CN101347532B - Spray for quick healing of burn - Google Patents
Spray for quick healing of burn Download PDFInfo
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- CN101347532B CN101347532B CN2008100458902A CN200810045890A CN101347532B CN 101347532 B CN101347532 B CN 101347532B CN 2008100458902 A CN2008100458902 A CN 2008100458902A CN 200810045890 A CN200810045890 A CN 200810045890A CN 101347532 B CN101347532 B CN 101347532B
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Abstract
The invention belongs to the field of Chinese medicines and relates to a quick healing spray for burn and a preparation technique thereof. The quick healing spray is essentially composed of 80-105 parts of garden burnet, 40-75 parts of euphorbia humifusa, 20-25 parts of common cissampelos herb, 20-25 parts of calcined oyster, 10-15 parts of calcined plaster and 10-15 parts of cutch. The quick healing spray has the efficacies of clearing away heat and toxic materials, dispelling heat from blood to stop bleeding, resisting bacteria, diminishing inflammation, calming, alleviating pains, promoting granulation and astringing wounds. The quick healing spray can be applied to the treatment of large-area and deep burns and scalds caused by various physical and chemical factors through external application, and can be used for treating scorch and injuries on the respiratory tract and the esophagus through oral administration. Furthermore, the quick healing spray can effectively eliminate thermotoxin, prevent body fluid from leaking out, facilitate quick escharosis, avoid infection, eliminate scar and restore sweat glands. Moreover, the quick healing spray of the invention is not restricted by environmental conditions and has significant advantages for clinical treatment, field first aid of the industries like iron and steel, smelting, chemical engineering, thermal electricity, heating industry, fire fighting, field working as well as the field first aid for the burns and wounds caused by various natural disasters and wartime or unexpected group injuries.
Description
Technical field the invention belongs to technical field of Chinese medicines, relates to a kind of Chinese medicine preparation and preparation technology thereof, particularly a kind of external-used burn and scald treating, wound, and orally taken for curing respiratory tract, esophagus are burnt and the medicine of the spray for quick healing of burn that damages is formed and preparation technology.
Background technology development of industry and agriculture and natural disaster make the burn incidence rate more and more higher, mortality rate and disability rate are high.The clinical treatment difficult problem that faces so far of burning has six: the first, endotoxic effective treatment; The second, stop body fluid to ooze out; The 3rd, the infection after the infection of burn wound, particularly large tracts of land, the deep burn; The 4th, scar hyperplasia; The 5th, rebuild sweat gland, it is unimpeded to recover sweat gland; The 6th, effective treatment of inhalation injury.Present clinical burn medicine mostly is tincture, unguentum, oil preparation, antibiotic greatly.Tincture dose medicament is an ethanol extraction, and huge stimulation can increase the probability that causes death because of the pain shock.Unguentum, oil preparation medicine hydrability are relatively poor, effect is slow, have formed the maximum that thermotoxin effluxes jointly with the wound surface occlusive dressing and have hindered.Antibiotic generally use makes antibacterial that the drug resistance transition take place and strain increases, and the situation that bacterial resistance speed is unable to catch up with in antibiotic progress far away occurred.
In JIUYUE, 2006, in the 4th whole nation burn treatment symposium, be the theme with " burn infection treatment new development ", broad research burn is clinical to be faced: shock, infection, nutrition, water power alkali matter and acid-base balance, visceral lesion ... etc. basic problem.The burn medical circle has analgesia in research always, reduce ooze out, be beneficial to drain, protect wound surface, few side effects, wound healing after the ideal burn wound medication of advantage such as few, the low price of cicatrix.
Summary of the invention the purpose of this invention is to provide a kind of external curing by burn and scald due to the various chemical factors, takes orally effectively to treat the Chinese medicine preparation of burning and damaging and the preparation technology thereof of respiratory tract, esophagus.
The present invention is achieved through the following technical solutions:
Medicine provided by the present invention is made by following medicaments in part by weight: 80 parts～105 parts of Radix Sanguisorbaes; 40 parts～75 parts of Herba Euphorbiae Humifusaes; 20 parts～25 parts of Herba Cissampelotis pareiae; 20 parts～25 parts of Concha Ostreae (calcined)s; 10 parts～15 parts of Gypsum Fibrosum Preparatum; 10 parts～15 parts in catechu.
In the above-mentioned raw materials, Radix Sanguisorbae is a monarch drug, has cooling blood for hemostasis, sedation-analgesia, anti-inflammation and sterilization, removes and dislike meat, end pus and blood, convergence, treatment incised wound, control function such as burn; Herba Euphorbiae Humifusae has heat-clearing and toxic substances removing, cooling blood for hemostasis, and functions such as antibiotic and sterilizing, Herba Cissampelotis pareiae has relexation to striped muscle, has the function of pain relieving, hemostasis, granulation promoting; Gypsum Fibrosum Preparatum has promoting tissue regeneration and ulcer healing, the pain that relieves the pain, and controlling bursts does not close up, the function of the burning hot wound of soup; , be equipped with that Gypsum Fibrosum Preparatum, Concha Ostreae (calcined) can be played removing dampness altogether, hold back skin ulcer, the effect of granulation promoting, be equipped with Herba Euphorbiae Humifusae, catechu to strengthen its detoxifcation, sterilization, removing heat from blood, hemostatic effect.
External preparation dosage form of the present invention is a spray, in to take preparation formulation be water preparation, the respiratory tract preparation formulation is an aerosol.
Preparation technology of the present invention is characterized in that, it prepares by following step:
1. by the above-mentioned prescription thing weight fraction raw material of getting it filled;
2. Radix Sanguisorbae, Concha Ostreae (calcined), Gypsum Fibrosum Preparatum are soaked respectively roll, pulverization process;
3. under condition of normal pressure, decoct after adding water by the medicine of above-mentioned proportioning weight fraction;
4. be adjusted to slow fire boiling after intense fire boils, the temperature constant interval is 95 ℃～120 ℃;
5. remove slag, filter, concentrate, promptly get medicinal liquid;
6. sealing and standing, sucking filtration promptly get the spray medicinal liquid.
Preferred, prepare by following step:
1) steeps Radix Sanguisorbae 1～3 hour with the water logging of 6 times of Radix Sanguisorbae weight fraction, be rolled into lamellar behind the drainage; Concha Ostreae (calcined), Gypsum Fibrosum Preparatum are pulverized;
2) water that the medicine Radix Sanguisorbae of proportioning weight fraction, Concha Ostreae (calcined), Gypsum Fibrosum Preparatum is added 16 times of Radix Sanguisorbaes, Concha Ostreae (calcined) and Gypsum Fibrosum Preparatum weight fraction decocts under normal pressure;
3) be adjusted to slow fire boiling after intense fire boils, the temperature constant interval is 95 ℃～120 ℃, after boiling 1 hour, put into the medicine catechu of proportioning weight fraction, adding 10 is the water of tea weight fraction extremely, intense fire boils back slow fire and boiled 1 hour, adds medicine Herba Euphorbiae Humifusae, the Herba Cissampelotis pareiae of proportioning weight fraction again, and the water that adds 10 times of Herba Euphorbiae Humifusaes and Herba Cissampelotis pareiae weight fraction decocts under normal pressure;
4) decoction was removed slag, is filtered after 40 minutes, reconcentration 2 hours, and concentrated medicament weight is 7: 1 with the ratio that the proportioning drug weight is divided;
5) left standstill 1～2 month at 18 ℃～25 ℃ environment lower seals, sucking filtration promptly gets oral, spray, aerosol medicinal liquid.
The present invention has heat-clearing and toxic substances removing, cooling blood for hemostasis, anti-inflammation, the effect of sedation-analgesia, promoting tissue regeneration and ulcer healing.External is applicable to treatment by large tracts of land, deep burn due to the various chemical factors, and for oral administration being applicable to treated burning and damaging of respiratory tract, esophagus.Can effectively treat thermotoxin, stop body fluid to ooze out, incrustation fast stops to infect, and eliminates cicatrix, rebuilds sweat gland.
Characteristics of the present invention are: adopt exposure method, in 30 minutes pain relief is disappeared then; Effectively stop body fluid to ooze out in 3 hours.The wound surface of Gan Raning self did not form restorative incrustation in 36 hours; The wound surface that has infected is eliminated in 48 hours and is infected, and forms restorative incrustation, and no pus under the crust; The degree of depth, large tracts of land burn and scald, healing decrustation in 10-20 days after the medication; Slightly, the small size burn and scald, after the medication 7 days the healing decrustation; The no cicatrix in healing back, the non-pigment calmness; The wound surface sweat gland is unimpeded, makes skin recover normal physiological function.Medicine belongs to pure Chinese medicinal preparation, and is alcohol-free, non-stimulated, without any side effects; Be not subjected to the restriction of medical condition, easy to use, to clinical treatment, to the field first aid of industry one lines such as iron and steel, smelting, chemical industry, thermoelectricity, thermal technology's industry, fire-fighting, field, the field first aid that wartime, the sudden group of colony is injured burn, wound due to the various natural disasters has significant superiority.Owing to adopt the Chinese medicine component, herb resource is abundant, and is cheap.
Each medicine preferred dosage point is as follows in the above-mentioned prescription of the specific embodiment:
Example 1. is with the material medicine of following weight fraction: 80 parts of Radix Sanguisorbaes, 75 parts of Herba Euphorbiae Humifusaes, 15 parts of Gypsum Fibrosum Preparatum.
Example 2. is with the material medicine of following weight fraction: 95 parts of Radix Sanguisorbaes, 20 parts of Herba Cissampelotis pareiae, 25 parts of Concha Ostreae (calcined)s, 10 parts of Gypsum Fibrosum Preparatum.Example 3. is with the material medicine of following weight fraction: 105 parts of Radix Sanguisorbaes, 45 parts of Herba Euphorbiae Humifusaes, 20 parts of Concha Ostreae (calcined)s, 15 parts of Gypsum Fibrosum Preparatum, 15 parts in catechu.
Its using method of this medicine and dosage are:
One, external
1. medicine uses and takes exposure method.
2. clinical treatment can clean with cold water or mineral water with normal saline or distilled water, in-situ curing and pollute wound surface, and the person cuts off part bubble skin the blister, makes dependent drainage, blots the wound surface cleanout fluid.
3. large tracts of land, dark II °, III ° burn and scald patient direct drug injection liquid were soaked wound surface 15 minutes, directly sprayed wound surface once with medicinal liquid in later per 40 minutes.
4. shallow II ° of middle small size, dark II ° of burn and scald the wounded were sprayed medicine once in per 40 minutes after the debridement, and night can not medication.
5. use other medicines to use the patient that hinders of this medicament again instead, the left drug of wound surface must have been cleaned up, sprayed wound surface with medicinal liquid after blotting cleanout fluid.
6. before medication next day, with medication again behind the above-mentioned same method cleaning wound surface, administration time is identical.
7. during the wound surface incrustation, be sure not the people, it is come off naturally for peeling off crust.After crust comes off fully, continue medication 3～5 days, every day 3 times.
Two, for oral administration
1. esophagus decreases the wounded and gargles dirt in the removing oral cavity with normal saline, distilled water, cold water, mineral water.
2. medicinal liquid is sucked 1 minute, and slowly the infiltration pharynx is obeyed again.
3. first day 15ml/2h obeys 6 times altogether; Second day 15ml/2h obeys 5 times altogether; Began and later 15ml/3h every day 3 times on the 3rd day; Until recovery from illness.
The treatment example:
1.1999.4.29, chapter * *, the man, 9 years old, live in sea market Xi Kanglu, left thigh, the right crus of diaphragm back of the body are scalded, injured area 5%, shallow II °, dark II ° of mixed type, decrustation on May 5, wound healing rate 100%;
2.1999.4.29, Korea Spro * *, the man, 1 years old half, live in sea market Qingpu town, the both hands upper limb is scalded, injured area 8%, shallow II °, dark II ° of mixed type, decrustation on May 6, wound healing rate 100%;
3.2001.5.31, Feng * *, the man 32 years old, lives Wuhan City's Jiangxia District, the facial scald, injured area 14%, shallow II °, dark II ° of mixed type, decrustation on June 10, wound healing rate 100%;
4.2001.6.6, Liao * *, the man 64 years old, lives in Wuchang Fu An for sleeping in, the facial scald, injured area 9%, shallow II °, dark II ° of mixed type, decrustation on June 17, wound healing rate 100%;
5.2001.6.14, old * *, the man, 37 years old, live Wuchang liberation bridge, right upper extremity is scalded, injured area 4%, shallow II °, dark II ° of mixed type, decrustation on June 28, wound healing rate 100%;
6.2001.6.21, recklessly * *, the man 48 years old, lives Wuchang Shen Jia one village, facial burn, injured area 3%, dark II °, decrustation on June 21, wound healing rate 100%;
7.2001.6.28, open * *, the man 48 years old, lives the Wuhan Huangpo District, the facial scald, injured area 8%, shallow II °, dark II ° of mixed type, decrustation on July 7, wound healing rate 100%;
8.2001.7.21, recklessly * *, the woman 42 years old, lives fruit lake, Wuchang, both hands burn of upper limb, injured area 7%, shallow II °, dark II ° of mixed type, decrustation on August 11, wound healing rate 100%;
9.2001.7.23, the palace * *, the woman 36 years old, lives Wuchang District, both hands burn of upper limb, injured area 5%, shallow II °, dark II ° of mixed type, decrustation on August 3, wound healing rate 100%;
10.2001.8.2, Liu *, the man 30 years old, lives Zhong Shan main road, Wuhan City, left leg burn, injured area 3%, shallow II °, dark II ° of mixed type, decrustation on August 16, wound healing rate 100%;
11.2001.8.5, Lee *, the man 19 years old, lives Hubei Huang Po 5 mounds, rear quarters burn, injured area 8%, shallow II °, dark II ° of mixed type, decrustation on August 20, wound healing rate 100%;
12.2001.8.6, Ke * *, the man 49 years old, lives in Wuhan Han Zhengjie, head, burn of neck region, injured area 45%, shallow II °, dark II ° of mixed type, decrustation on August 23, wound healing rate 100%;
13.2001.8.9, the week *, the woman 25 years old, lives in Wuhan Han Zhengjie, right lower extremity burn, injured area 3%, shallow II °, dark II ° of mixed type, decrustation on August 29, wound healing rate 100%;
14.2001.8.11, pile * *, the man 27 years old, lives Wuhan City Wuhan Branch, head, face burn, injured area 10%, shallow II °, dark II ° of mixed type, decrustation on August 25, wound healing rate 100%;
15.2001.8.11, what *, the woman, 20 years old, live Wuhan City's Qingshan District, right leg is scalded, injured area 4%, dark II °, decrustation on August 28, wound healing rate 100%;
16.2001.8.16, the king *, the woman, 38 years old, live sub-district, South Lake, Wuhan City, left leg is scalded, injured area 2%, dark II °, decrustation on August 30, wound healing rate 100%;
17.2001.8.22, Lee * *, the woman 38 years old, lives Hankow, Wuhan City two or seven, two lower limb, forerunner's burn, injured area 6%, shallow II °, dark II ° of mixed type, JIUYUE decrustation on the 8th, wound healing rate 100%;
18.2001.8.25, open *, the woman 45 years old, lives liberation main road, Hankow, left upper extremity burn, injured area 3%, dark II °, JIUYUE decrustation on the 11st, wound healing rate 100%;
19.2001.9.10, Liu * *, the man 40 years old, lives Cai of Wuhan City dekan, facial, right forearm burn, injured area 6%, shallow II °, dark II ° of mixed type, JIUYUE decrustation on the 20th, wound healing rate 100%;
20.2001.9.11, poplar * *, the man 32 years old, lives Wuhan City's cultural palace, two burn of lower limb, injured area 4%, dark II °, JIUYUE decrustation on the 25th, wound healing rate 100%.
Claims (3)
1. the spray for quick healing of burn of an external-used burn and scald treating, wound, it is characterized in that: said preparation is to be made by the medicine of following proportion relation: 80 parts～105 parts of Radix Sanguisorbaes, 40 parts～75 parts of Herba Euphorbiae Humifusaes, 20 parts～25 parts of Herba Cissampelotis pareiae, 20 parts～25 parts of Concha Ostreae (calcined)s, 10 parts～15 parts of Gypsum Fibrosum Preparatum, 10 parts～15 parts in catechu.
2. the preparation method of spray for quick healing of burn is characterized in that, it prepares by following step:
1) by the above-mentioned prescription thing weight fraction raw material of getting it filled;
2) Radix Sanguisorbae, Concha Ostreae (calcined), Gypsum Fibrosum Preparatum are soaked respectively roll, pulverization process;
3) under condition of normal pressure, decoct after adding water by the medicine of above-mentioned proportioning weight fraction;
4) be adjusted to slow fire boiling after intense fire boils, the temperature constant interval is 95 ℃～120 ℃;
5) remove slag, filter, concentrate, promptly get medicinal liquid;
6) sealing and standing, sucking filtration promptly get the spray medicinal liquid.
3. spray for quick healing of burn according to claim 2, it is characterized in that: with the cold water soak Radix Sanguisorbae of 6 times of Radix Sanguisorbae weight fraction 1～3 hour, be rolled into lamellar behind the drainage, with Concha Ostreae (calcined), Gypsum Fibrosum Preparatum is pulverized, add 16 times of Radix Sanguisorbaes, Concha Ostreae (calcined), the water of Gypsum Fibrosum Preparatum weight fraction decocts, after boiling 1 hour, add again catechu and 10 extremely the water of tea weight fraction decoct, after boiling 1 hour, add Herba Euphorbiae Humifusae again, Herba Cissampelotis pareiae and 10 times of Herba Euphorbiae Humifusaes, the water of Herba Cissampelotis pareiae weight portion decocts, boil after 40 minutes and remove slag, filter, reconcentration 2 hours, concentrated medicament weight is 7: 1 with the ratio of proportioning medical material weight fraction, leaves standstill 1～2 month at 18 ℃～25 ℃ environment lower seals, sucking filtration promptly makes the spray medicinal liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100458902A CN101347532B (en) | 2008-08-26 | 2008-08-26 | Spray for quick healing of burn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100458902A CN101347532B (en) | 2008-08-26 | 2008-08-26 | Spray for quick healing of burn |
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| Publication Number | Publication Date |
|---|---|
| CN101347532A CN101347532A (en) | 2009-01-21 |
| CN101347532B true CN101347532B (en) | 2011-08-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008100458902A Expired - Fee Related CN101347532B (en) | 2008-08-26 | 2008-08-26 | Spray for quick healing of burn |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735945B (en) * | 2013-09-23 | 2016-05-25 | 新疆吐鲁番地区维吾尔医医院 | A kind of externally applied drug for the treatment of empyrosis |
| CN104984071A (en) * | 2015-07-16 | 2015-10-21 | 周通 | Burn and scald restoration medicine |
| CN108064161A (en) * | 2017-10-27 | 2018-05-22 | 江苏奇力康皮肤药业有限公司 | A kind of burn and scald spray that the surface of a wound is promoted quickly to heal |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380069A (en) * | 2001-04-12 | 2002-11-20 | 潘天保 | Medicine for curing burn and scald and its preparation method |
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2008
- 2008-08-26 CN CN2008100458902A patent/CN101347532B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380069A (en) * | 2001-04-12 | 2002-11-20 | 潘天保 | Medicine for curing burn and scald and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 余以平.草七厘散的临床应用.《福建中医药》.1995,第26卷(第4期),56. * |
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| CN101347532A (en) | 2009-01-21 |
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