CN102626479B - External-use Chinese herbal medicine composition for chronic rheumatism treatment - Google Patents
External-use Chinese herbal medicine composition for chronic rheumatism treatment Download PDFInfo
- Publication number
- CN102626479B CN102626479B CN201210120839.XA CN201210120839A CN102626479B CN 102626479 B CN102626479 B CN 102626479B CN 201210120839 A CN201210120839 A CN 201210120839A CN 102626479 B CN102626479 B CN 102626479B
- Authority
- CN
- China
- Prior art keywords
- herbal medicine
- chinese herbal
- radix
- external
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 15
- 241000411851 herbal medicine Species 0.000 title claims abstract description 12
- 230000001684 chronic effect Effects 0.000 title abstract description 3
- 208000025747 Rheumatic disease Diseases 0.000 claims description 11
- 230000000552 rheumatic effect Effects 0.000 claims description 11
- 241000628997 Flos Species 0.000 claims description 5
- 241000283690 Bos taurus Species 0.000 claims description 4
- 239000008361 herbal raw material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 24
- 241001077909 Sigesbeckia Species 0.000 abstract description 2
- 244000205574 Acorus calamus Species 0.000 abstract 1
- 235000006480 Acorus calamus Nutrition 0.000 abstract 1
- 241000759271 Alangium Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000058073 Cynanchum mooreanum Species 0.000 abstract 1
- 241001022083 Flemingia Species 0.000 abstract 1
- 241000219138 Luffa Species 0.000 abstract 1
- 235000003956 Luffa Nutrition 0.000 abstract 1
- 244000302544 Luffa aegyptiaca Species 0.000 abstract 1
- 235000009814 Luffa aegyptiaca Nutrition 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 10
- 239000003814 drug Substances 0.000 description 9
- 208000006820 Arthralgia Diseases 0.000 description 6
- 230000003110 anti-inflammatory effect Effects 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 230000036772 blood pressure Effects 0.000 description 6
- 230000036407 pain Effects 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 210000004291 uterus Anatomy 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000001077 hypotensive effect Effects 0.000 description 3
- 210000000629 knee joint Anatomy 0.000 description 3
- 231100000862 numbness Toxicity 0.000 description 3
- 230000008736 traumatic injury Effects 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 208000000094 Chronic Pain Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- SLLMHZXMVHNZOR-UHFFFAOYSA-N Kakuol Chemical compound C1=C(O)C(C(=O)CC)=CC2=C1OCO2 SLLMHZXMVHNZOR-UHFFFAOYSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 206010062575 Muscle contracture Diseases 0.000 description 2
- ZYEMGPIYFIJGTP-UHFFFAOYSA-N O-methyleugenol Chemical compound COC1=CC=C(CC=C)C=C1OC ZYEMGPIYFIJGTP-UHFFFAOYSA-N 0.000 description 2
- FYRHTIWFKXZWAD-UHFFFAOYSA-N Sarisan Chemical compound C1=C(CC=C)C(OC)=CC2=C1OCO2 FYRHTIWFKXZWAD-UHFFFAOYSA-N 0.000 description 2
- 208000008765 Sciatica Diseases 0.000 description 2
- 230000036592 analgesia Effects 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000000954 anitussive effect Effects 0.000 description 2
- 206010003119 arrhythmia Diseases 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 208000006111 contracture Diseases 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 201000003068 rheumatic fever Diseases 0.000 description 2
- QMGVPVSNSZLJIA-FVWCLLPLSA-N strychnine Chemical compound O([C@H]1CC(N([C@H]2[C@H]1[C@H]1C3)C=4C5=CC=CC=4)=O)CC=C1CN1[C@@H]3[C@]25CC1 QMGVPVSNSZLJIA-FVWCLLPLSA-N 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- XFSBVAOIAHNAPC-XTHSEXKGSA-N 16-Ethyl-1alpha,6alpha,19beta-trimethoxy-4-(methoxymethyl)-aconitane-3alpha,8,10alpha,11,18alpha-pentol, 8-acetate 10-benzoate Chemical compound O([C@H]1[C@]2(O)C[C@H]3[C@@]45C6[C@@H]([C@@]([C@H]31)(OC(C)=O)[C@@H](O)[C@@H]2OC)[C@H](OC)[C@@H]4[C@]([C@@H](C[C@@H]5OC)O)(COC)CN6CC)C(=O)C1=CC=CC=C1 XFSBVAOIAHNAPC-XTHSEXKGSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- LPMXVESGRSUGHW-UHFFFAOYSA-N Acolongiflorosid K Natural products OC1C(O)C(O)C(C)OC1OC1CC2(O)CCC3C4(O)CCC(C=5COC(=O)C=5)C4(C)CC(O)C3C2(CO)C(O)C1 LPMXVESGRSUGHW-UHFFFAOYSA-N 0.000 description 1
- XFSBVAOIAHNAPC-UHFFFAOYSA-N Aconitin Natural products CCN1CC(C(CC2OC)O)(COC)C3C(OC)C(C(C45)(OC(C)=O)C(O)C6OC)C1C32C4CC6(O)C5OC(=O)C1=CC=CC=C1 XFSBVAOIAHNAPC-UHFFFAOYSA-N 0.000 description 1
- 241000717739 Boswellia sacra Species 0.000 description 1
- 241000269417 Bufo Species 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 239000004863 Frankincense Substances 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 244000153234 Hibiscus abelmoschus Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010021750 Infantile Spasms Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010050031 Muscle strain Diseases 0.000 description 1
- 241001057584 Myrrha Species 0.000 description 1
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010058667 Oral toxicity Diseases 0.000 description 1
- LPMXVESGRSUGHW-GHYGWZAOSA-N Ouabain Natural products O([C@@H]1[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O1)[C@H]1C[C@@H](O)[C@@]2(CO)[C@@](O)(C1)CC[C@H]1[C@]3(O)[C@@](C)([C@H](C4=CC(=O)OC4)CC3)C[C@@H](O)[C@H]21 LPMXVESGRSUGHW-GHYGWZAOSA-N 0.000 description 1
- 229930040373 Paraformaldehyde Natural products 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 241000009328 Perro Species 0.000 description 1
- 241000222640 Polyporus Species 0.000 description 1
- 206010038669 Respiratory arrest Diseases 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 241000607762 Shigella flexneri Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 244000166550 Strophanthus gratus Species 0.000 description 1
- 241001279009 Strychnos toxifera Species 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 206010046542 Urinary hesitation Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229940039750 aconitine Drugs 0.000 description 1
- STDXGNLCJACLFY-UHFFFAOYSA-N aconitine Natural products CCN1CC2(COC)C(O)CC(O)C34C5CC6(O)C(OC)C(O)C(OC(=O)C)(C5C6OC(=O)c7ccccc7)C(C(OC)C23)C14 STDXGNLCJACLFY-UHFFFAOYSA-N 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- WDIHJSXYQDMJHN-UHFFFAOYSA-L barium chloride Chemical compound [Cl-].[Cl-].[Ba+2] WDIHJSXYQDMJHN-UHFFFAOYSA-L 0.000 description 1
- 229910001626 barium chloride Inorganic materials 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 1
- 208000036319 cervical spondylosis Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000005660 chlorination reaction Methods 0.000 description 1
- 208000022371 chronic pain syndrome Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000013257 developmental and epileptic encephalopathy Diseases 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical group C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- -1 dredging collateral Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000003677 hemocyte Anatomy 0.000 description 1
- 229940000351 hemocyte Drugs 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 231100000861 limb weakness Toxicity 0.000 description 1
- 208000027905 limb weakness Diseases 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- BCZFSDNVXODRAJ-JTTNIQEDSA-N lycopodine Chemical compound C1CCN2CCC[C@@H]3[C@H]4C[C@@H](C)C[C@]32[C@H]1C(=O)C4 BCZFSDNVXODRAJ-JTTNIQEDSA-N 0.000 description 1
- BCZFSDNVXODRAJ-ZHMBSYLPSA-N lycopodine Natural products C1CCN2CCC[C@@H]3[C@H]4C[C@H](C)C[C@]32[C@H]1C(=O)C4 BCZFSDNVXODRAJ-ZHMBSYLPSA-N 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229940116837 methyleugenol Drugs 0.000 description 1
- PRHTXAOWJQTLBO-UHFFFAOYSA-N methyleugenol Natural products COC1=CC=C(C(C)=C)C=C1OC PRHTXAOWJQTLBO-UHFFFAOYSA-N 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 231100000418 oral toxicity Toxicity 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- LPMXVESGRSUGHW-HBYQJFLCSA-N ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 description 1
- 229960003343 ouabain Drugs 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000003405 preventing effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000003497 sciatic nerve Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 230000016160 smooth muscle contraction Effects 0.000 description 1
- 208000005801 spondylosis Diseases 0.000 description 1
- 229960005453 strychnine Drugs 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 206010048828 underweight Diseases 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses external-use Chinese herbal medicine composition for chronic rheumatism treatment. The composition comprises Chinese herbal medicine raw materials of, by weight: cynanchum mooreanum 40, safflower 20, vegetable sponge of luffa 15, flemingia root 30, notopterygium 15, acorus calamus L 25, Chinese alangium 40, milettia reticulata 15, siegesbeckia 15, rhizoma dioscoreae pipponicae 10, folium clerodendrii 10, asarum herb 10, Chinesestarjasminestem 15, radix aristolochiae 20, herba Lycopodii 30 and ramulus mori 15. External-use Chinese herbal medicine composition for old rheumatism treatment costs low and has good treatment effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, refer in particular to a kind of old rheumatic osteopathia Chinese herbal medicine for external use compositions for the treatment of.
Background technology
As everyone knows, rheumatism, rheumatoid and the painful diseases causing thereof are perplexing the mankind, serious harm people's health even because complication is dead, and be difficult for curing.Existing various liniment and various oral drugs, all have little effect clinically.Existing Western medicine is applied multiple block therapy, or has the medicine that oral toxicity is serious to carry out control pain, but rheumatoid textured bone exists in succession, brings great body and mind painful still to rheumatoid and old chronic pain eloquence.That Chinese patent once disclosed was a kind of " the Traditional Chinese Medicine for external application compositions for the treatment of rheumatic and rheumatoid and chronic pain " (China, publication number CN1682886A, open day on October 19th, 2005), the composition of said composition and parts by weight are: Moschus 3～15, Rhizoma Gastrodiae 10～30, Flos Carthami 12～30, Radix Saposhnikoviae 10～30, Radix Angelicae Pubescentis 10～30, Olibanum 10～30, Herba Menthae 10～18, Myrrha 12～30, Rhizoma Alismatis 12～20, in compositions, also containing total amount is the auxiliary element Cortex Phellodendri of 10～30 parts by weight, Radix Curcumae, Rhizoma Sparganii, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, Polyporus, and available yellow wine is done the use of guiding drug furnishing paste, treatment rheumatic and rheumatoid and various chronic pain disease problem have been solved, there is manufacturing process simple, have no side effect, good effect and the advantage such as be widely used, can make the wind and cold damp-heat syndrome in each joint excrete, treatment rheumatism, rheumatoid disease, cervical spondylosis, lumbar intervertebral disc, scapulohumeral periarthritis, the total effective rate of sweet property sciatica and osteoarthritis is more than 95%.
Summary of the invention
The object of the present invention is to provide a kind of old rheumatic osteopathia Chinese herbal medicine for external use compositions for the treatment of, medical expense is low, and therapeutic effect is good.
For achieving the above object, the present invention takes following technical scheme: a kind ofly treat old rheumatic osteopathia Chinese herbal medicine for external use compositions, each herbal raw material is by weight ratio: cattle 40, Flos Carthami 20, Retinervus Luffae Fructus 15, Radix Flemingiae Philippinensis 30, Rhizoma Et Radix Notopterygii 15, Rhizoma Acori Calami 25, Radix Alangii 40, Caulis Spatholobi 15, Herba Siegesbeckiaes 15, Rhizoma Dioscoreae Nipponicae 10, Folium Clerodendri Trichotomi 10, Herba Asari 10, Caulis Trachelospermi 15, Radix Aristolochiae 20, Herba Lycopodii 30, Ramulus Mori 15 in vain.
The present invention is on the basis of prescription handed down from one's ancestors, and according to clinical practice, the medication tracing observation to patient, constantly adjusts formula, forms above-mentioned Cheng Fang.Its medical expense is low, effective.Each Chinese herbal medicine is easy to get, and consumption is few, and price is low, and external application is convenient, and preservation is easy to carry.
the specific embodiment
Treat a rheumatoid osteopathia Chinese herbal medicine for external use compositions, each herbal raw material proportioning is: cattle 40g, Flos Carthami 20g, Retinervus Luffae Fructus 15g, Radix Flemingiae Philippinensis 30g, Rhizoma Et Radix Notopterygii 15g, water GEPU 25g, Radix Alangii 40g, Caulis Spatholobi 15g, Herba Siegesbeckiae 15g, Rhizoma Dioscoreae Nipponicae 10g, Folium Clerodendri Trichotomi 10g, Herba Asari 10g, Caulis Trachelospermi 15g, Radix Aristolochiae 20g, Herba Lycopodii 30g, Ramulus Mori 15g in vain.
Each Chinese herbal medicine, through science compatibility, is made medicine cake or ointment, spreads on affected part outward, gives full play to their drug effect.Their pharmacology is summarized as follows.
Cattle in vain: for wind-expelling pain-stopping, inducing diuresis to remove edema, rheumatic arthralgia, eczema sore, PARA FORMALDEHYDE PRILLS(91,95) arthritis has antiinflammatory action to a certain degree, and skeletal muscle is had to certain relexation, also has in addition blood pressure lowering, the effect such as anticancer, calm, antibacterial.Flos Carthami: have the effect of expanding blood vessel, can reduce coronary resistance, increase coronary artery blood flow, improve Nutritional myocardium blood flow amount, there are anticoagulation and antithrombotic effect, can excited uterus, low dose makes uterus that rhythmicity occur to shrink, heavy dose makes uterus muscle spasm, can reduce the blood lipid levels such as cholesterol in serum and glycerol vinegar.
Retinervus Luffae Fructus: for dredging collateral, invigorate blood circulation, dispel the wind, arthralgia pain contracture effect, have the meridian dredging also can treat coronary heart disease, have diuresis, increase urine amount, promote uric acid to discharge, also can treat gout, eliminate the phlegm, the effect such as antiinflammatory.
Radix Flemingiae Philippinensis: for wind-damp dispelling, lumbar muscle strain, strong waist knee joint, internal traumatic injury, is used for the treatment of rheumatic arthritis, the effects such as lower limb weakness, chronic lambago and skelalgia.
Rhizoma Et Radix Notopterygii: for anti-inflammatory and antalgic with urge eye effect, even can prevent the convulsion effect of strychnine to the frog, go the effect of wind dehumidifying numbness relieving and pain relieving, the effects such as waist knee joint, arthritis and sciatica.
Rhizoma Acori Calami: the barium chloride arrhythmia of Rhizoma Acori Calami decoct and the anti-rabbit of water solubility extract energy Fructus Citri tangerinae, rat aconitine and the cardiac arrhythmia of Cavia porcellus ouabain are also had to prevention or therapeutical effect, Rhizoma Acori Calami oil, water and alcohol extract, asaricin all has hypotensive effect in animal experiment.Separately there is antitussive, remove expectorant, relieving asthma and the effect such as antibacterial.
Radix Alangii: Radix Alangii containing biology cry out, glucosides, phenols ammonia tomb phenol, organic phenol, heart tonifying symbol and resin etc., Radix Alangii supporting root phenol extraction liquid can strengthen urging the effect of medicament for the eyes, decoct or total alkaloids all can excited breathe but when dosage strengthens respiratory arrest, to normal laboratory animal, can cause blood pressure drops, prolonged application may produce certain influence to liver, kidney merit.
Caulis Spatholobi: for enriching blood, dredging collateral, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia, Caulis Spatholobi decoct has blood tonification effect to the rabbit of experimental anemia, can make its hemocyte increase, hemoglobin raise, decoct is in vitro and in the micro-inhibitory action that is of systemic heart to Bufo siccus, can cause blood pressure drops, can strengthen uterus rhythmicity and receive the effects such as place.
Herba Siegesbeckiae: for wind-damp dispelling, profit joint, extremity arthralgia pain, hemiplegia, removing toxic substances, muscles and bones elementary force, soreness of the waist and knees ， Herba Siegesbeckiae has antiinflammatory action, and the broken animal of fiber crops is had to hypotensive effect, the receipts stagnated blood tube reaction that excites nerve and cause, also has immunosuppressant, antibacterial, analgesia, also can suppress the effects such as thrombosis.
Rhizoma Dioscoreae Nipponicae: for wind-expelling pain-stopping, relaxing muscles and tendons bone, rheumatic arthritis, muscles and bones numbness, traumatic injury, lumbar injury, rheumatic osteopathia, Rhizoma Dioscoreae Nipponicae has antitussive effect, also can reduce Sanguis Leporis seu oryctolagi cholesterol and blood pressure, delay heart rate, strengthen heart receipts place amplitude, increase urine amount, improve the effects such as coronary circulation.
Folium Clerodendri Trichotomi: for rheumatic arthralgia, anesthetized dog or the rat of not anaesthetizing, rabbit, cat, dog and the hypertensive rat of kidney type and dog are all had to hypotensive effect, also have the effects such as significant calmness, analgesia.
Herba Asari: methyleugenol has certain analgesic activity to mice, Herba Asari decoct can reversibly block the conduction of impulse of Toad Sciatic Nerve, and kakuol preserved material can resist the respiration inhibition due to morphine to rabbit vein injection.In addition also have antiinflammatory, improve and breathe, suppress smooth muscle contraction, heart tonifying, shock, lower the temperature, urge eye, antibacterial, regulate the effects such as blood pressure.
Caulis Trachelospermi: for rheumatism pyretic arthralgia, dispelling wind and removing obstruction in the collateral, the contracture of muscle arteries and veins, the detumescence of soreness of waist and knee joint removing heat from blood, traumatic injury effect, have inhibitory action to staphylococcus aureus, shigella flexneri and Bacillus typhi, also can cause the effects such as vasodilation, Blood pressure drop.
Radix Aristolochiae: Radix Aristolochiae is for the breast side of body twinge due to stagnation of liver-QI and stomach-QI, gastral cavity distending pain, colicky, damp-heat diarrhea, internal injury heat-damp in summer and the dysentery stomachache that causes has easing pain and diminishing inflammation effect.
Herba Lycopodii: Herba Lycopodii water logging agent has refrigeration function alcohol extract to have analgesic activity, the sleeping eyes time of energy significant prolongation sodium pentobarbital hypnosis mice, lycopodine is removed infantile spasm urinary hesitancy and constipation etc. to isolated rat.
Ramulus Mori: Mulberry skill skin can make the chlorination materialization of discharging in urine increase and have diuresis, has stronger anti-inflammatory activity, can improve human lymphocyte conversion ratio, has the effect that strengthens immunologic function.
This medicine is treated 379 routine patients, wherein male surname patient 68 examples, female's surname patient 311 examples, 125 examples that have of failing to hold and treating, adhere to 254 examples that have for the treatment of, man's surname adheres to that treatment has 56 examples, women to adhere to 198 examples that have for the treatment of, and healing can reach 100% example, heavy patient cures for 4 months to 6 months, and low weight patient cures for 2 months to 3 months.
Claims (1)
1. the old rheumatic osteopathia Chinese herbal medicine for external use compositions for the treatment of, is characterized in that each herbal raw material is by weight ratio: cattle 40, Flos Carthami 20, Retinervus Luffae Fructus 15, Radix Flemingiae Philippinensis 30, Rhizoma Et Radix Notopterygii 15, Rhizoma Acori Calami 25, Radix Alangii 40, Caulis Spatholobi 15, Herba Siegesbeckiae 15, Rhizoma Dioscoreae Nipponicae 10, Folium Clerodendri Trichotomi 10, Herba Asari 10, Caulis Trachelospermi 15, Radix Aristolochiae 20, Herba Lycopodii 30, Ramulus Mori 15 in vain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210120839.XA CN102626479B (en) | 2012-04-10 | 2012-04-10 | External-use Chinese herbal medicine composition for chronic rheumatism treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210120839.XA CN102626479B (en) | 2012-04-10 | 2012-04-10 | External-use Chinese herbal medicine composition for chronic rheumatism treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102626479A CN102626479A (en) | 2012-08-08 |
| CN102626479B true CN102626479B (en) | 2014-04-09 |
Family
ID=46584987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210120839.XA Expired - Fee Related CN102626479B (en) | 2012-04-10 | 2012-04-10 | External-use Chinese herbal medicine composition for chronic rheumatism treatment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102626479B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893442A (en) * | 2014-04-01 | 2014-07-02 | 周敏 | Traditional Chinese medicine medicament for treating rheumatic arthritis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244252A (en) * | 2008-03-13 | 2008-08-20 | 张金星 | Chinese medicine label for eliminating ache and preparation thereof |
| CN101361923A (en) * | 2008-09-11 | 2009-02-11 | 周功庚 | Traditional Chinese medicine for treating rheumatism |
| CN102293879A (en) * | 2011-09-06 | 2011-12-28 | 陈燕 | Chinese medicinal composition for treating rheumatism |
-
2012
- 2012-04-10 CN CN201210120839.XA patent/CN102626479B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244252A (en) * | 2008-03-13 | 2008-08-20 | 张金星 | Chinese medicine label for eliminating ache and preparation thereof |
| CN101361923A (en) * | 2008-09-11 | 2009-02-11 | 周功庚 | Traditional Chinese medicine for treating rheumatism |
| CN102293879A (en) * | 2011-09-06 | 2011-12-28 | 陈燕 | Chinese medicinal composition for treating rheumatism |
Non-Patent Citations (4)
| Title |
|---|
| 《湖南中医杂志》近年对风湿病报道概况;旷惠桃等;《湖南中医杂志》;20050925;第21卷(第05期);全文 * |
| 徐泽鸿等.类风湿性关节炎临床治疗概述.《时珍国医国药》.1999,第10卷(第12期),全文. |
| 旷惠桃等.《湖南中医杂志》近年对风湿病报道概况.《湖南中医杂志》.2005,第21卷(第05期),全文. |
| 类风湿性关节炎临床治疗概述;徐泽鸿等;《时珍国医国药》;19991210;第10卷(第12期);全文 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102626479A (en) | 2012-08-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103431940A (en) | Health care heating belt with waist and kidney caring function | |
| CN103705751B (en) | Chinese medicine composition being used for the treatment of lumbago due to pathogenic wind-dampness and preparation method thereof | |
| CN102283909B (en) | Medicament for treating anorectal diseases, adiposity, hyperlipemia and acnes and application thereof | |
| CN104258278B (en) | Gushangling (for bone injury) spray | |
| CN105031491A (en) | Tablet for curing malaria and preparation method for tablet | |
| CN104274546A (en) | Externally-applied traditional Chinese medicine composition, externally-applied traditional Chinese medicine preparation as well as preparation method and application of externally-applied traditional Chinese medicine composition | |
| CN101391065B (en) | Compound momordica seed pepper soup for treating urgent chronic pelvic inflammatory disease | |
| CN101376016B (en) | Method for preparing Chinese medicine for treating hyperlipemia | |
| CN102626479B (en) | External-use Chinese herbal medicine composition for chronic rheumatism treatment | |
| CN102895610A (en) | Medicine for treating edema | |
| CN102764360B (en) | Traditional Chinese medicine composition for treating acute cystitis | |
| CN109303811A (en) | The exterior-applied medical wine of activating microcirculation and removing stasis medicinal anti-inflammatory analgetic | |
| CN104784449A (en) | Compounded Tibetan medicine for treating gout, rheumatism, acne, skin diseases and venereal diseases | |
| CN102626477A (en) | Externally used traditional Chinese medicine combination for treating long-time traumatic injury | |
| CN102366597A (en) | Traditional Chinese medicine preparation for prevention and treatment of nervous depression | |
| CN105561270A (en) | Analgesic Chinese herbal medicine for external application and preparation method thereof | |
| CN105561272A (en) | Traditional Chinese medicine preparation for relieving Reynolds disease and preparation method thereof | |
| CN105311210A (en) | Pharmaceutical composition for treating rheumatoid bone diseases | |
| CN105412864A (en) | Pain relieving ointment for treating prolapse of lumbar intervertebral disc | |
| CN103768290A (en) | Traditional Chinese medicine composition for treating synovitis and preparation method thereof | |
| CN103520638B (en) | A kind of Traditional Chinese medicine compound composition for the treatment of prostate hyperplasia and preparation method thereof and application thereof | |
| CN102626491B (en) | Externally used Traditional Chinese medicine composition for treatment of lumbar interveterbral disc protrusion | |
| CN102526544B (en) | Oral powder Chinese medicine formula for treating lumbar disc herniation and osteoproliferation | |
| CN115770279B (en) | Traditional Chinese medicine composition for treating chronic lower limb vein diseases, decoction and preparation thereof | |
| CN101890069A (en) | Medicament for preventing and treating gout and preparation process thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140409 |