CN104027426A - Traditional Chinese medicine drops for treating rhinitis - Google Patents
Traditional Chinese medicine drops for treating rhinitis Download PDFInfo
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- CN104027426A CN104027426A CN201410296962.6A CN201410296962A CN104027426A CN 104027426 A CN104027426 A CN 104027426A CN 201410296962 A CN201410296962 A CN 201410296962A CN 104027426 A CN104027426 A CN 104027426A
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Abstract
The invention discloses traditional Chinese medicine drops for treating rhinitis. The traditional Chinese medicine drops are prepared from the following traditional Chinese medicine materials in parts by weight: 15-45 parts of astragalus, 5-30 parts of roasted bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 5-25 parts of pulp of fructus mume, 5-25 parts of bupleurum falcatum, 5-15 parts of magnolia flower, 5-15 parts of fried xanthium sibiricum, 3-8 parts of as arum, 3-8 parts of ephedra, 5-25 parts of periostracum cicada and 5-15 parts of liquorice. The traditional Chinese medicine drops disclosed by the invention are obvious in curative effect for treating rhinitis, low in treatment cost, and have the advantages of being small in side effect, convenient to take, and the like.
Description
Technical field:
The present invention relates to Chinese medicine technical field, is exactly a kind of Chinese medicine drop for the treatment of rhinitis specifically.
Background technology:
Rhinitis is nasal cavity inflammatory diseases, is the inflammation of the bronchia mucosal that causes of virus, antibacterial, allergen, various physical and chemical factor and some systemic disease.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hypertrophy, atrophy or downright bad etc.Doctor trained in Western medicine mainly adopts antibiosis usually to carry out bactericidal antiphlogistic and treats, but medical expense is relatively high and the rear easily recurrence for the treatment of; The traditional Chinese medical science is lower with medical expense, but oral Chinese medicine, not only mouthfeel extreme difference, so and because the focus treatment of can not going directly is also longer the course for the treatment of, brought many inconvenience.
Summary of the invention:
The present invention is exactly in order to overcome the deficiencies in the prior art, provide one have curative effect obviously, can go directly focus, medical expense of medicine be cheap, and the Chinese medicine drop of the little treatment rhinitis of side effect.
The invention provides following technical scheme:
A kind of Chinese medicine drop for the treatment of rhinitis, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: Radix Astragali 15-45 part, Rhizoma Atractylodis Macrocephalae (parched) 5-30 part, Radix Saposhnikoviae 5-15 part, Fructus Mume 5-25 part, Radix Stellariae 5-25 part, Flos Magnoliae 5-15 part, fries Herba Xanthii 5-15 part, Herba Asari 3-8 part, Herba Ephedrae 3-8 part, Periostracum Cicadae 5-25 part, Radix Glycyrrhizae 5-15 part.
Formula optimization is:
30 parts of the Radixs Astragali, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 8 parts of Radix Saposhnikoviaes, 15 parts of Fructus Mume, 10 parts of Radix Stellariaes, 10 parts of Flos Magnoliae, fry 10 parts of Herba Xanthiis, 5 parts of Herba Asaris, 5 parts, Herba Ephedrae, 15 parts of Periostracum Cicadaes, 6 parts, Radix Glycyrrhizae.
Preparation and using method:
The Radix Astragali, Fructus Mume are decocted inferior, the extractum that is condensed into 1.10 concentration after merging medicinal liquid at 50 DEG C of temperature is for subsequent use, other medicines are tentatively ground into granule, the ether of putting into 51 ° soaks 5 days, to constantly rock during this time and keep medicated powder in ether, to become suspended state, in the time of the 6th day, add the extractum of the Radix Astragali, Fructus Mume, stir, until extractum after dissolving completely static 48 hours again, gained supernatant is Chinese medicine drop of the present invention.
Sooner or later used twice every day, can directly splash into nasal cavity, also can first drop on cotton swab, then cotton swab be stretched into nasal cavity and press 30 seconds.
Pharmacology, the drug effect of the each raw material of Chinese medicine of composition the present invention are described as follows:
The Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effects such as expelling pus and promoting granulation.Be usually used in the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, the diseases such as diabetes.Research shows: 1, normal rat is raised with containing the affairs of Radix Astragali powder after 1 week, before surveying its oxygen consumption ratio and taking medicine, increases gradually.2, can strengthen normal heart and shrink, the heart of exhaustion is had to cardiotonic.3, this product can make tubular blood vessel and renal blood vessels expansion, and makes the expansion of whole body peripheral vessel, and skin circulation is freely contained, and makes hyperpietic's blood pressure drops.4, experimenter has carried out diuretic test on one's body, proves that the Radix Astragali has medium diuresis.5, the Radix Astragali is clayed into power and is added feedstuff to feed 3 to rat, has the effect of preventing Jishengshenqiwan.6, the Radix Astragali has sedation to white mice, can maintain a few hours.7, rabbit oral administration astragalus, can make blood glucose obviously decline.8, rat isolated uterine is had to excitation-contraction effect.9, bacteriostatic test: this product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.There is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, the effect such as antiabortive.Be usually used in insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, the diseases such as frequent fetal movement.The Rhizoma Atractylodis Macrocephalae can significantly strengthen the ability of leukocytes phagocytic staphylococcus aureus; Rhizoma Atractylodis polysaccharide has the effect of recovery to lymphocytic propagation function, and improves the survival rate of immunosuppressed mice spleen cell In vitro culture, extends lymphocyte life span, corrects T subsets distribution disturbance state, can make low IL-2 level significantly improve; The Rhizoma Atractylodis Macrocephalae has the effect of resisting fatigue and adrenal cortex reinforcing function; The Rhizoma Atractylodis Macrocephalae has the mouse red blood cell of promotion hemoposieis; Rhizoma Atractylodis Macrocephalae Wheat Protein, can effectively suppress lipid peroxidation, reduces the content of organizing lipid peroxide, avoids the destruction of harmful substance to histiocyte 26S Proteasome Structure and Function, can resist mice and human red blood cell autoxidation haemolysis.In addition, this product also has the effects such as blood sugar lowering, anticoagulation, antitumor, antioxidation, slow down aging.The Rhizoma Atractylodis Macrocephalae that parched with bran is crossed can relax dry property, in entering, strengthens spleen invigorating, detumescence effect by means of bran.
Radix Saposhnikoviae: acrid in the mouth; Sweet; Slightly warm in nature.Return bladder, lung, spleen, Liver Channel.There is expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, the effect such as antipruritic.Be usually used in treating affection of exogenous wind-cold; Headache general pain; Rheumatic arthralgia; Joint is ached; Stomachache is had loose bowels; Discharging fresh blood stool; Tetanus; Rubella pruritus; Skin infection is from the beginning of waiting disease.This product also has analgesia, calmness, antiallergic, the effect such as antipyretic, antibacterial.
Fructus Mume: sour in the mouth, puckery, property is flat.Return liver, spleen, lung, large intestine channel.Have and astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, the effects such as relieving colic caused by ascaris.Be usually used in chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, the diseases such as ascariasis of biliary tract.Fructus Mume has inhibitory action to various pathogens, as dysentery bacterium, escherichia coli, Bacillus typhi, Salmonella paratyphi, bordetella pertussis, meningococcus etc.Tubercule bacillus is also had to inhibition effect, and this effect may be relevant with contained citric acid and malic acid.Some pathogenic fungus is also had to inhibitory action as tinea barbae tinea, acrothesium floccosum, Gypsum Fibrosum sample microspore bacterium etc.
Radix Stellariae: sweet in the mouth, cold nature.Return liver, stomach warp.There is clearind deficient heat, the effects such as dispelling fever with infantile malnutrition.Be usually used in fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, the diseases such as children's's infantile malnutrition with fever.This product child has antibacterial, reduces serum ornitrol concentration, and can make aorta lipoids content reduce; Saponin can act on plasma lipoprotein, stops cholesteric esterification and the deposition in blood vessel wall thereof, also can stop cholesterol from intestinal absorption etc.Radix Stellariae can clearind deficient heat, dispelling fever with infantile malnutrition, also has good antibacterial action.
Flos Magnoliae: acrid in the mouth, warm in nature.Attach to the lung and stomach meridians.There is dispersing wind and cold, the effects such as clearing the nasal passage.Be usually used in headche due to wind-cold, nasal obstruction, nasal sinusitis, the diseases such as turbid nasal discharge.This product also has antiallergic, blood pressure lowering and multiple pathogenic fungus is had to inhibitory action.
Herba Xanthii: bitter in the mouth; Pungent; Cold nature; Mild toxicity.Return lung; Spleen; Liver Channel.Have and dispel the wind; Heat radiation; Dehumidifying; Removing toxic substances.Main flu; Wind syndrome of head; Dizzy; The diseases such as nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery.This product has remarkable hypoglycemic activity; Decoct has antitussive effect; Heart is had to inhibitory action, make decreased heart rate, contractility weakens; Staphylococcus aureus, group B streptococcus, Diplococcus pneumoniae are had to certain inhibitory action, and have antifungic action.
Herba Asari: acrid in the mouth, warm in nature.GUIXIN, lung, kidney channel.There is the cold expelling of inducing sweat, wind-expelling pain-stopping, sensible, the effects such as warming the lung to resolve fluid-retention.Be usually used in anemofrigid cold, headache, toothache, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, the phlegm retention disease such as breath with cough.Research shows: this product also has antipyretic effect; Herba Asari volatile oil can obviously increase the coronary flow of guinea pig isolated heart; And energy blood pressure lowering, and decoct can boost; The tracheal smooth muscle that Herba Asari volatile oil causes convulsion to histamine or acetylcholine has the relexation of highly significant, and its antihistamine effect is strong compared with anti-acetylcholine.
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature.Return lung, urinary bladder channel.There is diaphoresis cold expelling, depressed lung-energy dispersing, the effects such as inducing diuresis to remove edema.Be usually used in anemofrigid cold, uncomfortable in chest breathing with cough, edema due to wind pathogen edema; Bronchial asthma.Honey Herba Ephedrae nourishing the lung to arrest cough.Be used for showing disease and separate, the diseases such as asthma and cough.In this product, contained ephedrine has the effect of adrenomimetic drug sample; it is by discharging mediator (indirect action); and direct exciting α and B-adrenergic receptor; lax bronchial smooth muscle; excited heart; rising blood pressure, can be in order to treat bronchial asthma and hypotension, and can stimulating central nervous system system; Heavy dose can cause mental excitation, uneasiness and insomnia, contract skin, mucosa blood vessel, and collunarium can be eliminated the nasal obstruction that nasal mucosa hyperemia causes, or in order to treat urticaria, vasodilation etc.When pseudoephedrine low concentration, similar to ephedrine to bronchial spasmolysis, boost and obviously weaken with platycoria effect.Pseudoephedrine has significant diuresis compared with ephedrine, and ephedrine and pseudoephedrine all have excitation to striped muscle, can be used for treating myasthenia gravis.Ephedine can reduce blood pressure.Herba Ephedrae volatile oil Emulsion gavage, has refrigeration function to the rabbit of artificial fever; Its main constituent terpineol is stronger to mice cooling effect, but cat and people are had no to perspiration, once has report Herba Ephedrae volatile oil to have inhibitory action to some influenza virus.
Periostracum Cicadae: sweet in the mouth, cold in nature.Return lung, Liver Channel.There is loose wind heat extraction, sore-throat relieving, rash, nebula removing, the effects such as spasmolytic.Be usually used in anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, the diseases such as tetanus.This product also has capillary permeability, convulsion, calmness, the analgesia of reduction, erythrocyte is had certain protective effect, slows down the effect such as heart rate and antiallergic.
Radix Glycyrrhizae: sweet in the mouth, property is flat.Return stomach, lung, spleen channel.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.This product has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic, anticancer, regulate body's immunity, arrhythmia, blood fat reducing, anti-
atherosclerosis, the pharmacological action such as anticoagulant, antitumor.
Advantage of the present invention:
The present invention has for the treatment of rhinitis that curative effect is obvious, medical expense is cheap, and the advantage such as side effect is little, medication is convenient.
Detailed description of the invention:
Embodiment 1:
Treat a Chinese medicine drop for rhinitis, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 30 parts of the Radixs Astragali, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 8 parts of Radix Saposhnikoviaes, 15 parts of Fructus Mume, 10 parts of Radix Stellariaes, 10 parts of Flos Magnoliae, fry 10 parts of Herba Xanthiis, 5 parts of Herba Asaris, 5 parts, Herba Ephedrae, 15 parts of Periostracum Cicadaes, 6 parts, Radix Glycyrrhizae.
Preparation and using method:
The Radix Astragali, Fructus Mume are decocted inferior, the extractum that is condensed into 1.10 concentration after merging medicinal liquid at 50 DEG C of temperature is for subsequent use, other medicines are tentatively ground into granule, the ether of putting into 51 ° soaks 5 days, to constantly rock during this time and keep medicated powder in ether, to become suspended state, in the time of the 6th day, add the extractum of the Radix Astragali, Fructus Mume, stir, until extractum after dissolving completely static 48 hours again, gained supernatant is Chinese medicine drop of the present invention.
Sooner or later used twice every day, can directly splash into nasal cavity, also can first drop on cotton swab, then cotton swab be stretched into nasal cavity and press 30 seconds.
Embodiment 2:
Treat a Chinese medicine drop for rhinitis, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 15 parts of the Radixs Astragali, 8 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 8 parts of Radix Saposhnikoviaes, 8 parts of Fructus Mume, 15 parts of Radix Stellariaes, 12 parts of Flos Magnoliae, fry 8 parts of Herba Xanthiis, 5 parts of Herba Asaris, 6 parts, Herba Ephedrae, 17 parts of Periostracum Cicadaes, 10 parts, Radix Glycyrrhizae.
Preparation and using method:
The Radix Astragali, Fructus Mume are decocted inferior, the extractum that is condensed into 1.10 concentration after merging medicinal liquid at 50 DEG C of temperature is for subsequent use, other medicines are tentatively ground into granule, the ether of putting into 51 ° soaks 5 days, to constantly rock during this time and keep medicated powder in ether, to become suspended state, in the time of the 6th day, add the extractum of the Radix Astragali, Fructus Mume, stir, until extractum after dissolving completely static 48 hours again, gained supernatant is Chinese medicine drop of the present invention.
Sooner or later used twice every day, can directly splash into nasal cavity, also can first drop on cotton swab, then cotton swab be stretched into nasal cavity and press 30 seconds.
Embodiment 3:
Treat a Chinese medicine drop for rhinitis, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 33 parts of the Radixs Astragali, 25 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Radix Saposhnikoviaes, 15 parts of Fructus Mume, 20 parts of Radix Stellariaes, 15 parts of Flos Magnoliae, fry 13 parts of Herba Xanthiis, 8 parts of Herba Asaris, 8 parts, Herba Ephedrae, 20 parts of Periostracum Cicadaes, 15 parts, Radix Glycyrrhizae.
Preparation and using method:
The Radix Astragali, Fructus Mume are decocted inferior, the extractum that is condensed into 1.10 concentration after merging medicinal liquid at 50 DEG C of temperature is for subsequent use, other medicines are tentatively ground into granule, the ether of putting into 51 ° soaks 5 days, to constantly rock during this time and keep medicated powder in ether, to become suspended state, in the time of the 6th day, add the extractum of the Radix Astragali, Fructus Mume, stir, until extractum after dissolving completely static 48 hours again, gained supernatant is Chinese medicine drop of the present invention.
Sooner or later used twice every day, can directly splash into nasal cavity, also can first drop on cotton swab, then cotton swab be stretched into nasal cavity and press 30 seconds.
General data:
Through clinical observation, in 242 routine acute and chronic rhinitis patients on the books, wherein male's 162 examples, women's 80 examples, wherein the longest 20 years of the course of disease, the shortest 1 year.The present invention has good curative effect to acute rhinitis, chronic rhinitis, wherein cure rate 71.6%, obvious effective rate 18.9%, effective percentage 5.6%, and total effective rate reaches 96. 1%.
Criterion of therapeutical effect:
Recovery from illness: symptom all disappears, and nasal cavity inspection is normal.
Effective: nasal obstruction, watery nasal discharge transference cure or obviously improvement, nasal cavity inspection sign is obviously improved.
Effective: nasal obstruction, watery nasal discharge symptom alleviate, local sign is improved.
Invalid: sings and symptoms is not improved.
Model case:
Case 1, Zhao, female, 52 years old, suffer from chronic simple rhinitis, nasal mucosa hyperemia, swelling, be kermesinus, intermittent nasal obstruction, nasal mucus amount is many, and the course of disease is longer, and after tired, sense is cold, symptom increases the weight of, and treats and does not feel any better with multiple Chinese and western drugs.Introduce and find inventor in June, 2007 through ward mate, and with the nasal drop that uses the embodiment of the present invention 1 to prepare, medication nasal mucosa hyperemia after one month, swelling symptom alleviate, and nasal obstruction, giddy, tinnitus symptom alleviate, and continues the after treatment of medication two weeks, cures; Follow up a case by regular visits to repeatedly, so far not recurrence.
Case 2, Chen, man, 46 years old, suffers from chronic hypertrophic rhinitis, have a stuffy nose heavier, have closed rhinolalia, hyposmia, has glutinous purulence nasal mucus, and with symptoms such as headache, giddy, insomnia and lethargy, once at the multiple western medicines in treatment of large hospital, bad when fashion, often repeatedly.Use the nasal drop prepared of the embodiment of the present invention 2, the medication symptom of having a stuffy nose after 1 month alleviates, and the symptoms such as headache, giddy, insomnia are obviously improved, and spirit takes a turn for the better, and continues medication and treats for 1 month, healing; Follow up a case by regular visits to repeatedly, so far not recurrence.
Case 3, poplar, man, 25 years old, suffer from acute rhinitis, there are the symptoms such as nasal obstruction, sneeze, thin nasal discharge, nasal mucosa hyperemia, nasal cavity secretions increase.2 weeks rear nasal obstruction symptoms of medication alleviate, and nasal mucosa hyperemia alleviates, and nasal cavity secretions reduces, and continues medication 2 weeks, cures; So far not recurrence.
Claims (2)
1. treat the Chinese medicine drop of rhinitis for one kind, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: Radix Astragali 15-45 part, Rhizoma Atractylodis Macrocephalae (parched) 5-30 part, Radix Saposhnikoviae 5-15 part, Fructus Mume 5-25 part, Radix Stellariae 5-25 part, Flos Magnoliae 5-15 part, fries Herba Xanthii 5-15 part, Herba Asari 3-8 part, Herba Ephedrae 3-8 part, Periostracum Cicadae 5-25 part, Radix Glycyrrhizae 5-15 part.
2. according to a kind of Chinese medicine drop for the treatment of rhinitis described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following composition by weight: 30 parts of the Radixs Astragali, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 8 parts of Radix Saposhnikoviaes, 15 parts of Fructus Mume, 10 parts of Radix Stellariaes, 10 parts of Flos Magnoliae, fry 10 parts of Herba Xanthiis, 5 parts of Herba Asaris, 5 parts, Herba Ephedrae, 15 parts of Periostracum Cicadaes, 6 parts, Radix Glycyrrhizae.
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| CN201410296962.6A CN104027426A (en) | 2014-06-28 | 2014-06-28 | Traditional Chinese medicine drops for treating rhinitis |
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| CN201410296962.6A CN104027426A (en) | 2014-06-28 | 2014-06-28 | Traditional Chinese medicine drops for treating rhinitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105030953A (en) * | 2015-06-30 | 2015-11-11 | 赵德欣 | Allergic rhinitis treatment traditional Chinese medicine composition and preparation method thereof |
| CN105596516A (en) * | 2014-11-19 | 2016-05-25 | 张凤梅 | Nasal cavity cleaning liquid |
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| CN101537089A (en) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | Pharmaceutical composition for curing allergic rhinitis and preparation method thereof |
| CN103736072A (en) * | 2014-01-28 | 2014-04-23 | 张怀胜 | Medicament for treating allergic rhinitis and preparation method of medicament |
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2014
- 2014-06-28 CN CN201410296962.6A patent/CN104027426A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101537089A (en) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | Pharmaceutical composition for curing allergic rhinitis and preparation method thereof |
| CN103736072A (en) * | 2014-01-28 | 2014-04-23 | 张怀胜 | Medicament for treating allergic rhinitis and preparation method of medicament |
Non-Patent Citations (1)
| Title |
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| 杨莹菲等: "乌梅化学成分、临床应用及现代药理研究进展", 《中国药师》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596516A (en) * | 2014-11-19 | 2016-05-25 | 张凤梅 | Nasal cavity cleaning liquid |
| CN105030953A (en) * | 2015-06-30 | 2015-11-11 | 赵德欣 | Allergic rhinitis treatment traditional Chinese medicine composition and preparation method thereof |
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Application publication date: 20140910 |