CN108066588B - Traditional Chinese medicine composition for treating rhinitis, external patch and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating rhinitis, external patch and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating rhinitis, an external patch and a preparation method thereof, wherein the external patch is prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of bulbus fritilariae, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate, and the external patch comprises the traditional Chinese medicine composition for treating rhinitis. The external patch for treating rhinitis, which is prepared by adopting the raw material proportion and the method, can expel wind and clear heat, remove dampness and dredge orifices, activate blood and remove blood stasis, directly reach the focus by applying to Yintang acupoint, and achieve the effects of dredging nose and inducing resuscitation by utilizing acupoint permeation, has good curative effects on rhinitis diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis, nasosinusitis, rhinorrhea and the like, is quick in response and simple in use method, can simultaneously condition three main and collateral channels of a human body, balance yin and yang, strengthen body resistance and eliminate pathogenic factors, enhances the immunity, and can overcome the defects that oral medicines are slow in absorption and cannot directly reach the focus and the defect that western medicine has a single target spot.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating rhinitis, an external patch and a preparation method thereof.
Background
Rhinitis is a frequently encountered disease and a common disease clinically, is inflammation of nasal mucosa and submucosal tissues, and is inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physicochemical factors and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of the nasal mucosa. Patients often have symptoms of nasal obstruction, nasal discharge, sense of smell decline, headache, dizziness, hypomnesis, snoring, easy fatigue and the like, and the complications of pharyngitis, laryngitis, tracheitis, otitis media and the like are often caused and are stubborn and difficult to cure.
Rhinitis can be classified into acute, chronic, atrophic, allergic, caseous, hypertrophic and other types. Modern medicine usually adopts intranasal glucocorticoid to administer, nasal cavity washing method, antihistamine, vasoconstrictor and some Chinese patent medicines to treat rhinitis patients, adopts operation treatment for serious patients, but the effect is not obvious, the treatment is not easy, side effects are easy to remain, drug rhinitis is formed or nasal mucosa damage is caused, even 'empty nose syndrome' is formed, and more pain is caused to the patients.
From the perspective of traditional Chinese medicine, rhinitis in traditional Chinese medicine belongs to the nasosinusitis category, and the disease is first mentioned in the 'Nei Jing' in ancient documents. The traditional Chinese medicine has obvious advantages in treating acute and chronic rhinitis, and forms various treatment methods through dialectical treatment, such as:
1. lung meridian heat pathogen, dispersing lung heat and promoting resuscitation: nose is the orifice outside the lung, and heat pathogen accumulates in the lung and burns the orifice and nasal discharge is the sinusitis. In Su Wen, Zhi Zhen Yao Da Lun, "the recovery of shaoyin, chai Yin, the inner work of chai Yin, even though entering the lung and cough with nasosinusitis" indicates that the lung heat fumigates the sinus orifice to form nasosinusitis, which can be modified by cang Er Zi powder and Yinqi powder.
2. Ascending of stomach fire, heavy diarrhea and yangming: the urgent nasal sinusitis is caused by fire heat, which is classified into lung heat, gallbladder heat and stomach heat. Yangming stomach heat evaporates and burns the sinus orifice to form nasosinusitis, the local part can show more yellow and turbid nasal discharge, nasal obstruction, bad smell, swollen nasal concha, deep red and dry mucous membrane, obvious headache, percussion, tenderness or red swelling of the corresponding part of the nasal sinus, fever, thirst, halitosis, red swelling of gum, constipation, dark urine and other symptoms, and the common medicines comprise 10g of largetrifoliolioliolious bugbane rhizome, 15g of kudzuvine root, 12g of red peony root, 12g of baical skullcap root, 12g of heartleaf houttuynia herb, 20g of dandelion, 10g of platycodon grandiflorum, 10g of dahurian angelica root, 10g of Chinese honeylocust spine, 10g of siberian cocklebur fruit and.
The above treatment methods have certain curative effects on rhinitis, but have the defects of clear dialectical evidence, more medicinal ingredients, incomprehensive medication, complicated decoction, incapability of directly reaching focus of infection by oral administration and the like.
In the prior art, CN102451238B discloses a traditional Chinese medicine composition for treating rhinitis, which comprises the following components: herba Andrographitis, rhizoma Polygoni Cuspidati, herba Agastaches, flos Magnoliae, Scutellariae radix, herba Ephedrae, etc., and has effects of clearing away heat and toxic materials, dispelling pathogenic wind, dispelling cold, inducing resuscitation, and relieving pain; CN105597036A discloses an external use extract for treating rhinitis, the formula comprises magnolia flower, zedoary, angelica dahurica, curcuma alismatifolia and other medicaments, the extract has the efficacies of aromatic resuscitation, qi circulation and collateral obstruction, the above formula has certain curative effect on the treatment of rhinitis, but neglects the principles of lung qi tonifying, kidney warming, spleen warming, body resistance strengthening and body resistance strengthening, the long-term curative effect is not good enough, and the extract is easy to relapse.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provides a traditional Chinese medicine composition for treating rhinitis, an external patch and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
a traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate.
The traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 0.46 parts of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate.
A patch for external use for treating rhinitis, comprising the Chinese medicinal composition for treating rhinitis according to any one of claims 1 to 2.
The preparation method of the external patch for treating rhinitis comprises the following steps:
(1) weighing the raw materials of the traditional Chinese medicine composition for treating rhinitis in parts by weight, drying, performing wall breaking ultramicro treatment to obtain fine powder of 250-350 meshes, and uniformly mixing to obtain the traditional Chinese medicine composition;
(2) weighing 90-110g of medical pressure-sensitive thermosol, putting into a pot, heating to melt, cooling to 72-78 ℃, slowly adding the traditional Chinese medicine composition prepared in the step (1), uniformly stirring, cooling to 52-58 ℃, adding 4-6mL of azone, 2.5-3.5g of borneol and camphor respectively, and continuously stirring to form paste;
(3) and (3) coating the paste prepared in the step (2) on non-woven fabric, covering release paper, slicing and packaging to obtain the adhesive plaster.
In the formula of the traditional Chinese medicine composition for treating rhinitis, cantharis is pungent in taste, hot in nature and toxic in liver, stomach and kidney meridians, and has the effects of breaking blood and removing stasis, dissipating stagnation and eliminating abdominal mass, and attacking toxin and corroding sores; musk is warm in nature, non-toxic and bitter in taste, has the effects of tonifying heart and spleen channels, and has the effects of inducing resuscitation, removing dirt, dredging collaterals and dissipating blood stasis; the angelica dahurica is warm in nature and pungent in taste, enters lung, spleen and stomach channels, and has the effects of relieving exterior syndrome, dispelling cold, dispelling wind, relieving pain, dredging nasal orifices, eliminating dampness, stopping leukorrhagia, reducing swelling and expelling pus; the asarum herb is warm in nature and pungent in taste, enters lung and kidney channels, and has the effects of expelling wind and clearing away cold, dredging orifices and relieving pain, and warming lung and resolving fluid retention; fructus xanthil is warm in nature and sweet in taste, enters lung and liver channels, and has the effects of dispelling wind and cold, and relieving stuffiness and pain; bulbus Fritillariae Cirrhosae, cool in nature, sweet in taste, and entering lung and stomach meridians, has effects of moistening lung, relieving cough, and eliminating phlegm; the loofah sponge is cool in nature and sweet in taste, enters lung, stomach and liver channels, and has the effects of clearing and activating the channels and collaterals, and detoxifying and reducing swelling; ban Xia, warm in nature and pungent in flavor, enters spleen and stomach meridians, and has the actions of drying dampness and resolving phlegm, checking adverse rise of qi and relieving vomiting, and relieving furuncle and swelling for unprocessed use.
From the perspective of traditional Chinese medicine, rhinitis is mostly caused by dysfunction of the zang-fu organs, and invasion of pathogenic qi into nasal orifices due to affection of exogenous wind-cold. The disease is usually lingering and difficult to cure, namely, the body resistance is weak and the pathogenic factors linger, and the exogenous pathogenic factors are long-term and lead to fire, fluid burning and phlegm turbidity obstruction of nasal orifices. Therefore, the dysfunction of the five zang-organs and six fu-organs is the cause and mainly includes the deficiency of the lung, spleen and kidney. Spleen pertains to earth and is the mother of lung, and spleen deficiency can cause the generation and transformation of lung and lung deficiency; kidneys belong to water, gold water grows mutually, and lung qi reception is ascribed to kidneys, and the two affect each other. Therefore, treating rhinitis requires treating the root cause first, and the key points are tonifying lung qi, warming kidney and spleen, and strengthening body resistance to consolidate the constitution. In the formula of the traditional Chinese medicine composition, the angelica dahurica, the asarum, the siberian cocklebur fruit, the bulbus fritillariae cirrhosae and the loofah sponge can tonify lung qi, ventilate lung and dredge orifices, the cantharis, the musk, the angelica dahurica, the asarum and the pinellia ternate can warm the kidney and the spleen, the compatibility of the medicines can dispel wind and clear heat, remove dampness and dredge orifices, and promote blood circulation to remove blood stasis.
The clinical treatment conditions of the traditional Chinese medicine composition and the external ointment in 2011 to 2015 are detailed as follows:
1. patient profile: selecting the items of medical history, disease condition, age, sex and original treatment method.
2. The source of the patient is as follows: to integrate hospital patients and professional outpatient hospital patients.
3. Case inclusion criteria: according to the clinical manifestations and pathological characteristics of rhinitis patients, but sex and age are not limited, patients in pregnancy and lactation are excluded, and various other medicines and treatment modes for treating rhinitis are stopped before treatment.
4. Method of treatment
Prescription: 0.035 parts of cantharis, 0.46 parts of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate;
the preparation method comprises the following steps: (1) weighing the raw materials of the traditional Chinese medicine composition for treating rhinitis in parts by weight, drying, breaking the wall by a wall breaking machine, micronizing into fine powder of 300 meshes, and uniformly mixing to obtain the traditional Chinese medicine composition;
(2) taking 100g of medical pressure-sensitive hot melt adhesive, and putting the medical pressure-sensitive hot melt adhesive into a stainless steel pot to be heated and melted by mild fire;
(3) slowly adding the traditional Chinese medicine composition prepared in the step (1) into the mixture and stirring the mixture evenly when the temperature is cooled to 75 ℃;
(4) when the temperature is cooled to 55 ℃, 5mL of azone, 3g of borneol and camphor are added respectively, and the mixture is evenly stirred into paste, thus obtaining the mud flat
(5) Spreading the ointment on non-woven fabric, covering release paper, slicing, and packaging to obtain topical patch, wherein the weight of each patch is 1.8-2.0 g;
the using method comprises the following steps: the external patch is applied to Yintang acupoint between two eyebrows, 10 hours per patch, 10 days per patch, and 3 patches as a treatment course.
5. Assessment of efficacy
And (3) healing: the rhinitis symptom disappears, and no relapse occurs within 2 years of follow-up;
remarkably: the rhinitis symptom is obviously relieved;
the method has the following advantages: the rhinitis symptom is relieved;
and (4) invalidation: the change before and after treatment is not large.
6. Analysis of efficacy
Sex: 258 rhinitis patients are treated according to the group standard, wherein 45 patients with acute rhinitis and 50 patients with chronic rhinitis are treated; 41 cases of adenoid hypertrophy patients, 69 cases of allergic rhinitis patients and 53 cases of nasosinusitis patients;
the course of the disease is as follows: 75 cases are observed in 1 month to 5 months, 85 cases are observed in 6 months to 2 years, 45 cases are observed over 2 years, and 39 cases are observed over 5 years. 14 cases in more than 7 years
Age group: 108 cases in 4-20 years old, 97 cases in 20-30 years old, and 53 cases above 31 years old;
the types and the curative effects of the diseases are shown in table 1, and the administration time is two treatment courses.
As can be seen from table 1, the traditional Chinese medicine external patch for treating rhinitis provided by the invention has significant curative effects on diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis and nasosinusitis, the cure rate is 87%, the significant 10% and the effective 3%, the total effective rate reaches 100%, and the diseases are not easy to relapse.
Detailed Description
Example 1
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate;
a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis;
the preparation method of the external patch for treating rhinitis comprises the following steps:
(1) weighing the raw materials of the traditional Chinese medicine composition for treating rhinitis in parts by weight, drying, performing wall breaking and superfine grinding by a wall breaking machine to form fine powder of 250-350 meshes, and uniformly mixing to obtain the traditional Chinese medicine composition;
(2) taking 90-110g of medical pressure-sensitive hot melt adhesive, and putting the medical pressure-sensitive hot melt adhesive into a stainless steel pot to be heated and melted by slow fire;
(3) slowly adding the Chinese medicinal composition prepared in the step (1) into the mixture and stirring the mixture uniformly when the temperature is cooled to 72-78 ℃;
(4) when the temperature is cooled to 52-58 ℃, 4-6mL of azone, 2.5-3.5g of borneol and camphor are added respectively, and the mixture is uniformly stirred into paste, thus obtaining the mud flat;
(5) spreading the ointment on non-woven fabric, covering release paper, slicing, and packaging to obtain topical patch, wherein the weight of each patch is 1.8-2.0 g;
the external patch for treating rhinitis, which is prepared by adopting the raw material proportion and the method, can expel wind and clear heat, remove dampness and dredge orifices, and activate blood and remove blood stasis, can directly reach the focus by applying to Yintang acupoint, and can achieve good curative effects on rhinitis diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis, nasosinusitis, watery nasal discharge and the like, and has the advantages of quick response, short treatment course, simple use method and convenient carrying, can simultaneously condition three main and collateral channels of a human body, balance yin and yang, strengthen body resistance and eliminate pathogenic factors, can enhance immunity, and can overcome the defects that oral medicines are slow to absorb and can not directly reach the focus and the defect that western medicine has a single target spot.
Example 2
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 0.46 parts of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate;
a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis;
the preparation method of the external patch for treating rhinitis comprises the following steps:
(1) weighing the raw materials of the traditional Chinese medicine composition for treating rhinitis in parts by weight, drying, breaking the wall by a wall breaking machine, micronizing into fine powder of 300 meshes, and uniformly mixing to obtain the traditional Chinese medicine composition;
(2) taking 100g of medical pressure-sensitive hot melt adhesive, and putting the medical pressure-sensitive hot melt adhesive into a stainless steel pot to be heated and melted by mild fire;
(3) slowly adding the traditional Chinese medicine composition prepared in the step (1) into the mixture and stirring the mixture evenly when the temperature is cooled to 75 ℃;
(4) when the temperature is cooled to 55 ℃, 5mL of azone, 3g of borneol and camphor are added respectively, and the mixture is uniformly stirred into paste, thus obtaining the mud flat;
(5) spreading the ointment on non-woven fabric, covering release paper, slicing, and packaging to obtain topical patch, wherein the weight of each patch is 1.8-2.0 g;
the external patch for treating rhinitis, which is prepared by adopting the raw material proportion and the method, can expel wind and clear heat, remove dampness and dredge orifices, and activate blood and remove blood stasis, can directly reach the focus by applying to Yintang acupoint, and can achieve good curative effects on rhinitis diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis, nasosinusitis, watery nasal discharge and the like, and has the advantages of quick response, short treatment course, simple use method and convenient carrying, can simultaneously condition three main and collateral channels of a human body, balance yin and yang, strengthen body resistance and eliminate pathogenic factors, can enhance immunity, and can overcome the defects that oral medicines are slow to absorb and can not directly reach the focus and the defect that western medicine has a single target spot.
Example 3
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate;
a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis;
the preparation method of the external patch for treating rhinitis comprises the following steps:
(1) taking the cocklebur fruit, the loofah sponge, the pinellia tuber and the asarum in parts by weight, adding water with the volume ratio of (1: 5) - (1: 3) for soaking for 1 hour, heating and decocting for 2 times, boiling each time, then decocting for 20-30min, filtering to obtain liquid medicine, standing the liquid medicine decocted twice for 24-36h, filtering to obtain supernate, concentrating the supernate into a paste, and hanging flag or measuring the relative density by using a Bomei's hydrometer table to be 1.1-1.20 (70-80 ℃) for later use;
(2) drying the cantharis, the angelica dahurica, the bulbus fritilariae and the musk in weight, mixing and crushing the raw materials into fine powder of 250 meshes and 350 meshes, and placing the fine powder in a closed container for later use;
(3) taking 3.5-4 times of the total weight of the raw materials, melting with slow fire, cooling to 68-72 ℃, slowly adding the extract prepared in the step (1) under continuous stirring, fully and uniformly stirring, continuously heating with slow fire to remove water vapor, cooling to 48-52 ℃, adding the fine powder prepared in the step (2), and fully and uniformly stirring to form paste;
(4) spreading the paste prepared in the step (3) on non-woven fabrics, covering release paper, slicing, and packaging to obtain an external patch, wherein the weight of each patch is 1.8-2.0 g;
the external patch for treating rhinitis, which is prepared by adopting the raw material proportion and the method, can expel wind and clear heat, remove dampness and dredge orifices, and activate blood and remove blood stasis, can directly reach the focus by applying to Yintang acupoint, and can achieve good curative effects on rhinitis diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis, nasosinusitis, watery nasal discharge and the like, and has the advantages of quick response, short treatment course, simple use method and convenient carrying, can simultaneously condition three main and collateral channels of a human body, balance yin and yang, strengthen body resistance and eliminate pathogenic factors, can enhance immunity, and can overcome the defects that oral medicines are slow to absorb and can not directly reach the focus and the defect that western medicine has a single target spot.
Example 4
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate;
a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis;
the preparation method of the external patch for treating rhinitis comprises the following steps:
(1) drying the traditional Chinese medicines in parts by weight, mixing and crushing the traditional Chinese medicines into 100-mesh and 200-mesh fine powder, and placing the fine powder in a closed container for later use;
(2) soaking the traditional Chinese medicine mixture prepared in the step (1) with 70% ethanol leaching solution, and standing for 0.5-5h in a sealed manner until the fine powder is fully and uniformly wetted and expanded;
(3) uniformly loading the wetted medicine into a diacolation, soaking for 24-48h, slowly percolating, collecting percolate, and concentrating to obtain extract with relative density of 1.1-1.3;
(4) adding 11-13g of rubber paste matrix into the extract prepared in the step (3), spreading on a non-woven fabric, covering release paper, slicing, and packaging to obtain an external patch, wherein the weight of each patch is 1.8-2.0 g;
the external patch for treating rhinitis, which is prepared by adopting the raw material proportion and the method, can expel wind and clear heat, remove dampness and dredge orifices, and activate blood and remove blood stasis, can directly reach the focus by applying to Yintang acupoint, and can achieve good curative effects on rhinitis diseases such as acute rhinitis, chronic rhinitis, adenoid hypertrophy, allergic rhinitis, nasosinusitis, watery nasal discharge and the like, and has the advantages of quick response, short treatment course, simple use method and convenient carrying, can simultaneously condition three main and collateral channels of a human body, balance yin and yang, strengthen body resistance and eliminate pathogenic factors, can enhance immunity, and can overcome the defects that oral medicines are slow to absorb and can not directly reach the focus and the defect that western medicine has a single target spot.
Comparative example 1
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate; a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis; compared with the example 2, the specific preparation method is the same as the example 2, no musk is added, and the prepared external patch has poor curative effect and slow recovery for patients.
Comparative example 2
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.46 part of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate; a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis; compared with the example 2, the preparation method has the advantages that the cantharis is removed, the prepared external patch has little application effect on patients, and the symptoms of nasal obstruction and headache are not relieved.
Comparative example 3
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 0.46 parts of musk, 2.8 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 13 parts of pinellia ternate; a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis; compared with the example 2, the specific preparation method reduces the using amount of the angelica dahurica from 6.5 parts to 2.8 parts and increases the using amount of the pinellia ternate to 13 parts, so that the prepared external patch has obviously reduced effect and slower discomfort symptom relief.
Comparative example 4
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 0.46 parts of musk, 6.5 parts of angelica dahurica, 0.8 parts of asarum, 6 parts of cocklebur fruit, 7 parts of bulbus fritilariae, 11 parts of loofah sponge and 7.5 parts of pinellia ternate; a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis; compared with the example 2, the preparation method reduces the dosage of the asarum from 2 parts to 0.8 part, increases the dosage of the loofah sponge from 6.5 parts to 11 parts, and increases two treatment courses after the prepared external patch is used by patients.
Comparative example 5
A traditional Chinese medicine composition for treating rhinitis is prepared from the following raw materials in parts by weight: 0.008 part of cantharis, 0.03 part of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 2 parts of cocklebur fruit, 7 parts of bulbus fritilariae, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate; a topical patch for the treatment of rhinitis comprises the above Chinese medicinal composition for the treatment of rhinitis; compared with the example 2, the specific preparation method reduces the using amount of the cantharis from 0.035 to 0.008 parts, the using amount of the musk from 0.46 to 0.03 parts and the using amount of the cocklebur fruit from 6 to 2 parts by the same as the example 2, and the prepared external patch has the advantages that the symptoms of nasal obstruction and sneezing are not obviously relieved after the patch is used by patients, and the edema of nasal mucosa disappears slowly.
The formula of the traditional Chinese medicine composition for treating rhinitis provided by embodiments 3-25 of the invention is shown in tables 2-4.
Typical cases
Case one: in a forest, male, age 29, chronic rhinitis lasts for 22 years, the nasal obstruction and headache are accompanied, the breathing is not smooth, the forest can only breathe by using the mouth, the memory decline, the face deformation, the lateral bending of the nose bridge and the proud mouth are caused by the long-term incapability of breathing by using the nasal cavity, the effect is not obvious and the pain is abnormal through multi-prescription treatment; the external patch prepared in the embodiment 2 of the invention is used for treatment, the patch is attached to Yintang acupoint before sleep at night, the nose is smooth in the next morning, all symptoms are relieved, one treatment course is applied, the patch is cured, and the patch is followed for two years without recurrence.
Case two: for a certain woman in 15 years old, nasosinusitis, frequent headache and olfactory failure, the external patch prepared in the embodiment 2 of the invention is stuck on Yintang acupoint, the nose can smell the taste after 3 days, the headache is relieved, and a treatment course is continued, the recovery is realized, and the follow-up visit is carried out for two years without relapse.
Case three: wangzhi, male, 45 years old, allergic rhinitis for 25 years, nasal septum bending, nasal concha hypertrophy, easy outbreak in spring and autumn, aggravation in cold air, serious outbreak, rhinorrhea, lacrimation, sneezing, unsmooth breathing and snoring in night sleep, the external patch prepared by the embodiment 2 of the invention is stuck on Yintang acupoint, the symptom is relieved after one sticking, the patch is healed after one treatment course, and no relapse occurs after two years of follow-up.
Case four: when the patient is 8 years old, adenoids are large, the patient is not smooth to ventilate, the patient is in mouth breathing during sleep at night, the patient is in snoring, and the patient is informed of the need of operation treatment in the examination of the five sense organs in the local hospital, and the family is reluctant to perform the operation due to the small age. The external patch prepared in the embodiment 2 of the invention is stuck on Yintang acupoint, one patch is lightened, 5 patches are used for healing, and the disease does not relapse after three follow-up years.
Case five: the external patch prepared by the embodiment 2 of the invention is stuck to Yintang acupoint, heals once and does not relapse after two years of follow-up.
Claims (3)
1. The traditional Chinese medicine composition for treating rhinitis is characterized by being prepared from the following raw materials in parts by weight: 0.01-0.06 part of cantharis, 0.03-0.9 part of musk, 3-10 parts of angelica dahurica, 1-3 parts of asarum, 3-9 parts of cocklebur fruit, 3-11 parts of tendril-leaved fritillary bulb, 3-10 parts of loofah sponge and 3-12 parts of pinellia ternate.
2. The traditional Chinese medicine composition for treating rhinitis according to claim 1, which is prepared from the following raw materials in parts by weight: 0.035 parts of cantharis, 0.46 parts of musk, 6.5 parts of angelica dahurica, 2 parts of asarum, 6 parts of cocklebur fruit, 7 parts of tendril-leaved fritillary bulb, 6.5 parts of loofah sponge and 7.5 parts of pinellia ternate.
3. A patch for external use for treating rhinitis, which comprises the Chinese medicinal composition for treating rhinitis according to any one of claims 1 to 2.
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| CN103933321A (en) * | 2014-04-10 | 2014-07-23 | 李宝亮 | Traditional Chinese medicine composition for treating rhinitis and external paste and preparation method thereof |
| CN105055589A (en) * | 2015-08-14 | 2015-11-18 | 胡连华 | Rhinitis paste and preparation method thereof |
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| CN105055589A (en) * | 2015-08-14 | 2015-11-18 | 胡连华 | Rhinitis paste and preparation method thereof |
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| Title |
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| 中药喷雾治疗过敏性鼻炎130例;成正元等;《人民军医》;19971231;第40卷(第03期);第178-179页 * |
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