CN103041361B - Medicament for treating three-high disease (high cholesterol, high blood pressure, high blood sugar) and preparation method thereof - Google Patents

Abstract

The invention provides a medicament for treating three high diseases (high cholesterol, high blood pressure, high blood sugar) and a preparation method thereof. The medicament is formed by mixing 24 Chinese herb medicines such as unprocessed monkshood, tribulus terrestris, pseudo-ginseng, black aconite, hawthorn, prepared fleece flower roots, cherokee rose fruits, apocynum venetum, leech, fried jujube kernel. The preparation method comprises the following steps of: pulverizing the medicines to be fine powder or performing water decoction to extract and prepare a thick paste; adding conventional auxiliary materials into the thick paste to prepare different preparations. According to the medicament, by virtue of scientific matching of the multiple medicines and comprehensive treatment, the effective components of the medicament can rapidly enter a blood circulating system to clear away lipid and cholesterol stagnated in a vessel, promote excretion, inhibit aggregation of blood cells, reduce arteriosclerosis and anti-thrombosis, and improve functions of organs, so that the three-high disease can be cured quickly, and patients can be recovered.

Description

A kind of medicine for the treatment of three-hypers disease and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine for the treatment of three-hypers disease and preparation method thereof.

Background technology

Three-hypers disease refers to hypertension, hyperglycemia, hyperlipidemia, and they are " affluenza " that modern society is derived from, and possible individualism also may be interrelated.Three-hypers disease can have no symptom in early days, and also no abnormalities feel is usually just found when doing physical examination, and as found not in time, this disease develops into and can form serious disease, even threat to life late period.

Hypertension is a kind ofly to take arteriotony and continue to raise be often to cause the chronic disease of main manifestations the pathological changes of the vitals such as the heart, brain, kidney and to occur corresponding consequence.Can show as in early days headache, dizziness, tinnitus, cardiopalmus, dim eyesight, the symptom such as absent minded, later stage blood pressure often continues in higher level, and impaired with organs such as brain, the heart, kidneys.

Hyperglycemia, is because insulin is relatively or definitely not enough, makes a kind of chronic, the lifelong property disease of the nutrient Developmental and Metabolic Disorder such as carbohydrate, fat, protein in body.This disease can cause multiple complications, when serious, can cause systemic disease, makes that people is disabled, blinding, even lethal.

Hyperlipidemia can give rise to diseases, and comprises coronary atherosclerosis, heart infarction, hypertensive cardiopathy, cardiomyopathy, cerebrovascular, cerebral arteriosclerosis, cerebral thrombosis, liver cirrhosis, renal arteriosclerosis, diabetes etc., serious harm people life and health.

The most of supply in the market takes multi-medicament just for the medicine of a certain single disease in three-hypers disease for the needs of patients of suffering from the various disease conditions in hypertension, hyperlipidemia, hyperglycemia simultaneously simultaneously, to patient, brought great inconvenience.These medicines are generally in the majority with Western medicine, although the rapid relief of symptoms of Western medicine, relapse rate is high, and will rebound after drug withdrawal, must uninterruptedly take medicine for a long time, to patient with larger financial burden.Meanwhile, Western medicine toxic and side effects is larger, and long-term prescription also can cause certain infringement to patient body.

Summary of the invention

The technical problem to be solved in the present invention is to provide a kind of medicine for the treatment of three-hypers disease and preparation method thereof, and this medicine has the blood pressure of tune, blood fat reducing, hypoglycemic effect, and rapid-action, lasting medicine, does not recur and do not rebound after drug withdrawal, safe without toxic side effect.

Technical scheme provided by the invention is a kind of medicine for the treatment of three-hypers disease, and it is made by the raw material of following weight portion:

500～1000 parts of Radix Aconiti Lateralis, 500～1000 parts of Fructus Tribulis, 540～1000 parts, Radix Notoginseng, 100～400 parts of Radix Aconiti Lateralis Preparatas, 500～1000 parts of Fructus Crataegis, 250～500 parts of Radix Polygoni Multiflori Preparata, 250～500 parts of Fructus Rosae Laevigatae, 250～500 parts of Herba Apocyni venetis, 180～360 parts of Hirudos, 450～900 parts of Semen Ziziphi Spinosae (parched)s, 300～600 parts of Rhizoma Acori Graminei, 300～600 parts of Rhizoma Chuanxiongs, 900～1000 parts of Caulis Polygoni Multiflori, 450～900 parts of Concha Ostreaes, 300～600 parts of Radix Angelicae Sinensis, 500～1000 parts of Radix Salviae Miltiorrhizaes, 250～500 parts of Concretio silicea Bambusae seu schizostachyi, 250～500 parts of Cortex Lycii, 250～500 parts, sulfur, 500～1000 parts of Radix Ilicis Pubescentiss, 50～100 parts of Herba Asaris, 100～300 parts of Ramulus Cinnamomi, 100～200 parts of Cortex Cinnamomis, 100～200 parts of Rhizoma Zingiberiss.

Preferred weight part of above-mentioned raw materials is:

800 parts of Radix Aconiti Lateralis, 700 parts of Fructus Tribulis, 850 parts, Radix Notoginseng, 250 parts of Radix Aconiti Lateralis Preparatas, 700 parts of Fructus Crataegis, 370 parts of Radix Polygoni Multiflori Preparata, 390 parts of Fructus Rosae Laevigatae, 400 parts of Herba Apocyni venetis, 280 parts of Hirudos, 750 parts of Semen Ziziphi Spinosae (parched)s, 450 parts of Rhizoma Acori Graminei, 400 parts of Rhizoma Chuanxiongs, 950 parts of Caulis Polygoni Multiflori, 800 parts of Concha Ostreaes, 500 parts of Radix Angelicae Sinensis, 700 parts of Radix Salviae Miltiorrhizaes, 400 parts of Concretio silicea Bambusae seu schizostachyi, 350 parts of Cortex Lycii, 380 parts, sulfur, 750 parts of Radix Ilicis Pubescentiss, 80 parts of Herba Asaris, 200 parts of Ramulus Cinnamomi, 160 parts of Cortex Cinnamomis, 150 parts of Rhizoma Zingiberiss.

The medicine for the treatment of three-hypers disease of the present invention, its dosage form can be medically acceptable any dosage form, can be specifically pill, granule or capsule.

The present invention also provides the preparation method of the medicine of above-mentioned treatment three-hypers disease, comprises the following steps:

1) by formula, take each raw material for standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 8～12 times of the weight of feeding intake to boil 1～2h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form fine powder standby;

4) sulfur is ground to form to fine powder standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 1～3 time, the water that at every turn adds 6～20 times of raw material gross weights, each 1～2h that decocts, merge decoction liquor, filter medicinal residues, the extractum that when filtrate is concentrated into 50～70 ℃, relative density is 1.06～1.14, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, make as required different preparations, it can be specifically pill, granule or capsule.

Granularity 100～300 orders of fine powder described in the step 3) of said method and step 4).

The pharmaceutical characteristic of each raw material of the present invention is:

Radix Aconiti Lateralis, acrid in the mouth, sweet, extremely hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, supporing yang, the dispersing cold for relieving pain of benefit fire;

Fructus Tribuli, acrid in the mouth, hardship, slightly warm in nature, returns Liver Channel, suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic;

Radix Notoginseng, sweet in the mouth, micro-hardship, warm in nature, return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel, hemostasis, loose blood, analgesic therapy;

Radix Aconiti Lateralis Preparata, acrid in the mouth, sweet, extremely hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by wind-cold damp pathogen;

Fructus Crataegi, sweet in the mouth, acid, slightly warm in nature, enters spleen, stomach, Liver Channel, promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, convergence dysentery relieving;

Radix Polygoni Multiflori Preparata, bitter in the mouth, sweet, puckery, warm in nature, flat, returns liver, the heart, kidney channel, invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, the turbid blood fat reducing of change;

Fructus Rosae Laevigatae, sour in the mouth, sweet, puckery, property is flat, returns kidney, bladder, large intestine channel, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, stopping leak dysentery, urine reducing;

Herba Apocyni veneti, sweet in the mouth, micro-hardship, cool in nature, return Liver Channel, heat clearing away suppressing the hyperactive liver, inducing diuresis to remove edema;

Hirudo, master gathers by stagnant blood, blood stasis, removing blood stasis removing food stagnancy;

Semen Ziziphi Spinosae (parched), sweet in the mouth, acid, property is flat, GUIXIN warp, spleen channel, Liver Channel, gallbladder meridian, mind tranquilizing and the heart calming, nourishing the liver, arresting sweating;

Rhizoma Acori Graminei, acrid in the mouth, hardship, warm in nature, GUIXIN, stomach warp, removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae;

Rhizoma Chuanxiong, acrid in the mouth, warm in nature, returns liver, gallbladder, pericardium channel, blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping;

Caulis Polygoni Multiflori, sweet in the mouth, micro-hardship, property is flat, nourishes heart, calms the nerves, dredging collateral, dispels the wind;

Concha Ostreae, salty in the mouth, cold nature, return liver, gallbladder, kidney channel, convergence, calmness, removing toxic substances, analgesia;

Radix Angelicae Sinensis, sweet in the mouth, hardship, pungent, warm in nature, return liver, the heart, spleen channel, menstruction regulating and pain relieving, moisturize laxation;

Radix Salviae Miltiorrhizae, bitter in the mouth, property is flat, tepor, enters the heart, Liver Channel, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind;

Concretio silicea Bambusae seu schizostachyi, acrid in the mouth, property are put down, and enter lung, Liver Channel, relieving cough and reducing sputum, regulating QI to relieve pain, relieving convulsion;

Cortex Lycii, sweet in the mouth, cold in nature, enters lung, liver, kidney channel, and removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing;

Sulfur, sour in the mouth, warm in nature, takes orally and can mend fire, supporing yang, relieving constipation;

Radix Ilicis Pubescentis, mildly bitter flavor, sweet, property is flat, enters lung, liver, large intestine channel, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, expelling phlegm for arresting cough;

Herba Asari, acrid in the mouth, warm in nature, returns lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel, the cold expelling that induces sweat, wind-expelling pain-stopping, warming the lung to resolve fluid-retention, sensible;

Ramulus Cinnamomi, acrid in the mouth, sweet, warm in nature, enter liver, kidney, urinary bladder channel, expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI;

Cortex Cinnamomi, acrid in the mouth, sweet, extremely hot in nature, returns kidney, spleen, the heart, Liver Channel, diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian;

Rhizoma Zingiberis, acrid in the mouth, hot in nature, returns spleen, stomach, the heart, lung meridian, and warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.

The instructions of taking of medicine of the present invention is: take the medicine that is equivalent to crude drug 6～18g weight every day, minute take for 3 times, cold boiled water takes, in ante cibum or to take effect half an hour after meal better, within 30 days, be a course for the treatment of, most of patient takes 3 courses for the treatment of and can cure.

The kinds of traditional Chinese medicines taste raw material that adopts of the present invention, science compatibility, comprehensive measure, can make effective ingredient enter rapidly blood circulation, short time intramedullary expansion vessel softening, increase blood vessel elasticity, increase blood vessel perfusion flow, remove the lipid and the cholesterol that in blood vessel, are retarded by silt, blocking-up thrombosis, suppress hematoblastic gathering, alleviate arteriosclerosis, and then recovery liver, kidney, the heart, the normal physiological function of each organ such as brain, there is good blood pressure lowering, blood fat reducing, blood sugar lowering, prevent arteriosclerosis, improve sanguimotor effect, cardiovascular and cerebrovascular disease is had to good preventive and therapeutic effect.The present invention is pure Chinese medicinal preparation, takes rear active substance and discharges rapidly, absorbs complete, lasting medicine, there will not be bounce-back, safe without toxic side effect after drug withdrawal.

The specific embodiment

The invention will be further described for following specific embodiment, but not as a limitation of the invention.

Embodiment 1

1) by the proportioning of embodiment 1 in following table 1, take each raw material, standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 8 times of the weight of feeding intake to boil 1h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form 100 order fine powders standby;

4) sulfur is ground to form to 100 order fine powders standby;

5) Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and be placed in container, add the decocting of 6 times of inventorys to boil 1h, filter, obtain decoction liquor; Decoction liquor is filtered to medicinal residues, gets the filtrate extractum that relative density is 1.06 while being concentrated into 50 ℃, then add fine powder and the step 2 of step 3) and step 4)) filtrate, mix, add conventional excipients, dry, pulverize, incapsulate, make capsule.

Embodiment 2

1) by the proportioning of embodiment 2 in following table 1, take each raw material, standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 12 times of the weight of feeding intake to boil 2h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form 300 order fine powders standby;

4) sulfur is ground to form to 300 order fine powders standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 3 times, the water that at every turn adds 20 times of raw material gross weights, each 2h that decocts, merge three times decoction liquor, filter medicinal residues, the extractum that when filtrate is concentrated into 70 ℃, relative density is 1.14, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, add conventional excipients, granulate, dry, granulation agent.

Embodiment 3

1) by the proportioning of embodiment 3 in following table 1, take each raw material, standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 10 times of the weight of feeding intake to boil 1.5h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form 200 order fine powders standby;

4) sulfur is ground to form to 200 order fine powders standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 2 times, add for the first time the decocting of 15 times of raw material gross weights to boil 1.5h, add for the second time the decocting of 8 times of medical material gross weights to boil 1h, merge decoction liquor twice, filter medicinal residues, the extractum that when filtrate is concentrated into 60 ℃, relative density is 1.12, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, add conventional excipients, make ball, make pill.

Embodiment 4

1) by the proportioning of embodiment 4 in following table 1, take each raw material, standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 8 times of the weight of feeding intake to boil 2h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form 100 order fine powders standby;

4) sulfur is ground to form to 300 order fine powders standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 3 times, add for the first time the decocting of 20 times of raw material gross weights to boil 2h, add for the second time the decocting of 10 times of raw material gross weights to boil 1.5h, add for the third time the decocting of 6 times of raw material gross weights to boil 1h, merge three times decoction liquor, filter medicinal residues, the extractum that when filtrate is concentrated into 70 ℃, relative density is 1.06, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, add conventional excipients, tabletting, make tablet.

Table 1

Raw material	Embodiment 1(g)	Embodiment 2(g)	Embodiment 3(g)	Embodiment 4(g)
					Radix Aconiti Lateralis	500	1000	800	500
Fructus Tribuli	500	1000	700	1000
					Radix Notoginseng	540	1000	850	540
Radix Aconiti Lateralis Preparata	100	400	250	400
					Fructus Crataegi	500	1000	700	500
Radix Polygoni Multiflori Preparata	250	500	370	500
					Fructus Rosae Laevigatae	250	500	390	250
Herba Apocyni veneti	250	500	400	500
					Hirudo	180	360	280	180
Semen Ziziphi Spinosae (parched)	450	900	750	900
					Rhizoma Acori Graminei	300	600	450	300
Rhizoma Chuanxiong	300	600	400	600
					Caulis Polygoni Multiflori	900	1000	950	900
Concha Ostreae	450	900	800	900
					Radix Angelicae Sinensis	300	600	500	300
Radix Salviae Miltiorrhizae	500	1000	700	1000
					Concretio silicea Bambusae seu schizostachyi	250	500	400	250
Cortex Lycii	250	500	350	500
					Sulfur	250	500	380	250

Radix Ilicis Pubescentis	500	1000	750	1000
					Herba Asari	50	100	80	50
Ramulus Cinnamomi	100	300	200	300
					Cortex Cinnamomi	100	200	160	100
Rhizoma Zingiberis	100	200	150	200

Use and the therapeutic effect of medicine of the present invention are described below in conjunction with concrete case.

Model case:

1, Xu Weizhen, female, 65 years old, because hypertension causes dizziness, headache, 10 years uncomfortable in chest, through multi-treatment, do not take a turn for the better, and day then increase the weight of, during walking, there is the symptoms such as dyspnea, palpitating speed.In March 5 in 2008 Nikkei hospital diagnosis be 2 phases of hypertension, left side blood pressure 180/110 millimetres of mercury, right side blood pressure 170/110 millimetres of mercury.June 5 in 2008, Nikkei was taken 3 courses for the treatment of of medicine of the embodiment of the present invention 1, and transference cure, follows up a case by regular visits to and have no recurrence.

2, Huang Zhiwei, man, 54 years old, suffer from hypertension and have a surplus for 5 years, during left breast, there is acupuncture sample pain, and with symptoms such as uncomfortable in chest, dizzy, headaches.In June 3 in 2007 Nikkei hospital diagnosis be 2 phases of hypertension, left side blood pressure 170/110 millimetres of mercury, right side blood pressure 170/105 millimetres of mercury.The medicine of taking the embodiment of the present invention 2 on August 12nd, 2007, transference cure after 2 months, follows up a case by regular visits to and has no recurrence.

3, Li Yongfu, man, 75 years old, on October 26th, 2010 because of headache, dizzy, uncomfortable in chestly send doctor medical, be diagnosed as 2 phases of hypertension and with hyperlipidemia and hypercholesterolemia, left side blood pressure 220/140 millimetres of mercury, right side blood pressure 190/130 millimetres of mercury.The medicine of taking the embodiment of the present invention 3 on November 5th, 2010, transference cure after 60 days, follows up a case by regular visits to and has no recurrence.

4, Xie Huihong, female, 58 years old, frequent dizziness headache over more than 10 years, blood pressure and blood sugar Hyperlipidemia, once took blood sugar lowering blood pressure lowering multi-medicament, poor effect.In Nikkei hospital detection March 3 in 2011 blood pressure, be 170/110 millimetres of mercury, blood-fat and blood sugar 8.0mmol/L, is diagnosed as three-hypers disease, starts immediately to take the medicine that the embodiment of the present invention 4 provides, and after 1 month, symptom is eliminated.

5, Xu Lijuan, female, 60 years old, suffer from dizziness headache for many years, when tired or excited, aggravation, often accompanies the diseases such as cardiopalmus, insomnia, irritated irritability, soreness of the waist and knees, once takes multiple Western medicine blood pressure lowering, but easily recurrence after drug withdrawal.In July 23 in 2010 Nikkei hospital diagnosis be essential hypertension, blood pressure is 170/105 millimetres of mercury, and the medicine that starts to take the embodiment of the present invention 1 is after 2 months, dizzy, headache disappears substantially, blood pressure drops to 130～90 millimetres of mercury, continue to take medicine 1 month, transference cure, follows up a case by regular visits to and has no recurrence.

6, high mountain peak, man, 51 years old, within 2005, be diagnosed as diabetes, fasting glucose 8.4mmol/L, 2 hours blood glucose 12.3mmol/L after the meal, 2008 there is facial hemiparalysis on the 25th in December, right side hemiplegia, dysphonia, is diagnosed as apoplexy.The medicine that on January 10th, 2009 starts to take the embodiment of the present invention 2 is after 3 months, and speech is clear; Continue to take after 3 months, can walk upright, still adhere at present taking, glycemic control is all right.

7, Yuan Zhijie, man, 63 years old, have a dizzy spell, tinnitus dim eyesight, xerostomia is wish drink not, the tired power of body, right side numb hand and foot, blood pressure is 22.9/13.3kPa after testing, blood viscosity is 6.3, is apoplexy omen.Start to take the medicine 2 months of the embodiment of the present invention 3 on August 15th, 2010, the thick viscosity degradation of blood, it is normal that blood pressure recovers, and continues to take medicine 1 month, and the thick viscosity of blood recovers normal, follows up a case by regular visits to and has no recurrence.

8, Fan Liyun, female, 53 years old, existing 3 years of dizziness headache, with lumbago and skelalgia, upper and lower extremities is numb, and neck pain is gone to a doctor in December in 2007 on the 1st, detecting blood pressure is 180/110 millimetres of mercury, cholesterol 6.7mmol/L, triglyceride is 2.38mmol/L, is diagnosed as hypertension, hyperlipidemia and arteriosclerosis.On February 3rd, 2008 starts to take the medicine of the embodiment of the present invention 4, and after 3 months, blood pressure, blood fat are all down to normal level, follow up a case by regular visits to and have no for many years recurrence.

Claims (6)

1. a medicine for the treatment of three-hypers disease, is characterized in that: it is made by the raw material of following weight portion:

500～1000 parts of Radix Aconiti Lateralis, 500～1000 parts of Fructus Tribulis, 540～1000 parts, Radix Notoginseng, 100～400 parts of Radix Aconiti Lateralis Preparatas, 500～1000 parts of Fructus Crataegis, 250～500 parts of Radix Polygoni Multiflori Preparata, 250～500 parts of Fructus Rosae Laevigatae, 250～500 parts of Herba Apocyni venetis, 180～360 parts of Hirudos, 450～900 parts of Semen Ziziphi Spinosae (parched)s, 300～600 parts of Rhizoma Acori Graminei, 300～600 parts of Rhizoma Chuanxiongs, 900～1000 parts of Caulis Polygoni Multiflori, 450～900 parts of Concha Ostreaes, 300～600 parts of Radix Angelicae Sinensis, 500～1000 parts of Radix Salviae Miltiorrhizaes, 250～500 parts of Concretio silicea Bambusae seu schizostachyi, 250～500 parts of Cortex Lycii, 250～500 parts, sulfur, 500～1000 parts of Radix Ilicis Pubescentiss, 50～100 parts of Herba Asaris, 100～300 parts of Ramulus Cinnamomi, 100～200 parts of Cortex Cinnamomis, 100～200 parts of Rhizoma Zingiberiss,

Its preparation method is as follows:

1) by formula, take each raw material for standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 8～12 times of the weight of feeding intake to boil 1～2h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form fine powder standby;

4) sulfur is ground to form to fine powder standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 1～3 time, the water that at every turn adds 6～20 times of raw material gross weights, each 1～2h that decocts, merge decoction liquor, filter medicinal residues, the extractum that when filtrate is concentrated into 50～70 ℃, relative density is 1.06～1.14, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, make as required different preparations.

2. the medicine for the treatment of three-hypers disease according to claim 1, is characterized in that: the weight portion of each raw material is:

800 parts of Radix Aconiti Lateralis, 700 parts of Fructus Tribulis, 850 parts, Radix Notoginseng, 250 parts of Radix Aconiti Lateralis Preparatas, 700 parts of Fructus Crataegis, 370 parts of Radix Polygoni Multiflori Preparata, 390 parts of Fructus Rosae Laevigatae, 400 parts of Herba Apocyni venetis, 280 parts of Hirudos, 750 parts of Semen Ziziphi Spinosae (parched)s, 450 parts of Rhizoma Acori Graminei, 400 parts of Rhizoma Chuanxiongs, 950 parts of Caulis Polygoni Multiflori, 800 parts of Concha Ostreaes, 500 parts of Radix Angelicae Sinensis, 700 parts of Radix Salviae Miltiorrhizaes, 400 parts of Concretio silicea Bambusae seu schizostachyi, 350 parts of Cortex Lycii, 380 parts, sulfur, 750 parts of Radix Ilicis Pubescentiss, 80 parts of Herba Asaris, 200 parts of Ramulus Cinnamomi, 160 parts of Cortex Cinnamomis, 150 parts of Rhizoma Zingiberiss.

3. the medicine for the treatment of three-hypers disease according to claim 1, its thing is levied and is: the dosage form of described medicine is pill, granule or capsule.

4. the preparation method of the medicine for the treatment of three-hypers disease claimed in claim 1, is characterized in that: comprise the following steps:

1) by formula, take each raw material for standby;

2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed in to container, add the decocting of 8～12 times of the weight of feeding intake to boil 1～2h, filter, get filtrate for later use;

3) Radix Notoginseng and Hirudo are cleaned, dried, grind to form fine powder standby;

4) sulfur is ground to form to fine powder standby;

5) by Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in container, decoct with water 1～3 time, the water that at every turn adds 6～20 times of raw material gross weights, each 1～2h that decocts, merge decoction liquor, filter medicinal residues, the extractum that when filtrate is concentrated into 50～70 ℃, relative density is 1.06～1.14, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mix, make as required different preparations.

5. the preparation method of the medicine for the treatment of three-hypers disease according to claim 4, is characterized in that: granularity 100～300 orders of the fine powder described in step 3) and step 4).

6. the preparation method of the medicine for the treatment of three-hypers disease according to claim 4, is characterized in that: the dosage form of described preparation is pill, granule or capsule.