KR101028073B1 - Natural herb medicine composition improving blood circulation and immune activity of human body and its process of production - Google Patents
Natural herb medicine composition improving blood circulation and immune activity of human body and its process of production Download PDFInfo
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- KR101028073B1 KR101028073B1 KR1020100119883A KR20100119883A KR101028073B1 KR 101028073 B1 KR101028073 B1 KR 101028073B1 KR 1020100119883 A KR1020100119883 A KR 1020100119883A KR 20100119883 A KR20100119883 A KR 20100119883A KR 101028073 B1 KR101028073 B1 KR 101028073B1
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- fermentation
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- sewage
- licorice
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Abstract
Description
본 발명은 혈액순환을 개선하여 인체의 면역력을 높이고 신체 각 부위의 기능을 활성화하여 줄 수 있는 생약제 조성물에 관한 것이다.
The present invention relates to a herbal composition that can improve the blood circulation to increase the body's immunity and to activate the function of each part of the body.
최근에는 기존의 합성 화합물들에 의한 질환치료제의 개발의 한계와 치료시의 부작용 및 독성에 관한 문제점들로 인해 생약제제를 중심으로 한 질환치료제의 개발이 활발히 진행되고 있다.
Recently, due to limitations of the development of disease treatments by synthetic compounds and problems related to side effects and toxicity during treatment, development of disease treatments based on herbal medicines has been actively conducted.
본 발명은 기존에 널리 이용되어오는 생약제를 배합하여 섭취시 혈액순환을 개선하여 인체의 면역력을 증강시키고, 각 신체 부위의 활성화를 촉진할 수 있는 식이성 생약제 조성물을 제공하고자 한다.
The present invention is to provide a dietary herbal composition that can enhance the body's immunity and promote the activation of each body part by improving the blood circulation when ingested by combining the conventionally used herbal medicine.
본 발명은 다양한 생약제를 검토하여 본 결과 독활, 감초, 어성초, 천궁, 계피, 삼백초, 뽕잎, 인삼, 황기, 당귀, 석창포, 후우, 봉출, 하수오, 정향을 선발하여 이들을 특정비율로 배합 섭취한 결과, 혈액순환을 개선하여 인체의 면역력과 인체장기의 활성화가 크게 높아지도록 하였다.
The present invention is a result of reviewing various herbal medicines as a result of ingestion of poisonous, licorice, eoseongcho, cheongung, cinnamon, three hundred seconds, mulberry leaves, ginseng, Astragalus, Angelica, Seokchangpo, hoo, bongsu, sewage, clove, and ingested them in a specific ratio In addition, blood circulation was improved to increase the body's immunity and vital organs.
본 발명의 조성물을 다양한 사례별로 복용한 결과는 아래와 같다.The results of taking the composition of the present invention in various cases are as follows.
도 1 은 본 발명의 생약조성물을 섭취한 케이스 1의 루프스 환자의 RBC변화측정 그래프,
도 2 는 본 발명의 생약조성물을 섭취한 루프스 환자의 OLT 변화측정 그래프,
도 3 은 본 발명의 생약조성물을 섭취한 케이스2의 만성신부전증환자의 RBC변화 측정 그래프,
도 4 는 본 발명의 생약조성물을 섭취한 케이스2의 만성신부전증환자의 PLT변화측정 그래프,
도 5 는 본 발명의 생약조성물을 섭취한 급성간염환자의 GOT, GPT 변화 측정 그래프,
도 6 은 본 발명의 생약조성물을 섭취한 당뇨,고혈압, 지방간 환자의 글루코스, GOT, GPT r-GTP 의 변화측정 그래프임.1 is a graph of RBC change measurement of Lupus patients in case 1 ingesting the herbal composition of the present invention,
Figure 2 is a graph measuring the OLT change of Lupus patients ingesting the herbal composition of the present invention,
Figure 3 is a graph of the measurement of RBC changes in patients with chronic kidney failure in case 2 ingested the herbal composition of the present invention,
Figure 4 is a graph of the measurement of PLT changes in patients with chronic kidney failure in Case 2 ingesting the herbal composition of the present invention,
5 is a graph measuring the GOT, GPT changes of acute hepatitis patients ingesting the herbal composition of the present invention,
Figure 6 is a graph measuring the change in glucose, GOT, GPT r-GTP of the diabetic, hypertension, fatty liver ingested herbal composition of the present invention.
본 발명은 운지버섯자실체추출분말, 독활, 감초, 어성초, 천궁, 계피, 삼백초, 뽕잎, 인삼, 황기, 당귀, 석창포, 후우, 봉출, 하수오, 정향을 중량을 기준으로 각각 13.3, 9,1, 8.4, 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4, 2.5%의 비율로 조합하여 인체 면역증진기능과 활성화기능을 갖는 생약조성물를 개발하였다.In accordance with the present invention, the fingerlings of the fruiting body extract powder, venom, licorice, eoseongcho, cheongung, cinnamon, three hundred vine, mulberry leaf, ginseng, Astragalus, Angelica, Seokchangpo, hoo, bongsu, sewage, clove by weight 13.3, 9, 1, Herbal compositions with human immunostimulating and activating functions were developed by combining 8.4, 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4 and 2.5%.
본 발명에서 운지버섯은 막대한 의학적 가치를 갖는 버섯으로써 중국 명나라때 Li Shi Zhen의 'Compedium of Materia medica' 에 이미 기록되어 있다. 이 버섯은 역사적으로 중국뿐만 아니라 세계 여러나라에서 건강식품으로 주의를 끌었다. 상기 버섯에서 다양한 화합물을 분리하였으며, 그들 중 어떤 것은 판매되기도 한다. 상기 버섯 유래의 다당류펩티드(polysaccharopeptide, PSP)는 면역조절, 항암, 간보호 활성을 갖고 있으며, 암환자에게 면역조절제와 항암제로 사용되어 왔다. 상기 다당류펩티드와 매우 유사한 다당류로 운지버섯에서 분리한 크레스틴(PSK, krestin)이 있으며, 혈액순환을 개선하고, 면역증강활성을 갖고 있음이 입증되어 있다. 그러나, 다른 의학적 활성들을 찾기 위한 상기 버섯종에 대한 계속적인 연구들이 시도되고 있다. 본 발명에서는 운지버섯의 자실체를 구매하고 이를 잘게 자른 다음 분쇄하고 2시간 동안 고온·고압 하에서 멸균하고 이를 여과하여 얻은 상등액을 동결건조하여 목적한 운지버섯 자실체 추출분말로 하였다.In the present invention, the fingering mushroom is a mushroom of enormous medical value, which is already recorded in the 'Compedium of Materia medica' of Li Shi Zhen in the Chinese Ming Dynasty. This mushroom has historically attracted attention as a health food not only in China, but also in many parts of the world. Various compounds were isolated from the mushrooms, some of which may be sold. The mushroom-derived polysaccharide peptide (polysaccharopeptide (PSP)) has immunomodulatory, anticancer and hepatoprotective activities and has been used as an immunomodulator and anticancer agent in cancer patients. There is a polysaccharide very similar to the polysaccharides, crestine (PSK, krestin) isolated from the fingering mushrooms, it has been proved to improve blood circulation and have immune enhancing activity. However, ongoing studies on the mushroom species to find other medical activities have been attempted. In the present invention, the fruiting body of the fingering mushrooms were purchased, chopped and pulverized, sterilized under high temperature and high pressure for 2 hours, and the supernatant obtained by filtration was lyophilized to obtain the desired fingerling fruiting body extract powder.
본 발명에서 독활 (獨活, Aralia cordata THUNB.)은 두릅나무과 (Araliaceae)에 속하는 다년생초본으로 높이는 1.2 m에 달하며 줄기 곳곳에 짧은 털이 나 있다. 잎은 3~ 5장의 잔잎으로 된 겹잎으로 어긋나며, 잔잎 가장자리에는 톱니가 있다. 꽃은 연한 초록색으로, 암꽃과 수꽃이 따로 한 그루에 피는데, 7~ 8월에 가지 끝에 산형(傘形) 꽃차례로 핀다. 열매는 장과 (漿果)로 10월에 검은색으로 익는다. 흔히 약으로 쓰기 위해 심기도 하는데, 한방에서 쓰는 독활은 봄과 가을에 뿌리줄기 및 뿌리를 캐서 겉껍질을 벗겨 햇볕에 말린 것으로 편두통 치료에 쓰인다. 뿌리를 캐자마자 바로 햇볕에 말리면 향기가 없어지므로 바람이 잘 통하는 그늘에서 어느 정도 말린 다음 햇볕에 말리는 것이 좋다. 맛은 맵고 성질은 따뜻하며 무독하며, 해열작용, 진통작용, 진경작용, 소염작용, 혈액응고 촉진작용, 강심작용, 강압작용 등의 효능이 있다. 민간에서는 전초를 해열제, 이뇨제 및 진통제로 사용한다. 약으로는 뿌리를 사용하는데 거풍제습, 통비지통의 효능이 있어 비증, 신경통, 두통, 중풍 후유증, 혈액순환개선 등의 처방에 사용한다. 뿌리에는 정유 (essential oil)가 함유되어 있고, 정유 중에는 리모넨 (limonen), 사비넨(sabnene), 알파-피넨 (α-pinene), 감마-테르피넨 (γ-terpinene), 미르센 (myrcene), 휴물렌 (humulene, α-caryophyllene), 알파-코페인 (α-copaene), 테르피넨-4-올 (terpinene-4-ol)이 함유되어 있다 (정보섭 및 신민교저, 도해향약 대사전, 영림사, p435, 1998).In the present invention, the poisonous (Aralia cordata THUNB.) Is a perennial herb belonging to the family Araliaceae, reaching 1.2 m in height and having short hairs around the stem. The leaves are alternated with the leaves of 3 to 5 leaves, with the teeth on the edges of the leaves. The flower is light green, and the female flower and the male flower bloom in one branch, and in July-August, the inflorescence blooms at the end of the branch. Fruit is berry and ripens in October in black. It is often planted for use as a medicine. In the spring, the poisonous poison is used to treat migraines in the spring and autumn by cutting off the rhizome and roots and peeling the sun. As soon as the roots are dried in the sun, the fragrance will disappear, so it is better to dry them in a well-ventilated shade and dry them in the sun. The taste is hot and the nature is warm and nontoxic, fever, analgesic, jingyeong, anti-inflammatory, blood coagulation promoting action, cardiac action, coercive action. In the private sector, outposts are used as antipyretics, diuretics and analgesics. Root is used as a medicine, and it has the effects of dehumidification and tongji pain, so it is used to prescribe nausea, neuralgia, headache, sequelae after stroke, and improve blood circulation. The root contains essential oils, and essential oils include limonen, sabnene, alpha-pinene, gamma-terpinene, myrcene, myrcene, It contains humulene (α-caryophyllene), alpha-copaene (alpha-copaene) and terpinene-4-ol. p435, 1998).
독활은 관절염의 주요 유발인자인 COX를 저해시키고, 진통, 저체온증, 근육운동 저하에 대한 치료 효과가 있다고 보고되어진다(Dang NH, et al., Inhibitory constituents against cyclooxygenases from Aralia cordata Thunb. Arch Pharm Res., 28(1), pp.28-33, 2005 Jan). Toxicity inhibits COX, a major inducer of arthritis, and has been reported to have therapeutic effects on analgesia, hypothermia, and muscle locomotion (Dang NH, et al., Inhibitory constituents against cyclooxygenases from Aralia cordata Thunb. Arch Pharm Res. , 28 (1), pp. 28-33, 2005 Jan).
어성초는 삼백초과에 속하는 다년생 초본으로서, 특이하게 비린내가 심하게 나는 약초이다. 어성초는 비린내 성분인 데 카노일 아세트알데히드(decanoil acetaldehyde) 및 플라보노이드를 함유하고 있어 각각 항염작용 및 혈액정화 작용, 혈액순환을 나타내며, 본초강목에서는 어성초가 해열, 종기, 탈항, 독을 없애고 중금속을 해독한다고 기록하고 있다.Eoseongcho is a perennial herb belonging to more than three hundred, unusually fishy herb. Eochocho contains fishy decanoil acetaldehyde and flavonoids, which are anti-inflammatory, blood purification, and blood circulation, respectively. It is recorded.
감초는 콩과의 다년생 초본으로, 약 중의 원로라는 의미인 국로로 불리기도 한다. 따라서, 감초는 다른 약들과 함께 사용되어 약의 효과를 잘 조화되게 하고 독을 중화시켜 주는 작용을 한다. 그밖에도 동의보감에서는 오장육부의 병을 다스리고 눈, 코, 입, 귀와 대소변의 생리를 조절하며 인체의 혈맥을 잘 소통시키고, 근육과 뼈를 튼튼하게 해준다고 기록되어 있다.Licorice is a perennial herb of legumes, also known as Gukro, meaning elder in medicine. Thus, licorice is used in combination with other drugs to harmonize the drug's effects and neutralize the poison. In addition, it is recorded that Dongbogam controls the disease of the five intestines, controls the physiology of eyes, nose, mouth, ears and faeces, communicates the blood vessels of the human body, and strengthens muscles and bones.
천궁은 산형화목 산형과의 여러해살이풀로서 높이는 30∼60㎝까지 자라며 뿌리줄기는 굵고 전체에 털이 없으며 진정·진통 및 강장제로 쓴다. Cheongung is a perennial herb of mountainous hawthorn and grows up to 30 ~ 60㎝. The root stem is thick and hairless, and it is used as calming, analgesic and tonic.
천궁 전초에는 쿠마린, 만니톨이 있고, 뿌리에는 정유성분인 크니딜리디, 네오크티딜리드, 리쿠스틸리드, 천궁산, 부틸푸탈리드, 천궁산에스테르 등이 1~2% 정도 함유되어 있다. 천궁의 크니딜리드 등은 천궁의 고유한 냄새 성분으로 점막충혈작용이 있다. 이러한 정유는 실험동물의 뇌를 약하게 마비시키고 혈압을 낮추고 운동마비 등을 일으키는 물질이지만, 중추신경장애를 정상으로 회복시키며, 사람에게는 진통, 진정 작용과 혈압을 내리고 말초혈관을 확장시키는 것으로 알려져 있다. The cheongung outpost contains coumarin and mannitol, and the root contains 1 ~ 2% of essential oils such as knidylide, neoctilide, liqueuside, cheongongsan, butylphthalide, and cheongongsan ester. Cnidylide of the uterus is a unique odor component of the hormonal mucosa has an action. Although these essential oils weaken the brains of experimental animals, lower blood pressure, and cause paralysis, they are known to restore central nervous system disorders to normal, reducing pain, sedation and blood pressure, and expanding peripheral blood vessels in humans.
계피나무(Cinnamomum cassia PRESL)는 녹나무과에 속하며, 원산지는 중국이고, 스리랑카, 인도차이나 및 한국(제주)에 분포한다. 높이 7 m, 지름 1.3 m 정도로 곧게 자라고 굵은 가지가 많이 갈라지며 잔가지가 있다. 잎은 마주나고 달걀 모양으로 넓으며 잎의 길이는 4 내지 8 cm이며, 나비는 3 내지 7 cm 정도로 끝이 다소둔하다. 앞면은 녹색, 뒷면은 분백색이고 5 내지 7개의 손바닥 모양의 맥이 있으며 가장자리에는 둔한 톱니가 있다. 계피나무의 꽃은 6월에 피고 연한 노란빛을 띤 녹색이며 새가지 끝 잎겨드랑이에 산형꽃차례로 달린다. 꽃받침은 통 모양이며 윗부분이 6개로 갈라진다. 수술은 3개씩 4줄로 늘어서고 가장 안쪽 줄은 꽃밥이 없다. 암술은 1개이고 열매는 3 내지 5개씩 달리고, 씨는 편평하며 한쪽에 날개가 있다. 주요성분으로는 19-아세틸신카시올 A, 안하이드로신젤알라닌, 카시오사이드, 유게놀, 신남알데하이드 및 시남에틸아세테이트가 있으며, 해열 작용, 진통 작용, 건위 작용, 항균 작용, 항바이러스 작용 등에 효과가 있음이 알려져 있다(www.tradimed.co.kr; 지형준 등, 한약(생약)규격집 주해서, 87p, 1998). Cinnamomum cassia PRESL belongs to the camphor tree. It is native to China and is distributed in Sri Lanka, Indochina and Korea (Jeju). It grows straight up to 7 m in height and 1.3 m in diameter. There are many thick branches and twigs. The leaves are opposite each other, broad in the shape of eggs, the leaves are 4 to 8 cm in length, and the butterflies are slightly dull at the ends of 3 to 7 cm. The front is green, the back is white, and there are 5 to 7 palm-shaped veins with dull teeth on the edges. The cinnamon tree blossoms in June, light yellowish green, and hangs in the form of inflorescence on the axillary end of the new branch. Calyx is tubular and its upper part is divided into 6 pieces. The stamens are arranged in four rows of three, and the innermost row has no anther. Pistil is one, the fruit is running three to five, seeds are flat, with wings on one side. Its main ingredients include 19-acetylcincasiol A, anhydroscingelalanine, casioside, eugenol, cinnamic aldehyde and cinnamic ethyl acetate, and it is effective in antipyretic, analgesic, dry stomach, antibacterial and antiviral effects. (Www.tradimed.co.kr; Jik-Joon et al., Medicinal Herbal Medicines Reference Manual, 87p, 1998).
계피나무 추출물, 이의 분획물 및 상기 분획물로부터 분리한 트랜스-신남알데하이드가 생체 내외 실험에서 파킨슨병 양상을 유발할 수 있는 대표적인 신경독성물질인 6-하이드록시도파민(6-hydroxydopamine; 6-OHDA)에 의한 도파민 신경세포의 손상을 보호하고, 지질다당류인 LPS(lipopolysaccharide)에 의한 신경세포의 활성을 억제할 수 있음을 확인함으로써, 본 발명의 계피나무 추출물, 이의 분획물 및 상기 분획물로부터 분리한 트랜스-신남알데하이드를 파킨슨병 예방 및 치료용 조성물의 유효성분으로 사용될 수 있음을 발견하였다.Cinnamon Extract, Fractions thereof, and Trans-cinnaaldehyde Isolated from the Fractions Dopamine by 6-hydroxydopamine (6-hydroxydopamine; 6-OHDA) By protecting the nerve cells and confirming that it is possible to inhibit the activity of the nerve cells by lipopolysaccharide (LPS) lipopolysaccharide, the cinnamon extract of the present invention, its fractions and trans-cinnamaldehyde isolated from the fractions It has been found that it can be used as an active ingredient in a composition for preventing and treating Parkinson's disease.
삼백초(Saururus chinensis BAILL.)는 삼백초과(Saururaceae)에 속하는 다년생초본으로서, 울릉도와 제주도 서북 지역의 물가나 습지에서 서식하며, 국외로는 일본, 중국, 필리핀에 분포한다. 높이는 60 내지 90cm로 근경은 흰색으로 진흙 속에서 옆으로 뻗어나가며 꽃이 필 때 윗 부분의 2-3개의 잎, 꽃 및 뿌리가 희기 때문에 삼백초라고 한다(고 경식, 전 의식, 한국의 야생식물, 일진사, p91, 2003). 전초에는 정유가 함유되어 있으며, 그 주성분은 퀘르세틴(quercetin),퀘르시트린(quercitrin), 이소퀘르시트린(isoquercitrin), 루틴(rutin) 및 수용성 탄닌(tannin) 등이며, 해독, 소종, 소변불리, 간염, 황달 등의 치료에 이용된다(김 재길, 천연물대사전, 남산당, p174, 1984). 삼백초의 주성분인 퀘르세틴 및 퀘르시트린은 플라보노이드(flavonoid)의 일종으로 플라보놀(flavonol)계통에 속하며, 과일이나 채소류에 많이 들어있는 성분이다(Formica J. et al., Food and Chemical Toxicology, 33, pp1061-1080, 1995). 퀘르세틴의 약리작용으로는 과산화지질 형성 억제작용(Cavallin L. et al., Pharmacol. Res. Commun., 10, pp133-136, 1978), 항바이러스(Veckenstedt A. et al., Arch. Virol ., 57, pp255-260, 1978), 항균 효과(Kimura M. et al., Yakugaku Zasshi., 104, pp340-346,1984), 항돌연변이 작용(Edenhader R. et al., Agricultural Chemistry and Biotechnology, 39, pp357-372, 1996) 및 발암성 물질의 활성감소, 변이 암세포의 생육저해, 혈압 강하, 모세혈관 강화 작용, 혈액순환개선 등이 알려져 있으며, 퀘르시트린은 항염증 및 진통 효과(Park et al., J. Korean Soc. Food Sci. Nutr., 23, pp671-674, 1994), 항산화 효과(Mun S. et al., J.Korean Soc. Food Sci. Nutr., 23, pp466-471, 1994)가 있다고 알려져 있다. The three hundred herb (Saururus chinensis BAILL.) Is a perennial herb belonging to the Saururaceae, and is found in waterside and wetlands in Ulleungdo and northwestern Jeju Island, and is distributed in Japan, China, and the Philippines. It is 60-90cm in height and root length is white and stretches sideways in the mud. It is called three hundred seconds because 2-3 leaves, flowers and roots are white when the flowers bloom (Go Kyung, Je Ri, Korean wild plants, Iljinsa, p91, 2003). Outpost contains essential oils, the main ingredients of which are quercetin, quercitrin, isoquercitrin, rutin and water-soluble tannins, detoxification, swelling, urinary deficiency, hepatitis , Jaundice, etc. (Kim Jae-gil, natural product metabolism, Namsandang, p174, 1984). Quercetin and quercitrin, the main components of the three hundred sec, are flavonoids and belong to the flavonol family and are found in many fruits and vegetables (Formica J. et al., Food and Chemical Toxicology, 33, pp1061). -1080, 1995). The pharmacological action of quercetin is to inhibit lipid peroxidation (Cavallin L. et al., Pharmacol. Res. Commun., 10, pp 133-136, 1978), antivirus (Veckenstedt A. et al., Arch. Virol., 57, pp255-260, 1978), antimicrobial effect (Kimura M. et al., Yakugaku Zasshi., 104, pp340-346,1984), antimutagenic activity (Edenhader R. et al., Agricultural Chemistry and Biotechnology, 39, pp357-372, 1996) and reduced activity of carcinogenic substances, reduced growth of mutant cancer cells, lowering blood pressure, capillary potentiation, and improving blood circulation. Quercitrin has anti-inflammatory and analgesic effects (Park et al., J. Korean Soc.Food Sci.Nutr., 23, pp671-674, 1994), and antioxidant effects (Mun S. et al., J. Korean Soc.Food Sci.Nutr., 23, pp466-471, 1994) It is known.
뽕잎 속에는 아미노산이 24가지나 들어있다. 우리 몸은 단백질로 구성되어 있고 단백질은 바로 아미노산이 모여서 만들어진 것이다. 집으로 말하자면 단백질은 집의 벽이고 아미노산은 이 벽을 이루고 있는 벽돌이라고 할 수 있다. There are 24 amino acids in the mulberry leaves. Your body is made up of proteins, and proteins are made up of amino acids. In the house, protein is the wall of the house and amino acids are the bricks that make up the wall.
뽕잎 속에 들어있는 아미노산을 분석해보면 술을 분해시켜주는 ‘알라닌’과 ‘아스파라긴산’ 성분이 풍부하고, 뇌 속의 피를 잘 돌게 하고, 혈액순환을 원활히 하고, 콜레스테롤 제거 및 노인성 치매를 예방해주는 ‘세린’과 ‘타이론신’ 성분이 각각 1.2%. 0.8% 들어있다. Analyzing the amino acids in the mulberry leaves is rich in alanine and aspartic acid, which breaks down alcohol, helps blood flow in the brain, facilitates blood circulation, removes cholesterol, and prevents dementia. And 'tyrone' are 1.2% respectively. Contains 0.8%
뽕잎에는 칼슘과 철분을 비롯한 50 여 종 이상의 미네랄이 풍부하게 들어있다. Mulberry leaves are rich in more than 50 minerals, including calcium and iron.
우리가 즐겨 마시는 녹차와 비교해 보면 칼슘은 6.1배, 철분은 2.2배, 칼륨은 1.4배, 섬유성분은 4.7배나 높다. 특히 칼슘이 풍부해 대표적 칼슘 식품인 우유의 6배이고, 철분은 시금치의 3배나 더 많이 들어있다. Compared to our favorite green tea, calcium is 6.1 times, iron is 2.2 times, potassium is 1.4 times, and fiber is 4.7 times higher. In particular, it is rich in calcium, six times the typical calcium food milk, and three times more iron than spinach.
식이섬유가 풍부하게 함유되어 있어서 변비 완화 및 다이어트에도 효과가 높다. Rich in dietary fiber is also effective in reducing constipation and diet.
뽕잎에는 당뇨에 효과가 있는 모란 A라는 성분과 알파 글루코시데이즈 제해제라고 알려진 노지리마이신과 칼리스테진 등이 함유되어 있다. 뽕잎의 높은 섬유 성분은 중금속을 몸 밖으로 내보내는 역할을 한다. 환경공해의 심각성이 더욱 부각되는 요즘, 오염된 공기나 식품 등으로 인한 중금속이 인체에 쌓이는 것에 대한 공포감을 갖고 있다. 중금속은 우리 몸속에 들어와 밖으로 나가지 않고 뇌 속이나 신경조직으로 들어가면 몸이 이유 없이 아프던지, 판단력을 떨어뜨리며, 각종 질병을 초래하는 원인이 된다. 뿐만아니라 양약을 상시 복용하는 사람들에게 뽕잎차는 간의 해독제로서 탁월한 효과가 있다. 뽕잎은 우리 몸에 해로운 카드뮴이나 구리, 아연 등과 같은 중금속을 몸 밖으로 배출시키는 효과가 있다. The mulberry leaves contain a component called peony A, which is effective for diabetes, and nozirimycin and calistin, known as alpha glucosidase inhibitors. The high fiber content of the mulberry leaves the heavy metals out of the body. Nowadays, the severity of environmental pollution is highlighted, and there is a fear of heavy metals accumulated in the human body due to polluted air or food. Heavy metals enter the body and go out into the brain or nerve tissue without going out, the body hurts for no reason, or lose judgment, causing a variety of diseases. In addition, mulberry leaf tea has an excellent effect as an antidote for liver to those who take regular doses. Mulberry leaves are effective in discharging heavy metals such as cadmium, copper, and zinc that are harmful to our bodies.
장미목 콩과의 여러해살이풀인 황기는 높이 1m 정도이며, 한방에서는 황기뿌리를 완화(緩和)·강장(强壯)·지한제(止汗劑)로 쓴다. 한국·중국 등 산지에서 자란다. 약용으로 이용되는 뿌리의 크기는 재배지역에 따라 차이가 있는데 길이는 20∼100cm, 지름은 0.5∼1.5cm로 다양하다. 황기는 땀구멍을 조절하고 기를 돋워주어 지나치게 땀이 많이 흐르는 것을 막아주는데, 황기를 그대로 달여 마시거나 닭과 함께 황기 백숙을 만들어 먹는다. 차로 마실 때는 물에 오래 달인 다음에 체로 걸러 황기는 버리고 달인 물에 꿀을 섞어 차게 보관했다가 마신다. 또한 황기는 이뇨작용, 강심작용, 강장보혈 작용이 있으며, 혈관을 확장시켜 혈액순환을 좋게 하는 것으로 알려져 있다. 약용으로 이용되는 뿌리에는 포모노네틴(Formononetin), 베타인(Betain), 콜린(Cholin), 이소리퀴리티게닌(Isoliquiritigenin) 쿠마린(coumarin), 엽산(folic acid) 등 성분이 함유되어 있다. 아미노산(aminoacid)으로는 혈압강하작용이 있는 GABA(γ-Aminobutyric acid)와 누에의 변태저지작용이 있는 L-canavanine 성분이 함유되어 있다. 그리고 항균작용이 있는 이소플라보노이드 성분과 강장작용이 뛰어난 사포닌(astragaloside) 성분이 들어 있다.The perennial herb, a perennial herb, is about 1 m high, and in oriental medicine, the root is used as a relief, tonic, and antiperspirant. It grows in mountains such as Korea and China. The size of the roots used for medicinal purposes varies depending on the cultivation area. The length varies from 20 to 100 cm and the diameter is 0.5 to 1.5 cm. Astragalus is to control the pores and boost the energy to prevent excessive sweating, Astragalus intact or drink with the chicken to make Astragalus. When you drink tea, boil it in water for a long time, sift it, discard it, and mix it with decoction water to keep it cool. In addition, Astragalus has a diuretic effect, cardiac effect, tonic blood, and is known to improve blood circulation by expanding blood vessels. Roots used for medicinal purposes include Formononetin, betaine, Choline, Isoliquiritigenin, coumarin, and folic acid. Amino acids include GABA (γ-Aminobutyric acid), which has a blood pressure-lowering effect, and L-canavanine, which has a metastatic inhibition of silkworms. It also contains antibacterial isoflavonoids and tonic saponin (astragaloside).
당귀는 보혈의 효능이 있으므로 얼굴에 핏기가 없고 현기증이 자주 나며 눈과 입술에 윤기가 없는 사람에게 효능이 있다고 알려져 있다. 몸이 허약하여 오는 두통, 여성들의 월경 조절 효능이 뛰어나므로 산전이나 산후의 여러 질병에 자주 사용되며, 월경불순, 복통을 치료한다. 위장의 기능이 약해서 오는 변비 치료에 효과가 있다(배 기환 저, 민간요법과 한방요법에 따른 건강지침서 원색도감, pp102-103, 2003). 당귀에는 데커신(Decursin), 데커시놀(Decursinol), 노다케네틴(Nodakenetin) 등의 쿠마린 (Coumarin) 유도체와 α-피넨(Pinene), 리모넨(Limonene), β-유데스몰(Eudesmol), 에레몰(Elemol) 등의 정유 성분을 약 0.2% 함유하고 있고 이외에도 리구스틸리드(ligustilide), 부틸리덴프탈리드(butylidene phthalide), 크니딜리드(cnidilide), 이소크니딜리드 (isocnidilide), 세스퀴테르펜류(sesquiterpene), p-시멘(cymene), 시토스테롤(sitosterol)등의 성분이 함유된 것으로 알려져 있으며, 자궁기능 조절작용, 진정작용, 진통작용, 항균작용, 설사작용 및 비타민 E 결핍치료작용을 하므로 빈혈증, 진통, 강장, 통경 및 부인병약으로 쓰이며 봄에 어린순을 나물로 식용하기도 한다(정보섭, 신민교저, 영림사, 향약대사전 p407-408, 1998년).Angelica is known for its efficacy in blood, so it is said to be effective for people who do not have a pimple on the face, have dizziness frequently and have no gloss on eyes and lips. Headache is weak body, women's menstrual control effect is excellent, so it is often used in various prenatal and postpartum diseases, and it treats menstrual irregularities and abdominal pain. It is effective in treating constipation due to weak gastrointestinal function (Bae Ki-hwan), color guidebook for health guidelines according to folk remedies and herbal remedies, pp102-103, 2003. Cogmarin derivatives such as Decursin, Decursinol and Nodakenetin, α-Pinene, Limonene, β-Eudesmol, It contains about 0.2% of essential oils such as olemol, and in addition to ligustilide, butylidene phthalide, chnidilide, isocidilide and ses It is known to contain ingredients such as squiterpene, ps-cymene, and sitosterol, and it controls uterine function, sedation, analgesic, antibacterial action, diarrhea and vitamin E deficiency treatment. Since it is used for anemia, analgesic, tonic, pain and gynecological medicine, young sprouts are edible in spring (Information, Shin Mingyo, Yeonglimsa, Hyangjeomsa p407-408, 1998).
석창포는 천남성과(Araceae)에 속하는 다년생 초본인 아코루스 그라미네우스 솔란드(Acorus gramineus Soland) 및 동속 근연식물의 뿌리를 건조한 것으로서, 개규활담(開竅豁痰), 성신익지(醒神益智), 화습개위(化濕開胃)의 효능을 가진다고 알려져 있다. 구체적으로 석창포는 간장, 비장, 심장에 작용하는데 진정, 건위, 진통, 이뇨, 항진균의 약리 작용을 가지며, 임상에서는 발열, 의식몽롱상태, 의식장해, 번조, 불안, 호흡촉박, 안면홍조, 안충혈, 두훈, 난청등의 열성질환에 사용되고 있고, 신선품이 고열의 의식장해에 대해 강한 효력을 나타낸다고 알려져 있다. 또한, 평활근 해경작용이 있어 내복시 소화액분비를 촉진하며 위장의 이상발효를 억제하고 장관평활근을 이완시키는 작용을 한다. Seokchangpo is a dried root of perennial herb, Acorus gramineus Soland and related plants, which belong to Araceae. It is known to have the efficacy of huahwa dog. Specifically, Seokchangpo acts on the liver, spleen, and heart, and has pharmacological effects of calming, stomachache, analgesia, diuresis and antifungal.In clinical practice, fever, consciousness, consciousness, distress, anxiety, respiratory discomfort, hot flashes, and nystagmus It is used for febrile illnesses such as Duhun, deafness, and is known that fresh product has strong effect against consciousness disorder of high fever. In addition, there is a smooth muscle haeparoscope function to promote the secretion of digestive juice during oral administration, inhibits abnormal fermentation of the stomach and relaxes the intestinal smooth muscle.
봉출(蓬朮)(Zedoariae Rhizoma)의 원 산 지는 히말라야 동부와 인도 동북부 인도 벵골 지방에서는 카쿠라(Kakura) 라고 한다. 대만, 일본, 중국남부지방 분포하여 임지(林地)부근의 양지쪽에서 자라며 가을과 겨울에 채취를 한다. 다년생 숙근초본으로 높이는 약 1m, 근경은 둥근 괴상으로 측면에 원주형의 가지를 내며, 측근은 둥근 괴근으로 성장하는 데 가로로 자른면은 중심이 옅은 남색을 띠며 서서히 흑변한다. 잎은 서로 감싸면서 줄기처럼 된다. 어긋나고 엽병이 길며, 폭은 20㎝정도, 엽맥의 중앙에는 1본(本)의 자색 조문이 있고, 꽃줄기가 잎보다 먼저 자라며 길이 6 ~ 15 cm로 되고 잎이 없으며 잎집으로 싸이고 끝에 수상꽃차례[穗狀花序] 로 달린다. 꽃은 수상화서로 뿌리에서 나오며 3∼5월에 피며 꽃이삭은 자홍색 포(苞)로 싸여있어 아름답다. 과실은 삭과로 둥근 삼각형이고 종자는 긴 원형이다. The origin of the Zedoariae Rhizoma is called Kakura in the eastern Himalayas and the Bengal province of northeastern India. It is distributed in Taiwan, Japan, and southern China, grows on both sides of forest land, and is harvested in autumn and winter. It is a perennial root herb, about 1m in height, rhizome with round masses, with cylindrical branches on the side, and the apex grows into round muscles. The horizontal cut side is light indigo blue and gradually turns black. The leaves wrap together and become like stems. It is alternately long and has long leaves, about 20cm wide, with one purple palate at the center of leaf vein, the stalk grows earlier than the leaves, and it is 6-15cm long, without leaves, wrapped with leaflets, at the end of water inflorescence [穗 狀 花序] run. Flowers are watery inflorescences that come from the roots and bloom in March-May. The flowers are beautifully wrapped in fuchsia. Fruits are triangular, round, and seeds are long circles.
모든 기를 잘 돌게 하고 월경을 잘하게 하며 어혈을 풀리게 하고 명치 아래와 복통을 멎게 한다. 현벽을 삭이고 분돈(奔豚)을 낫게 한다. Turn all the phases well, menstruation is good, bleeding to loosen up the abdomen and stop abdominal pain. Break the walls and heal the eggs.
이 약은 아주 딴딴하고 굳기[堅硬] 때문에 부스러뜨리기 어려우므로 뜨거운 잿불 속에 묻어 잘 구워서 뜨거울 때 절구에 넣고 짓찧으면 부서져서 가루가 된다[본초]. This medicine is very hard and hard to break because of hardening, so it is buried in hot ashes and baked well. When it is hot, put it in mortar and crush it to become powder.
하수오는 마디풀목 마디풀과의 여러해살이풀로, 길이는 약 1∼3 m 이다. 줄기가 땅바닥으로 길게 뻗거나 다른 것을 감아 오르는 덩굴성 식물이다. 뿌리는 옆으로 길게 뻗으며, 군데군데에 고구마와 같은 굵은 덩이뿌리가 생긴다. 원줄기는 가지가 갈라지면서 길게 뻗어간다. 잎은 어긋나며 자라는데, 길이는 약 3∼6 ㎝이고, 나비는 약 2. 5∼4. 5 ㎝이다. 잎의 모양은 달걀모양 심장꼴이며, 가장자리는 밋밋하고 끝은 뾰족하다. 잎자루의 아랫부분에는 짧은 잎집이 있다. 꽃은 8∼9월에 원추꽃차례로 핀다. 원추꽃차례는 긴 꽃대에 여러 개의 꽃이 어긋나게 붙으면서 밑에서부터 피기 시작하여 끝까지 피는 것으로, 전체가 원뿔모양이 되는 것을 말한다. 꽃의 빛깔은 흰색이다. 꽃받침은 5장이고 꽃잎은 없다. 수술은 8개로 꽃받침보다 길이가 짧다. 씨방은 달걀모양이고 암술대는 3개이다. 열매는 넓은 달걀모양의 수과이다. '수과'는 껍질이 얇아서 씨와 껍질이 하나로 딱 붙어있어 전체가 한 개의 열매로 보이는 것을 말한다. 열매의 크기는 2.5 ㎝정도이고, 윤기가 나며, 꽃받침으로 싸여있다. 열매는 익으면 터져서 흰 솜털이 달린 씨가 나온다. 한방에서는 붉은색을 띤 갈색 덩이뿌리를 하수오라고 하며, 강장제·강정제 및 완화제로 쓰고, 감기·신경쇠약·관절염을 치료하는데도 쓴다. . 하수오와 비슷한 것으로 나도하수오가 있는 데, 이것은 잎이 크고 열매가 날개없이 세모난 달걀모양을 하고 있고 꽃덮이에 싸여 있어서 하수오와는 다르다. 하수오는 한국을 비롯하여 중국·일본 등지에 널리 분포한다. 하수오는 크게 적하수오(Polygonum multiflorum Thunberg)와 백하수오(Cynan chum wilfordii Hemsley)의 두 가지로 구분되는데 우리나라에서 주로 재배되는 하수오는 백하수오이다. 한방에서 하수오는 간과 신장을 재생시키고, 혈액을 재보충하여 검은 머리를 나게 하는 약효를 가진 것으로 알려져 왔고, 최근에는 하수오의 혈중 콜레스테롤 농도 저하 효과가 입증되었다. 하수오의 생리적 활성은 하수오 중에 함유된 안트라퀴논에 의한 것으로 알려졌으나, 하수오에는 그 외에도 식물성 스테롤, 각종 배당체화합물을 함유하고 있다. Sewage is a perennial plant with the stalk of stalk, about 1-3m long. A vine plant whose stem extends to the ground or winds up something else. Roots stretched to the side, and thick spots like sweet potatoes are formed in several places. The main stem extends long as the branch splits. Leaves grow alternately, about 3-6 cm long, with butterflies about 2.5-5. 5 cm. The leaves are shaped like an egg-shaped heart, with flat edges and pointed ends. The lower part of petiole has short petiole. Flowers bloom in cones from August to September. Cone inflorescence starts from the bottom and blooms to the end, with several flowers attached to the long flower band alternately, and the whole becomes conical shape. The color of the flower is white. Calyx is 5 sheets and has no petals. Stamens are 8 shorter than calyx. The ovary is egg-shaped and 3 styles. The fruit is a broad egg-shaped achene. 'Fructose' is a thin skin, so the seeds and skin are stuck together in one, and the whole is seen as a single fruit. Fruits are about 2.5 cm in size, glossy, and covered with calyx. When the fruit ripens, it bursts, yielding a white downy seed. In oriental medicine, reddish brown tubers are called sewage. They are used as tonics, tonics and laxatives, and to treat colds, nervous breakdowns and arthritis. . Similar to Shouao, there is Nado Shouo, which differs from Shouo because it is large in leaf, fruit-shaped, triangular egg-shaped and wrapped in flower cover. Sewage is widely distributed in Korea, China and Japan. Sewage is divided into two types: Polygonum multiflorum Thunberg and Cynan chum wilfordii Hemsley. Sewage is cultivated mainly in Korea. Sewage in Korean medicine has been known to have the effect of regenerating liver and kidneys, replenishing blood to give black hair, and recently, sewage has been shown to reduce blood cholesterol levels. The physiological activity of sewage is known to be due to the anthraquinone contained in sewage, but sewage contains vegetable sterols and various glycoside compounds.
정향(丁香, Caryophylli Flos)은 정향과(Myrtaceae)의 정향나무(EugeniaClove (Caryophylli Flos) is an Eugenia of the Myrtaceae.
caryophyllata T.) 꽃봉오리다. 정향나무는 높이 12-20m에 달하는 상록교목으로, 잎은 난형이고 마주 난다. 몰루카 원산이며 동남아열대지방에서 재배한다. 식목한지 6년이면 흰꽃이 피고 16-20년 만에 최다의 꽃봉오리 수확을 할 수 있다. 다 핀 꽃을 말린 것을 모정향이라 하며, 꽃이 피기 전의 꽃봉오리를 수집하여 말린 것을 정향 또는 정자(丁字)라고 한다. 꽃봉오리에 정유 16-19%가 있으며, 주성분은 유게놀(euggenol), 아세틸유게놀(acetyl euggenol), α- 및 β-카리오필렌(Caryophyllene)이다. 그밖에 탄닌, 올레놀산이 들어 있다. 정향은 온리약(溫裏藥)으로 인체의 중심이 되는 비위(脾胃)와 신(腎)의 양기(陽氣)를 보(補)해 주는 약으로 노화방지의 작용이 있을 것으로 기대된다.caryophyllata T.) Bud. Clove trees are evergreen trees reaching 12-20m in height. Leaves are egg-shaped and face each other. It is native to Moluka and is grown in the Southeast Asian tropics. In six years of planting, white flowers bloom and the maximum number of buds can be harvested in 16-20 years. Dried flowers are called clove, and dried flowers are collected by collecting buds before they are called clove or sperm (丁字). There are 16-19% of essential oils in the bud, and the main components are eugenol, acetyl euggenol, α- and β-caryophyllene. It also contains tannins and olenolic acid. Clove is the only medicine, which acts as the center of the human body and protects the stomach and kidneys. It is expected to have anti-aging effects.
본 발명에서 인삼은 기존에 그 효능과 성분은 많은 연구가 되어 있어 자세한 설명은 생략하였다.In the present invention, the ginseng has been studied a lot of efficacy and ingredients in the past have not been described in detail.
상기한 조성비에 기초하여 제조하는 공정은 다음과 같다.The process of manufacturing based on said composition ratio is as follows.
운지버섯자실체 발효 추출분말, 독활, 감초, 어성초, 천궁, 계피, 삼백초, 뽕잎, 인삼, 황기, 당귀, 석창포, 후우, 봉출, 하수오, 정향을 전체중량을 기준으로 각각 13.3, 9,1, 8.4, 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4, 2.5%의 비율로 칭량하여 믹서기에서 20분간 혼합처리하는 공정,Fermented extract powder of Toji mushroom fruit, poisonous licorice, licorice, eoseongcho, cheongung, cinnamon, three hundred vinegar, mulberry leaf, ginseng, Astragalus, Angelica, Seokchangpo, hoo, bongsu, sewage, clove based on the total weight of 13.3, 9,1, 8.4 Mixing in a blender for 20 minutes, weighing at a ratio of 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4, 2.5%,
균질혼합한 것을 연합기상에서 연합하는 공정,Process of uniting homogeneous mixture on coalescence unit,
연합된 원료를 제환하는 공정,Reprocessing associated raw materials,
제환된 것을 70±2℃의 온도에서 수분함량 10중량%이하로 건조하는 공정,Process of drying the reclaimed to a moisture content of 10% by weight or less at a temperature of 70 ± 2 ℃,
충진포장하는 공정으로 이루어진다.It consists of filling and packing process.
상기한 공정에서 운지버섯 자실체 추출분말은 분말형태의 운지버섯(Coriolus versicolor) 자실체를 무기질과 유기영양소를 첨가하여 발효 한 것이다. 발효공정은 버섯 자실체 분말에 1 내지 5 중량%의 효모추출물, 펩톤 및 포도당을 첨가하여 제조된 액상 발효용 조성물에서 발효시켜 준다. In the above process, the fingering extract of the fruiting body of the fingerlings is fermented by adding inorganic and organic nutrients to the powdered fingerlings of the Coriolus versicolor. The fermentation process is fermented in a liquid fermentation composition prepared by adding 1 to 5% by weight of yeast extract, peptone and glucose to mushroom fruit body powder.
상기 발효 혼합물은 버섯 자실체 분말에 3 내지 30 중량%의 톱밥, 미강(rice bran) 및 포도당을 첨가하여 준다. 톱밥은 3 % 보다 적을 경우 충분한 생장이 어려우며, 30% 보다 많게 되면 타 영양물질이 적어지게 되어 생장이 느려져 발효에 장시간이 소요되어진다.The fermentation mixture is added to the mushroom fruit body powder of 3 to 30% by weight of sawdust, rice bran and glucose. When sawdust is less than 3%, it is difficult to grow enough, and when it is more than 30%, other nutrients are reduced, which causes slow growth and takes a long time to ferment.
이러한 발효 혼합물은 정치상태에서 배양하기도 하지만, 보다 발효를 촉진하기 위하여 진탕하면서 발효도 가능하다. 발효는 20 내지 37℃에서 1 내지 15일간 시행한다. 발효온도는 20도이하일 경우 발효자체가 중단되어지며 37도보다 높게 되면 이상발효가 이루어진다. Such a fermentation mixture may be cultured in a stationary state, but fermentation may also be performed while shaking to promote fermentation. Fermentation is carried out at 20 to 37 ° C. for 1 to 15 days. If the fermentation temperature is less than 20 degrees, the fermentation itself is stopped. If the fermentation temperature is higher than 37 degrees, abnormal fermentation takes place.
상기 버섯의 발효는 액상으로 배양하여 발효시킬 수도 있고, 고형으로 배양하여 발효시킬 수도 있다. 상기 액상으로 발효시킬 때는 버섯 자실체 분말에 1 내지 5 중량%의 효모추출물, 펩톤 및 포도당을 첨가하여 제조된 발효 혼합물(액상 발효용혼합물)을 이용하는 것이 바람직하고, 고형으로 발효시킬 때는 버섯 자실체 분말에 3 내지 30 중량%의 톱밥, 미강 및 포도당을 첨가하여 제조된 발효 혼합물(고형 발효용 조성물)을 이용하는 것이 바람직하다. 나아가, 상기 발효 혼합물에 황산마그네슘(magnesium sulfate), 인산 제 1 칼륨(potassium phosphate, monobasic; KH 2 PO4), 염화칼슘(calcium chloride), 황산아연(zinc sulfate), 황산구리(cupric sulfate), 염화망간(manganese chloride), 황산철(ferrous sulfate and ferric sulfate) 등의 무기질이 첨가될 수도 있다. 또한, 상기 발효혼합물의 배양은 정치배양, 진탕배양 또는 발효조내 배양 방법을 사용할 수 있다. 이 때 배양온도는 20 내지 37℃가 바람직하나, 보다 바람직하게는 25℃가 바람직하며, 배양기간은 1 내지 15일이 바람직하나, 보다 바람직하게는 5일이 바람직하다.Fermentation of the mushroom may be fermented by culturing in a liquid state, or may be fermented by culturing in a solid state. When the liquid fermentation in the liquid phase, it is preferable to use a fermentation mixture (liquid fermentation mixture) prepared by adding 1 to 5% by weight of yeast extract, peptone and glucose to the mushroom fruiting body powder, and when fermenting it to solid, It is preferable to use a fermentation mixture (composition for solid fermentation) prepared by adding 3 to 30% by weight of sawdust, rice bran and glucose. Furthermore, magnesium sulfate, potassium phosphate, monobasic (KH 2 PO4), calcium chloride, zinc sulfate, cupric sulfate, and manganese chloride are added to the fermentation mixture. Minerals such as manganese chloride and ferrous sulfate and ferric sulfate may be added. In addition, the culture of the fermentation mixture may be used in the culture culture, shaking culture or fermentation tank culture method. At this time, the incubation temperature is preferably 20 to 37 ° C, more preferably 25 ° C, and the culture period is preferably 1 to 15 days, more preferably 5 days.
그리고 나서, 상기 배양이 완료된 버섯 발효물로부터 열수추출 또는 열수추출 및 에탄올 처리에 의하여 추출한다. 보다 바람직하게는 상기 배양이 완료된 버섯 발효물을 90 내지 130℃로 20분 내지 2시간동안 1 내지 7회 열수추출하여 추출액을 얻은 후, 1 내지 3배량의 에탄올을 처리하여 제조한다.Then, from the mushroom fermentation is completed by the culture is extracted by hot water extraction or hot water extraction and ethanol treatment. More preferably, the mushroom fermented product of which the culture is completed is obtained by extracting hot water 1 to 7 times at 90 to 130 ° C. for 20 minutes to 2 hours, and then preparing 1 to 3 times the amount of ethanol.
본 발명에서 독활은 묵은 뿌리를 10%이하로 건조한 다음, 쌀뜨물에 12시간 담근 다음 껍질을 벗긴 다음 2 내지 3 mm의 두께로 썰어서 양지에서 말린 것을 사용한다. 이러한 가공으로 내장되어 있는 독성분을 제거하는 동시에 유효한 성분이 쉽게 우러나기 위한 것이다.In the present invention, the poisonous roots are dried to less than 10% of the old roots, soaked in rice water for 12 hours and then peeled and then sliced to a thickness of 2 to 3 mm to use dried in the sun. This process removes the toxic substances contained in the process and at the same time makes it easier to extract the active ingredients.
본 발명에서 하수오와 어성초는 껍질을 벗긴 다음 음지에서 수분 함량 10%이하로 건조 처리한 것을 사용하였다. 하수오와 어성초의 외피에는 독성이 일부 포함되어 있어 이것을 제거하며, 음건하여 내부성분의 농축과 유효성분이 효과적으로 우러나오게 하기 위한 것이다.
In the present invention, sewage and eoseongcho was used after peeling and dried to less than 10% moisture content in the shade. The outer skin of sewage and eoseongcho contains some toxicity, so it is removed, and it is intended for effective concentration of the active ingredients and concentration of the internal components in the shade.
RBC :적혈구 WBC : 백혈구RBC: Red Blood Cell WBC: White Blood Cell
Claims (7)
Fermented extract powder, poisonous licorice, licorice, eoseongcho, cheongung, cinnamon, triticale, mulberry leaf, ginseng, Astragalus, Angelica, Seokchangpo, hoo, bongsu, sewage, clove based on the total weight of 13.3, 9,1, 8.4 Herbal composition with human immunostimulating and activating function, formulated at 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4, 2.5%.
균질혼합한 것을 연합기상에서 연합하는 공정,
연합된 원료를 제환하는 공정,
제환된 것을 70±2℃의 온도에서 수분함량 10중량%이하로 건조하는 공정,
충진포장하는 공정으로 이루어지는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.
Fermented extract of Lingzhi mushroom fruit, poisonous licorice, licorice, eoseongcho, cheongung, cinnamon, three hundred vinegar, mulberry leaf, ginseng, Astragalus, Angelica, Seokchangpo, hou, bongsu, sewage, clove based on the total weight of 13.3, 9,1, 8.4, 8.2, 8.1, 7.1, 6.7, 6.1, 5.1, 5.1, 4.7, 4.6, 3.9, 3.7, 3.4, 2.5% mixing process in a blender for 20 minutes,
Process of uniting homogeneous mixture on coalescence unit,
Reprocessing associated raw materials,
Process of drying the reclaimed to a moisture content of 10% by weight or less at a temperature of 70 ± 2 ℃,
A method of manufacturing a herbal composition having a human immune enhancing function and an activating function, which is a packing and packing process.
운지버섯 자실체 추출분말은 분말형태의 운지버섯(Coriolus versicolor) 자실체를 무기질과 유기영양소를 첨가하여 발효 혼합물을 제조하는 단계;
상기 발효 혼합물에 버섯 자실체 분말에 1 내지 5 중량%의 효모추출물, 펩톤 및 포도당을 첨가하여 제조된 액상 발효용 조성물에서 발효시키는 단계로 제조하는 것을 특징으로 하는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.
The method of claim 1,
The fingerlings of the fruiting body fruit extract powder is prepared by adding a fermentation mixture to the powdered fingerlings (Coriolus versicolor) fruiting body of inorganic and organic nutrients;
Herbal medicine with human immunostimulating and activating function, characterized in that the fermentation mixture prepared by the step of fermenting in a liquid fermentation composition prepared by adding 1 to 5% by weight of yeast extract, peptone and glucose to fruiting body powder Method of Preparation of the Composition.
상기 발효 혼합물은 버섯 자실체 분말에 3 내지 30 중량%의 톱밥, 미강(rice bran) 및 포도당을 첨가하여 제조하는 것을 특징으로 하는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.
The method of claim 3, wherein
The fermentation mixture is 3 to 30% by weight of the fruiting body powder of mushrooms, rice bran (rice bran) and glucose, characterized in that the manufacturing method of a herbal composition with human immune enhancement and activation function characterized in that the production.
발효는 정치, 진탕 발효이며, 20 내지 37℃에서 1 내지 15일간 행해지는 것을 특징으로 하는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.
The method of claim 3, wherein
Fermentation is a stationary, shaking fermentation, a method of producing a herbal composition having a human immune enhancing function and an activation function, which is carried out at 20 to 37 ℃ for 1 to 15 days.
독활은 묵은 뿌리를 10%이하로 건조한 다음, 쌀뜨물에 12시간 담근 다음 껍질을 벗긴 다음 2 내지 3 mm의 두께로 썰어서 양지에서 말린 것임을 특징으로 하는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.
The method of claim 2,
Toxicity is a herbal composition with human immunostimulating and activating functions, characterized in that dried roots are dried to less than 10%, immersed in rice water for 12 hours, peeled and then cut into 2 to 3 mm thick and dried in sunny place. Manufacturing method.
하수오와 어성초는 껍질을 벗긴 다음 음지에서 수분 함량 10중량%이하로 건조 처리한 것임을 특징으로 하는 인체 면역증진기능과 활성화기능을 갖는 생약조성물의 제조방법.The method of claim 2,
Sewage and eoseongcho peeled and then dried in a shade of less than 10% by weight of water content of the herbal medicine composition having an immune enhancing function and an activation function, characterized in that.
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CN103599206A (en) * | 2013-11-28 | 2014-02-26 | 山西丰源药业有限公司 | Chinese herbal medicine navel paste for treating diarrhea and stomachache of children and preparation method thereof |
KR101469807B1 (en) * | 2013-02-05 | 2014-12-05 | 주식회사 아이피어리스 | Cosmetic compositions containing fermented extracts of coriolus versicolor mushroom |
CN106237260A (en) * | 2016-09-12 | 2016-12-21 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of blood stasis dispelling of can effectively dispeling cold and preparation method thereof |
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KR100538983B1 (en) | 2004-03-22 | 2005-12-26 | 주식회사 안국약품식품사업부 | Pharmaceutical composition comprising the crude drug extract for improving liver function |
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KR100538983B1 (en) | 2004-03-22 | 2005-12-26 | 주식회사 안국약품식품사업부 | Pharmaceutical composition comprising the crude drug extract for improving liver function |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101469807B1 (en) * | 2013-02-05 | 2014-12-05 | 주식회사 아이피어리스 | Cosmetic compositions containing fermented extracts of coriolus versicolor mushroom |
CN103599206A (en) * | 2013-11-28 | 2014-02-26 | 山西丰源药业有限公司 | Chinese herbal medicine navel paste for treating diarrhea and stomachache of children and preparation method thereof |
CN106237260A (en) * | 2016-09-12 | 2016-12-21 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of blood stasis dispelling of can effectively dispeling cold and preparation method thereof |
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