CN103751396B - External medical composition for treating gonarthromeningitis - Google Patents
External medical composition for treating gonarthromeningitis Download PDFInfo
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Abstract
The invention relates to an external medical composition for treating gonarthromeningitis. The composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 18-30 parts of huperzia serrata, 15-25 parts of semen brassicae, 18-30 parts of evodia lepta root, 18-30 parts of schisandra chinensis, 42-68 parts of red phaseolus bean, 15-25 parts of saposhnidoviae radix, 15-25 parts of cortex phellodendri and 10-17 parts of radix angelicae. When the external medical composition is used for treating gonarthromeningitis, the medical composition is used at an affected part directly, and is rapid in effectiveness and obvious in effects and has no obvious toxic or side effects.
Description
Technical field
The invention belongs to technical field of Chinese medicine, in particular to a kind of externally-applied medicinal composition being used for the treatment of gonarthromeningitis.
Background technology
One group of syndrome that gonarthromeningitis mainly causes because of sprain of knee joint and multiple intraarticular damage.Its main manifestations is arthremia swelling, pain, ooze out increase, difficulty, function limitation are squatted down in hydrarthrosis, activity.
Chinese medicine thinks that synovitis belongs to " arthromyodynia " category, articular synovitis is divided into and injures chronic strain two aspect outward.After on the beds such as knee joint suffers fractures, dislocate, ligament rapture, cartilage injury, synovium of joint all can be made simultaneously impaired.Long-pending stasis of blood hydrops after wound, damp and hotly wins mutually, and make knee joint heating, distending pain, scorching hot, muscle contracture, obstacle is bent and stretched in joint, formation acute synovitis; As injured comparatively light, or long-term chronic strain, wind and cold, damp invasion and attack can make knee engender swelling, dysfunction in addition, form chronic synovitis.
The method for the treatment of synovitis, western medicine is thought more, does not also have ability that the pathology of synovitis is reversed at present, and patient can only use analgesic, pain killer injection, take out hydrops etc. carrys out relief of symptoms.But ancients just propose its mechanism mainly because wind, cold, wet, pathogenic heat are attacked caused by joint, and emphasized that entirety treats, treatment must aim at the pathogenesis of disease in " interior through Plain Questions ".
Summary of the invention
In view of the deficiency that doctor trained in Western medicine exists treatment gonarthromeningitis, the object of the present invention is to provide a kind of external medicine composition being used for the treatment of gonarthromeningitis, this medicine instant effect, good effect, easy and simple to handle, without side reaction.
The object of the present invention is achieved like this:
Be used for the treatment of an externally-applied medicinal composition for gonarthromeningitis, said composition is prepared from by the traditional Chinese medicinal material raw materials comprising following weight portion: Herba Lycopodii serrati 18-30 part, Semen Sinapis Albae 15-25 part, trident bitter root 18-30 part, Fructus Schisandrae Chinensis 18-30 part, Semen Phaseoli 42-68 part, Radix Saposhnikoviae 15-25 part, Cortex Phellodendri 15-25 part, Radix Angelicae Dahuricae 10-17 part.
Preferably, be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as mentioned above, it is prepared from by the traditional Chinese medicinal material raw materials comprising following weight portion: Herba Lycopodii serrati 22-26 part, Semen Sinapis Albae 18-22 part, trident bitter root 22-26 part, Fructus Schisandrae Chinensis 22-26 part, Semen Phaseoli 50-60 part, Radix Saposhnikoviae 18-22 part, Cortex Phellodendri 18-22 part, Radix Angelicae Dahuricae 12-15 part.
In a most preferred embodiment of the present invention, be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as mentioned above, it is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Herba Lycopodii serrati 24 parts, Semen Sinapis Albae 20 parts, trident bitter root 24 parts, Fructus Schisandrae Chinensis 24 parts, Semen Phaseoli 50 parts, Radix Saposhnikoviae 20 parts, Cortex Phellodendri 20 parts, the Radix Angelicae Dahuricae 13 parts.
Further preferably, be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as mentioned above, it is prepared to gel, ointment, liniment.
The preparation method of the gel that the present invention relates to comprises the steps:
1) get the raw materials ready: by recipe quantity take clean up Herba Lycopodii serrati, Semen Sinapis Albae, trident bitter root, Fructus Schisandrae Chinensis, Semen Phaseoli, Radix Saposhnikoviae, Cortex Phellodendri and the Radix Angelicae Dahuricae, for subsequent use;
2) decoct: decoct with water, first decocts 8 times that every tank adds water as medical material total amount, and keep 3 hours after ebuillition of heated, extracting solution enters settling tank through 200 order metre filter; Second decocts the water heating extraction adding medical material amount 4 times, and protect and boil 3 hours, extracting solution enters settling tank through 200 order metre filter;
3) precipitate: extracting solution precipitation 24-36 hour in settling tank, extract supernatant through 200 order metre filter in triple effect evaporator, precipitate is by offal treatment;
4) concentrated: to be 1.00-1.10(40 DEG C of mensuration when supernatant is concentrated into relative density in triple effect evaporator) time, by rare clear paste in 200 order metre filter suction vacuum decompressioning and concentrating tanks, concentrating and being mixed to relative density is 1.30-1.32(90 DEG C of mensuration) time go out cream, to in storage cream bucket, for subsequent use;
5) dry: wherein vacuum :-0.1MPa, temperature: 78-82 DEG C, drying time 20-24 hour;
6) powder is beaten: smashing fineness 80 mesh sieve, obtains clear paste powder;
7) slowly joined in purified water by carbomer, limit edged stirs until form transparent gel-type vehicle, is dissolved in suitable quantity of water by clear paste powder, add again in substrate, stir, add propylene glycol, glycerol, purified water to full dose, triethanolamine adjust ph, to neutral, obtains gel.
According to Chinese medicine Historical Data Data About, the function of above-mentioned Chinese crude drug cures mainly and originates as follows:
Herba Lycopodii serrati: heat-clearing and toxic substances removing; Eliminating dampness and astringing sores; Hemostasis analgesic therapy dissipating blood stasis; Detumescence; Main pneumonia; Lung abscess; Over-strained hemoptysis; Hemorrhoidal hemorrhage; Leucorrhea; Traumatic injury; Toxic swelling; Water hygral expansion; Ulcer does not close up for a long time; Burn and scald; Select the herb of Huperziaceae stone araucaria herbaceos perennial Herba Lycopodii serrati;
Semen Sinapis Albae: warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving; Breath with cough for cold-phlegm, distending pain in the chest and hypochondrium, the stagnant meridians of expectorant, joint numbness, pain, phlegm-damp oozing in the body, carbuncle of yin nature toxic swelling; Select the dry mature seed of biennial plant Caulis et Folium Sinapis albee Sinapis alba L.;
Trident bitter root: heat-clearing and toxic substances removing, expelling wind and removing dampness; Control the diseases such as laryngopharynx swelling and pain, rheumatic ostalgia, malaria, jaundice, eczema, dermatitis, traumatic injury and worm venom; Select the dry root of Rutaceae Evodia plant Foliumet Ramulus Evodiae Evodia lepta (Spreng.) Merr.;
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, deficient pulse of losing heart, and interior-heat is quenched one's thirst, palpitation and insomnia;
Semen Phaseoli: diuretic disappears kind, removing toxic substances and promoting pus discharge; For edema distension, beriberi edema, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess; Select the dry mature seed of leguminous plant Semen Phaseoli Phaseolus angularis Wight;
Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely; Cure mainly diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus; For the root of Umbelliferae herbaceos perennial Radix Saposhnikoviae;
Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat; For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus; Select the dry bark of rutaceae wampee or Cortex Phellodendri;
The Radix Angelicae Dahuricae: wind-damp dispelling, evacuation of pus of invigorating blood circulation, granulation promoting pain relieving; For headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus; Select the root of samphire angelica anomala.
Compared with prior art, the externally-applied medicinal composition that the present invention relates to makes the through sick place of medicine when treating gonarthromeningitis, rapid-action, acts on obviously, and without obvious toxic and side effects.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
The preparation of embodiment 1 Chinese medicine gel
Crude drug prescription: Herba Lycopodii serrati 2.4 kilograms, Semen Sinapis Albae 2 kilograms, trident bitter root 2.4 kilograms, Fructus Schisandrae Chinensis 2.4 kilograms, Semen Phaseoli 5 kilograms, Radix Saposhnikoviae 2 kilograms, Cortex Phellodendri 2 kilograms, the Radix Angelicae Dahuricae 1.3 kilograms.
Gel preparation method:
1) get the raw materials ready: take the above-mentioned Chinese crude drug cleaned up by recipe quantity, for subsequent use;
2) decoct: decoct with water, first decocts 8 times that every tank adds water as medical material total amount, and keep 3 hours after ebuillition of heated, extracting solution enters settling tank through 200 order metre filter; Second decocts the water heating extraction adding medical material amount 4 times, and protect and boil 3 hours, extracting solution enters settling tank through 200 order metre filter;
3) precipitate: in settling tank, extracting solution precipitates 30 hours, extract supernatant through 200 order metre filter in triple effect evaporator, precipitate is by offal treatment;
4) concentrated: to be 1.05(40 DEG C of mensuration when supernatant is concentrated into relative density in triple effect evaporator) time, by rare clear paste in 200 order metre filter suction vacuum decompressioning and concentrating tanks, concentrating and being mixed to relative density is 1.30-1.32(90 DEG C of mensuration) time go out cream, in storage cream bucket, for subsequent use;
5) dry: wherein vacuum :-0.1MPa, temperature: 78-82 DEG C, 24 hours drying times;
6) powder is beaten: smashing fineness 80 mesh sieve, obtains clear paste powder;
7) 10g carbomer is slowly joined in the purified water of about 500ml, limit edged stirs until form transparent gel-type vehicle, 1g clear paste powder is dissolved in suitable quantity of water, add again in gel-type vehicle, stir, add 60ml propylene glycol, 50ml glycerol, purified water to 1000ml, triethanolamine adjust ph, to neutral, to obtain final product.
The preparation of embodiment 2 Chinese medicine gel
Crude drug prescription: Herba Lycopodii serrati 3 kilograms, Semen Sinapis Albae 2.5 kilograms, trident bitter root 2 kilograms, Fructus Schisandrae Chinensis 2.5 kilograms, Semen Phaseoli 6 kilograms, Radix Saposhnikoviae 2.3 kilograms, Cortex Phellodendri 2.5 kilograms, the Radix Angelicae Dahuricae 1 kilogram.
Gel preparation method is with embodiment 1.
The preparation of embodiment 3 Chinese medicine gel
Crude drug prescription: Herba Lycopodii serrati 2 kilograms, Semen Sinapis Albae 2 kilograms, trident bitter root 3 kilograms, Fructus Schisandrae Chinensis 1.8 kilograms, Semen Phaseoli 4.2 kilograms, Radix Saposhnikoviae 1.5 kilograms, Cortex Phellodendri 1.5 kilograms, the Radix Angelicae Dahuricae 1.7 kilograms.
Gel preparation method is with embodiment 1.
The preparation of embodiment 4 Chinese medicine gel
Crude drug prescription: Herba Lycopodii serrati 2.2 kilograms, Semen Sinapis Albae 2.2 kilograms, trident bitter root 2.2 kilograms, Fructus Schisandrae Chinensis 2.2 kilograms, Semen Phaseoli 6 kilograms, Radix Saposhnikoviae 1.8 kilograms, Cortex Phellodendri 1.8 kilograms, the Radix Angelicae Dahuricae 1.2 kilograms.
Gel preparation method is with embodiment 1.
Embodiment 5 Chinese medicine gel is to the effectiveness study of gonarthromeningitis patient
Gonarthromeningitis patient 33 example made a definite diagnosis after diagnosing, wherein man 18 example, female 15 example, 37 years old-62 years old age, 44.1 ± 3.7 years old mean age.The knee joint of patient all has swelling, pain, movable function limited.Have a medical check-up: Xiyan place protuberance is full, and floating patella test is positive.According to the number of joint fluid, 3d-5d drawing liquid 1 time or 2 times, pressure dressing after drawing liquid, venoclysis antibiotic is avoided infection.Then, patient selects the Traditional Chinese medicine gel prepared according to prescription and the technique of the embodiment of the present invention 1 to carry out external application, with bundle around 4h-6h, can play the warming effect with preventing drug contamination medicated clothing in local outside drug gel.After Traditional Chinese Medicine for external application, note observing local skin swelling with or without disappearing, skin temperature with or without changing, the pain of patient with or without alleviating, and local skin is with or without anaphylaxis.Every day sooner or later respectively once, presses following standard rating curative effect after 1 week:
Recovery from illness: knee joint swelling, pain disappear, and function of joint is normal;
Take a turn for the better: knee joint swelling, pain relief;
Invalid: knee joint swelling, pain are without alleviation.
In 33 routine gonarthromeningitis patients, by using Chinese medicine gel external application of the present invention targetedly, recovery from illness 29 examples (87.9%) after 1 week, 3 examples that take a turn for the better (9.1%), invalid 1 example (3.0%), total effective rate 97.0%.
Claims (4)
1. be used for the treatment of an externally-applied medicinal composition for gonarthromeningitis, it is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Herba Lycopodii serrati 18-30 part, Semen Sinapis Albae 15-25 part, trident bitter root 18-30 part, Fructus Schisandrae Chinensis 18-30 part, Semen Phaseoli 42-68 part, Radix Saposhnikoviae 15-25 part, Cortex Phellodendri 15-25 part, Radix Angelicae Dahuricae 10-17 part.
2. be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as claimed in claim 1, it is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Herba Lycopodii serrati 22-26 part, Semen Sinapis Albae 18-22 part, trident bitter root 22-26 part, Fructus Schisandrae Chinensis 22-26 part, Semen Phaseoli 50-60 part, Radix Saposhnikoviae 18-22 part, Cortex Phellodendri 18-22 part, Radix Angelicae Dahuricae 12-15 part.
3. be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as claimed in claim 2, it is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Herba Lycopodii serrati 24 parts, Semen Sinapis Albae 20 parts, trident bitter root 24 parts, Fructus Schisandrae Chinensis 24 parts, Semen Phaseoli 50 parts, Radix Saposhnikoviae 20 parts, Cortex Phellodendri 20 parts, the Radix Angelicae Dahuricae 13 parts.
4. be used for the treatment of the externally-applied medicinal composition of gonarthromeningitis as claimed in claim 1 or 2, it is characterized in that: described compositions is gel, ointment, liniment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410044294.8A CN103751396B (en) | 2014-02-01 | 2014-02-01 | External medical composition for treating gonarthromeningitis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410044294.8A CN103751396B (en) | 2014-02-01 | 2014-02-01 | External medical composition for treating gonarthromeningitis |
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| CN103751396A CN103751396A (en) | 2014-04-30 |
| CN103751396B true CN103751396B (en) | 2015-03-11 |
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| CN104056016A (en) * | 2014-06-09 | 2014-09-24 | 青岛申达高新技术开发有限公司 | Fumigation care solution for treating knee osteoarthritis |
| CN105535682A (en) * | 2016-01-14 | 2016-05-04 | 田均庆 | External-application traditional Chinese medicine for treating traumatic synovitis of knee joint and preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721484A (en) * | 2009-12-21 | 2010-06-09 | 宋栓牛 | Traditional Chinese medicine externally-applied agent for treating gonarthromeningitis and preparation method thereof |
| CN102327339A (en) * | 2011-09-10 | 2012-01-25 | 杨玉宝 | Traditional Chinese medicine synovium inflammation-removing plaster for treating chronic gonarthromeningitis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721484A (en) * | 2009-12-21 | 2010-06-09 | 宋栓牛 | Traditional Chinese medicine externally-applied agent for treating gonarthromeningitis and preparation method thereof |
| CN102327339A (en) * | 2011-09-10 | 2012-01-25 | 杨玉宝 | Traditional Chinese medicine synovium inflammation-removing plaster for treating chronic gonarthromeningitis |
Non-Patent Citations (2)
| Title |
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| 中西医结合综合治疗膝关节滑膜炎的临川观察;张斌等;《四川中医》;20061231;第24卷(第1期);74-75 * |
| 膝关节滑膜炎的治疗与康复;牟秀华;《中医中药》;20111231(第1期);123 * |
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