CN108030811A - A kind of cancer therapy drug - Google Patents

A kind of cancer therapy drug Download PDF

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Publication number
CN108030811A
CN108030811A CN201711500395.1A CN201711500395A CN108030811A CN 108030811 A CN108030811 A CN 108030811A CN 201711500395 A CN201711500395 A CN 201711500395A CN 108030811 A CN108030811 A CN 108030811A
Authority
CN
China
Prior art keywords
parts
banyan
seed
cancer therapy
therapy drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711500395.1A
Other languages
Chinese (zh)
Inventor
李丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chongqing Nanhua Biological Technology Co Ltd
Original Assignee
Chongqing Nanhua Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chongqing Nanhua Biological Technology Co Ltd filed Critical Chongqing Nanhua Biological Technology Co Ltd
Priority to CN201711500395.1A priority Critical patent/CN108030811A/en
Publication of CN108030811A publication Critical patent/CN108030811A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

A kind of cancer therapy drug, in parts by weight, including 23 parts of 5 10 parts of banyan seed extract, 23 parts of rheum officinale, 23 parts of Teng pears root, balsamine son, 23 parts of Sculellaria barbata, 12 parts of nidus vespae.The cancer therapy drug of the present invention is preferable for the therapeutic effect of cancer, and sufficiently make use of this plant resources of banyan, it is more preferably played a role.

Description

A kind of cancer therapy drug
Technical field
The present invention relates to medical material technical field, more particularly to a kind of cancer therapy drug.
Background technology
Banyan, megaphanerophyte, up to 15-25 meters, the diameter of a cross-section of a tree trunk 1.3 meters above the ground up to 50 centimetres, extensively open up by hat width;Veteran often has rust brown aerial root.Bark Dark grey.The thin keratin of leaf, narrow ellipse, surface bottle green, glossy, full edge.The paired axillary of banyan fruit is born in branches and leaves of having fallen leaves Armpit, yellow or blush when ripe, oblate spheroid, base life bract 3 is wide avette, harbors;Male flower, female flower, gall flower are same to be born in a banyan fruit It is interior, there is a little short bristle between flower;Tapel 3, wide avette, the life of style nearside, column cap is short, stick.Achene oval.Florescence 5-6 Month.Be distributed in China, Sri Lanka, India, Burma, Thailand, Vietnam, Malaysia, Philippine, Japan, Papua it is new it is several in Sub- and Australia is until Caroline.
Banyan is syconium axillary, subsphaeroidal, at the beginning milky, and yellow or pale red when ripe, in 5~June of florescence, fruit footpath is about 0.8cm. fructescence in 9~October fruit very littles, as the bead of one one, when ripe, can be become red by green.
The ornamental value of banyan can be described as it is well known that but its nutritive value and applying upper medical value in the traditional Chinese medical science With regard to rarely known by the people.
The content of the invention
In view of this, the object of the present invention is to provide a kind of cancer therapy drug, in parts by weight, including banyan seed extracts 5-10 parts of thing, 2-3 parts of rheum officinale, 2-3 parts of Teng pears roots, 2-3 parts of balsamine son, 2-3 parts of Sculellaria barbata, 1-2 parts of nidus vespae.
Contain substantial amounts of polysaccharide in banyan seed, treatment of the polysaccharide for cancer has obvious action.
Rheum officinale, has and attacks stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, removing toxic substances and other effects;
Teng pears roots, have clearing heat and detoxicating, clearing heat and promoting diuresis, preventing tumor anticancer, dispelling wind and eliminating dampness, diuresis hemostasis, removing toxicity for detumescence, disappears Change bad, vomiting, arthralgia pain due to rheumatism, treating rheumatic ostealgia, Alimentary Tract Cancer, tumor in digestive tract, large carbuncle boil, treating rheumatic ostealgia and jaundice etc. Disease.
Sculellaria barbata, has the effect of clearing heat and detoxicating, stagnation resolvation diuresis.
Nidus vespae has anti-inflammatory effect, while can also adjust mouthfeel.
The Second Problem that the present invention solves is the processing method of cancer therapy drug, is comprised the following steps:
(1) banyan seed is taken, grind into powder, then sieves banyan powder of seeds, and then being flowed back with petroleum ether removes fat Soluble substance and impurity, then with 95% alcohol reflux, slough chlorophyll and alcohol-soluble small-molecule substance, banyan seed is obtained after drying Crude extract;
(2) crude extract of banyan seed is needed by detoxification treatment, ice after the crude extract of banyan seed is mixed with deionized water Freeze and cause 0 DEG C, be subsequently placed in vacuum drying chamber, vacuumize extraction, detoxification Hu Rongshu seed crude extracts are obtained after extraction.
(3) banyan seed crude extract is dissolved with distilled water, then surpasses the doughnut that solution excess pressure is 0.05MPa Filter membrane, banyan seed extract is obtained by gained filtrate after the hollow fiber ultrafiltration membrane that pressure is 0.05MPa, filtrate drying;
(4) rheum officinale, Teng pears root, balsamine son, Sculellaria barbata, nidus vespae are weighed respectively by weight ratio, after crushing with banyan Seed extract mixes, that is, obtains cancer therapy drug.
Due to containing alkaloid in banyan seed, part population can be caused to produce the danger of poisoning, therefore, in the present invention The step of removing alkaloid is added, to reduce side effects of pharmaceutical drugs.
Beneficial effects of the present invention:The cancer therapy drug of the present invention is preferable for the therapeutic effect of cancer, and sufficiently profit With this plant resources of banyan, it is more preferably played a role.Simultaneously because the step of adding detoxification, the poison of medicine can be reduced Side effect.
Embodiment
The present invention is described in detail below:
Embodiment 1
A kind of cancer therapy drug, in parts by weight, including banyan seed extract 5g, rheum officinale 2g, Teng pears root 2g, balsamine Young 2g, Sculellaria barbata 2g, nidus vespae 1g.
Embodiment 2
A kind of cancer therapy drug, in parts by weight, including banyan seed extract 10g, rheum officinale 3g, Teng pears root 3g, phoenix are celestial Spend young 3g, Sculellaria barbata 3g, nidus vespae 2g.
Embodiment 3
The processing method of cancer therapy drug, comprises the following steps:
(1) banyan seed is taken, grind into powder, then sieves banyan powder of seeds, and then being flowed back with petroleum ether removes fat Soluble substance and impurity, then with 95% alcohol reflux, slough chlorophyll and alcohol-soluble small-molecule substance, banyan seed is obtained after drying Crude extract;
(2) crude extract of banyan seed is needed by detoxification treatment, ice after the crude extract of banyan seed is mixed with deionized water Freeze and cause 0 DEG C, be subsequently placed in vacuum drying chamber, vacuumize extraction, detoxification Hu Rongshu seed crude extracts are obtained after extraction.
(3) banyan seed crude extract is dissolved with distilled water, then surpasses the doughnut that solution excess pressure is 0.05MPa Filter membrane, banyan seed extract is obtained by gained filtrate after the hollow fiber ultrafiltration membrane that pressure is 0.05MPa, filtrate drying;
(4) rheum officinale, Teng pears root, balsamine son, Sculellaria barbata, nidus vespae are weighed respectively by weight ratio, after crushing with banyan Seed extract mixes, that is, obtains cancer therapy drug.
The above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although with reference to preferred embodiment to this hair It is bright to be described in detail, it will be understood by those of ordinary skill in the art that, it can modify to technical scheme Or equivalent substitution, without departing from the objective and scope of technical solution of the present invention, it should all cover the claim in the present invention Among scope.

Claims (3)

  1. A kind of 1. cancer therapy drug, it is characterised in that in parts by weight, including 5-10 parts of banyan seed extract, rheum officinale 2-3 Part, 2-3 parts of Teng pears roots, 2-3 parts of balsamine son, 2-3 parts of Sculellaria barbata, 1-2 parts of nidus vespae.
  2. 2. a kind of processing method of cancer therapy drug as claimed in claim 1, it is characterised in that comprise the following steps:
    (1) banyan seed is taken, grind into powder, then sieves banyan powder of seeds, then fat-soluble with petroleum ether reflux removing Material and impurity, then with 95% alcohol reflux, slough chlorophyll and alcohol-soluble small-molecule substance, banyan seed is obtained after drying and is slightly carried Take thing;
    (2) banyan seed crude extract is dissolved with distilled water, then the Hollow Fiber Ultrafiltration by solution excess pressure for 0.05MPa Film, banyan seed extract is obtained by gained filtrate after the hollow fiber ultrafiltration membrane that pressure is 0.05MPa, filtrate drying;
    (3) rheum officinale, Teng pears root, balsamine son, Sculellaria barbata, nidus vespae are weighed respectively by weight ratio, is carried after crushing with banyan seed Take thing to mix, that is, obtain cancer therapy drug.
  3. 3. the processing method of cancer therapy drug according to claim 2, it is characterised in that the crude extract of banyan seed need by Detoxification treatment, 0 DEG C of frost cause, is subsequently placed in vacuum drying chamber, vacuumizes after the crude extract of banyan seed is mixed with deionized water Extraction, obtains detoxification Hu Rongshu seed crude extracts after extraction.
CN201711500395.1A 2017-12-30 2017-12-30 A kind of cancer therapy drug Pending CN108030811A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711500395.1A CN108030811A (en) 2017-12-30 2017-12-30 A kind of cancer therapy drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711500395.1A CN108030811A (en) 2017-12-30 2017-12-30 A kind of cancer therapy drug

Publications (1)

Publication Number Publication Date
CN108030811A true CN108030811A (en) 2018-05-15

Family

ID=62098197

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711500395.1A Pending CN108030811A (en) 2017-12-30 2017-12-30 A kind of cancer therapy drug

Country Status (1)

Country Link
CN (1) CN108030811A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114191409A (en) * 2021-10-15 2022-03-18 张树刚 Hydrogen capsule based on health care, anticancer, antioxidation and toxin expelling

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114191409A (en) * 2021-10-15 2022-03-18 张树刚 Hydrogen capsule based on health care, anticancer, antioxidation and toxin expelling

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Application publication date: 20180515

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