rheumatic arthralgia；Tire Dynamic uneasiness；It is hemiplegia；Tinea pedis；Wind-cold-dampness arthralgia；Vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.
Radix Rehmanniae: clearing heat and promoting fluid, cool blood, hemostasis；For consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, spot dermexanthesis is spitted blood, bleeding from five sense organs or subcutaneous tissue, throat Swelling and pain.
Radix rehmanniae preparata: yin-nourishing of enriching blood, life essence-filling, marrow-benefitting；For all cards of the deficiency of blood, such as blood deficiency chlorosis, dizziness, palpitaition, metrorrhagia leukorrhagia.
In the application, the medicinal material for preparing liquid medicine use includes radix bupleuri plus skin, Radix Astragali, ginger, pollen, Yun Ling, Chinese yam, gallbladder Grass, Rhizoma Chuanxiong, radix saposhnikoviae, Gui Zi, Radix Notoginseng, Radix Angelicae Sinensis, asarum, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, red ginseng, radix achyranthis bidentatae, Radix Paeoniae Alba, jujube, conjunction Blood, the tuber of multiflower knotweed, fructus lycii, gentianae macrophyllae, rhizoma atractylodis, Cortex Eucommiae, six sweat, Rhizoma Et Radix Notopterygii, safflower, dried orange peel, parasitism, Radix Rehmanniae and radix rehmanniae preparata.Above-mentioned medicinal material warp Reasonable compatibility is crossed, the distinctive performance of each raw material itself and effect are given full play to, and the complementation between taking into account, all medicines It shares, it is mutually compatible, meanwhile, by the superpower solvent properties of ethyl alcohol and efficacy-enhancing ingredient function, it is prepared for assisting in the treatment of rheumatism The liquid medicine of disease.The liquid medicine pharmacological property of the application is stable, safe and effective and drug effect plays comparatively fast.
The application also provides a kind of liquid medicine preparation method, is used to prepare above-mentioned liquid medicine comprising stock, medicine boils, medicine steeps, Medicine steaming, medicine wine, distillation and sealing process, below will be described in detail each process.
Procedure for preparation specifically includes: prepare required Chinese medicine material, it is spare after ground, mixing；It selects good available It is spare after being cleaned, being dried in the cereal crops of wine brewing.
In the application, the Chinese medicine material that uses are as follows: 20-25 grams of radix bupleuri plus 20-25 grams of skin, 35-45 grams of Radix Astragali, ginger 15- 25 grams, 20-25 grams of pollen, Yun Ling 15-25 gram, 25-35 grams of Chinese yam, 20-25 grams of gallbladder grass, 15-25 grams of Rhizoma Chuanxiong, radix saposhnikoviae 15-25 grams, Osmanthus is 5-25 grams sub-, 25-35 grams of Radix Notoginseng, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of asarum, 15-25 grams of Cortex Magnoliae Officinalis, 25-35 grams of Rhizoma Gastrodiae, Radix Codonopsis 25- 35 grams, 25-35 grams of Rhizoma Atractylodis Macrocephalae, 5-15 grams of red ginseng, 10-20 grams of radix achyranthis bidentatae, 10-20 grams of Radix Paeoniae Alba, 45-55 grams of jujube, close 10-20 grams of blood, 15-25 grams of the tuber of multiflower knotweed, 25-35 grams of fructus lycii, 15-25 grams of gentianae macrophyllae, 25-35 grams of rhizoma atractylodis, 15-25 grams of Cortex Eucommiae, 15-25 grams of six sweat, Rhizoma Et Radix Notopterygii 15-25 grams, 15-25 grams of safflower, 25-35 grams of dried orange peel, 15-25 grams parasitic, 25-35 grams of Radix Rehmanniae and 20-25 grams of radix rehmanniae preparata.
Those skilled in the art can adjust the dosage per Chinese medicine material simply according to actual needs, belong to the application's Protection scope.For example, in this example, the Chinese medicine material that uses are as follows: 25 parts of 25 parts of radix bupleuri plus skin, 40 parts of Radix Astragali, 20 parts of ginger, 25 parts of pollen, 20 parts of Yun Ling, 30 parts of Chinese yam, gallbladder careless 25 parts, 20 parts of Rhizoma Chuanxiong, radix saposhnikoviae 20 parts, 15 parts of Gui Zi, 30 parts of Radix Notoginseng, Radix Angelicae Sinensis 30 parts, 10 parts of asarum, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Gastrodiae, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of red ginseng, 15 parts of radix achyranthis bidentatae, 15 parts of Radix Paeoniae Alba, 50 parts of jujube closes 15 parts of blood, 20 parts of the tuber of multiflower knotweed, 30 parts of fructus lycii, 20 parts of gentianae macrophyllae, 30 parts of rhizoma atractylodis, 20 parts of Cortex Eucommiae, 20 parts of six sweat, Rhizoma Et Radix Notopterygii 20 parts, 20 parts of safflower, 30 parts of dried orange peel, 20 parts parasitic, 30 parts of Radix Rehmanniae and 25 parts of radix rehmanniae preparata.
In the application, the cereal crops used include one of paddy, sorghum, millet, corn, sweet potato or a variety of.This Field technical staff can select suitable cereal crops according to actual needs, belong to the protection scope of the application.For example, this In example, the cereal crops used are paddy and sorghum.
Medicine boiling procedure specifically includes: suitable quantity of water being added in Chinese medicine material and is decocted, and by filtered Chinese medicine medicine soup It is cooling, spare.Medicine boil technique for by the pharmacological property of Chinese medicine it is fried, make tanning liquid medicine be effectively maintained pharmacological property, and Titian Fume.In this example, water used in medicine boiling procedure is Ebony Hill mountain spring water.Ebony Hill mountain spring water is rich in minerals abundant and people Microelement needed for body itself is simply " good medicine ".In the present embodiment, medicine is boiled in technique, decocting time 4-6h.Ability Field technique personnel can adjust decocting time according to actual needs, for example, decocting time is 5h, belong to the protection model of the application It encloses.
Medicine bubble process specifically includes: clean cereal crops being poured into Chinese medicine medicine soup and are impregnated, after impregnating 25-45h, are carried out Filtering, cereal crops and filtered Chinese medicine medicine soup after being impregnated, wherein the cereal crops after immersion are used for subsequent medicine Technique is steamed, filtered Chinese medicine medicine soup storage makes technique to be ready for use on subsequent medicine.Medicine steeps technique and is used to seep the pharmacological property of Chinese medicine Enter in cereal crops.Those skilled in the art can adjust soaking time according to actual needs, for example, soaking time is 30h, Belong to the protection scope of the application.
Medicine steaming process specifically includes: the cereal crops after immersion being put into food steamer and carry out boiling.Medicine steaming technique is used for will Chinese medicine grain is cooked, wait ferment.In the present embodiment, the time that medicine steams is 4-6h.Those skilled in the art can be according to practical need Decocting time is adjusted, for example, it is 5h that medicine, which steams the time, belongs to the protection scope of the application.
Medicine is made process and is specifically included: being put into distiller's yeast after the cereal crops cooling after boiling, is put into fermentation after mixing evenly It ferments in cylinder, after fermentation 4-6 days, medicine is steeped filtered Chinese medicine medicine soup obtained in technique and poured into jar fermenter and is impregnated 25-30 days, cereal crops are pulled out out of jar fermenter, obtains liquid medicine stoste.
Distillation process specifically includes: after the cereal crops after fermentation, immersion are pulled out out of jar fermenter, liquid medicine stoste being put Enter and be boiled with soft fire 6-8h in food steamer in, distillation obtains liquid medicine.
Sealing process specifically includes: distillation being obtained liquid medicine and is put into wine vat sealing, is placed in shady place 25-40 days.Ability Field technique personnel can adjust Sealing period, such as 30 days according to actual needs, belong to the protection scope of the application.
The administration and dosage of the application liquid medicine: take finished product liquid medicine is oral to drink, 2-3 times daily, each 5-15ml.
Patient for taking the application liquid medicine tracks and records, and 100, sample, wherein patient with slight symptoms is 60, weight Disease patient is 40, and the criteria for classifying of mild and severe is the degree of dysarthrasis and the degree of limitation of activity.Adhere to taking this After applying for liquid medicine 0.5-1,42 patients have significant therapeutic effect, and affected joints swelling and pain are clearly better or limitation of activity journey Degree mitigates；35 patients have effective effect, and affected joints swelling and pain are alleviated.
Liquid medicine provided by the present application and preparation method thereof, cereal crops and Chinese medicinal material are boiled by medicine, medicine bubble, medicine steam, Medicine makes and distillation process, and the liquid medicine for assisting in the treatment of rheumatism is prepared, and the senile waist-leg pain of the liquid medicine centering, hand close Saving the diseases such as muscular atrophy, arthritis, rheumatism and rheumatoid has significant curative effect, and can effectively prevent palindromia.On the one hand, Using the superpower solvent properties of ethyl alcohol, the effective component in Chinese medicine is sufficiently leached out, pharmacological property is stable, safe and effective； On the other hand, using the efficacy-enhancing ingredient function of ethyl alcohol, drug effect is made to be not fully exerted, alleviates the slow problem of herbal nature, improved The practicability of Chinese medicine.In addition, the preparation method of the application liquid medicine is simple, and simplicity is taken, convenient for being widely used to promote.
Above-described the application embodiment does not constitute the restriction to the application protection scope.

Claims (8)

1. a kind of liquid medicine, for assisting in the treatment of person in middle and old age's property waist-leg pain, swivel of hand muscular atrophy, arthritis, rheumatism and rheumatoid Etc. diseases, which is characterized in that the Chinese medicine material including following parts by weight: 20-25 grams of radix bupleuri, plus 20-25 grams of skin, Radix Astragali 35- 45 grams, 15-25 grams of ginger, 20-25 grams of pollen, Yun Ling 15-25 gram, 25-35 grams of Chinese yam, 20-25 grams of gallbladder grass, 15-25 grams of Rhizoma Chuanxiong, Windproof 15-25 grams, Gui Zi 5-25 gram, 25-35 grams of Radix Notoginseng, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of asarum, 15-25 grams of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae 25- 35 grams, 25-35 grams of Radix Codonopsis, 25-35 grams of Rhizoma Atractylodis Macrocephalae, 5-15 grams of red ginseng, 10-20 grams of radix achyranthis bidentatae, 10-20 grams of Radix Paeoniae Alba, 45-55 grams of jujube, Close 10-20 grams of blood, 15-25 grams of the tuber of multiflower knotweed, 25-35 grams of fructus lycii, 15-25 grams of gentianae macrophyllae, 25-35 grams of rhizoma atractylodis, 15-25 grams of Cortex Eucommiae, six sweat 15-25 grams, 15-25 grams of Rhizoma Et Radix Notopterygii, 15-25 grams of safflower, 25-35 grams of dried orange peel, 15-25 grams parasitic, 25-35 grams of Radix Rehmanniae and radix rehmanniae preparata 20-25 grams.
2. liquid medicine according to claim 1, which is characterized in that the Chinese medicine material including following parts by weight: 25 parts of radix bupleuri, Add 25 parts of skin, 40 parts of Radix Astragali, 20 parts of ginger, 25 parts of pollen, 20 parts of Yun Ling, 30 parts of Chinese yam, 25 parts of gallbladder grass, 20 parts of Rhizoma Chuanxiong, radix saposhnikoviae 20 parts, 15 parts of Gui Zi, 30 parts of Radix Notoginseng, 30 parts of Radix Angelicae Sinensis, 10 parts of asarum, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Gastrodiae, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of red ginseng, 15 parts of Radix Paeoniae Alba, 50 parts of jujube, closes 15 parts of blood, 20 parts of the tuber of multiflower knotweed, 30 parts of fructus lycii, 20 parts of gentianae macrophyllae, rhizoma atractylodis at 15 parts of radix achyranthis bidentatae 30 parts, 20 parts of Cortex Eucommiae, 20 parts of six sweat, 20 parts of Rhizoma Et Radix Notopterygii, 20 parts of safflower, 30 parts of dried orange peel, 20 parts parasitic, 30 parts of Radix Rehmanniae and radix rehmanniae preparata 25 Part.
3. a kind of liquid medicine preparation method is used to prepare liquid medicine described in any one of the claims 1-2, which is characterized in that Including stock, medicine boils, medicine steeps, medicine steams, medicine is made and distillation process, wherein
Procedure for preparation specifically includes: prepare required Chinese medicine material, it is spare after ground, mixing；It selects good to can be used for making The cereal crops of wine, it is spare after being cleaned, being dried；
Medicine boiling procedure specifically includes: suitable quantity of water is added in Chinese medicine material and is decocted, and filtered Chinese medicine medicine soup is cooling, It is spare；
Medicine bubble process specifically includes: clean cereal crops being poured into Chinese medicine medicine soup and are impregnated, after impregnating 25-45h, were carried out Filter, cereal crops and filtered Chinese medicine medicine soup after being impregnated, wherein the cereal crops after immersion are steamed for subsequent medicine Technique, filtered Chinese medicine medicine soup storage make technique to be ready for use on subsequent medicine；
Medicine steaming process specifically includes: the cereal crops after immersion being put into food steamer and carry out boiling；
Medicine is made process and is specifically included: being put into distiller's yeast after the cereal crops cooling after boiling, is put into jar fermenter after mixing evenly It is sealed fermentation, after fermentation 4-6 days, medicine filtered Chinese medicine medicine soup obtained in technique is steeped and pours into seal in jar fermenter and is soaked Bubble 25-30 days, cereal crops are pulled out out of jar fermenter, obtain liquid medicine stoste；
Distillation process specifically includes: liquid medicine stoste being put into food steamer and is boiled with soft fire 6-8h in, distillation obtains liquid medicine.
4. liquid medicine preparation method according to claim 3, which is characterized in that the liquid medicine preparation method further includes sealing work Sequence, the sealing process specifically include: distillation being obtained liquid medicine and is put into wine vat sealing, is placed in shady place 25-40 days.
5. liquid medicine preparation method according to claim 3, which is characterized in that the cereal crops include paddy, sorghum, small One of rice, corn, sweet potato are a variety of.
6. liquid medicine preparation method according to claim 3, which is characterized in that water used in medicine boiling procedure is Ebony Hill mountain spring Water.
7. liquid medicine preparation method according to claim 3, which is characterized in that medicine boils in technique, decocting time 4-6h.
8. liquid medicine preparation method according to claim 3, which is characterized in that medicine steams in technique, digestion time 4-6h.
CN201910697546.XA 2019-04-23 2019-07-31 A kind of liquid medicine and preparation method thereof Pending CN110227142A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019103293331 2019-04-23
CN201910329333 2019-04-23

Publications (1)

Publication Number Publication Date
CN110227142A true CN110227142A (en) 2019-09-13

Family

ID=67855247

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910697546.XA Pending CN110227142A (en) 2019-04-23 2019-07-31 A kind of liquid medicine and preparation method thereof

Country Status (1)

Country Link
CN (1) CN110227142A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113930308A (en) * 2021-10-12 2022-01-14 河北味道府酒业有限责任公司 Health-preserving wine and brewing method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113930308A (en) * 2021-10-12 2022-01-14 河北味道府酒业有限责任公司 Health-preserving wine and brewing method thereof

Similar Documents

Publication Publication Date Title
US20180055898A1 (en) Traditional chinese medicine composition for preventing and treating externally diabetes and a method of using the same
CN102430079B (en) Traditional Chinese medicine composite for treating stranguria
CN101502582A (en) Composition for eliminating stagnation and promoting lactation and preparation method thereof
CN104873938A (en) Essence strengthening blood nourishing and youth retaining wine
CN105079551A (en) Traditional Chinese medicine composition for treating edema
CN101953989A (en) Electromagnetic wave vision rehabilitation instrument and Chinese medicinal composition
CN103735788A (en) Traditional Chinese medicine composition for treating edema
CN106214933A (en) A kind of decoction medicine treating kidney yang deficiency and Qi and blood deficiency and preparation method thereof
CN106266999A (en) A kind of Chinese medicine composition treating irritability and palpitation and insomnia and preparation method thereof
CN103394030B (en) Traditional Chinese medicine composition for treating depressed liver and deficient spleen
CN110227142A (en) A kind of liquid medicine and preparation method thereof
CN101953990B (en) Dynawave visual rehabilitation instrument and traditional Chinese medicine compound
CN104984186A (en) Traditional Chinese medicine tablet for treating diabetes and preparing method thereof
CN105031563A (en) Stasis removing wine
CN104225256A (en) Chinese medicine for treating fire toxin invagination type burning and preparation method
CN103463463A (en) Traditional Chinese medicine preparation for replenishing and activating blood and dispelling wind and removing dampness
CN103520410B (en) A kind of bone knitting powder
CN103495054B (en) Traditional Chinese medicine preparation for treating climacteric syndrome and preparation method thereof
CN106075278A (en) A kind of multi-functional Chinese medicine compositions
CN106267005A (en) A kind of decoction medicine treating chronic cystitis and preparation method thereof
CN104998241A (en) Astragalus membranaceus qi-tonifying traditional Chinese medicine liquor
CN105381333A (en) Traditional Chinese medicine composition with effects of treating spleen-kidney Yang deficiency
CN104740193A (en) Traditional Chinese medicine composition for treating neck-shoulder muscle strain syndrome and preparation method of traditional Chinese medicine composition
CN105012905A (en) Liquor capable of tonifying deficiency, nourishing blood and dredging collaterals
CN104940722A (en) Sperm generating, menstruation regulating and kidney tonifying wine

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20190913

RJ01 Rejection of invention patent application after publication