CN109498549A - A kind of ozone oil compound hemorrhoidal cream and preparation method thereof - Google Patents
A kind of ozone oil compound hemorrhoidal cream and preparation method thereof Download PDFInfo
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Abstract
The present invention provides a kind of ozone oil compound hemorrhoidal cream, by weight including following components: 45-60% edible vegetable oil, 9-18% camellia oil, 18-26% linseed oil, 1.5-3% sensitive plant oil, 2-4% niaouli essential oil, 3-5% coptis oil, 0.8-1.2% bay-oil, 0.3-0.5% borneol.A kind of ozone oil compound hemorrhoidal cream provided by the invention, by ozone oil and camellia oil, linseed oil, sensitive plant oil, niaouli essential oil, coptis oil, bay-oil, borneol compound compatibility, there is cooperative compensating effect between each other, therapeutic efficiency is strengthened, effectively raises ozone oil to the curative effect of hemorrhoid.
Description
Technical field
Present invention relates particularly to a kind of formulas for treating hemorrhoid, and in particular to a kind of ozone oil compound hemorrhoidal cream and its preparation
Method.
Background technique
Hemorrhoid are a kind of common diseases positioned at anus area, and any age can all fall ill, but with age, morbidity
Rate gradually increases.The cause of disease about hemorrhoid is there are mainly two types of theory: one, varicose vein theory, it is believed that hemorrhoid are under distal rectal mucous membrane
Venous mass is formed by with veniplex extravasated blood, expansion and the buckling under anal canal skin；Two, the anal cushions down theory of Thomson, recognizes
It is originally the normal anatomical structure in anal canal position, i.e. blood vessel pad for hemorrhoid, is dentate line and the cyclic annular cavernous transformation tissue of the above 1.5cm
Band.
The clinical manifestation of hemorrhoid is hematochezia, pain, itch, falling inflation, and easily initiation fungi, bacterium infection make exacerbation of symptoms.
There are many risk factor of hemorrhoid, and it is main inducing that wherein constipation, long-term alcohol, a large amount of irritable foods of feed and sitting are stood long.Mesh
Preceding to think to the well accepted viewpoint of hemorrhoid treating: therapeutic purposes are releasing symptoms, and non-elimination hemorrhoid body.So surgical operation
Treatment hemorrhoid are not preferred plan, and it is most common treatment method that drug, which applies applying treatment hemorrhoid,.Presently commercially available haemorrhoids ointment item
It is various, some ointment are selected and overweight analgesia, some ointment select overweight anti-inflammatory, some ointment are selected and overweight detumescence, curative effect is unsatisfactory,
It takes effect relatively slow.
Summary of the invention
It is an object of the present invention to solve the deficiency of the existing technology and provide a kind of ozone oil compound hemorrhoidal cream and its preparations
Method.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of ozone oil compound hemorrhoidal cream, by weight including following components: 45-60% edible vegetable oil, the mountain 9-18%
Tea oil, 18-26% linseed oil, 1.5-3% sensitive plant oil, 2-4% niaouli essential oil, 3-5% coptis oil, 0.8-1.2%
Bay-oil, 0.3-0.5% borneol.
Above-mentioned a kind of ozone oil compound hemorrhoidal cream, wherein the edible vegetable oil is selected from olive oil, coconut oil, soybean
One of oil, sunflower oil, corn oil, cottonseed oil, palm oil, rape seed oil, Canola oil, walnut oil, sesame oil, peanut oil
Or it is a variety of.
Above-mentioned a kind of ozone oil compound hemorrhoidal cream, wherein most preferred formula is by weight including following components:
54% edible vegetable oil, 14% camellia oil, 22% linseed oil, 2% sensitive plant oil, 3% niaouli essential oil, 4% coptis oil,
1% bay-oil, 0.4% borneol.
The present invention provides a kind of preparation methods of ozone oil compound hemorrhoidal cream, comprising the following steps:
(1) crystal borneol is weighed according to weight percent be placed in ball mill that be ground into 300 mesh borneol powders spare；
(2) edible vegetable oil, camellia oil, linseed oil are added in ozone oil curing reaction device according to weight percent,
Vegetable oil, camellia oil, linseed oil form miscella in ozone oil curing reaction device；Start ozone curing reaction device, to ozone
It is passed through ozone gas in oily curing reaction device, reaction stops logical when ozonide content reaches set quota value into miscella
Enter ozone gas, generates ozone oil mixture in ozone oil curing reaction device at this time；
(4) sensitive plant oil, niaouli essential oil, coptis oil, bay-oil are added to ozone oil according to weight percent
In curing reaction device, it is mixed evenly with the ozone oil mixture generated in step (3)；
(5) borneol powder is added in ozone curing reaction device, is mixed with the mixture formed in step (4) equal
It is even；
(6) stop ozone curing reaction device, discharging, packing packaging obtain ozone oil compound hemorrhoidal cream.
Ozone is also known as three elemental oxygens, is a kind of native oxidant, ozone be a kind of wide spectrum, efficiently, quickly, safety, nothing
The sterilization gas of secondary pollution can kill the various pathogen such as bacterial spore, virus, fungi.Ozone oil is solidified using ozone
Pure ozone gas is reacted a kind of pure natural mixture generated by technology with food grade vegetable oil.Ozone oil can be applied to skin
Skin, the antibacterial of mucous membrane, anti-inflammatory, it is antipruritic, removing toxic substances etc., ozone oil have broad-spectrum, rapidity, safety, penetrability,
It has no drug resistance；At present medically gradually replaced antibiotic, hormone and be widely used.Folk prescription ozone oil has powerful
Bactericidal antiphlogistic, anti-itch detoxification effect, thus the symptom of all kinds of hemorrhoid can be cured, swelling and pain, inflammation, pruritus ani can be eliminated,
Promote the healing of anal fissure affected part, reduce internal piles, improve vertical pendant sense etc., while the oxygen element that ozone oil decomposition generates can improve microcirculation
Obstacle promotes blood circulation, and can alleviate pain due to hemorrhoid rapidly, eliminates hemorrhoid oedema, to achieve the purpose that cure all kinds of hemorrhoid.
However, since ozone oil has subexcite to skin, coated in there is slight tingling sensation on mucous membrane；Also some people can not like yet
The distinctive raw meat grass smell of ozone oil, these factors affect popularization and use of the ozone oil in treatment hemorrhoid.The present invention can be very
Good solves the above problems.
Camellia oil is squeezed using the seed of Wild Camellia oleifera Abel tree.Camellia oil has activating microcirculation and removing stasis medicinal, clearing away heat and eliminating dampeness, kills
The effect of the effect of worm is detoxified, the red, detumescence of capable of disappearing." tea oil is cooler, cooling blood and hemostasis, heat-clearing solution for record in Compendium of Material Medica
Poison "." detailed outline is picked up any lost article from the road " records " tea oil can treat hemorrhoid, move back damp and hot "." Chinese Pharmacopoeia " (nineteen ninety-five version) using camellia oil as
Medicinal oil records.The cooling blood and hemostasis of camellia oil, blood circulation invigorating efficacies just can be relieved subexcite of the ozone oil to skin, thus
Mitigate ozone oil to the slight tingling sensation of mucous membrane.
When preparing linseed oil, flax oilseeds crude oil first is made through cold-press with linseed, then filter through coarse filtration, essence, is low
The processing steps such as warm crystallization, filter at low temperature paraffin removal obtain linseed oil.Unsaturated fatty acid content is high in linseed oil, has to skin
Excellent affinity and penetration, is easy to be absorbed by the skin, and can be used to supplement lipid components required for skin, maintain and increase
The normal configuration and function of strong Skin Cell film and cytoplasm；High-quality cold pressed flax seed oil is for treatment skin allergy, wet
The inflammations such as rash, acne, chap, infant anthma, skin burn have apparent effect.As a kind of rare containing ω -3 fat
The crude vegetal of acid, there are also some special therapeutic efficiencies, such as linseed oil can play anti-inflammatory, antiallergy and anti-increasing for linseed oil
Raw effect, ω -3 can improve the anti-inflammatory power of leucocyte in human body, reduce the generation of inflammation.These function that linseed oil has
Effect, after ozone oil compound compatibility, can effectively improve ozone oil to the curative effect of hemorrhoid.
Sensitive plant oil is to be obtained using sensitive plant herb using supercritical CO 2 extraction technology, is a kind of pale yellow
Color transparency liquid essential oil, sensitive plant oil deviate from noxious material mimosine.Sensitive plant has calm tranquilizing the mind, hemostasis convergence, the scattered stasis of blood to stop
Bitterly, detoxify, receive sword and other effects, treating swelling and pain by traumatic injury is controlled in external application, sore swollen toxin, hemoptysis, shingles zoster, the effect of having much alleviating pain and detumescence.
The essence of the dense sensitive plant of sensitive plant oil, the effect of holding sensitive plant.The present invention selects sensitive plant oil, first is that utilizing the medicine of sensitive plant oil
With therapeutic efficiency, second is that the fragrance with exotic atmosphere and pleasant that sensitive plant oil is had is used to reconcile ozone oil itself
Raw meat grass smell.
Niaouli essential oil is that the leaf for distilling plant niaouli or sprout obtain, and is a kind of in pistac
Essential oil.The synergistic effect of the ingredients such as sesquiterpenoid contained by niaouli essential oil, sesquiterpene, monoterpene alcohol can be disease-resistant
Malicious, anti-infective, anti-inflammatory antiallergy, can strengthen immunity, there is the mild therapeutic effect of safety.Niaouli essential oil is referred to as
The patron saint of skin and mucous membrane, in niaouli essential oil 4 alcohol of terpinenes and linalool is mild and effective antimicrobial component for
Cleaning and treatment wound, burn, hemorrhoid, malignant boil furuncle, bite by mosquitos have good effect, may additionally facilitate skin cell tissue's growth.
In addition, niaouli essential oil have it is good releive, calm, anti-spasm and itching-relieving action, can reduce hemorrhoid illness.
Coptis oil is after crushing the rhizome of scrophulariaceae Radix picrorrhizae or Tibet picrorhiza rhizome, to obtain through leaching extraction technique
, it is a kind of in flaxen liquid oil.The coptis has effects that heat-clearing, cool blood, eliminating dampness, and controlling infantile malnutrition due to digestive disturbances or intestinalparasites disease, hemorrhoid complicated by anal fistula, sore etc. has
Good effect.The present invention by liquid coptis oil and other vegetable oil mixture, the rate of release of the active drug ingredient of the coptis and
Burst size can greatly improve, and enhance its therapeutic effect.
Bay-oil is the natural plants essence being obtained by extraction in the petal for spending the larger gold osmanthus in golden yellow to spend with solvent method
Oil.Bay-oil can have the unique effects of quickly and effectively releive sufferings and muscular tone with cool blood ease constipation, the hemorrhoid that disappear of stopping blooding.Sweet osmanthus
Oil can make to accelerate skin blood circulation, while the unique perfume of bay-oil can eliminate the raw meat grass smell of ozone oil.
Borneol is to be obtained by composite family Blumea balsamifera cauline leaf or lauraceae plant borneol camphor tree branches and leaves through steam distillation and recrystallizing
Crystal object.Borneol has the effect of clearing heat-fire, swelling and pain relieving, antipruritic anti-corrosion, and the present invention compounds borneol in ozone oil, just
Be borneol to be utilized have swelling and pain relieving, the effect of anti-corrosion is antipruritic, mitigate irritation, feeling of pain of the ozone oil to skin.By
It is solid-like particle in borneol, insoluble in ozone oil, crystal borneol is placed in ball mill by the present invention is ground into 300 mesh borneols
Powder is spare, and powdered borneol is conducive to the dispersibility of drug, and is easier to dissolve in ozone oil, is easier to effective component
Skin absorbs.
In conclusion by adopting the above-described technical solution, compared with prior art, the present invention having the advantage that
A kind of ozone oil compound hemorrhoidal cream provided by the invention is oily, green by ozone oil and camellia oil, linseed oil, sensitive plant
Flower Melaleuca oil, coptis oil, bay-oil, borneol compound compatibility, have cooperative compensating effect between each other, strengthen treatment function
Effect, effectively raises ozone oil to the curative effect of hemorrhoid.
A kind of ozone oil compound hemorrhoidal cream prepared by the present invention has good antibacterial, anti-inflammatory, antipruritic, detumescence, promotes anus
The effect for splitting affected part healing, reducing internal piles, improving vertical pendant sense, while also there is cooling blood and hemostasis, town with the fragrance of pleasant
Quiet, analgesic, activating microcirculation and removing stasis medicinal, the effect for promoting epidermal cell tissue resorption, can accelerate capillary blood to recycle, reach and releive
The effect of release mitigates ozone oil to the slight tingling sensation of mucous membrane, effectively raises ozone oil to the curative effect of hemorrhoid.
Specific embodiment
A specific embodiment of the invention is further described in detail below.
Embodiment 1
It weighs 400g crystal borneol and is placed in ball mill that be ground into 300 mesh borneol powders spare；Weigh 49Kg olive oil,
5Kg coconut oil, 14Kg camellia oil, 22Kg linseed oil are added in ozone oil curing reaction device, start ozone curing reaction device, smelly
Oxygen oil curing reaction device is made ozone gas by electrolysis water and is passed through in ozone oil curing reaction device, reacts smelly into miscella
When oxide content reaches set quota value, stops logical ozone gas, form ozone oil mixture at this time.Weigh 2Kg sensitive plant
Oil, 3Kg niaouli essential oil, 4Kg coptis oil, 1Kg bay-oil are added in ozone oil curing reaction device, the ozone with generation
Oil mixture is mixed evenly, and then borneol powder is added in ozone oil curing reaction device, is stopped after being mixed evenly
Only ozone curing reaction device, discharging, packing packaging, obtains a kind of ozone oil compound hemorrhoidal cream.
Embodiment 2
It weighs 380g crystal borneol and is placed in ball mill that be ground into 300 mesh borneol powders spare；Weigh 48Kg olive oil,
4Kg palm oil, 13Kg camellia oil, 20Kg linseed oil are added in ozone oil curing reaction device, are started ozone curing reaction device, are pressed
Conventional practices are passed through ozone gas into ozone oil curing reaction device, and reaction ozonide content into miscella reaches rule
When determining index value, stops logical ozone gas, form ozone oil mixture in ozone oil curing reaction device at this time.1.8Kg is weighed to contain
Shy grass oil, 2.8Kg niaouli essential oil, 3.6Kg coptis oil, 0.8Kg bay-oil are added in ozone oil curing reaction device, with
The ozone oil mixture of generation is mixed evenly.Borneol powder is added in ozone oil curing reaction device, is mixed equal
Stop ozone curing reaction device after even, discharging, packing packaging obtain a kind of ozone oil compound hemorrhoidal cream.
Embodiment 3
It weighs 430g crystal borneol and is placed in ball mill that be ground into 300 mesh borneol powders spare；Weigh 52Kg olive oil,
6Kg coconut oil, 15Kg camellia oil, 22Kg linseed oil are added in ozone oil curing reaction device, are started ozone curing reaction device, are pressed
Conventional practices are passed through ozone gas into ozone oil curing reaction device, and reaction ozonide content into miscella reaches rule
When determining index value, stops logical ozone gas, form ozone oil mixture in ozone oil curing reaction device at this time.2.2Kg is weighed to contain
Shy grass oil, 3.2Kg niaouli essential oil, 4.2Kg coptis oil, 1.2Kg bay-oil are added in ozone oil curing reaction device, with
The ozone oil mixture of generation is mixed evenly.Borneol powder is added in ozone oil curing reaction device, is mixed equal
Stop ozone curing reaction device after even, discharging, packing packaging obtain a kind of ozone oil compound hemorrhoidal cream.
Embodiment described above is merely to illustrate technical idea and feature of the invention, in the art its object is to make
Technical staff can understand the content of the present invention and implement it accordingly, patent model of the invention only cannot be limited with the present embodiment
It encloses, i.e., it is all according to same changes or modifications made by disclosed spirit, it still falls in the scope of the patents of the invention.
Claims (4)
1. a kind of ozone oil compound hemorrhoidal cream, which is characterized in that by weight including following components: 45-60% edible vegetable oil,
9-18% camellia oil, 18-26% linseed oil, 1.5-3% sensitive plant oil, 2-4% niaouli essential oil, 3-5% coptis oil,
0.8-1.2% bay-oil, 0.3-0.5% borneol.
2. a kind of ozone oil compound hemorrhoidal cream according to claim 1, which is characterized in that the edible vegetable oil is selected from olive
Olive oil, coconut oil, soybean oil, sunflower oil, corn oil, cottonseed oil, palm oil, rape seed oil, Canola oil, walnut oil, sesame
One of oil, peanut oil are a variety of.
3. a kind of ozone oil compound hemorrhoidal cream according to claim 1, which is characterized in that by weight include with the following group
Point: 54% edible vegetable oil, 14% camellia oil, 22% linseed oil, 2% sensitive plant oil, 3% niaouli essential oil, 4% coptis
Oil, 1% bay-oil, 0.4% borneol.
4. a kind of preparation method of ozone oil compound hemorrhoidal cream, which comprises the following steps:
(1) crystal borneol is weighed according to weight percent be placed in ball mill that be ground into 300 mesh borneol powders spare；
(2) edible vegetable oil, camellia oil, linseed oil are added in ozone oil curing reaction device according to weight percent, plant
Oil, camellia oil, linseed oil form miscella in ozone oil curing reaction device；Start ozone curing reaction device, it is solid to ozone oil
Change in reactor and be passed through ozone gas, when ozonide content reaches set quota value into miscella, stopping is passed through smelly for reaction
Carrier of oxygen generates ozone oil mixture in ozone oil curing reaction device at this time；
(4) sensitive plant oil, niaouli essential oil, coptis oil, bay-oil are added to ozone oil solidification according to weight percent
In reactor, it is mixed evenly with the ozone oil mixture generated in step (3)；
(5) borneol powder is added in ozone curing reaction device, is mixed evenly with the mixture formed in step (4)；
(6) stop ozone curing reaction device, discharging, packing packaging obtain ozone oil compound hemorrhoidal cream.
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| CN110179856A (en) * | 2019-07-16 | 2019-08-30 | 深圳市橘井舒泉技术有限公司 | Medical ozone oil and preparation method thereof |
| CN110585440A (en) * | 2019-10-29 | 2019-12-20 | 余浚龙 | Ozone base oil and ozone oil |
| CN110680846A (en) * | 2019-09-30 | 2020-01-14 | 湖北仟枝生物科技有限公司 | Ozone hemorrhoid ointment and preparation method thereof |
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| US20150209470A1 (en) * | 2014-01-28 | 2015-07-30 | John D. Young | Oxygenated Oil Ointment |
| CN107343894A (en) * | 2017-07-07 | 2017-11-14 | 吴潮新 | The medicine and preparation method of the blue or green sub- ozone oil treatment hemorrhoid of bur |
| CN107349293A (en) * | 2017-08-05 | 2017-11-17 | 宁远县兴泰生物科技有限责任公司 | A kind of compound ozone oil and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110179856A (en) * | 2019-07-16 | 2019-08-30 | 深圳市橘井舒泉技术有限公司 | Medical ozone oil and preparation method thereof |
| CN110680846A (en) * | 2019-09-30 | 2020-01-14 | 湖北仟枝生物科技有限公司 | Ozone hemorrhoid ointment and preparation method thereof |
| CN110585440A (en) * | 2019-10-29 | 2019-12-20 | 余浚龙 | Ozone base oil and ozone oil |
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