CN102283909B - Medicament for treating anorectal diseases, adiposity, hyperlipemia and acnes and application thereof - Google Patents
Medicament for treating anorectal diseases, adiposity, hyperlipemia and acnes and application thereof Download PDFInfo
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Abstract
The invention relates to a medicament for treating anorectal diseases, adiposity, hyperlipemia and acnes. The medicament comprises pharbitis seed, rhubarb and Chinese angelica which serve as active ingredients, has the effects of purging fluid. relieving swelling, promoting blood circulation, removing blood stasis, clearing heat, promoting diuresis, relaxing bowel, detoxifying, relieving pain, cooling blood and stopping bleeding, and can be used for treating anorectal diseases of internal hemorrhoids, external hemorrhoids, mixed hemorrhoids, anal fistula, anal fissure, gastrointestinal polyps, perianal abscess, pruritus ani, pruritus ani, anal eczema, astriction, periproctitis, anal sinusitis, early colorectal cancer, incomplete intestinal obstruction, acute and chronic appendicitis, acute and chronic gastritis, gastroduodenal ulcer and colonitis and also can be used for treating obesity, hyperlipemia, acnes, hyperviscosity, acute urarthritis, gastrointestinal motility caused by after enterocoelia surgery and inflammation caused by anal surgery. Practices prove that the medicament has quick effectiveness, high cure rate, and exact, stable and later treatment effect, addresses both symptoms and root causes, and prevent relapse of the diseases after cure.
Description
Technical field
The invention belongs to tcm field, particularly relate to a kind of medicine and application thereof for the treatment of anal and intestinal disease, obesity, hyperlipemia, acne.
Background technology
Internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, anal fissure, Polyp of gastrointestinal tract, perianal abscess, pruritus ani, anal eczema, constipation, anal inflammation, anal sinusitis, straight colon cancer of initial stage, acute and chronic appendicitis, acute or chronic gastritis, gastroduodenal ulcer, the incomplete ileus, these anal and intestinal diseases of colitis, be clinical common frdquently encountered disease, the traditional Chinese medical science thinks that damp and hot retardance, hematogenous blockage are the main causes that causes the anorectal disease morbidity.
Much fatter finger overnutrition causes body fat to gather too much, causes from be above standard a kind of state of body weight of heavy sensation of the whole body.The fat generation that can cause various diseases is such as hypertension, hyperlipidemia, coronary heart disease, fatty liver, diabetes, cholelithiasis, arthritis etc.
Hyperlipemia be because of blood lipid metabolism get muddled or lipid metabolism and transhipment unusual, a kind of pathological manifestations that causes the lipid material in the blood to exceed normal range.
Chinese medicine anal and intestinal disease, obesity, hyperlipemia have its advantage, because containing Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Stamen Nelumbinis in the component of the present invention, the applicant has retrieved the Chinese medicine patent, find that patent documentation such as the patent No. are 98124804.7 1 kinds of medicines for the treatment of hemorrhoid, anal fistula, formed treatment hemorrhoid, anal fistula by Semen Pharbitidis, Ren sus domestica.
Application number is 02112841.3 1 kinds of Chinese medicinal formulaes that effect a radical cure anal fistula, is made for the treatment of anal fistula Herba Portulacae, Stamen Nelumbinis.
The patent No. is 00107553.5 stomach and kidney disease treating medicine powder, forms treatment acute or chronic gastritis, gastroduodenal ulcer, the incomplete ileus, chronic appendicitis, acute and chronic nephritis, glomerulonephritis, cystitis with Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Radix Rehmanniae Preparata.
The patent No. is 99,115,705 1 kinds of preparation methoies for the treatment of gastritis, gastric ulcer and duodenal ulcer medicine, is made for the treatment of gastritis, gastric ulcer and duodenal ulcer Moschus, Endothelium Corneum Gigeriae Galli, Semen Pharbitidis, Cortex Cinnamomi, Placenta Hominis, furazolidone, vitamin B6.
The patent No. is a kind of hypolipemic medicine for lossing weight of 99124004.9 and preparation method thereof, is combined with oolong tea with Radix Et Rhizoma Rhei, and treatment is fat, hyperlipemia.
Above patent all contains two kinds or several Chinese medicines in Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, the Stamen Nelumbinis, is used for the treatment of anal and intestinal disease, obesity, hyperlipemia, and is evident in efficacy.Prompting uses these diseases of above treatment by Chinese herbs that its strong point is arranged, but above patent is different from overall composition of the present invention, using method, goal of the invention.
The artificial application of application the present invention has consulted a large amount of medical books and patent documentation, the medicine of the treatment anal and intestinal disease of not finding to be made by Semen Pharbitidis, Radix Et Rhizoma Rhei, three kinds of Chinese medicines of Radix Angelicae Sinensis, obesity, hyperlipemia, acne.
Summary of the invention
The object of the invention is to: the medicine that a kind for the treatment of anal and intestinal disease that is comprised of as effective ingredient Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, obesity, hyperlipemia, acne are provided.Also be used for the treatment of high blood viscosity, acute gouty arthritis, obesity complication.And the treatment of abdominal postoperative gastrointestinal motility disorder and anal operation of postop. inflammation, can promote the intestinal peristalsis promoting aerofluxus, reduce intestinal adhesion, diminish inflammation, promote hematoma and absorption of edema, organization healing.
The said medicine that provides of another month of the present invention is being treated internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, anal fissure, Polyp of gastrointestinal tract, perianal abscess, pruritus ani, anal eczema, constipation, anal inflammation, anal sinusitis, straight colon cancer of initial stage, the incomplete ileus, acute and chronic appendicitis, acute or chronic gastritis, gastroduodenal ulcer, colitis anal and intestinal disease, fat, hyperlipemia, acne, high blood viscosity, the application in the acute gouty arthritis.And the application in the treatment of abdominal postoperative gastrointestinal motility disorder and anal operation of postop. inflammation.
The applicant finds that in long-term clinical practice anal and intestinal disease, obesity, hyperlipemia, acne, high blood viscosity, acute gouty arthritis have the pathological manifestations of wet long-pending, diseases caused by retention of fluid, accumulation of phlegm, blood stasis." the senior book series of Chinese medicine---the pharmacology of Chinese medical formulae " P276 points out that diseases caused by retention of fluid, accumulation of phlegm, the stagnation of QI, blood stasis, food stagnation, malnutrition due to parasitic infestation all are applicable to the treatment category of cathartic, and have on dialectical basis or real for heat, or be that water is real, or be expectorant in fact, or be wet long-pending, or all can rationally use purgation for blood stasis.So-called " sick living by heresy, as to have attacked evil disease ".The present invention namely is on the basis of secret prescription handed down in the family from generation to generation, uses Traditional Chinese Medicine to rush down lower prescription and " can promote intestinal tube wriggling and ahead running, reduce capillary permeability, adjust the intestines and stomach and absorb secretory function.The product energy bacteria growing inhibiting of compatibility heat-clearing and toxic substances removing improves immunologic function, degraded toxin, prevention or alleviation toxemia.The compatibility drug for invigorating blood circulation and eliminating stasis can improve the local blood microcirculation, changes the hemorheology state, and reaction reduces inflammation " theory and combining modern pharmacology achievement in research, choose the medicine that Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis are prepared from as effective ingredient, genus traditional Chinese medical science cathartic.
The present invention realizes like this, it is comprised of as effective ingredient Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis, for improving therapeutic effect, can also add Stamen Nelumbinis as effective ingredient, its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis, 1～4 part of Stamen Nelumbinis.
In this medicine, Semen Pharbitidis: hardship, cold.Return large intestine, lung, kidney channel.Have the detumescent of relieving oedema or abdominal distension through diuresis or purgation and rush down drink, capture stagnant, diuresis, the effect of ascarifuge.Modern pharmacological research thinks, this product can stimulate intestinal, promotes wriggling, causes acutely rushing down lower.
Radix Et Rhizoma Rhei: hardship, cold.Return large intestine, spleen, stomach, the heart, Liver Channel.Have and rush down lower stagnating, clearing away heat-fire, cooling blood for hemostasis, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling rushes down clearly damp and hot effect.Modern pharmacological research thinks, this product can strengthen intestinal peristalsis and promote defecation, and does not hinder small intestinal to the absorption of nutrient substance; By central nervous system's impact, the effects such as analgesic, analgesia, antiinflammatory are arranged; To cardiovascular system blood pressure lowering arranged, improve microcirculation, the effect such as blood fat reducing, reduction serum total cholesterol; Urinary system there are diuresis and the drainage that promotes carbamide, creatinine, improve the effects such as renal function; Also have that hemostasis, antithrombotic form, the anti-experimental character gastric ulcer forms, protect the liver, function of gallbladder promoting, antibacterial and suppress the effect of gastric emptying, inhibition stomach egg enzyme.
Radix Angelicae Sinensis: sweet, hot, temperature.Return liver, the heart, large intestine channel.Have and enrich blood, invigorate blood circulation, pain relieving, regulating menstruation, the effect of loosening bowel to relieve constipation.Modern pharmacological research thinks, Radix Angelicae Sinensis can significantly promote hemoglobin and erythrocytic generation, and laboratory animal leukocyte and reticulocyte are increased; Can expand peripheral blood vessel, alleviate the peripheral blood vessel smooth muscle spasm, increase blood flow, improve peripheral circulation; The platelet aggregation of reduction and anti thrombotic action are arranged; Antiinflammatory, analgesic activity are arranged; Non-specific and specific immune function there is potentiation; Hepatoprotective effect is arranged, can prevent that liver glycogen from reducing, promote liver cell regeneration and recover some function of liver; Antitumor, antibacterial action are arranged.Below all select from China Traditional Chinese Medicine Publishing House's version " Chinese materia medica () " in 2000
All medicines share the effect of playing altogether the detumescence of relieving oedema or abdominal distension through diuresis or purgation, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, loosening bowel to relieve constipation, detoxifcation pain relieving, cooling blood for hemostasis, thereby reach the healing purpose.Said medicine can be used for treating internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, anal fissure, Polyp of gastrointestinal tract, perianal abscess, pruritus ani, anal eczema, constipation, anal inflammation, anal sinusitis, straight colon cancer of initial stage, the incomplete ileus, acute and chronic appendicitis, acute or chronic gastritis, gastroduodenal ulcer, colitis anal and intestinal disease, fat, hyperlipemia, acne, high blood viscosity, acute gouty arthritis, instant effect, treating both the principal and secondary aspects of a disease does not recur after healing.Also can be used for the treatment of abdominal postoperative gastrointestinal motility disorder and anal operation of postop. inflammation.
Stamen Nelumbinis: sweet, puckery, flat.GUIXIN, kidney channel.Clear away heart-fire kidney tonifying, arresting seminal emission, hemostasis.Cure mainly the nocturnal emission lingering diarrhea, metrorrhagia is spitted blood, and has loose bowels dysentery.Stamen Nelumbinis is joined HEIQIANNIU: astringent or styptic treatment for spontaneous sweating leak-stopping is arranged, the capable water of invigorating blood circulation, the effect that nourishes blood and clear away heart-fire.With controlling new and old anal fistula, anal fissure person." modern clinic Chinese materia medica " P781 in 2002 that selects from publishing house of Shanghai Univ. of Traditional Chinese Medicine.Modern pharmacology thinks that Stamen Nelumbinis has whitening, antithrombotic, and analgesia, antiulcer is controlled the diarrhoea effect." Stamen Nelumbinis Medicinal Study Development " Strait Pharmaceutical Journal the 18th volume in 2006 the 4th phase P20.
Internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, anal fissure, Polyp of gastrointestinal tract, perianal abscess, pruritus ani, anal eczema, constipation, anal inflammation, anal sinusitis, straight colon cancer of initial stage, the incomplete ileus, acute and chronic appendicitis, acute or chronic gastritis, gastroduodenal ulcer, these anal and intestinal diseases of colitis, the traditional Chinese medical science thinks that internal organs are weak, have a cold outward, interior intrinsic heat poison, or eating and drinking without temperance, production of dryness-heat in the interior, the QI and blood knot stagnates, gastrointestinal, anal canal are corroded in damp and hot tenesmus, formation slough blood stasis etc. causes, its cause of disease mostly is Accumulation of Dampness Heat and Blood Stasis, also has due to the deficiency of vital energy, but still has damp and hot resembling.The Accumulation of Dampness Heat and Blood Stasis of system, QI and blood retardance, hematogenous blockage are the main causes that causes the anal and intestinal disease morbidity.The present invention treats anal and intestinal disease and captures stagnantly with Semen Pharbitidis, and the detumescent of relieving oedema or abdominal distension through diuresis or purgation is rushed down drink, rushed down lower turbid damp, improves the anorectal metabolism; Because anal and intestinal disease has blood stasis, damp and hot sign more, with the Radix Et Rhizoma Rhei cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, clear sharp intestinal is damp and hot simultaneously, suppresses thrombosis, improves local microcirculation, anti-inflammatory and antalgic; Most anal and intestinal disease patients are hard and dry in addition, just after an action of the bowels hemorrhage or the symptom of stool blood and the sign of hematogenous blockage before, have blood in stool for a long time and cause self anemia, with Chinese angelica blood supplementing invigorate blood circulation, moistening dryness for relaxing bowels, pain relieving, improve simultaneously peripheral circulation, antiinflammatory, reduction platelet aggregation and antithrombotic form, thereby reach the purpose of curing anal and intestinal disease.The Stamen Nelumbinis that is aided with nourshing blood and promoting blood circulation, promoting the production of body fluid to quench thirst, hemostasis strengthens antithrombotic, analgesia, antiulcer action, improves cure rate.
The traditional Chinese medical science thinks that obesity, hyperlipemia, acne, high blood viscosity, acute gouty arthritis result from " expectorant, wet, the stasis of blood, heat ", how be obstructed because of the intestines and stomach zang-fu organs qi movement, cold-phlegm, water are wet, stop in the pathogenic fluid-retention, the interior heap soil or fertilizer over and around the roots in gastral cavity abdomen channel tunnel, the heresy of damp-phlegm muddy water must not be descending, causes the internal metabolism disorder to cause.Prescriptions Worth Thousand Gold for Emergencies has " all internal organs gather, and without asking the youthful and the elderly, need rush down then and rush down ", and the present invention had both followed the six hollow viscera must keep its unobstructed, and logical for gastrointestinal is the theory of benefit, rushes down drink, rushes down lower cold-phlegm turbid damp with the Semen Pharbitidis detumescent of relieving oedema or abdominal distension through diuresis or purgation.Retention of phlegm hydrops Su Gujian abdominal mass under " beautiful Chinese catalpa medicine solution " Semen Pharbitidis, parasite killing rushes down legendary venomous insect, except swollen relieving distension, the difficult unination symptom-complex constipation, the disease of winddorn freckle is all cured.Push away Chen Zhixin, rush down damp and hot, removing pathogenic heat from blood and toxic substance from the body clearly with Radix Et Rhizoma Rhei, and Radix Et Rhizoma Rhei is heavy dose of with get rid of illness the thick the intestines and stomach of low dose of usefulness energy for attacking heresy; Be aided with that Chinese angelica blood supplementing is invigorated blood circulation, blood stasis dispelling, relieving constipation, pain relieving, thereby reach the purpose for the treatment of obesity, hyperlipemia, acne, high blood viscosity, acute gouty arthritis.Wherein, Radix Et Rhizoma Rhei is fat for treatment, hyperlipemia, the active drug of acne (" the senior book series-pharmacology of Chinese materia medica of Chinese medicine " P334-P337), modern pharmacology confirms that Radix Et Rhizoma Rhei has the heart tonifying blood pressure lowering, blood fat reducing, the hepatoprotective function of gallbladder promoting, the effects such as blood sugar lowering, therefore, the present invention can treat the syndrome that obesity causes simultaneously, yet alone Radix Et Rhizoma Rhei easily causes the secondary constipation, and Drug resistance can appear in the prolonged application Radix Et Rhizoma Rhei, lessen the curative effect, this has limited the application of Radix Et Rhizoma Rhei, the present invention is with Semen Pharbitidis, Radix Angelicae Sinensis and Radix Et Rhizoma Rhei compatibility, solve the shortcoming of alone Radix Et Rhizoma Rhei, improved the effect for the treatment of above disease, be aided with again black beard and hair, improving healthy complexion, benefit blood, controlling nocturnal emission with astringent drugs, clear away heart-fire and reinforce the kidney, the Stamen Nelumbinis of promoting the production of body fluid to quench thirst (Shanghai science tech publishing house " Chinese medicine voluminous dictionary "), the tonification kidney, making has benefit in rushing down, let out turbid controlling nocturnal emission with astringent drugs, alleviate simultaneously and eliminate because of Semen Pharbitidis, the stomachache that Radix Et Rhizoma Rhei causes, diarrhoea further strengthens the kidney separating clear and excreting turbid, arrange turbid power, turbid going and just not hindering makes curative effect more remarkable.
Take the patient who has behind the present invention and stomachache, diarrhoea or bloody purulent stool can occur, it is purplish red, tangerine or orange red that urine becomes, and is normal phenomenon, and this is the removing blood stasis toxin expelling, can not have side effects, and does not also have the sequela shape, can relievedly use.
The invention has the beneficial effects as follows instant effect, expense is low, cure rate is high, determined curative effect is stable lasting, medicine is easy to get, the medicine source is sufficient, low, the easy preparation of cost.Beneficial effect of the present invention also is Orally taken and externally, smokes to wash demibain, and the administration of coloclysis suppository number of ways all can be used.
The specific embodiment
By the following examples, the present invention is described in further detail, embodiment only is indicative, the present invention includes but be not limited to following examples, also never mean it by any way or form limit the scope of the invention, do not breaking away under the technology of the present invention state of mind, the various replacements of making according to ordinary skill knowledge and habitual means or the modification of change include within the scope of the invention.
The medicine for the treatment of anal and intestinal disease, obesity, hyperlipemia, acne, by Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis as effective ingredient.Its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis.
Embodiment 1 Semen Pharbitidis 1 gram, Radix Et Rhizoma Rhei 5 grams, Radix Angelicae Sinensis 1 gram.Make honeyed pill by the pharmaceutics conventional method.
Embodiment 2 Semen Pharbitidiss 6 grams, Radix Et Rhizoma Rhei 5 grams, Radix Angelicae Sinensis 5 grams.Make suppository by the pharmaceutics conventional method.
Embodiment 3 Semen Pharbitidiss 1 gram, Radix Et Rhizoma Rhei 5 grams, Radix Angelicae Sinensis 5 grams.Make powder by the pharmaceutics conventional method.
Embodiment 4 Semen Pharbitidiss 6 grams, Radix Et Rhizoma Rhei 1 gram, Radix Angelicae Sinensis 1 gram.Make capsule by the pharmaceutics conventional method.
Embodiment 5 Semen Pharbitidiss 9 grams, Radix Et Rhizoma Rhei 6 grams, Radix Angelicae Sinensis 3 grams.Make the watered pill or wine ball by the pharmaceutics conventional method.
For improving therapeutic effect, can also add Stamen Nelumbinis as effective ingredient.Its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis, 1～4 part of Stamen Nelumbinis.
Embodiment 6 Semen Pharbitidiss 6 grams, Radix Et Rhizoma Rhei 5 grams, Radix Angelicae Sinensis 5 grams, Stamen Nelumbinis 4 grams.Make capsule by the pharmaceutics conventional method.
Embodiment 7 Semen Pharbitidiss 6 grams, Radix Et Rhizoma Rhei 4 grams, Radix Angelicae Sinensis 4 grams, Stamen Nelumbinis 3 grams.Make powder by the pharmaceutics conventional method.
Embodiment 8 Semen Pharbitidiss 3 grams, Radix Et Rhizoma Rhei 5 grams, Radix Angelicae Sinensis 2 grams, Stamen Nelumbinis 2 grams.Make suppository by the pharmaceutics conventional method.
Embodiment 9 Semen Pharbitidiss 40 grams, Radix Et Rhizoma Rhei 20 grams, Radix Angelicae Sinensis 10 grams, Stamen Nelumbinis 10 grams.Make honeyed pill by practice of pharmacy.
Embodiment 10 Semen Pharbitidiss 9 grams, Radix Et Rhizoma Rhei 9 grams, Radix Angelicae Sinensis 9 grams, Stamen Nelumbinis 9 grams.Make the wine ball by the pharmaceutics conventional method.
Above each embodiment includes but not limited to described dosage form, except making the corresponding dosage form by described method, also can make any various dosage forms that are suitable for clinical needs by the pharmaceutics conventional method.
The present invention is through the checkings of applicant's more than ten years proof treatment anal and intestinal disease, obesity, hyperlipemia, acne, acute gouty arthritis definite effect, especially belongs to damp and hot stasis person to dialectical, and effect is more remarkable.For proving advantage of the present invention, further set forth application of the present invention and beneficial effect according to embodiment and clinical observation on the therapeutic effect.
Clinical verification: following all cases are applicant's clinic case
One. physical data and diagnostic criteria and Therapeutic Method
Diagnostic criteria: all with reference to People's Health Publisher Weng Weiliang chief editor " Chinese medicine clinical pharmacology " and dependent diagnostic standard.
1. hemorrhoid 68 examples, internal hemorrhoid 21 examples wherein, external hemorrhoid 13 examples, mixed hemorrhoid 34 examples.Hemorrhoid companion pruritus ani 12 examples, companion's anal fissure 20 examples.Anal fissure 52 examples, perianal abscess 7 examples, anal fistula 4 examples, rectal polyp 14 examples, polyp of stomach 4 examples, pruritus ani, eczema 13 examples.Acute and chronic appendicitis is totally 18 examples, constipation 110 examples, anal inflammation 5 examples, anal sinusitis 8 examples, each 2 example of straight colon cancer of initial stage, the incomplete ileus 4 examples, colitis 32 examples.Acute gastritis 11 examples, chronic gastritis 34 examples.Gastroduodenal ulcer 23 examples.
Therapeutic Method: oral powder, wine ball, honeyed pill or capsule are each serving 5～12 grams, and every day 1～3 time is with Chinese liquor or water delivery service.The podex disease is except oral medicine, separately or be used in conjunction with suppository every day 2 times; Or transfer powder to be coated with affected part every day 2～3 times outward with Oleum sesami, vinegar, or with boiling water break up agent smoked first after demibain affected part 30 minute every day 2～3 times.10 days is a course for the treatment of.Gastrointestinal disease is except oral medicine, separately or be used in conjunction with abdomen external application powder, or with the retention enema of water logging medicine filtering residue.10 days is a course for the treatment of.
2. acne 29 examples.Therapeutic Method: each 5～10 grams of powder, wine ball or capsule, every day 2～3 times, boiled water takes, and cooperates Mel or Ovum Gallus domesticus album to transfer powder external application affected part, 1 time every night, morning flush away.15 days is a course for the treatment of.
3. obese patient's 51 examples, 15～58 years old age, 19 of male, 32 of women, wherein, with high blood viscosity person 9 examples, with hyperlipemia person's 6 examples.
Therapeutic Method: each 2 balls of honeyed pill, sooner or later respectively take 1 time, boiled water takes; And in the situation that the patient is voluntary with water or vaseline accent powder 5～10 gram external application umbilicuss, every day 2 times, 20 days is a course for the treatment of.Or transfer powder 25～35 gram external application umbilicuss to reach on every side 1 time every night with water separately, each 6～10 hours, 1 month was 1 course for the treatment of.
4. acute gouty arthritis 15 routine patients, male 13 examples wherein, women 2 examples, ill 1 month～10 years.
Therapeutic Method: powder, wine pill or capsule take every day 2～3 times each serving 7～10 grams with Chinese liquor or boiled water; And cooperate boiling water to break up agent dipping bath affected part 30 minutes, every day 2～4 times.Or separately with Chinese liquor, vinegar or the coated affected part of the water amount of adjusting powder, changed dressings once in per 8～12 hours.7 days is a course for the treatment of.
5. hyperlipemia, high blood viscosity: patient's 34 examples, male 24 examples wherein, women 10 examples.
Therapeutic Method: each 2 balls of honeyed pill, respectively take 1 time every day sooner or later, and boiled water takes; And cooperate with Oleum sesami (water or vaseline also can) and transfer powder external application umbilicus place, every day 1 time, each 3～10 grams.20 days is a course for the treatment of.
Two. criterion of therapeutical effect and therapeutic outcome
Criterion of therapeutical effect is all formulated with reference to People's Health Publisher Weng Weiliang chief editor " Chinese medicine clinical pharmacology " and in conjunction with practical situation.
Cure: clinical symptoms, sign disappear, and follow up a case by regular visits to not recurrence more than 1 year after the healing.Effectively: clinical symptoms, sign are improved, and still idol is used the medicine effector.Invalid: clinical symptoms, sign are without improving or worsening.
1. hemorrhoid 68 examples, anal fissure 52 examples, perianal abscess 7 examples, pruritus ani, eczema 13 examples, anal inflammation 5 examples, anal sinusitis 8 examples, the incomplete ileus 4 examples, constipation 110 examples, colitis 32 examples are all cured through 1～4 course of therapy.
Anal fistula 4 examples, rectal polyp 14 examples, polyp of stomach 4 examples, acute and chronic appendicitis 18 examples, acute gastritis 11 examples, chronic gastritis 34 examples, gastroduodenal ulcer 23 examples.All cure through 2～5 course of therapy.
Each 2 example of straight colon cancer of initial stage are cured each 1 example through 2～5 course of therapy, effectively each 1 example.
2. acne is cured 24 examples through 1～3 course of therapy, effective 4 examples, invalid 1 example.
3. fat of 1～2 course of therapy, cure 47 examples, effective 3 examples, invalid 1 example.
4. acute gouty arthritis is cured 11 examples through 1～2 course of therapy, effective 3 examples, invalid 1 example.
5. hyperlipemia, high blood viscosity is cured 29 examples through 1～2 course of therapy, effective 4 examples, invalid 1 example.
Claims (3)
1. the medicine for the treatment of anal and intestinal disease, obesity, hyperlipemia, acne is characterized in that by Semen Pharbitidis, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis as effective ingredient, its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis.
2. medicine according to claim 1 is characterized in that also adding Stamen Nelumbinis as effective ingredient, and its weight portion is 1～6 part of Semen Pharbitidis, 1～5 part of Radix Et Rhizoma Rhei, 1～5 part of Radix Angelicae Sinensis, 1～4 part of Stamen Nelumbinis.
3. the application of medicine according to claim 1 and 2 in preparation treatment internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, anal fissure, Polyp of gastrointestinal tract, perianal abscess, pruritus ani, anal eczema, constipation, anal inflammation, anal sinusitis, straight colon cancer of initial stage, the incomplete ileus, acute and chronic appendicitis, acute or chronic gastritis, gastroduodenal ulcer, colitis medicine reaches in the preparation treatment fat, hyperlipemia, acne, high blood viscosity, acute gouty arthritis, the application in the medicine of abdominal postoperative gastrointestinal motility disorder and anal operation of postop. inflammation.
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| CN102648962A (en) * | 2012-04-20 | 2012-08-29 | 苏州爱斯欧蒂生物科技有限公司 | Medicine for treating gastrointestinal diseases |
| CN103920121A (en) * | 2014-04-21 | 2014-07-16 | 郑家林 | Traditional Chinese medicine wine for coordinating intestines and stomach and treating constipation |
| CN104095902A (en) * | 2014-08-08 | 2014-10-15 | 闫山峰 | Traditional Chinese medicine composition for removing food retention and helping to digest |
| CN110833578A (en) * | 2018-08-16 | 2020-02-25 | 中国中医科学院望京医院 | Traditional Chinese medicine composition for treating and/or preventing intestinal polyp recurrence |
| CN110812405A (en) * | 2019-12-18 | 2020-02-21 | 河南中医药大学 | Citrus aurantium flower essential oil for treating functional constipation |
| CN111053829A (en) * | 2020-01-20 | 2020-04-24 | 广东药科大学 | Traditional Chinese medicine composition for treating abdominal obesity and preparation and external preparation thereof |
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