CN108042702A - A kind of sedate tranquilizing the mind beverage and preparation method thereof - Google Patents
A kind of sedate tranquilizing the mind beverage and preparation method thereof Download PDFInfo
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- CN108042702A CN108042702A CN201711392503.8A CN201711392503A CN108042702A CN 108042702 A CN108042702 A CN 108042702A CN 201711392503 A CN201711392503 A CN 201711392503A CN 108042702 A CN108042702 A CN 108042702A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
A kind of sedate tranquilizing the mind beverage, is made of the raw material of following proportion by weight：Ginseng 10 30, PORIA ALBA 5 20, White God 5 20, Radix Polygalae 5 20, Rhizoma Atractylodis Macrocephalae 5 20, grass-leaved sweetflag 5 20, spina date seed 5 20, the tuber of dwarf lilyturf 5 20, cow-bezoar 5 20, cinnabar 20 40.There is the present invention calming heart to protect god, and beneficial blood controlling nocturnal emission with astringent drugs strengthens the strong will of power, and clear three is burnt, and resolving sputum saliva brings up the mind, reinforce vital energy and other effects, dry throat is cured mainly, is palpitated with fear, palpitation, forgetful etc..The present invention can improve the sleep of people, can guarantee that people normally sleep, and can improve people’s lives quality, avoid the generation of insomnia phenomenon.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of sedate tranquilizing the mind beverage and preparation method thereof.
Background technology
With the fast development of economic society, the continuous quickening of rhythm of life.Insomnia mostly occurs among people from workplace, often
All it is that operating pressure is too big, caused by psychology puts upon the full stretch.Epidemiology survey shows that insomnia incidence is in the U.S.
33%, it is 4%-22% in Europe, 10%-20% is also up in China.This phrenoblabia will have been seriously affected in workplace
The normal life of white collar, its very important presence.
The time in life there are about 1/3rd of people is spent in sleep, and normal sleep is to ensure human lives' matter
An important factor for amount, physically and mentally healthy and work efficiency.But with the development of society, the quickening of modern life rhythm and life style
Change, insomnia phenomenon generally occurs caused by a variety of causes, and the incidence of insomnia is in ascendant trend year by year.Therefore, have a sleepless night
Through becoming a kind of social problem, almost everyone all at fault dormancy experience or received sleep insufficiency and bring
It influences.
The content of the invention
The technical problems to be solved by the invention be in view of the deficiencies of the prior art, provide it is a kind of it is in good taste, can improve and sleep
It sleeps, improves sedate tranquilizing the mind beverage of people's quality of life and preparation method thereof.
The technical problems to be solved by the invention are realized by following technical solution.A kind of sedate, which is calmed the nerves, to be drunk
Material, its main feature is that, it is made of the raw material of following proportion by weight：Ginseng 10-30, PORIA ALBA 5-20, White God 5-20, Radix Polygalae 5-
20, Rhizoma Atractylodis Macrocephalae 5-20, grass-leaved sweetflag 5-20, spina date seed 5-20, tuber of dwarf lilyturf 5-20, cow-bezoar 5-20, cinnabar 20-40, its preparation method are：
(1) extract：Raw material is weighed by above-mentioned parts by weight, adds the distilled water heating and refluxing extraction of 6-10 times of content of starting materials parts by weight, 2-3 times,
Each 2-3h；(2) concentrate：Filtrate is obtained after filtering, is concentrated under reduced pressure under conditions of 55-65 DEG C ,-0.1-- 0.08Mpa, it is dense
Solid content 8-11% is reduced to, obtains medicinal material concentrate；(3) alcohol precipitation：Ethyl alcohol is added into the medicinal material concentrate of step (2),
Concentration of alcohol is made to reach 50-70%, when standing 18-24 is small, supernatant is taken to be concentrated under reduced pressure into solid content 20-25%, is obtained
Supernatant concentration liquid；(4) allocate：Supernatant concentration liquid 40-50g is taken, adds in white granulated sugar 20-30g, citric acid 1-3g, carragheen
0.1-0.3g mixings add distilled water to supply parts by weight to 100g, and the high-temperature sterilization after 0.45 μm of membrane filtration is filling to make
.
Preferably, it is made of the raw material of following proportion by weight：Ginseng 10, PORIA ALBA 5, White God 5, Radix Polygalae 5, Rhizoma Atractylodis Macrocephalae 5,
Grass-leaved sweetflag 5, spina date seed 5, the tuber of dwarf lilyturf 5, cow-bezoar 5, cinnabar 20.
Preferably, it is made of the raw material of following proportion by weight：Ginseng 30, PORIA ALBA 20, White God 20, Radix Polygalae 20, in vain
Art 20, grass-leaved sweetflag 20, spina date seed 20, the tuber of dwarf lilyturf 20, cow-bezoar 20, cinnabar 40.
Preferably, it is made of the raw material of following proportion by weight：Ginseng 15, PORIA ALBA 10, White God 10, Radix Polygalae 10, in vain
Art 10, grass-leaved sweetflag 10, spina date seed 10, the tuber of dwarf lilyturf 10, cow-bezoar 10, cinnabar 25.
Preferably, it is concentrated under reduced pressure in the step (2) under conditions of 60 DEG C, -0.09Mpa.
Preferably, the step (3) adds in white granulated sugar 25g, citric acid 2g, carragheen 0.2g.
Compared with prior art, there is the present invention calming heart to protect god, and beneficial blood controlling nocturnal emission with astringent drugs strengthens the strong will of power, and clear three is burnt, and resolving sputum saliva is educated
Nourishing the heart to keep a sound mind, reinforce vital energy and other effects, dry throat is cured mainly, is palpitated with fear, palpitation, forgetful etc..The present invention can improve the sleep of people, can guarantee
People normally sleep, and can improve people’s lives quality, avoid the generation of insomnia phenomenon.
Specific embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in the embodiment of the present invention
Technical solution is clearly and completely described, it is clear that and described embodiment is only part of the embodiment of the present invention, without
It is whole embodiments.
Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without making creative work
The every other embodiment obtained, belongs to the scope of protection of the invention.
A kind of embodiment 1, sedate tranquilizing the mind beverage, is made of the raw material of following proportion by weight：Ginseng 10-30, PORIA ALBA
5-20, White God 5-20, Radix Polygalae 5-20, Rhizoma Atractylodis Macrocephalae 5-20, grass-leaved sweetflag 5-20, spina date seed 5-20, tuber of dwarf lilyturf 5-20, cow-bezoar 5-20,
Cinnabar 20-40, its preparation method are：(1) extract：Raw material is weighed by above-mentioned parts by weight, adds the steaming of 6-10 times of content of starting materials parts by weight
Distilled water heating and refluxing extraction, 2-3 times, each 2-3h；(2) concentrate：Obtain filtrate after filtering, 55-65 DEG C ,-0.1--
It is concentrated under reduced pressure under conditions of 0.08Mpa, is concentrated into solid content 8-11%, obtain medicinal material concentrate；(3) alcohol precipitation：To step
(2) ethyl alcohol is added in medicinal material concentrate, concentration of alcohol is made to reach 50-70%, when standing 18-24 is small, takes supernatant decompression dense
Solid content 20-25% is reduced to, obtains supernatant concentration liquid；(4) allocate：Supernatant concentration liquid 40-50g is taken, adds in white sand
Sugared 20-30g, citric acid 1-3g, carragheen 0.1-0.3g mixings add distilled water to supply parts by weight to 100g, through 0.45 μm of filter membrane
High-temperature sterilization after filtering, it is filling to can be prepared by.The spina date seed, time of the year when autumn changes into winter harvesting ripening fruits, removes pulp and nucleocapsid, receives
Collect seed, dry.Its property is sweet, sour, puts down.Enter liver, courage, the heart channel of Hang-Shaoyin.Major function：Tonifying liver, calming heart, arrest sweating promote the production of body fluid.Spina date seed is being pacified
The opinion that god, insomnia field have its original, and it is evident in efficacy, by doctor patient's laudatory title " sleeping fruit in east ".The classic of TCM《Legendary god of farming's sheet
Grass warp》In it is on the books very early, wild jujube can " five viscera settling, macrobiosis of making light of one's life by commiting suicide ".So must not look down upon this wild fruit, it has
There is very big medical value, nourishing the liver, calming heart, tranquilizing the mind, arrest sweating can be played the role of.It is medically commonly used to decline to treat nerve
Weak, vexed insomnia, dreaminess, night sweat, easily frightened etc. diseases.Meanwhile and certain strengthening by means of tonics effect can be reached.Chinese medicine " stable soup ",
It is exactly using spina date seed as made of main component.The bright spina date seed of modern study table benevolence has significant sedative-hypnotic effect, to animal
Spontaneous activity or passive activity have apparent inhibitory action.Spina date seed water decoction is gavaged or is injected intraperitoneally, no matter daytime or
Night, normal condition or caffeine excitatory state, also show as tranquilizing soporific effect.The Rhizoma Atractylodis Macrocephalae is fried；Radix Polygalae removes the heart.
Embodiment 2 in the sedate tranquilizing the mind beverage according to embodiment 1, is made of the raw material of following proportion by weight：People
Ginseng 10, PORIA ALBA 5, White God 5, Radix Polygalae 5, Rhizoma Atractylodis Macrocephalae 5, grass-leaved sweetflag 5, spina date seed 5, the tuber of dwarf lilyturf 5, cow-bezoar 5, cinnabar 20.
Embodiment 3, in the sedate tranquilizing the mind beverage according to embodiment 1 or 2, by the raw material group of following proportion by weight
Into：Ginseng 30, PORIA ALBA 20, White God 20, Radix Polygalae 20, Rhizoma Atractylodis Macrocephalae 20, grass-leaved sweetflag 20, spina date seed 20, the tuber of dwarf lilyturf 20, cow-bezoar 20,
Cinnabar 40.
Embodiment 4, in the sedate tranquilizing the mind beverage according to embodiment 1 or 2 or 3, by the raw material of following proportion by weight
Composition：Ginseng 15, PORIA ALBA 10, White God 10, Radix Polygalae 10, Rhizoma Atractylodis Macrocephalae 10, grass-leaved sweetflag 10, spina date seed 10, the tuber of dwarf lilyturf 10, cow-bezoar
10, cinnabar 25.
Embodiment 5, according in embodiment 1-4 any one of them sedate tranquilizing the mind beverages, in the step (2) 60 DEG C ,-
It is concentrated under reduced pressure under conditions of 0.09Mpa.
Embodiment 6, according in embodiment 1-5 any one of them sedate tranquilizing the mind beverages, the step (3) adds in white granulated sugar
25g, citric acid 2g, carragheen 0.2g.
Embodiment 7, according in embodiment 1-6 any one of them sedate tranquilizing the mind beverages, its preparation method is：(1) extract：
Raw material is weighed by above-mentioned parts by weight, adds the distilled water heating and refluxing extraction of 6-10 times of content of starting materials parts by weight, 3 times, each 3h；(2)
Concentration：Filtrate is obtained after filtering, is concentrated under reduced pressure under conditions of 60 DEG C, -0.09Mpa, is concentrated into solid content 10%, is obtained
To medicinal material concentrate；(3) alcohol precipitation：Ethyl alcohol is added into the medicinal material concentrate of step (2), concentration of alcohol is made to reach 60%, is stood
21 it is small when, supernatant is taken to be concentrated under reduced pressure into solid content 23%, obtains supernatant concentration liquid；(4) allocate：Take supernatant concentration
Liquid 45g, adds in white granulated sugar 25g, citric acid 2g, and carragheen 0.2g mixings add distilled water to supply parts by weight to 100g, through 0.45 μm
High-temperature sterilization after membrane filtration, it is filling to can be prepared by.
A kind of sedate tranquilizing the mind beverage provided by the present invention and preparation method thereof is described in detail above, herein
It applies specific case to be set forth the principle of the present invention and embodiment, the explanation of above example is only intended to help
Understand the method and its core concept of the present invention；Meanwhile for those of ordinary skill in the art, thought according to the invention,
There will be changes in specific embodiments and applications, in conclusion this specification content should not be construed as to this
The limitation of invention.
Finally it should be noted that：The foregoing is only a preferred embodiment of the present invention, is not intended to limit the invention,
Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, still may be used
To modify to the technical solution recorded in foregoing embodiments or carry out equivalent substitution to which part technical characteristic,
Within the spirit and principles of the invention, any modifications, equivalent replacements and improvements are made should be included in the present invention's
Within protection domain.
Claims (6)
1. a kind of sedate tranquilizing the mind beverage, which is characterized in that be made of the raw material of following proportion by weight：Ginseng 10-30, PORIA ALBA
5-20, White God 5-20, Radix Polygalae 5-20, Rhizoma Atractylodis Macrocephalae 5-20, grass-leaved sweetflag 5-20, spina date seed 5-20, tuber of dwarf lilyturf 5-20, cow-bezoar 5-20,
Cinnabar 20-40,
Its preparation method is：
(1) extract：Raw material is weighed by above-mentioned parts by weight, adds the distilled water heating and refluxing extraction of 6-10 times of content of starting materials parts by weight, 2-3
It is secondary, each 2-3h；
(2) concentrate：Filtrate is obtained after filtering, is concentrated under reduced pressure, is concentrated under conditions of 55-65 DEG C ,-0.1-- 0.08Mpa
Solid content 8-11% obtains medicinal material concentrate；
(3) alcohol precipitation：Ethyl alcohol is added into the medicinal material concentrate of step (2), concentration of alcohol is made to reach 50-70%, it is small to stand 18-24
When, supernatant is taken to be concentrated under reduced pressure into solid content 20-25%, obtains supernatant concentration liquid；
(4) allocate：Supernatant concentration liquid 40-50g is taken, adds in white granulated sugar 20-30g, citric acid 1-3g, carragheen 0.1-0.3g are mixed
It is even, distilled water is added to supply parts by weight to 100g, the high-temperature sterilization after 0.45 μm of membrane filtration is filling to can be prepared by.
2. a kind of sedate tranquilizing the mind beverage according to claim 1, which is characterized in that by the raw material group of following proportion by weight
Into：Ginseng 10, PORIA ALBA 5, White God 5, Radix Polygalae 5, Rhizoma Atractylodis Macrocephalae 5, grass-leaved sweetflag 5, spina date seed 5, the tuber of dwarf lilyturf 5, cow-bezoar 5, cinnabar 20.
3. a kind of sedate tranquilizing the mind beverage according to claim 1, which is characterized in that by the raw material group of following proportion by weight
Into：Ginseng 30, PORIA ALBA 20, White God 20, Radix Polygalae 20, Rhizoma Atractylodis Macrocephalae 20, grass-leaved sweetflag 20, spina date seed 20, the tuber of dwarf lilyturf 20, cow-bezoar 20,
Cinnabar 40.
4. a kind of sedate tranquilizing the mind beverage according to claim 1, which is characterized in that by the raw material group of following proportion by weight
Into：Ginseng 15, PORIA ALBA 10, White God 10, Radix Polygalae 10, Rhizoma Atractylodis Macrocephalae 10, grass-leaved sweetflag 10, spina date seed 10, the tuber of dwarf lilyturf 10, cow-bezoar 10,
Cinnabar 25.
5. a kind of sedate tranquilizing the mind beverage according to claim 1, it is characterised in that：In the step (2) 60 DEG C ,-
It is concentrated under reduced pressure under conditions of 0.09Mpa.
6. a kind of sedate tranquilizing the mind beverage according to claim 1, it is characterised in that：The step (3) adds in white granulated sugar
25g, citric acid 2g, carragheen 0.2g.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711392503.8A CN108042702A (en) | 2017-12-21 | 2017-12-21 | A kind of sedate tranquilizing the mind beverage and preparation method thereof |
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| CN201711392503.8A CN108042702A (en) | 2017-12-21 | 2017-12-21 | A kind of sedate tranquilizing the mind beverage and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103005556A (en) * | 2012-12-18 | 2013-04-03 | 段海庆 | Beverage |
| CN104042906A (en) * | 2014-06-20 | 2014-09-17 | 任新年 | Nerve-calming intelligence-developing traditional Chinese medicine oral liquid and preparation method thereof |
-
2017
- 2017-12-21 CN CN201711392503.8A patent/CN108042702A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103005556A (en) * | 2012-12-18 | 2013-04-03 | 段海庆 | Beverage |
| CN104042906A (en) * | 2014-06-20 | 2014-09-17 | 任新年 | Nerve-calming intelligence-developing traditional Chinese medicine oral liquid and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典临床用药须知 中药饮片卷 2015年版》", 31 October 2017, 中国医药科技出版社 * |
| 孙世发: "《中华医方 内科篇 心系病》", 31 March 2015, 科学技术文献出版社 * |
| 彭成编: "《中药毒理学》", 30 April 2014, 中国中医药出版社 * |
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