CN108030859A - It is a kind of to be used to treat Chinese medicine preparation of cardiovascular and cerebrovascular disease and preparation method thereof - Google Patents
It is a kind of to be used to treat Chinese medicine preparation of cardiovascular and cerebrovascular disease and preparation method thereof Download PDFInfo
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract
The present invention provides a kind of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease and preparation method thereof, the Chinese medicine preparation that the present invention is used to treat cardiovascular and cerebrovascular disease is prepared using special component and usage ratio, being capable of tonifying Qi complement, promote blood flow, the generation of deposit in blood is reduced, effectively treats all kinds of cardiovascular and cerebrovascular diseases.The preparation method technique that the present invention is used for the Chinese medicine preparation for treating cardiovascular and cerebrovascular disease is simple, for different can need that different dosage forms product is prepared, suitable for large-scale production.
Description
Technical field
The present invention relates to field of traditional Chinese, in particular to a kind of Chinese medicine system for being used to treat cardiovascular and cerebrovascular disease
Agent and preparation method thereof.
Background technology
Cardiovascular and cerebrovascular disease is the general designation of cardiovascular and cranial vascular disease, is referred to since hyperlipidemia, blood are sticky, dynamic
The ischemic or hemorrhagic disease that heart, brain and body tissue caused by pulse atherosclerosis, hypertension etc. occur.Heart and brain blood
Pipe disease is a kind of serious threat mankind, particularly the common disease of more than 50 years old middle-aged and elderly people's health, has high illness rate, high cause
, even if the treatment means that application is most advanced, perfect at present, can still there be more than 50% cerebrovascular in the characteristics of residual rate and high mortality
It is unexpected that survivor's life cannot take care of oneself completely, and the number that cardiovascular and cerebrovascular disease is died of in the whole world every year is up to 15,000,000 people, occupy each
The kind cause of the death is the first.
In correlation technique, doctor trained in Western medicine is often first aid class medicine to the medicine of cardiovascular and cerebrovascular disease, such as nitroglycerin class
Medicine and Digitalis extract etc., are worked by the way of blood vessel is expanded, but this mode cannot fundamentally treat heart and brain blood
Pipe disease, drug effect cannot continue for a long time, and blood vessel can also be shunk, and patient can only rely on medicine, and long-time service may also produce anti-medicine
Property.When vasodilator drug is invalid, cardiac stent, bridging and pacemaker operation can only be just done, blood vessel can constantly produce new
Block, it is necessary to constantly do new operation, but human body is limited to the ability to bear of operation.Doctor trained in Western medicine is to cerebral infarction using thrombolysis
Method is treated, but thrombolysis be easy to cause cerebral hemorrhage, and cerebral hemorrhage is treated using the method for hemostasis, but hemostasis can produce cerebral infarction, when
After cerebral infarction and cerebral hemorrhage occur at the same time, treatment of just having no idea.Related traditional Chinese medicine preparation product, often using promoting blood circulation and removing blood stasis and
Limited tonifying Qi, has cardiovascular and cerebrovascular diseases certain alleviation effect, but therapeutic effect is limited, it is impossible to cures, comes for the traditional Chinese medical science completely
Say, cardiovascular and cerebrovascular disease falls within incurable disease at present.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, and described is used for
Treat cardiovascular and cerebrovascular disease Chinese medicine preparation can tonifying Qi complement, promote blood flow, reduce blood in deposit generation, have
Effect treats all kinds of cardiovascular and cerebrovascular diseases.
The second object of the present invention is to provide a kind of system for being used to treat the Chinese medicine preparation of cardiovascular and cerebrovascular disease
Preparation Method, this method technique is simple, for different can need that different dosage forms product is prepared, suitable for large-scale production.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme：
A kind of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, is mainly prepared by the component of following mass fraction：
2-6 parts of ginseng, 2-4 parts of the dried rhizome of rehmannia, 3-7 parts of Schisandra chinensis, 3-7 parts of spina date seed, 2-6 parts of Poria cocos, 2-6 parts of the coptis, ophiopogon
3-7 parts of 2-6 parts, 1-3 parts of west safflower, 2-6 parts of radix scrophulariae, 2-6 parts of Radix Salviae Miltiorrhizae, 2-6 parts of asparagus fern, 3-7 parts of the seed of Oriental arborvitae and Angelica sinensis.
Preferably, mainly it is prepared by the component of following mass fraction：
3-5 parts of ginseng, 2-3 parts of the dried rhizome of rehmannia, 4-6 parts of Schisandra chinensis, 4-6 parts of spina date seed, 3-5 parts of Poria cocos, 3-5 parts of the coptis, ophiopogon
4-6 parts of 3-5 parts, 1-2 parts of west safflower, 3-5 parts of radix scrophulariae, 3-5 parts of Radix Salviae Miltiorrhizae, 3-5 parts of asparagus fern, 4-6 parts of the seed of Oriental arborvitae and Angelica sinensis.
It is further preferred that mainly it is prepared by the component of following mass fraction：
4 parts of ginseng, 3 parts of the dried rhizome of rehmannia, 5 parts of Schisandra chinensis, 5 parts of spina date seed, 4 parts of Poria cocos, 4 parts of the coptis, 4 parts of ophiopogon, west safflower 2
5 parts of part, 4 parts of radix scrophulariae, 4 parts of Radix Salviae Miltiorrhizae, 4 parts of asparagus fern, 5 parts of the seed of Oriental arborvitae and Angelica sinensis.
Alternatively, the Chinese medicine preparation includes the one or more in pulvis, tablet, pill and capsule.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
Each raw material is weighed in proportion, is crushed after mixing, is obtained powder product.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
Each raw material is weighed in proportion, is crushed after mixing, and gained powder is uniformly mixed with bonding auxiliary material, pill is prepared
Product.
Alternatively, the bonding auxiliary material includes the one or more in water, honey, beeswax, rice flour, rice paste and batter.
Alternatively, the dosage of the bonding auxiliary material is the 10%-25% of powder quality, is preferably 15%-20%, further
Preferably 15%.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
Alternatively, the weight of the pill is 0.2-0.6g, is preferably 0.3-0.5g, more preferably 0.4g.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule, bag
Include：
Each raw material is weighed in proportion, is crushed after mixing, gained is powder filled in capsule shells, obtain capsule product.
Alternatively, the capsule shells include hard rubber softgel shell and/or soft capsule shells.
Alternatively, the content of dispersion in single capsule is 0.2-0.6g, is preferably 0.2-0.4g, more preferably 0.4g.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
Compared with prior art, beneficial effects of the present invention are：
The Chinese medicine preparation that the present invention is used to treat cardiovascular and cerebrovascular disease is prepared using special component and usage ratio, energy
Enough tonifying Qi complements, promote blood flow, and reduce the generation of deposit in blood, effectively treat all kinds of cardiovascular and cerebrovascular diseases.This hair
The preparation method technique of the bright Chinese medicine preparation for treating cardiovascular and cerebrovascular disease is simple, can be directed to different needs and be prepared not
Same dosage form product, suitable for large-scale production.
Embodiment
Technical scheme is clearly and completely described below in conjunction with embodiment, but ability
Field technique personnel will be understood that following described embodiment is part of the embodiment of the present invention, instead of all the embodiments,
The present invention is merely to illustrate, and is not construed as limiting the scope of the invention.Based on the embodiments of the present invention, the common skill in this area
Art personnel all other embodiments obtained without making creative work, belong to the model that the present invention protects
Enclose.The person that is not specified actual conditions in embodiment, the condition suggested according to normal condition or manufacturer carry out.Agents useful for same or instrument
Production firm person is not specified, is the conventional products that can be obtained by commercially available purchase.
A kind of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, is mainly prepared by the component of following mass fraction：
2-6 parts of ginseng, 2-4 parts of the dried rhizome of rehmannia, 3-7 parts of Schisandra chinensis, 3-7 parts of spina date seed, 2-6 parts of Poria cocos, 2-6 parts of the coptis, ophiopogon
3-7 parts of 2-6 parts, 1-3 parts of west safflower, 2-6 parts of radix scrophulariae, 2-6 parts of Radix Salviae Miltiorrhizae, 2-6 parts of asparagus fern, 3-7 parts of the seed of Oriental arborvitae and Angelica sinensis.
The Chinese medicine preparation that the present invention is used to treat cardiovascular and cerebrovascular disease is prepared using special component and usage ratio, energy
Enough tonifying Qi complements, promote blood flow, and reduce the generation of deposit in blood, effectively treat all kinds of cardiovascular and cerebrovascular diseases.
The fleshy root of ginseng is strong tonic, nature and flavor：Sweet in flavor, slight bitter, it is warm-natured, flat.Returns spleen, lung channel, the heart channel of Hang-Shaoyin.Tonifying Qi,
Prevent prolapse, promotes the production of body fluid, and calms the nerves, intelligence development.Enter spleen, lung channel.
The dried rhizome of rehmannia (Classification system：Rehmannia glutinosa Libosch), alias radix rehmanniae recen, wild country is yellow, mountain cigarette root
Deng clearing heat and cooling blood, yin-nourishing, promotes the production of body fluid.Nature and flavor：It is sweet, tremble with fear.The thoughts of returning home, liver, kidney channel.
Schisandra chinensis, has the effect of convergence astringent method, nourishing generate fluid, kidney calming.It is sour, sweet, it is warm-natured.Return lung, the heart, kidney
Through.
Spina date seed, nature and flavor：Sweet and neutral.Channel tropism：The heart channel of Hang-Shaoyin；The spleen channel；Liver Channel；Gallbladder channel.Function：Antitoxic heart-soothing and sedative；Nourishing the liver；Arrest sweating.
Poria cocos, it is sweet in flavor, light, it is mild-natured.The thoughts of returning home, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.
The coptis, there is the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.Bitter, it is cold in nature, it is nontoxic, enter the heart channel of Hang-Shaoyin.
Ophiopogon, the effect for have quench one's thirst of promoting the production of body fluid, moistening the lung and relieve the cough.Sweet in flavor, slight bitter, cold nature, returns stomach, lung, the heart channel of Hang-Shaoyin.
West safflower, has the effect of promoting blood circulation and removing blood stasis, removing pattogenic heat from the blood and toxic material from the body, resolving stagnation for tranquilization.It is sweet in flavor, it is mild-natured.Converge to heart and liver channels.
Radix scrophulariae, bitter is salty, cold nature, nontoxic, enters kidney channel.Clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass.
The effect of Radix Salviae Miltiorrhizae, has promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.Bitter, is slightly cold.The thoughts of returning home, liver
Through.
Asparagus fern, cold in nature, sweet in flavor, slight bitter.With replenishing the vital essence and removing heat, the effect of moistening lung nourshing kidney.Return lung, kidney, stomach, large intestine channel.
The effect of seed of Oriental arborvitae, has mental-tranquilization, relaxes bowel, hidroschesis.It is sweet in flavor, it is mild-natured.The thoughts of returning home, kidney, large intestine channel.
Angelica sinensis, has the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation.Nature and flavor：It is sweet, pungent, warm, Return liver, the heart, the spleen channel.
Preferably, mainly it is prepared by the component of following mass fraction：
3-5 parts of ginseng, 2-3 parts of the dried rhizome of rehmannia, 4-6 parts of Schisandra chinensis, 4-6 parts of spina date seed, 3-5 parts of Poria cocos, 3-5 parts of the coptis, ophiopogon
4-6 parts of 3-5 parts, 1-2 parts of west safflower, 3-5 parts of radix scrophulariae, 3-5 parts of Radix Salviae Miltiorrhizae, 3-5 parts of asparagus fern, 4-6 parts of the seed of Oriental arborvitae and Angelica sinensis.
It is further preferred that mainly it is prepared by the component of following mass fraction：
4 parts of ginseng, 3 parts of the dried rhizome of rehmannia, 5 parts of Schisandra chinensis, 5 parts of spina date seed, 4 parts of Poria cocos, 4 parts of the coptis, 4 parts of ophiopogon, west safflower 2
5 parts of part, 4 parts of radix scrophulariae, 4 parts of Radix Salviae Miltiorrhizae, 4 parts of asparagus fern, 5 parts of the seed of Oriental arborvitae and Angelica sinensis.
Using specified raw material consumption proportion, help to further improve tonifying Qi complement effect of gained Chinese medicine preparation, promote
Blood flow, reduces the generation of deposit in blood.
Alternatively, the Chinese medicine preparation includes the one or more in pulvis, tablet, pill and capsule.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
Each raw material is weighed in proportion, is crushed after mixing, is obtained powder product.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
Specified particle diameter is crushed to, contributes to each component to be fully absorbed by the body, further improves effect.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
Each raw material is weighed in proportion, is crushed after mixing, and gained powder is uniformly mixed with bonding auxiliary material, pill is prepared
Product.
Alternatively, the bonding auxiliary material includes the one or more in water, honey, beeswax, rice flour, rice paste and batter.
Alternatively, the dosage of the bonding auxiliary material is the 10%-25% of powder quality, is preferably 15%-20%, further
Preferably 15%.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
Alternatively, the weight of the pill is 0.2-0.6g, is preferably 0.3-0.5g, more preferably 0.4g.
A kind of preparation method for the Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule, bag
Include：
Each raw material is weighed in proportion, is crushed after mixing, gained is powder filled in capsule shells, obtain capsule product.
Alternatively, the capsule shells include hard rubber softgel shell and/or soft capsule shells.
Alternatively, the content of dispersion in single capsule is 0.2-0.6g, is preferably 0.2-0.4g, more preferably 0.4g.
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably
500 mesh.
Embodiment 1
A kind of preparation method for the Chinese medicine powder for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
2 parts of ginseng, 4 parts of the dried rhizome of rehmannia, 3 parts of Schisandra chinensis, 7 parts of spina date seed, 2 parts of Poria cocos, 6 parts of the coptis, ophiopogon 2 are weighed in proportion
3 parts of part, 3 parts of west safflower, 2 parts of radix scrophulariae, 6 parts of Radix Salviae Miltiorrhizae, 2 parts of asparagus fern, 7 parts of the seed of Oriental arborvitae and Angelica sinensis, crushed 500 mesh sieves after mixing,
Obtain powder product.
Embodiment 2
A kind of preparation method for the Chinese medicine powder for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
6 parts of ginseng, 2 parts of the dried rhizome of rehmannia, 7 parts of Schisandra chinensis, 3 parts of spina date seed, 6 parts of Poria cocos, 2 parts of the coptis, ophiopogon 6 are weighed in proportion
7 parts of part, 1 part of west safflower, 6 parts of radix scrophulariae, 2 parts of Radix Salviae Miltiorrhizae, 6 parts of asparagus fern, 3 parts of the seed of Oriental arborvitae and Angelica sinensis, crushed 800 mesh sieves after mixing,
Obtain powder product.
Embodiment 3
A kind of preparation method for the Chinese medicine powder for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
3 parts of ginseng, 2 parts of the dried rhizome of rehmannia, 6 parts of Schisandra chinensis, 6 parts of spina date seed, 3 parts of Poria cocos, 3 parts of the coptis, ophiopogon 5 are weighed in proportion
4 parts of part, 2 parts of west safflower, 3 parts of radix scrophulariae, 3 parts of Radix Salviae Miltiorrhizae, 5 parts of asparagus fern, 6 parts of the seed of Oriental arborvitae and Angelica sinensis, crushed 600 mesh sieves after mixing,
Obtain powder product.
Embodiment 4
A kind of preparation method for the Chinese medicine powder for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
5 parts of ginseng, 3 parts of the dried rhizome of rehmannia, 4 parts of Schisandra chinensis, 4 parts of spina date seed, 5 parts of Poria cocos, 5 parts of the coptis, ophiopogon 3 are weighed in proportion
6 parts of part, 1 part of west safflower, 5 parts of radix scrophulariae, 5 parts of Radix Salviae Miltiorrhizae, 3 parts of asparagus fern, 4 parts of the seed of Oriental arborvitae and Angelica sinensis, crushed 700 mesh sieves after mixing,
Obtain powder product.
Embodiment 5
A kind of preparation method for the Chinese medicine powder for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pulvis, including：
4 parts of ginseng, 3 parts of the dried rhizome of rehmannia, 5 parts of Schisandra chinensis, 5 parts of spina date seed, 4 parts of Poria cocos, 4 parts of the coptis, ophiopogon 4 are weighed in proportion
5 parts of part, 2 parts of west safflower, 4 parts of radix scrophulariae, 4 parts of Radix Salviae Miltiorrhizae, 4 parts of asparagus fern, 5 parts of the seed of Oriental arborvitae and Angelica sinensis, crushed 500 mesh sieves after mixing,
Obtain powder product.
Embodiment 6
A kind of preparation method for the medicine pill for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
1 gained powder of embodiment is uniformly mixed with accounting for the honey of powder quality 5% and accounting for the water of powder quality 5%, is adopted
Machined to obtain the pellet product that weight is 0.2g with pill.
Embodiment 7
A kind of preparation method for the medicine pill for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
2 gained powder of embodiment is uniformly mixed with accounting for the honey of powder quality 15% and accounting for the water of powder quality 10%,
Pill is used to machine to obtain pellet product of the weight for 0.6g.
Embodiment 8
A kind of preparation method for the medicine pill for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
By the honey for accounting for powder quality 10% and the water for accounting for powder quality 5% of 3 gained powder of embodiment and powder quality
Uniformly mixing, uses pill to machine to obtain weight as 0.3 pellet product.
Embodiment 9
A kind of preparation method for the medicine pill for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
4 gained powder of embodiment is uniformly mixed with accounting for the honey of powder quality 10% and accounting for the water of powder quality 10%,
Pill is used to machine to obtain pellet product of the weight for 0.5g.
Embodiment 10
A kind of preparation method for the medicine pill for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the pill, including：
5 gained powder of embodiment is uniformly mixed with accounting for the honey of powder quality 10% and accounting for the water of powder quality 5%, is adopted
Machined to obtain the pellet product that weight is 0.4g with pill.
Embodiment 11
A kind of preparation method for the Chinese medicine capsules for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule,
Including：
1 gained powder of embodiment is filled into capsule shells, the loading in single capsule is 0.2g, obtains capsule production
Product.
Embodiment 12
A kind of preparation method for the Chinese medicine capsules for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule,
Including：
2 gained powder of embodiment is filled into capsule shells, the loading in single capsule is 0.6g, obtains capsule production
Product.
Embodiment 13
A kind of preparation method for the Chinese medicine capsules for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule,
Including：
3 gained powder of embodiment is filled into capsule shells, the loading in single capsule is 0.2g, obtains capsule production
Product.
Embodiment 14
A kind of preparation method for the Chinese medicine capsules for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule,
Including：
4 gained powder of embodiment is filled into capsule shells, the loading in single capsule is 0.3g, obtains capsule production
Product.
Embodiment 15
A kind of preparation method for the Chinese medicine capsules for being used to treat cardiovascular and cerebrovascular disease, the preparation method of the capsule,
Including：
5 gained powder of embodiment is filled into capsule shells, the loading in single capsule is 0.4g, obtains capsule production
Product.
Clinic trial is carried out using 5 gained powder product of embodiment, tries out amount as everyone 2g, each trier is respectively on probation
2h is into the security inspection such as promoting circulation of blood, urine, feces routine inspection and the heart, Liver and kidney function after preceding and on probation, and the results are shown in Table 1.
The security inspection interpretation of result (t inspections) such as 1 blood of table (X ± SD), urine, feces routine inspection and the heart, Liver and kidney function
It can be seen from Table 1 that Chinese medicine preparation of the present invention clinic trial observation in, do not find obvious adverse reaction and
Toxic side effect, shows that Chinese medicine preparation of the present invention is safe and reliable.
The recommendation of Chinese medicine preparation of the present invention is grown up daily effective ingredient consumption as 2g or so, by taking 5 pulvis of embodiment as an example, adopts
Dosage amplification test is carried out with mouse, the results showed that, to be grown up, daily effective ingredient consumption is calculated as 2g, when being amplified to 630 times,
Obvious adverse reaction and toxic side effect are not found yet, fully show that Chinese medicine preparation of the present invention is safe and reliable, can be in actual use
Appropriate increase dosage as needed, to play more preferable therapeutic effect.
Taking pulvis obtained by 1-5 of the embodiment of the present invention to carry out blood circulation respectively improves experiment, measures blood flow velocity and blood
The change of flow；The measure of blood flow uses laser doppler flowmetry (FL0-N1-TWIN OMEGAWAVE limited companies
System)；The data that laser doppler flowmetry determines handle the numerical value for showing blood flow velocity and blood flow respectively by computer；
Using the man (45 years old) of health as subject, the blood flow velocity and blood flow of subject are examined before medication
(per minute to detect respectively once, to detect 20 times, be averaged altogether) is surveyed, corresponding embodiment pulvis 2g is taken afterwards, makes to be tested
Person respectively keep quite after 2h by quiet lie, and blood flow velocity and blood flow to subject are detected (per minute to detect one respectively
It is secondary, detect 20 times, be averaged altogether), everyone only carries out a pulvis of the embodiment of the present invention or comparative example test (test daily
Temperature is 26-27 DEG C, humidity 50%-60%), acquired results are as follows：
2 Chinese medicine preparation of the present invention of table improves result to blood circulation of human body
| Embodiment | Mean blood flow velocity/a.u. | Mean blood flow/a.u. |
| Embodiment 1 | 10.4 | 143 |
| Embodiment 2 | 10.5 | 145 |
| Embodiment 3 | 10.5 | 148 |
| Embodiment 4 | 10.6 | 150 |
| Embodiment 5 | 10.9 | 153 |
| Comparative example | 10 | 130 |
Note：Mean blood flow velocity and mean blood flow are the fiducial value using comparative example as radix.
It can be seen from Table 2 that blood circulation of human body, average blood flow speed can be significantly improved using Chinese medicine preparation of the present invention
Degree and mean blood flow have and substantially increase, it can be seen that and Chinese medicine preparation of the present invention is absorbed by the body by its special nature,
And blood circulation is influenced, play the role of promoting blood circulation.
Case is tried out using the typical clinical of Chinese medicine preparation of the present invention：
1st, Mr. Wang, male, 66 years old, because coronary heart disease heart puts 10 stents, large area heart infarction, produced heart failure, pericardium product afterwards
Liquid, mitral regurgitation, tricuspid regurgitation, aneurysm, induced Diabetic, hypertension, fast heart rate.Hospital has abandoned treating.Later stage
Difficulty in walking, aphonia of speaking, the only edible liquid food of 4 first quarter moons.Chinese medicine preparation of the present invention is taken first, can use sound after twenty minutes
Sound is talked, for the first time into food after 30 minutes.Chinese medicine preparation of the present invention is continuously taken, normal work can be recovered after two months
Make, symptom all disappears.
2nd, suddenly certain, man, 65 years old, taking the symptom before Chinese medicine preparation of the present invention was：Large area heart infarction, the heart walk difficulty, walk two
Ten meters will rest once, heart failure, hepatic sclerosis, but great three times, hypertension, diabetes, and lower limb fester disunion.Take
Chinese medicine preparation of the present invention can ride a bicycle 7 kilometers and buy product to company, take after two months, can take a walk after one month
Three kilometers.After taking 12 months, coronary heart disease symptom all disappears, and diabetic complication disappears, and hypertension is stablized, and hepatic sclerosis becomes
Mild fatty liver, courage enlargement reduce 1/3rd.
3rd, Chen, man, 68 years old, because myocardial acute ischemia starts to take Chinese medicine preparation of the present invention, difficulty of walking at that time,
Early retirement.After taking Chinese medicine preparation half a year of the present invention, myocardial ischemia symptom is wholly absent.
4th, field, female, 63 years old, because of myocardial acute ischemia, difficulty in walking, it is virtually impossible to work.Asked to Beijing various big hospital
It is invalid to cure, and starts to take Chinese medicine preparation of the present invention, and after taking three months, myocardial ischemia symptom is wholly absent.
5th, Guo, female, 76 years old, valvular inadequacy, hypertension took Chinese medicine preparation of the present invention 3 months, and muscle power is obvious to be increased
Add, remove examination in hospital after taking half a year, indices are normal.
6th, Shandong, man, 81 years old, bradycardia (50-52 beats/min), premature beat (5-8 beats/min).Take Chinese medicine of the present invention
After preparation 3 months, premature beat starts to be reduced to 2-3 times per minute, and bradycardia starts improvement and reaches 60 times per minute or so, takes
Chinese medicine preparation of the present invention is after 6 months, and premature beat disappears, pulse reach 68-70 times it is per minute.
7th, Mr. Wang, female, 76 years old, because heart failure did pacemaker operation, can't take care of oneself, take Chinese medicine preparation one of the present invention
Feel spiritedness energetically within a month, taking three months to get around.
8th, Lee, female, 39 years old, because pareordia is uncomfortable, emits to left forearm discomfort, and because brain blood supply is bad, sleep is poor, is afraid of
Cold, fatiguability；Chinese medicine preparation of the present invention is taken after 20 days, above-mentioned sensation and symptom have mitigated, and after taking one month, feel
Spiritedness, sleep is good, and pareordia is without any bad sensation.
9th, Liu, female, 59 years old, has genetic hypertension, diabetes, cerebral thrombus 5 years, right side limbs are not active, the frequent heart
Angina, it is weak on foot, without spirit.Take Chinese medicine preparation of the present invention after one month each broad aspect all have improvement greatly, housework is not
Feel tired, right side limbs than in the past flexibly more.
10th, model, man, 70 years old, cerebral infarction 2 months, took Chinese medicine preparation of the present invention and recovers normal after 3 months.
11st, Peng, man, 72 years old, cerebral infarction 2 years, can't take care of oneself and nursed entirely by others, take Chinese medicine preparation 6 of the present invention
Life can take care of oneself after a month.
Chinese medicine preparation of the present invention is suitable for coronary heart diseases and angina pectoris, shortness of breath uncomfortable in chest, block, myocardial ischemia, atrial fibrillation, the heart
Restrain not normal, myocardial hypertrophy, bradycardia, tachycardia, heart failure, cerebral infarction sequelae, cerebral hemorrhage sequelae, chronic myocarditis, low
Blood pressure, rheumatic heart disease, the various chronic diseases marked by deficiency of vital energy.Stent, bridging and the postoperative maintenance of pacemaker.Prevent cardiovascular and cerebrovascular diseases.
Chinese medicine preparation of the present invention has following remarkable efficacy：
(1) the effectively generation of prevention coronary heart disease and headstroke.
(2) improve myocardial ischemia rapidly, allow the walking all difficult patient that speaks to be obviously improved symptom in 5 days.
(3) can allow more than 80% severe angina pectoris patient, exempt to do stent and bypass surgery.
(4) can allow more than 80% bradycardia patient, exempt to do pacemaker operation.
(5) symptom of Patients with Cardiac Failure is improved rapidly.
(6) apoplexy hemiplegia patient is allowed to reply health rapidly.
Although being illustrated and the invention has been described with specific embodiment, but it will be appreciated that various embodiments above is only used
To illustrate technical scheme, rather than its limitations；It will be understood by those of ordinary skill in the art that：Without departing substantially from this hair
In the case of bright spirit and scope, it can modify to the technical solution described in foregoing embodiments, or to wherein
Some or all of technical characteristic carries out equivalent substitution；And these are changed or are replaced, the essence of appropriate technical solution is not made
Depart from the scope of various embodiments of the present invention technical solution；It is, therefore, intended that include belonging to the present invention in the following claims
In the range of all these substitutions and modifications.
Claims (10)
1. a kind of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease, it is characterised in that mainly by the component of following mass fraction
It is prepared：
2-6 parts of ginseng, 2-4 parts of the dried rhizome of rehmannia, 3-7 parts of Schisandra chinensis, 3-7 parts of spina date seed, 2-6 parts of Poria cocos, 2-6 parts of the coptis, ophiopogon 2-6
3-7 parts of part, 1-3 parts of west safflower, 2-6 parts of radix scrophulariae, 2-6 parts of Radix Salviae Miltiorrhizae, 2-6 parts of asparagus fern, 3-7 parts of the seed of Oriental arborvitae and Angelica sinensis.
A kind of be used to treat the Chinese medicine preparation of cardiovascular and cerebrovascular disease 2. according to claim 1, it is characterised in that mainly by
The component of following mass fraction is prepared：
3-5 parts of ginseng, 2-3 parts of the dried rhizome of rehmannia, 4-6 parts of Schisandra chinensis, 4-6 parts of spina date seed, 3-5 parts of Poria cocos, 3-5 parts of the coptis, ophiopogon 3-5
4-6 parts of part, 1-2 parts of west safflower, 3-5 parts of radix scrophulariae, 3-5 parts of Radix Salviae Miltiorrhizae, 3-5 parts of asparagus fern, 4-6 parts of the seed of Oriental arborvitae and Angelica sinensis.
A kind of be used to treat the Chinese medicine preparation of cardiovascular and cerebrovascular disease 3. according to claim 2, it is characterised in that mainly by
The component of following mass fraction is prepared：
4 parts of ginseng, 3 parts of the dried rhizome of rehmannia, 5 parts of Schisandra chinensis, 5 parts of spina date seed, 4 parts of Poria cocos, 4 parts of the coptis, 4 parts of ophiopogon, 2 parts of west safflower, member
5 parts of 4 parts of ginseng, 4 parts of Radix Salviae Miltiorrhizae, 4 parts of asparagus fern, 5 parts of the seed of Oriental arborvitae and Angelica sinensis.
4. according to a kind of any Chinese medicine preparations for being used to treat cardiovascular and cerebrovascular disease of claim 1-3, it is characterised in that
The Chinese medicine preparation includes the one or more in pulvis, tablet, pill and capsule.
5. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease as claimed in claim 4, its feature exist
In, the preparation method of the pulvis, including：
Each raw material is weighed in proportion, is crushed after mixing, is obtained powder product.
6. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease according to claim 5, its feature
It is, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably 500 mesh.
7. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease as claimed in claim 4, its feature exist
In, the preparation method of the pill, including：
Each raw material is weighed in proportion, is crushed after mixing, and gained powder is uniformly mixed with bonding auxiliary material, pill production is prepared
Product.
8. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease according to claim 7, its feature
It is, the bonding auxiliary material includes the one or more in water, honey, beeswax, rice flour, rice paste and batter；
Alternatively, the dosage of the bonding auxiliary material is the 10%-25% of powder quality, is preferably 15%-20%, further preferably
For 15%；
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably 500
Mesh；
Alternatively, the weight of the pill is 0.2-0.6g, is preferably 0.3-0.5g, more preferably 0.4g.
9. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease as claimed in claim 4, its feature exist
In, the preparation method of the capsule, including：
Each raw material is weighed in proportion, is crushed after mixing, gained is powder filled in capsule shells, obtain capsule product.
10. a kind of preparation method of Chinese medicine preparation for being used to treat cardiovascular and cerebrovascular disease according to claim 9, its feature
It is, the capsule shells include hard rubber softgel shell and/or soft capsule shells；
Alternatively, the content of dispersion in single capsule is 0.2-0.6g, is preferably 0.2-0.4g, more preferably 0.4g；
Alternatively, the grain diameter of the pulvis is less than or equal to 500 mesh, is preferably 500-800 mesh, more preferably 500
Mesh.
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| CN114306508A (en) * | 2022-01-12 | 2022-04-12 | 黑龙江乐善堂中药制剂有限公司 | Formula for dredging twelve channels and collaterals with effects of dispelling wind and removing cold and preparation method thereof |
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