CN103463246A - Externally-applied Chinese herbal medicine fast effective preparation capable of treating burns and scalds, and preparation process - Google Patents
Externally-applied Chinese herbal medicine fast effective preparation capable of treating burns and scalds, and preparation process Download PDFInfo
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Abstract
The invention relates to the field of pharmaceutical preparations, and specifically relates to an externally-applied Chinese herbal medicine fast effective preparation capable of treating burns and scalds, and a preparation process. A formula for the externally-applied Chinese herbal medicine fast effective preparation comprises 2-4% of rhubarb extract, 2-4% of coptis chinensis extract, 1-3% of scutellaria baicalensis extract, 1-3% of wild chrysanthemum extract, 1-3% of honeysuckle extract, 1-3% of radix sanguisorbae extract, 1-3% of water-soluble pearl powder and 0.5-1% borneol. Compared with conventional preparations capable of treating the burns and scalds, the externally-applied Chinese herbal medicine fast effective preparation provided by the invention can realize effective functions for curing the burns and scalds by reasonably compounding the above medicines. A maifanite soaking solution is prepared to be used as a solvent; the rhubarb extract, the coptis chinensis extract and the scutellaria baicalensis extract which have the effects of resisting ulcers, resisting bacteria, resisting virus, relieving imflammation and clearing heat, cooling blood and dissipating blood stasis are added; the radix sanguisorbae extract which has the effects of treating burns, preventing and controlling infections and promoting wounds to be healed rapidly is added; the wild chrysanthemum extract and the honeysuckle extract which can disperse wind and clear heat and remove toxicity for detumescence are added; and pearl and borneol which has the functions of preventing corrosion and promoting tissue regeneration, clearing heat to relieve pains are added.
Description
[technical field]
Patent of the present invention relates to field of medicine preparations, specifically a kind of burn and scald Chinese herbal medicine for external use quick-effective preparation and preparation method for the treatment of.
[background technology]
Burn and scald is a kind of common sudden wound, and the skin pathological changes that the burn and scald position occurs is rapid, the superelevation metabolism, can make very soon the subcutaneous tissue immunologic function lose, redness, blister and searing pain appear in moment, carry out effective treatment nursing as failed, just the state of an illness worsens rapidly.
Domestic existing medicine and the technology treatment to burn and scald at present, all exist slow curative effect, easy infection, the difficult healing of wound, and the medicine of some oil, cream class, also can increase the weight of the state of an illness.As a lot of pharmacies, all at a boiling hot skin ulcer oil of selling, the untoward reaction of pointing out according to description has: accidental slight erythema, pruritus, zest pain.And points out to use after need breaking as blister occurred again.Break blister, can form the easy broken skin infection of wound by flow liquid.Slight wound can lead to serious symptom.Be unfavorable for the rapid healing of wound.Deep burn also must just can be cured by surgery skin grafting, the cicatrix retained in various degree after healing, the sequela of even disfeaturing.Allow especially the patient suffering can't bear.Existing medicine and technology obviously can not adapt to the pathologic of scalding the patient and change demand.
[summary of the invention]
For above-mentioned burn and scald pathological change feature rapidly, overcome the weak point that existing medicine and technology exist the treatment of burn and scald, select targetedly medical material to be mixed with permeability strong, onset is the Chinese herbal medicine for external use quick-effective preparation rapidly.Patent of the present invention is the water white transparency water preparation, and energy rapid permeability subcutaneous tissue, have no adverse reaction, non-stimulated, during treatment, refrigerant comfortable, need not prick a blister with a needle.Carry out continuously spray liquid treatment about hour, blister, redness, pain all can disappear voluntarily fast, do not stay any cicatrix pigment.Especially for the nursing of large tracts of land burn, highlight especially its advantage.Composition of medicine can effectively suppress the growth of antibacterial.Realize that antiinflammatory is antibacterial, the therapeutic purposes of putrefaction-removing granulation-promoting.Can ensure preferably normal recovery and the regeneration of cell, the burn wound of finally healing.Make the wound various functions that efficient recovery be arranged.More after, part is smooth, 1 degree, 2 degree, the 3 rear all preventing from scar of degree burn woundes.
Above-mentioned purpose of the present invention, to be achieved by the following technical programs, a kind of formula for the treatment of burn and scald Chinese herbal medicine for external use quick-effective preparation, its component is as follows: make solvent with Maifanitum soak 70~90%, containing Radix Et Rhizoma Rhei extract 2~4%, Rhizoma Coptidis extract 2~4%, Radix Scutellariae extracting solution 1~3%, Flos Chrysanthemi Indici extracting solution 1~3%, Flos Lonicerae extractive solution 1~3%, Radix Sanguisorbae extracting solution 1~3%, Borneolum Syntheticum 0.5~1%.
For increasing curative effect, preferred plan is: described Maifanitum soak 84%.
For increasing curative effect, preferred plan is: described pharmaceutical formulation component is as follows: Radix Et Rhizoma Rhei extract 3%, Rhizoma Coptidis extract 3%, Radix Scutellariae extracting solution 2%, Flos Chrysanthemi Indici extracting solution 2%, Flos Lonicerae extractive solution 2%, Radix Sanguisorbae extracting solution 2%, Borneolum Syntheticum 0.8%.
For increasing curative effect, preferred plan is: described formula constituent is water soluble Margarita powder 1.2% also.
A kind of burn and scald Chinese herbal medicine for external use quick-effective preparation for the treatment of, its optimization formula is: Radix Et Rhizoma Rhei extract 3%, Rhizoma Coptidis extract 3%, Radix Scutellariae extracting solution 2%, Flos Chrysanthemi Indici extracting solution 2%, Flos Lonicerae extractive solution 2%, Radix Sanguisorbae extracting solution 2%, water soluble Margarita powder 1.2%, Borneolum Syntheticum 0.8%, Maifanitum soak 84%.
Described Maifanitum soak is as the solution of brewed Chinese herbal medicine.First, by Maifanitum and Purified Water, by the proportion of 1: 9, soak 2 hours, make the Maifanitum soak after filtration.
The Maifanitum soak is heated to 90~100 ℃.Add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, Borneolum Syntheticum by the component sequencing again; The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain this preparation after ultraviolet radiation for sterilizing and disinfecting.
Preferred version, component adds solvent, adds respectively Radix Et Rhizoma Rhei extraction, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, water soluble Margarita powder, Borneolum Syntheticum with sequencing in proportion.The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain product after ultraviolet radiation for sterilizing and disinfecting.
The effect of selected drug extract is as follows respectively:
Modern medicine proves, Radix Et Rhizoma Rhei has the effects such as antiulcer, antibiotic, antiviral.Effective ingredient: chrysophanic acid, emodin, aloe-emodin.Inducement interferon.For burn due to hot liquid or fire have rush down scorching analgesic, the cooling blood and removing stasis effect.The contained tannin of Radix Et Rhizoma Rhei has good antioxidation and immunoloregulation function; The antibacterial antiulcer heat clearing and damp drying of Rhizoma Coptidis anti-inflammatory and antalgic, eliminating fire and detoxication, reducing the asthenic fever, treat various burns, and burn infection is red and swollen etc.; The clinical practice of Radix Scutellariae is antibiotic not worse than Rhizoma Coptidis, and does not develop immunity to drugs; Radix Sanguisorbae contains a large amount of tannins, and stronger convergence and pressor effect are arranged, and can reduce the permeability of blood vessel, reduces inflammatory exudation, also has obvious bactericidal action simultaneously.The treatment burn can play prevention and infection control, and eliminate pain promotes the effects such as wound surface heals rapidly; According to the Compendium of Material Medica record, " Flos Lonicerae, be good at removing toxic substances to the Flos Lonicerae effect, and since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the merit of dissipation furuncle; The property of Flos Chrysanthemi Indici bitter cold, have the merit of heat-clearing and toxic substances removing, wind and heat dispersing, removing toxic substances and promoting subsidence of swelling; Margarita, Borneolum Syntheticum have respectively the merit of erosion prevention and muscle growing, eliminating fire and detoxication, clearing away heat to alleviate pain, detumescence.By above-mentioned medicinal liquid reasonable compatibility, dissolve in the Maifanitum soak.
Described Maifanitum soak is Maifanitum to be soaked in to water can hold the necessary nearly 20 kinds of elements of human body and the mineral such as potassium, sodium, calcium, magnesium, silicon, violent, titanium, phosphorus.Can strengthen the immunologic function of human body, improve the health anti-infection ability.Make the Skin Cell increased activity.Solution with the Maifanitum soak as this Chinese herbal medicine formula, strengthened the curative effect of medicine.
[concrete enforcement]
A kind of burn and scald Chinese herbal medicine for external use quick-effective preparation for the treatment of, comprise formula as follows: Radix Et Rhizoma Rhei, Rhizoma Coptidis, Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Radix Sanguisorbae, Borneolum Syntheticum, Maifanitum soak.
Embodiment mono-:
Get Radix Et Rhizoma Rhei extract 300 grams, Rhizoma Coptidis extract 250 grams, Radix Scutellariae extracting solution 250 grams, Flos Chrysanthemi Indici extracting solution 200 grams, Flos Lonicerae extractive solution 200 grams, Radix Sanguisorbae extracting solution 200 grams, water soluble Margarita powder 120 grams, Borneolum Syntheticum 80 grams standby.
Get 1000 gram Maifanitums and Purified Water 9000 and soak 2 hours by the proportion of 1: 9, make the Maifanitum soak after filtration, get 8400 gram Maifanitum soaks and heat to 90~100 ℃.Add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, water soluble Margarita powder, Borneolum Syntheticum with sequencing in proportion again.The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain product after ultraviolet radiation for sterilizing and disinfecting.
Embodiment bis-:
Get Radix Et Rhizoma Rhei extract 250 grams, Rhizoma Coptidis extract 250 grams, Radix Scutellariae extracting solution 250 grams, Flos Chrysanthemi Indici extracting solution 250 grams, Flos Lonicerae extractive solution 200 grams, Radix Sanguisorbae extracting solution 200 grams, water soluble Margarita powder 120 gram Borneolum Syntheticum 80 grams standby.
Get 1000 gram Maifanitums and Purified Water 9000 and soak 2 hours by the proportion of 1: 9, make the Maifanitum soak after filtration, get 8400 gram Maifanitum soaks and heat to 90~100 ℃.Add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, water soluble Margarita powder, Borneolum Syntheticum with sequencing in proportion again.The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain product after ultraviolet radiation for sterilizing and disinfecting.
Embodiment tri-:
Get Radix Et Rhizoma Rhei extract 300 grams, Rhizoma Coptidis extract 300 grams, Radix Scutellariae extracting solution 200 grams, Flos Chrysanthemi Indici extracting solution 200 grams, Flos Lonicerae extractive solution 200 grams, Radix Sanguisorbae extracting solution 200 grams, water soluble Margarita powder 120 grams, Borneolum Syntheticum 80 grams standby.,
Get 1000 gram Maifanitums and Purified Water 9000 and soak 2 hours by the proportion of 1: 9, make the Maifanitum soak after filtration, get 8400 gram Maifanitum soaks and heat to 90~100 ℃.Add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, water soluble Margarita powder, Borneolum Syntheticum with sequencing in proportion again.The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain product after ultraviolet radiation for sterilizing and disinfecting.
Application test case one:
Mrs Zhu, 40 years old, live in extra large Xuhui District, on February 7th, 2008, just as the lunar New Year's Day, afternoon is while infusing tea to the guest, accidentally hand thumb is scalded when few just redness, foaming, pain by boiled water, within 16: 34 o'clock, with this product, for its scald position, nurses about half an hour, to 17: 05 o'clock, redness, blister, pain disappear entirely, do not stay any pigment cicatrix.Up to the present, Mrs's Zhu thumb function did not occur abnormal.
Application test case two:
Patient week so-and-so, the man, life in 56 years, people from Guangzhou, Guangdong, when within 2011, February 12 was come here, the right hand is red and swollen severe, armrest wrist place has and is about 7 centimeters, wide 1.5 centimeters, dark 0.5 centimeter badly mutilated rotten wound.Scalded at that time existing two weeks, treated in certain hospital of this city.Every day, medicine injection was hung saline.Always do not get better, the condition of the injury is more and more serious.Bought boiling hot skin ulcer oil and treated in pharmacy, not only do not had improvement, pain is aggravated on the contrary.After using this preparation nursing, mouth takes a turn for the better gradually, and 0.5 centimeter dark wound is Horizon progressively, and after nursing nearly two hours with preparation continuously, the dry Net of wound surface is without rotting, and pain and burning sensation all disappear, and the arm of trying gently to swing one's arm does not think pain yet.Adhere to every day nursing two hours, after nursing in three days, it is normal that the function of arm is also recovered substantially.In succession nursed about ten days, the condition of the injury takes a turn for the better day by day.Finally almost vestige all be can't see.
Application test case three:
Mrs Xing, 36 years old, July 29 in 2011, because of the right hand and arm, by boiled water, scalded the existing a few days, to having bought scald medicament in pharmacy, advance to smear.Not only do not have effect but also redness more and more severe.Come here, only see that she has ulcer of two places, there is the decortication phenomenon many places, and using the preparation in the present invention be its nursing, after nursing first more than one hour, after red and swollen and ulcer symptom has improvement nursing in various degree four times, just substantially well.The wound of ulcer also heals, and congestion and swelling pain disappears substantially.The function of her hand and skin had all recovered normal afterwards.
Application test case four:
Mrs Zhou, live Changning district, Shanghai, the winter of 2011 once, together with friend during Mutton in hot pot, careless right pinkie is encountered chaffy dish, immediately, is scalded position to bleach, look also whiter than the Carnis caprae seu ovis of having cooked by scalding, also some is outstanding for white position, and this is because of due to carbonization.The inventor is just scalded the position dropping liquid with the burn and scald quick-effective preparation of carrying at her, and improving appears in carbonization phenomenon soon, at first, looks less white, and has calmed down a bit at outstanding position.Continue dropping liquid in affected part, skin restores gradually, afterwards recovery from illness very soon.Facts have proved and presented carbonization by boiling hot position, degree of reaching III burn and scald, with medicament is done the treatment nursing in time, just can turn danger into safety fast.
Confirmed the actual effect of patent of the present invention from above-mentioned case of having cured,
To I degree burn and scald, use immediately nursing several minutes, just can eliminate and scald impact, can scar, pigment.
The II degree is scalded, and redness goes out blister, and causes pain: use immediately this product to be treated, just can eliminate the burn and scald impact about 1 hour, in use, need not break blister, need not wrap up and change dressings, redness, blister, pain can disappear, and do not produce cicatrix, pigment;
The III degree is scalded or festered: use this product treatment nursing, coordinate the oral anti-inflammatory drug thing, in case infect, through about one week, wound healing, but preventing from scar pigment, also without any sequela; And medical institutions are about half a year treatment time, large tracts of land III degree burn trauma face finally also will lean on skin-grafting can cover healing.The functional disorder of more, often causing contracture deformity, disability, the sequela of even disfeaturing.
If, as family and the anti-standing medicine of labor, just precautions averts perils, this preparation not only has specially good effect for the nursing of burn and scald, and, also very good for the therapeutic effect by ultraviolet burn.
Patented product of the present invention is again the good product of energy-conserving and environment-protective, and production process is without chemical blowdown, and use procedure can not produce oils and fats and dust yet, can not stain clothing and contaminated environment, is the good product of environmental protection.Medicinal liquid is thickness not, and concentration is not high, and the medicinal raw material cost is starkly lower than cream frost and powder, also greatly saves the regulation expense of slurry and the environmental pollution of clothing.
The herbal raw material extracting solution of patented product formula of the present invention is easily purchased, and does not belong to well sold and in short supply medical material, also without violated composition.
Claims (10)
1. a treatment burn and scald Chinese herbal medicine for external use quick-effective preparation, is characterized in that, it is as follows that described preparation comprises formula: Radix Et Rhizoma Rhei, Rhizoma Coptidis, Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Radix Sanguisorbae, Borneolum Syntheticum, Maifanitum soak.
2. according to the described a kind of burn and scald Chinese herbal medicine for external use quick-effective preparation for the treatment of of claims 1, it is characterized in that, described preparation is made solvent with Maifanitum soak 70~90%, the following Radix Et Rhizoma Rhei extract 2~4% of its formula constituent, Rhizoma Coptidis extract 2~4%, Radix Scutellariae extracting solution 1~3%, Flos Chrysanthemi Indici extracting solution 1~3%, Flos Lonicerae extractive solution 1~3%, Radix Sanguisorbae extracting solution 1~3%, Borneolum Syntheticum 0.5~1%.
3. according to claims 1 and 2 described a kind of burn and scald Chinese herbal medicine for external use quick-effective preparations for the treatment of, it is characterized in that described Maifanitum soak 84%.
4. according to claims 1 and 2 described a kind of burn and scald Chinese herbal medicine for external use quick-effective preparations for the treatment of, it is characterized in that, described pharmaceutical formulation component is as follows: Radix Et Rhizoma Rhei extract 3%, Rhizoma Coptidis extract 3%, Radix Scutellariae extracting solution 2%, Flos Chrysanthemi Indici extracting solution 2%, Flos Lonicerae extractive solution 2%, Radix Sanguisorbae extracting solution 2%, Borneolum Syntheticum 0.8%.
5. according to claims 1 and 2 described a kind of burn and scald Chinese herbal medicine for external use quick-effective preparations for the treatment of, it is characterized in that, described formula constituent also comprises water soluble Margarita powder 1~3%.
6. according to claims 1 and 2 described a kind of burn and scald Chinese herbal medicine for external use quick-effective preparations for the treatment of, it is characterized in that described formula constituent water soluble Margarita powder 1.2%.
7. according to the described a kind of preparation method for the treatment of burn and scald Chinese herbal medicine for external use quick-effective preparation of claim 1 to 6, it is characterized in that, the preparation method of described solvent Maifanitum soak is: first by Maifanitum and Purified Water, by the proportion of 1: 9, soak 2 hours, make the Maifanitum soak after filtration.
8. a kind of preparation method for the treatment of burn and scald Chinese herbal medicine for external use quick-effective preparation according to claim 7, it is characterized in that, the preparation method of described preparation is: the Maifanitum soak is heated to 90~100 ℃, then add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, Borneolum Syntheticum; The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain this preparation after ultraviolet radiation for sterilizing and disinfecting.
9. a kind of preparation method for the treatment of burn and scald Chinese herbal medicine for external use quick-effective preparation according to claim 7, it is characterized in that, the preparation method of described preparation is: the Maifanitum soak is heated to 90~100 ℃, then add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, Borneolum Syntheticum by the component sequencing; The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain this preparation after ultraviolet radiation for sterilizing and disinfecting.
10. a kind of preparation method for the treatment of burn and scald Chinese herbal medicine for external use quick-effective preparation according to claim 7, it is characterized in that, the preparation method of described preparation is: the Maifanitum soak is heated to 90~100 ℃, then add Radix Et Rhizoma Rhei extract, Rhizoma Coptidis extract, Radix Scutellariae extracting solution, Flos Chrysanthemi Indici extracting solution, Flos Lonicerae extractive solution, Radix Sanguisorbae extracting solution, water soluble Margarita powder, Borneolum Syntheticum by the component sequencing; The dissolving that stirs while feeding in raw material, make combined drug liquid after filtration, is filled in container bottle after cooling, and sealing, more obtain this preparation after ultraviolet radiation for sterilizing and disinfecting.
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Cited By (3)
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CN106512069A (en) * | 2016-09-28 | 2017-03-22 | 四川三和医用材料有限公司 | Medical pressure-sensitive adhesive anti-inflammatory and bactericidal additive |
CN106512068A (en) * | 2016-09-28 | 2017-03-22 | 四川三和医用材料有限公司 | Medical pressure-sensitive adhesive additive |
CN109481556A (en) * | 2018-12-19 | 2019-03-19 | 河南医学高等专科学校 | For treating medicament of burn and scald and preparation method thereof in a kind of clinical care |
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Cited By (3)
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CN106512069A (en) * | 2016-09-28 | 2017-03-22 | 四川三和医用材料有限公司 | Medical pressure-sensitive adhesive anti-inflammatory and bactericidal additive |
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CN109481556A (en) * | 2018-12-19 | 2019-03-19 | 河南医学高等专科学校 | For treating medicament of burn and scald and preparation method thereof in a kind of clinical care |
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