CN108066588A - A kind of Chinese medicine for treating rhinitis composition, external use plaster and preparation method thereof - Google Patents

A kind of Chinese medicine for treating rhinitis composition, external use plaster and preparation method thereof Download PDF

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CN108066588A
CN108066588A CN201810063482.3A CN201810063482A CN108066588A CN 108066588 A CN108066588 A CN 108066588A CN 201810063482 A CN201810063482 A CN 201810063482A CN 108066588 A CN108066588 A CN 108066588A
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parts
rhinitis
chinese medicine
external use
treatment
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CN108066588B (en
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苗利
刘禹丹
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Henan Zhong Shang Biological Technology Co Ltd
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Henan Zhong Shang Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug

Abstract

The present invention provides a kind of Chinese medicine for treating rhinitis compositions, external use plaster and preparation method thereof, are prepared by the raw material of following parts by weight:0.01 0.06 parts of Chinese blister beetle, 0.03 0.9 parts of Moschus, 3 10 parts of the root of Dahurain angelica, 13 parts of asarum, 39 parts of the achene of Siberian cocklebur, 3 11 parts of tendril-leaved fritillary bulb, 3 10 parts of luffa, 3 12 parts of the tuber of pinellia, the external use plaster include the Chinese medicine composition for the treatment of rhinitis described above.The external use plaster for the treatment rhinitis prepared using raw material proportioning of the present invention and method being capable of expelling wind and clearing away heat, dampness removing is sensible, it is promoting blood circulation and removing blood stasis, by sticking ophryon point, it is permeated using acupuncture point, through lesion, logical nose is had one's ideas straightened out, to acute rhinitis, rhinitis chronic, adenoids, allergic rhinitis, nasosinusitis, the coryzas such as more tears diseases are respectively provided with the effect of good, it is and quick, application method is simple, and three big channels and collaterals of human body can be nursed one's health simultaneously, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, strengthen immunity, oral drug absorption can be overcome slow, the drawbacks of the shortcomings that lesion that cannot go directly and single doctor trained in Western medicine target spot.

Description

A kind of Chinese medicine for treating rhinitis composition, external use plaster and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine for treating rhinitis composition, external use plaster and its Preparation method.
Background technology
Rhinitis is a kind of clinically very common frequently-occurring disease, common disease, is the inflammation of bronchia mucosal and sub-mucosal tissues, It is the inflammation of virus, bacterium, allergen, various physical and chemical factors and bronchia mucosal caused by some systemic diseases.Rhinitis Main pathological change is bronchia mucosal hyperemia, swelling, exudation, hyperplasia, atrophy or necrosis etc..Patient has nasal obstruction, more tears, smell more The symptoms such as decline, headache, giddy, failure of memory, snoring, fatiguability, often cause pharyngitis, laryngitis, tracheitis and tympanitis Etc. complication, it is obstinate and be not easy to cure.
Rhinitis can be divided into the several types such as acute, chronic, atrophic, allergy, caseous, hypertrophica.Modern times doctor Often take intranasal glucocorticoid administration, irrigation of nasal cavity, antihistamine drug, vasoconstrictor and some Chinese patent drugs pair Patients with rhinitis is treated, and takes operative treatment for serious patient, but effect is less apparent, is not easy to cure and easily stay Lower side effect forms rhinitis medicamentosa or schneiderian membrance is caused to damage or even formed " Empty nose syndromes ", bigger is caused to patient Pain.
And from the Chinese point of view, the rhinitis traditional Chinese medical science belongs to nasosinusitis scope, in ancient literature,《Interior warp》Address this disease earliest. Traditional Chinese medicine has apparent advantage in acute and chronic rhinitis is treated, and by dialectical treatmert, forms multiple therapy methods, such as:
1st, lung channel heat evil, a surname's clearing lung-heat are sensible:Nose be lung outside key, heat evil accumulate product in lung, Chang Shangzhuo noses key and be tears be deep pool.《Element It asks to very discussing greatly》In " few cloudy answers, and makees ... very then to enter lung in regretful heat, cough and nasosinusitis " indicate that lung heat smokes bright sinus key Into nasosinusitis, Yinqiao San plus-minus can be closed with Cang'erzi San.
2nd, flaring up of stomach fire, it is bright that weight rushes down clearly sun:Urgency person's multi-source of nasosinusitis is divided into lung, courage, stomach energy in burning hot.The bright stomach energy of sun The sinus key that burns is steamed into nasosinusitis, and the yellow turbid amount of partially visible tears is more, and very, smell is poor, and concha swelling, mucous membrane is dark red and dry for nasal obstruction, headache Substantially, nasal sinus corresponding site is kowtowed, tenderness or redness, whole body are urinated often with fever, thirst and drinking, halitosis, gum redness, constipation Red to wait diseases, common drug is cimicifugae foetidae 10g, pueraria lobata 15g, RADIX PAEONIAE RUBRA 12g, radix scutellariae 12g, cordate houttuynia 12g, dandelion 20g, campanulaceae 10g, root of Dahurain angelica 10g, spina gleditsiae 10g, achene of Siberian cocklebur 10g, Radix Glycyrrhizae 6g.
Although more than therapy has the effect of certain in treatment rhinitis, exist must it is dialectical clearly, prescription flavour of a drug are more, use Medicine is smart, it is fried it is cumbersome, oral cannot go directly lesion the shortcomings of.
In the prior art, CN102451238B discloses a kind of Chinese medicine for treating rhinitis composition, which includes:Punching Lotus, giant knotweed, Pogostemon cablin, the flower bud of lily magnolia, radix scutellariae, Chinese ephedra etc. have the effect of clear scorching heat-clearing, expelling wind and clearing away cold, sensible analgesic; CN105597036A discloses a kind of external-use extract for treating rhinitis, which includes the medicines such as the flower bud of lily magnolia, curcuma zedoary, the root of Dahurain angelica, Jiang Muhua Object possesses awakening consciousness, promoting qi circulation and removing obstruction in the collateral effect, more than formula have the effect of certain to the treatment of rhinitis, but have ignored benefit The principle that beneficial lung qi, warm kidney warm up spleen, strengthen the body resistance to consolidate the constitution, late result is not good enough, easy recurrent exerbation.
The content of the invention
It is an object of the invention to overcome deficiency of the prior art, a kind of Chinese medicine for treating rhinitis composition, outer is provided With patch and preparation method thereof.
To achieve these goals, the technical solution adopted by the present invention is as follows:
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.01-0.06 parts of Chinese blister beetle, Moschus 0.03-0.9 parts, 3-10 parts of the root of Dahurain angelica, 1-3 parts of asarum, 3-9 parts of the achene of Siberian cocklebur, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of luffa, tuber of pinellia 3-12 Part.
The Chinese medicine composition of above-mentioned treatment rhinitis, wherein, it is prepared by the raw material of following parts by weight:Chinese blister beetle 0.035 Part, 0.46 part of Moschus, 6.5 parts of the root of Dahurain angelica, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia.
A kind of external use plaster for treating rhinitis includes the Chinese traditional medicine composition of any treatment rhinitis of claim 1-2 Object.
The preparation method of the external use plaster of above-mentioned treatment rhinitis, includes the following steps:
(1)The raw material of the Chinese medicine composition of above-mentioned parts by weight treatment rhinitis is weighed, after drying, 250- is processed by broken wall ultra micro 350 targeted fine powders are uniformly mixed to get the Chinese medicine composition of the present invention;
(2)The medical pressure-sensing thermosol for weighing 90-110g is put into heating and melting in pot, treats that temperature is cooled to 72-78 DEG C, by step (1)In Chinese medicine composition obtained add in and stir evenly slowly, treat that temperature is cooled to 52-58 DEG C, add in azone 4-6mL, borneol With each 2.5-3.5g of camphor, continue to stir into cream;
(3)By step(2)Cream beach obtained on non-woven fabrics, cover release paper, section, pack to get.
In the formula of the Chinese medicine composition of present invention treatment rhinitis, Chinese blister beetle, acrid flavour, property heat, toxic Return liver, stomach, kidney channel, tool Have blood-breaking by become silted up, dissipating bind disappear lump in the abdomen, attack the effect of malicious phagedenoma;Moschus, warm-natured, nontoxic, bitter, the thoughts of returning home, the spleen channel have and have one's ideas straightened out, ward off Dirty, dredging collateral dissipates the effect of stasis of blood;The root of Dahurain angelica, warm-natured, acrid flavour, return lung, spleen, stomach, have relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, clearing the nasal passage, The effect of eliminating dampness stops band, detumescence and apocenosis;Asarum, warm-natured, acrid flavour, return lung, kidney channel have expelling wind and clearing away cold, sensible analgesic, warm lung The effect of drink;The achene of Siberian cocklebur, warm-natured, sweet in flavor, return lung, Liver Channel have the effect of expelling wind and clearing away cold, sensible analgesic;Tendril-leaved fritillary bulb, cool in nature, taste It is sweet, it attaches to the lung and stomach meridians, there is moistening lung, cough-relieving, resolving sputum;Luffa, cool in nature, sweet in flavor, return lung, stomach, Liver Channel have promoting menstruation The effect of active, removing toxicity for detumescence;The tuber of pinellia, warm-natured, acrid flavour, returns spleen, stomach have eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the raw furuncle that disappears The effect of.
From the Chinese point of view, rhinitis is mostly because of visceral dysfunction, and along with catching cold, perverse trend is attacked nose key and caused. This disease is often touching refractory, is first weakened body resistance and evil love, is second that exopathogen is objective long, changes the bright Tianjin of fire and the turbid obstruction nose key of phlegm.Therefore, Vital organs of the human body functional disturbance for this, mainly including lung, spleen, kidney it is deficient.Spleen pertaining to the earth, is the mother of lung, the source of students of spleen deficiency then lung The deficiency syndrome of the lung absolutely;Kidney category water, Jinsui River alternate, and lung receive gas and are attributed to kidney, and the two interacts.Therefore, treatment rhinitis first needs to effect a permanent cure, weight Point is that replenishing and restoring lung qi, warm kidney warm up spleen, strengthen the body resistance to consolidate the constitution.In the formula of the present invention, the root of Dahurain angelica, asarum, the achene of Siberian cocklebur, tendril-leaved fritillary bulb, luffa Can replenishing and restoring lung qi, facilitaing lung it is sensible, Chinese blister beetle, Moschus, the root of Dahurain angelica, asarum, the tuber of pinellia can warm kidney warm up spleen, all medicine compatibilities being capable of wind-dispelling Heat-clearing, dampness removing are sensible, promoting blood circulation and removing blood stasis, by sticking ophryon point, are permeated using acupuncture point, and lesion of going directly, logical nose is had one's ideas straightened out, to acute nose The coryzas such as inflammation, rhinitis chronic, adenoids, allergic rhinitis, nasosinusitis, more tears diseases are respectively provided with the effect of good, and Quick, short treating period, application method is simple, easy to carry, and can nurse one's health three big channels and collaterals of human body simultaneously, and Yin Yang balancing, righting is dispelled Heresy, strengthen immunity can overcome oral drug absorption slow, it is impossible to the shortcomings that through lesion and the drawbacks of doctor trained in Western medicine target spot is single.
Chinese medicine composition of the present invention, details are as follows in 2011 to 2015 clinical treatment situations for externally used paste:
1st, patient profile:Select the projects such as medical history, the state of an illness, age, gender and original therapy method.
2nd, patient source:With general hospital patient and special chinic patient in hospital.
3rd, case inclusion criteria:Clinical manifestation and pathological characters according to patients with rhinitis point, and gender, age are unlimited, row Except gestation and nursing period patient, various other drugs and therapeutic modality for treating rhinitis are disabled before treatment.
4th, therapy
Prescription:0.035 part of Chinese blister beetle, 0.46 part of Moschus, 6.5 parts of the root of Dahurain angelica, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, luffa 6.5 Part, 7.5 parts of the tuber of pinellia;
Preparation method:(1)After the raw material stoving for weighing above-mentioned parts by weight treatment rhinitis Chinese medicine composition, surpass by wall-breaking machine broken wall Micro mist is broken into 300 targeted fine powders and uniformly mixes to get Chinese medicine composition;
(2)Medical pressure-sensing hot melt adhesive 100g is taken, is put into slow boiling heating and melting in stainless-steel pan;
(3)Treat that temperature is cooled to 75 DEG C, by step(1)In Chinese medicine composition obtained slowly add in stir evenly;
(4)When temperature is cooled to 55 DEG C, addition azone 5mL, borneol and each 3g of camphor, uniform stirring can beach into cream
(5)By ointment beach on non-woven fabrics, release paper is covered, section is often pasted weight 1.8g-2.0g, packed to get external patch Agent;
Application method:External use plaster is pasted on the ophryon point between two eyebrows, when often patch 10 is small, is pasted within 10 days one, 3 patches are treated for one Journey.
5th, efficacy evaluation
Recovery from illness:Rhinitis Symptoms disappear, without recurrence in follow-up 2 years;
Significantly:Rhinitis Symptoms substantially slow down;
Effectively:Rhinitis Symptoms are slowed down;
It is invalid:Variation is little before and after treatment.
6th, efficacy analysis
Gender:According to inclusion criteria, patients with rhinitis 258, wherein acute rhinitis patient 45, rhinitis chronic patient 50 are treated altogether Example;Adenoids patient 41, Allergic Rhinitis 69, sinusitis in patients 53;
The course of disease:- 5 months 1 month are 75, and -2 years 6 months are 85, and 2 years or more are 45, and 5 years or more are 39.7 years with Upper is 14
Age group:4-20 Sui is 108, and 20-30 Sui is 97, and 31 years old or more is 53;
Disease type is shown in Table 1 with curative effect, and administration time is two courses for the treatment of.
From table 1 it follows that use it is provided by the invention treatment rhinitis Traditional Chinese medicine external patch for acute rhinitis, The diseases such as rhinitis chronic, adenoids, allergic rhinitis, nasosinusitis have it is notable the effect of, cure rate 87%, notable 10%, It is effectively 3%, total effective rate has reached 100%, and uneasy to recur.
Specific embodiment
Embodiment 1
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.01-0.06 parts of Chinese blister beetle, musk deer 0.03-0.9 parts fragrant, 3-10 parts of the root of Dahurain angelica, 1-3 parts of asarum, 3-9 parts of the achene of Siberian cocklebur, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of luffa, tuber of pinellia 3- 12 parts;
A kind of external use plaster for treating rhinitis includes the Chinese medicine composition of above-mentioned treatment rhinitis;
The preparation method of the external use plaster of above-mentioned treatment rhinitis, includes the following steps:
(1)After the raw material stoving for weighing above-mentioned parts by weight treatment rhinitis Chinese medicine composition, by wall-breaking machine broken wall ultramicro grinding into 250-350 targeted fine powders are uniformly mixed to get Chinese medicine composition;
(2)Medical pressure-sensing hot melt adhesive 90-110g is taken, is put into slow boiling heating and melting in stainless-steel pan;
(3)Treat that temperature is cooled to 72-78 DEG C, by step(1)In Chinese medicine composition obtained slowly add in stir evenly;
(4)When temperature is cooled to 52-58 DEG C, azone 4-6mL, borneol and each 2.5-3.5g of camphor are added in, uniform stirring is into cream It can beach;
(5)By ointment beach on non-woven fabrics, release paper is covered, section is often pasted weight 1.8g-2.0g, packed to get external patch Agent;
The external use plaster for the treatment of rhinitis prepared using above-mentioned raw materials proportioning and method can expelling wind and clearing away heat, dampness removing be sensible, work Blood stagnation resolvation by sticking ophryon point, is permeated using acupuncture point, and lesion of going directly, logical nose is had one's ideas straightened out, to acute rhinitis, rhinitis chronic, adenoid Body is loose, allergic rhinitis, nasosinusitis, and the coryzas such as more tears diseases are respectively provided with the effect of good, and quick, and short treating period makes It is simple with method, it is easy to carry, and three big channels and collaterals of human body, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, strengthen immunity, energy can be nursed one's health simultaneously Enough overcome oral drug absorption slow, it is impossible to the shortcomings that through lesion and the drawbacks of doctor trained in Western medicine target spot is single.
Embodiment 2
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.035 part of Chinese blister beetle, Moschus 0.46 part, 6.5 parts of the root of Dahurain angelica, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia;
A kind of external use plaster for treating rhinitis includes the Chinese medicine composition of above-mentioned treatment rhinitis;
The preparation method of the external use plaster of above-mentioned treatment rhinitis, includes the following steps:
(1)After the raw material stoving for weighing above-mentioned parts by weight treatment rhinitis Chinese medicine composition, by wall-breaking machine broken wall ultramicro grinding into 300 targeted fine powders are uniformly mixed to get Chinese medicine composition;
(2)Medical pressure-sensing hot melt adhesive 100g is taken, is put into slow boiling heating and melting in stainless-steel pan;
(3)Treat that temperature is cooled to 75 DEG C, by step(1)In Chinese medicine composition obtained slowly add in stir evenly;
(4)When temperature is cooled to 55 DEG C, addition azone 5mL, borneol and each 3g of camphor, uniform stirring can beach into cream;
(5)By ointment beach on non-woven fabrics, release paper is covered, section is often pasted weight 1.8g-2.0g, packed to get external patch Agent;
The external use plaster for the treatment of rhinitis prepared using above-mentioned raw materials proportioning and method can expelling wind and clearing away heat, dampness removing be sensible, work Blood stagnation resolvation by sticking ophryon point, is permeated using acupuncture point, and lesion of going directly, logical nose is had one's ideas straightened out, to acute rhinitis, rhinitis chronic, adenoid Body is loose, allergic rhinitis, nasosinusitis, and the coryzas such as more tears diseases are respectively provided with the effect of good, and quick, and short treating period makes It is simple with method, it is easy to carry, and three big channels and collaterals of human body, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, strengthen immunity, energy can be nursed one's health simultaneously Enough overcome oral drug absorption slow, it is impossible to the shortcomings that through lesion and the drawbacks of doctor trained in Western medicine target spot is single.
Embodiment 3
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.01-0.06 parts of Chinese blister beetle, musk deer 0.03-0.9 parts fragrant, 3-10 parts of the root of Dahurain angelica, 1-3 parts of asarum, 3-9 parts of the achene of Siberian cocklebur, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of luffa, tuber of pinellia 3- 12 parts;
A kind of external use plaster for treating rhinitis includes the Chinese medicine composition of above-mentioned treatment rhinitis;
The preparation method of the external use plaster of above-mentioned treatment rhinitis, includes the following steps:
(1)The above-mentioned parts by weight achene of Siberian cocklebur, luffa, the tuber of pinellia, asarum are taken, adding in volume ratio is(1:5)-(1:3)Water impregnate it is 1 small Shi Hou, heating decoct 2 times, boil subsequently pan-fried 20-30min every time, and the liquid decocted twice is stood 24-36h by leaching liquid, Leaching supernatant concentration hangs flag or spare with ripple Mei Shi specific density tables survey relative density 1.1 ~ 1.20 (70-80 DEG C) to medicinal extract shape;
(2)After the Chinese blister beetle of above-mentioned weight, the root of Dahurain angelica, tendril-leaved fritillary bulb, Moschus drying, co-grinding is placed on close into 250-350 targeted fine powders Close containers for future use;
(3)The Malaysia glue of 3.5-4 times of above-mentioned raw materials total weight parts is taken, is melted with slow boiling, when temperature is cooled to 68-72 DEG C, It is stirred continuously down and is slowly added into step(1)Medicinal extract obtained after stirring, continues to heat to remove aqueous vapor with slow boiling, 48-52 DEG C is cooled to, adds in step(2)Fine powder obtained, stirs into cream;
(4)By step(3)Cream beach obtained covers release paper on non-woven fabrics, and section is often pasted weight 1.8g-2.0g, packed, Up to external use plaster;
The external use plaster for the treatment of rhinitis prepared using above-mentioned raw materials proportioning and method can expelling wind and clearing away heat, dampness removing be sensible, work Blood stagnation resolvation by sticking ophryon point, is permeated using acupuncture point, and lesion of going directly, logical nose is had one's ideas straightened out, to acute rhinitis, rhinitis chronic, adenoid Body is loose, allergic rhinitis, nasosinusitis, and the coryzas such as more tears diseases are respectively provided with the effect of good, and quick, and short treating period makes It is simple with method, it is easy to carry, and three big channels and collaterals of human body, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, strengthen immunity, energy can be nursed one's health simultaneously Enough overcome oral drug absorption slow, it is impossible to the shortcomings that through lesion and the drawbacks of doctor trained in Western medicine target spot is single.
Embodiment 4
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.01-0.06 parts of Chinese blister beetle, musk deer 0.03-0.9 parts fragrant, 3-10 parts of the root of Dahurain angelica, 1-3 parts of asarum, 3-9 parts of the achene of Siberian cocklebur, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of luffa, tuber of pinellia 3- 12 parts;
A kind of external use plaster for treating rhinitis includes the Chinese medicine composition of above-mentioned treatment rhinitis;
The preparation method of the external use plaster of above-mentioned treatment rhinitis, includes the following steps:
(1)After the Chinese medicine of above-mentioned parts by weight is dried, co-grinding is placed on spare in closed container into 100-200 mesh fine powders;
(2)By step(1)Traditional Chinese drug mixture obtained is soaked with 70% alcohol steep solution, closed placement 0.5-5h, with fine powder Subject to full and uniform wetting and expansion;
(3)By the loading diacolation of the medicaments uniformity of wetting, 24-48h is impregnated, slowly diacolation, collect percolate, be concentrated into relatively close Spend the medicinal extract for 1.1-1.3;
(4)By step(3)Medicinal extract obtained is blended into 11-13g rubber paste matrix, and beach covers release paper, cut on non-woven fabrics Piece often pastes weight 1.8g-2.0g, packs to get external use plaster;
The external use plaster for the treatment of rhinitis prepared using above-mentioned raw materials proportioning and method can expelling wind and clearing away heat, dampness removing be sensible, work Blood stagnation resolvation by sticking ophryon point, is permeated using acupuncture point, and lesion of going directly, logical nose is had one's ideas straightened out, to acute rhinitis, rhinitis chronic, adenoid Body is loose, allergic rhinitis, nasosinusitis, and the coryzas such as more tears diseases are respectively provided with the effect of good, and quick, and short treating period makes It is simple with method, it is easy to carry, and three big channels and collaterals of human body, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, strengthen immunity, energy can be nursed one's health simultaneously Enough overcome oral drug absorption slow, it is impossible to the shortcomings that through lesion and the drawbacks of doctor trained in Western medicine target spot is single.
Comparative example 1
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.035 part of Chinese blister beetle, the root of Dahurain angelica 6.5 Part, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia;A kind of external use plaster for treating rhinitis, bag Chinese medicine composition containing above-mentioned treatment rhinitis;Specific preparation method compared with Example 2, is not added with musk deer with embodiment 2 Perfume (or spice), the external use plaster patient prepared is not good enough using curative effect, recovers slower.
Comparative example 2
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.46 part of Moschus, the root of Dahurain angelica 6.5 Part, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia;A kind of external use plaster for treating rhinitis, bag Chinese medicine composition containing above-mentioned treatment rhinitis;Specific preparation method compared with Example 2, dispels Chinese blister beetle with embodiment 2, The external use plaster patient prepared stick effect it is micro-, nasal obstruction and headache syndromes without alleviation.
Comparative example 3
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.035 part of Chinese blister beetle, Moschus 0.46 part, 2.8 parts of the root of Dahurain angelica, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 13 parts of the tuber of pinellia;It is a kind of to treat rhinitis External use plaster, include the Chinese medicine composition of above-mentioned treatment rhinitis;Specific preparation method is with embodiment 2, with 2 phase of embodiment Than the dosage of the root of Dahurain angelica being reduced to 2.8 parts from 6.5 parts, the tuber of pinellia increases to 13 parts, under the external use plaster prepared is with obvious effects Drop, malaise symptoms are alleviated slower.
Comparative example 4
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.035 part of Chinese blister beetle, Moschus 0.46 part, 6.5 parts of the root of Dahurain angelica, 0.8 part of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 11 parts of luffa, 7.5 parts of the tuber of pinellia;It is a kind of to treat nose Scorching external use plaster includes the Chinese medicine composition of above-mentioned treatment rhinitis;Specific preparation method is with embodiment 2, with embodiment 2 It compares, the dosage of asarum is reduced to 0.8 part from 2 parts, the amount of luffa increases to 11 parts from 6.5 parts, the external use plaster prepared Patient adds two courses for the treatment of after.
Comparative example 5
A kind of Chinese medicine for treating rhinitis composition is prepared by the raw material of following parts by weight:0.008 part of Chinese blister beetle, Moschus 0.03 part, 6.5 parts of the root of Dahurain angelica, 2 parts of asarum, 2 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia;It is a kind of to treat rhinitis External use plaster, include the Chinese medicine composition of above-mentioned treatment rhinitis;Specific preparation method is with embodiment 2, with 2 phase of embodiment Than the dosage of Chinese blister beetle being reduced to 0.008 part from 0.035, the dosage of Moschus reduces to 0.03 part from 0.46, and the dosage of the achene of Siberian cocklebur is from 6 Part reduces to 2 parts, and the external use plaster patient prepared is not relieved using rear nasal obstruction, sneezing symptom, and nasal membrane oedema disappears It loses slower.
The formula for a kind of Chinese medicine for treating rhinitis composition that 3-25 of the embodiment of the present invention is provided is shown in Table 2-4.
Model case
Case one:Mr. Lin, man, 29 years old, rhinitis chronic 22 years, with nasal obstruction, headache, unsmooth breath can only be breathed, readme with face Because nose breathing cannot be used for a long time, causing failure of memory, facial deformation, bridge of the nose lateral bending is dashed forward before face, through multi-treatment, Effect unobvious, pain are abnormal;The external use plaster prepared using the embodiment of the present invention 2 is treated, and is affixed on before sleeping at night Ophryon point, the next morning think that nose is unobstructed, and all symptoms mitigate, using a course for the treatment of, recovery from illness, follow-up 2 years, without multiple Hair.
Case two:Zhang, female, 15 years old, nasosinusitis was often had a headache, and hyposmia is prepared using the embodiment of the present invention 2 External use plaster be affixed on ophryon point, nose can smell taste after 3 days, and headache mitigates, and continues to make a course for the treatment of, fully recover, follow-up two Year, no recurrence.
Case three:Mr. Wang, male, 45 years old, allergic rhinitis 25 years, loose with deviation of nasal septum, concha, spring and autumn was easily sent out Make, air aggravates to the cold, and when breaking-out is serious, has a running nose, drops tears, sneezes, unsmooth breath, and when nighttime sleep snores, and uses The external use plaster that the embodiment of the present invention 2 is prepared is affixed on ophryon point, and symptom mitigates after a patch, fully recovers after a course for the treatment of, follow-up two Year is without recurrence.
Case four:Liang, 8 years old, adenoids, ventilation was not smooth, and nighttime sleep opens one's mouth to breathe, with snoring, in locals ENT dept. of people hospital checks, informs that household needs operative treatment, because the age is still small, family members are reluctant to perform the operation.Implemented using the present invention The external use plaster that example 2 is prepared is affixed on ophryon point, and a patch mitigates, and 5 patch recoveries from illness, follow-up is not recurred for 3 years.
Case five:Feng, because flu causes acute sinusitis, yellow purulence tears are flowed in headache, and local Transfusion For Outpatients have no for 3 days to be subtracted Gently, the external use plaster prepared using the embodiment of the present invention 2 is affixed on ophryon point, once fully recovers, and follow-up is not recurred for 2 years.

Claims (4)

1. a kind of Chinese medicine for treating rhinitis composition, which is characterized in that be prepared by the raw material of following parts by weight:Chinese blister beetle 0.01-0.06 parts, 0.03-0.9 parts of Moschus, 3-10 parts of the root of Dahurain angelica, 1-3 parts of asarum, 3-9 parts of the achene of Siberian cocklebur, 3-11 parts of tendril-leaved fritillary bulb, luffa 3-10 parts, 3-12 parts of the tuber of pinellia.
2. the Chinese medicine composition for the treatment of rhinitis as described in claim 1, which is characterized in that prepared by the raw material of following parts by weight It forms:0.035 part of Chinese blister beetle, 0.46 part of Moschus, 6.5 parts of the root of Dahurain angelica, 2 parts of asarum, 6 parts of the achene of Siberian cocklebur, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of luffa, 7.5 parts of the tuber of pinellia.
3. a kind of external use plaster for treating rhinitis, which is characterized in that include any treatment rhinitis of claim 1-2 Chinese medicine composition.
4. the preparation method of the external use plaster for the treatment of rhinitis as claimed in claim 3, which is characterized in that include the following steps:
(1)The raw material of the Chinese medicine composition of above-mentioned parts by weight treatment rhinitis is weighed, after drying, 250- is processed by broken wall ultra micro 350 targeted fine powders are uniformly mixed to get the Chinese medicine composition of the present invention;
(2)The medical pressure-sensing thermosol for weighing 90-110g is put into heating and melting in pot, treats that temperature is cooled to 72-78 DEG C, by step (1)In Chinese medicine composition obtained add in and stir evenly slowly, treat that temperature is cooled to 52-58 DEG C, add in azone 4-6mL, borneol With each 2.5-3.5g of camphor, continue to stir into cream;
(3)By step(2)Cream beach obtained on non-woven fabrics, cover release paper, section, pack to get.
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Publication number Priority date Publication date Assignee Title
CN113730498A (en) * 2020-05-27 2021-12-03 北京圣手苗医堂企业管理有限公司 Rhinitis traditional Chinese medicine patch and preparation method thereof
CN113730498B (en) * 2020-05-27 2022-05-24 北京圣手苗医堂企业管理有限公司 Rhinitis traditional Chinese medicine patch and preparation method thereof

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