CN102885896A - Medicine for treating thromboangitis obliterans - Google Patents

Medicine for treating thromboangitis obliterans Download PDF

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CN102885896A
CN102885896A CN2012104376274A CN201210437627A CN102885896A CN 102885896 A CN102885896 A CN 102885896A CN 2012104376274 A CN2012104376274 A CN 2012104376274A CN 201210437627 A CN201210437627 A CN 201210437627A CN 102885896 A CN102885896 A CN 102885896A
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medicine
radix
rhizoma
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CN102885896B (en
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王向飞
王雷子
秦兴娜
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Abstract

The invention discloses a medicine for treating thromboangitis obliterans. The medicine is prepared from the following ingredients by weight: 10-90 grams of honeysuckle, 10-20 grams of polygala tenuifolia, 3-10 grams of ligusticum chuanxiong, 3-12 grams of radix bupleuri, 3-12 grams of radix scutellariae, 3-18 grams of astragalus, 3-13 grams of safflower, 3-13 grams of angelica sinensis, 3-13 grams of forsythia, 3-13 grams of poria cocos, 3-15 grams of schizonepeta and 3-9 grams of liquorice. The medicine has the functions of warming channel to remove coldness, promoting circulation and removing stasis, regulating vital energy and stopping pain, so that the purposes of controlling the disease development, avoiding amputation, relieving pain of patients and lowering the treatment cost are achieved. The medicine further has the characteristics that taking is convenient, carrying is easy and side effects are small.

Description

A kind of medicine for the treatment of thromboangiitis obliterans
Technical field
The invention belongs to the Chinese medicine product technical field, what relate generally to is a kind of medicine for the treatment of thromboangiitis obliterans.
Background technology
Thromboangiitis obliterans, the traditional Chinese medical science are called it " gangrene of finger or toe ".This kind disease has acute, subacute and chronic and general angiopathy.A kind of chronic, occlusive, diseases associated with inflammation that occurs in peripheral vessels, how with the Secondary cases neuropathy, mainly betide extremity in, small artery and vein, especially common with lower limb.Clinical symptoms is pressed the limb ischemia degree, can be divided into for three phases: 1, the ischemia phase: vasculitic symptom is suffered from acroanesthesia, is sent out cool, slight intermittent claudication, the migration superficial phlebitis can repeatedly occur.Check and find that trouble limb skin temperature is slightly low, color and luster is paler, and instep or posterior tibial artery are beaten and weakened.This phase, functional (spasm) was greater than apparatus factors.2, the malnutrition phase: vasculitic clinical symptoms suffers from acroanesthesia, it is cool to send out, be afraid of cold, intermittent claudication increases the weight of, and rest pain is arranged.Suffer from that limb skin often is flushing color, aubergine or pale asphyxia, pedal skin drying, decortication, toenail poor growth, thickens distortion, fine hair comes off, Calf muscle has the atrophy phenomenon, the disappearance of trouble main drive arteriopalmus.The uneasiness of can being in a bad mood, dizzy lumbago, the disease that muscles and bones is soft.3, the downright bad phase: symptom continues to increase the weight of, and the vasculitis symptom is suffered from limb toe (finger) end blackout, gangrene, ulcer, and sharp ache is persistence.This phase tremulous pulse entirely shuts, and side Zhi Xunhuan can not guarantee toe (finger) survival.
The generation of primary disease, in cold, smoking, drink, wound, the factor such as excited is relevant, and the imbalance of autonomic nervous system feature capability and Endocrine Activity (cause medium and small continuous vessel spasm such as suprarenalism unusually, the blood vessel wall malnutrition causes the pathological changes such as thrombosis and lumen of vessels obturation at last).Chinese medicine is thought primary disease mainly due to being subjected to cold-damp outward, so that cold-damp cohesion meridians obturation is obstructed, and QI-blood circulation does not freely form, and the operation of cold-damp cohesion meridian qi and blood is obstructed, and then shows extremity not warm; Congealing cold with blood stasis, venation blocking barrier, stagnation of QI and blood may bring about pain; The strongly fragrant heat-transformation of a specified duration of cold-damp, the corruption of intenseness of heat meat then forms ulcer, gangrene, gangrene more because of excessive noxious heat, the symptom of impairment of YIN often occurs, and later stage toe (finger) osteonecrosis comes off, because pus is dripping more than, does not close up for a long time, the QI and blood deficiency symptom can occur again.
At present, the clinical treatment means of taking mainly is operative treatment: 1. breast or lumbar sympathectomy are applicable to early stage patient; 2. adrenalectomy.After sympathectomy, can not the take action patients with terminal of arteries and veins Reconstruction, feasible adrenalectomy, also sympathectomize joint in the lump; 3. arterial thrombus Endarterectomy; 4. arterial bypass; 5. omentum grafting divides pedicle graft and free grafting, by hypodermic tunnel, nethike embrane is pulled to far-end of limb successively; 6. limbs vein arterial revascularization operation.Although above-mentioned treatment means can play certain therapeutical effect, it can not fundamentally be cured to damage other organ as cost, and treatment cost is high, and is painful large, also must carry out amputation when serious to the later stage and save life from damage.
Summary of the invention
The objective of the invention is to propose a kind of medicine for the treatment of thromboangiitis obliterans.Have dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, the function of regulating the flow of vital energy and relieving the pain reaches the control PD, avoids amputation, alleviates the patient suffering, reduces the purpose of medical expense.Also have taking convenience, portable, the characteristics that side effect is little.
The present invention realizes that the technical scheme that above-mentioned purpose is taked is: a kind of medicine for the treatment of thromboangiitis obliterans,
Made by following component, consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams.
Also can add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae component in the said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams.
Also can add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae, Radix Achyranthis Bidentatae component in the said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, Radix Achyranthis Bidentatae 3-12 grams.
Also can add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae, pollen component in the said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, pollen 3-13 grams.
Also can add Semen Cassiae in the said medicine, add Herba Epimedii, Semen Vaccariae, Rhizoma Corydalis component, consumption is weight portion: Semen Cassiae 3-15 grams add Herba Epimedii 3-10 grams, Semen Vaccariae 3-12 grams, Rhizoma Corydalis 3-15 grams.
Also can add Rhizoma Cimicifugae, Ramulus Cinnamomi, Fructus Chaenomelis component in the said medicine, consumption is weight portion: Rhizoma Cimicifugae 3-12 gram Ramulus Cinnamomi 3-12 gram Fructus Chaenomeliss 3-12 grams.
Invention can be made oral liquid, granule, tablet, pill and capsule etc. by traditional handicraft.
The principle of controlling is executed in invention according to differential diagnosis in tcm, for the initial stage symptom: the patient has limbs heavy, is afraid of cold feeling of numbness, toes have stabbing pain, and shank has the tic phenomenon, and begin to occur the lame property of intermittence, and the pain increased after the finger hands was cold, pulsation of foot dorsal artery weakens unable, white and greasy fur, deep-thready pulse and late.With dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, regulating the flow of vital energy relieves the pain is the Therapeutic Principle, mainly by Flos Lonicerae, Radix Polygalae, Rhizoma Chuanxiong, Radix Bupleuri, Radix Scutellariae, the Radix Astragali, Flos Carthami, Radix Angelicae Sinensis, Fructus Forsythiae, Poria, Herba Schizonepetae is in the medicine of the treatment thromboangiitis obliterans that Radix Glycyrrhizae forms, add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae component, go to add the pollen component between finger if focus occurs in; Focus generation toe section then adds the Radix Achyranthis Bidentatae component.
For the symptom in mid-term; The state of an illness is more of a specified duration, and local skin feels cold, and suffers from limb and raises then skin color slightly HUANGBAI(sic) is a little, then black purple when sagging, the dark red pain of some skin colors transfers persistence to, difficulty in walking, suffer from the gradually atrophy of limb muscle, the toenail thickening, arteriopalmus disappears or is faint, with dizziness, pain in the lumbar region, the muscles and bones soft Liver and kidney virtual image that waits that withers, the local vascular total blockage, the blood vessel blood supply stops to necrose, downright bad toes or the foot of being confined to more, mostly occurring merges the muscle of leg of quite a few moist necrosis moist necrosis for mummification necrosis, secondary infection occurs, after the trouble limb festers, the wound surface disunion, sharp ache, even fervescence, rapid pulse can appear.With physical strength profiting, bone and muscle strengthening, wound healing, invigorate blood circulation and control the painful Therapeutic Principle that is, mainly by Flos Lonicerae, Radix Polygalae, Rhizoma Chuanxiong, Radix Bupleuri, Radix Scutellariae, the Radix Astragali, Flos Carthami, Radix Angelicae Sinensis, Fructus Forsythiae, Poria, Herba Schizonepetae, in the medicine of the treatment thromboangiitis obliterans that Radix Glycyrrhizae forms, add Semen Cassiae, add Herba Epimedii, Semen Vaccariae, Rhizoma Corydalis component.Semen Cassiae directly enters Liver Channel, and add Herba Epimedii and enter kidney channel and consolidate key medicine, the physical strength profiting bone and muscle strengthening, Semen Vaccariae directly enters two large blood through the network of the heavy warp of conscience.When thromboangitis obliterans occurring such as finger position, add again Rhizoma Cimicifugae, Ramulus Cinnamomi, Fructus Chaenomelis, Rhizoma Corydalis component.Invigorating blood circulation, it is painful to control.
The present invention is by treatment and research to " thromboangiitis obliterans " (traditional Chinese medical science is called it " necrosis "), obvious effective rate to treatment " necrosis is sick " (thromboangitis obliterans) can reach more than 98%, cure rate can reach about 95%, usage is simple, curative effect is fast, can relieve the pain in 5-10 days, and be difficult for recurrence after curing.
Model case is as follows:
Ma, woman, 27 years old.In JIUYUE, 2003 onset; Be diagnosed as: " thromboangiitis obliterans ".By failing to respond to any medical treatment, increase the weight of on the contrary whole body swelling, color is deceived purple hurt like hell, can not walk, be paralyzed in bed, be forced to suspend schooling, take the Chinese medicine decoction after course for the treatment of, the state of an illness is under control, and is clearly better, the walking of can leaving the bed, skin color has also become normally, rear continuous use after four courses for the treatment of the state of an illness cure fully.Go to Japan to study abroad pursuit of advanced studies after recovering, healthy so far.
Cattle, woman, 73 years old.In October, 2005 onset, examination in hospital is diagnosed as " thromboangiitis obliterans ".This patient's focus occurs in upper limb, and PD is very fast, and both hands refer to highly rot blackening, the large section of slough comes off, and phalanges exposes, the long stream of pus, distribute a burst of stink, hurt like hell, night, pain was even more serious, can not get sufficient sleep, with a haggard face, gloomy unglazed, painful bitter face faces at any time and clips both hands even life-threatening serious consequence, has spent the wholesale expenses for medicine, fail to respond to any medical treatment, return in to the home.Take the Chinese medicine decoction after course for the treatment of, the state of an illness has obtained effective control, and dead skin comes off gradually, grows new granulation tissue, pain has also been alleviated, after continuous 5 courses for the treatment of, the state of an illness is cured fully, has recovered finger function, her complete limbs have been kept, saved her life, healthy so far, have no recurrence.
Lee, man, 75 years old.In October, 2008, onset was diagnosed as " thromboangiitis obliterans " (Takayasu arteritis).Invalid after one section of hospitalize, aggravation has been spent the wholesale expenses for medicine on the contrary, patient's dim complexion, and face dolorosa, the toe blackout is rotted, and the long stream of pus gives out a burst of stink, faces at any time the possibility of amputation.Take the Chinese medicine decoction after course for the treatment of, pain is under control, and it is normal that the color of toe is also recovered gradually, and wound also begins healing, and pus is also few.After the treatment through 6 courses for the treatment of, the state of an illness is cured rehabilitation fully, healthyly so far has no recurrence.
The specific embodiment
The present invention further is elaborated in the mode of embodiment, but the present invention does not limit to following examples:
Embodiment 1
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams.
Embodiment 2
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams, Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams.
Embodiment 3
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams, Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, Radix Achyranthis Bidentatae 3-12 grams.
Embodiment 4
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams, Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, pollen 3-13 grams.
Embodiment 5
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams, Semen Cassiae 3-15 grams, add Herba Epimedii 3-10 grams, Semen Vaccariae 3-12 grams, Rhizoma Corydalis 3-15 grams.
Embodiment 5
A kind of medicine for the treatment of thromboangiitis obliterans is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams, Rhizoma Cimicifugae 3-12 grams, Ramulus Cinnamomi 3-12 gram Fructus Chaenomeliss 3-12 grams.

Claims (7)

1. medicine for the treatment of thromboangiitis obliterans, it is characterized in that: it is made by following component, and consumption is weight portion: Flos Lonicerae 10-90 grams, Radix Polygalae 10-20 grams, Rhizoma Chuanxiong 3-10 grams, Radix Bupleuri 3-12 grams, Radix Scutellariae 3-12 grams, the Radix Astragali 3-18 grams, Flos Carthami 3-13 grams, Radix Angelicae Sinensis 3-13 grams, Fructus Forsythiae 3-13 grams, Poria 3-12 grams, Herba Schizonepetae 3-15 grams, Radix Glycyrrhizae 3-9 grams.
2. the medicine for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae component in said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams.
3. the medicine for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae, Radix Achyranthis Bidentatae component in said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, Radix Achyranthis Bidentatae 3-12 grams.
4. the medicine for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: add Rhizoma Et Radix Notopterygii, clinopodium grass, Caulis Akebiae, pollen component in said medicine, consumption is weight portion: Rhizoma Et Radix Notopterygii 3-12 grams, clinopodium grass 3-20 grams, Caulis Akebiae 3-13 grams, pollen 3-13 grams.
5. the medicine for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: in said medicine, add Semen Cassiae, add Herba Epimedii, Semen Vaccariae, Rhizoma Corydalis component, consumption is weight portion: Semen Cassiae 3-15 grams, add Herba Epimedii 3-10 grams, Semen Vaccariae 3-12 grams, Rhizoma Corydalis 3-15 grams.
6. the medicine for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: add Rhizoma Cimicifugae, Ramulus Cinnamomi, Fructus Chaenomelis component in said medicine, consumption is weight portion: Rhizoma Cimicifugae 3-12 gram Ramulus Cinnamomi 3-12 gram Fructus Chaenomeliss 3-12 grams.
7. according to claim 1 and 2 or 3 or 4 or the medicine of 6 or 6 described treatment thromboangiitis obliteranss, it is characterized in that: described medicine is oral liquid, granule, tablet, pill and capsule.
CN201210437627.4A 2012-11-06 2012-11-06 Medicine for treating thromboangitis obliterans Active CN102885896B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288392A (en) * 2015-11-30 2016-02-03 吕翠云 Traditional Chinese medicine for treating thromboangiitis obliterans
CN105497654A (en) * 2016-01-29 2016-04-20 丁云龙 Traditional Chinese medicine for treating thromboangiitis obliterans
CN105749012A (en) * 2016-04-29 2016-07-13 张雪燕 Pharmaceutical composition for treating thrombotic diseases and application thereof
CN113456734A (en) * 2021-07-30 2021-10-01 张明之 Formula for treating thromboangiitis obliterans

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288392A (en) * 2015-11-30 2016-02-03 吕翠云 Traditional Chinese medicine for treating thromboangiitis obliterans
CN105497654A (en) * 2016-01-29 2016-04-20 丁云龙 Traditional Chinese medicine for treating thromboangiitis obliterans
CN105749012A (en) * 2016-04-29 2016-07-13 张雪燕 Pharmaceutical composition for treating thrombotic diseases and application thereof
CN113456734A (en) * 2021-07-30 2021-10-01 张明之 Formula for treating thromboangiitis obliterans

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