CN108064161A - A kind of burn and scald spray that the surface of a wound is promoted quickly to heal - Google Patents

A kind of burn and scald spray that the surface of a wound is promoted quickly to heal Download PDF

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Publication number
CN108064161A
CN108064161A CN201780001789.4A CN201780001789A CN108064161A CN 108064161 A CN108064161 A CN 108064161A CN 201780001789 A CN201780001789 A CN 201780001789A CN 108064161 A CN108064161 A CN 108064161A
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China
Prior art keywords
wound
parts
burn
heal
scald
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Pending
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CN201780001789.4A
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Chinese (zh)
Inventor
吴克
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Publication of CN108064161A publication Critical patent/CN108064161A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/49Fagaceae (Beech family), e.g. oak or chestnut
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015Drug-containing film-forming compositions, e.g. spray-on

Abstract

This case discloses a kind of burn and scald spray that the surface of a wound is promoted quickly to heal, and includes the material component of following parts by weight:5 15 parts of orange peel;5 10 parts of withy skin;Mostly according to 39 parts;39 parts of eucalyptus robusta;27 parts of chestnut leaves;15 parts of white melitot;13 parts of the shell of seaear;0.5 2.2 parts of calcined oyster shell;0.2 1.8 parts of black soybean oil;12 parts of corn bran.The burn and scald spray provided by the invention that the surface of a wound is promoted quickly to heal can be sprayed onto empyrosis wound surface rapid film formation, the production of wound tissue new capillary vessel can be remarkably promoted, reduce the secondary infection of the surface of a wound, and it avoids and directly smears secondary injury or bacterium infection caused by wound face, wound healing time is fast, and scar inhibition is apparent.

Description

A kind of burn and scald spray that the surface of a wound is promoted quickly to heal
Technical field
The invention belongs to the field of Chinese medicines, are related to a kind of medicinal herb spray and preparation method thereof, more particularly to a kind of promotion The burn and scald spray that the surface of a wound quickly heals.
Background technology
Burn and scald is clinical common wound, refers to since heating power is damaged caused by tissue, common are flame Scald caused by burn and hydrothermal solution.Some non-thermodynamics factors such as electricity, chemical substance, ray can also make tissue by similar The damage of burn.The treatment of burn wound and agglutination are complicated, and the time is longer, and scar contracture and work(can be left after wound healing The sequelae such as energy obstacle.
Modern medicine study thinks, wound healing is to organize missing caused by body repairs various damages, by regeneration and The means such as reparation, to recover the process of body tissue structure and functional completeness.The basis for smoothly completing agglutination is a variety of The normal performance of healing relevant cell biological function, and dependent cells, extracellular matrix and growth factor and cell factor exist Interaction between interior soluble mediators.In existing curing burn and scald object, although the treatment technology of doctor trained in Western medicine exists always Update, but since its mechanism of action is single, in long therapeutic procedure, therapeutic effect is bad always.Due to burn and scald illness into Because of complexity, mechanistic nature is changeable, and important advantages are notable, and has achieved significant breakthrough, but there are each component compatibility not Very rationally, treatment time is long, and curative effect is slow and mostly plaster dosage form, directly smearing easily cause surface of a wound injury, cause superinfection The problems such as.
The content of the invention
Part against the above deficiency, it is an object of the invention to provide a kind of burn and scald that the surface of a wound is promoted quickly to heal sprayings Agent can be sprayed onto empyrosis wound surface rapid film formation, can remarkably promote the production of wound tissue new capillary vessel, reduce the surface of a wound after The sexy dye of hair, and avoid and directly smear secondary injury or bacterium infection caused by wound face, wound healing time is fast, scar Inhibition is apparent.
Technical scheme is summarized as follows:
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:
In above-mentioned burn and scald sprayer formulation, orange peel, withy skin and Duo Yi are altogether monarch drug in a prescription, have disinfection, infection control With the effect of dredging surface of a wound part train of thought blood vessel;Eucalyptus robusta, chestnut leaves, white melitot and the shell of seaear are altogether ministerial drug, have myogenic, delay Solve the effect of empyrosis wound surface feeling of pain;Calcined oyster shell is adjutant, plays an important role of convergence detumescence;Black soybean oil and corn bran are to make altogether Medicine can form one layer of protective film in empyrosis wound surface, beneficial to drug absorption, and controllable skin lesion and inflammation.
Preferably, wherein, it is filling after the material component is crushed into powder, then after alcohol dipping, extraction and filtering To burn and scald spray formulation.
Preferably, wherein, the burn and scald spray formulation contains the ethyl alcohol of 80-85wt%, under this concentration of alcohol, system Standby obtained spray formulation stability highest.
Preferably, wherein, the first and second aldehyde of polyvinyl alcohol ester of 2-3wt% is further included in the burn and scald spray formulation, it can Significantly shorten film formation time, increase drugloading rate, promote the performance of medicinal herb components.
Preferably, wherein, the glycerine of 0.7-1.2wt%, the addition of glycerine are further included in the burn and scald spray formulation The stability of film forming is can further improve, beneficial to the recovery of empyrosis wound surface.
Preferably, wherein, the grain size of the powder is 100~500 μm, described to be extracted as Dynamic Extraction, in the application In file, the grain size of raw material powder need not be too thin, and grain size is 100~500 μm of extractions that active ingredient can be realized, and is not only dropped Low crushing cost, it is thus also avoided that the Dynamic Extraction hypertonia brought because powder is meticulous.
Preferably, wherein, Dynamic Extraction, active ingredient dissolution rate are carried out to the powder using the ethyl alcohol of 90wt% Soon, dissolution efficiency is high.
Preferably, wherein, during the Dynamic Extraction, the ethyl alcohol of the 90wt% is the 5~8 of powder volume Times, to ensure the abundant extraction of effective component of chinese medicine.
The beneficial effects of the invention are as follows:The burn and scald spray provided by the invention that the surface of a wound is promoted quickly to heal, can be significantly Shorten the time of wound healing, healing rate is high, and can effectively prevent the surface of a wound from forming scar.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, to make those skilled in the art with reference to specification Word can be implemented according to this.
Embodiment 1
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:Orange peel 5 Part;5 parts of withy skin;Mostly according to 3 parts;3 parts of eucalyptus robusta;2 parts of chestnut leaves;1 part of white melitot;1 part of the shell of seaear;0.5 part of calcined oyster shell;Black soya bean 0.2 part of oil;1 part of corn bran.
Above-mentioned raw materials component is taken to be ground into the powder that grain size is 100 μm, then after alcohol dipping, Dynamic Extraction and filtering, is filled Dress obtains burn and scald spray formulation, the ethyl alcohol that the burn and scald spray formulation being prepared contains 80wt%.
Wherein, in above-mentioned preparation scheme, Dynamic Extraction, the second of 90wt% are carried out to the powder using the ethyl alcohol of 90wt% Alcohol is 5 times of powder volume.
Wherein, polyvinyl alcohol ester first and second aldehyde and 0.7wt% of the burn and scald spray formulation being prepared also containing 2wt% Glycerine.
Embodiment 2
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:Orange peel 15 Part;10 parts of withy skin;Mostly according to 9 parts;9 parts of eucalyptus robusta;7 parts of chestnut leaves;5 parts of white melitot;3 parts of the shell of seaear;2.2 parts of calcined oyster shell;It is black 1.8 parts of soya-bean oil;2 parts of corn bran.
It is 500 μm of powder that above-mentioned raw materials component is taken, which to be ground into grain size, then after alcohol dipping, Dynamic Extraction and filtering it is filling Burn and scald spray formulation is obtained, the ethyl alcohol that the burn and scald spray formulation being prepared contains 85wt%.
Wherein, in above-mentioned preparation scheme, Dynamic Extraction, the second of 90wt% are carried out to the powder using the ethyl alcohol of 90wt% Alcohol is 8 times of powder volume.
Wherein, polyvinyl alcohol ester first and second aldehyde and 1.2wt% of the burn and scald spray formulation being prepared also containing 3wt% Glycerine.
Embodiment 3
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:Orange peel 10 Part;7 parts of withy skin;Mostly according to 6 parts;5 parts of eucalyptus robusta;5 parts of chestnut leaves;3 parts of white melitot;2 parts of the shell of seaear;1.5 parts of calcined oyster shell;Black soya bean 1 part of oil;1.5 parts of corn bran.
It is 300 μm of powder that above-mentioned raw materials component is taken, which to be ground into grain size, then after alcohol dipping, Dynamic Extraction and filtering it is filling Burn and scald spray formulation is obtained, the ethyl alcohol that the burn and scald spray formulation being prepared contains 83wt%.
Wherein, in above-mentioned preparation scheme, Dynamic Extraction, the second of 90wt% are carried out to the powder using the ethyl alcohol of 90wt% Alcohol is 7 times of powder volume.
Wherein, polyvinyl alcohol ester first and second aldehyde and 1.0wt% of the burn and scald spray formulation being prepared also containing 2.5wt% Glycerine.
Embodiment 4
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:Orange peel 7 Part;7 parts of withy skin;Mostly according to 8 parts;8 parts of eucalyptus robusta;3 parts of chestnut leaves;2 parts of white melitot;1.5 parts of the shell of seaear;2 parts of calcined oyster shell;Black soya bean 1.5 parts of oil;1.8 parts of corn bran.
It is 200 μm of powder that above-mentioned raw materials component is taken, which to be ground into grain size, then after alcohol dipping, Dynamic Extraction and filtering it is filling Burn and scald spray formulation is obtained, the ethyl alcohol that the burn and scald spray formulation being prepared contains 82wt%.
Wherein, in above-mentioned preparation scheme, Dynamic Extraction, the second of 90wt% are carried out to the powder using the ethyl alcohol of 90wt% Alcohol is 6 times of powder volume.
Wherein, polyvinyl alcohol ester first and second aldehyde and 0.8wt% of the burn and scald spray formulation being prepared also containing 2.2wt% Glycerine.
Embodiment 5
A kind of burn and scald spray that the surface of a wound is promoted quickly to heal includes the material component of following parts by weight:Orange peel 12 Part;9 parts of withy skin;Mostly according to 4 parts;4 parts of eucalyptus robusta;6 parts of chestnut leaves;4 parts of white melitot;2.5 parts of the shell of seaear;0.7 part of calcined oyster shell;It is black 0.4 part of soya-bean oil;1.2 parts of corn bran.
It is 400 μm of powder that above-mentioned raw materials component is taken, which to be ground into grain size, then after alcohol dipping, Dynamic Extraction and filtering it is filling Burn and scald spray formulation is obtained, the ethyl alcohol that the burn and scald spray formulation being prepared contains 84wt%.
Wherein, in above-mentioned preparation scheme, Dynamic Extraction, the second of 90wt% are carried out to the powder using the ethyl alcohol of 90wt% Alcohol is 7 times of powder volume.
Wherein, polyvinyl alcohol ester first and second aldehyde and 1.1wt% of the burn and scald spray formulation being prepared also containing 2.7wt% Glycerine.
In order to illustrate the effect of the present invention, it is as follows that inventor provides comparative experiments:
<Comparative example 1>
When preparing burn and scald spray, do not add the first and second aldehyde of corn bran and polyvinyl alcohol ester, remaining parameter in example 1 It is identical, technical process is also identical.
<Comparative example 2>
When preparing burn and scald spray, the first and second aldehyde of polyvinyl alcohol ester, remaining parameter and the complete phase in example 1 are not added Together, technical process is also identical.
<Comparative example 3>
When preparing burn and scald spray, glycerine is not added, remaining parameter is with identical in example 2, technical process Also it is identical.
<Comparative example 4>
When preparing burn and scald spray, withy skin is not added, remaining parameter is with identical in example 3, technique mistake Journey is also identical.
Therapeutic test is carried out using examples detailed above and comparative example to deepⅱdegreeburn rat model:
45 deepⅱdegreeburn rat models are chosen, are randomly divided into 9 groups, are respectively adopted prepared by examples detailed above and comparative example After scald spray administration, the substantially change of the surface of a wound is observed, and calculates Wound healing rate,
Wherein, the computational methods of wound healing situation rate:The situation for judging wound healing is traced using hyaline membrane.It is specific public It is shown as:Do not heal Wound healing rate=(original surface of a wound area-area) * 100%/original surface of a wound area.Concrete outcome is referring to table 1 With table 2.
1 each example of table and comparative example are to the treatment results of deepⅱdegreeburn rat model
1 each example of table and comparative example count the wound infection rate after deepⅱdegreeburn rat model medication
Trauma surface infestation number of cases (only)
Example 1 0
Example 2 0
Example 3 0
Example 4 0
Example 5 0
Comparative example 1 5
Comparative example 2 3
Comparative example 3 1
Comparative example 4 2
Comparative example 1 does not add the first and second aldehyde of corn bran and polyvinyl alcohol ester compared with example, in burn and scald sprayer formulation, gives After deepⅱdegreeburn rat medication 3-6 days, there is infection liquefaction phenomenon in the surface of a wound, this illustrates corn bran and polyvinyl alcohol ester first and second The addition of aldehyde by filming function, can give full play to the effect of the protection surface of a wound.
Comparative example 2 does not add the first and second aldehyde of polyvinyl alcohol ester compared with example, in burn and scald sprayer formulation, to deep II degree of burning After hindering rat medication 7 days, also there is infection liquefaction phenomenon in the surface of a wound of partial rat, this illustrates the addition of the first and second aldehyde of polyvinyl alcohol ester The protective effect to the surface of a wound can be dramatically increased.
Comparative example 3 does not add glycerine compared with example in burn and scald sprayer formulation, gives deepⅱdegreeburn rat medication Afterwards, also there is infection liquefaction phenomenon in the surface of a wound of the rat of a small amount of ratio, this illustrates that the addition of glycerine can increase the protection to the surface of a wound Effect, and the addition of glycerine can improve the stability that burn and scald spray is placed for a long time, beneficial to burn and scald spray drug effect It plays.
Comparative example 4 does not add withy skin compared with example in burn and scald sprayer formulation, give deepⅱdegreeburn rat medication Afterwards, also there is infection liquefaction phenomenon in the surface of a wound of partial rat, this illustrates that the addition of withy skin has significant disinfection and Perceived control The effect of dye.
As it can be seen that the burn and scald spray provided by the invention that the surface of a wound is promoted quickly to heal, can significantly shorten wound healing Time, healing rate is high, and can effectively prevent the surface of a wound from forming scar.
Although the embodiments of the present invention have been disclosed as above, but its be not restricted in specification and embodiment it is listed With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, it is of the invention and unlimited In specific details.

Claims (8)

1. a kind of burn and scald spray that the surface of a wound is promoted quickly to heal, which is characterized in that include the material component of following parts by weight:
2. the burn and scald spray that the surface of a wound is promoted quickly to heal as described in claim 1, which is characterized in that the material component It is filling to obtain burn and scald spray formulation after being crushed into powder, then after alcohol dipping, extraction and filtering.
3. the burn and scald spray that the surface of a wound is promoted quickly to heal as claimed in claim 2, which is characterized in that the burn and scald spray Mist preparation contains the ethyl alcohol of 80-85wt%.
4. the burn and scald spray that the surface of a wound is promoted quickly to heal as claimed in claim 2, which is characterized in that the burn and scald spray The first and second aldehyde of polyvinyl alcohol ester of 2-3wt% is further included in mist preparation.
5. the burn and scald spray that the surface of a wound is promoted quickly to heal as claimed in claim 2, which is characterized in that the burn and scald spray The glycerine of 0.7-1.2wt% is further included in mist preparation.
6. promote the burn and scald spray that quickly heals of the surface of a wound as claimed in claim 2, the grain size of the powder for 100~ It is 500 μm, described to be extracted as Dynamic Extraction.
7. the burn and scald spray that the surface of a wound is promoted quickly to heal as claimed in claim 6, using the ethyl alcohol of 90wt% to described Powder carries out Dynamic Extraction.
8. the burn and scald spray that the surface of a wound is promoted quickly to heal as claimed in claim 7, during the Dynamic Extraction, institute The ethyl alcohol for stating 90wt% is 5~8 times of powder volume.
CN201780001789.4A 2017-10-27 2017-10-27 A kind of burn and scald spray that the surface of a wound is promoted quickly to heal Pending CN108064161A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/108111 WO2019080116A1 (en) 2017-10-27 2017-10-27 Burn/scald spray for accelerating wound healing

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Publication Number Publication Date
CN108064161A true CN108064161A (en) 2018-05-22

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559426A (en) * 2019-09-24 2019-12-13 浙江大学医学院附属第四医院 Skin wound healing agent for medical plastic engineering and preparation method thereof
CN113230409A (en) * 2020-12-28 2021-08-10 上海奥茵特生物科技有限公司 Traditional Chinese medicine composite matrix ointment for promoting wound healing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1931265A (en) * 2005-09-16 2007-03-21 贵州环宇药业有限公司 Externally applied Chinese medicine spray for treating burns and scalds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101134053B (en) * 2006-08-29 2011-04-27 黄斌 Pharmaceutical composition capable of treating scald
CN101347532B (en) * 2008-08-26 2011-08-31 周学波 Spray for quick healing of burn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1931265A (en) * 2005-09-16 2007-03-21 贵州环宇药业有限公司 Externally applied Chinese medicine spray for treating burns and scalds

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
南京中医药大学: "《中药大辞典》", 30 June 2014, 上海科学技术出版社 *
曾青兰等: "《生物制药工艺》", 28 February 2015, 华中科技大学出版社 *
李一兵: "中医治疗烧伤的研究进展", 《医学信息(上旬刊)》 *
樊荣丹等: "喷膜剂中成膜材料的研究进展", 《中国药师》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559426A (en) * 2019-09-24 2019-12-13 浙江大学医学院附属第四医院 Skin wound healing agent for medical plastic engineering and preparation method thereof
CN113230409A (en) * 2020-12-28 2021-08-10 上海奥茵特生物科技有限公司 Traditional Chinese medicine composite matrix ointment for promoting wound healing

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